Danio rerio

0 known processes

actn4

actinin, alpha 4

(Aliases: zgc:63508,wu:fb53f05)

actn4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chordate embryonic developmentGO:00430092710.604
agingGO:000756820.305
single organism localizationGO:19025782250.304
central nervous system developmentGO:00074173870.301
negative regulation of cellular processGO:00485232830.298
maintenance of locationGO:005123540.253
gastrulationGO:00073692080.250
regulation of cellular metabolic processGO:00313233200.248
transportGO:00068102200.229
metal ion transportGO:0030001580.222
establishment of localizationGO:00512342440.215
muscle structure developmentGO:00610611960.211
homeostatic processGO:00425921420.192
embryo development ending in birth or egg hatchingGO:00097922710.189
biosynthetic processGO:00090582940.178
single organism transportGO:00447652060.174
brain developmentGO:00074202930.169
negative regulation of sequestering of calcium ionGO:005128340.158
single organism metabolic processGO:00447102170.158
negative regulation of kinase activityGO:003367340.151
autophagyGO:000691440.149
regionalizationGO:00030022740.136
digestive tract developmentGO:00485652650.134
regulation of striated muscle contractionGO:000694220.125
striated muscle cell differentiationGO:00511461290.124
ribosomal small subunit biogenesisGO:004227420.121
negative regulation of biological processGO:00485193040.117
cellular nitrogen compound metabolic processGO:00346412900.110
regulation of nucleic acid templated transcriptionGO:19035062130.110
sequestering of metal ionGO:005123830.109
stem cell maintenanceGO:001982740.107
cation transportGO:0006812810.106
inorganic cation transmembrane transportGO:0098662500.105
regulation of signal transduction by p53 class mediatorGO:190179690.104
regulation of nitrogen compound metabolic processGO:00511712510.103
regulation of metabolic processGO:00192223590.103
cellular component movementGO:00069283350.103
inorganic ion transmembrane transportGO:0098660570.098
head developmentGO:00603223030.096
organic cyclic compound metabolic processGO:19013603010.095
translational initiationGO:000641330.095
cell agingGO:000756920.091
response to chemicalGO:00422213200.091
erythrocyte differentiationGO:0030218540.089
regulation of developmental processGO:00507932470.086
tissue remodelingGO:004877140.085
aromatic compound biosynthetic processGO:00194382170.085
hindbrain developmentGO:0030902910.085
digestive system developmentGO:00551232890.083
regulation of cell cycleGO:0051726520.080
adherens junction organizationGO:003433240.079
regulation of biological qualityGO:00650082630.079
renal system developmentGO:0072001940.077
striated muscle tissue developmentGO:00147061100.077
response to external stimulusGO:00096052640.074
system processGO:00030081850.073
organelle organizationGO:00069962270.071
cell cycleGO:0007049930.071
cell projection organizationGO:00300302840.071
negative regulation of cell deathGO:0060548600.068
hemopoiesisGO:00300971830.068
muscle cell differentiationGO:00426921390.067
heterocycle biosynthetic processGO:00181302150.067
embryonic organ morphogenesisGO:00485622740.067
neuromast developmentGO:0048884460.067
regulation of rna biosynthetic processGO:20011412130.067
cellular macromolecule metabolic processGO:00442603910.066
nucleocytoplasmic transportGO:000691340.066
cell migrationGO:00164772370.065
regulation of autophagyGO:001050630.065
regulation of primary metabolic processGO:00800903110.063
response to bacteriumGO:0009617580.063
negative regulation of protein phosphorylationGO:000193340.061
cellular biosynthetic processGO:00442492860.061
calcium ion transport into cytosolGO:006040230.061
regulation of transcription dna templatedGO:00063552130.060
protein metabolic processGO:00195381830.059
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.058
regulation of cellular biosynthetic processGO:00313262450.058
negative regulation of protein kinase activityGO:000646940.056
somitogenesisGO:0001756870.056
organic substance biosynthetic processGO:19015762890.056
regulation of protein modification by small protein conjugation or removalGO:190332030.055
connective tissue developmentGO:0061448990.055
sensory organ developmentGO:00074233930.054
neuron differentiationGO:00301823530.054
blood circulationGO:0008015870.054
appendage morphogenesisGO:0035107560.053
lipid storageGO:001991510.053
positive regulation of transportGO:005105020.051
nitrogen compound metabolic processGO:00068073190.051
cell substrate adherens junction assemblyGO:000704510.051
response to organic substanceGO:00100331530.050
morphogenesis of an epitheliumGO:00020093330.049
organelle assemblyGO:00709251100.048
female sex differentiationGO:004666040.047
nucleic acid templated transcriptionGO:00976591810.046
heart contractionGO:0060047710.046
cellular aromatic compound metabolic processGO:00067252950.046
nuclear transportGO:005116940.046
rna metabolic processGO:00160702190.046
positive regulation of cytosolic calcium ion concentrationGO:000720440.046
cellular component biogenesisGO:00440851780.044
cellular response to chemical stimulusGO:00708871570.044
single organism organelle organizationGO:19025891990.044
cytosolic calcium ion transportGO:006040130.044
negative regulation of gene expressionGO:0010629650.043
myotube cell developmentGO:0014904350.043
positive regulation of cellular metabolic processGO:0031325940.043
adult behaviorGO:003053420.042
sensory system developmentGO:0048880760.042
reproductionGO:0000003400.041
multi organism processGO:00517041340.040
cellular component morphogenesisGO:00329893360.040
macromolecule modificationGO:00434121110.040
cellular response to endogenous stimulusGO:0071495680.039
organic cyclic compound biosynthetic processGO:19013622230.039
positive regulation of cell cycleGO:004578730.039
negative regulation of biosynthetic processGO:0009890550.038
cell cycle processGO:0022402530.038
stem cell differentiationGO:00488631170.038
nucleobase containing compound biosynthetic processGO:00346542050.038
angiogenesisGO:00015251580.037
transcription dna templatedGO:00063511810.037
striated muscle cell developmentGO:00550021080.037
developmental programmed cell deathGO:001062340.037
nucleic acid metabolic processGO:00903042440.037
heterocycle metabolic processGO:00464832900.037
mitotic cell cycle processGO:1903047480.036
transmembrane transportGO:00550851200.036
digestive tract morphogenesisGO:00485462310.036
locomotionGO:00400113130.036
regulation of receptor activityGO:001046920.035
positive regulation of metabolic processGO:00098931080.035
embryonic heart tube morphogenesisGO:00031431080.035
skeletal muscle tissue developmentGO:0007519670.035
growthGO:00400071740.035
tube morphogenesisGO:00352393490.035
regulation of nucleobase containing compound metabolic processGO:00192192500.035
cation transmembrane transportGO:0098655650.035
muscle tissue developmentGO:00605371100.035
regulation of localizationGO:00328791040.035
cognitionGO:005089010.035
lateral line system developmentGO:0048925760.035
positive regulation of biological processGO:00485182530.035
response to external biotic stimulusGO:0043207970.034
regulation of muscle contractionGO:000693730.034
regulation of macromolecule biosynthetic processGO:00105562250.034
ameboidal type cell migrationGO:00016671430.034
eye morphogenesisGO:00485921440.034
intracellular signal transductionGO:0035556850.033
dorsal ventral pattern formationGO:00099531250.033
catabolic processGO:0009056320.033
cell cycle g1 s phase transitionGO:004484310.033
regulation of protein ubiquitinationGO:003139630.032
rna biosynthetic processGO:00327741810.032
epithelial cell differentiationGO:00308551160.032
regulation of reproductive processGO:200024140.032
regulation of molecular functionGO:0065009700.032
eye developmentGO:00016542770.032
regulation of macromolecule metabolic processGO:00602553170.032
mitochondrion morphogenesisGO:007058420.032
positive regulation of translationGO:004572710.031
somite developmentGO:0061053960.031
cellular component assembly involved in morphogenesisGO:00109271070.031
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.031
blood vessel developmentGO:00015682460.031
embryonic cranial skeleton morphogenesisGO:0048701900.030
negative regulation of cellular metabolic processGO:0031324770.030
regulation of catalytic activityGO:0050790550.030
programmed cell deathGO:00125011190.030
positive regulation of cellular processGO:00485222010.030
gene expressionGO:00104672520.029
smooth muscle contractionGO:000693920.029
positive regulation of gene expressionGO:0010628710.029
regulation of phosphate metabolic processGO:0019220430.029
mitotic cell cycleGO:0000278640.029
regulation of biosynthetic processGO:00098892500.029
muscle organ developmentGO:00075171010.029
cellular response to organic substanceGO:00713101050.028
response to other organismGO:0051707970.028
lateral line developmentGO:0048882660.028
ras protein signal transductionGO:000726570.027
ovarian follicle developmentGO:000154120.027
cellular protein metabolic processGO:00442671290.027
immune system processGO:00023762410.027
regulation of organ growthGO:004662030.027
establishment of localization in cellGO:0051649770.026
organonitrogen compound metabolic processGO:1901564740.026
negative regulation of ras protein signal transductionGO:004658010.026
g1 s transition of mitotic cell cycleGO:000008210.026
regulation of cellular ketone metabolic processGO:001056570.025
regulation of extrinsic apoptotic signaling pathwayGO:200123630.025
nuclear exportGO:005116810.025
female gonad developmentGO:000858540.025
photoreceptor cell differentiationGO:0046530550.025
regulation of tube sizeGO:003515020.025
regulation of sequestering of calcium ionGO:005128240.025
regulation of translational initiationGO:000644610.025
larval developmentGO:000216420.025
myeloid cell differentiationGO:0030099860.024
regulation of cell developmentGO:00602841000.024
response to biotic stimulusGO:0009607970.024
negative regulation of nitrogen compound metabolic processGO:0051172590.024
immune system developmentGO:00025201910.024
cellular respirationGO:004533330.024
cellular response to dsrnaGO:007135910.023
regulation of cell migrationGO:0030334400.023
embryonic skeletal system developmentGO:0048706970.023
kidney developmentGO:0001822920.023
macromolecule biosynthetic processGO:00090592270.023
embryonic appendage morphogenesisGO:0035113300.023
regulation of cellular macromolecule biosynthetic processGO:20001122220.023
skeletal muscle organ developmentGO:0060538780.023
regulation of cellular amine metabolic processGO:003323800.023
guanosine containing compound metabolic processGO:190106840.023
actin cytoskeleton organizationGO:0030036630.023
guanosine containing compound catabolic processGO:190106920.023
muscle fiber developmentGO:0048747520.022
heart developmentGO:00075073130.022
organelle localizationGO:0051640490.022
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.022
protein destabilizationGO:003164810.022
anterior posterior pattern specificationGO:00099521520.022
regulation of filopodium assemblyGO:005148920.022
amine metabolic processGO:000930820.022
protein modification processGO:00362111000.022
microtubule organizing center organizationGO:003102310.021
response to ketoneGO:190165410.021
behaviorGO:0007610740.021
development of primary female sexual characteristicsGO:004654540.021
positive regulation of macromolecule metabolic processGO:0010604930.021
cellular component assemblyGO:00226071700.021
adherens junction assemblyGO:003433310.021
sequestering of calcium ionGO:005120830.021
positive regulation of catalytic activityGO:0043085250.020
regulation of dna damage response signal transduction by p53 class mediatorGO:004351640.020
centrosome duplicationGO:005129810.020
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.020
cellular amine metabolic processGO:004410620.020
negative regulation of mrna processingGO:005068610.020
negative regulation of metabolic processGO:0009892860.020
sarcomere organizationGO:0045214260.020
regulation of dna templated transcription in response to stressGO:004362000.020
single organism nuclear importGO:190259330.020
cellular response to extracellular stimulusGO:003166820.020
cellular response to stressGO:0033554620.020
multicellular organism growthGO:003526440.020
establishment of protein localization to organelleGO:007259440.019
cellular response to starvationGO:000926710.019
cell motilityGO:00488702440.019
toxin transportGO:190199820.019
cellular macromolecule biosynthetic processGO:00346452240.019
nuclear importGO:005117030.019
apoptotic process involved in developmentGO:190274220.019
regulation of nuclease activityGO:003206910.019
regulation of apoptotic processGO:0042981980.019
positive regulation of nitrogen compound metabolic processGO:0051173690.019
cellular response to oxygen levelsGO:007145310.018
water homeostasisGO:003010440.018
cellular homeostasisGO:0019725260.018
negative regulation of programmed cell deathGO:0043069580.018
carboxylic acid metabolic processGO:0019752220.018
gtp catabolic processGO:000618420.018
nucleobase containing compound metabolic processGO:00061392740.018
segmentationGO:0035282970.018
response to glucocorticoidGO:005138410.018
negative regulation of mrna metabolic processGO:190331230.018
positive regulation of cellular catabolic processGO:003133130.018
release of sequestered calcium ion into cytosolGO:005120930.018
pancreas developmentGO:0031016840.017
cell morphogenesisGO:00009022890.017
response to abiotic stimulusGO:00096281220.017
i kappab kinase nf kappab signalingGO:000724940.017
negative regulation of rna metabolic processGO:0051253480.017
regulation of multicellular organismal processGO:00512392770.017
stem cell developmentGO:0048864820.017
regulation of cellular component organizationGO:0051128860.017
cytoskeleton organizationGO:0007010960.017
response to stressGO:00069502630.017
viral processGO:001603210.017
cellular carbohydrate metabolic processGO:004426240.017
regulation of programmed cell deathGO:00430671010.017
cell surface receptor signaling pathwayGO:00071663250.017
organic substance transportGO:0071702580.017
embryonic heart tube developmentGO:00350501330.017
protein homooligomerizationGO:005126030.017
regulation of cellular protein metabolic processGO:0032268520.017
sensory organ morphogenesisGO:00905962000.017
neuron neuron synaptic transmissionGO:000727010.016
gtp metabolic processGO:004603940.016
regulation of protein phosphorylationGO:0001932180.016
heart loopingGO:0001947940.016
camera type eye morphogenesisGO:00485931080.016
peptidyl serine phosphorylationGO:001810510.016
retina development in camera type eyeGO:00600411460.016
regulation of cellular phGO:003064110.016
cellular response to organic cyclic compoundGO:0071407380.016
developmental growthGO:00485891660.016
embryonic organ developmentGO:00485683810.016
aorta developmentGO:003590440.016
regulation of wound healingGO:006104120.016
protein dephosphorylationGO:000647030.015
positive regulation of cellular component biogenesisGO:004408930.015
positive regulation of catabolic processGO:000989640.015
collagen fibril organizationGO:003019910.015
regulation of neurological system processGO:003164420.015
cellular response to nutrient levelsGO:003166920.015
lymph vessel developmentGO:0001945270.015
intracellular transportGO:0046907320.015
regulation of cytoplasmic transportGO:190364940.015
cell part morphogenesisGO:00329902460.015
negative regulation of mitosisGO:004583930.015
regulation of cellular amino acid metabolic processGO:000652100.015
cellular localizationGO:0051641970.015
regulation of rna metabolic processGO:00512522240.015
stem cell divisionGO:001714510.015
antimicrobial humoral responseGO:001973020.015
regulation of carbohydrate metabolic processGO:000610940.015
regulation of signalingGO:00230512350.015
multicellular organismal water homeostasisGO:005089110.015
negative regulation of cell motilityGO:2000146170.015
response to metal ionGO:0010038340.015
regulation of signal transductionGO:00099662250.015
response to endogenous stimulusGO:0009719830.014
ear morphogenesisGO:0042471640.014
cellular nitrogen compound biosynthetic processGO:00442712180.014
response to oxygen containing compoundGO:1901700550.014
regulation of organelle assemblyGO:190211540.014
mesenchyme developmentGO:00604851270.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
negative regulation of apoptotic processGO:0043066550.014
protein phosphorylationGO:0006468470.014
blood vessel morphogenesisGO:00485142160.014
response to transition metal nanoparticleGO:1990267280.014
negative regulation of macromolecule metabolic processGO:0010605760.014
somatic stem cell maintenanceGO:003501910.014
phagocytosis engulfmentGO:000691110.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
glial cell proliferationGO:001400940.014
regulation of notch signaling pathwayGO:0008593160.014
response to organic cyclic compoundGO:0014070510.013
regulation of nucleoside metabolic processGO:000911820.013
heart processGO:0003015710.013
developmental process involved in reproductionGO:0003006270.013
chemical homeostasisGO:0048878490.013
positive regulation of cell communicationGO:0010647560.013
regulation of gtpase activityGO:004308720.013
modification dependent protein catabolic processGO:001994130.013
muscle cell developmentGO:00550011150.013
anatomical structure homeostasisGO:0060249360.013
post anal tail morphogenesisGO:0036342190.013
regulation of multicellular organism growthGO:004001440.013
phagocytosisGO:000690930.013
protein targeting to nucleusGO:004474430.013
regulation of cardiac muscle contractionGO:005511720.013
negative regulation of mrna splicing via spliceosomeGO:004802510.013
multicellular organism reproductionGO:0032504350.013
cell cell junction organizationGO:0045216100.013
peptidyl serine modificationGO:001820920.013
negative regulation of cell migrationGO:0030336170.013
cellular protein modification processGO:00064641000.012
protein importGO:001703830.012
specification of organ identityGO:001009220.012
convergent extensionGO:00600261180.012
oxoacid metabolic processGO:0043436310.012
chloride transmembrane transportGO:190247640.012
organic hydroxy compound transportGO:0015850140.012
regulation of protein transportGO:005122330.012
urogenital system developmentGO:0001655970.012
response to corticosteroidGO:003196010.012
single organism intracellular transportGO:1902582250.012
peripheral nervous system developmentGO:0007422550.012
macromolecule localizationGO:0033036540.012
regulation of dna catabolic processGO:190362410.012
lateral inhibitionGO:004633110.012
positive regulation of multi organism processGO:004390230.012
cellular catabolic processGO:0044248270.012
negative regulation of rna biosynthetic processGO:1902679450.012
regulation of endothelial cell differentiationGO:004560130.012
cardiac conduction system developmentGO:000316110.012
cellular ketone metabolic processGO:0042180110.012
lipid homeostasisGO:005508830.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.012
leukocyte homeostasisGO:000177620.012
regulation of blood vessel sizeGO:005088020.012
apoptotic process involved in morphogenesisGO:006056120.012
cation homeostasisGO:0055080330.012
gamete generationGO:0007276330.012
ovulation cycleGO:004269820.012
mitochondrion organizationGO:000700540.011
determination of bilateral symmetryGO:00098552040.011
positive regulation of macromolecule biosynthetic processGO:0010557590.011
rna localizationGO:000640340.011
regulation of cell activationGO:005086510.011
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.011
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.011
regulation of mesoderm developmentGO:2000380110.011
regulation of membrane potentialGO:0042391230.011
ion transmembrane transportGO:0034220910.011
cell substrate junction assemblyGO:000704420.011
regulation of gtp catabolic processGO:003312420.011
cellular amino acid metabolic processGO:000652070.011
vasculature developmentGO:00019442780.011
enzyme linked receptor protein signaling pathwayGO:00071671060.011
convergent extension involved in gastrulationGO:0060027710.011
negative regulation of nuclear divisionGO:005178430.011
chemosensory behaviorGO:000763510.011
negative regulation of cell cycle processGO:001094890.011
regulation of bindingGO:005109830.011
kidney epithelium developmentGO:0072073230.011
neurological system processGO:0050877620.011
regulation of nucleotide catabolic processGO:003081120.011
phosphorus metabolic processGO:00067931090.011
cell proliferationGO:0008283800.011
cell migration involved in gastrulationGO:0042074790.011
pectoral fin developmentGO:0033339500.011
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.011
regulation of phosphorylationGO:0042325260.011
regulation of hydrolase activityGO:0051336280.011
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.010
cardiac muscle tissue developmentGO:0048738480.010
regulation of cell communicationGO:00106462320.010
regulation of gene expressionGO:00104682650.010
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.010
regulation of cellular component movementGO:0051270550.010
localization of cellGO:00516742440.010
apical junction assemblyGO:004329710.010
regulation of transferase activityGO:0051338160.010
positive regulation of epithelial cell proliferationGO:005067910.010
protein acetylationGO:000647320.010
exocrine pancreas developmentGO:0031017280.010
cellular response to hypoxiaGO:007145610.010
positive regulation of biosynthetic processGO:0009891680.010
pigmentationGO:0043473850.010
neuron projection guidanceGO:0097485860.010
regulation of anatomical structure sizeGO:0090066330.010
dna catabolic processGO:000630810.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
fin morphogenesisGO:0033334530.010
regulation of response to biotic stimulusGO:000283120.010

actn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.081
cancerDOID:16200.081
organ system cancerDOID:005068600.081
disease of metabolismDOID:001466700.035
inherited metabolic disorderDOID:65500.018
gastrointestinal system cancerDOID:311900.017
disease of anatomical entityDOID:700.015
intestinal cancerDOID:1015500.011
large intestine cancerDOID:567200.011
hematopoietic system diseaseDOID:7400.011
anemiaDOID:235500.011
immune system diseaseDOID:291400.011