Danio rerio

46 known processes

atp2a2a

ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a

(Aliases: MGC55380,zgc:55380,atp2a2)

atp2a2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
heart developmentGO:00075073130.919
cardiac muscle cell developmentGO:0055013200.623
cardiac muscle tissue developmentGO:0048738480.597
striated muscle cell differentiationGO:00511461290.560
Worm
myofibril assemblyGO:0030239480.545
Worm
determination of heart left right asymmetryGO:00613711170.481
cellular component morphogenesisGO:00329893360.447
Worm
embryonic organ developmentGO:00485683810.445
larval developmentGO:000216420.441
Worm
heart contractionGO:0060047710.433
muscle contractionGO:0006936180.428
Human Zebrafish Rat
nucleoside monophosphate catabolic processGO:000912540.405
Human Mouse Rat Worm Fly
actomyosin structure organizationGO:0031032530.384
Worm
muscle cell developmentGO:00550011150.377
Worm
sarcomere organizationGO:0045214260.366
heart morphogenesisGO:00030071560.358
regulation of muscle contractionGO:000693730.348
Human Zebrafish Rat
single organism organelle organizationGO:19025891990.338
Worm
muscle structure developmentGO:00610611960.330
Worm
cellular component assembly involved in morphogenesisGO:00109271070.325
Worm
striated muscle tissue developmentGO:00147061100.321
ventricular cardiac muscle cell developmentGO:005501550.296
heart loopingGO:0001947940.291
cardiac chamber formationGO:000320740.280
cardiac atrium morphogenesisGO:000320920.268
system processGO:00030081850.268
ventricular cardiac muscle cell differentiationGO:005501260.258
cellular component biogenesisGO:00440851780.257
Worm
muscle tissue developmentGO:00605371100.253
ventricular cardiac muscle tissue morphogenesisGO:005501020.244
heart field specificationGO:000312810.243
regulation of system processGO:0044057400.241
circulatory system processGO:0003013870.239
embryonic heart tube morphogenesisGO:00031431080.237
regulation of heart contractionGO:0008016320.231
actin filament based processGO:0030029640.231
Worm
blood circulationGO:0008015870.230
muscle cell differentiationGO:00426921390.219
Worm
embryo development ending in birth or egg hatchingGO:00097922710.213
Worm
cardiac muscle cell differentiationGO:0055007300.210
regulation of blood circulationGO:1903522320.178
embryonic heart tube developmentGO:00350501330.178
cytoskeleton organizationGO:0007010960.177
Worm
ventricular cardiac muscle tissue developmentGO:000322930.171
cardiac cell developmentGO:0055006210.158
organelle assemblyGO:00709251100.154
Worm
agingGO:000756820.145
Worm
negative regulation of heart contractionGO:004582220.144
Mouse
cardiac conduction system developmentGO:000316110.138
actin filament based movementGO:003004810.136
regulation of nucleobase containing compound metabolic processGO:00192192500.135
Fly
striated muscle cell developmentGO:00550021080.135
Worm
cell projection organizationGO:00300302840.116
cardiac ventricle formationGO:000321110.114
transmembrane transportGO:00550851200.114
Human Mouse Rat Worm Fly
actin cytoskeleton organizationGO:0030036630.110
Worm
ribonucleoside monophosphate catabolic processGO:000915840.105
Human Mouse Rat Worm Fly
heart joggingGO:0003146400.102
metal ion transportGO:0030001580.101
Human Mouse Rat Worm Fly
purine ribonucleoside monophosphate catabolic processGO:000916940.100
Human Mouse Rat Worm Fly
muscle system processGO:0003012200.097
Human Zebrafish Mouse Rat
cation homeostasisGO:0055080330.093
Human Zebrafish Mouse Worm Fly
regulation of ion transmembrane transporter activityGO:003241220.092
Fly
homeostatic processGO:00425921420.091
Human Zebrafish Mouse Worm Fly
regulation of macromolecule metabolic processGO:00602553170.089
atrial cardiac muscle cell developmentGO:005501440.087
specification of symmetryGO:00097992040.086
digestive tract developmentGO:00485652650.086
cellular component assemblyGO:00226071700.085
Worm
positive regulation of heart contractionGO:004582320.085
regulation of cellular metabolic processGO:00313233200.080
Fly
heart processGO:0003015710.080
somitogenesisGO:0001756870.079
somite developmentGO:0061053960.079
establishment of localizationGO:00512342440.078
Human Mouse Rat Worm Fly
determination of bilateral symmetryGO:00098552040.077
divalent metal ion transportGO:0070838200.077
Human Mouse Rat Worm Fly
regulation of cardiac muscle tissue developmentGO:005502410.076
cardiocyte differentiationGO:0035051440.075
striated muscle contractionGO:0006941120.075
Human Rat
nitrogen compound metabolic processGO:00068073190.073
Human Mouse Rat Worm Fly
tube morphogenesisGO:00352393490.071
response to stressGO:00069502630.071
Worm
regulation of multicellular organismal processGO:00512392770.070
negative regulation of striated muscle tissue developmentGO:004584320.068
central nervous system developmentGO:00074173870.066
positive regulation of blood circulationGO:190352420.065
cell migration involved in heart developmentGO:0060973220.061
morphogenesis of an epitheliumGO:00020093330.061
positive regulation of transportGO:005105020.058
Fly
regulation of nucleoside metabolic processGO:000911820.058
Fly
sensory organ developmentGO:00074233930.058
cardiac atrium developmentGO:000323040.055
regulation of transmembrane transporter activityGO:002289820.055
Fly
regulation of nitrogen compound metabolic processGO:00511712510.053
Fly
positive regulation of biological processGO:00485182530.053
Fly
cytokinesisGO:000091030.052
regulation of metabolic processGO:00192223590.052
Fly
post embryonic morphogenesisGO:000988640.052
cardiac chamber morphogenesisGO:0003206120.052
transportGO:00068102200.052
Human Mouse Rat Worm Fly
inorganic cation transmembrane transportGO:0098662500.051
Human Mouse Rat Worm Fly
epithelial tube morphogenesisGO:00605621480.051
response to external stimulusGO:00096052640.050
Zebrafish Worm
divalent inorganic cation homeostasisGO:0072507220.050
Human Zebrafish Mouse Worm Fly
ion homeostasisGO:0050801410.049
Human Zebrafish Mouse Worm Fly
pyruvate metabolic processGO:000609010.048
neuron differentiationGO:00301823530.048
cellular macromolecule metabolic processGO:00442603910.047
calcium ion homeostasisGO:0055074190.046
Human Zebrafish Mouse Worm Fly
carbohydrate derivative metabolic processGO:1901135610.046
Human Mouse Rat Worm Fly
cell morphogenesis involved in neuron differentiationGO:00486671630.045
brain developmentGO:00074202930.045
cell cycle g1 s phase transitionGO:004484310.045
synaptic growth at neuromuscular junctionGO:005112420.045
nucleocytoplasmic transportGO:000691340.045
regulation of membrane potentialGO:0042391230.044
Rat Fly
locomotor rhythmGO:004547530.043
regulation of developmental processGO:00507932470.043
heart valve formationGO:000318840.043
cell part morphogenesisGO:00329902460.043
cellular nitrogen compound biosynthetic processGO:00442712180.042
regulation of purine nucleotide catabolic processGO:003312120.042
Fly
gene expressionGO:00104672520.042
protein targeting to nucleusGO:004474430.040
developmental growthGO:00485891660.040
nucleobase containing compound metabolic processGO:00061392740.040
Human Mouse Rat Worm Fly
negative regulation of biological processGO:00485193040.040
Zebrafish Mouse
regulation of biosynthetic processGO:00098892500.040
neurotransmitter transportGO:000683620.040
Mouse
regulation of heart rateGO:000202750.040
cation transmembrane transportGO:0098655650.039
Human Mouse Rat Worm Fly
multicellular organism growthGO:003526440.038
pharyngeal muscle developmentGO:004328240.038
ventricular cardiac myofibril assemblyGO:005500540.038
cellular nitrogen compound metabolic processGO:00346412900.037
Human Mouse Rat Worm Fly
heterocycle metabolic processGO:00464832900.037
Human Mouse Rat Worm Fly
regulation of multicellular organism growthGO:004001440.037
nucleic acid metabolic processGO:00903042440.037
cellular response to nutrient levelsGO:003166920.037
organelle organizationGO:00069962270.036
Worm
adult behaviorGO:003053420.036
Fly
cell morphogenesisGO:00009022890.035
rna metabolic processGO:00160702190.035
monovalent inorganic cation transportGO:0015672420.035
regulation of nucleotide catabolic processGO:003081120.034
Fly
regulation of tube sizeGO:003515020.034
regulation of blood pressureGO:000821710.034
regulation of metal ion transportGO:001095940.033
Fly
negative regulation of metabolic processGO:0009892860.033
regulation of gene expressionGO:00104682650.033
plasma membrane repairGO:000177820.033
g1 s transition of mitotic cell cycleGO:000008210.032
axon developmentGO:00615641660.032
determination of left right symmetryGO:00073681790.032
ion transmembrane transportGO:0034220910.032
Human Mouse Rat Worm Fly
regulation of cytoplasmic transportGO:190364940.032
purine nucleoside monophosphate catabolic processGO:000912840.032
Human Mouse Rat Worm Fly
cardiac ventricle morphogenesisGO:000320870.032
chordate embryonic developmentGO:00430092710.031
regulation of biological qualityGO:00650082630.031
Human Zebrafish Mouse Rat Worm Fly
regulation of organ growthGO:004662030.031
smooth muscle contractionGO:000693920.031
intestinal cholesterol absorptionGO:003029920.031
renal system developmentGO:0072001940.031
nuclear transportGO:005116940.031
eye developmentGO:00016542770.030
immune responseGO:0006955280.030
protein import into nucleusGO:000660630.030
membrane repolarizationGO:008600920.030
response to virusGO:0009615210.030
embryonic organ morphogenesisGO:00485622740.030
metal ion homeostasisGO:0055065260.030
Human Zebrafish Mouse Worm Fly
cellular aromatic compound metabolic processGO:00067252950.029
Human Mouse Rat Worm Fly
protein importGO:001703830.029
regulation of cellular macromolecule biosynthetic processGO:20001122220.029
regulation of epithelial cell proliferationGO:005067830.029
ion transportGO:00068111140.029
Human Mouse Rat Worm Fly
signal transductionGO:00071654550.029
Human Mouse Rat Worm
cell proliferation involved in heart morphogenesisGO:006132320.028
regulation of cellular biosynthetic processGO:00313262450.028
atrioventricular valve formationGO:000319030.028
limb bud formationGO:006017420.028
sodium ion transportGO:0006814240.028
g2 m transition of mitotic cell cycleGO:000008640.028
antimicrobial humoral responseGO:001973020.027
neuron projection developmentGO:00311751800.027
locomotionGO:00400113130.027
single organism localizationGO:19025782250.027
Human Mouse Rat Worm Fly
regulation of protein targetingGO:190353320.026
cardiac myofibril assemblyGO:005500390.026
regulation of transporter activityGO:003240920.026
Fly
intracellular transportGO:0046907320.026
Rat
actin mediated cell contractionGO:007025210.026
growthGO:00400071740.025
regulation of stem cell proliferationGO:007209120.025
anatomical structure homeostasisGO:0060249360.025
cytoskeleton dependent cytokinesisGO:006164030.025
protein metabolic processGO:00195381830.025
atrial ventricular junction remodelingGO:000329420.025
inorganic ion transmembrane transportGO:0098660570.025
Human Mouse Rat Worm Fly
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.025
cardiac muscle contractionGO:006004860.025
Human Rat
fluid transportGO:0042044170.025
reproductionGO:0000003400.024
Worm
maintenance of locationGO:005123540.024
Fly
regulation of skeletal muscle tissue developmentGO:004864140.024
establishment of protein localization to organelleGO:007259440.024
regulation of primary metabolic processGO:00800903110.024
Fly
taxisGO:00423301090.024
cellular response to fluid shear stressGO:007149810.024
response to organic cyclic compoundGO:0014070510.023
deathGO:00162651210.023
Worm
regulation of skeletal muscle cell differentiationGO:200101410.023
negative regulation of protein phosphorylationGO:000193340.023
heterocycle biosynthetic processGO:00181302150.023
behaviorGO:0007610740.023
Fly
sensory organ morphogenesisGO:00905962000.023
cell projection assemblyGO:0030031640.023
somatic muscle developmentGO:000752540.023
glucocorticoid biosynthetic processGO:000670410.023
carbohydrate derivative biosynthetic processGO:1901137430.023
positive regulation of cytosolic calcium ion concentrationGO:000720440.022
organonitrogen compound metabolic processGO:1901564740.022
Human Mouse Rat Worm Fly
organophosphate metabolic processGO:0019637370.022
Human Mouse Rat Worm Fly
cell motilityGO:00488702440.022
nucleic acid templated transcriptionGO:00976591810.022
immune system processGO:00023762410.021
skeletal myofibril assemblyGO:001486670.021
glucocorticoid metabolic processGO:000821120.021
skeletal muscle organ developmentGO:0060538780.020
intestinal absorptionGO:005089220.020
cellular component movementGO:00069283350.020
cardiac ventricle developmentGO:000323190.020
regulation of actin filament based processGO:003297090.020
Rat
neuron developmentGO:00486662620.020
cellular ion homeostasisGO:0006873170.020
Human Zebrafish Mouse Worm Fly
muscle cell fate determinationGO:000752110.020
regulation of protein complex assemblyGO:004325430.019
innate immune responseGO:0045087130.019
regulation of myotube differentiationGO:001083020.019
regulation of anatomical structure morphogenesisGO:00226031300.019
digestive system developmentGO:00551232890.019
cellular response to external stimulusGO:007149620.019
regulation of cardiac muscle contractionGO:005511720.019
Human Rat
cell migrationGO:00164772370.019
positive regulation of striated muscle cell differentiationGO:005115510.019
regulation of nucleocytoplasmic transportGO:004682220.018
negative regulation of cellular processGO:00485232830.018
segmentationGO:0035282970.018
meiotic nuclear divisionGO:000712640.018
regulation of macromolecule biosynthetic processGO:00105562250.018
cardiac muscle tissue morphogenesisGO:005500870.018
lipid storageGO:001991510.018
Fly
organic cyclic compound metabolic processGO:19013603010.018
Human Mouse Rat Worm Fly
cellular homeostasisGO:0019725260.018
Human Zebrafish Mouse Worm Fly
regulation of programmed cell deathGO:00430671010.018
directional locomotionGO:003305810.018
small molecule metabolic processGO:0044281770.018
Human Mouse Rat Worm Fly
hormone secretionGO:004687920.018
regulation of apoptotic processGO:0042981980.018
negative regulation of muscle tissue developmentGO:190186220.018
response to biotic stimulusGO:0009607970.017
regulation of cardiac muscle cell differentiationGO:200072510.017
regulation of sodium ion transportGO:000202820.017
positive regulation of muscle cell differentiationGO:005114910.017
anterior posterior pattern specificationGO:00099521520.017
axonogenesisGO:00074091520.017
cilium assemblyGO:0042384580.017
regulation of intracellular protein transportGO:003315730.017
regulation of synapse organizationGO:005080730.017
protein localization to nucleusGO:003450430.017
response to corticosteroidGO:003196010.017
muscle organ morphogenesisGO:004864480.017
startle responseGO:000196440.017
endocardial cushion morphogenesisGO:000320330.017
ribonucleoside triphosphate biosynthetic processGO:000920120.017
regulation of sodium ion transmembrane transporter activityGO:200064910.016
regulation of heart morphogenesisGO:2000826170.016
positive regulation of striated muscle tissue developmentGO:004584410.016
response to chemicalGO:00422213200.016
Rat Worm
angiogenesisGO:00015251580.016
regulation of synapse assemblyGO:005196330.016
specification of organ positionGO:001015930.016
regulation of bone mineralizationGO:003050020.016
nuclear importGO:005117030.016
response to endogenous stimulusGO:0009719830.016
Rat
regulation of biomineral tissue developmentGO:007016720.016
negative regulation of response to stimulusGO:00485851040.016
ribonucleotide biosynthetic processGO:0009260200.016
positive regulation of skeletal muscle tissue developmentGO:004864310.016
regulation of heart growthGO:006042020.016
regulation of protein bindingGO:004339330.016
mitochondrial transportGO:000683920.016
intermediate mesoderm developmentGO:004838920.015
organic substance biosynthetic processGO:19015762890.015
Fly
regulation of protein import into nucleusGO:004230620.015
specification of organ axis polarityGO:001008420.015
cell projection morphogenesisGO:00488582440.015
regulation of hydrolase activityGO:0051336280.015
Fly
generation of neuronsGO:00486993850.015
regionalizationGO:00030022740.015
apoptotic processGO:00069151160.015
Worm
regulation of skeletal muscle fiber developmentGO:004874220.015
single organism transportGO:00447652060.015
Human Mouse Rat Worm Fly
smad protein complex assemblyGO:000718310.014
cilium morphogenesisGO:0060271850.014
inner ear developmentGO:00488391260.014
cellular response to hormone stimulusGO:0032870390.014
cardiac muscle fiber developmentGO:004873930.014
response to carbohydrateGO:000974330.014
regulation of actin filament based movementGO:190311510.014
Rat
positive regulation of epithelial cell proliferationGO:005067910.014
divalent inorganic cation transportGO:0072511210.014
Human Mouse Rat Worm Fly
apical junction assemblyGO:004329710.014
purine nucleotide metabolic processGO:0006163270.014
Human Mouse Rat Worm Fly
cellular response to endogenous stimulusGO:0071495680.014
organic cyclic compound biosynthetic processGO:19013622230.014
purine ribonucleoside biosynthetic processGO:004612920.014
response to glucocorticoidGO:005138410.014
regulation of bmp signaling pathway involved in heart joggingGO:2000223120.014
regulation of blood vessel sizeGO:005088020.014
regulation of n methyl d aspartate selective glutamate receptor activityGO:200031010.014
regulation of reproductive processGO:200024140.014
specification of axis polarityGO:006500140.014
response to fluid shear stressGO:003440520.014
regulation of ion transportGO:0043269220.014
Fly
rna biosynthetic processGO:00327741810.013
neurotransmitter secretionGO:000726920.013
Mouse
regulation of striated muscle contractionGO:000694220.013
Human Rat
atrial cardiac myofibril assemblyGO:005500420.013
regulation of rna metabolic processGO:00512522240.013
mitochondrion organizationGO:000700540.013
cell substrate adhesionGO:003158940.013
cell death in response to oxidative stressGO:003647320.013
regulation of cell activationGO:005086510.013
regulation of glutamate receptor signaling pathwayGO:190044910.013
positive regulation of cellular component biogenesisGO:004408930.013
response to lipidGO:0033993600.013
sequestering of metal ionGO:005123830.013
Fly
regulation of cytokine productionGO:000181730.013
programmed cell deathGO:00125011190.013
Worm
muscle organ developmentGO:00075171010.013
cardiac muscle cell contractionGO:008600310.013
purine ribonucleoside triphosphate biosynthetic processGO:000920620.013
b cell activationGO:004211320.013
establishment of localization in cellGO:0051649770.013
Mouse Rat
regulation of cardiac muscle cell contractionGO:008600410.012
Rat
regenerationGO:0031099910.012
regulation of sequestering of calcium ionGO:005128240.012
Fly
cell surface receptor signaling pathwayGO:00071663250.012
cellular protein metabolic processGO:00442671290.012
otic vesicle morphogenesisGO:0071600340.012
single organism metabolic processGO:00447102170.012
Human Mouse Rat Worm Fly
regulation of synaptic plasticityGO:004816710.012
pharynx developmentGO:006046550.012
cellular response to organic cyclic compoundGO:0071407380.012
calcium ion importGO:007050940.012
Rat Worm
regulation of rna biosynthetic processGO:20011412130.012
cellular response to starvationGO:000926710.012
outflow tract morphogenesisGO:000315110.012
regulation of cellular component movementGO:0051270550.012
Rat
cell matrix adhesionGO:000716040.012
monocyte differentiationGO:003022420.012
extracellular structure organizationGO:0043062270.012
regulation of cell deathGO:00109411030.012
regulation of molecular functionGO:0065009700.012
Fly
regulation of sarcomere organizationGO:006029720.012
ear developmentGO:00435831270.012
mesenchymal cell differentiationGO:0048762870.012
macromolecule biosynthetic processGO:00090592270.012
neural crest cell differentiationGO:0014033720.012
production of molecular mediator of immune responseGO:000244020.012
rna transportGO:005065820.012
endocrine system developmentGO:0035270650.012
lipid digestionGO:004424130.012
positive regulation of gene expressionGO:0010628710.012
nucleobase containing compound biosynthetic processGO:00346542050.012
cellular response to chemical stimulusGO:00708871570.012
Worm
positive regulation of muscle organ developmentGO:004863610.012
camera type eye developmentGO:00430102220.011
neural tube patterningGO:0021532330.011
transcription dna templatedGO:00063511810.011
cellular response to extracellular stimulusGO:003166820.011
heart valve developmentGO:0003170140.011
regulation of dna templated transcription in response to stressGO:004362000.011
aromatic compound biosynthetic processGO:00194382170.011
rostrocaudal neural tube patterningGO:0021903290.011
negative regulation of protein complex assemblyGO:003133310.011
erythrocyte differentiationGO:0030218540.011
endocardial cushion formationGO:000327220.011
regulation of dna templated transcription elongationGO:003278430.011
rna localizationGO:000640340.011
inner ear morphogenesisGO:0042472630.011
extracellular matrix organizationGO:0030198270.011
calcium ion transport into cytosolGO:006040230.011
regulation of cell communicationGO:00106462320.011
Mouse
head developmentGO:00603223030.011
positive regulation of muscle tissue developmentGO:190186310.011
response to temperature stimulusGO:0009266150.011
response to abiotic stimulusGO:00096281220.011
Zebrafish
regulation of protein transportGO:005122330.011
positive regulation of cellular processGO:00485222010.011
Fly
cranial suture morphogenesisGO:006036310.011
axis specificationGO:0009798430.011
camera type eye morphogenesisGO:00485931080.011
cell migration involved in heart formationGO:0060974100.011
catabolic processGO:0009056320.011
Human Mouse Rat Worm Fly
regulation of mesenchymal cell proliferationGO:001046410.011
positive regulation of cellular biosynthetic processGO:0031328680.011
organic acid metabolic processGO:0006082310.011
Fly
inositol lipid mediated signalingGO:004801720.011
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.010
gtp catabolic processGO:000618420.010
cardiac chamber developmentGO:0003205190.010
skeletal muscle tissue developmentGO:0007519670.010
cellular protein complex assemblyGO:0043623190.010
Worm
epithelial cell differentiationGO:00308551160.010
regulation of cardiac chamber morphogenesisGO:190121920.010
cellular sodium ion homeostasisGO:000688310.010
regulation of cellular protein metabolic processGO:0032268520.010
cellular metal ion homeostasisGO:0006875160.010
Human Zebrafish Mouse Worm Fly
regulation of cellular amino acid metabolic processGO:000652100.010
regulation of peptidyl tyrosine phosphorylationGO:005073010.010
developmental growth involved in morphogenesisGO:0060560860.010
regulation of response to stimulusGO:00485832690.010
Mouse

atp2a2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.711
cardiovascular system diseaseDOID:128700.711
intrinsic cardiomyopathyDOID:006003600.711
disease of anatomical entityDOID:700.711
Human
cardiomyopathyDOID:005070000.711
heart diseaseDOID:11400.711
muscular diseaseDOID:008000000.711
myopathyDOID:42300.711
muscle tissue diseaseDOID:6600.711
hypertrophic cardiomyopathyDOID:1198400.033
dilated cardiomyopathyDOID:1293000.022