Danio rerio

0 known processes

spo11

SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)

(Aliases: MGC77876,zgc:77876)

spo11 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.099
agingGO:000756820.085
nitrogen compound metabolic processGO:00068073190.061
cellular nitrogen compound metabolic processGO:00346412900.044
cellular macromolecule metabolic processGO:00442603910.043
phagocytosisGO:000690930.043
meiotic nuclear divisionGO:000712640.040
regulation of metabolic processGO:00192223590.040
gene expressionGO:00104672520.040
biosynthetic processGO:00090582940.038
positive regulation of cell cycleGO:004578730.038
response to chemicalGO:00422213200.037
heterocycle metabolic processGO:00464832900.037
signal transductionGO:00071654550.037
cellular biosynthetic processGO:00442492860.036
organic substance biosynthetic processGO:19015762890.036
regulation of primary metabolic processGO:00800903110.035
maintenance of locationGO:005123540.034
regulation of cellular metabolic processGO:00313233200.034
cytokinesisGO:000091030.034
negative regulation of protein phosphorylationGO:000193340.033
regulation of cellular amine metabolic processGO:003323800.033
organic cyclic compound metabolic processGO:19013603010.033
regulation of multicellular organism growthGO:004001440.032
cellular macromolecule biosynthetic processGO:00346452240.032
positive regulation of transportGO:005105020.032
cellular component morphogenesisGO:00329893360.032
amine metabolic processGO:000930820.031
cellular amine metabolic processGO:004410620.031
cellular aromatic compound metabolic processGO:00067252950.031
multicellular organism growthGO:003526440.030
regulation of cellular macromolecule biosynthetic processGO:20001122220.030
rna metabolic processGO:00160702190.030
regulation of nitrogen compound metabolic processGO:00511712510.030
nucleic acid templated transcriptionGO:00976591810.030
ubiquitin dependent protein catabolic processGO:000651130.030
regulation of macromolecule metabolic processGO:00602553170.029
modification dependent protein catabolic processGO:001994130.029
nucleic acid metabolic processGO:00903042440.029
regulation of cellular biosynthetic processGO:00313262450.029
regulation of rna metabolic processGO:00512522240.028
regulation of biosynthetic processGO:00098892500.028
cell morphogenesisGO:00009022890.028
establishment of protein localization to organelleGO:007259440.028
regulation of gene expressionGO:00104682650.028
proteolysis involved in cellular protein catabolic processGO:005160330.028
cellular ketone metabolic processGO:0042180110.028
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.027
macromolecule biosynthetic processGO:00090592270.027
regulation of establishment of protein localizationGO:007020140.027
cognitionGO:005089010.027
nucleobase containing compound metabolic processGO:00061392740.027
single organism metabolic processGO:00447102170.026
oxoacid metabolic processGO:0043436310.026
modification dependent macromolecule catabolic processGO:004363230.026
nucleobase containing compound biosynthetic processGO:00346542050.026
regulation of cellular amino acid metabolic processGO:000652100.026
transcription dna templatedGO:00063511810.026
cell projection morphogenesisGO:00488582440.026
organelle organizationGO:00069962270.026
negative regulation of protein kinase activityGO:000646940.026
regulation of nucleobase containing compound metabolic processGO:00192192500.025
neuron differentiationGO:00301823530.025
cellular nitrogen compound biosynthetic processGO:00442712180.025
organic cyclic compound biosynthetic processGO:19013622230.025
heterocycle biosynthetic processGO:00181302150.025
regulation of meiotic cell cycleGO:005144510.025
immune system processGO:00023762410.025
establishment of localizationGO:00512342440.025
regulation of cell activationGO:005086510.025
locomotionGO:00400113130.025
stem cell maintenanceGO:001982740.024
tube morphogenesisGO:00352393490.024
cellular component movementGO:00069283350.024
negative regulation of kinase activityGO:003367340.024
heart developmentGO:00075073130.024
cell surface receptor signaling pathwayGO:00071663250.024
organonitrogen compound metabolic processGO:1901564740.024
transportGO:00068102200.024
small molecule metabolic processGO:0044281770.024
regulation of reproductive processGO:200024140.024
response to stressGO:00069502630.024
proteasomal protein catabolic processGO:001049820.024
protein localization to nucleusGO:003450430.024
rna biosynthetic processGO:00327741810.024
regulation of macromolecule biosynthetic processGO:00105562250.024
regulation of protein transportGO:005122330.023
cell migrationGO:00164772370.023
adult behaviorGO:003053420.023
nuclear transportGO:005116940.023
regulation of cellular ketone metabolic processGO:001056570.023
autophagyGO:000691440.023
negative regulation of cellular processGO:00485232830.023
internal protein amino acid acetylationGO:000647520.023
positive regulation of biological processGO:00485182530.022
cellular amino acid metabolic processGO:000652070.022
cellular protein catabolic processGO:004425740.022
generation of neuronsGO:00486993850.022
regulation of protein localization to nucleusGO:190018020.022
regulation of rna biosynthetic processGO:20011412130.022
muscle structure developmentGO:00610611960.022
single organism localizationGO:19025782250.022
golgi vesicle transportGO:004819330.022
protein importGO:001703830.021
positive regulation of catabolic processGO:000989640.021
response to drugGO:004249330.021
regulation of transcription dna templatedGO:00063552130.021
organic acid metabolic processGO:0006082310.021
negative regulation of biological processGO:00485193040.021
cell projection organizationGO:00300302840.021
carboxylic acid metabolic processGO:0019752220.021
lipid storageGO:001991510.021
nucleocytoplasmic transportGO:000691340.021
ribonucleoside monophosphate catabolic processGO:000915840.021
guanosine containing compound metabolic processGO:190106840.021
cytoskeleton dependent cytokinesisGO:006164030.020
gtp catabolic processGO:000618420.020
positive regulation of cellular component biogenesisGO:004408930.020
protein metabolic processGO:00195381830.020
vasculature developmentGO:00019442780.020
guanosine containing compound catabolic processGO:190106920.020
extrinsic apoptotic signaling pathwayGO:009719130.020
digestive system developmentGO:00551232890.020
fertilizationGO:000956630.020
neurotransmitter transportGO:000683620.019
regulation of biological qualityGO:00650082630.019
regulation of cytokine productionGO:000181730.019
regulation of response to stimulusGO:00485832690.019
aromatic compound biosynthetic processGO:00194382170.019
sensory organ developmentGO:00074233930.019
embryonic organ developmentGO:00485683810.019
nuclear importGO:005117030.019
atp catabolic processGO:000620040.019
regulation of nucleocytoplasmic transportGO:004682220.019
cell part morphogenesisGO:00329902460.019
regulation of multicellular organismal developmentGO:20000262230.019
cellular amide metabolic processGO:004360340.019
positive regulation of cellular amine metabolic processGO:003324000.019
regulation of cytoplasmic transportGO:190364940.019
protein acetylationGO:000647320.018
response to carbohydrateGO:000974330.018
protein heterooligomerizationGO:005129110.018
neuron developmentGO:00486662620.018
regulation of intracellular protein transportGO:003315730.018
transcription from rna polymerase ii promoterGO:0006366800.018
regulation of developmental processGO:00507932470.018
morphogenesis of an epitheliumGO:00020093330.018
cellular carbohydrate metabolic processGO:004426240.018
purine ribonucleoside monophosphate catabolic processGO:000916940.018
synaptic growth at neuromuscular junctionGO:005112420.018
neurotransmitter secretionGO:000726920.018
regulation of metal ion transportGO:001095940.018
female sex differentiationGO:004666040.018
single organism transportGO:00447652060.018
lipid catabolic processGO:001604240.018
embryo development ending in birth or egg hatchingGO:00097922710.018
positive regulation of cellular processGO:00485222010.018
system processGO:00030081850.018
regulation of bindingGO:005109830.018
cell motilityGO:00488702440.018
mononuclear cell proliferationGO:003294310.018
regulation of synaptic plasticityGO:004816710.018
leukocyte proliferationGO:007066110.018
regulation of cell communicationGO:00106462320.018
single organism nuclear importGO:190259330.017
nucleoside monophosphate catabolic processGO:000912540.017
protein acylationGO:004354330.017
gtp metabolic processGO:004603940.017
cellular response to chemical stimulusGO:00708871570.017
meiotic cell cycle processGO:190304630.017
protein targeting to nucleusGO:004474430.017
positive regulation of cytosolic calcium ion concentrationGO:000720440.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
peptide metabolic processGO:000651810.017
endosomal transportGO:001619720.017
regulation of protein modification by small protein conjugation or removalGO:190332030.017
chordate embryonic developmentGO:00430092710.017
response to external stimulusGO:00096052640.017
protein localization to plasma membraneGO:007265910.017
response to organic substanceGO:00100331530.017
determination of bilateral symmetryGO:00098552040.017
eye developmentGO:00016542770.017
central nervous system developmentGO:00074173870.017
stem cell proliferationGO:007208940.017
negative regulation of protein localization to nucleusGO:190018120.017
peptidyl lysine acetylationGO:001839420.017
transmembrane transportGO:00550851200.017
regulation of signal transductionGO:00099662250.017
neuron projection morphogenesisGO:00488121610.017
antimicrobial humoral responseGO:001973020.016
regulation of protein complex assemblyGO:004325430.016
lateral inhibitionGO:004633110.016
membrane fusionGO:006102520.016
regulation of ion transmembrane transporter activityGO:003241220.016
regulation of sequestering of calcium ionGO:005128240.016
cellular response to extracellular stimulusGO:003166820.016
sequestering of calcium ionGO:005120830.016
internal peptidyl lysine acetylationGO:001839320.016
regulation of signalingGO:00230512350.016
regulation of synapse organizationGO:005080730.016
amino acid transportGO:000686520.016
protein import into nucleusGO:000660630.016
exocytosisGO:000688710.016
organelle fusionGO:004828430.016
blood vessel developmentGO:00015682460.016
negative regulation of sequestering of calcium ionGO:005128340.016
localization of cellGO:00516742440.016
single organism organelle organizationGO:19025891990.016
negative regulation of protein transportGO:005122430.016
positive regulation of cell activationGO:005086710.016
rna localizationGO:000640340.016
cell morphogenesis involved in differentiationGO:00009041950.015
neuron neuron synaptic transmissionGO:000727010.015
chemosensory behaviorGO:000763510.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
specification of symmetryGO:00097992040.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
cytoplasm organizationGO:000702840.015
ion transmembrane transportGO:0034220910.015
organic acid catabolic processGO:001605430.015
negative regulation of nuclear divisionGO:005178430.015
positive regulation of cellular catabolic processGO:003133130.015
positive regulation of secretionGO:005104710.015
single organism membrane fusionGO:004480120.015
post embryonic organ developmentGO:004856940.015
regulation of synapse assemblyGO:005196330.015
translational initiationGO:000641330.015
negative regulation of metabolic processGO:0009892860.015
synaptic vesicle localizationGO:009747910.015
erk1 and erk2 cascadeGO:007037140.015
locomotor rhythmGO:004547530.015
blood vessel morphogenesisGO:00485142160.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
cellular response to external stimulusGO:007149620.015
sequestering of metal ionGO:005123830.015
alcohol biosynthetic processGO:004616520.015
digestive tract morphogenesisGO:00485462310.015
cellular protein metabolic processGO:00442671290.015
regulation of protein targetingGO:190353320.015
regulation of purine nucleotide catabolic processGO:003312120.015
ion transportGO:00068111140.015
determination of left right symmetryGO:00073681790.015
digestive tract developmentGO:00485652650.015
head developmentGO:00603223030.015
regulation of protein catabolic processGO:004217610.014
negative regulation of mapk cascadeGO:004340940.014
compound eye developmentGO:004874920.014
mitochondrion organizationGO:000700540.014
cellular response to radiationGO:007147840.014
germ line stem cell maintenanceGO:003071820.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
positive regulation of protein complex assemblyGO:003133420.014
cell cycle g1 s phase transitionGO:004484310.014
single fertilizationGO:000733830.014
positive regulation of cytoskeleton organizationGO:005149530.014
neuron projection developmentGO:00311751800.014
regionalizationGO:00030022740.014
cellular response to lipopolysaccharideGO:007122230.014
embryonic organ morphogenesisGO:00485622740.014
regulation of neurotransmitter transportGO:005158810.014
regulation of dendrite developmentGO:005077330.014
female gonad developmentGO:000858540.014
developmental programmed cell deathGO:001062340.014
centrosome organizationGO:005129710.014
convergent extension involved in gastrulationGO:0060027710.014
oocyte anterior posterior axis specificationGO:000731440.014
phagocytosis engulfmentGO:000691110.014
hemopoiesisGO:00300971830.014
regulation of protein ubiquitinationGO:003139630.014
response to other organismGO:0051707970.014
lymphocyte proliferationGO:004665110.014
cellular response to organic substanceGO:00713101050.014
negative regulation of cytoplasmic transportGO:190365020.013
cellular response to nutrient levelsGO:003166920.013
regulation of carbohydrate metabolic processGO:000610940.013
regulation of nucleoside metabolic processGO:000911820.013
camera type eye developmentGO:00430102220.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
regulation of erk1 and erk2 cascadeGO:007037240.013
regulation of protein import into nucleusGO:004230620.013
deathGO:00162651210.013
regulation of dna replicationGO:000627530.013
actin filament polymerizationGO:003004120.013
adherens junction organizationGO:003433240.013
phosphate containing compound metabolic processGO:00067961080.013
response to external biotic stimulusGO:0043207970.013
regulation of autophagyGO:001050630.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
axon developmentGO:00615641660.013
regulation of nucleotide catabolic processGO:003081120.013
purine nucleoside monophosphate catabolic processGO:000912840.013
response to hexoseGO:000974630.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
interspecies interaction between organismsGO:004441940.013
regulation of multicellular organismal processGO:00512392770.013
response to monosaccharideGO:003428430.013
protein polymerizationGO:005125840.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
regulation of jak stat cascadeGO:004642530.013
regulation of cell differentiationGO:00455951420.013
positive regulation of secretion by cellGO:190353210.013
multi organism processGO:00517041340.013
striated muscle cell developmentGO:00550021080.013
brain developmentGO:00074202930.013
negative regulation of macromolecule metabolic processGO:0010605760.013
negative regulation of cytokine productionGO:000181810.013
ameboidal type cell migrationGO:00016671430.013
phosphorus metabolic processGO:00067931090.013
protein homooligomerizationGO:005126030.013
small molecule catabolic processGO:004428230.013
homeostatic processGO:00425921420.013
membrane invaginationGO:001032410.013
negative regulation of reproductive processGO:200024230.012
protein secretionGO:000930610.012
carbohydrate biosynthetic processGO:001605110.012
protein stabilizationGO:005082120.012
cell morphogenesis involved in neuron differentiationGO:00486671630.012
establishment of synaptic vesicle localizationGO:009748010.012
development of primary female sexual characteristicsGO:004654540.012
growthGO:00400071740.012
somatic muscle developmentGO:000752540.012
regulation of inflammatory responseGO:005072720.012
angiogenesisGO:00015251580.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
er to golgi vesicle mediated transportGO:000688810.012
response to glucoseGO:000974930.012
immune system developmentGO:00025201910.012
cellular response to biotic stimulusGO:007121630.012
apoptotic processGO:00069151160.012
release of sequestered calcium ion into cytosolGO:005120930.012
lipid homeostasisGO:005508830.012
mitochondrial transportGO:000683920.012
sensory perception of chemical stimulusGO:000760630.012
cellular component biogenesisGO:00440851780.012
regulation of gtpase activityGO:004308720.012
protein modification processGO:00362111000.012
regulation of transporter activityGO:003240920.012
synaptic vesicle transportGO:004848910.012
mesenchyme developmentGO:00604851270.012
positive regulation of nucleoside metabolic processGO:004597910.012
macromolecule modificationGO:00434121110.012
regulation of neurotransmitter secretionGO:004692810.012
skeletal system developmentGO:00015011810.012
muscle cell developmentGO:00550011150.012
actin polymerization or depolymerizationGO:000815420.012
regulation of mrna processingGO:005068430.012
regulation of calcium ion transportGO:005192420.012
positive regulation of histone modificationGO:003105810.012
epithelial tube morphogenesisGO:00605621480.012
eye morphogenesisGO:00485921440.012
g1 s transition of mitotic cell cycleGO:000008210.011
regulation of cellular carbohydrate metabolic processGO:001067540.011
positive regulation of cell divisionGO:005178120.011
g protein coupled receptor signaling pathwayGO:0007186740.011
macromolecular complex disassemblyGO:003298410.011
cell deathGO:00082191210.011
positive regulation of immune effector processGO:000269930.011
regulation of neural precursor cell proliferationGO:200017730.011
response to endogenous stimulusGO:0009719830.011
pole plasm assemblyGO:000731540.011
cell substrate adhesionGO:003158940.011
cellular protein modification processGO:00064641000.011
positive regulation of chromosome organizationGO:200125210.011
axonogenesisGO:00074091520.011
cation transportGO:0006812810.011
intracellular mrna localizationGO:000829810.011
positive regulation of dna metabolic processGO:005105410.011
meiotic chromosome segregationGO:004513230.011
stem cell divisionGO:001714510.011
gastrulationGO:00073692080.011
cytokinetic processGO:003250620.011
carbohydrate homeostasisGO:003350010.011
secondary metabolic processGO:001974830.011
spermatid differentiationGO:004851520.011
regulation of cell shapeGO:000836010.011
negative regulation of defense responseGO:003134820.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
dorsal ventral pattern formationGO:00099531250.011
determination of heart left right asymmetryGO:00613711170.011
regulation of anatomical structure morphogenesisGO:00226031300.011
epithelial cell differentiationGO:00308551160.011
organelle assemblyGO:00709251100.011
muscle cell differentiationGO:00426921390.011
positive regulation of nucleotide catabolic processGO:003081310.011
intracellular signal transductionGO:0035556850.011
regulation of chromosome segregationGO:005198310.011
ovulation cycleGO:004269820.011
vacuolar transportGO:000703420.011
response to uvGO:000941130.011
regulation of dendrite morphogenesisGO:004881430.011
negative regulation of intracellular transportGO:003238730.011
positive regulation of cytokine productionGO:000181920.011
chemotaxisGO:00069351040.011
negative regulation of map kinase activityGO:004340720.011
positive regulation of metabolic processGO:00098931080.011
developmental growthGO:00485891660.011
cellular lipid catabolic processGO:004424230.011
response to biotic stimulusGO:0009607970.011
segmentationGO:0035282970.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
regulation of translational initiationGO:000644610.011
neuroblast proliferationGO:000740520.011
striated muscle cell differentiationGO:00511461290.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
cellular response to oxygen levelsGO:007145310.011
regulation of stem cell proliferationGO:007209120.011
muscle organ developmentGO:00075171010.011
negative regulation of multi organism processGO:004390130.011
negative regulation of cellular metabolic processGO:0031324770.010
cell cycleGO:0007049930.010
cytosolic calcium ion transportGO:006040130.010
phosphatidylinositol 3 kinase signalingGO:001406520.010
positive regulation of chromatin modificationGO:190331010.010
production of molecular mediator of immune responseGO:000244020.010
negative regulation of intracellular protein transportGO:009031730.010
cellular component assemblyGO:00226071700.010
striated muscle tissue developmentGO:00147061100.010
cellular response to molecule of bacterial originGO:007121930.010
carboxylic acid catabolic processGO:004639530.010
cellular component disassemblyGO:002241110.010
regulation of gtp catabolic processGO:003312420.010
spermatid developmentGO:000728620.010
negative regulation of nucleocytoplasmic transportGO:004682320.010
mitotic cytokinesisGO:000028130.010
glucose homeostasisGO:004259310.010
negative regulation of gene expressionGO:0010629650.010
myeloid cell differentiationGO:0030099860.010
cellular localizationGO:0051641970.010
cellular component assembly involved in morphogenesisGO:00109271070.010
regulation of cell developmentGO:00602841000.010
sensory organ morphogenesisGO:00905962000.010
protein dephosphorylationGO:000647030.010
b cell activationGO:004211320.010
calcium ion transport into cytosolGO:006040230.010

spo11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.045
musculoskeletal system diseaseDOID:1700.023
nervous system diseaseDOID:86300.018
muscular diseaseDOID:008000000.012
muscle tissue diseaseDOID:6600.012
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
disease of metabolismDOID:001466700.010