Danio rerio

11 known processes

cx41.8

connexin 41.8

cx41.8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pigmentationGO:0043473850.734
cellular pigmentationGO:0033059300.659
pigment granule localizationGO:0051875250.363
pigment cell differentiationGO:0050931380.292
developmental pigmentationGO:0048066480.288
melanocyte differentiationGO:0030318260.209
transmembrane transportGO:00550851200.206
larval developmentGO:000216420.202
establishment of pigment granule localizationGO:0051905220.151
biosynthetic processGO:00090582940.144
negative regulation of cellular processGO:00485232830.141
cellular biosynthetic processGO:00442492860.129
rna metabolic processGO:00160702190.119
camera type eye developmentGO:00430102220.118
retina development in camera type eyeGO:00600411460.118
sensory organ developmentGO:00074233930.112
Zebrafish
cognitionGO:005089010.107
cellular aromatic compound metabolic processGO:00067252950.106
tissue remodelingGO:004877140.102
Mouse
regulation of synaptic growth at neuromuscular junctionGO:000858210.094
regulation of primary metabolic processGO:00800903110.093
monovalent inorganic cation transportGO:0015672420.086
organic substance biosynthetic processGO:19015762890.085
establishment of organelle localizationGO:0051656450.084
ion transportGO:00068111140.081
Zebrafish Mouse
vesicle localizationGO:0051648270.077
immune system developmentGO:00025201910.076
Zebrafish
cellular nitrogen compound metabolic processGO:00346412900.076
neuroepithelial cell differentiationGO:0060563260.075
skeletal system developmentGO:00015011810.075
Zebrafish Mouse
nitrogen compound metabolic processGO:00068073190.074
ribonucleoside monophosphate catabolic processGO:000915840.070
chemosensory behaviorGO:000763510.069
organic cyclic compound metabolic processGO:19013603010.068
nucleobase containing compound metabolic processGO:00061392740.068
nucleic acid metabolic processGO:00903042440.067
regulation of nucleobase containing compound metabolic processGO:00192192500.066
organic cyclic compound biosynthetic processGO:19013622230.066
metal ion transportGO:0030001580.063
pigment granule aggregation in cell centerGO:005187780.062
system processGO:00030081850.061
Zebrafish Mouse
cell surface receptor signaling pathwayGO:00071663250.059
cellular amine metabolic processGO:004410620.059
inorganic ion transmembrane transportGO:0098660570.058
cellular macromolecule metabolic processGO:00442603910.058
organelle localizationGO:0051640490.058
regulation of rna biosynthetic processGO:20011412130.057
regulation of macromolecule metabolic processGO:00602553170.056
regulation of macromolecule biosynthetic processGO:00105562250.056
agingGO:000756820.056
establishment of localizationGO:00512342440.054
regulation of cell shapeGO:000836010.052
eye developmentGO:00016542770.050
specification of symmetryGO:00097992040.049
regulation of synapse organizationGO:005080730.049
heterocycle metabolic processGO:00464832900.048
macromolecule biosynthetic processGO:00090592270.048
nucleoside monophosphate catabolic processGO:000912540.047
regulation of cellular biosynthetic processGO:00313262450.047
determination of bilateral symmetryGO:00098552040.046
regulation of cellular macromolecule biosynthetic processGO:20001122220.046
negative regulation of biological processGO:00485193040.046
inorganic cation transmembrane transportGO:0098662500.045
establishment of vesicle localizationGO:0051650240.045
regulation of biosynthetic processGO:00098892500.045
transcription dna templatedGO:00063511810.043
sensory organ morphogenesisGO:00905962000.043
regulation of metabolic processGO:00192223590.042
cation transmembrane transportGO:0098655650.042
regionalizationGO:00030022740.041
epithelial cell differentiationGO:00308551160.040
nucleic acid templated transcriptionGO:00976591810.040
cellular potassium ion transportGO:0071804100.039
purine nucleoside monophosphate catabolic processGO:000912840.039
phenol containing compound biosynthetic processGO:004618940.039
digestive system developmentGO:00551232890.039
regulation of rna metabolic processGO:00512522240.038
chordate embryonic developmentGO:00430092710.037
Zebrafish
nucleobase containing compound biosynthetic processGO:00346542050.037
single organism transportGO:00447652060.037
morphogenesis of an epitheliumGO:00020093330.036
maintenance of locationGO:005123540.036
regulation of synapse assemblyGO:005196330.035
multicellular organism growthGO:003526440.035
digestive tract developmentGO:00485652650.034
potassium ion transportGO:0006813100.034
gland developmentGO:00487321430.034
muscle organ developmentGO:00075171010.034
embryonic organ developmentGO:00485683810.034
Zebrafish Mouse
adult behaviorGO:003053420.033
positive regulation of biological processGO:00485182530.033
gene expressionGO:00104672520.032
regulation of cellular amine metabolic processGO:003323800.032
organelle fusionGO:004828430.032
wnt signaling pathwayGO:0016055800.031
determination of left right symmetryGO:00073681790.031
pigment granule organizationGO:004875340.031
signal transductionGO:00071654550.031
stem cell maintenanceGO:001982740.030
organism emergence from protective structureGO:007168440.030
stem cell proliferationGO:007208940.030
heart loopingGO:0001947940.029
positive regulation of transcription dna templatedGO:0045893570.029
synaptic growth at neuromuscular junctionGO:005112420.029
cation transportGO:0006812810.029
organonitrogen compound metabolic processGO:1901564740.028
regulation of gene expressionGO:00104682650.028
amine metabolic processGO:000930820.028
heterocycle biosynthetic processGO:00181302150.028
secondary metabolic processGO:001974830.027
head developmentGO:00603223030.027
mesenchyme developmentGO:00604851270.027
atp catabolic processGO:000620040.027
cellular amino acid metabolic processGO:000652070.027
cell fate commitmentGO:0045165990.026
compound eye developmentGO:004874920.026
oxoacid metabolic processGO:0043436310.026
immune system processGO:00023762410.026
Zebrafish
regulation of synaptic plasticityGO:004816710.025
regulation of signal transductionGO:00099662250.025
regulation of transcription from rna polymerase ii promoterGO:00063571140.025
cellular localizationGO:0051641970.025
Mouse
eye morphogenesisGO:00485921440.025
small molecule metabolic processGO:0044281770.025
positive regulation of nitrogen compound metabolic processGO:0051173690.024
gtp metabolic processGO:004603940.024
carboxylic acid metabolic processGO:0019752220.024
alcohol biosynthetic processGO:004616520.024
embryonic skeletal system developmentGO:0048706970.024
Zebrafish
positive regulation of cellular catabolic processGO:003133130.024
transportGO:00068102200.024
hormone transportGO:000991420.023
single organism metabolic processGO:00447102170.023
melanin metabolic processGO:000658220.023
regulation of cytokine productionGO:000181730.023
tube morphogenesisGO:00352393490.023
cellular nitrogen compound biosynthetic processGO:00442712180.022
regulation of nucleic acid templated transcriptionGO:19035062130.022
purine ribonucleoside monophosphate catabolic processGO:000916940.022
digestive tract morphogenesisGO:00485462310.022
myeloid cell differentiationGO:0030099860.022
protein stabilizationGO:005082120.022
multicellular organismal response to stressGO:003355520.022
positive regulation of cellular component biogenesisGO:004408930.022
multicellular organismal signalingGO:0035637220.022
Mouse
negative regulation of metabolic processGO:0009892860.022
embryonic skeletal system morphogenesisGO:0048704930.022
Zebrafish
phagocytosisGO:000690930.022
positive regulation of wound healingGO:009030310.021
transcription from rna polymerase ii promoterGO:0006366800.021
single organism localizationGO:19025782250.021
phototransductionGO:000760220.021
negative regulation of protein kinase activityGO:000646940.021
regulation of multicellular organismal developmentGO:20000262230.020
neurotransmitter secretionGO:000726920.020
rna biosynthetic processGO:00327741810.020
positive regulation of catabolic processGO:000989640.020
muscle structure developmentGO:00610611960.020
Zebrafish
dorsal ventral pattern formationGO:00099531250.020
lipid storageGO:001991510.020
positive regulation of epithelial cell proliferationGO:005067910.020
response to drugGO:004249330.020
cellular response to extracellular stimulusGO:003166820.020
apoptotic processGO:00069151160.020
embryonic cranial skeleton morphogenesisGO:0048701900.020
phosphorylationGO:0016310690.020
regulation of multicellular organism growthGO:004001440.020
gtp catabolic processGO:000618420.020
embryonic organ morphogenesisGO:00485622740.019
Zebrafish
regulation of cell communicationGO:00106462320.019
cellular component assemblyGO:00226071700.019
Zebrafish
cartilage developmentGO:0051216960.019
negative regulation of protein phosphorylationGO:000193340.019
response to hexoseGO:000974630.019
diterpenoid metabolic processGO:0016101150.019
regulation of signalingGO:00230512350.019
regulation of stem cell proliferationGO:007209120.019
regulation of protein modification by small protein conjugation or removalGO:190332030.019
sensory perception of chemical stimulusGO:000760630.019
alpha amino acid metabolic processGO:190160530.019
positive regulation of cellular processGO:00485222010.019
cellular macromolecule biosynthetic processGO:00346452240.019
g protein coupled receptor signaling pathwayGO:0007186740.019
skeletal muscle tissue developmentGO:0007519670.019
fluid transportGO:0042044170.019
cellular protein metabolic processGO:00442671290.019
negative regulation of programmed cell deathGO:0043069580.019
determination of heart left right asymmetryGO:00613711170.019
positive regulation of cellular biosynthetic processGO:0031328680.018
positive regulation of cell cycleGO:004578730.018
hatchingGO:003518840.018
regulation of dendrite developmentGO:005077330.018
regulation of nucleotide catabolic processGO:003081120.018
hormone secretionGO:004687920.018
positive regulation of transportGO:005105020.018
neuron differentiationGO:00301823530.018
cellular response to nutrient levelsGO:003166920.018
regulation of cell activationGO:005086510.018
generation of neuronsGO:00486993850.018
regulation of protein catabolic processGO:004217610.018
embryonic heart tube morphogenesisGO:00031431080.018
regulation of cellular amino acid metabolic processGO:000652100.018
regulation of dendrite morphogenesisGO:004881430.018
melanosome localizationGO:0032400210.018
catechol containing compound metabolic processGO:000971220.018
regulation of cellular metabolic processGO:00313233200.018
catecholamine metabolic processGO:000658420.018
signal transduction in absence of ligandGO:003803410.017
macromolecular complex assemblyGO:0065003350.017
cellular response to external stimulusGO:007149620.017
muscle tissue developmentGO:00605371100.017
Zebrafish Mouse
cell deathGO:00082191210.017
b cell activationGO:004211320.017
glial cell migrationGO:000834730.017
heart developmentGO:00075073130.017
Zebrafish Mouse
regulation of syncytium formation by plasma membrane fusionGO:006014220.017
regulation of purine nucleotide catabolic processGO:003312120.017
programmed cell deathGO:00125011190.017
response to other organismGO:0051707970.017
regulation of nucleoside metabolic processGO:000911820.017
cell morphogenesisGO:00009022890.017
regulation of epithelial cell proliferationGO:005067830.017
regulation of rho protein signal transductionGO:003502320.017
potassium ion transmembrane transportGO:0071805100.017
response to topologically incorrect proteinGO:003596620.016
peptidyl serine modificationGO:001820920.016
guanosine containing compound metabolic processGO:190106840.016
oxidation reduction processGO:0055114410.016
positive regulation of rna metabolic processGO:0051254590.016
deathGO:00162651210.016
positive regulation of nucleotide catabolic processGO:003081310.016
neural crest cell developmentGO:0014032620.016
cellular aldehyde metabolic processGO:000608140.016
cellular component assembly involved in morphogenesisGO:00109271070.016
Zebrafish
regenerationGO:0031099910.016
Zebrafish
regulation of nitrogen compound metabolic processGO:00511712510.016
mesenchymal cell developmentGO:0014031780.016
neuron neuron synaptic transmissionGO:000727010.016
regulation of cell differentiationGO:00455951420.016
macromolecular complex disassemblyGO:003298410.016
membrane fusionGO:006102520.016
regulation of developmental pigmentationGO:004807060.015
pathway restricted smad protein phosphorylationGO:006038910.015
positive regulation of secretionGO:005104710.015
response to external stimulusGO:00096052640.015
embryonic viscerocranium morphogenesisGO:0048703520.015
guanosine containing compound catabolic processGO:190106920.015
autophagyGO:000691440.015
cell morphogenesis involved in differentiationGO:00009041950.015
positive regulation of rna biosynthetic processGO:1902680570.015
dopamine biosynthetic processGO:004241620.015
neuroblast proliferationGO:000740520.015
germ line stem cell maintenanceGO:003071820.015
establishment of synaptic vesicle localizationGO:009748010.015
golgi vesicle transportGO:004819330.015
positive regulation of nucleoside metabolic processGO:004597910.015
positive regulation of map kinase activityGO:004340630.015
regulation of reproductive processGO:200024140.015
response to organic substanceGO:00100331530.014
epithelial tube morphogenesisGO:00605621480.014
cardiac atrium developmentGO:000323040.014
Mouse
establishment of localization in cellGO:0051649770.014
Mouse
cellular response to topologically incorrect proteinGO:003596720.014
peptide transportGO:001583310.014
sodium ion transportGO:0006814240.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
positive regulation of macromolecule biosynthetic processGO:0010557590.014
nuclear exportGO:005116810.014
protein polymerizationGO:005125840.014
regulation of metal ion transportGO:001095940.014
melanocyte migrationGO:009732440.014
establishment of protein localization to plasma membraneGO:009000210.014
peptidyl serine phosphorylationGO:001810510.014
viral processGO:001603210.014
camera type eye morphogenesisGO:00485931080.014
single organism membrane fusionGO:004480120.014
protein acetylationGO:000647320.014
retinal rod cell developmentGO:004654840.014
neuromuscular synaptic transmissionGO:000727420.014
embryo development ending in birth or egg hatchingGO:00097922710.014
Zebrafish
regulation of immune system processGO:0002682340.014
epithelial cell migrationGO:0010631250.014
cellular response to starvationGO:000926710.014
protein homooligomerizationGO:005126030.013
multi organism cellular processGO:004476420.013
regulation of hormone secretionGO:004688320.013
cilium morphogenesisGO:0060271850.013
regulation of transcription dna templatedGO:00063552130.013
interspecies interaction between organismsGO:004441940.013
neurotransmitter transportGO:000683620.013
positive regulation of gtpase activityGO:004354710.013
response to monosaccharideGO:003428430.013
regulation of ion transmembrane transporter activityGO:003241220.013
regulation of organelle assemblyGO:190211540.013
smooth muscle contractionGO:000693920.013
regulation of tube sizeGO:003515020.013
Mouse
bone remodelingGO:004684920.013
regulation of gtpase activityGO:004308720.013
regulation of protein transportGO:005122330.013
Mouse
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
growthGO:00400071740.013
Zebrafish
detection of stimulusGO:0051606290.013
myeloid leukocyte differentiationGO:0002573150.013
negative regulation of macromolecule metabolic processGO:0010605760.013
modification dependent macromolecule catabolic processGO:004363230.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
Zebrafish
regulation of bindingGO:005109830.013
regulation of protein complex assemblyGO:004325430.013
cell migrationGO:00164772370.013
negative regulation of biosynthetic processGO:0009890550.013
appendage developmentGO:0048736800.013
Zebrafish Mouse
regulation of developmental processGO:00507932470.013
macromolecule modificationGO:00434121110.013
extrinsic apoptotic signaling pathwayGO:009719130.013
internal protein amino acid acetylationGO:000647520.013
protein localization to plasma membraneGO:007265910.013
protein complex disassemblyGO:004324110.013
mesenchymal cell differentiationGO:0048762870.013
protein metabolic processGO:00195381830.013
nucleic acid transportGO:005065720.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
negative regulation of synapse assemblyGO:005196420.013
aromatic compound biosynthetic processGO:00194382170.013
positive regulation of gtp catabolic processGO:003312610.013
oocyte maturationGO:000155640.013
urogenital system developmentGO:0001655970.013
positive regulation of secretion by cellGO:190353210.013
activation of mapk activityGO:000018730.013
endoplasmic reticulum unfolded protein responseGO:003096820.013
epithelium migrationGO:0090132250.012
specification of organ identityGO:001009220.012
response to ketoneGO:190165410.012
periodic partitioningGO:000736510.012
central nervous system developmentGO:00074173870.012
single organism organelle organizationGO:19025891990.012
Zebrafish
cellular response to organic cyclic compoundGO:0071407380.012
positive regulation of synapse assemblyGO:005196510.012
cellular component disassemblyGO:002241110.012
production of molecular mediator of immune responseGO:000244020.012
determination of dorsal ventral asymmetryGO:0048262340.012
anterior lateral line nerve developmentGO:004890940.012
neurological system processGO:0050877620.012
Zebrafish
regulation of calcium ion transportGO:005192420.012
cellular protein modification processGO:00064641000.012
regulation of cellular ketone metabolic processGO:001056570.012
mechanosensory behaviorGO:000763820.012
response to vitaminGO:003327330.012
leukocyte proliferationGO:007066110.012
exocytosisGO:000688710.012
negative regulation of cellular catabolic processGO:003133030.012
regulation of cell deathGO:00109411030.012
regulation of dna recombinationGO:000001820.012
organelle organizationGO:00069962270.012
Zebrafish
skeletal system morphogenesisGO:00487051020.012
Zebrafish
calcium ion homeostasisGO:0055074190.012
water transportGO:0006833150.012
hepaticobiliary system developmentGO:0061008980.012
organic acid metabolic processGO:0006082310.012
retina morphogenesis in camera type eyeGO:0060042790.012
peptidyl threonine phosphorylationGO:001810710.012
ear developmentGO:00435831270.012
Zebrafish
phosphate containing compound metabolic processGO:00067961080.012
protein dephosphorylationGO:000647030.012
negative regulation of oocyte developmentGO:006028320.012
myofibril assemblyGO:0030239480.012
Zebrafish
proteasomal protein catabolic processGO:001049820.012
columnar cuboidal epithelial cell differentiationGO:0002065380.012
negative regulation of cellular metabolic processGO:0031324770.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.012
multi organism processGO:00517041340.012
positive regulation of cellular amine metabolic processGO:003324000.012
response to glucoseGO:000974930.012
regulation of cytoplasmic transportGO:190364940.012
regulation of organ growthGO:004662030.012
developmental programmed cell deathGO:001062340.012
cellular response to light stimulusGO:007148240.012
microtubule based processGO:0007017600.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
notochord developmentGO:0030903540.012
organelle assemblyGO:00709251100.012
Zebrafish
internal peptidyl lysine acetylationGO:001839320.012
negative regulation of defense responseGO:003134820.011
lateral inhibitionGO:004633110.011
fin developmentGO:0033333770.011
Zebrafish
response to external biotic stimulusGO:0043207970.011
regulation of programmed cell deathGO:00430671010.011
cellular response to organic substanceGO:00713101050.011
negative regulation of catabolic processGO:000989530.011
rna transportGO:005065820.011
regulation of apoptotic processGO:0042981980.011
long chain fatty acid metabolic processGO:000167610.011
protein complex subunit organizationGO:0071822460.011
positive regulation of heart contractionGO:004582320.011
response to carbohydrateGO:000974330.011
sensory perception of painGO:001923310.011
cellular amide metabolic processGO:004360340.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
brain developmentGO:00074202930.011
response to nutrientGO:000758430.011
protein complex assemblyGO:0006461300.011
centrosome cycleGO:000709810.011
er nucleus signaling pathwayGO:000698420.011
positive regulation of gene expressionGO:0010628710.011
detection of chemical stimulusGO:000959340.011
inner ear developmentGO:00488391260.011
Zebrafish
symbiosis encompassing mutualism through parasitismGO:004440340.011
negative regulation of signalingGO:0023057960.011
taxisGO:00423301090.011
cellular response to unfolded proteinGO:003462020.011
organonitrogen compound biosynthetic processGO:1901566470.011
sequestering of metal ionGO:005123830.011
developmental growthGO:00485891660.011
Zebrafish
positive regulation of notch signaling pathwayGO:004574730.011
stem cell differentiationGO:00488631170.011
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.011
negative regulation of macromolecule biosynthetic processGO:0010558480.011
actin filament based movementGO:003004810.011
response to chemicalGO:00422213200.011
i kappab kinase nf kappab signalingGO:000724940.011
protein complex biogenesisGO:0070271300.011
melanin biosynthetic processGO:004243810.011
regulation of transporter activityGO:003240920.011
establishment of protein localization to organelleGO:007259440.011
nucleocytoplasmic transportGO:000691340.010
cellular response to radiationGO:007147840.010
regulation of response to stimulusGO:00485832690.010
superoxide metabolic processGO:000680120.010
leukocyte homeostasisGO:000177620.010
regulation of phosphate metabolic processGO:0019220430.010
cell cycle g1 s phase transitionGO:004484310.010
muscle cell differentiationGO:00426921390.010
Zebrafish
tyrosine phosphorylation of stat proteinGO:000726010.010
regulation of neuronal synaptic plasticityGO:004816810.010
regulation of muscle contractionGO:000693730.010
Mouse
vesicle organizationGO:001605060.010
cellular component biogenesisGO:00440851780.010
Zebrafish
positive regulation of cytokine productionGO:000181920.010
positive regulation of macromolecule metabolic processGO:0010604930.010
phagocytosis engulfmentGO:000691110.010
neuromuscular process controlling balanceGO:005088530.010
negative regulation of cellular biosynthetic processGO:0031327550.010
trabecula morphogenesisGO:006138320.010
determination of ventral identityGO:0048264210.010
cellular response to dsrnaGO:007135910.010
olfactory placode developmentGO:0071698120.010
endosomal transportGO:001619720.010
positive regulation of translationGO:004572710.010
cell morphogenesis involved in neuron differentiationGO:00486671630.010
cellular protein complex disassemblyGO:004362410.010
positive regulation of nucleobase containing compound metabolic processGO:0045935690.010
synaptic vesicle transportGO:004848910.010

cx41.8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.014
musculoskeletal system diseaseDOID:1700.014
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.013
cancerDOID:16200.013
nervous system diseaseDOID:86300.012
gastrointestinal system cancerDOID:311900.011