Danio rerio

52 known processes

actn2

actinin, alpha 2

(Aliases: MGC123223,wu:fd44c03,zgc:123223)

actn2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle cell developmentGO:00550011150.989
skeletal muscle organ developmentGO:0060538780.987
striated muscle cell developmentGO:00550021080.985
actomyosin structure organizationGO:0031032530.980
striated muscle cell differentiationGO:00511461290.973
muscle structure developmentGO:00610611960.924
muscle organ developmentGO:00075171010.867
cellular component assembly involved in morphogenesisGO:00109271070.850
skeletal muscle tissue developmentGO:0007519670.832
muscle fiber developmentGO:0048747520.801
heart developmentGO:00075073130.796
organelle assemblyGO:00709251100.783
cellular component assemblyGO:00226071700.781
myofibril assemblyGO:0030239480.777
organelle organizationGO:00069962270.772
muscle cell differentiationGO:00426921390.760
cell projection organizationGO:00300302840.754
Human
cellular component biogenesisGO:00440851780.737
skeletal muscle fiber developmentGO:0048741350.715
actin filament based processGO:0030029640.710
muscle tissue developmentGO:00605371100.709
myotube cell developmentGO:0014904350.704
myotube differentiationGO:0014902450.649
adult behaviorGO:003053420.641
Fly
actin cytoskeleton organizationGO:0030036630.597
striated muscle tissue developmentGO:00147061100.588
regulation of muscle contractionGO:000693730.571
cellular component morphogenesisGO:00329893360.558
muscle contractionGO:0006936180.544
Mouse
single organism organelle organizationGO:19025891990.525
anatomical structure homeostasisGO:0060249360.483
larval developmentGO:000216420.474
chordate embryonic developmentGO:00430092710.414
ion transmembrane transportGO:0034220910.403
Human
behaviorGO:0007610740.387
Fly
blood circulationGO:0008015870.383
cell cycleGO:0007049930.383
Worm
embryonic heart tube developmentGO:00350501330.332
muscle system processGO:0003012200.314
Mouse
locomotionGO:00400113130.310
embryo development ending in birth or egg hatchingGO:00097922710.285
Worm
locomotory behaviorGO:0007626340.274
Fly
single organism localizationGO:19025782250.272
Human
cardiac muscle cell developmentGO:0055013200.268
sarcomere organizationGO:0045214260.246
cytoskeleton organizationGO:0007010960.224
signal transductionGO:00071654550.218
Mouse
transportGO:00068102200.215
Human
establishment of localizationGO:00512342440.211
Human
actin mediated cell contractionGO:007025210.204
regulation of actin filament based movementGO:190311510.195
catabolic processGO:0009056320.194
Worm
multicellular organismal reproductive processGO:0048609350.193
regulation of cell matrix adhesionGO:000195210.191
response to chemicalGO:00422213200.190
agingGO:000756820.187
cellular component movementGO:00069283350.187
regulation of metabolic processGO:00192223590.179
Mouse
heart loopingGO:0001947940.178
ribonucleoside monophosphate catabolic processGO:000915840.177
heart morphogenesisGO:00030071560.173
single organism transportGO:00447652060.168
Human
nuclear divisionGO:0000280230.168
Worm
nucleoside monophosphate catabolic processGO:000912540.167
wnt signaling pathwayGO:0016055800.160
sensory organ developmentGO:00074233930.158
muscle cell cellular homeostasisGO:004671650.158
heterocycle metabolic processGO:00464832900.157
Mouse
cell migrationGO:00164772370.156
somatic muscle developmentGO:000752540.139
tube morphogenesisGO:00352393490.136
morphogenesis of an epitheliumGO:00020093330.136
ventricular cardiac muscle tissue morphogenesisGO:005501020.132
protein metabolic processGO:00195381830.131
Worm
regulation of macromolecule metabolic processGO:00602553170.131
Mouse
maintenance of locationGO:005123540.124
actin filament based movementGO:003004810.113
mitotic nuclear divisionGO:0007067180.111
Worm
generation of neuronsGO:00486993850.110
mitochondrion organizationGO:000700540.110
central nervous system developmentGO:00074173870.109
cellular nitrogen compound biosynthetic processGO:00442712180.108
Mouse
cell part morphogenesisGO:00329902460.105
voluntary skeletal muscle contractionGO:000301040.103
gene expressionGO:00104672520.102
negative regulation of heart contractionGO:004582220.098
neuron differentiationGO:00301823530.097
meiotic nuclear divisionGO:000712640.097
negative regulation of blood circulationGO:190352320.096
organonitrogen compound metabolic processGO:1901564740.096
cardiac cell developmentGO:0055006210.095
inorganic cation transmembrane transportGO:0098662500.095
Human
negative regulation of cellular processGO:00485232830.094
Human
purine nucleoside monophosphate catabolic processGO:000912840.094
heart contractionGO:0060047710.093
system processGO:00030081850.092
Mouse
single organism behaviorGO:0044708240.091
Fly
cardiac muscle tissue developmentGO:0048738480.089
multi organism reproductive processGO:0044703360.088
regulation of biological qualityGO:00650082630.083
Human
response to external stimulusGO:00096052640.079
regulation of sodium ion transmembrane transporter activityGO:200064910.078
inorganic ion transmembrane transportGO:0098660570.073
Human
cell substrate adhesionGO:003158940.072
Human
positive regulation of biological processGO:00485182530.070
Human
macromolecule biosynthetic processGO:00090592270.069
Mouse
neuron developmentGO:00486662620.068
striated muscle contractionGO:0006941120.068
sequestering of metal ionGO:005123830.067
regulation of nucleoside metabolic processGO:000911820.067
embryonic organ developmentGO:00485683810.066
skeletal myofibril assemblyGO:001486670.066
cell morphogenesisGO:00009022890.065
biosynthetic processGO:00090582940.065
Mouse
cardiac muscle cell differentiationGO:0055007300.064
embryonic heart tube morphogenesisGO:00031431080.063
regulation of cellular metabolic processGO:00313233200.063
Mouse
regulation of multicellular organismal processGO:00512392770.063
mitotic cell cycle processGO:1903047480.062
Worm
neuron projection developmentGO:00311751800.061
cell projection assemblyGO:0030031640.060
Human
nucleobase containing compound biosynthetic processGO:00346542050.060
Mouse
ventricular cardiac muscle tissue developmentGO:000322930.058
skeletal muscle thin filament assemblyGO:003024040.058
cell morphogenesis involved in neuron differentiationGO:00486671630.057
regulation of sodium ion transmembrane transportGO:190230510.057
cellular biosynthetic processGO:00442492860.056
Mouse
smooth muscle contractionGO:000693920.056
regulation of blood circulationGO:1903522320.055
epithelial tube morphogenesisGO:00605621480.055
regulation of nucleotide metabolic processGO:0006140170.054
intracellular signal transductionGO:0035556850.053
proton transportGO:001599270.053
regulation of rna metabolic processGO:00512522240.051
Mouse
regulation of purine nucleotide catabolic processGO:003312120.050
regulation of cellular macromolecule biosynthetic processGO:20001122220.050
cardiocyte differentiationGO:0035051440.050
heart processGO:0003015710.049
cellular macromolecule metabolic processGO:00442603910.049
Mouse
transmembrane transportGO:00550851200.049
Human
cellular protein complex assemblyGO:0043623190.049
purine ribonucleoside monophosphate catabolic processGO:000916940.048
atp catabolic processGO:000620040.047
purine ribonucleotide metabolic processGO:0009150270.047
cellular aromatic compound metabolic processGO:00067252950.047
Mouse
eye developmentGO:00016542770.046
reproductionGO:0000003400.045
somitogenesisGO:0001756870.045
multicellular organismal signalingGO:0035637220.045
multi organism processGO:00517041340.045
regulation of multicellular organism growthGO:004001440.044
cardiac muscle fiber developmentGO:004873930.044
regulation of reproductive processGO:200024140.043
embryonic organ morphogenesisGO:00485622740.042
response to stressGO:00069502630.042
macromolecular complex subunit organizationGO:0043933740.041
Human
regulation of nitrogen compound metabolic processGO:00511712510.041
Mouse
digestive system developmentGO:00551232890.040
regulation of sarcomere organizationGO:006029720.039
cilium assemblyGO:0042384580.039
cell matrix adhesionGO:000716040.039
Human
multicellular organism growthGO:003526440.039
multicellular organism reproductionGO:0032504350.039
regulation of cellular component movementGO:0051270550.039
cardiac muscle cell contractionGO:008600310.038
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.038
small molecule metabolic processGO:0044281770.038
cell projection morphogenesisGO:00488582440.037
cation transportGO:0006812810.037
Human
protein complex subunit organizationGO:0071822460.035
Human
cardiac muscle tissue morphogenesisGO:005500870.035
regulation of macromolecule biosynthetic processGO:00105562250.035
Mouse
lipid storageGO:001991510.035
homeostatic processGO:00425921420.034
regulation of nucleobase containing compound metabolic processGO:00192192500.034
Mouse
action potentialGO:0001508190.033
cell morphogenesis involved in differentiationGO:00009041950.033
regionalizationGO:00030022740.033
positive regulation of transportGO:005105020.032
Human
regulation of cellular biosynthetic processGO:00313262450.032
Mouse
regulation of localizationGO:00328791040.032
Human
cation homeostasisGO:0055080330.031
twitch skeletal muscle contractionGO:001472140.031
cation transmembrane transportGO:0098655650.031
Human
negative regulation of protein phosphorylationGO:000193340.031
meiotic cell cycle processGO:190304630.031
cardiac atrium developmentGO:000323040.030
oocyte maturationGO:000155640.030
rna metabolic processGO:00160702190.030
Mouse
purine containing compound metabolic processGO:0072521290.029
taxisGO:00423301090.029
specification of symmetryGO:00097992040.029
neuron projection guidanceGO:0097485860.028
axon developmentGO:00615641660.028
stem cell differentiationGO:00488631170.028
rna biosynthetic processGO:00327741810.027
Mouse
developmental growthGO:00485891660.027
apical junction assemblyGO:004329710.027
reactive oxygen species biosynthetic processGO:190340910.027
phosphorus metabolic processGO:00067931090.027
nucleic acid metabolic processGO:00903042440.026
Mouse
macromolecule catabolic processGO:0009057150.026
Worm
mitotic cell cycleGO:0000278640.026
Worm
regulation of circadian rhythmGO:004275240.026
regulation of blood pressureGO:000821710.025
regulation of cardiac muscle contractionGO:005511720.025
locomotor rhythmGO:004547530.025
circulatory system processGO:0003013870.024
water homeostasisGO:003010440.024
negative regulation of biological processGO:00485193040.024
Human
nucleobase containing small molecule metabolic processGO:0055086320.024
nucleic acid templated transcriptionGO:00976591810.024
Mouse
negative regulation of gene expressionGO:0010629650.024
regulation of transcription dna templatedGO:00063552130.024
cytokinesisGO:000091030.023
organelle fissionGO:0048285230.023
Worm
growthGO:00400071740.023
regulation of system processGO:0044057400.023
myosin filament organizationGO:003103360.022
nitrogen compound metabolic processGO:00068073190.022
Mouse
determination of heart left right asymmetryGO:00613711170.022
modification dependent macromolecule catabolic processGO:004363230.022
regulation of transmembrane transporter activityGO:002289820.021
Human
regulation of nucleotide catabolic processGO:003081120.021
skeletal muscle myosin thick filament assemblyGO:003024150.021
digestive tract developmentGO:00485652650.021
immune system processGO:00023762410.021
cellular catabolic processGO:0044248270.021
organic cyclic compound biosynthetic processGO:19013622230.020
Mouse
carboxylic acid metabolic processGO:0019752220.020
digestive tract morphogenesisGO:00485462310.020
heterocycle biosynthetic processGO:00181302150.020
Mouse
head developmentGO:00603223030.020
brain developmentGO:00074202930.020
vasculature developmentGO:00019442780.020
axonogenesisGO:00074091520.020
ameboidal type cell migrationGO:00016671430.020
cellular macromolecule biosynthetic processGO:00346452240.020
regulation of locomotionGO:0040012550.019
cell motilityGO:00488702440.019
response to activityGO:0014823140.019
single organism cellular localizationGO:1902580460.019
cell cycle processGO:0022402530.019
Worm
ventricular cardiac myofibril assemblyGO:005500540.018
cellular monovalent inorganic cation homeostasisGO:003000420.018
aromatic compound biosynthetic processGO:00194382170.018
Mouse
regulation of gene expressionGO:00104682650.018
lipid homeostasisGO:005508830.018
regulation of heart growthGO:006042020.018
sexual reproductionGO:0019953360.018
nuclear transportGO:005116940.018
regulation of sequestering of calcium ionGO:005128240.018
sensory organ morphogenesisGO:00905962000.018
segmentationGO:0035282970.018
negative regulation of cellular metabolic processGO:0031324770.017
regulation of muscle system processGO:009025750.017
metal ion transportGO:0030001580.017
Human
actin filament organizationGO:0007015150.017
organic substance catabolic processGO:1901575280.017
Worm
regulation of signal transductionGO:00099662250.017
Mouse
nucleobase containing compound metabolic processGO:00061392740.017
Mouse
organelle localizationGO:0051640490.017
carbohydrate derivative metabolic processGO:1901135610.017
cardiac atrium morphogenesisGO:000320920.017
myosin filament assemblyGO:003103460.017
oxoacid metabolic processGO:0043436310.017
cell surface receptor signaling pathwayGO:00071663250.017
cell deathGO:00082191210.016
negative regulation of metabolic processGO:0009892860.016
regulation of metal ion transportGO:001095940.016
Human
regulation of cardiac muscle cell contractionGO:008600410.016
lipid digestionGO:004424130.016
cellular nitrogen compound metabolic processGO:00346412900.016
Mouse
cardiac muscle contractionGO:006004860.016
regulation of myotube differentiationGO:001083020.016
regulation of striated muscle contractionGO:000694220.015
cognitionGO:005089010.015
ribose phosphate metabolic processGO:0019693270.015
purine ribonucleoside metabolic processGO:0046128100.015
organophosphate metabolic processGO:0019637370.014
regulation of meiotic cell cycleGO:005144510.014
macromolecular complex assemblyGO:0065003350.014
Human
endocytosisGO:0006897160.014
regulation of dna templated transcription in response to stressGO:004362000.014
positive regulation of wound healingGO:009030310.014
blood vessel developmentGO:00015682460.014
regulation of organ growthGO:004662030.014
inositol lipid mediated signalingGO:004801720.013
reactive nitrogen species metabolic processGO:200105700.013
single organism reproductive processGO:0044702400.013
regulation of transporter activityGO:003240920.013
Human
cell migration involved in gastrulationGO:0042074790.013
regulation of skeletal muscle fiber developmentGO:004874220.013
amine metabolic processGO:000930820.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
receptor mediated endocytosisGO:000689860.013
peptidyl serine modificationGO:001820920.013
ion transportGO:00068111140.013
Human
somite developmentGO:0061053960.013
regulation of wound healingGO:006104120.012
wound healingGO:0042060900.012
ribonucleotide metabolic processGO:0009259270.012
regulation of cell projection assemblyGO:006049140.012
protein complex biogenesisGO:0070271300.012
Human
immune system developmentGO:00025201910.012
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.012
response to abiotic stimulusGO:00096281220.012
positive regulation of metabolic processGO:00098931080.012
guanosine containing compound metabolic processGO:190106840.012
organic cyclic compound metabolic processGO:19013603010.012
Mouse
positive regulation of cellular amine metabolic processGO:003324000.012
angiogenesisGO:00015251580.012
protein stabilizationGO:005082120.012
phosphate containing compound metabolic processGO:00067961080.012
positive regulation of cellular processGO:00485222010.012
Human
negative regulation of signal transductionGO:0009968940.012
striated muscle myosin thick filament assemblyGO:007168860.011
regulation of bone mineralizationGO:003050020.011
nucleoside metabolic processGO:0009116110.011
cell agingGO:000756920.011
cellular component disassemblyGO:002241110.011
axon guidanceGO:0007411860.011
transcription from rna polymerase ii promoterGO:0006366800.011
regulation of primary metabolic processGO:00800903110.011
Mouse
hydrogen transportGO:000681870.011
regulation of transmembrane transportGO:0034762180.011
Human
regulation of cellular amine metabolic processGO:003323800.011
ras protein signal transductionGO:000726570.011
regulation of membrane potentialGO:0042391230.011
Human
regulation of lipid catabolic processGO:005099420.011
muscle tissue morphogenesisGO:006041570.011
cell substrate adherens junction assemblyGO:000704510.011
Human
response to woundingGO:00096111160.011
protein catabolic processGO:003016370.010
Worm
deathGO:00162651210.010
regulation of skeletal muscle cell differentiationGO:200101410.010
gamete generationGO:0007276330.010
cellular ion homeostasisGO:0006873170.010
transcription dna templatedGO:00063511810.010
regulation of filopodium assemblyGO:005148920.010
neuroblast differentiationGO:001401610.010
central nervous system neuron differentiationGO:0021953740.010
establishment of protein localization to organelleGO:007259440.010
regulation of cellular phGO:003064110.010

actn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscle tissue diseaseDOID:6600.610
myopathyDOID:42300.610
heart diseaseDOID:11400.610
cardiovascular system diseaseDOID:128700.610
cardiomyopathyDOID:005070000.610
muscular diseaseDOID:008000000.610
disease of anatomical entityDOID:700.610
intrinsic cardiomyopathyDOID:006003600.610
musculoskeletal system diseaseDOID:1700.610
dilated cardiomyopathyDOID:1293000.046
immune system diseaseDOID:291400.019
nervous system diseaseDOID:86300.014
neuromuscular diseaseDOID:44000.014
charcot marie tooth disease type 2DOID:005053900.014
neuropathyDOID:87000.014
charcot marie tooth diseaseDOID:1059500.014
muscular dystrophyDOID:988400.010
limb girdle muscular dystrophyDOID:1172400.010