Danio rerio

58 known processes

rpgrb

retinitis pigmentosa GTPase regulator b

rpgrb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
renal system developmentGO:0072001940.183
specification of symmetryGO:00097992040.164
urogenital system developmentGO:0001655970.153
heart developmentGO:00075073130.147
embryonic organ developmentGO:00485683810.131
positive regulation of biological processGO:00485182530.130
eye developmentGO:00016542770.116
morphogenesis of an epitheliumGO:00020093330.115
embryonic organ morphogenesisGO:00485622740.113
sensory organ developmentGO:00074233930.107
tube morphogenesisGO:00352393490.097
signal transductionGO:00071654550.097
heart loopingGO:0001947940.089
cellular biosynthetic processGO:00442492860.086
determination of left right symmetryGO:00073681790.086
somitogenesisGO:0001756870.084
organic substance biosynthetic processGO:19015762890.083
positive regulation of transportGO:005105020.072
muscle cell developmentGO:00550011150.067
determination of heart left right asymmetryGO:00613711170.067
regulation of signalingGO:00230512350.067
embryonic heart tube morphogenesisGO:00031431080.065
camera type eye developmentGO:00430102220.065
response to chemicalGO:00422213200.064
determination of bilateral symmetryGO:00098552040.063
striated muscle cell developmentGO:00550021080.062
lipid storageGO:001991510.061
regulation of synapse organizationGO:005080730.060
chordate embryonic developmentGO:00430092710.060
regulation of establishment of protein localizationGO:007020140.060
generation of neuronsGO:00486993850.058
biosynthetic processGO:00090582940.056
skeletal system developmentGO:00015011810.055
agingGO:000756820.054
negative regulation of cellular processGO:00485232830.052
retina development in camera type eyeGO:00600411460.051
maintenance of locationGO:005123540.051
inner ear developmentGO:00488391260.051
rna biosynthetic processGO:00327741810.050
brain developmentGO:00074202930.050
regulation of macromolecule metabolic processGO:00602553170.050
muscle cell differentiationGO:00426921390.049
regulation of response to stimulusGO:00485832690.048
regulation of primary metabolic processGO:00800903110.047
nucleocytoplasmic transportGO:000691340.047
regulation of metabolic processGO:00192223590.046
striated muscle tissue developmentGO:00147061100.046
camera type eye morphogenesisGO:00485931080.045
regulation of multicellular organismal processGO:00512392770.044
epithelial tube morphogenesisGO:00605621480.043
nucleobase containing compound metabolic processGO:00061392740.043
heterocycle metabolic processGO:00464832900.043
muscle tissue developmentGO:00605371100.043
regulation of macromolecule biosynthetic processGO:00105562250.042
regulation of cellular metabolic processGO:00313233200.042
macromolecule biosynthetic processGO:00090592270.041
multicellular organism growthGO:003526440.041
nitrogen compound metabolic processGO:00068073190.041
regionalizationGO:00030022740.040
regulation of cell communicationGO:00106462320.040
protein localization to nucleusGO:003450430.040
neuron differentiationGO:00301823530.040
cellular nitrogen compound metabolic processGO:00346412900.039
embryonic heart tube developmentGO:00350501330.039
positive regulation of catabolic processGO:000989640.039
organic cyclic compound biosynthetic processGO:19013622230.038
cellular macromolecule metabolic processGO:00442603910.038
negative regulation of biological processGO:00485193040.037
appendage morphogenesisGO:0035107560.037
pronephros developmentGO:0048793690.037
single organism metabolic processGO:00447102170.037
regulation of protein transportGO:005122330.035
photoreceptor cell differentiationGO:0046530550.035
rna metabolic processGO:00160702190.035
regulation of apoptotic processGO:0042981980.034
striated muscle cell differentiationGO:00511461290.034
central nervous system developmentGO:00074173870.034
muscle structure developmentGO:00610611960.034
blood vessel developmentGO:00015682460.033
neuron developmentGO:00486662620.031
response to carbohydrateGO:000974330.030
amine metabolic processGO:000930820.030
stem cell maintenanceGO:001982740.029
nuclear importGO:005117030.029
regulation of cellular amine metabolic processGO:003323800.029
organic cyclic compound metabolic processGO:19013603010.029
cellular response to external stimulusGO:007149620.029
regulation of protein targetingGO:190353320.029
larval developmentGO:000216420.028
nucleic acid metabolic processGO:00903042440.028
vasculature developmentGO:00019442780.028
heart morphogenesisGO:00030071560.028
fat soluble vitamin metabolic processGO:000677540.027
regulation of cell deathGO:00109411030.027
response to stressGO:00069502630.027
cellular amine metabolic processGO:004410620.027
cellular protein catabolic processGO:004425740.027
cellular component assemblyGO:00226071700.027
regulation of cytoplasmic transportGO:190364940.027
developmental growthGO:00485891660.027
regulation of signal transductionGO:00099662250.027
fin developmentGO:0033333770.027
regulation of biosynthetic processGO:00098892500.026
protein targeting to nucleusGO:004474430.026
regulation of multicellular organismal developmentGO:20000262230.026
ear developmentGO:00435831270.026
positive regulation of cellular catabolic processGO:003133130.026
regulation of protein complex assemblyGO:004325430.026
cellular modified amino acid metabolic processGO:000657530.026
cell matrix adhesionGO:000716040.025
positive regulation of cellular component biogenesisGO:004408930.025
digestive tract morphogenesisGO:00485462310.025
regulation of muscle contractionGO:000693730.025
regulation of nucleocytoplasmic transportGO:004682220.025
modification dependent macromolecule catabolic processGO:004363230.025
adult behaviorGO:003053420.025
exocytosisGO:000688710.025
mitochondrion organizationGO:000700540.025
nuclear transportGO:005116940.025
ear morphogenesisGO:0042471640.025
cellular aromatic compound metabolic processGO:00067252950.025
single organism nuclear importGO:190259330.025
protein metabolic processGO:00195381830.025
regulation of reproductive processGO:200024140.024
eye photoreceptor cell differentiationGO:0001754450.024
response to vitaminGO:003327330.024
regulation of developmental processGO:00507932470.024
somite developmentGO:0061053960.024
modification dependent protein catabolic processGO:001994130.024
nucleobase containing compound biosynthetic processGO:00346542050.024
regulation of nitrogen compound metabolic processGO:00511712510.024
regulation of protein localization to nucleusGO:190018020.024
oocyte maturationGO:000155640.024
heterocycle biosynthetic processGO:00181302150.023
protein import into nucleusGO:000660630.023
regulation of protein import into nucleusGO:004230620.023
deathGO:00162651210.023
cognitionGO:005089010.023
cell substrate adhesionGO:003158940.023
gene expressionGO:00104672520.023
establishment of localizationGO:00512342440.023
Mouse
cellular macromolecule biosynthetic processGO:00346452240.022
negative regulation of protein phosphorylationGO:000193340.022
cell projection organizationGO:00300302840.022
regulation of cellular biosynthetic processGO:00313262450.022
nucleic acid templated transcriptionGO:00976591810.022
transcription from rna polymerase ii promoterGO:0006366800.022
regulation of multicellular organism growthGO:004001440.022
nucleoside monophosphate catabolic processGO:000912540.021
digestive system developmentGO:00551232890.021
regulation of nucleic acid templated transcriptionGO:19035062130.021
proteasomal protein catabolic processGO:001049820.021
cellular component biogenesisGO:00440851780.021
cell deathGO:00082191210.021
response to external stimulusGO:00096052640.021
positive regulation of secretion by cellGO:190353210.020
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
appendage developmentGO:0048736800.020
regulation of rna metabolic processGO:00512522240.020
adherens junction organizationGO:003433240.020
sensory organ morphogenesisGO:00905962000.020
regulation of gene expressionGO:00104682650.020
proteolysis involved in cellular protein catabolic processGO:005160330.020
aromatic compound biosynthetic processGO:00194382170.020
cell part morphogenesisGO:00329902460.020
ubiquitin dependent protein catabolic processGO:000651130.020
anterior posterior pattern specificationGO:00099521520.020
protein importGO:001703830.020
locomotionGO:00400113130.019
head developmentGO:00603223030.019
retina morphogenesis in camera type eyeGO:0060042790.019
ribonucleoside monophosphate catabolic processGO:000915840.019
stem cell developmentGO:0048864820.019
purine ribonucleoside monophosphate catabolic processGO:000916940.019
regulation of cell developmentGO:00602841000.018
regulation of programmed cell deathGO:00430671010.018
extrinsic apoptotic signaling pathwayGO:009719130.018
alternative mrna splicing via spliceosomeGO:000038010.018
oxoacid metabolic processGO:0043436310.018
meiotic nuclear divisionGO:000712640.018
regulation of cellular macromolecule biosynthetic processGO:20001122220.018
regulation of synaptic plasticityGO:004816710.018
xenobiotic metabolic processGO:000680540.018
regulation of cellular amino acid metabolic processGO:000652100.018
positive regulation of nucleoside metabolic processGO:004597910.017
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.017
cell surface receptor signaling pathwayGO:00071663250.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
synaptic growth at neuromuscular junctionGO:005112420.017
embryonic skeletal system developmentGO:0048706970.017
muscle organ developmentGO:00075171010.017
water homeostasisGO:003010440.017
protein glycosylationGO:000648690.017
cellular localizationGO:0051641970.017
Mouse
cellular response to extracellular stimulusGO:003166820.017
positive regulation of secretionGO:005104710.017
regulation of synapse assemblyGO:005196330.017
regulation of transmembrane transporter activityGO:002289820.017
positive regulation of metabolic processGO:00098931080.017
interspecies interaction between organismsGO:004441940.017
germ line stem cell maintenanceGO:003071820.017
negative regulation of macromolecule metabolic processGO:0010605760.017
negative regulation of cellular catabolic processGO:003133030.017
response to nutrientGO:000758430.017
regulation of cellular ketone metabolic processGO:001056570.017
negative regulation of nucleocytoplasmic transportGO:004682320.017
programmed cell deathGO:00125011190.016
negative regulation of cytoplasmic transportGO:190365020.016
rna localizationGO:000640340.016
pigmentationGO:0043473850.016
negative regulation of protein kinase activityGO:000646940.016
regulation of protein catabolic processGO:004217610.016
positive regulation of cellular amine metabolic processGO:003324000.016
positive regulation of cellular metabolic processGO:0031325940.016
positive regulation of cytokine productionGO:000181920.016
vitamin metabolic processGO:0006766110.016
regulation of metal ion transportGO:001095940.016
regulation of neural precursor cell proliferationGO:200017730.016
cellular component movementGO:00069283350.016
regulation of organelle assemblyGO:190211540.016
organonitrogen compound metabolic processGO:1901564740.016
inner ear morphogenesisGO:0042472630.016
small molecule metabolic processGO:0044281770.016
regulation of cellular protein catabolic processGO:190336210.016
response to glucoseGO:000974930.016
membrane hyperpolarizationGO:006008110.016
cellular ketone metabolic processGO:0042180110.016
toll like receptor signaling pathwayGO:000222440.016
embryo development ending in birth or egg hatchingGO:00097922710.016
epithelial cell differentiationGO:00308551160.015
response to vitamin b3GO:003355220.015
regulation of photoreceptor cell differentiationGO:004653220.015
embryonic limb morphogenesisGO:003032620.015
neuron projection developmentGO:00311751800.015
segmentationGO:0035282970.015
cell migrationGO:00164772370.015
regulation of nucleobase containing compound metabolic processGO:00192192500.015
regulation of response to cytokine stimulusGO:006075930.015
immune system processGO:00023762410.015
regulation of cell differentiationGO:00455951420.015
erk1 and erk2 cascadeGO:007037140.015
apoptotic processGO:00069151160.015
negative regulation of intracellular transportGO:003238730.015
regulation of nervous system developmentGO:0051960900.015
positive regulation of neural precursor cell proliferationGO:200017910.015
regulation of oocyte developmentGO:006028130.015
meiotic cell cycle processGO:190304630.015
neural crest cell developmentGO:0014032620.015
regulation of nucleotide catabolic processGO:003081120.015
regulation of epithelial cell proliferationGO:005067830.015
negative regulation of kinase activityGO:003367340.015
regulation of mrna splicing via spliceosomeGO:004802430.015
carboxylic acid metabolic processGO:0019752220.015
septum transversum developmentGO:000334340.015
positive regulation of nucleotide catabolic processGO:003081310.015
establishment of synaptic vesicle localizationGO:009748010.015
regulation of transporter activityGO:003240920.014
regulation of erk1 and erk2 cascadeGO:007037240.014
stem cell proliferationGO:007208940.014
regulation of hormone secretionGO:004688320.014
protein homooligomerizationGO:005126030.014
atp catabolic processGO:000620040.014
regulation of dendrite developmentGO:005077330.014
negative regulation of protein transportGO:005122430.014
cellular response to nutrient levelsGO:003166920.014
stem cell differentiationGO:00488631170.014
negative regulation of catabolic processGO:000989530.014
nerve developmentGO:0021675450.014
phagocytosisGO:000690930.014
positive regulation of dna metabolic processGO:005105410.014
regulation of nucleoside metabolic processGO:000911820.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
establishment of localization in cellGO:0051649770.014
Mouse
cellular response to starvationGO:000926710.014
neural crest cell differentiationGO:0014033720.014
peptide transportGO:001583310.014
protein complex localizationGO:003150310.014
regulation of neurogenesisGO:0050767870.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
insulin like growth factor receptor signaling pathwayGO:004800940.014
guanosine containing compound catabolic processGO:190106920.013
negative regulation of signal transductionGO:0009968940.013
cell migration involved in gastrulationGO:0042074790.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
negative regulation of intracellular protein transportGO:009031730.013
localization of cellGO:00516742440.013
carbohydrate homeostasisGO:003350010.013
response to monosaccharideGO:003428430.013
hemopoiesisGO:00300971830.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
establishment of protein localization to organelleGO:007259440.013
developmental pigmentationGO:0048066480.013
cellular protein metabolic processGO:00442671290.013
negative regulation of oocyte developmentGO:006028320.013
cellular component assembly involved in morphogenesisGO:00109271070.013
gland developmentGO:00487321430.013
kidney developmentGO:0001822920.013
system processGO:00030081850.013
Mouse
epidermis developmentGO:0008544480.013
macromolecular complex assemblyGO:0065003350.013
muscle fiber developmentGO:0048747520.013
cell morphogenesis involved in differentiationGO:00009041950.013
centrosome organizationGO:005129710.013
regulation of anatomical structure morphogenesisGO:00226031300.013
cardiac muscle tissue developmentGO:0048738480.013
behaviorGO:0007610740.013
regulation of blood circulationGO:1903522320.012
immune system developmentGO:00025201910.012
lipid catabolic processGO:001604240.012
secondary metabolic processGO:001974830.012
b cell activationGO:004211320.012
embryonic cranial skeleton morphogenesisGO:0048701900.012
photoreceptor cell developmentGO:0042461400.012
small molecule catabolic processGO:004428230.012
regulation of alternative mrna splicing via spliceosomeGO:000038110.012
transcription dna templatedGO:00063511810.012
regulation of ion transmembrane transporter activityGO:003241220.012
connective tissue developmentGO:0061448990.012
response to corticosteroidGO:003196010.012
gastrulationGO:00073692080.012
protein secretionGO:000930610.012
regulation of tube sizeGO:003515020.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
membrane invaginationGO:001032410.012
cell projection morphogenesisGO:00488582440.012
cellular nitrogen compound biosynthetic processGO:00442712180.012
negative regulation of reproductive processGO:200024230.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
negative regulation of mapk cascadeGO:004340940.012
positive regulation of cell adhesionGO:004578510.012
regulation of purine nucleotide catabolic processGO:003312120.012
organic substance transportGO:0071702580.012
regulation of mrna processingGO:005068430.012
eye morphogenesisGO:00485921440.011
positive regulation of cell cycleGO:004578730.011
somatic muscle developmentGO:000752540.011
cellular amino acid metabolic processGO:000652070.011
regulation of cell activationGO:005086510.011
cranial nerve developmentGO:0021545420.011
organic acid metabolic processGO:0006082310.011
response to organic substanceGO:00100331530.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
macroautophagyGO:001623610.011
regulation of myotube differentiationGO:001083020.011
embryonic appendage morphogenesisGO:0035113300.011
regulation of cytokine productionGO:000181730.011
cell cell signalingGO:0007267520.011
negative regulation of epithelial cell proliferationGO:005068010.011
cellular carbohydrate metabolic processGO:004426240.011
lipid metabolic processGO:0006629520.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
protein localization to plasma membraneGO:007265910.011
peptide metabolic processGO:000651810.011
positive regulation of wound healingGO:009030310.011
stem cell divisionGO:001714510.011
transportGO:00068102200.011
Mouse
leukocyte proliferationGO:007066110.011
long chain fatty acid metabolic processGO:000167610.011
golgi vesicle transportGO:004819330.011
nuclear exportGO:005116810.011
guanosine containing compound metabolic processGO:190106840.011
negative regulation of multi organism processGO:004390130.011
retinoic acid receptor signaling pathwayGO:0048384160.011
regulation of gtpase activityGO:004308720.011
cell fate commitmentGO:0045165990.011
response to hexoseGO:000974630.011
regulation of blood vessel sizeGO:005088020.011
liver developmentGO:0001889960.011
viral processGO:001603210.011
homeostatic processGO:00425921420.011
positive regulation of developmental processGO:0051094500.011
neurological system processGO:0050877620.011
Mouse
inner ear receptor cell differentiationGO:0060113290.011
negative regulation of protein complex assemblyGO:003133310.010
alcohol biosynthetic processGO:004616520.010
autophagyGO:000691440.010
negative regulation of programmed cell deathGO:0043069580.010
hormone secretionGO:004687920.010
negative regulation of metabolic processGO:0009892860.010
convergent extensionGO:00600261180.010
single organism localizationGO:19025782250.010
Mouse
chromosome organization involved in meiosisGO:007019210.010
pectoral fin developmentGO:0033339500.010
negative regulation of protein localization to nucleusGO:190018120.010
medial fin developmentGO:0033338160.010
intracellular mrna localizationGO:000829810.010
pericardium developmentGO:006003910.010
positive regulation of neuron deathGO:190121610.010
cartilage developmentGO:0051216960.010
rna transportGO:005065820.010
negative regulation of signalingGO:0023057960.010
mononuclear cell proliferationGO:003294310.010
protein stabilizationGO:005082120.010
neuromuscular synaptic transmissionGO:000727420.010
purine nucleoside monophosphate catabolic processGO:000912840.010

rpgrb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.093
immune system diseaseDOID:291400.021
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
sensory system diseaseDOID:005015500.018
nervous system diseaseDOID:86300.018
eye and adnexa diseaseDOID:149200.018
eye diseaseDOID:561400.018
disease of metabolismDOID:001466700.018
inherited metabolic disorderDOID:65500.018
musculoskeletal system diseaseDOID:1700.012
muscle tissue diseaseDOID:6600.011
muscular diseaseDOID:008000000.011
myopathyDOID:42300.011
hematopoietic system diseaseDOID:7400.011
organ system cancerDOID:005068600.011
retinal diseaseDOID:567900.011