Danio rerio

0 known processes

sgpl1

sphingosine-1-phosphate lyase 1

(Aliases: zgc:162153)

sgpl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
maintenance of locationGO:005123540.347
biosynthetic processGO:00090582940.255
regulation of biosynthetic processGO:00098892500.238
regulation of innate immune responseGO:0045088110.227
response to ketoneGO:190165410.208
triglyceride homeostasisGO:007032820.199
lipid homeostasisGO:005508830.189
regulation of fatty acid metabolic processGO:001921710.159
larval developmentGO:000216420.156
regulation of metabolic processGO:00192223590.139
lipid storageGO:001991510.136
aromatic compound biosynthetic processGO:00194382170.124
regulation of gene expressionGO:00104682650.123
regulation of transcription dna templatedGO:00063552130.122
small molecule metabolic processGO:0044281770.118
heterocycle metabolic processGO:00464832900.109
immune system processGO:00023762410.108
Mouse
cellular nitrogen compound metabolic processGO:00346412900.103
cellular response to lipopolysaccharideGO:007122230.102
response to chemicalGO:00422213200.102
organic cyclic compound metabolic processGO:19013603010.101
Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.099
gene expressionGO:00104672520.095
regulation of cellular biosynthetic processGO:00313262450.094
organic substance biosynthetic processGO:19015762890.094
agingGO:000756820.094
signal transductionGO:00071654550.091
Mouse
cellular response to lipidGO:0071396390.090
nucleobase containing compound metabolic processGO:00061392740.089
nitrogen compound metabolic processGO:00068073190.089
Mouse
response to alkaloidGO:004327920.089
regulation of macromolecule metabolic processGO:00602553170.088
regulation of cellular macromolecule biosynthetic processGO:20001122220.086
regulation of cellular metabolic processGO:00313233200.085
gtp metabolic processGO:004603940.084
single organism metabolic processGO:00447102170.082
Mouse
cellular aromatic compound metabolic processGO:00067252950.081
response to steroid hormoneGO:0048545350.081
guanosine containing compound catabolic processGO:190106920.081
response to stressGO:00069502630.081
rna biosynthetic processGO:00327741810.079
cellular ketone metabolic processGO:0042180110.079
regulation of macromolecule biosynthetic processGO:00105562250.077
proteolysisGO:0006508380.077
programmed cell deathGO:00125011190.076
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.076
regulation of inflammatory responseGO:005072720.076
regulation of primary metabolic processGO:00800903110.072
cell migrationGO:00164772370.071
Mouse
cellular response to biotic stimulusGO:007121630.071
positive regulation of transportGO:005105020.070
regulation of biological qualityGO:00650082630.068
Mouse
regulation of nitrogen compound metabolic processGO:00511712510.067
positive regulation of cellular processGO:00485222010.067
regulation of response to stimulusGO:00485832690.065
guanosine containing compound metabolic processGO:190106840.064
cellular macromolecule metabolic processGO:00442603910.063
macromolecule biosynthetic processGO:00090592270.063
protein import into nucleusGO:000660630.062
positive regulation of nitrogen compound metabolic processGO:0051173690.061
nucleic acid metabolic processGO:00903042440.060
multicellular organism growthGO:003526440.059
Mouse
heterocycle biosynthetic processGO:00181302150.059
acylglycerol homeostasisGO:005509020.059
nucleobase containing compound biosynthetic processGO:00346542050.058
response to other organismGO:0051707970.058
transcription dna templatedGO:00063511810.057
regulation of cell communicationGO:00106462320.056
apoptotic processGO:00069151160.055
cellular nitrogen compound biosynthetic processGO:00442712180.055
regulation of protein transportGO:005122330.055
carboxylic acid metabolic processGO:0019752220.055
cellular response to chemical stimulusGO:00708871570.054
protein localization to nucleusGO:003450430.054
adult behaviorGO:003053420.053
response to external biotic stimulusGO:0043207970.052
response to woundingGO:00096111160.052
system processGO:00030081850.050
cellular macromolecule biosynthetic processGO:00346452240.050
regulation of rna biosynthetic processGO:20011412130.049
localization of cellGO:00516742440.049
Mouse
regulation of rna metabolic processGO:00512522240.048
organic cyclic compound biosynthetic processGO:19013622230.048
gtp catabolic processGO:000618420.048
transportGO:00068102200.048
transmembrane transportGO:00550851200.047
nucleocytoplasmic transportGO:000691340.047
regulation of tube sizeGO:003515020.047
response to lipidGO:0033993600.047
regulation of signal transductionGO:00099662250.047
response to external stimulusGO:00096052640.046
i kappab kinase nf kappab signalingGO:000724940.046
rna metabolic processGO:00160702190.046
nucleic acid templated transcriptionGO:00976591810.046
cognitionGO:005089010.046
organelle organizationGO:00069962270.045
positive regulation of gtp catabolic processGO:003312610.045
cellular biosynthetic processGO:00442492860.044
negative regulation of biological processGO:00485193040.044
locomotionGO:00400113130.043
Mouse
organonitrogen compound metabolic processGO:1901564740.043
positive regulation of cytosolic calcium ion concentrationGO:000720440.043
cellular response to external stimulusGO:007149620.043
regulation of cellular ketone metabolic processGO:001056570.043
homeostatic processGO:00425921420.043
single organism localizationGO:19025782250.043
fatty acid biosynthetic processGO:000663340.042
protein metabolic processGO:00195381830.042
negative regulation of defense responseGO:003134820.042
organic acid metabolic processGO:0006082310.042
head developmentGO:00603223030.041
Mouse
regulation of nucleotide catabolic processGO:003081120.040
heart developmentGO:00075073130.039
protein targeting to nucleusGO:004474430.039
cell motilityGO:00488702440.039
Mouse
cellular lipid metabolic processGO:0044255360.039
protein importGO:001703830.038
phosphorus metabolic processGO:00067931090.038
positive regulation of biological processGO:00485182530.038
defense responseGO:0006952470.038
negative regulation of cellular processGO:00485232830.037
xenobiotic metabolic processGO:000680540.037
response to hormoneGO:0009725480.036
positive regulation of catabolic processGO:000989640.035
regulation of establishment of protein localizationGO:007020140.034
long chain fatty acid metabolic processGO:000167610.034
lipid catabolic processGO:001604240.034
positive regulation of blood circulationGO:190352420.033
positive regulation of purine nucleotide catabolic processGO:003312310.033
lipid oxidationGO:003444010.033
alcohol biosynthetic processGO:004616520.033
establishment of protein localization to organelleGO:007259440.033
amine metabolic processGO:000930820.032
carboxylic acid catabolic processGO:004639530.032
cell surface receptor signaling pathwayGO:00071663250.032
Mouse
cellular component movementGO:00069283350.032
Mouse
positive regulation of cellular metabolic processGO:0031325940.032
digestive system developmentGO:00551232890.032
regulation of purine nucleotide catabolic processGO:003312120.032
regulation of signalingGO:00230512350.032
inflammatory responseGO:000695480.032
mitochondrion organizationGO:000700540.032
regulation of hydrolase activityGO:0051336280.031
transcription from rna polymerase ii promoterGO:0006366800.031
single organism nuclear importGO:190259330.031
regulation of protein targetingGO:190353320.031
regulation of protein import into nucleusGO:004230620.031
positive regulation of nucleotide catabolic processGO:003081310.031
regulation of i kappab kinase nf kappab signalingGO:004312240.031
regulation of cellular amine metabolic processGO:003323800.031
response to endogenous stimulusGO:0009719830.031
cellular response to hormone stimulusGO:0032870390.031
response to drugGO:004249330.031
phagocytosisGO:000690930.031
establishment of localizationGO:00512342440.031
cellular localizationGO:0051641970.031
positive regulation of defense responseGO:003134990.030
intracellular signal transductionGO:0035556850.030
multicellular organismal metabolic processGO:004423620.030
nuclear importGO:005117030.030
response to bacteriumGO:0009617580.030
positive regulation of cellular catabolic processGO:003133130.030
organelle fusionGO:004828430.029
sequestering of metal ionGO:005123830.029
response to nutrientGO:000758430.029
positive regulation of cellular component biogenesisGO:004408930.029
response to xenobiotic stimulusGO:0009410450.029
regulation of behaviorGO:0050795240.029
regulation of gtp catabolic processGO:003312420.029
nuclear transportGO:005116940.028
g protein coupled receptor signaling pathwayGO:0007186740.028
ion homeostasisGO:0050801410.028
cellular amine metabolic processGO:004410620.028
calcium ion transport into cytosolGO:006040230.028
regulation of nucleoside metabolic processGO:000911820.028
chemical homeostasisGO:0048878490.028
deathGO:00162651210.027
cytosolic calcium ion transportGO:006040130.027
positive regulation of cell cycleGO:004578730.027
cellular response to steroid hormone stimulusGO:0071383310.027
positive regulation of macromolecule metabolic processGO:0010604930.027
vasculature developmentGO:00019442780.027
Mouse
regulation of bindingGO:005109830.027
negative regulation of protein transportGO:005122430.027
collagen metabolic processGO:003296320.027
tube morphogenesisGO:00352393490.027
chemotaxisGO:00069351040.027
positive regulation of secretion by cellGO:190353210.027
regulation of sequestering of calcium ionGO:005128240.026
single organism transportGO:00447652060.026
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.026
fertilizationGO:000956630.026
single organism biosynthetic processGO:0044711710.026
neutrophil migrationGO:1990266100.026
positive regulation of secretionGO:005104710.026
cellular response to extracellular stimulusGO:003166820.026
regulation of cell activationGO:005086510.026
sensory perception of chemical stimulusGO:000760630.026
blood vessel morphogenesisGO:00485142160.025
Mouse
positive regulation of immune effector processGO:000269930.025
negative regulation of secretionGO:005104820.025
immune responseGO:0006955280.025
response to vitaminGO:003327330.025
fat soluble vitamin metabolic processGO:000677540.025
phosphate containing compound metabolic processGO:00067961080.025
regulation of cytokine productionGO:000181730.025
positive regulation of nucleobase containing compound metabolic processGO:0045935690.025
response to organic substanceGO:00100331530.025
regulation of protein localization to nucleusGO:190018020.025
cellular response to organic substanceGO:00713101050.025
protein localization to plasma membraneGO:007265910.024
establishment of protein localization to plasma membraneGO:009000210.024
negative regulation of programmed cell deathGO:0043069580.024
regulation of gtpase activityGO:004308720.024
lipid metabolic processGO:0006629520.024
Mouse
negative regulation of sequestering of calcium ionGO:005128340.024
purine nucleotide metabolic processGO:0006163270.024
negative regulation of response to stimulusGO:00485851040.023
regulation of multicellular organismal processGO:00512392770.023
Mouse
regulation of developmental processGO:00507932470.023
Mouse
oxoacid metabolic processGO:0043436310.023
negative regulation of secretion by cellGO:190353120.023
peptide metabolic processGO:000651810.023
sequestering of calcium ionGO:005120830.023
protein secretionGO:000930610.023
regulation of programmed cell deathGO:00430671010.023
brain developmentGO:00074202930.023
endosomal transportGO:001619720.023
multi organism processGO:00517041340.023
Mouse
regulation of blood vessel sizeGO:005088020.023
cellular response to molecule of bacterial originGO:007121930.023
cytokinesisGO:000091030.022
multicellular organismal macromolecule metabolic processGO:004425920.022
cell deathGO:00082191210.022
lipid localizationGO:0010876110.022
blood vessel developmentGO:00015682460.022
Mouse
neuron differentiationGO:00301823530.022
regulation of transcription from rna polymerase ii promoterGO:00063571140.022
positive regulation of cytokine productionGO:000181920.022
innate immune responseGO:0045087130.022
apoptotic signaling pathwayGO:0097190230.022
regulation of extrinsic apoptotic signaling pathwayGO:200123630.022
ion transmembrane transportGO:0034220910.022
cell migration involved in gastrulationGO:0042074790.021
single organism membrane fusionGO:004480120.021
regulation of homeostatic processGO:003284490.021
wound healingGO:0042060900.021
monocarboxylic acid catabolic processGO:007232930.021
regulation of cellular amino acid metabolic processGO:000652100.021
monocarboxylic acid biosynthetic processGO:0072330120.021
positive regulation of cellular amine metabolic processGO:003324000.021
regulation of blood pressureGO:000821710.021
positive regulation of nucleoside metabolic processGO:004597910.021
monocarboxylic acid metabolic processGO:0032787170.021
positive regulation of lipid metabolic processGO:004583410.020
organic hydroxy compound transportGO:0015850140.020
cellular protein metabolic processGO:00442671290.020
regulation of cytoplasmic transportGO:190364940.020
positive regulation of i kappab kinase nf kappab signalingGO:004312330.020
epithelial cell differentiationGO:00308551160.020
regulation of molecular functionGO:0065009700.020
regulation of endopeptidase activityGO:0052548230.020
regulation of apoptotic processGO:0042981980.020
embryonic organ developmentGO:00485683810.020
regulation of nucleic acid templated transcriptionGO:19035062130.020
neuron developmentGO:00486662620.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
cellular amino acid metabolic processGO:000652070.020
negative regulation of metabolic processGO:0009892860.020
response to organic cyclic compoundGO:0014070510.020
intracellular receptor signaling pathwayGO:0030522300.020
organic acid catabolic processGO:001605430.020
cellular protein modification processGO:00064641000.020
toll like receptor signaling pathwayGO:000222440.019
regulation of cell deathGO:00109411030.019
digestive tract developmentGO:00485652650.019
cellular response to xenobiotic stimulusGO:0071466350.019
smooth muscle contractionGO:000693920.019
cellular response to nutrient levelsGO:003166920.019
embryo development ending in birth or egg hatchingGO:00097922710.019
negative regulation of cytokine productionGO:000181810.019
symbiosis encompassing mutualism through parasitismGO:004440340.019
small molecule catabolic processGO:004428230.019
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
regulation of sterol transportGO:003237130.019
nucleoside phosphate metabolic processGO:0006753280.019
cellular response to endogenous stimulusGO:0071495680.018
neuroblast proliferationGO:000740520.018
autophagyGO:000691440.018
release of sequestered calcium ion into cytosolGO:005120930.018
taxisGO:00423301090.018
regulation of hormone secretionGO:004688320.018
angiogenesisGO:00015251580.018
positive regulation of inflammatory responseGO:005072910.018
digestive system processGO:002260090.018
cellular lipid catabolic processGO:004424230.018
digestionGO:0007586110.018
antimicrobial humoral responseGO:001973020.017
positive regulation of biosynthetic processGO:0009891680.017
peptide transportGO:001583310.017
cellular component biogenesisGO:00440851780.017
positive regulation of gtpase activityGO:004354710.017
central nervous system developmentGO:00074173870.017
response to hexoseGO:000974630.017
response to biotic stimulusGO:0009607970.017
hindbrain developmentGO:0030902910.017
retina development in camera type eyeGO:00600411460.017
regulation of nucleocytoplasmic transportGO:004682220.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
rna localizationGO:000640340.017
negative regulation of mapk cascadeGO:004340940.017
cellular response to stressGO:0033554620.017
positive regulation of cell activationGO:005086710.017
negative regulation of cell deathGO:0060548600.017
neuron neuron synaptic transmissionGO:000727010.017
organic substance transportGO:0071702580.017
regulation of lipase activityGO:006019120.017
protein polymerizationGO:005125840.017
membrane fusionGO:006102520.017
regulation of metal ion transportGO:001095940.017
cellular amide metabolic processGO:004360340.016
meiotic nuclear divisionGO:000712640.016
multicellular organismal response to stressGO:003355520.016
positive regulation of catalytic activityGO:0043085250.016
positive regulation of gene expressionGO:0010628710.016
organophosphate metabolic processGO:0019637370.016
regulation of protein complex assemblyGO:004325430.016
small molecule biosynthetic processGO:0044283160.016
positive regulation of leukocyte mediated immunityGO:000270510.016
positive regulation of nucleic acid templated transcriptionGO:1903508570.016
peptidyl serine phosphorylationGO:001810510.016
regulation of phosphorus metabolic processGO:0051174430.016
neutrophil chemotaxisGO:0030593100.016
hepaticobiliary system developmentGO:0061008980.016
peptidyl serine modificationGO:001820920.016
stem cell maintenanceGO:001982740.016
gastrulationGO:00073692080.016
positive regulation of metabolic processGO:00098931080.016
cell substrate adhesionGO:003158940.016
interspecies interaction between organismsGO:004441940.016
regulation of systemic arterial blood pressureGO:000307310.016
inorganic ion transmembrane transportGO:0098660570.016
internal peptidyl lysine acetylationGO:001839320.016
regulation of ion transmembrane transporter activityGO:003241220.016
regulation of lipid transportGO:003236840.016
positive regulation of transcription dna templatedGO:0045893570.016
single organism organelle organizationGO:19025891990.015
actomyosin structure organizationGO:0031032530.015
b cell activationGO:004211320.015
positive regulation of neuron apoptotic processGO:004352510.015
exocytosisGO:000688710.015
muscle cell differentiationGO:00426921390.015
lipid biosynthetic processGO:0008610220.015
regulation of carbohydrate metabolic processGO:000610940.015
regulation of protein bindingGO:004339330.015
regulation of intracellular protein transportGO:003315730.015
regulation of cellular component organizationGO:0051128860.015
positive regulation of cellular biosynthetic processGO:0031328680.015
hormone transportGO:000991420.015
sensory organ developmentGO:00074233930.015
generation of neuronsGO:00486993850.015
response to glucoseGO:000974930.015
carbohydrate derivative metabolic processGO:1901135610.015
regulation of epidermis developmentGO:004568220.015
secondary metabolic processGO:001974830.015
golgi vesicle transportGO:004819330.014
modification dependent macromolecule catabolic processGO:004363230.014
positive regulation of dna metabolic processGO:005105410.014
embryonic heart tube developmentGO:00350501330.014
compound eye developmentGO:004874920.014
cell proliferationGO:0008283800.014
regulation of multicellular organismal developmentGO:20000262230.014
regulation of multicellular organismal metabolic processGO:004424620.014
response to carbohydrateGO:000974330.014
negative regulation of apoptotic processGO:0043066550.014
regulation of dna replicationGO:000627530.014
negative regulation of catabolic processGO:000989530.014
regulation of protein maturationGO:1903317100.014
organic acid biosynthetic processGO:0016053120.014
macromolecule localizationGO:0033036540.014
specification of symmetryGO:00097992040.014
extrinsic apoptotic signaling pathwayGO:009719130.014
leukocyte mediated cytotoxicityGO:000190910.014
regulation of reproductive processGO:200024140.014
cellular component disassemblyGO:002241110.014
regulation of protein ubiquitinationGO:003139630.014
negative regulation of intracellular protein transportGO:009031730.014
regulation of defense responseGO:0031347140.014
inositol lipid mediated signalingGO:004801720.014
synaptic growth at neuromuscular junctionGO:005112420.014
ion transportGO:00068111140.014
sleepGO:003043110.014
energy reserve metabolic processGO:000611220.014
regulation of transporter activityGO:003240920.014
regulation of multicellular organism growthGO:004001440.014
Mouse
stem cell divisionGO:001714510.014
cellular response to organic cyclic compoundGO:0071407380.014
inorganic anion transportGO:0015698250.014
cytoskeleton organizationGO:0007010960.014
small gtpase mediated signal transductionGO:000726480.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
phosphatidylinositol mediated signalingGO:004801520.013
regulation of positive chemotaxisGO:005092640.013
steroid hormone mediated signaling pathwayGO:004340190.013
cellular divalent inorganic cation homeostasisGO:0072503130.013
determination of left right symmetryGO:00073681790.013
determination of bilateral symmetryGO:00098552040.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
cation transportGO:0006812810.013
eye developmentGO:00016542770.013
regulation of production of molecular mediator of immune responseGO:000270010.013
regulation of cholesterol transportGO:003237430.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
meiotic cell cycle processGO:190304630.013
cellular response to starvationGO:000926710.013
purine ribonucleotide metabolic processGO:0009150270.013
circadian sleep wake cycleGO:004274520.013
organelle assemblyGO:00709251100.013
phagocytosis engulfmentGO:000691110.013
response to amphetamineGO:000197510.013
regulation of phGO:000688530.013
regulation of synapse assemblyGO:005196330.013
regulation of transmembrane transporter activityGO:002289820.013
regulation of synaptic plasticityGO:004816710.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
liver developmentGO:0001889960.012
embryonic organ morphogenesisGO:00485622740.012
spermatid developmentGO:000728620.012
fatty acid transportGO:001590810.012
positive regulation of signal transductionGO:0009967560.012
nucleoside monophosphate catabolic processGO:000912540.012
fatty acid catabolic processGO:000906210.012
negative regulation of protein phosphorylationGO:000193340.012
cation homeostasisGO:0055080330.012
response to molecule of bacterial originGO:0002237140.012
positive regulation of cell communicationGO:0010647560.012
negative regulation of cellular metabolic processGO:0031324770.012
macromolecular complex subunit organizationGO:0043933740.012
positive regulation of hydrolase activityGO:0051345130.012
stem cell differentiationGO:00488631170.012
gland developmentGO:00487321430.012
protein complex disassemblyGO:004324110.012
response to abiotic stimulusGO:00096281220.012
establishment of localization in cellGO:0051649770.012
modification dependent protein catabolic processGO:001994130.012
neurological system processGO:0050877620.012
hatchingGO:003518840.012
regulation of response to biotic stimulusGO:000283120.012
protein modification processGO:00362111000.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
regulation of intracellular signal transductionGO:1902531570.012
neurotransmitter secretionGO:000726920.012
hormone secretionGO:004687920.012
regulation of tyrosine phosphorylation of stat proteinGO:004250910.012
single fertilizationGO:000733830.012
digestive tract morphogenesisGO:00485462310.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
positive regulation of cell divisionGO:005178120.011
response to hydrogen peroxideGO:004254230.011
granulocyte migrationGO:0097530110.011
regulation of wound healingGO:006104120.011
positive regulation of rna metabolic processGO:0051254590.011
neural crest cell developmentGO:0014032620.011
collagen biosynthetic processGO:003296420.011
production of molecular mediator of immune responseGO:000244020.011
striated muscle cell developmentGO:00550021080.011
membrane invaginationGO:001032410.011
positive regulation of neuron deathGO:190121610.011
multicellular organismal reproductive processGO:0048609350.011
Mouse
atp catabolic processGO:000620040.011
cellular protein catabolic processGO:004425740.011
negative regulation of multi organism processGO:004390130.011
negative regulation of cellular catabolic processGO:003133030.011
regulation of collagen metabolic processGO:001071220.011
stem cell proliferationGO:007208940.011
muscle cell developmentGO:00550011150.011
positive regulation of multicellular organismal processGO:0051240520.011
regulation of response to external stimulusGO:0032101310.011
positive regulation of response to stimulusGO:0048584800.011
lymphocyte proliferationGO:004665110.011
positive regulation of lipase activityGO:006019310.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
fatty acid oxidationGO:001939510.011
regulation of protein metabolic processGO:0051246560.011
calcium ion importGO:007050940.011
neural crest cell differentiationGO:0014033720.011
negative regulation of macromolecule metabolic processGO:0010605760.011

sgpl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.051
nervous system diseaseDOID:86300.050
sensory system diseaseDOID:005015500.026
eye diseaseDOID:561400.026
eye and adnexa diseaseDOID:149200.026
cancerDOID:16200.020
disease of cellular proliferationDOID:1456600.020
disease of metabolismDOID:001466700.016
inherited metabolic disorderDOID:65500.013