Danio rerio

0 known processes

tjp1

tight junction protein 1 (zona occludens 1)

(Aliases: cb817)

tjp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell projection organizationGO:00300302840.862
sensory organ developmentGO:00074233930.849
cellular component biogenesisGO:00440851780.848
neuron differentiationGO:00301823530.747
cell part morphogenesisGO:00329902460.727
cell morphogenesisGO:00009022890.579
cell surface receptor signaling pathwayGO:00071663250.578
cellular component assemblyGO:00226071700.569
biosynthetic processGO:00090582940.554
cellular component morphogenesisGO:00329893360.480
cell projection morphogenesisGO:00488582440.478
neuron developmentGO:00486662620.460
generation of neuronsGO:00486993850.451
regulation of cellular component organizationGO:0051128860.418
regulation of cell shapeGO:000836010.403
negative regulation of biological processGO:00485193040.383
tube morphogenesisGO:00352393490.381
regulation of multicellular organismal developmentGO:20000262230.377
organic cyclic compound biosynthetic processGO:19013622230.366
regulation of cell morphogenesisGO:0022604420.342
regulation of cell projection organizationGO:0031344440.315
head developmentGO:00603223030.309
macromolecular complex assemblyGO:0065003350.305
regulation of cell morphogenesis involved in differentiationGO:0010769380.302
nitrogen compound metabolic processGO:00068073190.302
regulation of cell communicationGO:00106462320.296
regulation of multicellular organismal processGO:00512392770.292
morphogenesis of an epitheliumGO:00020093330.283
signal transductionGO:00071654550.282
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.273
maintenance of locationGO:005123540.270
eye developmentGO:00016542770.259
single organism localizationGO:19025782250.244
heart field specificationGO:000312810.244
positive regulation of biological processGO:00485182530.239
cell morphogenesis involved in differentiationGO:00009041950.238
single organism metabolic processGO:00447102170.181
protein complex biogenesisGO:0070271300.180
regulation of neural precursor cell proliferationGO:200017730.179
cellular biosynthetic processGO:00442492860.177
organonitrogen compound metabolic processGO:1901564740.175
neuron projection morphogenesisGO:00488121610.169
organic substance biosynthetic processGO:19015762890.164
epithelial cell morphogenesisGO:000338220.160
cell morphogenesis involved in neuron differentiationGO:00486671630.160
negative regulation of protein phosphorylationGO:000193340.157
organelle organizationGO:00069962270.157
gland developmentGO:00487321430.153
wnt signaling pathwayGO:0016055800.151
regulation of neuron projection developmentGO:0010975400.150
regulation of dendrite developmentGO:005077330.148
gastrulationGO:00073692080.148
regulation of cell differentiationGO:00455951420.148
negative regulation of cellular processGO:00485232830.147
vasculature developmentGO:00019442780.139
single organism organelle organizationGO:19025891990.137
glomerular basement membrane developmentGO:003283650.135
protein oligomerizationGO:005125970.134
lateral inhibitionGO:004633110.130
anterior posterior pattern specificationGO:00099521520.126
regulation of signalingGO:00230512350.126
positive regulation of cellular component biogenesisGO:004408930.125
regulation of biological qualityGO:00650082630.125
proximal distal pattern formationGO:000995410.124
regulation of rna biosynthetic processGO:20011412130.122
oxidation reduction processGO:0055114410.121
regulation of cell developmentGO:00602841000.118
muscle cell differentiationGO:00426921390.118
determination of bilateral symmetryGO:00098552040.117
neuron projection developmentGO:00311751800.114
regulation of organ growthGO:004662030.114
blood vessel morphogenesisGO:00485142160.114
rna biosynthetic processGO:00327741810.110
protein complex assemblyGO:0006461300.110
embryonic heart tube morphogenesisGO:00031431080.109
response to vitamin b3GO:003355220.109
heparan sulfate proteoglycan biosynthetic processGO:001501250.109
cell migration involved in heart developmentGO:0060973220.105
epithelial tube morphogenesisGO:00605621480.103
striated muscle cell developmentGO:00550021080.103
heparan sulfate proteoglycan metabolic processGO:003020160.102
negative regulation of stem cell differentiationGO:200073720.099
sensory organ morphogenesisGO:00905962000.099
cilium morphogenesisGO:0060271850.096
brain developmentGO:00074202930.094
transportGO:00068102200.093
regulation of signal transductionGO:00099662250.091
bmp signaling pathwayGO:0030509520.090
heart loopingGO:0001947940.089
striated muscle cell differentiationGO:00511461290.088
lipid storageGO:001991510.086
regulation of localizationGO:00328791040.086
cardiac muscle tissue developmentGO:0048738480.085
regulation of extrinsic apoptotic signaling pathwayGO:200123630.085
regulation of neurogenesisGO:0050767870.085
regulation of intracellular protein transportGO:003315730.085
single organism reproductive processGO:0044702400.084
regulation of response to stimulusGO:00485832690.083
positive regulation of cell fate commitmentGO:001045510.082
positive regulation of neural precursor cell proliferationGO:200017910.081
neuron projection extensionGO:1990138450.081
actin filament based processGO:0030029640.079
patterning of blood vesselsGO:0001569150.079
carboxylic acid metabolic processGO:0019752220.077
protein metabolic processGO:00195381830.077
muscle cell developmentGO:00550011150.076
nephron epithelium morphogenesisGO:007208810.075
regulation of cardiac muscle tissue developmentGO:005502410.075
phagocytosisGO:000690930.073
embryonic organ developmentGO:00485683810.072
specification of symmetryGO:00097992040.072
cardiac cell fate commitmentGO:006091110.071
programmed cell deathGO:00125011190.071
spinal cord radial glial cell differentiationGO:002153120.069
segmentationGO:0035282970.069
negative regulation of kinase activityGO:003367340.069
cytoskeleton organizationGO:0007010960.067
developmental growth involved in morphogenesisGO:0060560860.067
defense responseGO:0006952470.066
embryonic heart tube developmentGO:00350501330.063
heart morphogenesisGO:00030071560.063
regulation of anatomical structure morphogenesisGO:00226031300.061
regulation of nervous system developmentGO:0051960900.059
regulation of striated muscle contractionGO:000694220.058
actin cytoskeleton organizationGO:0030036630.058
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.057
larval developmentGO:000216420.055
sulfur compound biosynthetic processGO:004427290.055
regulation of cellular macromolecule biosynthetic processGO:20001122220.055
embryonic organ morphogenesisGO:00485622740.054
neuroblast fate commitmentGO:001401710.053
system processGO:00030081850.053
commissural neuron axon guidanceGO:007167930.053
organic acid metabolic processGO:0006082310.053
developmental process involved in reproductionGO:0003006270.053
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.053
negative regulation of wnt signaling pathwayGO:0030178300.052
small molecule metabolic processGO:0044281770.050
biomineral tissue developmentGO:0031214130.049
positive regulation of nervous system developmentGO:0051962250.048
macromolecular complex subunit organizationGO:0043933740.048
cardiac ventricle developmentGO:000323190.047
neural crest cell differentiationGO:0014033720.047
cell motilityGO:00488702440.047
oxoacid metabolic processGO:0043436310.046
cilium movement involved in cell motilityGO:006029430.046
cell cell junction organizationGO:0045216100.046
multicellular organism growthGO:003526440.046
cellular component assembly involved in morphogenesisGO:00109271070.046
intracellular estrogen receptor signaling pathwayGO:003052030.045
mesenchyme developmentGO:00604851270.044
chordate embryonic developmentGO:00430092710.044
regulation of phospholipase c activityGO:190027410.043
regulation of production of molecular mediator of immune responseGO:000270010.043
regulation of cellular component movementGO:0051270550.042
nucleobase containing compound biosynthetic processGO:00346542050.041
cell fate commitmentGO:0045165990.041
regulation of synapse organizationGO:005080730.040
regulation of mesoderm developmentGO:2000380110.040
regulation of gene expressionGO:00104682650.040
cardiac atrium developmentGO:000323040.039
positive regulation of rna metabolic processGO:0051254590.039
regulation of developmental processGO:00507932470.039
cell migrationGO:00164772370.039
digestive system developmentGO:00551232890.039
hepaticobiliary system developmentGO:0061008980.038
regulation of cellular component biogenesisGO:0044087120.038
regulation of oligodendrocyte differentiationGO:004871310.037
regulation of protein ubiquitinationGO:003139630.037
regulation of cell substrate adhesionGO:001081010.037
regulation of wnt signaling pathwayGO:0030111530.037
entrainment of circadian clockGO:000964920.037
actomyosin structure organizationGO:0031032530.037
muscle fiber developmentGO:0048747520.036
regulation of macromolecule biosynthetic processGO:00105562250.036
regulation of synapse assemblyGO:005196330.036
positive regulation of phospholipase c activityGO:001086310.036
cellular amino acid metabolic processGO:000652070.035
proteoglycan biosynthetic processGO:0030166120.035
regulation of cellular component sizeGO:0032535300.035
regionalizationGO:00030022740.034
single organism transportGO:00447652060.034
immune system processGO:00023762410.033
atrioventricular valve formationGO:000319030.032
blood vessel developmentGO:00015682460.032
pituitary gland developmentGO:0021983160.032
developmental growthGO:00485891660.032
central nervous system developmentGO:00074173870.032
cellular hormone metabolic processGO:0034754190.031
regulation of mesodermal cell fate specificationGO:004266190.031
aromatic compound biosynthetic processGO:00194382170.031
negative regulation of response to stimulusGO:00485851040.030
regulation of stem cell differentiationGO:200073640.030
regulation of metabolic processGO:00192223590.030
synaptic growth at neuromuscular junctionGO:005112420.029
nucleic acid metabolic processGO:00903042440.029
regulation of axonogenesisGO:0050770320.029
cardiac muscle cell fate commitmentGO:006092310.029
camera type eye developmentGO:00430102220.029
determination of left right symmetryGO:00073681790.029
taxisGO:00423301090.028
cell deathGO:00082191210.028
reproductive processGO:0022414400.028
cardiac cell developmentGO:0055006210.028
response to abiotic stimulusGO:00096281220.028
arterial endothelial cell differentiationGO:006084220.027
single organismal cell cell adhesionGO:0016337290.027
positive regulation of cell fate specificationGO:004266010.027
regulation of heart growthGO:006042020.027
positive regulation of cell proliferationGO:0008284150.027
eye morphogenesisGO:00485921440.027
isoprenoid biosynthetic processGO:000829970.026
developmental cell growthGO:0048588520.026
neuroblast differentiationGO:001401610.025
dendrite developmentGO:001635890.025
negative regulation of epithelial cell proliferationGO:005068010.025
specification of organ identityGO:001009220.025
regulation of cytoplasmic transportGO:190364940.025
single organism biosynthetic processGO:0044711710.025
regulation of myelinationGO:003164110.024
positive regulation of gtpase activityGO:004354710.024
regulation of protein modification by small protein conjugation or removalGO:190332030.024
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.024
immune responseGO:0006955280.024
regulation of synaptic growth at neuromuscular junctionGO:000858210.024
cardiac conduction system developmentGO:000316110.024
amine metabolic processGO:000930820.024
adherens junction organizationGO:003433240.024
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.024
positive regulation of bmp signaling pathwayGO:0030513100.023
stem cell differentiationGO:00488631170.023
establishment of localizationGO:00512342440.023
gene expressionGO:00104672520.023
positive regulation of mesoderm developmentGO:200038210.023
protein complex subunit organizationGO:0071822460.023
positive regulation of gastrulationGO:200054320.023
glial cell fate determinationGO:000740310.023
ventricular cardiac muscle tissue morphogenesisGO:005501020.023
growthGO:00400071740.023
cardiac atrium morphogenesisGO:000320920.023
nephron morphogenesisGO:007202820.022
regulation of glial cell proliferationGO:006025140.022
regulation of sequence specific dna binding transcription factor activityGO:005109090.022
cell proliferation in forebrainGO:002184630.022
glucose importGO:004632320.022
defense response to gram negative bacteriumGO:005082980.022
regulation of inner ear receptor cell differentiationGO:200098010.021
positive regulation of jnk cascadeGO:004633030.021
positive regulation of transportGO:005105020.021
regulation of cell matrix adhesionGO:000195210.021
somite developmentGO:0061053960.021
embryo development ending in birth or egg hatchingGO:00097922710.020
epithelial cell differentiationGO:00308551160.020
regulation of embryonic developmentGO:0045995470.020
negative regulation of signal transductionGO:0009968940.020
diterpenoid biosynthetic processGO:001610270.020
cell matrix adhesionGO:000716040.020
actin mediated cell contractionGO:007025210.020
atrial ventricular junction remodelingGO:000329420.020
cardiac chamber developmentGO:0003205190.020
positive regulation of mesodermal cell fate specificationGO:004833710.019
regulation of biomineral tissue developmentGO:007016720.019
epithelial cell developmentGO:0002064420.019
biological adhesionGO:0022610400.019
regulation of cell deathGO:00109411030.019
localization of cellGO:00516742440.019
adenohypophysis developmentGO:0021984150.019
neuromast depositionGO:004888590.019
cellular component movementGO:00069283350.019
regulation of circadian rhythmGO:004275240.019
protein modification processGO:00362111000.019
cell cell signalingGO:0007267520.019
heart joggingGO:0003146400.019
agingGO:000756820.019
negative regulation of gene expressionGO:0010629650.019
liver developmentGO:0001889960.018
axonogenesisGO:00074091520.018
regulation of cell migration involved in sprouting angiogenesisGO:009004930.018
wnt signaling pathway planar cell polarity pathwayGO:006007140.018
macromolecule localizationGO:0033036540.018
cellular response to external stimulusGO:007149620.018
positive regulation of cellular protein metabolic processGO:0032270220.018
carbohydrate metabolic processGO:0005975120.018
proteoglycan metabolic processGO:0006029140.018
inner ear developmentGO:00488391260.017
single organism cell adhesionGO:0098602290.017
positive regulation of nucleoside metabolic processGO:004597910.017
regulation of stem cell proliferationGO:007209120.017
renal tubule morphogenesisGO:006133310.017
response to prostaglandinGO:003469450.017
establishment of localization in cellGO:0051649770.017
behaviorGO:0007610740.017
extrinsic apoptotic signaling pathwayGO:009719130.017
regulation of glial cell differentiationGO:004568540.017
positive regulation of immune effector processGO:000269930.017
regulation of protein import into nucleusGO:004230620.016
nephron tubule morphogenesisGO:007207810.016
regulation of cytokine productionGO:000181730.016
lipid metabolic processGO:0006629520.016
blood circulationGO:0008015870.016
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.016
axon extensionGO:0048675450.016
determination of heart left right asymmetryGO:00613711170.016
heart developmentGO:00075073130.016
cellular amine metabolic processGO:004410620.016
negative regulation of cardiac muscle tissue developmentGO:005502610.016
negative regulation of macromolecule metabolic processGO:0010605760.016
paraxial mesoderm developmentGO:004833980.016
transcription dna templatedGO:00063511810.016
formation of primary germ layerGO:0001704620.016
cell cell junction assemblyGO:000704350.015
cell projection assemblyGO:0030031640.015
ectodermal cell differentiationGO:001066820.015
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.015
chemotaxisGO:00069351040.015
regulation of bmp signaling pathwayGO:0030510390.015
macromolecule modificationGO:00434121110.015
convergent extensionGO:00600261180.015
heart valve formationGO:000318840.015
regulation of extent of cell growthGO:0061387290.015
phagocytosis engulfmentGO:000691110.015
epibolyGO:0090504410.015
negative regulation of cell fate specificationGO:0009996110.015
positive regulation of response to stimulusGO:0048584800.014
regulation of canonical wnt signaling pathwayGO:0060828340.014
regulation of cellular ketone metabolic processGO:001056570.014
positive regulation of locomotionGO:0040017140.014
negative regulation of axon regenerationGO:004868140.014
mesenchymal cell differentiationGO:0048762870.014
negative regulation of protein kinase activityGO:000646940.014
glomerulus vasculature developmentGO:007201220.014
regulation of dendrite morphogenesisGO:004881430.014
cilium assemblyGO:0042384580.014
ossificationGO:0001503230.014
heart valve morphogenesisGO:000317980.014
actin filament organizationGO:0007015150.014
hemopoiesisGO:00300971830.014
striated muscle cell proliferationGO:001485570.014
adherens junction assemblyGO:003433310.013
eye photoreceptor cell differentiationGO:0001754450.013
glial cell differentiationGO:0010001420.013
regulation of protein transportGO:005122330.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.013
production of molecular mediator of immune responseGO:000244020.013
positive regulation of muscle organ developmentGO:004863610.013
positive regulation of metabolic processGO:00098931080.013
negative regulation of embryonic developmentGO:0045992110.013
immune system developmentGO:00025201910.013
mesoderm developmentGO:0007498880.013
positive regulation of cellular metabolic processGO:0031325940.013
negative regulation of gastrulationGO:2000542110.013
ventricular cardiac muscle tissue developmentGO:000322930.013
negative regulation of cell differentiationGO:0045596460.012
regulation of rho protein signal transductionGO:003502320.012
forebrain neuron fate commitmentGO:002187710.012
regulation of primary metabolic processGO:00800903110.012
cell proliferationGO:0008283800.012
cardiocyte differentiationGO:0035051440.012
cardiac muscle cell proliferationGO:006003850.012
determination of left right asymmetry in lateral mesodermGO:0003140200.012
muscle contractionGO:0006936180.012
angiogenesisGO:00015251580.012
blood vessel endothelial cell differentiationGO:006083720.012
desmosome organizationGO:000293430.012
positive regulation of embryonic developmentGO:004001930.012
response to chemicalGO:00422213200.012
leukocyte proliferationGO:007066110.012
regulation of purine nucleotide catabolic processGO:003312120.012
positive regulation of leukocyte mediated immunityGO:000270510.012
regulation of establishment of protein localizationGO:007020140.012
positive regulation of multicellular organismal processGO:0051240520.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
negative regulation of mesodermal cell fate specificationGO:004266230.012
negative regulation of biosynthetic processGO:0009890550.012
positive regulation of neuron migrationGO:200122420.012
somitogenesisGO:0001756870.012
glycoprotein metabolic processGO:0009100230.012
urogenital system developmentGO:0001655970.012
inner ear receptor cell fate commitmentGO:006012040.011
retinoic acid metabolic processGO:004257390.011
regulation of cell proliferationGO:0042127370.011
endodermal cell fate determinationGO:000749320.011
digestive tract morphogenesisGO:00485462310.011
negative regulation of cell deathGO:0060548600.011
regulation of locomotionGO:0040012550.011
central nervous system myelinationGO:002201020.011
canonical wnt signaling pathway involved in heart developmentGO:006131610.011
regulation of cellular amine metabolic processGO:003323800.011
endothelial cell morphogenesisGO:000188610.011
negative regulation of neural precursor cell proliferationGO:200017810.011
bone mineralizationGO:003028290.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
cardiac muscle cell differentiationGO:0055007300.011
positive regulation of protein metabolic processGO:0051247230.011
negative regulation of developmental processGO:0051093650.011
regulation of gtpase activityGO:004308720.011
cell junction organizationGO:0034330110.011
cellular response to fatty acidGO:007139830.011
response to bacteriumGO:0009617580.011
positive regulation of cytokine productionGO:000181920.011
digestive tract developmentGO:00485652650.011
radial glial cell differentiationGO:006001920.011
epithelial cell morphogenesis involved in gastrulationGO:000338110.011
kidney developmentGO:0001822920.011
cellular response to prostaglandin stimulusGO:007137930.011
deathGO:00162651210.011
neuroblast proliferationGO:000740520.011
membrane invaginationGO:001032410.011
circulatory system processGO:0003013870.011
cellular protein catabolic processGO:004425740.011
positive regulation of notch signaling pathwayGO:004574730.011
diencephalon developmentGO:0021536580.011
regulation of reproductive processGO:200024140.011
nuclear importGO:005117030.011
cellular protein complex assemblyGO:0043623190.011
positive regulation of muscle tissue developmentGO:190186310.011
leukocyte chemotaxisGO:0030595120.011
nephron epithelium developmentGO:0072009160.010
mesoderm formationGO:0001707430.010
regulation of behaviorGO:0050795240.010
synaptic vesicle localizationGO:009747910.010
regulation of programmed cell deathGO:00430671010.010
mesodermal cell fate specificationGO:0007501120.010
small gtpase mediated signal transductionGO:000726480.010
regulation of protein metabolic processGO:0051246560.010
pronephros developmentGO:0048793690.010
regulation of developmental growthGO:0048638380.010

tjp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.435
nervous system diseaseDOID:86300.097
sensory system diseaseDOID:005015500.044
eye and adnexa diseaseDOID:149200.044
eye diseaseDOID:561400.044
bone development diseaseDOID:008000600.042
bone diseaseDOID:008000100.042
connective tissue diseaseDOID:6500.042
musculoskeletal system diseaseDOID:1700.042
disease of metabolismDOID:001466700.030
inherited metabolic disorderDOID:65500.016
organ system cancerDOID:005068600.013
intestinal cancerDOID:1015500.013
colon carcinomaDOID:152000.013
disease of cellular proliferationDOID:1456600.013
colorectal cancerDOID:925600.013
gastrointestinal system cancerDOID:311900.013
cancerDOID:16200.013
colon cancerDOID:21900.013
large intestine cancerDOID:567200.013