Danio rerio

0 known processes

pmelb

premelanosome protein b

(Aliases: silvb,silverb)

pmelb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
retina development in camera type eyeGO:00600411460.246
neuron differentiationGO:00301823530.176
generation of neuronsGO:00486993850.171
eye developmentGO:00016542770.128
response to chemicalGO:00422213200.116
camera type eye developmentGO:00430102220.112
cell projection morphogenesisGO:00488582440.105
cell part morphogenesisGO:00329902460.100
sensory organ developmentGO:00074233930.097
skeletal system developmentGO:00015011810.091
regulation of macromolecule metabolic processGO:00602553170.091
regulation of nitrogen compound metabolic processGO:00511712510.090
negative regulation of protein kinase activityGO:000646940.085
vitamin a metabolic processGO:000677610.085
neuron developmentGO:00486662620.082
response to organic substanceGO:00100331530.078
response to stressGO:00069502630.075
regulation of metabolic processGO:00192223590.072
cellular component morphogenesisGO:00329893360.068
chordate embryonic developmentGO:00430092710.067
embryonic organ morphogenesisGO:00485622740.064
locomotionGO:00400113130.062
signal transductionGO:00071654550.060
heart morphogenesisGO:00030071560.058
regulation of gene expressionGO:00104682650.058
gene expressionGO:00104672520.057
regulation of nucleobase containing compound metabolic processGO:00192192500.056
cell projection organizationGO:00300302840.056
aromatic compound biosynthetic processGO:00194382170.056
Mouse
nucleic acid metabolic processGO:00903042440.055
system processGO:00030081850.053
axonogenesisGO:00074091520.052
photoreceptor cell fate commitmentGO:004655210.052
cellular macromolecule metabolic processGO:00442603910.051
transportGO:00068102200.050
lipid storageGO:001991510.049
vasculature developmentGO:00019442780.048
biosynthetic processGO:00090582940.048
Mouse
embryonic organ developmentGO:00485683810.048
cellular component movementGO:00069283350.047
compound eye developmentGO:004874920.047
cellular nitrogen compound metabolic processGO:00346412900.046
mesenchymal cell differentiationGO:0048762870.045
nitrogen compound metabolic processGO:00068073190.043
brain developmentGO:00074202930.042
phagocytosisGO:000690930.042
response to external stimulusGO:00096052640.042
regulation of neural precursor cell proliferationGO:200017730.042
head developmentGO:00603223030.041
cellular response to chemical stimulusGO:00708871570.040
regulation of biological qualityGO:00650082630.040
negative regulation of protein phosphorylationGO:000193340.040
deathGO:00162651210.039
stem cell proliferationGO:007208940.038
mesenchyme developmentGO:00604851270.038
neuron projection morphogenesisGO:00488121610.037
cellular biosynthetic processGO:00442492860.037
Mouse
regulation of transcription dna templatedGO:00063552130.037
neuron projection developmentGO:00311751800.037
response to drugGO:004249330.036
regulation of cell communicationGO:00106462320.036
organelle organizationGO:00069962270.036
cell morphogenesisGO:00009022890.035
enzyme linked receptor protein signaling pathwayGO:00071671060.035
epithelial tube morphogenesisGO:00605621480.034
maintenance of locationGO:005123540.034
regulation of programmed cell deathGO:00430671010.034
blood vessel developmentGO:00015682460.032
negative regulation of nitrogen compound metabolic processGO:0051172590.032
pigmentationGO:0043473850.031
organic substance biosynthetic processGO:19015762890.031
Mouse
alpha amino acid metabolic processGO:190160530.031
central nervous system developmentGO:00074173870.030
regulation of cellular biosynthetic processGO:00313262450.030
dopamine metabolic processGO:004241720.030
regulation of synaptic plasticityGO:004816710.030
positive regulation of biological processGO:00485182530.030
photoreceptor cell differentiationGO:0046530550.030
cell surface receptor signaling pathwayGO:00071663250.029
digestive tract developmentGO:00485652650.029
segmentationGO:0035282970.029
protein targeting to nucleusGO:004474430.029
cellular amine metabolic processGO:004410620.028
developmental pigmentationGO:0048066480.028
negative regulation of biological processGO:00485193040.028
blood vessel morphogenesisGO:00485142160.028
negative regulation of nucleic acid templated transcriptionGO:1903507450.028
regulation of multicellular organismal developmentGO:20000262230.028
diterpenoid metabolic processGO:0016101150.028
regulation of signalingGO:00230512350.028
regulation of cell deathGO:00109411030.028
protein metabolic processGO:00195381830.027
regulation of filopodium assemblyGO:005148920.027
regulation of response to stimulusGO:00485832690.027
heterocycle biosynthetic processGO:00181302150.027
cellular aldehyde metabolic processGO:000608140.027
regulation of bindingGO:005109830.027
negative regulation of kinase activityGO:003367340.027
appendage developmentGO:0048736800.027
cellular protein catabolic processGO:004425740.027
regulation of cell differentiationGO:00455951420.027
negative regulation of cellular processGO:00485232830.027
response to uvGO:000941130.027
small molecule metabolic processGO:0044281770.026
embryonic heart tube morphogenesisGO:00031431080.026
tissue remodelingGO:004877140.026
regulation of reproductive processGO:200024140.025
rna biosynthetic processGO:00327741810.025
organic cyclic compound biosynthetic processGO:19013622230.025
Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.025
single organism metabolic processGO:00447102170.025
Mouse
meiotic nuclear divisionGO:000712640.025
response to woundingGO:00096111160.025
nucleic acid templated transcriptionGO:00976591810.025
apoptotic processGO:00069151160.025
cell morphogenesis involved in neuron differentiationGO:00486671630.025
programmed cell deathGO:00125011190.025
amine metabolic processGO:000930820.025
cell morphogenesis involved in differentiationGO:00009041950.024
multicellular organismal response to stressGO:003355520.024
negative regulation of nucleobase containing compound metabolic processGO:0045934590.024
neuroblast proliferationGO:000740520.024
cellular aromatic compound metabolic processGO:00067252950.024
Mouse
locomotor rhythmGO:004547530.024
neurological system processGO:0050877620.024
axon developmentGO:00615641660.024
regulation of cell projection assemblyGO:006049140.024
regulation of nucleic acid templated transcriptionGO:19035062130.023
regulation of macromolecule biosynthetic processGO:00105562250.023
peptide transportGO:001583310.023
regulation of cellular macromolecule biosynthetic processGO:20001122220.023
detection of stimulusGO:0051606290.023
larval developmentGO:000216420.023
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.023
regulation of rna biosynthetic processGO:20011412130.023
immune system processGO:00023762410.023
heterocycle metabolic processGO:00464832900.023
gastrulationGO:00073692080.023
fin developmentGO:0033333770.023
transcription dna templatedGO:00063511810.022
transcription from rna polymerase ii promoterGO:0006366800.022
water homeostasisGO:003010440.022
regulation of cell developmentGO:00602841000.022
negative regulation of macromolecule metabolic processGO:0010605760.021
specification of symmetryGO:00097992040.021
hormone transportGO:000991420.021
vitamin a biosynthetic processGO:003523810.021
rna metabolic processGO:00160702190.021
chemotaxisGO:00069351040.021
nuclear transportGO:005116940.021
digestive system developmentGO:00551232890.021
nucleobase containing compound biosynthetic processGO:00346542050.021
skeletal system morphogenesisGO:00487051020.021
regulation of biosynthetic processGO:00098892500.021
regulation of signal transductionGO:00099662250.021
catecholamine metabolic processGO:000658420.021
regulation of synapse organizationGO:005080730.020
determination of left right symmetryGO:00073681790.020
hematopoietic or lymphoid organ developmentGO:00485341910.020
embryonic heart tube developmentGO:00350501330.020
single organism localizationGO:19025782250.020
single organism transportGO:00447652060.020
cell cycle arrestGO:000705010.020
regulation of stem cell proliferationGO:007209120.020
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
regulation of rna metabolic processGO:00512522240.020
regulation of cell projection organizationGO:0031344440.020
oxoacid metabolic processGO:0043436310.019
cell deathGO:00082191210.019
cellular component biogenesisGO:00440851780.019
sensory organ morphogenesisGO:00905962000.019
regulation of neurogenesisGO:0050767870.019
cellular component assembly involved in morphogenesisGO:00109271070.019
regulation of cell activationGO:005086510.019
photoreceptor cell fate specificationGO:004370410.019
cellular amino acid metabolic processGO:000652070.019
digestive tract morphogenesisGO:00485462310.018
female sex differentiationGO:004666040.018
negative regulation of rna biosynthetic processGO:1902679450.018
nucleobase containing compound metabolic processGO:00061392740.018
ubiquitin dependent protein catabolic processGO:000651130.018
embryonic hemopoiesisGO:0035162530.018
circulatory system processGO:0003013870.018
nucleocytoplasmic transportGO:000691340.018
catechol containing compound metabolic processGO:000971220.018
mesenchymal cell developmentGO:0014031780.018
regulation of dendrite developmentGO:005077330.018
diterpenoid biosynthetic processGO:001610270.018
regulation of neuron projection developmentGO:0010975400.018
fat soluble vitamin metabolic processGO:000677540.018
regulation of anatomical structure morphogenesisGO:00226031300.018
adherens junction organizationGO:003433240.018
negative regulation of metabolic processGO:0009892860.018
cellular ketone metabolic processGO:0042180110.017
protein importGO:001703830.017
determination of bilateral symmetryGO:00098552040.017
spermatid developmentGO:000728620.017
regionalizationGO:00030022740.017
protein heterooligomerizationGO:005129110.017
hindbrain developmentGO:0030902910.017
epidermal cell fate specificationGO:000995740.017
connective tissue developmentGO:0061448990.017
regulation of cellular ketone metabolic processGO:001056570.017
positive regulation of neural precursor cell proliferationGO:200017910.017
cellular component assemblyGO:00226071700.017
positive regulation of cell activationGO:005086710.017
spermatid differentiationGO:004851520.017
regulation of protein transportGO:005122330.017
negative regulation of biosynthetic processGO:0009890550.016
regulation of apoptotic processGO:0042981980.016
tube morphogenesisGO:00352393490.016
angiogenesisGO:00015251580.016
determination of heart left right asymmetryGO:00613711170.016
negative regulation of gene expressionGO:0010629650.016
carboxylic acid metabolic processGO:0019752220.016
chemosensory behaviorGO:000763510.016
heart developmentGO:00075073130.016
positive regulation of transportGO:005105020.016
modification dependent protein catabolic processGO:001994130.016
olfactory lobe developmentGO:002198840.016
retina morphogenesis in camera type eyeGO:0060042790.016
cartilage developmentGO:0051216960.016
sympathetic nervous system developmentGO:004848530.016
catecholamine biosynthetic processGO:004242320.016
positive regulation of epithelial cell proliferationGO:005067910.016
sensory perception of chemical stimulusGO:000760630.016
lipid metabolic processGO:0006629520.016
establishment of protein localization to organelleGO:007259440.016
nuclear importGO:005117030.016
macromolecular complex assemblyGO:0065003350.016
protein secretionGO:000930610.015
positive regulation of catabolic processGO:000989640.015
macromolecule biosynthetic processGO:00090592270.015
meiotic cell cycle processGO:190304630.015
cell proliferationGO:0008283800.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.015
negative regulation of transcription dna templatedGO:0045892450.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
morphogenesis of an epithelial foldGO:006057110.015
organelle assemblyGO:00709251100.015
negative regulation of cell deathGO:0060548600.015
myeloid cell differentiationGO:0030099860.015
regulation of neuronal synaptic plasticityGO:004816810.015
response to corticosteroidGO:003196010.015
regulation of dendrite morphogenesisGO:004881430.015
positive regulation of cellular processGO:00485222010.015
anterior posterior pattern specificationGO:00099521520.015
melanin metabolic processGO:000658220.015
Mouse
cellular protein metabolic processGO:00442671290.015
regulation of cell shapeGO:000836010.015
organic cyclic compound metabolic processGO:19013603010.014
Mouse
retinal metabolic processGO:004257430.014
regulation of cellular amino acid metabolic processGO:000652100.014
photoreceptor cell developmentGO:0042461400.014
proteolysis involved in cellular protein catabolic processGO:005160330.014
response to glucoseGO:000974930.014
response to carbohydrateGO:000974330.014
sensory system developmentGO:0048880760.014
cell migrationGO:00164772370.014
regulation of developmental processGO:00507932470.014
hepaticobiliary system developmentGO:0061008980.014
oocyte anterior posterior axis specificationGO:000731440.014
regulation of protein complex assemblyGO:004325430.014
carbohydrate homeostasisGO:003350010.014
protein acylationGO:004354330.014
ameboidal type cell migrationGO:00016671430.014
axon ensheathment in central nervous systemGO:003229120.014
negative regulation of epithelial cell proliferationGO:005068010.014
single organism organelle organizationGO:19025891990.014
exocytosisGO:000688710.014
immune system developmentGO:00025201910.013
regulation of hormone secretionGO:004688320.013
neural retina developmentGO:0003407490.013
localization of cellGO:00516742440.013
agingGO:000756820.013
pectoral fin morphogenesisGO:0035138290.013
g1 s transition of mitotic cell cycleGO:000008210.013
cellular macromolecule biosynthetic processGO:00346452240.013
protein localization to plasma membraneGO:007265910.013
retinoid metabolic processGO:0001523150.013
cellular amino acid biosynthetic processGO:000865220.013
response to radiationGO:0009314510.013
response to abiotic stimulusGO:00096281220.013
negative regulation of cellular metabolic processGO:0031324770.013
hormone secretionGO:004687920.013
regulation of multicellular organismal processGO:00512392770.013
cellular component disassemblyGO:002241110.013
proteasomal protein catabolic processGO:001049820.013
synaptic vesicle transportGO:004848910.013
pectoral fin developmentGO:0033339500.013
neural crest cell differentiationGO:0014033720.013
heart loopingGO:0001947940.013
lateral line ganglion developmentGO:004889020.013
modification dependent macromolecule catabolic processGO:004363230.013
stem cell differentiationGO:00488631170.013
morphogenesis of an epitheliumGO:00020093330.013
regulation of nervous system developmentGO:0051960900.013
lateral line system developmentGO:0048925760.013
cytoplasm organizationGO:000702840.013
stem cell developmentGO:0048864820.013
hatching gland developmentGO:004878530.013
regulation of cell matrix adhesionGO:000195210.012
blood circulationGO:0008015870.012
rna localizationGO:000640340.012
oxidation reduction processGO:0055114410.012
membrane invaginationGO:001032410.012
regulation of glial cell differentiationGO:004568540.012
terpenoid metabolic processGO:0006721150.012
eye photoreceptor cell differentiationGO:0001754450.012
protein localization to nucleusGO:003450430.012
establishment of localizationGO:00512342440.012
positive regulation of secretion by cellGO:190353210.012
regulation of erk1 and erk2 cascadeGO:007037240.012
response to nutrientGO:000758430.012
mesoderm developmentGO:0007498880.012
organic acid metabolic processGO:0006082310.012
wound healingGO:0042060900.012
isoprenoid metabolic processGO:0006720150.012
somatic muscle developmentGO:000752540.012
olfactory bulb developmentGO:002177240.012
rhythmic processGO:0048511210.012
response to vitaminGO:003327330.012
regulation of intracellular protein transportGO:003315730.012
proepicardium developmentGO:000334240.012
pole plasm assemblyGO:000731540.012
embryonic cranial skeleton morphogenesisGO:0048701900.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
stem cell maintenanceGO:001982740.012
lamellipodium organizationGO:009758110.012
central nervous system myelinationGO:002201020.012
septum transversum developmentGO:000334340.012
cell projection assemblyGO:0030031640.011
embryonic skeletal system developmentGO:0048706970.011
maternal determination of anterior posterior axis embryoGO:000835840.011
positive regulation of cell cycleGO:004578730.011
medulla oblongata developmentGO:002155040.011
multi organism processGO:00517041340.011
cellular response to radiationGO:007147840.011
basement membrane assemblyGO:007083130.011
striated muscle cell developmentGO:00550021080.011
diencephalon developmentGO:0021536580.011
central nervous system myelin formationGO:003228910.011
regulation of cellular amine metabolic processGO:003323800.011
cellular lipid metabolic processGO:0044255360.011
glial cell migrationGO:000834730.011
erk1 and erk2 cascadeGO:007037140.011
mitochondrion organizationGO:000700540.011
appendage morphogenesisGO:0035107560.011
neural precursor cell proliferationGO:0061351200.011
tissue regenerationGO:0042246740.011
adult behaviorGO:003053420.011
peptidyl serine modificationGO:001820920.011
positive regulation of cellular component biogenesisGO:004408930.011
protein modification processGO:00362111000.011
response to hexoseGO:000974630.011
regulation of cytoplasmic transportGO:190364940.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
regulation of behaviorGO:0050795240.011
protein polymerizationGO:005125840.011
single organismal cell cell adhesionGO:0016337290.011
hemopoiesisGO:00300971830.010
myelin assemblyGO:003228810.010
pigment cell differentiationGO:0050931380.010
regulation of meiotic cell cycleGO:005144510.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.010
cellular response to external stimulusGO:007149620.010
negative regulation of response to stimulusGO:00485851040.010
synaptic growth at neuromuscular junctionGO:005112420.010
regulation of protein targetingGO:190353320.010
gtp metabolic processGO:004603940.010
urogenital system developmentGO:0001655970.010
negative regulation of macromolecule biosynthetic processGO:0010558480.010
peptidyl lysine acetylationGO:001839420.010
meiotic chromosome segregationGO:004513230.010
cellular response to light stimulusGO:007148240.010
positive regulation of cellular catabolic processGO:003133130.010
peptidyl threonine phosphorylationGO:001810710.010
response to oxygen containing compoundGO:1901700550.010
cellular response to extracellular stimulusGO:003166820.010
glial cell differentiationGO:0010001420.010
atp catabolic processGO:000620040.010
gland developmentGO:00487321430.010
regulation of establishment of protein localizationGO:007020140.010
regulation of circadian rhythmGO:004275240.010

pmelb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.067
musculoskeletal system diseaseDOID:1700.054
disease of metabolismDOID:001466700.026
connective tissue diseaseDOID:6500.021
bone diseaseDOID:008000100.021
retinitis pigmentosaDOID:1058400.017
nervous system diseaseDOID:86300.017
eye diseaseDOID:561400.017
sensory system diseaseDOID:005015500.017
retinal diseaseDOID:567900.017
retinal degenerationDOID:846600.017
eye and adnexa diseaseDOID:149200.017
inherited metabolic disorderDOID:65500.015
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011