Danio rerio

0 known processes

pdk3a

pyruvate dehydrogenase kinase, isozyme 3a

(Aliases: pdk3)

pdk3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.091
agingGO:000756820.063
cognitionGO:005089010.047
single organism localizationGO:19025782250.047
maintenance of locationGO:005123540.045
positive regulation of cellular catabolic processGO:003133130.044
signal transductionGO:00071654550.042
positive regulation of transportGO:005105020.042
neurotransmitter transportGO:000683620.039
cellular response to external stimulusGO:007149620.038
multicellular organism growthGO:003526440.037
response to chemicalGO:00422213200.037
positive regulation of catabolic processGO:000989640.037
single organism transportGO:00447652060.036
synaptic growth at neuromuscular junctionGO:005112420.036
regulation of cytokine productionGO:000181730.035
cell surface receptor signaling pathwayGO:00071663250.034
negative regulation of protein phosphorylationGO:000193340.033
lipid storageGO:001991510.033
transportGO:00068102200.033
establishment of protein localization to organelleGO:007259440.033
establishment of localizationGO:00512342440.032
phagocytosisGO:000690930.032
regulation of protein complex assemblyGO:004325430.032
cellular response to extracellular stimulusGO:003166820.032
regulation of establishment of protein localizationGO:007020140.032
nitrogen compound metabolic processGO:00068073190.031
regulation of synaptic plasticityGO:004816710.031
adult behaviorGO:003053420.031
regulation of synapse organizationGO:005080730.030
response to carbohydrateGO:000974330.030
head developmentGO:00603223030.030
organonitrogen compound metabolic processGO:1901564740.029
gtp metabolic processGO:004603940.029
autophagyGO:000691440.029
gtp catabolic processGO:000618420.029
nucleocytoplasmic transportGO:000691340.029
lipid catabolic processGO:001604240.028
amine metabolic processGO:000930820.028
cellular response to nutrient levelsGO:003166920.028
regulation of multicellular organism growthGO:004001440.028
regulation of synaptic growth at neuromuscular junctionGO:000858210.028
cellular nitrogen compound metabolic processGO:00346412900.027
stem cell proliferationGO:007208940.027
cellular response to starvationGO:000926710.027
single organism metabolic processGO:00447102170.027
regulation of synapse assemblyGO:005196330.027
i kappab kinase nf kappab signalingGO:000724940.027
regulation of tube sizeGO:003515020.027
nuclear transportGO:005116940.026
guanosine containing compound metabolic processGO:190106840.026
protein localization to nucleusGO:003450430.026
small molecule metabolic processGO:0044281770.026
neurotransmitter secretionGO:000726920.026
regulation of circadian rhythmGO:004275240.026
regulation of signalingGO:00230512350.026
cellular biosynthetic processGO:00442492860.026
response to external stimulusGO:00096052640.026
positive regulation of cell cycleGO:004578730.026
regulation of protein transportGO:005122330.026
neuron differentiationGO:00301823530.026
proteolysis involved in cellular protein catabolic processGO:005160330.025
organic cyclic compound metabolic processGO:19013603010.025
regulation of metal ion transportGO:001095940.025
gene expressionGO:00104672520.025
response to drugGO:004249330.025
sensory perception of chemical stimulusGO:000760630.025
compound eye developmentGO:004874920.025
regulation of signal transductionGO:00099662250.025
cellular macromolecule metabolic processGO:00442603910.025
cell morphogenesisGO:00009022890.025
regulation of cell communicationGO:00106462320.024
brain developmentGO:00074202930.024
single organism nuclear importGO:190259330.024
biosynthetic processGO:00090582940.024
nuclear importGO:005117030.024
positive regulation of cellular component biogenesisGO:004408930.024
rna localizationGO:000640340.024
cellular protein catabolic processGO:004425740.024
neuron neuron synaptic transmissionGO:000727010.024
regulation of biological qualityGO:00650082630.024
organelle fusionGO:004828430.024
g protein coupled receptor signaling pathwayGO:0007186740.023
amino acid transportGO:000686520.023
organic substance biosynthetic processGO:19015762890.023
modification dependent macromolecule catabolic processGO:004363230.023
cell part morphogenesisGO:00329902460.023
cellular component morphogenesisGO:00329893360.023
establishment of synaptic vesicle localizationGO:009748010.023
mitochondrion organizationGO:000700540.023
synaptic vesicle transportGO:004848910.023
negative regulation of catabolic processGO:000989530.023
protein targeting to nucleusGO:004474430.023
synaptic vesicle localizationGO:009747910.023
generation of neuronsGO:00486993850.023
locomotionGO:00400113130.023
sensory organ developmentGO:00074233930.023
modification dependent protein catabolic processGO:001994130.022
system processGO:00030081850.022
morphogenesis of an epitheliumGO:00020093330.022
regulation of cytoplasmic transportGO:190364940.022
guanosine containing compound catabolic processGO:190106920.022
protein import into nucleusGO:000660630.022
cellular amine metabolic processGO:004410620.022
response to hexoseGO:000974630.022
central nervous system developmentGO:00074173870.022
protein importGO:001703830.022
tube morphogenesisGO:00352393490.022
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.022
nucleobase containing compound metabolic processGO:00061392740.022
heterocycle metabolic processGO:00464832900.021
regulation of multicellular organismal processGO:00512392770.021
ubiquitin dependent protein catabolic processGO:000651130.021
hormone secretionGO:004687920.021
regulation of bindingGO:005109830.021
regulation of protein catabolic processGO:004217610.021
regulation of cellular amine metabolic processGO:003323800.021
cellular component disassemblyGO:002241110.021
meiotic nuclear divisionGO:000712640.021
exocytosisGO:000688710.021
negative regulation of kinase activityGO:003367340.021
macroautophagyGO:001623610.021
regulation of i kappab kinase nf kappab signalingGO:004312240.020
cell projection organizationGO:00300302840.020
membrane fusionGO:006102520.020
regulation of response to stimulusGO:00485832690.020
hormone transportGO:000991420.020
response to monosaccharideGO:003428430.020
chemosensory behaviorGO:000763510.020
cellular component movementGO:00069283350.020
macromolecular complex disassemblyGO:003298410.020
regionalizationGO:00030022740.020
positive regulation of purine nucleotide catabolic processGO:003312310.020
regulation of nitrogen compound metabolic processGO:00511712510.020
regulation of neurotransmitter secretionGO:004692810.020
eye developmentGO:00016542770.020
regulation of gtp catabolic processGO:003312420.020
regulation of nucleotide catabolic processGO:003081120.020
regulation of blood vessel sizeGO:005088020.020
regulation of nucleoside metabolic processGO:000911820.020
cell projection morphogenesisGO:00488582440.019
neuroblast proliferationGO:000740520.019
protein complex disassemblyGO:004324110.019
regulation of reproductive processGO:200024140.019
positive regulation of gtp catabolic processGO:003312610.019
smooth muscle contractionGO:000693920.019
regulation of nucleocytoplasmic transportGO:004682220.019
regulation of intracellular protein transportGO:003315730.019
stem cell maintenanceGO:001982740.019
regulation of autophagyGO:001050630.019
regulation of muscle contractionGO:000693730.019
regulation of cellular metabolic processGO:00313233200.019
positive regulation of secretionGO:005104710.019
sleepGO:003043110.019
organic cyclic compound biosynthetic processGO:19013622230.019
carboxylic acid metabolic processGO:0019752220.019
vasculature developmentGO:00019442780.019
response to glucoseGO:000974930.019
regulation of blood pressureGO:000821710.019
cellular amide metabolic processGO:004360340.018
organic acid metabolic processGO:0006082310.018
embryonic organ developmentGO:00485683810.018
regulation of metabolic processGO:00192223590.018
actin polymerization or depolymerizationGO:000815420.018
cellular aromatic compound metabolic processGO:00067252950.018
immune system processGO:00023762410.018
regulation of cell activationGO:005086510.018
positive regulation of gtpase activityGO:004354710.018
cellular carbohydrate metabolic processGO:004426240.018
meiotic cell cycle processGO:190304630.018
cellular response to chemical stimulusGO:00708871570.018
dicarboxylic acid transportGO:000683510.018
response to stressGO:00069502630.018
protein polymerizationGO:005125840.018
regulation of cellular amino acid metabolic processGO:000652100.018
neuron developmentGO:00486662620.018
cellular component biogenesisGO:00440851780.018
establishment of protein localization to plasma membraneGO:009000210.018
negative regulation of biological processGO:00485193040.018
rna metabolic processGO:00160702190.018
regulation of macromolecule metabolic processGO:00602553170.018
determination of bilateral symmetryGO:00098552040.018
lateral inhibitionGO:004633110.018
negative regulation of protein complex assemblyGO:003133310.017
positive regulation of nucleoside metabolic processGO:004597910.017
endosomal transportGO:001619720.017
regulation of response to nutrient levelsGO:003210710.017
oxoacid metabolic processGO:0043436310.017
protein metabolic processGO:00195381830.017
golgi vesicle transportGO:004819330.017
regulation of neural precursor cell proliferationGO:200017730.017
secondary metabolic processGO:001974830.017
regulation of cell shapeGO:000836010.017
positive regulation of cytokine productionGO:000181920.017
regulation of multicellular organismal developmentGO:20000262230.017
regulation of purine nucleotide catabolic processGO:003312120.017
regulation of response to extracellular stimulusGO:003210410.017
protein secretionGO:000930610.017
peptide transportGO:001583310.017
regulation of transmembrane transporter activityGO:002289820.017
regulation of primary metabolic processGO:00800903110.017
transmembrane transportGO:00550851200.017
regulation of developmental processGO:00507932470.017
atp catabolic processGO:000620040.017
hematopoietic or lymphoid organ developmentGO:00485341910.017
sequestering of calcium ionGO:005120830.017
homeostatic processGO:00425921420.017
ribonucleoside monophosphate catabolic processGO:000915840.017
negative regulation of cellular processGO:00485232830.017
positive regulation of nucleotide catabolic processGO:003081310.017
regulation of nucleobase containing compound metabolic processGO:00192192500.017
immune system developmentGO:00025201910.017
nucleoside monophosphate catabolic processGO:000912540.017
specification of symmetryGO:00097992040.017
negative regulation of protein kinase activityGO:000646940.017
ion transportGO:00068111140.016
proteasomal protein catabolic processGO:001049820.016
response to organic substanceGO:00100331530.016
single organism membrane fusionGO:004480120.016
cellular ketone metabolic processGO:0042180110.016
positive regulation of blood circulationGO:190352420.016
cellular response to biotic stimulusGO:007121630.016
cellular amino acid metabolic processGO:000652070.016
cellular response to lipopolysaccharideGO:007122230.016
positive regulation of cytoskeleton organizationGO:005149530.016
dorsal ventral pattern formationGO:00099531250.016
regulation of dendrite developmentGO:005077330.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
digestive tract morphogenesisGO:00485462310.016
nucleobase containing compound biosynthetic processGO:00346542050.016
neuromuscular synaptic transmissionGO:000727420.016
positive regulation of biological processGO:00485182530.016
positive regulation of secretion by cellGO:190353210.016
regulation of cellular ketone metabolic processGO:001056570.016
protein localization to plasma membraneGO:007265910.016
cell morphogenesis involved in differentiationGO:00009041950.016
regulation of inflammatory responseGO:005072720.016
response to uvGO:000941130.016
heterocycle biosynthetic processGO:00181302150.016
membrane invaginationGO:001032410.016
regulation of transporter activityGO:003240920.015
regulation of neurotransmitter transportGO:005158810.015
cell substrate adhesionGO:003158940.015
axonogenesisGO:00074091520.015
cytokinesisGO:000091030.015
regulation of ion transmembrane transporter activityGO:003241220.015
neuron projection developmentGO:00311751800.015
mechanosensory behaviorGO:000763820.015
circadian sleep wake cycle sleepGO:005080210.015
regulation of protein ubiquitinationGO:003139630.015
cortical cytoskeleton organizationGO:003086510.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
sensory perception of painGO:001923310.015
regulation of gene expressionGO:00104682650.015
regulation of epithelial cell proliferationGO:005067830.015
actin filament based movementGO:003004810.015
alcohol biosynthetic processGO:004616520.015
negative regulation of cellular catabolic processGO:003133030.015
digestive tract developmentGO:00485652650.015
response to hydrogen peroxideGO:004254230.015
regulation of phGO:000688530.015
regulation of gtpase activityGO:004308720.015
organism emergence from protective structureGO:007168440.015
response to topologically incorrect proteinGO:003596620.015
phototransductionGO:000760220.015
purine nucleoside monophosphate catabolic processGO:000912840.015
response to abiotic stimulusGO:00096281220.015
digestive system developmentGO:00551232890.015
circadian sleep wake cycleGO:004274520.015
phagocytosis engulfmentGO:000691110.015
sequestering of metal ionGO:005123830.015
cellular response to molecule of bacterial originGO:007121930.015
hemopoiesisGO:00300971830.015
protein acetylationGO:000647320.015
cellular component assemblyGO:00226071700.014
adherens junction organizationGO:003433240.014
carbohydrate biosynthetic processGO:001605110.014
positive regulation of cellular processGO:00485222010.014
regulation of protein import into nucleusGO:004230620.014
spermatid developmentGO:000728620.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
regulation of cellular biosynthetic processGO:00313262450.014
negative regulation of synapse assemblyGO:005196420.014
somatic muscle developmentGO:000752540.014
actin filament polymerizationGO:003004120.014
pigment granule localizationGO:0051875250.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
axon developmentGO:00615641660.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
blood circulationGO:0008015870.014
regulation of sodium ion transportGO:000202820.014
cellular macromolecule biosynthetic processGO:00346452240.014
neuron projection morphogenesisGO:00488121610.014
heart developmentGO:00075073130.014
glucose homeostasisGO:004259310.014
macromolecule biosynthetic processGO:00090592270.014
response to alkaloidGO:004327920.014
positive regulation of protein complex assemblyGO:003133420.014
regulation of wound healingGO:006104120.014
regulation of calcium ion transportGO:005192420.014
chordate embryonic developmentGO:00430092710.014
multicellular organismal signalingGO:0035637220.014
regulation of stem cell proliferationGO:007209120.014
cilium morphogenesisGO:0060271850.014
nucleic acid metabolic processGO:00903042440.014
regulation of protein localization to nucleusGO:190018020.014
retina development in camera type eyeGO:00600411460.014
regulation of reactive oxygen species metabolic processGO:200037720.014
xenobiotic metabolic processGO:000680540.014
blood vessel developmentGO:00015682460.014
development of primary female sexual characteristicsGO:004654540.014
post embryonic organ developmentGO:004856940.014
female gonad developmentGO:000858540.013
negative regulation of defense responseGO:003134820.013
anterior posterior pattern specificationGO:00099521520.013
internal protein amino acid acetylationGO:000647520.013
regulation of systemic arterial blood pressureGO:000307310.013
embryo development ending in birth or egg hatchingGO:00097922710.013
developmental growthGO:00485891660.013
phosphorus metabolic processGO:00067931090.013
transcription dna templatedGO:00063511810.013
regulation of cellular protein catabolic processGO:190336210.013
organelle organizationGO:00069962270.013
aromatic compound biosynthetic processGO:00194382170.013
cell matrix adhesionGO:000716040.013
ion transmembrane transportGO:0034220910.013
monovalent inorganic cation transportGO:0015672420.013
cytoplasm organizationGO:000702840.013
regulation of protein complex disassemblyGO:004324410.013
cellular response to radiationGO:007147840.013
regulation of macromolecule biosynthetic processGO:00105562250.013
embryonic organ morphogenesisGO:00485622740.013
female sex differentiationGO:004666040.013
phosphate containing compound metabolic processGO:00067961080.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
nucleic acid templated transcriptionGO:00976591810.013
cellular response to organic substanceGO:00713101050.013
regulation of sequestering of calcium ionGO:005128240.013
cellular pigmentationGO:0033059300.013
negative regulation of intracellular transportGO:003238730.013
sensory organ morphogenesisGO:00905962000.013
neurological system processGO:0050877620.013
positive regulation of inflammatory responseGO:005072910.013
regulation of hormone secretionGO:004688320.013
peptidyl serine modificationGO:001820920.013
peptide metabolic processGO:000651810.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
membrane hyperpolarizationGO:006008110.013
striated muscle cell developmentGO:00550021080.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
response to unfolded proteinGO:000698620.013
melanin metabolic processGO:000658220.013
peptidyl lysine acetylationGO:001839420.013
symbiosis encompassing mutualism through parasitismGO:004440340.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
negative regulation of mapk cascadeGO:004340940.012
response to amino acidGO:004320020.012
cellular lipid catabolic processGO:004424230.012
carbohydrate derivative metabolic processGO:1901135610.012
regulation of neuronal synaptic plasticityGO:004816810.012
negative regulation of sequestering of calcium ionGO:005128340.012
vacuolar transportGO:000703420.012
hatchingGO:003518840.012
positive regulation of dna metabolic processGO:005105410.012
regulation of protein targetingGO:190353320.012
regulation of mrna processingGO:005068430.012
negative regulation of cytoplasmic transportGO:190365020.012
negative regulation of secretionGO:005104820.012
protein acylationGO:004354330.012
germ line stem cell maintenanceGO:003071820.012
growthGO:00400071740.012
small molecule catabolic processGO:004428230.012
rna transportGO:005065820.012
muscle cell developmentGO:00550011150.012
fatty acid transportGO:001590810.012
tissue remodelingGO:004877140.012
regulation of biosynthetic processGO:00098892500.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
regulation of carbohydrate metabolic processGO:000610940.012
water transportGO:0006833150.012
single organism organelle organizationGO:19025891990.012
carbohydrate homeostasisGO:003350010.012
actin mediated cell contractionGO:007025210.012
muscle structure developmentGO:00610611960.012
positive regulation of immune effector processGO:000269930.012
positive regulation of camp biosynthetic processGO:003081920.012
interspecies interaction between organismsGO:004441940.012
determination of left right symmetryGO:00073681790.012
regulation of endocrine processGO:004406020.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
er nucleus signaling pathwayGO:000698420.012
endocrine processGO:005088620.012
cellular component assembly involved in morphogenesisGO:00109271070.012
spermatid differentiationGO:004851520.012
energy reserve metabolic processGO:000611220.012
cell migrationGO:00164772370.012
positive regulation of cell activationGO:005086710.012
developmental programmed cell deathGO:001062340.012
single organism biosynthetic processGO:0044711710.012
b cell activationGO:004211320.012
positive regulation of cellular amine metabolic processGO:003324000.012
multicellular organismal response to stressGO:003355520.012
rna biosynthetic processGO:00327741810.012
extrinsic apoptotic signaling pathwayGO:009719130.012
gastrulationGO:00073692080.012
inorganic cation transmembrane transportGO:0098662500.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
camera type eye developmentGO:00430102220.012
cellular localizationGO:0051641970.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
endoplasmic reticulum unfolded protein responseGO:003096820.012
protein homooligomerizationGO:005126030.012
regulation of protein polymerizationGO:003227120.012
peptidyl serine phosphorylationGO:001810510.011
centrosome organizationGO:005129710.011
positive regulation of camp metabolic processGO:003081620.011
cellular response to topologically incorrect proteinGO:003596720.011
negative regulation of protein transportGO:005122430.011
positive regulation of cell divisionGO:005178120.011
nucleic acid transportGO:005065720.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
monoamine transportGO:001584410.011
action potentialGO:0001508190.011
response to xenobiotic stimulusGO:0009410450.011
catechol containing compound metabolic processGO:000971220.011
gas transportGO:001566930.011
protein dephosphorylationGO:000647030.011
regulation of protein depolymerizationGO:190187910.011
negative regulation of intracellular protein transportGO:009031730.011
cellular protein complex disassemblyGO:004362410.011
oocyte anterior posterior axis specificationGO:000731440.011
production of molecular mediator of immune responseGO:000244020.011
response to nutrientGO:000758430.011
regulation of protein bindingGO:004339330.011
peptidyl threonine phosphorylationGO:001810710.011
negative regulation of map kinase activityGO:004340720.011
leukocyte proliferationGO:007066110.011
circulatory system processGO:0003013870.011
regulation of apoptotic processGO:0042981980.011
protein depolymerizationGO:005126110.011
regulation of neurological system processGO:003164420.011
apoptotic processGO:00069151160.011
localization of cellGO:00516742440.011
stem cell divisionGO:001714510.011
fertilizationGO:000956630.011
regulation of organ growthGO:004662030.011
cytosolic calcium ion transportGO:006040130.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
pigmentationGO:0043473850.011
zymogen activationGO:003163830.011
deathGO:00162651210.011
cell deathGO:00082191210.011
regulation of circadian sleep wake cycle sleepGO:004518710.011
startle responseGO:000196440.011
regulation of programmed cell deathGO:00430671010.011
cell motilityGO:00488702440.011
regulation of oocyte developmentGO:006028130.011
cellular protein metabolic processGO:00442671290.011
regulation of transcription dna templatedGO:00063552130.011
fluid transportGO:0042044170.011
inner ear developmentGO:00488391260.011
multi organism processGO:00517041340.011
heart contractionGO:0060047710.011
positive regulation of heart contractionGO:004582320.011
epithelial cell differentiationGO:00308551160.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
organelle assemblyGO:00709251100.011
cellular response to reactive oxygen speciesGO:003461420.011
regulation of anatomical structure morphogenesisGO:00226031300.010
regulation of meiotic cell cycleGO:005144510.010
response to endogenous stimulusGO:0009719830.010
cellular response to light stimulusGO:007148240.010
establishment of rna localizationGO:005123630.010
response to external biotic stimulusGO:0043207970.010
intracellular signal transductionGO:0035556850.010
carbon dioxide transportGO:001567030.010
transcription from rna polymerase ii promoterGO:0006366800.010
meiotic chromosome segregationGO:004513230.010
angiogenesisGO:00015251580.010
pigment granule transportGO:0051904190.010
muscle cell differentiationGO:00426921390.010
wound healingGO:0042060900.010
intracellular mrna localizationGO:000829810.010
positive regulation of myeloid cell differentiationGO:004563920.010
endocrine hormone secretionGO:006098620.010
carboxylic acid catabolic processGO:004639530.010
regulation of multicellular organismal metabolic processGO:004424620.010

pdk3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.019
musculoskeletal system diseaseDOID:1700.015
disease of cellular proliferationDOID:1456600.014
disease of metabolismDOID:001466700.014
cancerDOID:16200.012
organ system cancerDOID:005068600.012
cardiovascular system diseaseDOID:128700.012
inherited metabolic disorderDOID:65500.010