Danio rerio

31 known processes

brca2

breast cancer 2, early onset

(Aliases: fancd1)

brca2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oocyte anterior posterior axis specificationGO:000731440.669
oocyte differentiationGO:0009994140.649
sexual reproductionGO:0019953360.649
anterior posterior pattern specificationGO:00099521520.579
germ cell developmentGO:0007281220.567
gamete generationGO:0007276330.539
nucleic acid metabolic processGO:00903042440.520
pole plasm assemblyGO:000731540.512
segmentationGO:0035282970.507
cellular process involved in reproduction in multicellular organismGO:0022412280.462
negative regulation of dna recombinationGO:004591020.437
oocyte axis specificationGO:000730950.411
meiotic chromosome segregationGO:004513230.404
oocyte developmentGO:0048599140.368
chromosome organizationGO:0051276310.362
regionalizationGO:00030022740.334
cellular macromolecule metabolic processGO:00442603910.326
single organism metabolic processGO:00447102170.298
organic cyclic compound metabolic processGO:19013603010.294
germ line stem cell divisionGO:004207810.284
cellular aromatic compound metabolic processGO:00067252950.279
multicellular organism reproductionGO:0032504350.278
oocyte constructionGO:000730850.250
nucleobase containing compound metabolic processGO:00061392740.250
meiosis iGO:000712710.245
developmental process involved in reproductionGO:0003006270.241
spermatid developmentGO:000728620.237
multicellular organismal reproductive processGO:0048609350.236
single organism organelle organizationGO:19025891990.231
regulation of dna recombinationGO:000001820.226
maternal determination of anterior posterior axis embryoGO:000835840.219
macromolecule biosynthetic processGO:00090592270.215
spermatid differentiationGO:004851520.207
cellular response to dna damage stimulusGO:0006974240.203
meiotic cell cycle processGO:190304630.161
female gamete generationGO:0007292140.158
anterior posterior axis specificationGO:0009948200.148
rna metabolic processGO:00160702190.147
nucleoside monophosphate catabolic processGO:000912540.139
oocyte maturationGO:000155640.137
cellular biosynthetic processGO:00442492860.137
nitrogen compound metabolic processGO:00068073190.132
response to stressGO:00069502630.131
single organism reproductive processGO:0044702400.131
synapsisGO:000712910.130
cellular macromolecule biosynthetic processGO:00346452240.129
dna biosynthetic processGO:007189730.125
regulation of metabolic processGO:00192223590.123
regulation of nucleobase containing compound metabolic processGO:00192192500.123
spermatogenesisGO:000728370.120
sensory organ morphogenesisGO:00905962000.120
cellular nitrogen compound metabolic processGO:00346412900.119
multi organism processGO:00517041340.119
centrosome organizationGO:005129710.119
cytoplasm organizationGO:000702840.117
chromosome organization involved in meiosisGO:007019210.117
biosynthetic processGO:00090582940.114
reproductionGO:0000003400.112
regulation of cellular biosynthetic processGO:00313262450.108
regulation of cell maturationGO:190342910.107
cell cycle g2 m phase transitionGO:004483940.102
nucleobase containing compound biosynthetic processGO:00346542050.101
stem cell divisionGO:001714510.098
regulation of nitrogen compound metabolic processGO:00511712510.097
regulation of cellular metabolic processGO:00313233200.093
regulation of macromolecule metabolic processGO:00602553170.091
positive regulation of mrna metabolic processGO:190331320.091
eye developmentGO:00016542770.087
heterocycle metabolic processGO:00464832900.087
regulation of mrna catabolic processGO:006101330.086
microtubule cytoskeleton organizationGO:0000226330.084
regulation of mrna processingGO:005068430.082
intracellular mrna localizationGO:000829810.081
stem cell maintenanceGO:001982740.081
dna metabolic processGO:0006259270.080
female meiotic divisionGO:000714320.080
axis specificationGO:0009798430.079
cellular component assemblyGO:00226071700.078
multi organism reproductive processGO:0044703360.077
anterior posterior axis specification embryoGO:000859550.077
development of primary female sexual characteristicsGO:004654540.076
multicellular organism growthGO:003526440.074
agingGO:000756820.073
muscle cell developmentGO:00550011150.071
purine nucleoside monophosphate catabolic processGO:000912840.070
negative regulation of biological processGO:00485193040.069
microtubule based processGO:0007017600.069
signal transductionGO:00071654550.068
regulation of nucleic acid templated transcriptionGO:19035062130.068
aromatic compound biosynthetic processGO:00194382170.067
positive regulation of mrna processingGO:005068510.067
dicarboxylic acid metabolic processGO:004364810.064
ribonucleoside monophosphate catabolic processGO:000915840.063
negative regulation of cellular processGO:00485232830.063
organelle assemblyGO:00709251100.061
female sex differentiationGO:004666040.060
blastoderm segmentationGO:000735060.059
regulation of oocyte developmentGO:006028130.059
centrosome duplicationGO:005129810.058
positive regulation of cell cycleGO:004578730.056
establishment of localization in cellGO:0051649770.054
female germ line stem cell maintenanceGO:003609910.053
germ line stem cell maintenanceGO:003071820.052
female meiosis chromosome segregationGO:001632110.052
g2 m transition of mitotic cell cycleGO:000008640.052
reciprocal meiotic recombinationGO:000713110.051
dorsal ventral pattern formationGO:00099531250.051
negative regulation of protein metabolic processGO:0051248160.050
macroautophagyGO:001623610.050
regulation of rna biosynthetic processGO:20011412130.049
cellular response to estradiol stimulusGO:007139210.049
regulation of cellular macromolecule biosynthetic processGO:20001122220.049
double strand break repairGO:000630230.049
apoptotic processGO:00069151160.048
ovarian follicle developmentGO:000154120.048
rna localizationGO:000640340.047
cell deathGO:00082191210.047
stem cell differentiationGO:00488631170.046
regulation of cell deathGO:00109411030.046
reciprocal dna recombinationGO:003582510.045
chromosome segregationGO:0007059120.045
regulation of macromolecule biosynthetic processGO:00105562250.045
negative regulation of gene expressionGO:0010629650.045
myotube cell developmentGO:0014904350.045
organelle organizationGO:00069962270.044
regulation of primary metabolic processGO:00800903110.044
reproductive processGO:0022414400.044
regulation of multicellular organism growthGO:004001440.043
ovulation cycleGO:004269820.043
cell cycle processGO:0022402530.043
organic cyclic compound biosynthetic processGO:19013622230.043
microtubule organizing center organizationGO:003102310.043
positive regulation of stem cell proliferationGO:200064810.043
blood vessel morphogenesisGO:00485142160.042
cellular localizationGO:0051641970.042
morphogenesis of an epitheliumGO:00020093330.042
embryonic axis specificationGO:0000578120.042
anatomical structure homeostasisGO:0060249360.042
negative regulation of biosynthetic processGO:0009890550.041
cell cycleGO:0007049930.041
regulation of apoptotic processGO:0042981980.041
cardiac atrium morphogenesisGO:000320920.040
protein modification processGO:00362111000.039
protein metabolic processGO:00195381830.039
maintenance of locationGO:005123540.039
positive regulation of catabolic processGO:000989640.038
muscle fiber developmentGO:0048747520.037
organic substance biosynthetic processGO:19015762890.037
pronuclear migrationGO:003504610.036
response to abiotic stimulusGO:00096281220.036
spindle assemblyGO:005122520.036
male meiosisGO:000714020.035
mitochondrion organizationGO:000700540.035
rna biosynthetic processGO:00327741810.035
dna repairGO:000628160.035
negative regulation of cell deathGO:0060548600.035
gene expressionGO:00104672520.035
cellular component movementGO:00069283350.034
regulation of multicellular organismal developmentGO:20000262230.034
heterocycle biosynthetic processGO:00181302150.034
rhythmic processGO:0048511210.033
rna catabolic processGO:000640170.033
cell migrationGO:00164772370.033
ovulation cycle processGO:002260220.032
female gonad developmentGO:000858540.032
cytoskeleton organizationGO:0007010960.032
programmed cell deathGO:00125011190.032
positive regulation of biological processGO:00485182530.032
phosphorylationGO:0016310690.032
positive regulation of striated muscle tissue developmentGO:004584410.032
cellular component biogenesisGO:00440851780.032
striated muscle cell differentiationGO:00511461290.031
atp catabolic processGO:000620040.031
embryonic organ developmentGO:00485683810.031
cell substrate adhesionGO:003158940.031
positive regulation of signal transductionGO:0009967560.031
transportGO:00068102200.030
positive regulation of cell communicationGO:0010647560.030
specification of axis polarityGO:006500140.030
locomotionGO:00400113130.030
regulation of dna catabolic processGO:190362410.030
regulation of autophagyGO:001050630.030
cellular macromolecule catabolic processGO:0044265120.030
positive regulation of neuron deathGO:190121610.029
regulation of smad protein complex assemblyGO:001099010.029
developmental maturationGO:0021700340.029
cellular protein modification processGO:00064641000.029
response to vitaminGO:003327330.029
regulation of cell differentiationGO:00455951420.029
macromolecule modificationGO:00434121110.028
cellular response to stressGO:0033554620.028
cilium morphogenesisGO:0060271850.028
meiotic nuclear divisionGO:000712640.028
somatic cell dna recombinationGO:001644410.028
erythrocyte maturationGO:004324980.028
central nervous system developmentGO:00074173870.027
rna 3 end processingGO:003112320.027
positive regulation of transportGO:005105020.027
skeletal muscle organ developmentGO:0060538780.027
transcription from rna polymerase ii promoterGO:0006366800.026
negative regulation of cellular metabolic processGO:0031324770.026
regulation of dna replicationGO:000627530.026
regulation of rna metabolic processGO:00512522240.026
insulin like growth factor receptor signaling pathwayGO:004800940.025
tripartite regional subdivisionGO:000735150.025
regulation of transcription dna templatedGO:00063552130.025
cell agingGO:000756920.025
negative regulation of macromolecule metabolic processGO:0010605760.025
catabolic processGO:0009056320.025
sister chromatid cohesionGO:000706220.024
cellular response to superoxideGO:007145120.024
regulation of cell communicationGO:00106462320.024
one carbon compound transportGO:0019755140.024
response to amphetamineGO:000197510.024
cellular nitrogen compound biosynthetic processGO:00442712180.024
mitotic dna integrity checkpointGO:004477440.024
meiosis iiGO:000713510.024
determination of heart left right asymmetryGO:00613711170.024
b cell activationGO:004211320.023
nuclear migrationGO:000709730.023
growthGO:00400071740.023
cognitionGO:005089010.023
autophagyGO:000691440.023
regulation of cellular amino acid metabolic processGO:000652100.023
cell surface receptor signaling pathwayGO:00071663250.023
brain developmentGO:00074202930.022
single organism cellular localizationGO:1902580460.022
rna processingGO:0006396250.022
chromatin modificationGO:0016568210.022
head developmentGO:00603223030.022
stem cell developmentGO:0048864820.022
regulation of protein modification by small protein conjugation or removalGO:190332030.021
macromolecule localizationGO:0033036540.021
cellular response to oxygen radicalGO:007145020.021
sensory organ developmentGO:00074233930.021
carbon dioxide transportGO:001567030.021
regulation of skeletal muscle fiber developmentGO:004874220.021
regulation of cell developmentGO:00602841000.021
mechanosensory behaviorGO:000763820.021
regulation of synaptic plasticityGO:004816710.021
embryonic organ morphogenesisGO:00485622740.021
mrna processingGO:0006397140.021
single organism transportGO:00447652060.021
cellular amine metabolic processGO:004410620.020
positive regulation of neural precursor cell proliferationGO:200017910.020
purine ribonucleoside monophosphate catabolic processGO:000916940.020
cellular protein metabolic processGO:00442671290.020
mitotic cell cycle processGO:1903047480.020
rna splicingGO:0008380160.020
regulation of gene silencing by rnaGO:006096610.020
transcription dna templatedGO:00063511810.019
cellular response to extracellular stimulusGO:003166820.019
organic acid metabolic processGO:0006082310.019
striated muscle cell developmentGO:00550021080.019
negative regulation of metabolic processGO:0009892860.019
negative regulation of programmed cell deathGO:0043069580.019
removal of superoxide radicalsGO:001943020.019
mrna metabolic processGO:0016071200.019
alpha amino acid metabolic processGO:190160530.019
centrosome cycleGO:000709810.018
larval developmentGO:000216420.018
defense response to other organismGO:0098542330.018
dna catabolic processGO:000630810.018
organism emergence from protective structureGO:007168440.018
regulation of cell sizeGO:0008361290.018
striated muscle tissue developmentGO:00147061100.018
microtubule depolymerizationGO:000701910.017
fertilizationGO:000956630.017
nucleic acid templated transcriptionGO:00976591810.017
deathGO:00162651210.017
b cell differentiationGO:003018310.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
establishment of organelle localizationGO:0051656450.017
regulation of localizationGO:00328791040.017
response to nitrogen compoundGO:1901698190.017
skeletal muscle fiber developmentGO:0048741350.017
bmp signaling pathwayGO:0030509520.017
negative regulation of translationGO:001714810.017
regulation of translational initiationGO:000644610.017
response to superoxideGO:000030320.017
somitogenesisGO:0001756870.016
mrna 3 end processingGO:003112420.016
mitotic cell cycle embryonicGO:004544820.016
cellular response to starvationGO:000926710.016
oocyte growthGO:000155510.016
non recombinational repairGO:000072620.016
notochord developmentGO:0030903540.016
endosomal transportGO:001619720.016
organelle localizationGO:0051640490.016
immune system processGO:00023762410.016
oogenesisGO:0048477140.016
smad protein complex assemblyGO:000718310.016
regulation of mrna metabolic processGO:190331160.016
regulation of nucleoside metabolic processGO:000911820.015
chromatin organizationGO:0006325220.015
neuroblast fate commitmentGO:001401710.015
heart valve formationGO:000318840.015
behaviorGO:0007610740.015
mitotic dna damage checkpointGO:004477340.015
positive regulation of cellular processGO:00485222010.015
negative regulation of cell differentiationGO:0045596460.015
regulation of signalingGO:00230512350.015
cellular response to organic cyclic compoundGO:0071407380.015
regulation of transmembrane transporter activityGO:002289820.015
single organism localizationGO:19025782250.015
mrna polyadenylationGO:000637820.015
epithelial tube morphogenesisGO:00605621480.015
regulation of protein transportGO:005122330.015
dna templated transcription initiationGO:000635210.015
translational initiationGO:000641330.014
urogenital system developmentGO:0001655970.014
cell migration involved in gastrulationGO:0042074790.014
cellular response to hypoxiaGO:007145610.014
organelle fissionGO:0048285230.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
regulation of bindingGO:005109830.014
mitotic sister chromatid segregationGO:000007060.014
production of small rna involved in gene silencing by rnaGO:007091810.014
glycoprotein metabolic processGO:0009100230.014
gas transportGO:001566930.014
single organism biosynthetic processGO:0044711710.014
regulation of biosynthetic processGO:00098892500.014
regulation of myotube differentiationGO:001083020.014
carbohydrate derivative biosynthetic processGO:1901137430.013
myotube differentiationGO:0014902450.013
production of molecular mediator of immune responseGO:000244020.013
developmental growthGO:00485891660.013
embryonic digestive tract developmentGO:004856640.013
response to corticosteroidGO:003196010.013
histone phosphorylationGO:001657220.013
regulation of nuclease activityGO:003206910.013
nuclear transportGO:005116940.013
positive regulation of erk1 and erk2 cascadeGO:007037420.013
cell maturationGO:0048469230.013
regulation of wound healingGO:006104120.013
reactive oxygen species biosynthetic processGO:190340910.013
nuclear transcribed mrna catabolic processGO:000095640.013
regulation of cellular protein metabolic processGO:0032268520.013
cellular component maintenanceGO:004395430.013
negative regulation of myeloid leukocyte differentiationGO:000276210.013
cytoskeleton dependent intracellular transportGO:0030705100.013
positive regulation of response to stimulusGO:0048584800.013
cell projection organizationGO:00300302840.013
cardiac atrium developmentGO:000323040.013
cellular response to chemical stimulusGO:00708871570.012
positive regulation of cellular catabolic processGO:003133130.012
regulation of cardiac muscle tissue developmentGO:005502410.012
protein localization to nucleusGO:003450430.012
digestive tract developmentGO:00485652650.012
response to radiationGO:0009314510.012
blood vessel developmentGO:00015682460.012
embryonic digestive tract morphogenesisGO:004855730.012
negative regulation of mitosisGO:004583930.012
immune responseGO:0006955280.012
protein localization to microtubule cytoskeletonGO:007269810.012
regulation of cell cycle processGO:0010564200.012
response to drugGO:004249330.012
proximal distal pattern formationGO:000995410.012
regulation of deoxyribonuclease activityGO:003207010.012
actin cytoskeleton organizationGO:0030036630.012
regulation of cell cycleGO:0051726520.012
determination of left right symmetryGO:00073681790.012
homeostasis of number of cells within a tissueGO:004887340.012
stem cell proliferationGO:007208940.012
embryo development ending in birth or egg hatchingGO:00097922710.012
negative regulation of apoptotic processGO:0043066550.012
cellular amino acid metabolic processGO:000652070.012
positive regulation of chromosome segregationGO:005198410.012
establishment of localizationGO:00512342440.011
negative regulation of cell growthGO:003030870.011
response to external biotic stimulusGO:0043207970.011
positive regulation of small gtpase mediated signal transductionGO:005105710.011
response to amineGO:001407510.011
regulation of dna metabolic processGO:0051052110.011
germ cell migrationGO:000835480.011
regulation of cellular amine metabolic processGO:003323800.011
response to nutrientGO:000758430.011
embryonic pattern specificationGO:0009880440.011
regulation of neural precursor cell proliferationGO:200017730.011
response to organic cyclic compoundGO:0014070510.011
regulation of intracellular signal transductionGO:1902531570.011
macromolecular complex subunit organizationGO:0043933740.011
regulation of signal transductionGO:00099662250.011
cellular response to dsrnaGO:007135910.011
vasculature developmentGO:00019442780.011
postsynaptic membrane organizationGO:000194130.011
response to chemicalGO:00422213200.011
regulation of response to stimulusGO:00485832690.011
positive regulation of signalingGO:0023056560.011
immunoglobulin productionGO:000237710.011
g2 dna damage checkpointGO:003157230.011
negative regulation of leukocyte differentiationGO:190210610.011
regulation of protein ubiquitinationGO:003139630.011
monovalent inorganic cation transportGO:0015672420.010
cell motilityGO:00488702440.010
positive regulation of nucleoside metabolic processGO:004597910.010
regulation of nervous system developmentGO:0051960900.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.010
cellular protein catabolic processGO:004425740.010
positive regulation of protein metabolic processGO:0051247230.010
cellular response to nutrient levelsGO:003166920.010
regulation of cellular component organizationGO:0051128860.010
response to endogenous stimulusGO:0009719830.010
regulation of transcription from rna polymerase ii promoterGO:00063571140.010
regulation of gene expressionGO:00104682650.010
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.010
cellular response to organic substanceGO:00713101050.010
cellular nitrogen compound catabolic processGO:0044270150.010
regulation of protein targetingGO:190353320.010
stem cell fate commitmentGO:004886510.010

brca2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
hematopoietic system diseaseDOID:7400.648
anemiaDOID:235500.648
disease of anatomical entityDOID:700.648
immune system diseaseDOID:291400.648
bone marrow diseaseDOID:496100.619
congenital hypoplastic anemiaDOID:134200.465
aplastic anemiaDOID:1244900.465
fanconi s anemiaDOID:1363600.465
inherited metabolic disorderDOID:65500.016
disease of metabolismDOID:001466700.016
musculoskeletal system diseaseDOID:1700.015
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011