Danio rerio

13 known processes

pak2b

p21 (CDKN1A)-activated kinase 2b

(Aliases: MGC113857,zgc:113857,fc52b03,wu:fc52b03)

pak2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular metabolic processGO:00313233200.653
Human Yeast
regulation of metabolic processGO:00192223590.553
Human Yeast
regionalizationGO:00030022740.550
cellular component morphogenesisGO:00329893360.533
regulation of cellular biosynthetic processGO:00313262450.458
cellular biosynthetic processGO:00442492860.452
cell morphogenesisGO:00009022890.440
cellular aromatic compound metabolic processGO:00067252950.431
generation of neuronsGO:00486993850.431
negative regulation of cellular processGO:00485232830.418
Human
heterocycle biosynthetic processGO:00181302150.412
regulation of macromolecule metabolic processGO:00602553170.402
Human Yeast
positive regulation of cellular processGO:00485222010.398
Human Yeast
biosynthetic processGO:00090582940.391
larval developmentGO:000216420.391
Worm
cellular macromolecule biosynthetic processGO:00346452240.362
localization of cellGO:00516742440.319
Worm
neuron developmentGO:00486662620.316
heterocycle metabolic processGO:00464832900.311
organic cyclic compound metabolic processGO:19013603010.311
cell projection organizationGO:00300302840.306
response to chemicalGO:00422213200.293
Yeast
central nervous system developmentGO:00074173870.286
regulation of nitrogen compound metabolic processGO:00511712510.282
response to external stimulusGO:00096052640.279
growthGO:00400071740.269
Yeast
developmental growthGO:00485891660.269
negative regulation of biological processGO:00485193040.268
Human Yeast
macromolecule biosynthetic processGO:00090592270.267
cell morphogenesis involved in neuron differentiationGO:00486671630.262
embryo development ending in birth or egg hatchingGO:00097922710.262
Worm
neuron differentiationGO:00301823530.254
regulation of nucleic acid templated transcriptionGO:19035062130.254
organelle organizationGO:00069962270.246
Yeast
embryonic organ developmentGO:00485683810.241
signal transductionGO:00071654550.240
Human Yeast
regulation of gene expressionGO:00104682650.237
Human Yeast
neuron projection developmentGO:00311751800.233
positive regulation of biological processGO:00485182530.232
Human Yeast
regulation of primary metabolic processGO:00800903110.230
Human Yeast
cellular macromolecule metabolic processGO:00442603910.226
Human Yeast Worm
cell cycle processGO:0022402530.218
Yeast
organic cyclic compound biosynthetic processGO:19013622230.213
gene expressionGO:00104672520.211
Human Yeast
neuron projection guidanceGO:0097485860.194
regulation of developmental processGO:00507932470.188
nitrogen compound metabolic processGO:00068073190.188
protein metabolic processGO:00195381830.182
Human Yeast Worm
cell motilityGO:00488702440.178
Worm
cell morphogenesis involved in differentiationGO:00009041950.168
regulation of signal transductionGO:00099662250.166
Human Yeast
regulation of biological qualityGO:00650082630.166
establishment of localizationGO:00512342440.165
Yeast
nucleobase containing compound biosynthetic processGO:00346542050.165
cellular nitrogen compound biosynthetic processGO:00442712180.164
hematopoietic or lymphoid organ developmentGO:00485341910.163
cell part morphogenesisGO:00329902460.163
negative regulation of macromolecule metabolic processGO:0010605760.162
Human Yeast
negative regulation of response to stimulusGO:00485851040.162
negative regulation of signalingGO:0023057960.154
single organism organelle organizationGO:19025891990.150
Yeast
regulation of cell communicationGO:00106462320.145
Human Yeast
regulation of rna metabolic processGO:00512522240.144
organic substance biosynthetic processGO:19015762890.142
digestive tract developmentGO:00485652650.141
dorsal ventral pattern formationGO:00099531250.141
regulation of macromolecule biosynthetic processGO:00105562250.141
cellular component movementGO:00069283350.139
Worm
regulation of nucleobase containing compound metabolic processGO:00192192500.137
nucleic acid metabolic processGO:00903042440.136
locomotionGO:00400113130.132
Worm
tube morphogenesisGO:00352393490.130
rna biosynthetic processGO:00327741810.129
apoptotic processGO:00069151160.129
Human Yeast
cellular nitrogen compound metabolic processGO:00346412900.126
regulation of signalingGO:00230512350.122
Human Yeast
negative regulation of gene expressionGO:0010629650.120
Human Yeast
regulation of rna biosynthetic processGO:20011412130.119
stem cell differentiationGO:00488631170.114
cytoskeleton organizationGO:0007010960.114
Yeast
aromatic compound biosynthetic processGO:00194382170.106
chordate embryonic developmentGO:00430092710.105
cellular protein catabolic processGO:004425740.104
positive regulation of rna biosynthetic processGO:1902680570.102
positive regulation of cellular component biogenesisGO:004408930.102
regulation of cellular macromolecule biosynthetic processGO:20001122220.101
positive regulation of cellular metabolic processGO:0031325940.101
Human Yeast
chromosome organizationGO:0051276310.100
Yeast
regulation of cell shapeGO:000836010.093
meiotic nuclear divisionGO:000712640.092
regulation of cellular component organizationGO:0051128860.092
Yeast
nucleobase containing compound metabolic processGO:00061392740.091
cell projection morphogenesisGO:00488582440.090
regulation of biosynthetic processGO:00098892500.087
hemopoiesisGO:00300971830.086
regulation of transcription from rna polymerase ii promoterGO:00063571140.085
vasculature developmentGO:00019442780.084
blood vessel morphogenesisGO:00485142160.084
negative regulation of developmental processGO:0051093650.084
multicellular organism growthGO:003526440.083
axonogenesisGO:00074091520.082
synaptic growth at neuromuscular junctionGO:005112420.080
agingGO:000756820.078
behaviorGO:0007610740.076
neurological system processGO:0050877620.076
cognitionGO:005089010.076
negative regulation of signal transductionGO:0009968940.075
regulation of cell cycleGO:0051726520.075
Yeast
negative regulation of cell deathGO:0060548600.072
Human
regulation of multicellular organism growthGO:004001440.072
multi organism processGO:00517041340.071
Yeast
positive regulation of macromolecule metabolic processGO:0010604930.070
Human Yeast
rna metabolic processGO:00160702190.070
system processGO:00030081850.067
regulation of synapse assemblyGO:005196330.066
positive regulation of nitrogen compound metabolic processGO:0051173690.064
macromolecule modificationGO:00434121110.063
Human Yeast Worm
regulation of programmed cell deathGO:00430671010.063
Human Yeast
meiotic cell cycle processGO:190304630.062
axis specificationGO:0009798430.062
negative regulation of cell communicationGO:0010648960.062
regulation of apoptotic processGO:0042981980.061
Human Yeast
protein import into nucleusGO:000660630.061
Yeast
maintenance of locationGO:005123540.061
positive regulation of macromolecule biosynthetic processGO:0010557590.060
cell proliferationGO:0008283800.060
immune system processGO:00023762410.060
sexual reproductionGO:0019953360.060
Yeast
regulation of meiotic cell cycleGO:005144510.059
cellular protein metabolic processGO:00442671290.058
Human Yeast Worm
response to stressGO:00069502630.057
Yeast
positive regulation of cellular biosynthetic processGO:0031328680.057
cell migrationGO:00164772370.056
Worm
amine metabolic processGO:000930820.056
regulation of dna replicationGO:000627530.056
protein complex subunit organizationGO:0071822460.055
regulation of protein complex assemblyGO:004325430.055
negative regulation of nucleobase containing compound metabolic processGO:0045934590.055
mitotic dna damage checkpointGO:004477340.054
regulation of transcription dna templatedGO:00063552130.054
neuron projection morphogenesisGO:00488121610.053
axon extensionGO:0048675450.053
positive regulation of cell communicationGO:0010647560.053
Human Yeast
regulation of cell proliferationGO:0042127370.051
angiogenesisGO:00015251580.051
positive regulation of metabolic processGO:00098931080.050
Human Yeast
taxisGO:00423301090.050
enzyme linked receptor protein signaling pathwayGO:00071671060.050
mitotic dna integrity checkpointGO:004477440.050
positive regulation of gene expressionGO:0010628710.049
regulation of mitotic cell cycle phase transitionGO:190199080.049
stem cell maintenanceGO:001982740.049
regulation of mitotic cell cycleGO:0007346250.049
Yeast
deathGO:00162651210.049
Human Yeast
regulation of multicellular organismal processGO:00512392770.049
regulation of synapse organizationGO:005080730.049
brain developmentGO:00074202930.048
programmed cell deathGO:00125011190.048
Human Yeast
cell cycleGO:0007049930.047
Yeast
morphogenesis of an epitheliumGO:00020093330.046
oxoacid metabolic processGO:0043436310.046
regulation of protein catabolic processGO:004217610.046
chemotaxisGO:00069351040.045
mitotic g2 m transition checkpointGO:004481830.045
organelle assemblyGO:00709251100.044
Yeast
transcription from rna polymerase ii promoterGO:0006366800.044
positive regulation of nucleic acid templated transcriptionGO:1903508570.043
protein localization to nucleusGO:003450430.043
Yeast
modification dependent protein catabolic processGO:001994130.043
positive regulation of transportGO:005105020.042
Yeast
regulation of anatomical structure morphogenesisGO:00226031300.042
sensory organ developmentGO:00074233930.042
blood vessel developmentGO:00015682460.042
regulation of protein transportGO:005122330.041
Yeast
anterior posterior pattern specificationGO:00099521520.041
modification dependent macromolecule catabolic processGO:004363230.041
negative regulation of cellular biosynthetic processGO:0031327550.041
regulation of reproductive processGO:200024140.041
cellular component assemblyGO:00226071700.040
Yeast Worm
positive regulation of rna metabolic processGO:0051254590.040
nucleic acid templated transcriptionGO:00976591810.039
mesenchyme developmentGO:00604851270.039
cellular ketone metabolic processGO:0042180110.039
extrinsic apoptotic signaling pathwayGO:009719130.039
Human
cell deathGO:00082191210.039
Human Yeast
negative regulation of nitrogen compound metabolic processGO:0051172590.038
gland developmentGO:00487321430.038
positive regulation of multicellular organismal processGO:0051240520.038
negative regulation of synapse assemblyGO:005196420.038
cellular amine metabolic processGO:004410620.037
regulation of synaptic growth at neuromuscular junctionGO:000858210.037
positive regulation of cellular amine metabolic processGO:003324000.036
small molecule metabolic processGO:0044281770.035
negative regulation of metabolic processGO:0009892860.035
Human Yeast
intracellular signal transductionGO:0035556850.035
Yeast
single organism metabolic processGO:00447102170.033
Yeast
developmental growth involved in morphogenesisGO:0060560860.033
developmental cell growthGO:0048588520.033
regulation of cellular protein catabolic processGO:190336210.033
regulation of cell deathGO:00109411030.033
Human Yeast
regulation of neuron projection developmentGO:0010975400.033
cell surface receptor signaling pathwayGO:00071663250.033
Human Yeast
convergent extensionGO:00600261180.032
actin filament based processGO:0030029640.032
regulation of cell sizeGO:0008361290.032
digestive tract morphogenesisGO:00485462310.031
wnt signaling pathwayGO:0016055800.031
regulation of developmental growthGO:0048638380.031
mitotic sister chromatid segregationGO:000007060.031
negative regulation of nervous system developmentGO:0051961220.031
regulation of response to stimulusGO:00485832690.031
Human Yeast
single organism localizationGO:19025782250.030
Yeast
development of primary female sexual characteristicsGO:004654540.030
axon developmentGO:00615641660.029
segmentationGO:0035282970.029
positive regulation of transcription dna templatedGO:0045893570.029
astral microtubule organizationGO:003095310.029
negative regulation of biosynthetic processGO:0009890550.029
immune system developmentGO:00025201910.029
negative regulation of programmed cell deathGO:0043069580.028
Human
locomotor rhythmGO:004547530.028
digestive system developmentGO:00551232890.028
heart morphogenesisGO:00030071560.028
response to nutrientGO:000758430.028
meiotic chromosome segregationGO:004513230.028
regenerationGO:0031099910.028
regulation of cellular component sizeGO:0032535300.028
neuroblast proliferationGO:000740520.028
regulation of nervous system developmentGO:0051960900.027
forebrain developmentGO:0030900960.027
cell agingGO:000756920.027
regulation of cell differentiationGO:00455951420.027
proteolysis involved in cellular protein catabolic processGO:005160330.027
positive regulation of programmed cell deathGO:0043068290.027
Human Yeast
cellular component biogenesisGO:00440851780.027
Yeast Worm
regulation of multicellular organismal developmentGO:20000262230.026
multicellular organismal homeostasisGO:0048871290.026
response to drugGO:004249330.026
epithelial tube morphogenesisGO:00605621480.026
positive regulation of catabolic processGO:000989640.026
regulation of organelle organizationGO:0033043290.026
Yeast
carboxylic acid metabolic processGO:0019752220.026
positive regulation of cell cycleGO:004578730.025
regulation of cell activationGO:005086510.025
locomotory behaviorGO:0007626340.025
regulation of canonical wnt signaling pathwayGO:0060828340.025
regulation of catalytic activityGO:0050790550.024
Human Yeast
wound healingGO:0042060900.024
adult behaviorGO:003053420.024
regulation of protein localization to nucleusGO:190018020.024
Yeast
regulation of extrinsic apoptotic signaling pathwayGO:200123630.024
Human
eye developmentGO:00016542770.024
heart developmentGO:00075073130.024
embryonic organ morphogenesisGO:00485622740.023
homeostasis of number of cellsGO:0048872620.023
mesoderm developmentGO:0007498880.023
positive regulation of cell activationGO:005086710.023
forebrain cell migrationGO:002188510.023
regulation of intracellular signal transductionGO:1902531570.023
Yeast
skeletal system developmentGO:00015011810.023
regulation of peptidyl tyrosine phosphorylationGO:005073010.023
Human
regulation of growthGO:0040008420.023
regulation of cellular ketone metabolic processGO:001056570.022
negative regulation of dna replicationGO:000815620.022
negative regulation of catabolic processGO:000989530.022
regulation of circadian rhythmGO:004275240.022
mitotic g2 dna damage checkpointGO:000709530.022
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.022
myeloid cell differentiationGO:0030099860.022
lipid storageGO:001991510.022
negative regulation of cell cycle processGO:001094890.022
embryonic hemopoiesisGO:0035162530.022
mitotic cell cycle checkpointGO:000709350.022
negative regulation of cellular component organizationGO:0051129160.021
neuron projection extensionGO:1990138450.021
response to woundingGO:00096111160.021
determination of left right symmetryGO:00073681790.021
negative regulation of cell projection organizationGO:003134590.021
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.021
cellular amino acid metabolic processGO:000652070.021
determination of bilateral symmetryGO:00098552040.021
response to abiotic stimulusGO:00096281220.021
Yeast
protein secretionGO:000930610.020
positive regulation of response to stimulusGO:0048584800.020
Human Yeast
phagocytosisGO:000690930.020
macromolecule localizationGO:0033036540.020
Yeast
positive regulation of biosynthetic processGO:0009891680.020
meiosis iGO:000712710.020
negative regulation of multicellular organismal processGO:0051241690.020
regulation of response to stressGO:0080134360.020
reproductive processGO:0022414400.020
Yeast Worm
centrosome cycleGO:000709810.019
positive regulation of developmental processGO:0051094500.019
single organism nuclear importGO:190259330.019
Yeast
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.019
regulation of cellular protein metabolic processGO:0032268520.019
Human Yeast
regulation of gene expression epigeneticGO:0040029110.019
erythrocyte differentiationGO:0030218540.019
positive regulation of signalingGO:0023056560.019
Human Yeast
internal protein amino acid acetylationGO:000647520.019
positive regulation of neural precursor cell proliferationGO:200017910.019
nerve developmentGO:0021675450.019
positive regulation of cellular catabolic processGO:003133130.018
viral processGO:001603210.018
biological adhesionGO:0022610400.018
protein localizationGO:0008104400.018
Yeast
phosphate containing compound metabolic processGO:00067961080.018
Human Yeast Worm
compound eye developmentGO:004874920.018
transcription dna templatedGO:00063511810.018
multicellular organism reproductionGO:0032504350.018
regulation of apoptotic signaling pathwayGO:2001233120.018
Human
blood circulationGO:0008015870.018
regulation of cell projection organizationGO:0031344440.018
negative regulation of rna biosynthetic processGO:1902679450.018
developmental maturationGO:0021700340.018
regulation of localizationGO:00328791040.017
Yeast
cranial nerve developmentGO:0021545420.017
internal peptidyl lysine acetylationGO:001839320.017
positive regulation of cell deathGO:0010942290.017
Human Yeast
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.017
negative regulation of neuron projection regenerationGO:007057140.017
multicellular organismal reproductive processGO:0048609350.017
cellular response to stressGO:0033554620.017
Yeast
developmental process involved in reproductionGO:0003006270.016
Worm
ubiquitin dependent protein catabolic processGO:000651130.016
canonical wnt signaling pathwayGO:0060070480.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.016
regulation of intracellular protein transportGO:003315730.016
Yeast
positive regulation of signal transductionGO:0009967560.016
Human Yeast
cell death in response to oxidative stressGO:003647320.016
negative regulation of ras protein signal transductionGO:004658010.016
transportGO:00068102200.016
Yeast
regulation of anatomical structure sizeGO:0090066330.016
somite developmentGO:0061053960.016
circulatory system processGO:0003013870.016
microtubule organizing center organizationGO:003102310.016
somitogenesisGO:0001756870.015
synaptic target recognitionGO:000803910.015
sister chromatid segregationGO:000081960.015
organic acid metabolic processGO:0006082310.015
neuron recognitionGO:0008038180.015
negative regulation of transcription dna templatedGO:0045892450.015
negative regulation of rna metabolic processGO:0051253480.015
meiosis iiGO:000713510.015
cardiac cell fate commitmentGO:006091110.015
establishment of organelle localizationGO:0051656450.015
regulation of sodium ion transportGO:000202820.015
negative regulation of mitotic cell cycle phase transitionGO:190199150.014
neuron neuron synaptic transmissionGO:000727010.014
heart processGO:0003015710.014
transmembrane transportGO:00550851200.014
Yeast
head developmentGO:00603223030.014
axon guidanceGO:0007411860.014
actin cytoskeleton organizationGO:0030036630.014
negative regulation of apoptotic processGO:0043066550.014
Human
double strand break repair via homologous recombinationGO:000072410.014
regulation of neural precursor cell proliferationGO:200017730.014
regulation of cell developmentGO:00602841000.014
endocytosisGO:0006897160.014
response to organic substanceGO:00100331530.014
Yeast
cytokinesisGO:000091030.014
Yeast
nuclear divisionGO:0000280230.014
Yeast
regulation of cellular response to oxidative stressGO:190040720.014
positive regulation of apoptotic signaling pathwayGO:200123510.013
Human
positive regulation of reproductive processGO:200024320.013
regulation of cell morphogenesisGO:0022604420.013
female gonad developmentGO:000858540.013
dendrite guidanceGO:007098300.013
regulation of protein metabolic processGO:0051246560.013
Human Yeast
peptidyl lysine acetylationGO:001839420.013
regulation of wnt signaling pathwayGO:0030111530.013
regulation of glial cell differentiationGO:004568540.013
cell projection assemblyGO:0030031640.013
cellular response to extracellular stimulusGO:003166820.013
centrosome organizationGO:005129710.013
negative regulation of macromolecule biosynthetic processGO:0010558480.013
negative regulation of cell differentiationGO:0045596460.013
regulation of cellular component movementGO:0051270550.013
post embryonic organ developmentGO:004856940.013
maternal determination of anterior posterior axis embryoGO:000835840.013
specification of symmetryGO:00097992040.013
oocyte anterior posterior axis specificationGO:000731440.013
regulation of establishment of protein localizationGO:007020140.012
Yeast
cellular response to external stimulusGO:007149620.012
nuclear transportGO:005116940.012
Yeast
stem cell developmentGO:0048864820.012
retinal ganglion cell axon guidanceGO:0031290350.012
regulation of chromosome segregationGO:005198310.012
regulation of protein import into nucleusGO:004230620.012
Yeast
proteasomal protein catabolic processGO:001049820.012
negative regulation of secretion by cellGO:190353120.012
intracellular receptor signaling pathwayGO:0030522300.012
positive regulation of chromosome organizationGO:200125210.012
embryonic heart tube morphogenesisGO:00031431080.012
negative regulation of multi organism processGO:004390130.012
recombinational repairGO:000072510.012
regulation of cellular amino acid metabolic processGO:000652100.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
Human
response to hydrogen peroxideGO:004254230.012
negative regulation of myeloid cell differentiationGO:004563810.012
histone deacetylationGO:001657520.012
meiotic spindle organizationGO:000021210.012
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.012
b cell activationGO:004211320.011
exocrine system developmentGO:0035272280.011
cell fate commitmentGO:0045165990.011
positive regulation of protein complex assemblyGO:003133420.011
chromatin modificationGO:0016568210.011
Yeast
phosphorylationGO:0016310690.011
Human Yeast Worm
gamete generationGO:0007276330.011
macromolecular complex assemblyGO:0065003350.011
Yeast
cell substrate adhesionGO:003158940.011
myeloid cell homeostasisGO:0002262560.011
organism emergence from protective structureGO:007168440.011
response to uvGO:000941130.011
regulation of cell cycle processGO:0010564200.011
Yeast
cell matrix adhesionGO:000716040.011
mitotic cell cycle processGO:1903047480.011
Yeast
microtubule based processGO:0007017600.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
neurotransmitter secretionGO:000726920.011
negative regulation of cellular metabolic processGO:0031324770.011
Human
regulation of mrna processingGO:005068430.011
cell adhesionGO:0007155400.011
positive regulation of stem cell proliferationGO:200064810.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
exocytosisGO:000688710.011
homeostatic processGO:00425921420.011
protein polymerizationGO:005125840.011
regulation of cytoplasmic transportGO:190364940.010
Yeast
epithelial cell differentiationGO:00308551160.010
positive regulation of chromatin modificationGO:190331010.010
neuromuscular process controlling balanceGO:005088530.010
protein phosphorylationGO:0006468470.010
Human Yeast Worm
macromolecule deacylationGO:009873230.010
energy reserve metabolic processGO:000611220.010
cell recognitionGO:0008037190.010
gastrulationGO:00073692080.010
liver developmentGO:0001889960.010
regulation of protein maturationGO:1903317100.010
Human

pak2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.013
disease of anatomical entityDOID:700.012