Danio rerio

0 known processes

hint2

histidine triad nucleotide binding protein 2

(Aliases: MGC163082,si:dkey-87i10.2,zgc:163082)

hint2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
inner ear developmentGO:00488391260.287
transmembrane transportGO:00550851200.235
ear developmentGO:00435831270.218
sensory organ developmentGO:00074233930.166
response to external stimulusGO:00096052640.164
semicircular canal developmentGO:0060872240.125
cytosolic calcium ion transportGO:006040130.083
regulation of cell projection assemblyGO:006049140.079
larval developmentGO:000216420.076
organelle organizationGO:00069962270.074
vasculature developmentGO:00019442780.072
mitochondrion organizationGO:000700540.071
positive regulation of transportGO:005105020.068
positive regulation of secretionGO:005104710.067
actin polymerization or depolymerizationGO:000815420.064
regulation of reactive oxygen species metabolic processGO:200037720.064
positive regulation of biological processGO:00485182530.063
regulation of synaptic plasticityGO:004816710.061
agingGO:000756820.058
angiogenesisGO:00015251580.056
regulation of guanylate cyclase activityGO:003128260.055
central nervous system developmentGO:00074173870.055
regulation of protein modification by small protein conjugation or removalGO:190332030.055
cellular response to toxic substanceGO:009723710.052
hydrogen peroxide metabolic processGO:004274320.050
positive regulation of protein polymerizationGO:003227320.050
cell projection organizationGO:00300302840.049
maintenance of locationGO:005123540.048
biosynthetic processGO:00090582940.047
multicellular organism growthGO:003526440.047
amine metabolic processGO:000930820.047
positive regulation of cgmp biosynthetic processGO:003082860.046
establishment of localizationGO:00512342440.046
regulation of protein ubiquitinationGO:003139630.043
somite developmentGO:0061053960.043
cellular transition metal ion homeostasisGO:004691630.043
regulation of multicellular organism growthGO:004001440.043
taste bud formationGO:006119530.042
single organism transportGO:00447652060.041
g protein coupled receptor signaling pathwayGO:0007186740.041
cognitionGO:005089010.040
sensory organ morphogenesisGO:00905962000.039
regulation of reproductive processGO:200024140.039
single organism localizationGO:19025782250.039
skeletal muscle organ developmentGO:0060538780.039
embryonic organ developmentGO:00485683810.039
phototransduction visible lightGO:000760320.039
negative regulation of kinase activityGO:003367340.039
negative regulation of biological processGO:00485193040.038
head developmentGO:00603223030.038
regulation of cellular amino acid metabolic processGO:000652100.037
positive regulation of muscle tissue developmentGO:190186310.037
developmental programmed cell deathGO:001062340.036
regulation of response to oxidative stressGO:190288220.036
regulation of cgmp biosynthetic processGO:003082660.035
cellular amino acid metabolic processGO:000652070.035
oocyte maturationGO:000155640.034
regulation of cellular amine metabolic processGO:003323800.034
cellular response to light stimulusGO:007148240.034
heart morphogenesisGO:00030071560.033
positive regulation of striated muscle tissue developmentGO:004584410.032
heart developmentGO:00075073130.032
positive regulation of blood circulationGO:190352420.032
organic acid metabolic processGO:0006082310.032
cellular ketone metabolic processGO:0042180110.032
embryonic heart tube morphogenesisGO:00031431080.032
rhodopsin mediated signaling pathwayGO:001605610.032
positive regulation of muscle organ developmentGO:004863610.032
tube morphogenesisGO:00352393490.031
cellular component movementGO:00069283350.031
single organism metabolic processGO:00447102170.030
regulation of protein complex assemblyGO:004325430.030
cellular macromolecule metabolic processGO:00442603910.030
actin filament polymerizationGO:003004120.030
intramembranous ossificationGO:000195730.030
cellular localizationGO:0051641970.030
carboxylic acid metabolic processGO:0019752220.030
positive regulation of cellular amine metabolic processGO:003324000.030
locomotionGO:00400113130.029
embryonic organ morphogenesisGO:00485622740.029
regulation of muscle contractionGO:000693730.029
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.029
cellular response to chemical stimulusGO:00708871570.029
phototransductionGO:000760220.029
monoamine transportGO:001584410.029
signal transductionGO:00071654550.028
system processGO:00030081850.028
regulation of metal ion transportGO:001095940.027
chordate embryonic developmentGO:00430092710.027
protein polymerizationGO:005125840.027
cellular protein catabolic processGO:004425740.027
striated muscle cell differentiationGO:00511461290.027
cellular response to decreased oxygen levelsGO:003629410.027
cellular component biogenesisGO:00440851780.027
transportGO:00068102200.027
cellular response to radiationGO:007147840.027
blood vessel morphogenesisGO:00485142160.026
cellular component morphogenesisGO:00329893360.026
single organism organelle organizationGO:19025891990.026
blood vessel developmentGO:00015682460.026
regulation of protein polymerizationGO:003227120.026
adult behaviorGO:003053420.026
determination of bilateral symmetryGO:00098552040.025
positive regulation of cellular amino acid metabolic processGO:004576400.025
locus ceruleus developmentGO:002170330.025
erk1 and erk2 cascadeGO:007037140.025
organic substance biosynthetic processGO:19015762890.025
heart processGO:0003015710.025
negative regulation of protein phosphorylationGO:000193340.025
positive regulation of cellular component biogenesisGO:004408930.024
regulation of filopodium assemblyGO:005148920.024
long chain fatty acid transportGO:001590910.024
ion transportGO:00068111140.024
positive regulation of cytosolic calcium ion concentrationGO:000720440.024
positive regulation of cellular processGO:00485222010.024
direct ossificationGO:003607230.024
regulation of sodium ion transportGO:000202820.023
cell death in response to oxidative stressGO:003647320.023
regulation of peptidyl tyrosine phosphorylationGO:005073010.023
regulation of blood pressureGO:000821710.023
regulation of localizationGO:00328791040.022
sequestering of metal ionGO:005123830.022
regulation of cellular response to oxidative stressGO:190040720.022
cgmp metabolic processGO:004606870.022
ribonucleoside monophosphate catabolic processGO:000915840.022
heart contractionGO:0060047710.022
hindbrain formationGO:002157630.022
cation transmembrane transportGO:0098655650.022
autophagyGO:000691440.022
nucleobase containing compound biosynthetic processGO:00346542050.022
small molecule metabolic processGO:0044281770.021
macromolecular complex subunit organizationGO:0043933740.021
regulation of blood vessel sizeGO:005088020.021
brain developmentGO:00074202930.021
response to drugGO:004249330.021
positive regulation of secretion by cellGO:190353210.021
establishment of localization in cellGO:0051649770.021
limb bud formationGO:006017420.021
calcium ion transmembrane transportGO:0070588130.021
inner ear morphogenesisGO:0042472630.021
circulatory system processGO:0003013870.021
organonitrogen compound metabolic processGO:1901564740.021
regulation of receptor mediated endocytosisGO:004825940.020
regulation of signalingGO:00230512350.020
cellular response to external stimulusGO:007149620.020
regulation of gene expressionGO:00104682650.020
establishment of synaptic vesicle localizationGO:009748010.020
protein complex biogenesisGO:0070271300.020
intracellular signal transductionGO:0035556850.019
specification of symmetryGO:00097992040.019
determination of left right symmetryGO:00073681790.019
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.019
neurotransmitter transportGO:000683620.019
regulation of cellular ketone metabolic processGO:001056570.019
cell morphogenesis involved in differentiationGO:00009041950.019
negative regulation of developmental processGO:0051093650.019
cellular respirationGO:004533330.019
neuron neuron synaptic transmissionGO:000727010.018
heart loopingGO:0001947940.018
regulation of transporter activityGO:003240920.018
regulation of ion transmembrane transporter activityGO:003241220.018
positive regulation of protein complex assemblyGO:003133420.018
oxidation reduction processGO:0055114410.018
regulation of cellular metabolic processGO:00313233200.018
smooth muscle contractionGO:000693920.018
porphyrin containing compound metabolic processGO:0006778100.017
actin filament based movementGO:003004810.017
stem cell maintenanceGO:001982740.017
cardiac muscle cell differentiationGO:0055007300.017
regulation of hydrogen peroxide metabolic processGO:001031010.017
negative regulation of cellular processGO:00485232830.017
regulation of oxidative stress induced cell deathGO:190320120.017
cellular component disassemblyGO:002241110.017
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.017
protein heterooligomerizationGO:005129110.017
regulation of neurotransmitter secretionGO:004692810.016
rhombomere 6 developmentGO:002157240.016
synaptic vesicle transportGO:004848910.016
response to vitaminGO:003327330.016
regulation of skeletal muscle tissue developmentGO:004864140.016
regulation of calcium ion transportGO:005192420.016
cell morphogenesisGO:00009022890.016
regulation of receptor internalizationGO:000209020.016
anterior posterior pattern specificationGO:00099521520.016
skeletal muscle tissue developmentGO:0007519670.016
negative regulation of map kinase activityGO:004340720.016
regulation of fatty acid metabolic processGO:001921710.016
organelle fusionGO:004828430.016
negative regulation of mapk cascadeGO:004340940.016
negative regulation of epithelial cell proliferationGO:005068010.016
lipid homeostasisGO:005508830.016
generation of neuronsGO:00486993850.016
purine ribonucleoside monophosphate catabolic processGO:000916940.016
determination of heart left right asymmetryGO:00613711170.016
embryo development ending in birth or egg hatchingGO:00097922710.016
semicircular canal formationGO:006087640.016
microtubule depolymerizationGO:000701910.016
peptidyl serine phosphorylationGO:001810510.015
inorganic cation transmembrane transportGO:0098662500.015
tissue remodelingGO:004877140.015
regulation of biological qualityGO:00650082630.015
specification of axis polarityGO:006500140.015
regulation of multicellular organismal processGO:00512392770.015
response to carbohydrateGO:000974330.015
regulation of endothelial cell proliferationGO:000193610.015
sensory perceptionGO:0007600390.015
regulation of cell communicationGO:00106462320.015
muscle contractionGO:0006936180.015
nitrogen compound metabolic processGO:00068073190.015
response to monosaccharideGO:003428430.015
regulation of bindingGO:005109830.015
regulation of transmembrane transporter activityGO:002289820.015
meiotic chromosome segregationGO:004513230.015
positive regulation of skeletal muscle tissue developmentGO:004864310.015
astrocyte differentiationGO:004870810.015
positive regulation of exocytosisGO:004592110.015
neurotransmitter secretionGO:000726920.015
small molecule catabolic processGO:004428230.015
kupffer s vesicle developmentGO:0070121500.014
regulation of release of sequestered calcium ion into cytosolGO:005127910.014
spermatid developmentGO:000728620.014
regulation of tube sizeGO:003515020.014
macromolecule biosynthetic processGO:00090592270.014
cellular component assemblyGO:00226071700.014
protein importGO:001703830.014
organic cyclic compound metabolic processGO:19013603010.014
olfactory lobe developmentGO:002198840.014
renal system processGO:0003014140.014
meiotic cell cycle processGO:190304630.014
establishment of protein localization to organelleGO:007259440.014
protein metabolic processGO:00195381830.014
regulation of metabolic processGO:00192223590.014
mitotic dna integrity checkpointGO:004477440.014
positive regulation of cell cycleGO:004578730.014
regulation of macromolecule metabolic processGO:00602553170.014
cellular response to nutrient levelsGO:003166920.014
regulation of meiotic cell cycleGO:005144510.014
growthGO:00400071740.014
spermatid differentiationGO:004851520.014
receptor internalizationGO:003162320.014
multi organism processGO:00517041340.014
regulation of nucleotide biosynthetic processGO:0030808150.013
response to foodGO:003209410.013
regulation of bone remodelingGO:004685020.013
homeostasis of number of cells within a tissueGO:004887340.013
cellular amine metabolic processGO:004410620.013
meiotic nuclear divisionGO:000712640.013
compound eye developmentGO:004874920.013
regulation of neurotransmitter transportGO:005158810.013
regulation of developmental processGO:00507932470.013
reactive oxygen species metabolic processGO:007259360.013
regulation of organelle assemblyGO:190211540.013
mitochondrial transportGO:000683920.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
response to nutrientGO:000758430.013
reproductionGO:0000003400.013
positive regulation of heart contractionGO:004582320.013
regulation of intracellular protein transportGO:003315730.013
cell projection morphogenesisGO:00488582440.013
membrane hyperpolarizationGO:006008110.013
light induced release of internally sequestered calcium ionGO:000837710.013
response to abiotic stimulusGO:00096281220.013
insulin like growth factor receptor signaling pathwayGO:004800940.013
negative regulation of intracellular transportGO:003238730.013
response to hexoseGO:000974630.013
response to antibioticGO:004667710.013
modification dependent protein catabolic processGO:001994130.013
regulation of protein transportGO:005122330.013
regulation of insulin like growth factor receptor signaling pathwayGO:004356710.013
heterocycle metabolic processGO:00464832900.013
regulation of cyclase activityGO:0031279120.012
response to glucoseGO:000974930.012
ventricular cardiac muscle tissue morphogenesisGO:005501020.012
tetrapyrrole metabolic processGO:0033013100.012
ion transmembrane transportGO:0034220910.012
inner ear receptor cell differentiationGO:0060113290.012
cellular biosynthetic processGO:00442492860.012
synaptic vesicle localizationGO:009747910.012
macromolecule modificationGO:00434121110.012
ear morphogenesisGO:0042471640.012
negative regulation of blood circulationGO:190352320.012
photoreceptor cell fate specificationGO:004370410.012
organonitrogen compound biosynthetic processGO:1901566470.012
response to stressGO:00069502630.012
cellular nitrogen compound metabolic processGO:00346412900.012
cell agingGO:000756920.012
negative regulation of protein kinase activityGO:000646940.012
neurological system processGO:0050877620.012
cgmp biosynthetic processGO:000618270.012
regulation of cytoplasmic transportGO:190364940.012
embryonic skeletal joint developmentGO:007249830.012
organic cyclic compound biosynthetic processGO:19013622230.012
developmental growthGO:00485891660.012
positive regulation of cellular catabolic processGO:003133130.012
embryonic limb morphogenesisGO:003032620.012
mesenchyme developmentGO:00604851270.012
striated muscle cell developmentGO:00550021080.012
lipid catabolic processGO:001604240.012
negative regulation of catabolic processGO:000989530.012
organelle localizationGO:0051640490.012
cell projection assemblyGO:0030031640.011
neuron differentiationGO:00301823530.011
synaptic transmission cholinergicGO:000727140.011
chemosensory behaviorGO:000763510.011
cell proliferationGO:0008283800.011
deathGO:00162651210.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
neuron projection developmentGO:00311751800.011
muscle structure developmentGO:00610611960.011
protein stabilizationGO:005082120.011
carbon dioxide transportGO:001567030.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
sequestering of calcium ionGO:005120830.011
inositol lipid mediated signalingGO:004801720.011
localization of cellGO:00516742440.011
i kappab kinase nf kappab signalingGO:000724940.011
striated muscle tissue developmentGO:00147061100.011
protein complex disassemblyGO:004324110.011
single organism membrane fusionGO:004480120.011
chromosome organization involved in meiosisGO:007019210.011
positive regulation of cytoskeleton organizationGO:005149530.011
cellular response to vascular endothelial growth factor stimulusGO:003592430.011
regulation of lyase activityGO:0051339120.011
negative regulation of cellular catabolic processGO:003133030.011
cyclic nucleotide biosynthetic processGO:0009190180.011
respiratory electron transport chainGO:002290420.011
cellular aldehyde metabolic processGO:000608140.011
gtp catabolic processGO:000618420.011
regulation of systemic arterial blood pressureGO:000307310.011
nuclear transportGO:005116940.011
ventricular cardiac muscle tissue developmentGO:000322930.011
cell part morphogenesisGO:00329902460.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
actin filament based processGO:0030029640.010
regulation of gastrulationGO:0010470240.010
negative regulation of dna metabolic processGO:005105340.010
regulation of mitochondrion organizationGO:001082110.010
regulation of blood circulationGO:1903522320.010
regulation of carbohydrate biosynthetic processGO:004325510.010
single organism nuclear importGO:190259330.010
locomotor rhythmGO:004547530.010
sensory perception of chemical stimulusGO:000760630.010
fat soluble vitamin metabolic processGO:000677540.010
release of sequestered calcium ion into cytosolGO:005120930.010
muscle cell differentiationGO:00426921390.010
morphogenesis of an epitheliumGO:00020093330.010
blood circulationGO:0008015870.010
detection of external stimulusGO:0009581240.010
negative regulation of signalingGO:0023057960.010
regulation of epithelial cell proliferationGO:005067830.010
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
cell cell signalingGO:0007267520.010
cellular response to hypoxiaGO:007145610.010
sleepGO:003043110.010
regulation of i kappab kinase nf kappab signalingGO:004312240.010
regulation of tissue remodelingGO:003410320.010
development of primary female sexual characteristicsGO:004654540.010

hint2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.094
neurodegenerative diseaseDOID:128900.094
parkinson s diseaseDOID:1433000.094
disease of anatomical entityDOID:700.094
central nervous system diseaseDOID:33100.094
synucleinopathyDOID:005089000.094
disease of metabolismDOID:001466700.051
inherited metabolic disorderDOID:65500.051
muscle tissue diseaseDOID:6600.013
muscular diseaseDOID:008000000.013
myopathyDOID:42300.013
musculoskeletal system diseaseDOID:1700.013