Danio rerio

0 known processes

LOC100004946

transient receptor potential cation channel subfamily M member 4-like

LOC100004946 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of biosynthetic processGO:00098892500.238
cellular carbohydrate metabolic processGO:004426240.197
regulation of cellular macromolecule biosynthetic processGO:20001122220.187
response to drugGO:004249330.166
cellular biosynthetic processGO:00442492860.161
positive regulation of biological processGO:00485182530.152
cellular macromolecule metabolic processGO:00442603910.131
symbiosis encompassing mutualism through parasitismGO:004440340.123
regulation of macromolecule biosynthetic processGO:00105562250.116
response to mechanical stimulusGO:0009612240.105
response to stressGO:00069502630.104
agingGO:000756820.103
homeostatic processGO:00425921420.094
heterocycle biosynthetic processGO:00181302150.092
regulation of cytokine productionGO:000181730.091
regulation of biological qualityGO:00650082630.090
regulation of i kappab kinase nf kappab signalingGO:004312240.089
cellular nitrogen compound biosynthetic processGO:00442712180.089
regulation of production of molecular mediator of immune responseGO:000270010.088
regulation of nitrogen compound metabolic processGO:00511712510.086
ion transportGO:00068111140.084
biosynthetic processGO:00090582940.084
rna biosynthetic processGO:00327741810.083
response to virusGO:0009615210.079
cellular response to external stimulusGO:007149620.076
response to light stimulusGO:0009416460.076
leukocyte proliferationGO:007066110.075
heterocycle metabolic processGO:00464832900.074
regulation of cellular biosynthetic processGO:00313262450.074
ion transmembrane transportGO:0034220910.073
cellular response to nutrient levelsGO:003166920.073
response to abiotic stimulusGO:00096281220.072
blood vessel developmentGO:00015682460.072
positive regulation of cellular component biogenesisGO:004408930.072
regulation of cellular metabolic processGO:00313233200.069
membrane lipid biosynthetic processGO:004646720.068
nucleobase containing compound biosynthetic processGO:00346542050.067
aromatic compound biosynthetic processGO:00194382170.067
cellular aromatic compound metabolic processGO:00067252950.066
transcription dna templatedGO:00063511810.065
positive regulation of nitrogen compound metabolic processGO:0051173690.065
positive regulation of cell activationGO:005086710.064
defense response to other organismGO:0098542330.063
positive regulation of i kappab kinase nf kappab signalingGO:004312330.062
positive regulation of immune effector processGO:000269930.059
regulation of macromolecule metabolic processGO:00602553170.058
organic substance biosynthetic processGO:19015762890.057
cellular macromolecule biosynthetic processGO:00346452240.057
signal transductionGO:00071654550.057
regulation of cellular carbohydrate metabolic processGO:001067540.056
regulation of gene expressionGO:00104682650.056
establishment of localizationGO:00512342440.055
positive regulation of cytokine productionGO:000181920.055
regulation of primary metabolic processGO:00800903110.054
extrinsic apoptotic signaling pathwayGO:009719130.053
positive regulation of cytosolic calcium ion concentrationGO:000720440.053
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.052
cellular nitrogen compound metabolic processGO:00346412900.052
response to nutrientGO:000758430.052
regulation of response to biotic stimulusGO:000283120.051
regulation of rna metabolic processGO:00512522240.051
camera type eye developmentGO:00430102220.051
immunoglobulin mediated immune responseGO:001606430.050
vasculogenesisGO:0001570410.050
tube morphogenesisGO:00352393490.049
determination of heart left right asymmetryGO:00613711170.049
positive regulation of transportGO:005105020.048
ameboidal type cell migrationGO:00016671430.048
regulation of extrinsic apoptotic signaling pathwayGO:200123630.046
cell motilityGO:00488702440.046
organic cyclic compound biosynthetic processGO:19013622230.046
striated muscle tissue developmentGO:00147061100.046
positive regulation of macromolecule metabolic processGO:0010604930.045
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.045
positive regulation of macromolecule biosynthetic processGO:0010557590.045
cellular response to lipopolysaccharideGO:007122230.043
production of molecular mediator of immune responseGO:000244020.043
response to chemicalGO:00422213200.043
blood vessel morphogenesisGO:00485142160.043
determination of left right symmetryGO:00073681790.042
i kappab kinase nf kappab signalingGO:000724940.042
type i interferon productionGO:003260620.042
nucleobase containing compound metabolic processGO:00061392740.042
striated muscle cell differentiationGO:00511461290.041
transportGO:00068102200.041
regulation of nucleic acid templated transcriptionGO:19035062130.041
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.041
regulation of cell communicationGO:00106462320.039
membrane lipid metabolic processGO:0006643100.039
single organism metabolic processGO:00447102170.039
positive regulation of biosynthetic processGO:0009891680.038
epithelial cell differentiationGO:00308551160.038
response to lipidGO:0033993600.038
nitrogen compound metabolic processGO:00068073190.038
interspecies interaction between organismsGO:004441940.037
regulation of rna biosynthetic processGO:20011412130.037
deathGO:00162651210.037
negative regulation of biological processGO:00485193040.037
specification of symmetryGO:00097992040.036
divalent inorganic cation transportGO:0072511210.036
xenobiotic metabolic processGO:000680540.036
mononuclear cell proliferationGO:003294310.035
digestive system developmentGO:00551232890.035
retina development in camera type eyeGO:00600411460.035
eye developmentGO:00016542770.035
cell proliferationGO:0008283800.035
system processGO:00030081850.034
cellular response to stressGO:0033554620.034
striated muscle cell developmentGO:00550021080.034
glycoprotein metabolic processGO:0009100230.034
organic cyclic compound metabolic processGO:19013603010.034
carbohydrate derivative metabolic processGO:1901135610.034
regulation of signal transductionGO:00099662250.033
regulation of protein import into nucleusGO:004230620.033
gtp metabolic processGO:004603940.033
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.032
cell surface receptor signaling pathwayGO:00071663250.032
vasculature developmentGO:00019442780.032
cellular response to extracellular stimulusGO:003166820.032
cell deathGO:00082191210.032
nucleic acid templated transcriptionGO:00976591810.032
muscle structure developmentGO:00610611960.032
regulation of carbohydrate metabolic processGO:000610940.032
cell cycle g1 s phase transitionGO:004484310.032
protein complex localizationGO:003150310.032
macromolecule biosynthetic processGO:00090592270.031
positive regulation of epithelial cell proliferationGO:005067910.031
immune responseGO:0006955280.031
sensory perception of painGO:001923310.031
morphogenesis of an epitheliumGO:00020093330.030
cell migrationGO:00164772370.030
regulation of synapse assemblyGO:005196330.030
transmembrane transportGO:00550851200.030
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.030
zymogen activationGO:003163830.030
regulation of nucleobase containing compound metabolic processGO:00192192500.029
regulation of cell activationGO:005086510.029
chemosensory behaviorGO:000763510.028
glycolipid metabolic processGO:000666480.028
urogenital system developmentGO:0001655970.028
regulation of tube sizeGO:003515020.028
guanosine containing compound catabolic processGO:190106920.028
heart developmentGO:00075073130.028
hemopoiesisGO:00300971830.028
viral processGO:001603210.028
regulation of inflammatory responseGO:005072720.028
immune system developmentGO:00025201910.028
response to organic cyclic compoundGO:0014070510.028
lymphocyte proliferationGO:004665110.027
positive regulation of cellular processGO:00485222010.027
regulation of bindingGO:005109830.027
regulation of establishment of protein localizationGO:007020140.027
regulation of metabolic processGO:00192223590.027
cellular amine metabolic processGO:004410620.027
multicellular organismal response to stressGO:003355520.027
regulation of dendrite morphogenesisGO:004881430.027
gene expressionGO:00104672520.027
positive regulation of secretionGO:005104710.026
regulation of synapse organizationGO:005080730.026
negative regulation of protein transportGO:005122430.026
positive regulation of endothelial cell migrationGO:001059520.026
regulation of intracellular signal transductionGO:1902531570.026
positive regulation of jnk cascadeGO:004633030.025
response to other organismGO:0051707970.025
myeloid cell homeostasisGO:0002262560.025
inorganic cation transmembrane transportGO:0098662500.025
positive regulation of epithelial cell migrationGO:001063420.025
regulation of protein complex assemblyGO:004325430.025
somatic muscle developmentGO:000752540.025
eye morphogenesisGO:00485921440.025
response to hydrogen peroxideGO:004254230.024
cellular component disassemblyGO:002241110.024
cellular response to starvationGO:000926710.024
organic acid metabolic processGO:0006082310.024
response to inorganic substanceGO:0010035380.024
regulation of circadian rhythmGO:004275240.024
carboxylic acid metabolic processGO:0019752220.024
rna metabolic processGO:00160702190.023
cellular component biogenesisGO:00440851780.023
carbohydrate derivative biosynthetic processGO:1901137430.023
immune system processGO:00023762410.023
regulation of cytokine biosynthetic processGO:004203510.023
muscle tissue developmentGO:00605371100.023
embryonic organ morphogenesisGO:00485622740.023
protein localization to nucleusGO:003450430.023
amine metabolic processGO:000930820.023
positive regulation of stress activated mapk cascadeGO:003287430.023
response to woundingGO:00096111160.022
hormone secretionGO:004687920.022
exocytosisGO:000688710.022
positive regulation of catabolic processGO:000989640.022
phototransductionGO:000760220.022
nucleic acid metabolic processGO:00903042440.022
transcription from rna polymerase ii promoterGO:0006366800.022
detection of external stimulusGO:0009581240.022
defense response to bacteriumGO:0042742220.022
cognitionGO:005089010.022
glycosylationGO:0070085110.022
regionalizationGO:00030022740.022
divalent metal ion transportGO:0070838200.022
guanosine containing compound metabolic processGO:190106840.022
regulation of autophagyGO:001050630.021
regulation of multicellular organismal processGO:00512392770.021
regulation of organ morphogenesisGO:2000027350.021
regulation of transcription dna templatedGO:00063552130.021
larval developmentGO:000216420.021
positive regulation of secretion by cellGO:190353210.021
epithelial tube morphogenesisGO:00605621480.021
rna stabilizationGO:004348940.021
apoptotic processGO:00069151160.021
cytokinesisGO:000091030.021
embryonic heart tube morphogenesisGO:00031431080.021
response to external stimulusGO:00096052640.021
muscle cell developmentGO:00550011150.021
cellular response to chemical stimulusGO:00708871570.020
cellular response to molecule of bacterial originGO:007121930.020
negative regulation of mapk cascadeGO:004340940.020
skeletal system developmentGO:00015011810.020
nitric oxide metabolic processGO:004620920.020
embryonic organ developmentGO:00485683810.020
single organism localizationGO:19025782250.020
fat soluble vitamin metabolic processGO:000677540.020
fluid transportGO:0042044170.020
regulation of blood pressureGO:000821710.019
organonitrogen compound metabolic processGO:1901564740.019
embryonic heart tube developmentGO:00350501330.019
response to coldGO:000940940.019
regulation of endothelial cell proliferationGO:000193610.019
single organism transportGO:00447652060.019
locomotionGO:00400113130.019
phosphatidylinositol 3 kinase signalingGO:001406520.019
positive regulation of cell cycleGO:004578730.019
response to alkaloidGO:004327920.019
cellular protein modification processGO:00064641000.019
regulation of intracellular protein transportGO:003315730.019
regulation of dendrite developmentGO:005077330.019
neural crest cell developmentGO:0014032620.019
activation of immune responseGO:000225390.019
endocrine processGO:005088620.019
small molecule metabolic processGO:0044281770.019
central nervous system developmentGO:00074173870.019
response to oxygen levelsGO:0070482250.018
cellular lipid metabolic processGO:0044255360.018
convergent extensionGO:00600261180.018
protein metabolic processGO:00195381830.018
cellular component assemblyGO:00226071700.018
regulation of protein catabolic processGO:004217610.018
regulation of cytoplasmic transportGO:190364940.018
nucleocytoplasmic transportGO:000691340.018
response to bacteriumGO:0009617580.018
positive regulation of cellular catabolic processGO:003133130.018
regulation of programmed cell deathGO:00430671010.018
positive regulation of purine nucleotide catabolic processGO:003312310.018
maintenance of locationGO:005123540.018
embryonic hemopoiesisGO:0035162530.018
response to radiationGO:0009314510.018
regulation of protein transportGO:005122330.017
regulation of system processGO:0044057400.017
myeloid cell differentiationGO:0030099860.017
protein import into nucleusGO:000660630.017
kidney developmentGO:0001822920.017
negative regulation of catabolic processGO:000989530.017
negative regulation of cellular metabolic processGO:0031324770.017
synaptic growth at neuromuscular junctionGO:005112420.017
nuclear transportGO:005116940.017
regulation of cell deathGO:00109411030.017
regulation of blood vessel sizeGO:005088020.017
cellular component morphogenesisGO:00329893360.017
autophagyGO:000691440.017
macromolecule modificationGO:00434121110.017
b cell mediated immunityGO:001972430.017
response to vitaminGO:003327330.017
response to oxidative stressGO:0006979110.017
positive regulation of nucleoside metabolic processGO:004597910.017
muscle cell differentiationGO:00426921390.017
cellular response to hypoxiaGO:007145610.017
response to metal ionGO:0010038340.017
chordate embryonic developmentGO:00430092710.016
regulation of protein localization to nucleusGO:190018020.016
sensory perceptionGO:0007600390.016
regulation of nucleocytoplasmic transportGO:004682220.016
b cell activationGO:004211320.016
response to carbohydrateGO:000974330.016
single organism membrane fusionGO:004480120.016
positive regulation of leukocyte differentiationGO:190210710.016
stem cell maintenanceGO:001982740.016
reactive oxygen species metabolic processGO:007259360.016
regulation of metal ion transportGO:001095940.016
gtp catabolic processGO:000618420.016
regulation of blood circulationGO:1903522320.016
water homeostasisGO:003010440.016
calcium ion transportGO:0006816180.016
negative regulation of cytokine productionGO:000181810.016
female sex differentiationGO:004666040.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.016
regulation of wound healingGO:006104120.016
response to monosaccharideGO:003428430.016
dna biosynthetic processGO:007189730.016
protein glycosylationGO:000648690.016
cellular response to biotic stimulusGO:007121630.016
erythrocyte homeostasisGO:0034101550.015
renal system developmentGO:0072001940.015
macromolecular complex subunit organizationGO:0043933740.015
mitochondrion organizationGO:000700540.015
gastrulationGO:00073692080.015
establishment of protein localization to organelleGO:007259440.015
positive regulation of nucleic acid templated transcriptionGO:1903508570.015
stem cell proliferationGO:007208940.015
positive regulation of response to stimulusGO:0048584800.015
positive regulation of transcription dna templatedGO:0045893570.015
circulatory system processGO:0003013870.015
regulation of organ growthGO:004662030.015
defense responseGO:0006952470.015
regulation of response to cytokine stimulusGO:006075930.015
negative regulation of signal transduction in absence of ligandGO:190109910.015
regulation of nucleoside metabolic processGO:000911820.015
developmental pigmentationGO:0048066480.015
developmental growthGO:00485891660.015
lipid biosynthetic processGO:0008610220.015
skeletal system morphogenesisGO:00487051020.015
cellular protein metabolic processGO:00442671290.015
positive regulation of nucleotide catabolic processGO:003081310.015
cellular response to xenobiotic stimulusGO:0071466350.015
acylglycerol homeostasisGO:005509020.015
protein secretionGO:000930610.015
metal ion transportGO:0030001580.015
behaviorGO:0007610740.015
positive regulation of response to external stimulusGO:003210390.015
cation transportGO:0006812810.015
cell migration involved in gastrulationGO:0042074790.015
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.015
angiogenesisGO:00015251580.014
positive regulation of cellular amine metabolic processGO:003324000.014
keratinocyte differentiationGO:003021600.014
lipid catabolic processGO:001604240.014
multicellular organism growthGO:003526440.014
secondary metabolic processGO:001974830.014
antimicrobial humoral responseGO:001973020.014
response to uvGO:000941130.014
positive regulation of multi organism processGO:004390230.014
positive regulation of gtp catabolic processGO:003312610.014
cellular divalent inorganic cation homeostasisGO:0072503130.014
regulation of transcription from rna polymerase ii promoterGO:00063571140.014
defense response to fungusGO:005083220.014
regulation of cellular ketone metabolic processGO:001056570.014
cellular chemical homeostasisGO:0055082170.014
sensory organ developmentGO:00074233930.014
lipid homeostasisGO:005508830.014
positive regulation of myeloid cell differentiationGO:004563920.014
bone mineralizationGO:003028290.014
regulation of cellular amine metabolic processGO:003323800.014
estrogen metabolic processGO:000821020.014
post embryonic morphogenesisGO:000988640.014
odontogenesis of dentin containing toothGO:004247510.014
positive regulation of production of molecular mediator of immune responseGO:000270210.013
phosphorus metabolic processGO:00067931090.013
cellular response to decreased oxygen levelsGO:003629410.013
single organism nuclear importGO:190259330.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.013
protein targeting to nucleusGO:004474430.013
protein complex disassemblyGO:004324110.013
adherens junction organizationGO:003433240.013
meiosis iGO:000712710.013
camera type eye morphogenesisGO:00485931080.013
cellular amino acid metabolic processGO:000652070.013
protein homooligomerizationGO:005126030.013
programmed cell deathGO:00125011190.013
multi organism cellular processGO:004476420.013
establishment of endothelial barrierGO:006102830.013
rna localizationGO:000640340.013
tissue remodelingGO:004877140.013
spermatid developmentGO:000728620.013
cellular homeostasisGO:0019725260.013
regulation of gtpase activityGO:004308720.013
positive regulation of protein polymerizationGO:003227320.013
signal transduction in absence of ligandGO:003803410.012
cellular response to organic substanceGO:00713101050.012
cellular response to oxygen levelsGO:007145310.012
calcium ion homeostasisGO:0055074190.012
regulation of reproductive processGO:200024140.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
monocyte differentiationGO:003022420.012
epidermis developmentGO:0008544480.012
positive regulation of metabolic processGO:00098931080.012
regulation of embryonic developmentGO:0045995470.012
ion homeostasisGO:0050801410.012
response to hexoseGO:000974630.012
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.012
regulation of cellular amino acid metabolic processGO:000652100.012
extracellular matrix organizationGO:0030198270.012
positive regulation of neuron deathGO:190121610.012
regulation of protein targetingGO:190353320.012
positive regulation of leukocyte mediated immunityGO:000270510.012
positive regulation of blood circulationGO:190352420.012
regulation of dna templated transcription in response to stressGO:004362000.012
endocrine hormone secretionGO:006098620.012
histone h3 k4 methylationGO:005156820.012
thermosensory behaviorGO:004004010.012
regulation of cell shapeGO:000836010.012
positive regulation of molecular functionGO:0044093330.012
negative regulation of nucleobase containing compound metabolic processGO:0045934590.012
regulation of systemic arterial blood pressureGO:000307310.012
calcium ion importGO:007050940.012
regenerationGO:0031099910.012
extracellular structure organizationGO:0043062270.012
regulation of cell differentiationGO:00455951420.012
adherens junction maintenanceGO:003433420.012
reactive oxygen species biosynthetic processGO:190340910.012
response to biotic stimulusGO:0009607970.012
positive regulation of defense response to virus by hostGO:000223000.012
apoptotic process involved in developmentGO:190274220.012
regulation of multicellular organismal developmentGO:20000262230.012
negative regulation of protein localization to nucleusGO:190018120.012
appendage developmentGO:0048736800.012
positive regulation of rna biosynthetic processGO:1902680570.012
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.012
regulation of cellular protein catabolic processGO:190336210.011
negative regulation of defense responseGO:003134820.011
regulation of muscle contractionGO:000693730.011
oxoacid metabolic processGO:0043436310.011
negative regulation of multi organism processGO:004390130.011
developmental programmed cell deathGO:001062340.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
cytokine metabolic processGO:004210710.011
dna templated transcription elongationGO:000635430.011
protein importGO:001703830.011
negative regulation of kinase activityGO:003367340.011
germ line stem cell maintenanceGO:003071820.011
multi organism processGO:00517041340.011
mesenchyme developmentGO:00604851270.011
single fertilizationGO:000733830.011
energy reserve metabolic processGO:000611220.011
brain developmentGO:00074202930.011
alcohol biosynthetic processGO:004616520.011
regulation of ion transmembrane transporter activityGO:003241220.011
heart processGO:0003015710.011
peptide transportGO:001583310.011
regulation of glycoprotein biosynthetic processGO:001055930.011
macromolecule glycosylationGO:004341390.011
regulation of nucleotide catabolic processGO:003081120.011
multicellular organismal metabolic processGO:004423620.011
regulation of cytokine mediated signaling pathwayGO:000195930.011
rna 3 end processingGO:003112320.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
regulation of purine nucleotide catabolic processGO:003312120.011
phosphatidylinositol mediated signalingGO:004801520.011
spermatid differentiationGO:004851520.011
wound healingGO:0042060900.011
cellular response to steroid hormone stimulusGO:0071383310.011
protein dephosphorylationGO:000647030.011
regulation of cardiac muscle tissue developmentGO:005502410.011
meiotic nuclear divisionGO:000712640.011
cartilage developmentGO:0051216960.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
positive regulation of cell adhesionGO:004578510.011
neuroblast differentiationGO:001401610.011
cation transmembrane transportGO:0098655650.011
regulation of heart growthGO:006042020.011
myeloid leukocyte differentiationGO:0002573150.011
regulation of cell migration involved in sprouting angiogenesisGO:009004930.011
negative regulation of apoptotic processGO:0043066550.011
regulation of cysteine type endopeptidase activityGO:2000116210.011
organic anion transportGO:0015711150.011
sphingolipid metabolic processGO:000666590.011
t cell mediated immunityGO:000245610.010
regulation of gtp catabolic processGO:003312420.010
response to oxygen containing compoundGO:1901700550.010
endothelium developmentGO:0003158250.010
endodermal cell fate determinationGO:000749320.010
regulation of innate immune responseGO:0045088110.010
cellular ion homeostasisGO:0006873170.010
fertilizationGO:000956630.010
cell projection organizationGO:00300302840.010
neuron neuron synaptic transmissionGO:000727010.010
positive regulation of nucleobase containing compound metabolic processGO:0045935690.010
response to hypoxiaGO:0001666250.010
blood circulationGO:0008015870.010
positive regulation of cellular biosynthetic processGO:0031328680.010
regulation of dna replicationGO:000627530.010
response to transition metal nanoparticleGO:1990267280.010
convergent extension involved in gastrulationGO:0060027710.010
erythrocyte differentiationGO:0030218540.010

LOC100004946 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.123
cancerDOID:16200.070
organ system cancerDOID:005068600.070
disease of cellular proliferationDOID:1456600.070
muscular diseaseDOID:008000000.045
musculoskeletal system diseaseDOID:1700.045
muscle tissue diseaseDOID:6600.045
myopathyDOID:42300.045
cardiovascular system diseaseDOID:128700.026
connective tissue diseaseDOID:6500.012
disease of metabolismDOID:001466700.011
immune system diseaseDOID:291400.010