Danio rerio

0 known processes

ppa2

pyrophosphatase (inorganic) 2

(Aliases: zgc:77715,MGC77715)

ppa2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.099
agingGO:000756820.055
multicellular organism growthGO:003526440.053
maintenance of locationGO:005123540.043
cellular protein catabolic processGO:004425740.043
regulation of multicellular organism growthGO:004001440.042
cellular nitrogen compound metabolic processGO:00346412900.039
nitrogen compound metabolic processGO:00068073190.039
proteolysis involved in cellular protein catabolic processGO:005160330.039
regulation of macromolecule metabolic processGO:00602553170.039
cellular macromolecule metabolic processGO:00442603910.038
gene expressionGO:00104672520.038
meiotic nuclear divisionGO:000712640.038
modification dependent macromolecule catabolic processGO:004363230.037
modification dependent protein catabolic processGO:001994130.035
positive regulation of transportGO:005105020.035
positive regulation of cellular component biogenesisGO:004408930.034
establishment of protein localization to organelleGO:007259440.033
phagocytosisGO:000690930.033
proteasomal protein catabolic processGO:001049820.033
ubiquitin dependent protein catabolic processGO:000651130.033
regulation of protein complex assemblyGO:004325430.033
regulation of metabolic processGO:00192223590.033
lipid storageGO:001991510.032
heterocycle metabolic processGO:00464832900.031
rna metabolic processGO:00160702190.031
organic cyclic compound metabolic processGO:19013603010.031
regulation of mrna splicing via spliceosomeGO:004802430.030
stem cell maintenanceGO:001982740.030
regulation of primary metabolic processGO:00800903110.030
signal transductionGO:00071654550.029
amine metabolic processGO:000930820.029
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.029
cytokinesisGO:000091030.029
nucleobase containing compound metabolic processGO:00061392740.028
cellular biosynthetic processGO:00442492860.028
cellular amine metabolic processGO:004410620.028
response to chemicalGO:00422213200.028
nucleic acid metabolic processGO:00903042440.028
regulation of cellular macromolecule biosynthetic processGO:20001122220.028
nuclear transportGO:005116940.028
positive regulation of catabolic processGO:000989640.027
protein localization to nucleusGO:003450430.027
regulation of cellular amine metabolic processGO:003323800.027
regulation of protein transportGO:005122330.026
macromolecule biosynthetic processGO:00090592270.026
organic substance biosynthetic processGO:19015762890.026
negative regulation of biological processGO:00485193040.026
positive regulation of cellular catabolic processGO:003133130.026
regulation of protein catabolic processGO:004217610.026
regulation of gene expressionGO:00104682650.026
regulation of establishment of protein localizationGO:007020140.025
cellular nitrogen compound biosynthetic processGO:00442712180.025
cellular response to external stimulusGO:007149620.025
regulation of mrna processingGO:005068430.025
protein importGO:001703830.025
regulation of cytokine productionGO:000181730.025
transcription dna templatedGO:00063511810.025
regulation of protein modification by small protein conjugation or removalGO:190332030.025
positive regulation of protein complex assemblyGO:003133420.025
positive regulation of cell cycleGO:004578730.025
regulation of cellular metabolic processGO:00313233200.025
nucleocytoplasmic transportGO:000691340.024
cellular macromolecule biosynthetic processGO:00346452240.024
biosynthetic processGO:00090582940.024
response to stressGO:00069502630.024
regulation of rna metabolic processGO:00512522240.024
cellular aromatic compound metabolic processGO:00067252950.024
negative regulation of cellular processGO:00485232830.024
nucleic acid templated transcriptionGO:00976591810.024
regulation of nitrogen compound metabolic processGO:00511712510.024
protein acetylationGO:000647320.024
membrane fusionGO:006102520.024
mitochondrion organizationGO:000700540.023
regulation of cellular amino acid metabolic processGO:000652100.023
cellular response to extracellular stimulusGO:003166820.023
meiotic cell cycle processGO:190304630.023
rna biosynthetic processGO:00327741810.023
cellular ketone metabolic processGO:0042180110.023
cellular component disassemblyGO:002241110.023
organelle fusionGO:004828430.023
aromatic compound biosynthetic processGO:00194382170.023
regulation of cell shapeGO:000836010.023
autophagyGO:000691440.023
single organism membrane fusionGO:004480120.022
response to drugGO:004249330.022
heterocycle biosynthetic processGO:00181302150.022
cellular component movementGO:00069283350.022
regulation of cellular biosynthetic processGO:00313262450.022
regulation of meiotic cell cycleGO:005144510.022
single organism nuclear importGO:190259330.022
internal protein amino acid acetylationGO:000647520.022
organic cyclic compound biosynthetic processGO:19013622230.022
nucleobase containing compound biosynthetic processGO:00346542050.022
cell surface receptor signaling pathwayGO:00071663250.022
microtubule organizing center organizationGO:003102310.022
cellular component morphogenesisGO:00329893360.022
regulation of macromolecule biosynthetic processGO:00105562250.022
gtp metabolic processGO:004603940.022
regulation of nucleobase containing compound metabolic processGO:00192192500.021
cellular amino acid metabolic processGO:000652070.021
single organism metabolic processGO:00447102170.021
Yeast
alternative mrna splicing via spliceosomeGO:000038010.021
regulation of biosynthetic processGO:00098892500.021
regulation of alternative mrna splicing via spliceosomeGO:000038110.021
regulation of cell activationGO:005086510.021
endosomal transportGO:001619720.021
protein acylationGO:004354330.021
regulation of cellular ketone metabolic processGO:001056570.021
regulation of protein ubiquitinationGO:003139630.021
nuclear importGO:005117030.021
peptidyl lysine acetylationGO:001839420.021
internal peptidyl lysine acetylationGO:001839320.021
embryo development ending in birth or egg hatchingGO:00097922710.021
regulation of bindingGO:005109830.021
phagocytosis engulfmentGO:000691110.021
regulation of biological qualityGO:00650082630.021
oxoacid metabolic processGO:0043436310.021
regulation of rna biosynthetic processGO:20011412130.020
organelle organizationGO:00069962270.020
neuron differentiationGO:00301823530.020
ribonucleoside monophosphate catabolic processGO:000915840.020
protein metabolic processGO:00195381830.020
gtp catabolic processGO:000618420.020
locomotionGO:00400113130.020
guanosine containing compound catabolic processGO:190106920.020
guanosine containing compound metabolic processGO:190106840.020
stem cell proliferationGO:007208940.019
immune system processGO:00023762410.019
response to topologically incorrect proteinGO:003596620.019
protein targeting to nucleusGO:004474430.019
protein localization to plasma membraneGO:007265910.019
leukocyte proliferationGO:007066110.019
cell morphogenesisGO:00009022890.019
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.019
cognitionGO:005089010.019
positive regulation of cytokine productionGO:000181920.019
regulation of response to stimulusGO:00485832690.019
tissue remodelingGO:004877140.019
neuron developmentGO:00486662620.019
response to uvGO:000941130.019
protein import into nucleusGO:000660630.019
extrinsic apoptotic signaling pathwayGO:009719130.019
positive regulation of biological processGO:00485182530.019
regulation of multicellular organismal processGO:00512392770.019
regulation of cytoplasmic transportGO:190364940.019
single organism organelle organizationGO:19025891990.019
positive regulation of dna metabolic processGO:005105410.019
cellular response to starvationGO:000926710.019
rna localizationGO:000640340.018
establishment of localizationGO:00512342440.018
regulation of nucleic acid templated transcriptionGO:19035062130.018
regulation of intracellular protein transportGO:003315730.018
organic acid metabolic processGO:0006082310.018
positive regulation of cellular amine metabolic processGO:003324000.018
regulation of nucleocytoplasmic transportGO:004682220.018
cytoskeleton dependent cytokinesisGO:006164030.018
positive regulation of cell activationGO:005086710.018
protein complex disassemblyGO:004324110.018
nucleoside monophosphate catabolic processGO:000912540.018
cell part morphogenesisGO:00329902460.018
response to external stimulusGO:00096052640.018
protein polymerizationGO:005125840.018
cellular protein metabolic processGO:00442671290.018
cellular response to chemical stimulusGO:00708871570.018
regulation of protein localization to nucleusGO:190018020.018
organonitrogen compound metabolic processGO:1901564740.018
i kappab kinase nf kappab signalingGO:000724940.018
protein dephosphorylationGO:000647030.018
cell projection organizationGO:00300302840.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
regulation of transcription dna templatedGO:00063552130.017
regulation of signal transductionGO:00099662250.017
negative regulation of protein phosphorylationGO:000193340.017
macromolecular complex disassemblyGO:003298410.017
negative regulation of catabolic processGO:000989530.017
central nervous system developmentGO:00074173870.017
cell migrationGO:00164772370.017
protein secretionGO:000930610.017
regulation of signalingGO:00230512350.017
cell projection morphogenesisGO:00488582440.017
hemopoiesisGO:00300971830.017
mononuclear cell proliferationGO:003294310.017
g1 s transition of mitotic cell cycleGO:000008210.017
regulation of autophagyGO:001050630.017
cellular response to nutrient levelsGO:003166920.017
sensory organ developmentGO:00074233930.016
atp catabolic processGO:000620040.016
immune system developmentGO:00025201910.016
carboxylic acid metabolic processGO:0019752220.016
locomotor rhythmGO:004547530.016
small molecule metabolic processGO:0044281770.016
adult behaviorGO:003053420.016
cellular response to radiationGO:007147840.016
golgi vesicle transportGO:004819330.016
regulation of protein import into nucleusGO:004230620.016
cellular response to biotic stimulusGO:007121630.016
membrane invaginationGO:001032410.016
purine ribonucleoside monophosphate catabolic processGO:000916940.016
regulation of cell communicationGO:00106462320.016
exocytosisGO:000688710.016
nuclear exportGO:005116810.016
actin polymerization or depolymerizationGO:000815420.016
positive regulation of cell adhesionGO:004578510.016
regulation of developmental processGO:00507932470.016
regulation of protein targetingGO:190353320.016
regulation of purine nucleotide catabolic processGO:003312120.016
response to organic substanceGO:00100331530.016
regulation of synapse organizationGO:005080730.016
regulation of stem cell proliferationGO:007209120.016
macromolecule modificationGO:00434121110.016
purine nucleoside monophosphate catabolic processGO:000912840.016
cell substrate adhesionGO:003158940.016
cellular response to molecule of bacterial originGO:007121930.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
transportGO:00068102200.016
system processGO:00030081850.015
positive regulation of i kappab kinase nf kappab signalingGO:004312330.015
regulation of circadian rhythmGO:004275240.015
generation of neuronsGO:00486993850.015
regulation of nucleoside metabolic processGO:000911820.015
regulation of reproductive processGO:200024140.015
double strand break repairGO:000630230.015
cellular component assemblyGO:00226071700.015
regulation of nucleotide catabolic processGO:003081120.015
development of primary female sexual characteristicsGO:004654540.015
positive regulation of translationGO:004572710.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
negative regulation of sequestering of calcium ionGO:005128340.015
spermatid developmentGO:000728620.015
regulation of inflammatory responseGO:005072720.015
positive regulation of cytoskeleton organizationGO:005149530.015
neuroblast proliferationGO:000740520.015
eye developmentGO:00016542770.015
regulation of multicellular organismal developmentGO:20000262230.015
meiotic chromosome segregationGO:004513230.015
cellular respirationGO:004533330.015
Yeast
protein polyubiquitinationGO:000020940.015
cellular response to organic substanceGO:00713101050.015
negative regulation of kinase activityGO:003367340.015
sequestering of calcium ionGO:005120830.015
vasculature developmentGO:00019442780.015
cell motilityGO:00488702440.015
localization of cellGO:00516742440.015
regulation of cellular protein catabolic processGO:190336210.015
positive regulation of immune effector processGO:000269930.015
head developmentGO:00603223030.015
positive regulation of stress activated mapk cascadeGO:003287430.014
protein modification processGO:00362111000.014
positive regulation of secretionGO:005104710.014
regulation of neural precursor cell proliferationGO:200017730.014
regulation of protein polymerizationGO:003227120.014
erk1 and erk2 cascadeGO:007037140.014
growthGO:00400071740.014
cell cycle g1 s phase transitionGO:004484310.014
stem cell divisionGO:001714510.014
b cell activationGO:004211320.014
sequestering of metal ionGO:005123830.014
tube morphogenesisGO:00352393490.014
negative regulation of cellular catabolic processGO:003133030.014
cellular component biogenesisGO:00440851780.014
actin filament polymerizationGO:003004120.014
single organism localizationGO:19025782250.014
cell matrix adhesionGO:000716040.014
positive regulation of leukocyte differentiationGO:190210710.014
peptidyl serine phosphorylationGO:001810510.014
response to nutrientGO:000758430.014
homeostatic processGO:00425921420.014
synaptic growth at neuromuscular junctionGO:005112420.014
blood vessel developmentGO:00015682460.014
positive regulation of secretion by cellGO:190353210.014
regulation of gtpase activityGO:004308720.014
lymphocyte proliferationGO:004665110.014
morphogenesis of an epitheliumGO:00020093330.014
brain developmentGO:00074202930.014
cellular response to lipopolysaccharideGO:007122230.014
production of molecular mediator of immune responseGO:000244020.014
blood vessel morphogenesisGO:00485142160.014
regulation of synaptic plasticityGO:004816710.014
regulation of metal ion transportGO:001095940.014
positive regulation of cellular processGO:00485222010.013
fertilizationGO:000956630.013
centrosome organizationGO:005129710.013
secondary metabolic processGO:001974830.013
dna templated transcription elongationGO:000635430.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
heart developmentGO:00075073130.013
regulation of gtp catabolic processGO:003312420.013
primary neural tube formationGO:001402010.013
cellular protein modification processGO:00064641000.013
single fertilizationGO:000733830.013
regulation of synapse assemblyGO:005196330.013
developmental growthGO:00485891660.013
chemosensory behaviorGO:000763510.013
peptidyl serine modificationGO:001820920.013
embryonic organ developmentGO:00485683810.013
digestive system developmentGO:00551232890.013
protein stabilizationGO:005082120.013
female gonad developmentGO:000858540.013
negative regulation of nuclear divisionGO:005178430.013
regulation of blood pressureGO:000821710.013
macroautophagyGO:001623610.013
cellular carbohydrate metabolic processGO:004426240.013
female sex differentiationGO:004666040.013
positive regulation of map kinase activityGO:004340630.013
negative regulation of mapk cascadeGO:004340940.013
mitotic cytokinesisGO:000028130.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
cortical cytoskeleton organizationGO:003086510.013
negative regulation of cytokine productionGO:000181810.013
germ line stem cell maintenanceGO:003071820.013
chordate embryonic developmentGO:00430092710.013
cellular response to topologically incorrect proteinGO:003596720.013
establishment of protein localization to plasma membraneGO:009000210.013
regulation of erk1 and erk2 cascadeGO:007037240.013
nucleic acid transportGO:005065720.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
regulation of organelle assemblyGO:190211540.012
single organism transportGO:00447652060.012
compound eye developmentGO:004874920.012
somatic muscle developmentGO:000752540.012
regulation of jak stat cascadeGO:004642530.012
cell morphogenesis involved in differentiationGO:00009041950.012
spermatid differentiationGO:004851520.012
regulation of muscle contractionGO:000693730.012
positive regulation of nucleoside metabolic processGO:004597910.012
lipid catabolic processGO:001604240.012
protein homooligomerizationGO:005126030.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
olfactory lobe developmentGO:002198840.012
establishment of synaptic vesicle localizationGO:009748010.012
regulation of stem cell differentiationGO:200073640.012
regulation of production of molecular mediator of immune responseGO:000270010.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
cytosolic calcium ion transportGO:006040130.012
interspecies interaction between organismsGO:004441940.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
synaptic vesicle transportGO:004848910.012
angiogenesisGO:00015251580.012
activation of mapk activityGO:000018730.012
synaptic vesicle localizationGO:009747910.012
positive regulation of gtpase activityGO:004354710.012
deathGO:00162651210.012
cellular amide metabolic processGO:004360340.012
camera type eye developmentGO:00430102220.012
cortical actin cytoskeleton organizationGO:003086610.012
response to hydrogen peroxideGO:004254230.012
carbohydrate homeostasisGO:003350010.012
negative regulation of protein kinase activityGO:000646940.012
multi organism processGO:00517041340.012
cell deathGO:00082191210.011
somatic stem cell maintenanceGO:003501910.011
response to monosaccharideGO:003428430.011
g2 dna damage checkpointGO:003157230.011
calcium ion transport into cytosolGO:006040230.011
regulation of cell substrate adhesionGO:001081010.011
antimicrobial humoral responseGO:001973020.011
vacuolar transportGO:000703420.011
positive regulation of histone modificationGO:003105810.011
release of sequestered calcium ion into cytosolGO:005120930.011
apoptotic processGO:00069151160.011
post embryonic organ developmentGO:004856940.011
response to alkaloidGO:004327920.011
regulation of protein bindingGO:004339330.011
response to glucoseGO:000974930.011
intracellular signal transductionGO:0035556850.011
regulation of protein complex disassemblyGO:004324410.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
regulation of dna replicationGO:000627530.011
regulation of sequestering of calcium ionGO:005128240.011
negative regulation of defense responseGO:003134820.011
muscle structure developmentGO:00610611960.011
establishment of rna localizationGO:005123630.011
tube closureGO:006060610.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
response to hexoseGO:000974630.011
negative regulation of metabolic processGO:0009892860.011
transcription from rna polymerase ii promoterGO:0006366800.011
lamellipodium organizationGO:009758110.011
regulation of carbohydrate metabolic processGO:000610940.011
rna transportGO:005065820.011
lateral inhibitionGO:004633110.011
positive regulation of chromosome organizationGO:200125210.011
negative regulation of protein transportGO:005122430.011
mitotic dna integrity checkpointGO:004477440.011
cell substrate junction assemblyGO:000704420.011
regulation of cell projection assemblyGO:006049140.011
peptide transportGO:001583310.011
muscle cell differentiationGO:00426921390.011
histone h3 k4 methylationGO:005156820.011
signal transduction in absence of ligandGO:003803410.011
lamellipodium assemblyGO:003003210.011
transcription elongation from rna polymerase ii promoterGO:000636830.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
er to golgi vesicle mediated transportGO:000688810.011
carbohydrate biosynthetic processGO:001605110.011
cellular response to light stimulusGO:007148240.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
regionalizationGO:00030022740.011
positive regulation of protein polymerizationGO:003227320.011
regulation of anatomical structure morphogenesisGO:00226031300.011
viral processGO:001603210.011
positive regulation of metabolic processGO:00098931080.011
regulation of cell deathGO:00109411030.011
response to woundingGO:00096111160.011
positive regulation of nucleotide catabolic processGO:003081310.010
positive regulation of notch signaling pathwayGO:004574730.010
nucleobase containing compound transportGO:001593120.010
positive regulation of gtp catabolic processGO:003312610.010
glucose homeostasisGO:004259310.010
response to unfolded proteinGO:000698620.010
digestive tract developmentGO:00485652650.010
programmed cell deathGO:00125011190.010
positive regulation of myeloid cell differentiationGO:004563920.010
axonogenesisGO:00074091520.010
meiosis iGO:000712710.010
translational initiationGO:000641330.010
cell morphogenesis involved in neuron differentiationGO:00486671630.010
regulation of programmed cell deathGO:00430671010.010
neuron projection morphogenesisGO:00488121610.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
determination of bilateral symmetryGO:00098552040.010
response to biotic stimulusGO:0009607970.010
response to carbohydrateGO:000974330.010
multi organism cellular processGO:004476420.010
positive regulation of chromatin modificationGO:190331010.010
neuron projection developmentGO:00311751800.010
regulation of cellular carbohydrate metabolic processGO:001067540.010
response to abiotic stimulusGO:00096281220.010
entrainment of circadian clockGO:000964920.010
rna export from nucleusGO:000640510.010
regulation of cellular component organizationGO:0051128860.010
positive regulation of multi organism processGO:004390230.010
negative regulation of macromolecule metabolic processGO:0010605760.010
regulation of response to biotic stimulusGO:000283120.010
regulation of apoptotic processGO:0042981980.010
regulation of extrinsic apoptotic signaling pathwayGO:200123630.010
organism emergence from protective structureGO:007168440.010
gastrulationGO:00073692080.010
developmental programmed cell deathGO:001062340.010

ppa2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.046
nervous system diseaseDOID:86300.023
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
organ system cancerDOID:005068600.016
musculoskeletal system diseaseDOID:1700.016
disease of metabolismDOID:001466700.012
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.010