Danio rerio

0 known processes

sh3gl1b

SH3-domain GRB2-like 1b

(Aliases: sh3gl1,cb831)

sh3gl1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense responseGO:0006952470.764
cell morphogenesisGO:00009022890.709
neuron developmentGO:00486662620.683
system processGO:00030081850.641
generation of neuronsGO:00486993850.607
muscle tissue developmentGO:00605371100.586
locomotionGO:00400113130.579
positive regulation of biological processGO:00485182530.572
Worm
response to stressGO:00069502630.551
metal ion transportGO:0030001580.543
muscle structure developmentGO:00610611960.503
positive regulation of transportGO:005105020.488
cell morphogenesis involved in neuron differentiationGO:00486671630.479
neuron projection developmentGO:00311751800.440
cell projection organizationGO:00300302840.428
larval developmentGO:000216420.426
reactive oxygen species metabolic processGO:007259360.416
ion transportGO:00068111140.403
regulation of signalingGO:00230512350.403
cation transportGO:0006812810.386
multi organism processGO:00517041340.384
blood vessel morphogenesisGO:00485142160.380
Zebrafish
response to external stimulusGO:00096052640.379
cilium assemblyGO:0042384580.378
regulation of transportGO:0051049450.368
localization of cellGO:00516742440.347
negative regulation of cell communicationGO:0010648960.343
defense response to bacteriumGO:0042742220.317
regulation of response to stimulusGO:00485832690.309
regulation of immune system processGO:0002682340.303
cell morphogenesis involved in differentiationGO:00009041950.297
regulation of localizationGO:00328791040.292
cellular component morphogenesisGO:00329893360.286
regulation of cell communicationGO:00106462320.283
muscle cell differentiationGO:00426921390.275
single organism metabolic processGO:00447102170.261
cellular component movementGO:00069283350.259
establishment of localizationGO:00512342440.255
Worm Fly
vasculature developmentGO:00019442780.255
Zebrafish
axonal defasciculationGO:000741420.254
cellular component biogenesisGO:00440851780.250
synaptic growth at neuromuscular junctionGO:005112420.245
regulation of signal transductionGO:00099662250.244
transportGO:00068102200.241
Worm Fly
negative regulation of protein phosphorylationGO:000193340.241
convergent extension involved in gastrulationGO:0060027710.238
ion transmembrane transportGO:0034220910.233
cell projection morphogenesisGO:00488582440.227
angiogenesisGO:00015251580.220
axon developmentGO:00615641660.215
taxisGO:00423301090.212
monovalent inorganic cation transportGO:0015672420.209
regulation of metal ion transportGO:001095940.203
neuron projection morphogenesisGO:00488121610.200
regulation of cellular component organizationGO:0051128860.196
regulation of developmental processGO:00507932470.194
cell substrate adhesionGO:003158940.191
organonitrogen compound metabolic processGO:1901564740.191
response to chemicalGO:00422213200.188
cellular carbohydrate metabolic processGO:004426240.186
muscle organ developmentGO:00075171010.184
response to woundingGO:00096111160.182
regulation of reactive oxygen species metabolic processGO:200037720.178
regulation of biological qualityGO:00650082630.177
Fly
heterocycle metabolic processGO:00464832900.175
microtubule organizing center organizationGO:003102310.174
pathway restricted smad protein phosphorylationGO:006038910.174
cell surface receptor signaling pathwayGO:00071663250.174
neuron differentiationGO:00301823530.172
regulation of synaptic growth at neuromuscular junctionGO:000858210.168
cell substrate junction assemblyGO:000704420.167
cell matrix adhesionGO:000716040.166
peptidyl serine phosphorylationGO:001810510.166
regulation of biosynthetic processGO:00098892500.164
single organism transportGO:00447652060.163
Fly
organic substance biosynthetic processGO:19015762890.158
regulation of protein bindingGO:004339330.156
single organism biosynthetic processGO:0044711710.156
regulation of locomotionGO:0040012550.155
regulation of cellular amino acid metabolic processGO:000652100.155
regulation of synapse organizationGO:005080730.153
regulation of synapse assemblyGO:005196330.152
cell migrationGO:00164772370.152
heart morphogenesisGO:00030071560.152
defense response to gram negative bacteriumGO:005082980.151
cellular amine metabolic processGO:004410620.150
amine metabolic processGO:000930820.148
cellular component assemblyGO:00226071700.145
axon guidanceGO:0007411860.143
regulation of cell shapeGO:000836010.143
regulation of bindingGO:005109830.142
regulation of cell migrationGO:0030334400.142
cell motilityGO:00488702440.142
adherens junction organizationGO:003433240.142
response to other organismGO:0051707970.141
negative regulation of cellular processGO:00485232830.136
regulation of metabolic processGO:00192223590.135
single fertilizationGO:000733830.131
stem cell differentiationGO:00488631170.130
motor neuron axon guidanceGO:0008045230.130
hemopoiesisGO:00300971830.130
protein metabolic processGO:00195381830.129
circulatory system processGO:0003013870.126
cognitionGO:005089010.122
transmembrane transportGO:00550851200.121
cell part morphogenesisGO:00329902460.121
fertilizationGO:000956630.119
multicellular organism reproductionGO:0032504350.119
regulation of cellular amine metabolic processGO:003323800.117
striated muscle cell developmentGO:00550021080.116
regulation of anatomical structure sizeGO:0090066330.114
cell adhesionGO:0007155400.113
cellular response to chemical stimulusGO:00708871570.111
positive regulation of immune responseGO:0050778110.110
regulation of cytokine productionGO:000181730.108
positive regulation of cellular amino acid metabolic processGO:004576400.108
regulation of nitrogen compound metabolic processGO:00511712510.107
extrinsic apoptotic signaling pathwayGO:009719130.105
regulation of cellular ketone metabolic processGO:001056570.104
negative regulation of metabolic processGO:0009892860.101
regulation of ion transportGO:0043269220.101
stem cell maintenanceGO:001982740.100
striated muscle tissue developmentGO:00147061100.098
digestive tract morphogenesisGO:00485462310.097
negative regulation of protein kinase activityGO:000646940.097
immune system processGO:00023762410.095
regulation of cell adhesionGO:0030155150.094
single organism localizationGO:19025782250.094
Fly
regulation of cellular component sizeGO:0032535300.094
cellular response to external stimulusGO:007149620.093
response to organic cyclic compoundGO:0014070510.093
establishment of localization in cellGO:0051649770.093
Fly
nitrogen compound metabolic processGO:00068073190.092
cellular response to endogenous stimulusGO:0071495680.092
membrane invaginationGO:001032410.092
regulation of macromolecule metabolic processGO:00602553170.091
cellular amino acid metabolic processGO:000652070.091
cellular response to nutrient levelsGO:003166920.090
negative regulation of phosphate metabolic processGO:0045936130.089
heart developmentGO:00075073130.088
regulation of cellular biosynthetic processGO:00313262450.088
homeostatic processGO:00425921420.088
cellular macromolecule metabolic processGO:00442603910.087
cellular response to hormone stimulusGO:0032870390.087
response to nitrogen compoundGO:1901698190.086
cilium morphogenesisGO:0060271850.083
regulation of cellular carbohydrate metabolic processGO:001067540.082
actin polymerization or depolymerizationGO:000815420.082
specification of symmetryGO:00097992040.081
muscle cell developmentGO:00550011150.081
response to organic substanceGO:00100331530.081
striated muscle cell differentiationGO:00511461290.080
response to biotic stimulusGO:0009607970.079
axonogenesisGO:00074091520.078
anterior posterior pattern specificationGO:00099521520.077
lateral inhibitionGO:004633110.077
negative regulation of signalingGO:0023057960.077
basement membrane organizationGO:007171150.076
synaptic vesicle transportGO:004848910.076
Fly
regulation of gene expressionGO:00104682650.076
nucleic acid templated transcriptionGO:00976591810.075
cellular component assembly involved in morphogenesisGO:00109271070.074
signal transductionGO:00071654550.074
protein polymerizationGO:005125840.074
single organismal cell cell adhesionGO:0016337290.073
single organism cell adhesionGO:0098602290.073
carbohydrate homeostasisGO:003350010.072
regulation of peptidyl tyrosine phosphorylationGO:005073010.072
small molecule metabolic processGO:0044281770.072
detection of stimulus involved in sensory perceptionGO:0050906210.072
multicellular organism growthGO:003526440.071
defense response to other organismGO:0098542330.070
oxoacid metabolic processGO:0043436310.070
carbohydrate biosynthetic processGO:001605110.070
regulation of nucleocytoplasmic transportGO:004682220.069
regulation of transcription dna templatedGO:00063552130.069
phosphate containing compound metabolic processGO:00067961080.069
organelle organizationGO:00069962270.068
sprouting angiogenesisGO:0002040530.068
negative regulation of macromolecule metabolic processGO:0010605760.067
regulation of autophagyGO:001050630.067
regulation of innate immune responseGO:0045088110.067
positive regulation of developmental processGO:0051094500.066
positive regulation of cellular metabolic processGO:0031325940.066
stem cell developmentGO:0048864820.065
regulation of immune responseGO:0050776140.064
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.064
gene expressionGO:00104672520.063
sensory perception of smellGO:000760820.063
positive regulation of cellular amine metabolic processGO:003324000.063
synaptic target recognitionGO:000803910.062
macromolecular complex subunit organizationGO:0043933740.062
response to external biotic stimulusGO:0043207970.062
agingGO:000756820.062
regulation of protein import into nucleusGO:004230620.061
macromolecule modificationGO:00434121110.061
synapse organizationGO:0050808210.060
regulation of heart growthGO:006042020.060
sensory perception of chemical stimulusGO:000760630.060
cellular nitrogen compound metabolic processGO:00346412900.060
cellular nitrogen compound biosynthetic processGO:00442712180.060
central nervous system developmentGO:00074173870.060
positive regulation of cellular component biogenesisGO:004408930.059
regulation of protein complex assemblyGO:004325430.059
multi organism reproductive processGO:0044703360.059
blood vessel developmentGO:00015682460.059
Zebrafish
regulation of cytoplasmic transportGO:190364940.059
negative regulation of response to stimulusGO:00485851040.058
single organism organelle organizationGO:19025891990.058
phagocytosis engulfmentGO:000691110.058
gastrulationGO:00073692080.058
peptidyl serine modificationGO:001820920.057
multicellular organismal reproductive processGO:0048609350.057
response to mechanical stimulusGO:0009612240.057
energy homeostasisGO:009700930.057
g protein coupled receptor signaling pathwayGO:0007186740.056
negative regulation of developmental growthGO:004864090.056
regulation of wnt signaling pathway planar cell polarity pathwayGO:200009520.056
regulation of cell projection organizationGO:0031344440.056
establishment of vesicle localizationGO:0051650240.056
Fly
protein targeting to nucleusGO:004474430.056
immune responseGO:0006955280.056
negative regulation of synapse assemblyGO:005196420.056
detection of abiotic stimulusGO:0009582240.055
astrocyte differentiationGO:004870810.055
positive regulation of secretion by cellGO:190353210.054
regulation of cellular macromolecule biosynthetic processGO:20001122220.054
regulation of cell projection assemblyGO:006049140.054
regulation of defense responseGO:0031347140.054
detection of stimulusGO:0051606290.054
regulation of response to external stimulusGO:0032101310.054
cell growthGO:0016049570.053
nucleobase containing compound biosynthetic processGO:00346542050.053
regulation of dna replicationGO:000627530.053
regulation of establishment of protein localizationGO:007020140.053
nucleocytoplasmic transportGO:000691340.053
positive regulation of cell adhesionGO:004578510.053
intracellular signal transductionGO:0035556850.052
chondrocyte developmentGO:000206340.051
biological adhesionGO:0022610400.051
positive regulation of cellular processGO:00485222010.051
Worm
cardiac muscle tissue developmentGO:0048738480.051
enzyme linked receptor protein signaling pathwayGO:00071671060.050
negative regulation of signal transductionGO:0009968940.050
blood circulationGO:0008015870.050
cortical cytoskeleton organizationGO:003086510.049
positive regulation of secretionGO:005104710.049
regulation of cytokine mediated signaling pathwayGO:000195930.049
cellular ketone metabolic processGO:0042180110.049
muscle organ morphogenesisGO:004864480.049
synaptic vesicle localizationGO:009747910.048
Fly
innate immune responseGO:0045087130.048
regulation of multicellular organismal processGO:00512392770.048
organonitrogen compound biosynthetic processGO:1901566470.047
regulation of cellular metabolic processGO:00313233200.047
behaviorGO:0007610740.047
negative regulation of epithelial cell proliferationGO:005068010.047
cellular response to growth factor stimulusGO:0071363390.046
regulation of cell motilityGO:2000145460.046
protein complex subunit organizationGO:0071822460.046
regulation of neuron projection developmentGO:0010975400.046
biosynthetic processGO:00090582940.046
regulation of synapse structure and activityGO:005080350.046
Fly
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.045
regulation of apoptotic processGO:0042981980.045
organic cyclic compound metabolic processGO:19013603010.045
cellular response to nitrogen compoundGO:190169960.045
regulation of nervous system developmentGO:0051960900.045
response to bacteriumGO:0009617580.045
organelle assemblyGO:00709251100.044
response to antibioticGO:004667710.044
protein import into nucleusGO:000660630.044
regulation of programmed cell deathGO:00430671010.044
cell projection assemblyGO:0030031640.044
regulation of cell differentiationGO:00455951420.043
reactive oxygen species biosynthetic processGO:190340910.043
neuron projection guidanceGO:0097485860.043
negative regulation of catalytic activityGO:0043086210.043
carbohydrate derivative metabolic processGO:1901135610.043
regulation of response to cytokine stimulusGO:006075930.043
nuclear importGO:005117030.043
regulation of bone mineralizationGO:003050020.043
regulation of cellular component movementGO:0051270550.043
protein modification processGO:00362111000.042
immune response regulating signaling pathwayGO:000276450.042
rna biosynthetic processGO:00327741810.042
erk1 and erk2 cascadeGO:007037140.042
response to oxygen containing compoundGO:1901700550.042
negative regulation of dna metabolic processGO:005105340.041
determination of bilateral symmetryGO:00098552040.041
centrosome organizationGO:005129710.041
actin filament organizationGO:0007015150.041
synaptic vesicle recyclingGO:003646510.041
Fly
regulation of cytoskeleton organizationGO:0051493110.041
positive regulation of cell cycleGO:004578730.040
cellular protein modification processGO:00064641000.040
protein localization to nucleusGO:003450430.040
negative regulation of dna replicationGO:000815620.040
response to cortisolGO:005141410.040
extracellular structure organizationGO:0043062270.040
cellular response to extracellular stimulusGO:003166820.039
muscle system processGO:0003012200.039
glucose homeostasisGO:004259310.039
guanosine containing compound metabolic processGO:190106840.039
regulation of protein metabolic processGO:0051246560.039
protein complex assemblyGO:0006461300.038
sodium ion transportGO:0006814240.038
mucopolysaccharide metabolic processGO:190351020.038
digestive tract developmentGO:00485652650.038
regulation of inflammatory responseGO:005072720.038
regulation of cell proliferationGO:0042127370.038
epithelial cell morphogenesisGO:000338220.038
neuromuscular junction developmentGO:000752890.038
regulation of developmental growthGO:0048638380.038
coagulationGO:0050817130.038
regulation of nucleobase containing compound metabolic processGO:00192192500.038
regulation of multicellular organismal metabolic processGO:004424620.038
response to abiotic stimulusGO:00096281220.037
syncytium formation by plasma membrane fusionGO:0000768120.037
negative regulation of biological processGO:00485193040.037
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.037
cation transmembrane transportGO:0098655650.037
macromolecule biosynthetic processGO:00090592270.036
regulation of intracellular protein transportGO:003315730.036
heterocycle biosynthetic processGO:00181302150.036
regulation of carbohydrate metabolic processGO:000610940.035
digestive system developmentGO:00551232890.035
actin filament bundle assemblyGO:005101760.035
regulation of cell sizeGO:0008361290.035
negative regulation of mapk cascadeGO:004340940.035
phosphorus metabolic processGO:00067931090.035
organic cyclic compound biosynthetic processGO:19013622230.035
glucose importGO:004632320.034
response to growth factorGO:0070848390.034
nucleobase containing compound metabolic processGO:00061392740.034
single organism behaviorGO:0044708240.034
multicellular organismal metabolic processGO:004423620.034
sensory perceptionGO:0007600390.034
deathGO:00162651210.034
Worm
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.034
cell cycle g2 m phase transitionGO:004483940.034
inorganic ion transmembrane transportGO:0098660570.034
negative regulation of locomotionGO:0040013180.034
positive regulation of erk1 and erk2 cascadeGO:007037420.033
activation of mapk activityGO:000018730.033
regulation of multicellular organismal developmentGO:20000262230.033
cartilage developmentGO:0051216960.033
regulation of sodium ion transportGO:000202820.033
sarcomere organizationGO:0045214260.033
regulation of multicellular organism growthGO:004001440.033
positive regulation of signalingGO:0023056560.033
cellular response to organic substanceGO:00713101050.032
regulation of rna biosynthetic processGO:20011412130.032
response to hormoneGO:0009725480.032
developmental growthGO:00485891660.032
negative regulation of response to cytokine stimulusGO:006076120.032
response to axon injuryGO:0048678140.032
internal peptidyl lysine acetylationGO:001839320.032
negative regulation of cell migrationGO:0030336170.032
regulation of epithelial cell proliferationGO:005067830.032
actin filament polymerizationGO:003004120.031
peptide transportGO:001583310.031
nuclear transportGO:005116940.031
synapse assemblyGO:000741690.031
regulation of intracellular signal transductionGO:1902531570.031
lamellipodium organizationGO:009758110.031
cytokine mediated signaling pathwayGO:001922170.031
regulation of cell developmentGO:00602841000.031
positive regulation of cell differentiationGO:0045597300.031
regulation of tyrosine phosphorylation of stat proteinGO:004250910.030
autophagyGO:000691440.030
regulation of protein transportGO:005122330.030
synaptic transmissionGO:0007268350.030
Fly
radial glial cell differentiationGO:006001920.030
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.030
regulation of growthGO:0040008420.030
cellular response to starvationGO:000926710.030
cellular biosynthetic processGO:00442492860.030
positive regulation of multicellular organismal processGO:0051240520.030
regulation of production of molecular mediator of immune responseGO:000270010.030
regulation of behaviorGO:0050795240.030
muscle fiber developmentGO:0048747520.030
regulation of protein polymerizationGO:003227120.029
phagocytosisGO:000690930.029
peptidyl threonine phosphorylationGO:001810710.029
nucleic acid metabolic processGO:00903042440.029
positive regulation of apoptotic processGO:0043065290.029
muscle contractionGO:0006936180.029
response to fluid shear stressGO:003440520.029
germ line stem cell maintenanceGO:003071820.029
cardiac muscle cell developmentGO:0055013200.029
ovulation cycle processGO:002260220.029
protein complex biogenesisGO:0070271300.029
negative regulation of kinase activityGO:003367340.029
immune system developmentGO:00025201910.029
regulation of nucleoside metabolic processGO:000911820.028
regulation of cardiac muscle tissue developmentGO:005502410.028
regulation of calcium ion transportGO:005192420.028
cardiac cell developmentGO:0055006210.028
localization within membraneGO:005166810.028
regulation of meiotic cell cycleGO:005144510.028
protein complex disassemblyGO:004324110.028
programmed cell deathGO:00125011190.028
developmental process involved in reproductionGO:0003006270.028
regulation of protein ubiquitinationGO:003139630.028
transcription dna templatedGO:00063511810.028
positive regulation of apoptotic signaling pathwayGO:200123510.027
extracellular matrix organizationGO:0030198270.027
positive regulation of striated muscle tissue developmentGO:004584410.027
negative regulation of phosphorus metabolic processGO:0010563130.027
myotube differentiationGO:0014902450.027
optic placode formation involved in camera type eye formationGO:004661930.027
modification dependent macromolecule catabolic processGO:004363230.027
regulation of posttranscriptional gene silencingGO:006014710.027
regulation of transmembrane transportGO:0034762180.027
oocyte maturationGO:000155640.027
extracellular matrix assemblyGO:008502910.027
regulation of neuron differentiationGO:0045664560.027
single organism nuclear importGO:190259330.027
positive regulation of cell activationGO:005086710.027
activation of immune responseGO:000225390.026
myoblast fusionGO:0007520100.026
neuron projection regenerationGO:0031102160.026
cytoskeleton organizationGO:0007010960.026
protein dephosphorylationGO:000647030.026
heart rudiment developmentGO:000331380.026
regulation of receptor activityGO:001046920.026
pole plasm assemblyGO:000731540.026
regulation of macromolecule biosynthetic processGO:00105562250.026
production of molecular mediator of immune responseGO:000244020.026
cellular response to oxygen containing compoundGO:1901701200.026
aromatic compound biosynthetic processGO:00194382170.026
regulation of organelle organizationGO:0033043290.026
nuclear migrationGO:000709730.025
regulation of primary metabolic processGO:00800903110.025
regulation of axonogenesisGO:0050770320.025
estrogen metabolic processGO:000821020.025
tube morphogenesisGO:00352393490.025
actin filament bundle organizationGO:006157260.025
phosphorylationGO:0016310690.025
positive regulation of small gtpase mediated signal transductionGO:005105710.025
organic acid metabolic processGO:0006082310.025
regulation of cell cycleGO:0051726520.025
negative regulation of cytokine mediated signaling pathwayGO:000196020.025
neurotransmitter secretionGO:000726920.024
detection of external stimulusGO:0009581240.024
positive regulation of defense responseGO:003134990.024
response to lipidGO:0033993600.024
protein acetylationGO:000647320.024
vesicle mediated transportGO:0016192220.024
Worm Fly
regulation of cell morphogenesisGO:0022604420.024
reproductive processGO:0022414400.024
vesicle localizationGO:0051648270.024
Fly
regulation of molecular functionGO:0065009700.024
regulation of cell morphogenesis involved in differentiationGO:0010769380.024
regulation of cellular protein metabolic processGO:0032268520.023
cell cycle g1 s phase transitionGO:004484310.023
muscle tissue morphogenesisGO:006041570.023
hematopoietic or lymphoid organ developmentGO:00485341910.023
inorganic cation transmembrane transportGO:0098662500.023
female gonad developmentGO:000858540.023
antimicrobial humoral responseGO:001973020.023
cell migration involved in gastrulationGO:0042074790.023
regulation of ion transmembrane transportGO:0034765180.023
heart processGO:0003015710.023
cytokinesisGO:000091030.023
neurotransmitter transportGO:000683620.023
gamete generationGO:0007276330.023
positive regulation of muscle organ developmentGO:004863610.023
response to virusGO:0009615210.022
positive regulation of programmed cell deathGO:0043068290.022
lamellipodium assemblyGO:003003210.022
protein importGO:001703830.022
cellular response to stressGO:0033554620.022
apoptotic processGO:00069151160.022
regulation of response to stressGO:0080134360.022
mitochondrion organizationGO:000700540.022
positive regulation of map kinase activityGO:004340630.022

sh3gl1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.243
musculoskeletal system diseaseDOID:1700.169
cardiovascular system diseaseDOID:128700.112
myopathyDOID:42300.095
muscular diseaseDOID:008000000.095
intrinsic cardiomyopathyDOID:006003600.095
cardiomyopathyDOID:005070000.095
heart diseaseDOID:11400.095
muscle tissue diseaseDOID:6600.095
nervous system diseaseDOID:86300.032
inherited metabolic disorderDOID:65500.027
disease of metabolismDOID:001466700.027
bone diseaseDOID:008000100.025
dysostosisDOID:193400.025
connective tissue diseaseDOID:6500.025
synostosisDOID:1197100.025
bone development diseaseDOID:008000600.025