Danio rerio

24 known processes

ptprea

protein tyrosine phosphatase, receptor type, E, a

ptprea biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
gastrulationGO:00073692080.206
convergent extension involved in gastrulationGO:0060027710.128
lateral inhibitionGO:004633110.115
Fly
digestive system developmentGO:00551232890.111
digestive tract developmentGO:00485652650.110
convergent extensionGO:00600261180.105
morphogenesis of an epitheliumGO:00020093330.100
larval developmentGO:000216420.088
regulation of cell projection assemblyGO:006049140.072
cell projection morphogenesisGO:00488582440.071
Fly
protein dephosphorylationGO:000647030.071
Mouse Fly
cellular macromolecule metabolic processGO:00442603910.069
Zebrafish Mouse Fly
actin polymerization or depolymerizationGO:000815420.067
digestive tract morphogenesisGO:00485462310.065
regulation of cellular metabolic processGO:00313233200.059
Zebrafish
regulation of stem cell differentiationGO:200073640.057
regulation of protein transportGO:005122330.053
regulation of metabolic processGO:00192223590.053
Zebrafish
negative regulation of protein transportGO:005122430.053
phosphorus metabolic processGO:00067931090.053
Zebrafish Mouse Fly
response to external stimulusGO:00096052640.050
Fly
motor neuron axon guidanceGO:0008045230.048
Fly
protein polymerizationGO:005125840.047
cell surface receptor signaling pathwayGO:00071663250.046
Mouse
retina development in camera type eyeGO:00600411460.046
Zebrafish
response to chemicalGO:00422213200.046
Mouse Fly
regulation of reproductive processGO:200024140.043
protein localization to nucleusGO:003450430.042
regulation of synapse assemblyGO:005196330.042
phosphate containing compound metabolic processGO:00067961080.041
Zebrafish Mouse Fly
positive regulation of blood circulationGO:190352420.039
nucleocytoplasmic transportGO:000691340.039
agingGO:000756820.039
nuclear transportGO:005116940.039
regulation of synapse organizationGO:005080730.038
cellular component movementGO:00069283350.038
Fly
embryonic organ morphogenesisGO:00485622740.037
specification of symmetryGO:00097992040.037
sensory organ developmentGO:00074233930.036
Zebrafish
regulation of cytoplasmic transportGO:190364940.036
tissue remodelingGO:004877140.035
regulation of establishment of protein localizationGO:007020140.035
response to organic substanceGO:00100331530.035
Mouse
generation of neuronsGO:00486993850.034
Fly
protein metabolic processGO:00195381830.034
Zebrafish Mouse Fly
neuron projection morphogenesisGO:00488121610.034
Fly
neuron developmentGO:00486662620.033
Fly
axon developmentGO:00615641660.033
Fly
anterior posterior pattern specificationGO:00099521520.033
neuron projection developmentGO:00311751800.033
Fly
protein targeting to nucleusGO:004474430.033
negative regulation of stem cell differentiationGO:200073720.032
cellular component morphogenesisGO:00329893360.032
Fly
cellular response to external stimulusGO:007149620.032
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.032
positive regulation of cellular component biogenesisGO:004408930.031
regulation of primary metabolic processGO:00800903110.031
Zebrafish
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.031
endocrine processGO:005088620.031
positive regulation of protein complex assemblyGO:003133420.030
exocytosisGO:000688710.030
zymogen activationGO:003163830.029
maintenance of locationGO:005123540.029
immune system processGO:00023762410.029
Mouse
gland developmentGO:00487321430.029
synaptic growth at neuromuscular junctionGO:005112420.028
regulation of protein localization to nucleusGO:190018020.028
inositol lipid mediated signalingGO:004801720.028
protein importGO:001703830.028
biosynthetic processGO:00090582940.028
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.028
Mouse
positive regulation of cytokine productionGO:000181920.028
regulation of synaptic growth at neuromuscular junctionGO:000858210.028
regulation of protein complex assemblyGO:004325430.027
multicellular organismal metabolic processGO:004423620.027
cellular amine metabolic processGO:004410620.027
camera type eye developmentGO:00430102220.027
Zebrafish
determination of left right symmetryGO:00073681790.027
negative regulation of protein phosphorylationGO:000193340.027
regulation of cellular amino acid metabolic processGO:000652100.027
response to other organismGO:0051707970.027
negative regulation of kinase activityGO:003367340.027
cell part morphogenesisGO:00329902460.027
Fly
embryonic organ developmentGO:00485683810.027
phagocytosisGO:000690930.027
cellular biosynthetic processGO:00442492860.026
regulation of protein polymerizationGO:003227120.026
single organism localizationGO:19025782250.026
chordate embryonic developmentGO:00430092710.026
positive regulation of cellular catabolic processGO:003133130.026
embryonic skeletal system morphogenesisGO:0048704930.026
positive regulation of transportGO:005105020.026
regulation of blood pressureGO:000821710.026
amine metabolic processGO:000930820.026
cellular protein metabolic processGO:00442671290.025
Zebrafish Mouse Fly
cell projection organizationGO:00300302840.025
Fly
regulation of cytokine productionGO:000181730.025
negative regulation of cellular processGO:00485232830.025
Mouse
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.025
regulation of catalytic activityGO:0050790550.025
Zebrafish
tube morphogenesisGO:00352393490.025
fertilizationGO:000956630.024
protein import into nucleusGO:000660630.024
regulation of wound healingGO:006104120.024
guanosine containing compound catabolic processGO:190106920.024
proteolysis involved in cellular protein catabolic processGO:005160330.024
multicellular organism growthGO:003526440.024
phosphatidylinositol mediated signalingGO:004801520.023
regulation of filopodium assemblyGO:005148920.023
phosphatidylinositol 3 kinase signalingGO:001406520.023
guanosine containing compound metabolic processGO:190106840.023
modification dependent protein catabolic processGO:001994130.023
regulation of cell communicationGO:00106462320.023
Mouse
regionalizationGO:00030022740.023
regulation of cell shapeGO:000836010.023
peptidyl threonine phosphorylationGO:001810710.023
regulation of rho protein signal transductionGO:003502320.023
positive regulation of cytoskeleton organizationGO:005149530.023
cell migrationGO:00164772370.023
taxisGO:00423301090.023
Fly
positive regulation of small gtpase mediated signal transductionGO:005105710.023
cell motilityGO:00488702440.022
organic substance biosynthetic processGO:19015762890.022
nuclear importGO:005117030.022
single organism metabolic processGO:00447102170.022
muscle structure developmentGO:00610611960.022
establishment of protein localization to organelleGO:007259440.022
regulation of blood vessel sizeGO:005088020.022
regulation of nucleocytoplasmic transportGO:004682220.022
lipid storageGO:001991510.022
regulation of blood coagulationGO:003019310.022
stem cell differentiationGO:00488631170.022
protein secretionGO:000930610.022
positive regulation of erk1 and erk2 cascadeGO:007037420.022
regulation of protein targetingGO:190353320.021
positive regulation of immune effector processGO:000269930.021
erk1 and erk2 cascadeGO:007037140.021
nuclear migrationGO:000709730.021
regulation of macromolecule metabolic processGO:00602553170.021
Zebrafish
regulation of biosynthetic processGO:00098892500.021
neuron differentiationGO:00301823530.021
Fly
positive regulation of catabolic processGO:000989640.021
positive regulation of protein polymerizationGO:003227320.021
single organism nuclear importGO:190259330.021
single fertilizationGO:000733830.021
vasculature developmentGO:00019442780.021
cellular component disassemblyGO:002241110.021
macromolecule modificationGO:00434121110.020
Zebrafish Mouse Fly
negative regulation of biological processGO:00485193040.020
Mouse
adult behaviorGO:003053420.020
regulation of tube sizeGO:003515020.020
cellular nitrogen compound metabolic processGO:00346412900.020
positive regulation of cell cycleGO:004578730.020
positive regulation of cytosolic calcium ion concentrationGO:000720440.020
regulation of phosphorus metabolic processGO:0051174430.020
Zebrafish
negative regulation of protein kinase activityGO:000646940.020
axon guidanceGO:0007411860.020
Fly
regulation of exocytosisGO:001715710.020
symbiosis encompassing mutualism through parasitismGO:004440340.020
positive regulation of cellular amino acid metabolic processGO:004576400.020
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.020
regulation of purine nucleotide catabolic processGO:003312120.020
positive regulation of stress activated mapk cascadeGO:003287430.020
embryo development ending in birth or egg hatchingGO:00097922710.019
enzyme linked receptor protein signaling pathwayGO:00071671060.019
Mouse
phosphorylationGO:0016310690.019
Zebrafish
regulation of intracellular protein transportGO:003315730.019
regulation of erk1 and erk2 cascadeGO:007037240.019
cellular response to extracellular stimulusGO:003166820.019
regulation of biological qualityGO:00650082630.019
axonal defasciculationGO:000741420.019
Fly
membrane invaginationGO:001032410.019
protein complex disassemblyGO:004324110.019
regulation of oocyte developmentGO:006028130.019
peptidyl tyrosine dephosphorylationGO:003533510.019
Mouse Fly
organonitrogen compound metabolic processGO:1901564740.019
positive regulation of secretionGO:005104710.019
negative regulation of cytoplasmic transportGO:190365020.019
gtp metabolic processGO:004603940.019
blood vessel developmentGO:00015682460.019
small molecule metabolic processGO:0044281770.018
segmentationGO:0035282970.018
positive regulation of secretion by cellGO:190353210.018
heterocycle metabolic processGO:00464832900.018
response to external biotic stimulusGO:0043207970.018
gtp catabolic processGO:000618420.018
regulation of endocrine processGO:004406020.018
stem cell divisionGO:001714510.018
skeletal system developmentGO:00015011810.018
interspecies interaction between organismsGO:004441940.018
negative regulation of nucleocytoplasmic transportGO:004682320.018
cellular amino acid metabolic processGO:000652070.018
kupffer s vesicle developmentGO:0070121500.018
alcohol biosynthetic processGO:004616520.018
response to carbohydrateGO:000974330.018
cell morphogenesis involved in differentiationGO:00009041950.018
Fly
phagocytosis engulfmentGO:000691110.018
peptidyl threonine modificationGO:001821010.018
neurological system processGO:0050877620.018
protein phosphorylationGO:0006468470.018
Zebrafish
cellular response to chemical stimulusGO:00708871570.018
Mouse
autophagyGO:000691440.017
rho protein signal transductionGO:000726650.017
germ line stem cell maintenanceGO:003071820.017
regulation of cellular amine metabolic processGO:003323800.017
system processGO:00030081850.017
regulation of dendrite developmentGO:005077330.017
nitrogen compound metabolic processGO:00068073190.017
synaptic vesicle localizationGO:009747910.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of multicellular organism growthGO:004001440.017
negative regulation of intracellular transportGO:003238730.017
superoxide metabolic processGO:000680120.017
regulation of response to stimulusGO:00485832690.017
Mouse
localization of cellGO:00516742440.017
positive regulation of nitrogen compound metabolic processGO:0051173690.017
response to stressGO:00069502630.017
g1 s transition of mitotic cell cycleGO:000008210.017
protein modification processGO:00362111000.017
Zebrafish Mouse Fly
small gtpase mediated signal transductionGO:000726480.017
response to glucoseGO:000974930.017
response to woundingGO:00096111160.017
modification dependent macromolecule catabolic processGO:004363230.017
signal transductionGO:00071654550.017
Mouse
cellular response to hormone stimulusGO:0032870390.016
Mouse
response to biotic stimulusGO:0009607970.016
developmental programmed cell deathGO:001062340.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
regulation of protein import into nucleusGO:004230620.016
negative regulation of protein serine threonine kinase activityGO:007190120.016
regulation of nucleoside metabolic processGO:000911820.016
mitochondrion organizationGO:000700540.016
collagen metabolic processGO:003296320.016
wound healingGO:0042060900.016
negative regulation of intracellular protein transportGO:009031730.016
brain developmentGO:00074202930.016
regulation of glomerular filtrationGO:000309310.016
renal system process involved in regulation of blood volumeGO:000197710.016
cell substrate adhesionGO:003158940.016
cortical actin cytoskeleton organizationGO:003086610.015
regulation of phosphate metabolic processGO:0019220430.015
Zebrafish
heart morphogenesisGO:00030071560.015
positive regulation of map kinase activityGO:004340630.015
regulation of jak stat cascadeGO:004642530.015
nucleobase containing compound metabolic processGO:00061392740.015
g protein coupled receptor signaling pathwayGO:0007186740.015
cytosolic calcium ion transportGO:006040130.015
sensory perception of chemical stimulusGO:000760630.015
cellular macromolecule biosynthetic processGO:00346452240.015
cellular response to starvationGO:000926710.015
regulation of gtp catabolic processGO:003312420.015
skeletal system morphogenesisGO:00487051020.015
head developmentGO:00603223030.015
cellular response to nutrient levelsGO:003166920.015
actin filament based movementGO:003004810.015
gene expressionGO:00104672520.015
positive regulation of epithelial cell proliferationGO:005067910.015
stem cell maintenanceGO:001982740.015
cilium morphogenesisGO:0060271850.015
multicellular organismal response to stressGO:003355520.015
regulation of hematopoietic progenitor cell differentiationGO:190153210.015
cellular protein catabolic processGO:004425740.015
rna metabolic processGO:00160702190.015
cellular localizationGO:0051641970.015
regulation of cellular ketone metabolic processGO:001056570.015
multi organism processGO:00517041340.014
negative regulation of map kinase activityGO:004340720.014
regulation of systemic arterial blood pressureGO:000307310.014
establishment of localization in cellGO:0051649770.014
cellular aromatic compound metabolic processGO:00067252950.014
cell recognitionGO:0008037190.014
Fly
macromolecule biosynthetic processGO:00090592270.014
determination of bilateral symmetryGO:00098552040.014
tyrosine phosphorylation of stat proteinGO:000726010.014
regenerationGO:0031099910.014
regulation of epithelial cell proliferationGO:005067830.014
apoptotic process involved in developmentGO:190274220.014
regulation of inflammatory responseGO:005072720.014
negative regulation of mapk cascadeGO:004340940.014
response to monosaccharideGO:003428430.014
negative regulation of cytokine productionGO:000181810.014
positive regulation of nucleoside metabolic processGO:004597910.014
atp catabolic processGO:000620040.014
regulation of metal ion transportGO:001095940.014
response to hexoseGO:000974630.014
regulation of muscle contractionGO:000693730.014
hemopoiesisGO:00300971830.014
i kappab kinase nf kappab signalingGO:000724940.014
regulation of microtubule cytoskeleton organizationGO:007050730.014
catecholamine metabolic processGO:000658420.014
carbohydrate derivative metabolic processGO:1901135610.014
mesenchyme developmentGO:00604851270.014
myeloid leukocyte mediated immunityGO:000244410.014
cellular response to endogenous stimulusGO:0071495680.014
Mouse
cytokinesisGO:000091030.014
ribonucleoside monophosphate catabolic processGO:000915840.014
negative regulation of protein import into nucleusGO:004230820.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
macroautophagyGO:001623610.014
multicellular organismal macromolecule metabolic processGO:004425920.013
heart developmentGO:00075073130.013
rna localizationGO:000640340.013
negative regulation of ras protein signal transductionGO:004658010.013
cognitionGO:005089010.013
regulation of bindingGO:005109830.013
sensory perceptionGO:0007600390.013
establishment of endothelial barrierGO:006102830.013
single organism organelle organizationGO:19025891990.013
organic cyclic compound metabolic processGO:19013603010.013
divalent inorganic cation homeostasisGO:0072507220.013
protein localization to plasma membraneGO:007265910.013
regulation of organ growthGO:004662030.013
protein depolymerizationGO:005126110.013
nuclear exportGO:005116810.013
sequestering of metal ionGO:005123830.013
developmental growthGO:00485891660.013
primary neural tube formationGO:001402010.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
regulation of oligodendrocyte differentiationGO:004871310.013
ubiquitin dependent protein catabolic processGO:000651130.013
production of molecular mediator of immune responseGO:000244020.013
regulation of multicellular organismal processGO:00512392770.013
detection of stimulus involved in sensory perceptionGO:0050906210.013
growthGO:00400071740.013
tissue regenerationGO:0042246740.013
extrinsic apoptotic signaling pathwayGO:009719130.013
organelle organizationGO:00069962270.013
regulation of dendrite morphogenesisGO:004881430.013
cell cycle g1 s phase transitionGO:004484310.013
positive regulation of jnk cascadeGO:004633030.013
maternal determination of anterior posterior axis embryoGO:000835840.013
regulation of nucleotide catabolic processGO:003081120.013
cellular response to organic substanceGO:00713101050.013
Mouse
cellular ketone metabolic processGO:0042180110.012
sensory perception of painGO:001923310.012
regulation of protein complex disassemblyGO:004324410.012
purine nucleoside monophosphate catabolic processGO:000912840.012
post embryonic organ developmentGO:004856940.012
regulation of autophagyGO:001050630.012
calcium ion transport into cytosolGO:006040230.012
striated muscle tissue developmentGO:00147061100.012
cell morphogenesisGO:00009022890.012
Fly
regulation of gtpase activityGO:004308720.012
oxoacid metabolic processGO:0043436310.012
determination of heart left right asymmetryGO:00613711170.012
positive regulation of gtp catabolic processGO:003312610.012
heterocycle biosynthetic processGO:00181302150.012
positive regulation of cell adhesionGO:004578510.012
negative regulation of secretionGO:005104820.012
positive regulation of gtpase activityGO:004354710.012
regulation of signal transductionGO:00099662250.012
Mouse
positive regulation of multi organism processGO:004390230.012
regulation of glial cell differentiationGO:004568540.012
regulation of multicellular organismal developmentGO:20000262230.012
cellular protein complex disassemblyGO:004362410.012
cellular response to oxygen levelsGO:007145310.012
antimicrobial humoral responseGO:001973020.012
glucose homeostasisGO:004259310.012
regulation of macromolecule biosynthetic processGO:00105562250.012
establishment of protein localization to plasma membraneGO:009000210.012
negative regulation of signal transductionGO:0009968940.012
Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.012
leukocyte proliferationGO:007066110.012
neuroblast proliferationGO:000740520.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
neurotransmitter transportGO:000683620.012
cellular response to decreased oxygen levelsGO:003629410.012
collagen biosynthetic processGO:003296420.012
golgi vesicle transportGO:004819330.012
negative regulation of catabolic processGO:000989530.012
ameboidal type cell migrationGO:00016671430.012
cellular response to radiationGO:007147840.012
positive regulation of nucleotide catabolic processGO:003081310.012
positive regulation of jak stat cascadeGO:004642720.012
somatic muscle developmentGO:000752540.011
regulation of calcium ion transportGO:005192420.011
positive regulation of wound healingGO:009030310.011
negative regulation of cellular catabolic processGO:003133030.011
synaptic vesicle transportGO:004848910.011
somite developmentGO:0061053960.011
muscle cell differentiationGO:00426921390.011
positive regulation of ras gtpase activityGO:003232010.011
positive regulation of rho protein signal transductionGO:003502500.011
blood vessel morphogenesisGO:00485142160.011
ras protein signal transductionGO:000726570.011
centrosome organizationGO:005129710.011
transportGO:00068102200.011
regulation of molecular functionGO:0065009700.011
Zebrafish
nucleobase containing compound biosynthetic processGO:00346542050.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
organic acid metabolic processGO:0006082310.011
single organism transportGO:00447652060.011
response to glucocorticoidGO:005138410.011
embryonic heart tube developmentGO:00350501330.011
circulatory system processGO:0003013870.011
negative regulation of protein localization to nucleusGO:190018120.011
organic cyclic compound biosynthetic processGO:19013622230.011
ventricular cardiac muscle tissue morphogenesisGO:005501020.011
positive regulation of cell activationGO:005086710.011
urogenital system developmentGO:0001655970.011
negative regulation of synapse assemblyGO:005196420.011
regulation of multicellular organismal metabolic processGO:004424620.011
positive regulation of leukocyte migrationGO:000268720.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
adherens junction organizationGO:003433240.011
regulation of protein metabolic processGO:0051246560.011
Zebrafish
endosomal transportGO:001619720.011
endocardium morphogenesisGO:000316040.011
sensory perception of smellGO:000760820.011
ion homeostasisGO:0050801410.011
morphogenesis of an epithelial sheetGO:0002011490.011
negative regulation of multi organism processGO:004390130.011
regulation of response to biotic stimulusGO:000283120.011
cell cell signaling involved in cell fate commitmentGO:0045168120.011
Fly
response to alkaloidGO:004327920.011
calcium ion dependent exocytosisGO:001715610.011
macromolecular complex disassemblyGO:003298410.010
actin mediated cell contractionGO:007025210.010
stem cell proliferationGO:007208940.010
immune system developmentGO:00025201910.010
regulation of dna replicationGO:000627530.010
aromatic compound biosynthetic processGO:00194382170.010
establishment of localizationGO:00512342440.010
peptide transportGO:001583310.010
negative regulation of defense responseGO:003134820.010
membrane hyperpolarizationGO:006008110.010
nucleoside monophosphate catabolic processGO:000912540.010
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.010
post golgi vesicle mediated transportGO:000689210.010
microtubule polymerizationGO:004678520.010
leukocyte mediated cytotoxicityGO:000190910.010
negative regulation of chemotaxisGO:005092240.010

ptprea disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.023
disease of anatomical entityDOID:700.019
eye diseaseDOID:561400.018
eye and adnexa diseaseDOID:149200.018
sensory system diseaseDOID:005015500.018
nervous system diseaseDOID:86300.018
retinal diseaseDOID:567900.011
disease of cellular proliferationDOID:1456600.011