Danio rerio

0 known processes

he1a

hatching enzyme 1a

(Aliases: cb284,wu:cegs2099,MGC111847,he1,zgc:111847)

he1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular biosynthetic processGO:00442492860.292
nucleic acid metabolic processGO:00903042440.155
positive regulation of cellular processGO:00485222010.144
Zebrafish
regulation of nucleobase containing compound metabolic processGO:00192192500.138
Zebrafish
aromatic compound biosynthetic processGO:00194382170.134
cellular nitrogen compound metabolic processGO:00346412900.133
nitrogen compound metabolic processGO:00068073190.118
regulation of biosynthetic processGO:00098892500.115
Zebrafish
regulation of cellular metabolic processGO:00313233200.110
Zebrafish
regulation of nucleic acid templated transcriptionGO:19035062130.109
Zebrafish
single organism localizationGO:19025782250.108
gene expressionGO:00104672520.103
embryonic organ developmentGO:00485683810.100
Zebrafish
macromolecule biosynthetic processGO:00090592270.100
regulation of cellular macromolecule biosynthetic processGO:20001122220.097
Zebrafish
cellular macromolecule biosynthetic processGO:00346452240.095
heterocycle biosynthetic processGO:00181302150.093
regulation of cellular biosynthetic processGO:00313262450.093
Zebrafish
gastrulationGO:00073692080.092
Zebrafish
lipid storageGO:001991510.091
cell surface receptor signaling pathwayGO:00071663250.089
Zebrafish
regulation of multicellular organismal processGO:00512392770.087
Zebrafish Worm
cell motilityGO:00488702440.087
regulation of developmental processGO:00507932470.086
Zebrafish Worm
larval developmentGO:000216420.083
nucleic acid templated transcriptionGO:00976591810.081
digestive system developmentGO:00551232890.080
Zebrafish Worm
regulation of nitrogen compound metabolic processGO:00511712510.079
Zebrafish
signal transductionGO:00071654550.078
Zebrafish
locomotionGO:00400113130.077
maintenance of locationGO:005123540.072
organic cyclic compound biosynthetic processGO:19013622230.072
rna metabolic processGO:00160702190.071
epithelial cell differentiationGO:00308551160.071
Zebrafish
regulation of macromolecule biosynthetic processGO:00105562250.071
Zebrafish
biosynthetic processGO:00090582940.067
cellular nitrogen compound biosynthetic processGO:00442712180.067
growthGO:00400071740.066
Worm
heterocycle metabolic processGO:00464832900.066
organic substance biosynthetic processGO:19015762890.064
cellular aromatic compound metabolic processGO:00067252950.062
sensory organ developmentGO:00074233930.061
cell projection organizationGO:00300302840.059
Worm
head developmentGO:00603223030.059
transportGO:00068102200.058
central nervous system developmentGO:00074173870.058
morphogenesis of an epitheliumGO:00020093330.058
muscle structure developmentGO:00610611960.057
inner ear receptor cell differentiationGO:0060113290.056
agingGO:000756820.056
regulation of rna metabolic processGO:00512522240.055
Zebrafish
organic cyclic compound metabolic processGO:19013603010.055
meiotic nuclear divisionGO:000712640.055
digestive tract morphogenesisGO:00485462310.054
Zebrafish
programmed cell deathGO:00125011190.054
regulation of rna biosynthetic processGO:20011412130.052
Zebrafish
regulation of metabolic processGO:00192223590.052
Zebrafish
lateral line system developmentGO:0048925760.051
heart contractionGO:0060047710.050
mitochondrion organizationGO:000700540.050
cellular protein catabolic processGO:004425740.048
nucleobase containing compound biosynthetic processGO:00346542050.048
transcription dna templatedGO:00063511810.047
single organism metabolic processGO:00447102170.046
proteasomal protein catabolic processGO:001049820.044
regulation of gene expressionGO:00104682650.044
Zebrafish
response to stressGO:00069502630.043
modification dependent protein catabolic processGO:001994130.043
specification of symmetryGO:00097992040.043
Zebrafish
regulation of multicellular organism growthGO:004001440.043
Worm
regulation of cell differentiationGO:00455951420.043
brain developmentGO:00074202930.043
positive regulation of purine nucleotide catabolic processGO:003312310.043
nucleobase containing compound metabolic processGO:00061392740.042
cellular macromolecule metabolic processGO:00442603910.042
positive regulation of cellular catabolic processGO:003133130.041
adult behaviorGO:003053420.040
proteolysis involved in cellular protein catabolic processGO:005160330.040
muscle cell differentiationGO:00426921390.039
positive regulation of nitrogen compound metabolic processGO:0051173690.039
positive regulation of nucleobase containing compound metabolic processGO:0045935690.039
ion transportGO:00068111140.038
amine metabolic processGO:000930820.038
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.038
sensory system developmentGO:0048880760.038
embryonic organ morphogenesisGO:00485622740.038
heart processGO:0003015710.038
regulation of macromolecule metabolic processGO:00602553170.036
Zebrafish
organelle organizationGO:00069962270.036
cellular response to chemical stimulusGO:00708871570.035
cell migrationGO:00164772370.035
chordate embryonic developmentGO:00430092710.035
regulation of epithelial cell proliferationGO:005067830.035
regulation of organ growthGO:004662030.035
generation of neuronsGO:00486993850.034
Worm
stem cell differentiationGO:00488631170.034
regulation of primary metabolic processGO:00800903110.034
Zebrafish
epidermal cell differentiationGO:0009913360.034
digestive tract developmentGO:00485652650.033
Zebrafish Worm
tube morphogenesisGO:00352393490.033
Zebrafish
cell projection morphogenesisGO:00488582440.032
transcription from rna polymerase ii promoterGO:0006366800.032
positive regulation of cell cycleGO:004578730.032
epidermis developmentGO:0008544480.032
sensory organ morphogenesisGO:00905962000.032
localization of cellGO:00516742440.032
regionalizationGO:00030022740.032
Zebrafish
positive regulation of biological processGO:00485182530.031
Zebrafish Worm
circulatory system processGO:0003013870.031
negative regulation of cellular processGO:00485232830.031
positive regulation of catabolic processGO:000989640.031
eye morphogenesisGO:00485921440.030
establishment of localizationGO:00512342440.030
cellular component morphogenesisGO:00329893360.030
system processGO:00030081850.029
multi organism processGO:00517041340.029
organonitrogen compound metabolic processGO:1901564740.029
positive regulation of cellular component biogenesisGO:004408930.029
modification dependent macromolecule catabolic processGO:004363230.029
ubiquitin dependent protein catabolic processGO:000651130.029
mesenchyme developmentGO:00604851270.029
negative regulation of biological processGO:00485193040.028
fin developmentGO:0033333770.028
Zebrafish
nucleocytoplasmic transportGO:000691340.028
neuron differentiationGO:00301823530.028
Worm
negative regulation of epithelial cell proliferationGO:005068010.028
nuclear transportGO:005116940.028
positive regulation of transportGO:005105020.028
positive regulation of nucleoside metabolic processGO:004597910.028
positive regulation of metabolic processGO:00098931080.028
organelle assemblyGO:00709251100.028
gtp metabolic processGO:004603940.027
cell morphogenesisGO:00009022890.027
rna biosynthetic processGO:00327741810.027
regulation of anatomical structure morphogenesisGO:00226031300.027
Zebrafish
regulation of biological qualityGO:00650082630.026
regulation of nucleotide catabolic processGO:003081120.026
response to abiotic stimulusGO:00096281220.026
posterior lateral line neuromast developmentGO:0048919200.026
regulation of protein modification by small protein conjugation or removalGO:190332030.026
multicellular organism growthGO:003526440.026
Worm
vasculature developmentGO:00019442780.026
Zebrafish
cell deathGO:00082191210.026
actin cytoskeleton organizationGO:0030036630.026
cell morphogenesis involved in differentiationGO:00009041950.026
meiotic chromosome segregationGO:004513230.025
response to chemicalGO:00422213200.025
hematopoietic or lymphoid organ developmentGO:00485341910.025
Zebrafish
skin developmentGO:0043588540.024
embryonic skeletal system developmentGO:0048706970.024
stem cell maintenanceGO:001982740.024
guanosine containing compound metabolic processGO:190106840.024
regulation of purine nucleotide catabolic processGO:003312120.024
blood vessel morphogenesisGO:00485142160.024
Zebrafish
cell part morphogenesisGO:00329902460.024
positive regulation of gene expressionGO:0010628710.024
hemopoiesisGO:00300971830.023
Zebrafish
epibolyGO:0090504410.023
cellular component assembly involved in morphogenesisGO:00109271070.023
regulation of cytokine productionGO:000181730.023
regulation of cellular component organizationGO:0051128860.023
positive regulation of cellular metabolic processGO:0031325940.023
cellular response to biotic stimulusGO:007121630.022
protein localization to nucleusGO:003450430.022
cellular component biogenesisGO:00440851780.022
regulation of cytoplasmic transportGO:190364940.022
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.022
Zebrafish
regulation of gtpase activityGO:004308720.022
single organism transportGO:00447652060.022
positive regulation of rna biosynthetic processGO:1902680570.022
cellular response to molecule of bacterial originGO:007121930.022
deathGO:00162651210.022
developmental growthGO:00485891660.022
Worm
neuromast developmentGO:0048884460.022
lateral line developmentGO:0048882660.022
positive regulation of biosynthetic processGO:0009891680.022
regulation of nucleoside metabolic processGO:000911820.022
b cell activationGO:004211320.021
single organism organelle organizationGO:19025891990.021
positive regulation of cellular biosynthetic processGO:0031328680.021
cilium morphogenesisGO:0060271850.021
striated muscle cell differentiationGO:00511461290.021
cellular response to lipopolysaccharideGO:007122230.021
positive regulation of rna metabolic processGO:0051254590.021
mechanoreceptor differentiationGO:0042490370.021
positive regulation of transcription dna templatedGO:0045893570.021
glial cell migrationGO:000834730.021
positive regulation of gtpase activityGO:004354710.021
cellular response to external stimulusGO:007149620.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.021
Zebrafish
negative regulation of protein phosphorylationGO:000193340.020
small molecule metabolic processGO:0044281770.020
cellular protein metabolic processGO:00442671290.020
regulation of protein ubiquitinationGO:003139630.020
meiotic cell cycle processGO:190304630.020
cytoskeleton organizationGO:0007010960.020
glucose homeostasisGO:004259310.020
autophagyGO:000691440.020
posterior lateral line system developmentGO:0048915460.019
regulation of circadian rhythmGO:004275240.019
lamellipodium assemblyGO:003003210.019
inner ear developmentGO:00488391260.019
ear developmentGO:00435831270.019
immune system developmentGO:00025201910.019
Zebrafish
protein stabilizationGO:005082120.019
ectodermal placode developmentGO:0071696370.019
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
Zebrafish
regulation of synapse organizationGO:005080730.019
cellular amide metabolic processGO:004360340.019
anterior posterior pattern specificationGO:00099521520.019
positive regulation of nucleic acid templated transcriptionGO:1903508570.019
regenerationGO:0031099910.019
negative regulation of biosynthetic processGO:0009890550.019
synaptic target recognitionGO:000803910.019
striated muscle tissue developmentGO:00147061100.018
regulation of synapse assemblyGO:005196330.018
tissue remodelingGO:004877140.018
protein import into nucleusGO:000660630.018
carboxylic acid metabolic processGO:0019752220.018
regulation of cell developmentGO:00602841000.018
regulation of signalingGO:00230512350.018
Zebrafish
positive regulation of macromolecule biosynthetic processGO:0010557590.018
guanosine containing compound catabolic processGO:190106920.018
determination of bilateral symmetryGO:00098552040.018
Zebrafish
regulation of reproductive processGO:200024140.018
positive regulation of response to stimulusGO:0048584800.018
Zebrafish
angiogenesisGO:00015251580.018
Zebrafish
protein importGO:001703830.018
response to woundingGO:00096111160.018
apoptotic processGO:00069151160.018
cellular component movementGO:00069283350.017
regulation of gtp catabolic processGO:003312420.017
intracellular signal transductionGO:0035556850.017
phagocytosisGO:000690930.017
sensory perception of chemical stimulusGO:000760630.017
eye developmentGO:00016542770.017
blood circulationGO:0008015870.017
macromolecule modificationGO:00434121110.017
homeostasis of number of cellsGO:0048872620.017
response to external stimulusGO:00096052640.017
negative regulation of cellular biosynthetic processGO:0031327550.017
entrainment of circadian clockGO:000964920.017
regulation of response to stimulusGO:00485832690.017
Zebrafish
protein targeting to nucleusGO:004474430.017
organic acid metabolic processGO:0006082310.017
regulation of transcription dna templatedGO:00063552130.017
Zebrafish
appendage morphogenesisGO:0035107560.017
Zebrafish
cellular amine metabolic processGO:004410620.016
oxoacid metabolic processGO:0043436310.016
embryonic skeletal system morphogenesisGO:0048704930.016
negative regulation of multicellular organismal processGO:0051241690.016
phenol containing compound biosynthetic processGO:004618940.016
regulation of multicellular organismal developmentGO:20000262230.016
Zebrafish
regulation of signal transductionGO:00099662250.016
Zebrafish
response to organic substanceGO:00100331530.016
positive regulation of cell adhesionGO:004578510.016
nuclear importGO:005117030.016
lateral inhibitionGO:004633110.016
mechanosensory lateral line system developmentGO:0048881490.016
macromolecule localizationGO:0033036540.016
stem cell proliferationGO:007208940.016
skeletal muscle tissue developmentGO:0007519670.016
positive regulation of gtp catabolic processGO:003312610.016
gtp catabolic processGO:000618420.015
cell matrix adhesionGO:000716040.015
cognitionGO:005089010.015
response to monosaccharideGO:003428430.015
morphogenesis of an epithelial sheetGO:0002011490.015
striated muscle cell developmentGO:00550021080.015
positive regulation of translationGO:004572710.015
ras protein signal transductionGO:000726570.015
female meiotic divisionGO:000714320.015
response to glucoseGO:000974930.015
ameboidal type cell migrationGO:00016671430.015
synaptic growth at neuromuscular junctionGO:005112420.015
muscle organ developmentGO:00075171010.015
carbohydrate homeostasisGO:003350010.015
muscle tissue developmentGO:00605371100.015
hair cell differentiationGO:0035315320.015
regulation of protein transportGO:005122330.015
cell proliferationGO:0008283800.015
mesoderm developmentGO:0007498880.015
Zebrafish
regulation of protein catabolic processGO:004217610.015
regulation of reactive oxygen species metabolic processGO:200037720.015
skeletal muscle organ developmentGO:0060538780.015
primary neural tube formationGO:001402010.015
response to endogenous stimulusGO:0009719830.014
behaviorGO:0007610740.014
Worm
response to hexoseGO:000974630.014
regulation of autophagyGO:001050630.014
regulation of cell communicationGO:00106462320.014
Zebrafish
cellular amino acid metabolic processGO:000652070.014
locomotor rhythmGO:004547530.014
embryonic hemopoiesisGO:0035162530.014
Zebrafish
neuromuscular process controlling balanceGO:005088530.014
cellular response to stressGO:0033554620.014
erythrocyte homeostasisGO:0034101550.014
regulation of apoptotic processGO:0042981980.014
regulation of cell activationGO:005086510.014
heart developmentGO:00075073130.014
gland developmentGO:00487321430.014
membrane repolarizationGO:008600920.014
homeostatic processGO:00425921420.014
cellular response to starvationGO:000926710.014
macroautophagyGO:001623610.014
olfactory bulb developmentGO:002177240.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
Zebrafish
kidney developmentGO:0001822920.014
cardiocyte differentiationGO:0035051440.013
epithelial cell morphogenesisGO:000338220.013
cellular response to organic substanceGO:00713101050.013
embryonic viscerocranium morphogenesisGO:0048703520.013
regulation of cell deathGO:00109411030.013
negative regulation of rna metabolic processGO:0051253480.013
protein metabolic processGO:00195381830.013
Zebrafish
embryonic cranial skeleton morphogenesisGO:0048701900.013
cell cycleGO:0007049930.013
immune system processGO:00023762410.013
Zebrafish
cellular localizationGO:0051641970.013
establishment of rna localizationGO:005123630.013
extrinsic apoptotic signaling pathwayGO:009719130.013
epiboly involved in gastrulation with mouth forming secondGO:0055113350.013
hindbrain developmentGO:0030902910.013
embryo development ending in birth or egg hatchingGO:00097922710.013
Worm
antimicrobial humoral responseGO:001973020.013
fin morphogenesisGO:0033334530.013
Zebrafish
cellular component assemblyGO:00226071700.013
positive regulation of macromolecule metabolic processGO:0010604930.013
mesenchymal cell differentiationGO:0048762870.013
cellular response to nutrient levelsGO:003166920.013
epithelial tube formationGO:0072175190.013
regulation of blood pressureGO:000821710.013
nucleic acid transportGO:005065720.013
mitochondrial transportGO:000683920.012
negative regulation of cellular metabolic processGO:0031324770.012
spindle assemblyGO:005122520.012
nuclear exportGO:005116810.012
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.012
compound eye developmentGO:004874920.012
regulation of cellular amine metabolic processGO:003323800.012
regulation of metal ion transportGO:001095940.012
connective tissue developmentGO:0061448990.012
cartilage developmentGO:0051216960.012
response to nutrientGO:000758430.012
negative regulation of reproductive processGO:200024230.012
camera type eye developmentGO:00430102220.012
cellular response to estrogen stimulusGO:0071391240.012
establishment of protein localization to organelleGO:007259440.012
activation of mapk activityGO:000018730.012
photoreceptor cell fate commitmentGO:004655210.012
regulation of epidermis developmentGO:004568220.012
negative regulation of nucleobase containing compound metabolic processGO:0045934590.012
regulation of cell shapeGO:000836010.012
forebrain cell migrationGO:002188510.012
negative regulation of macromolecule biosynthetic processGO:0010558480.012
cell substrate junction assemblyGO:000704420.012
rna localizationGO:000640340.012
endothelium developmentGO:0003158250.012
Zebrafish
neuron projection morphogenesisGO:00488121610.012
embryonic heart tube developmentGO:00350501330.012
positive regulation of nucleotide catabolic processGO:003081310.011
hatchingGO:003518840.011
Zebrafish
negative regulation of nitrogen compound metabolic processGO:0051172590.011
response to external biotic stimulusGO:0043207970.011
detection of chemical stimulusGO:000959340.011
regulation of neuron differentiationGO:0045664560.011
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.011
spermatid developmentGO:000728620.011
regulation of cellular ketone metabolic processGO:001056570.011
posterior lateral line developmentGO:0048916380.011
lamellipodium organizationGO:009758110.011
tube closureGO:006060610.011
regulation of stem cell differentiationGO:200073640.011
actomyosin structure organizationGO:0031032530.011
response to carbohydrateGO:000974330.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
translational initiationGO:000641330.011
regulation of neurogenesisGO:0050767870.011
regulation of cell morphogenesisGO:0022604420.011
cell fate commitmentGO:0045165990.011
myeloid cell homeostasisGO:0002262560.011
chemosensory behaviorGO:000763510.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
peptide metabolic processGO:000651810.011
lymphocyte proliferationGO:004665110.011
cellular ketone metabolic processGO:0042180110.011
single organism nuclear importGO:190259330.011
rhombomere 5 developmentGO:002157140.011
protein polymerizationGO:005125840.011
hormone transportGO:000991420.011
morphogenesis of embryonic epitheliumGO:0016331300.010
regulation of cellular amino acid metabolic processGO:000652100.010
axon developmentGO:00615641660.010
Worm
ribonucleoside monophosphate catabolic processGO:000915840.010
positive regulation of cell substrate adhesionGO:001081110.010
secondary metabolic processGO:001974830.010
hormone secretionGO:004687920.010
positive regulation of multicellular organismal processGO:0051240520.010
Zebrafish Worm
negative regulation of protein kinase activityGO:000646940.010
cellular protein modification processGO:00064641000.010
gastrulation with mouth forming secondGO:0001702440.010
catecholamine metabolic processGO:000658420.010
nucleobase containing small molecule metabolic processGO:0055086320.010
alpha amino acid metabolic processGO:190160530.010
positive regulation of stress activated mapk cascadeGO:003287430.010
protein localization to plasma membraneGO:007265910.010
cation transportGO:0006812810.010
exocytosisGO:000688710.010
positive regulation of cell communicationGO:0010647560.010
Zebrafish
regulation of retina development in camera type eyeGO:190286620.010
wound healingGO:0042060900.010
positive regulation of secretionGO:005104710.010
actin filament based processGO:0030029640.010
negative regulation of multi organism processGO:004390130.010
positive regulation of signal transductionGO:0009967560.010
Zebrafish
regulation of organelle assemblyGO:190211540.010
chemical homeostasisGO:0048878490.010
intestinal cholesterol absorptionGO:003029920.010

he1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
nervous system diseaseDOID:86300.017
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
disease of metabolismDOID:001466700.011
organ system cancerDOID:005068600.010
sensory system diseaseDOID:005015500.010