IMP: Integrative Multi-species Prediction

Danio rerio

30 known processes

ctnnb1

catenin (cadherin-associated protein), beta 1

(Aliases: ctnnb,wu:fb73e10,wu:fk25h01,id:ibd2058,wu:fi81c06)

Ensembl: ENSDARG00000014571
Entrez: 30265
ZFIN: ZDB-GENE-980526-362
UniProtKB: Q7ZU14

Process Predictions
Disease Predictions

ctnnb1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
biosynthetic process	GO:0009058	294	0.856	Human Mouse Worm Fly
cell morphogenesis involved in differentiation	GO:0000904	195	0.765	Human Mouse
larval development	GO:0002164	2	0.694	Worm Fly
organic substance biosynthetic process	GO:1901576	289	0.664	Human Mouse Worm Fly
morphogenesis of an epithelium	GO:0002009	333	0.646
macromolecule glycosylation	GO:0043413	9	0.643
cellular component movement	GO:0006928	335	0.622	Mouse Worm
positive regulation of biological process	GO:0048518	253	0.593	Human Mouse Worm Fly
positive regulation of cellular process	GO:0048522	201	0.535	Human Mouse Worm Fly
regulation of cellular metabolic process	GO:0031323	320	0.535	Human Mouse Worm Fly
ameboidal type cell migration	GO:0001667	143	0.521	Worm
protein glycosylation	GO:0006486	9	0.519
regulation of multicellular organismal process	GO:0051239	277	0.518	Human Zebrafish Mouse Worm Fly
heterocycle biosynthetic process	GO:0018130	215	0.517	Human Mouse Worm Fly
cell morphogenesis	GO:0000902	289	0.514	Human Mouse Fly
organelle organization	GO:0006996	227	0.514	Human Mouse Worm
epithelial cell morphogenesis	GO:0003382	2	0.512	Mouse
nitrogen compound metabolic process	GO:0006807	319	0.495	Human Mouse Worm Fly
embryonic heart tube development	GO:0035050	133	0.485	Mouse
axon development	GO:0061564	166	0.467
regulation of primary metabolic process	GO:0080090	311	0.457	Human Mouse Worm Fly
regulation of metabolic process	GO:0019222	359	0.453	Human Mouse Worm Fly
response to wounding	GO:0009611	116	0.451
glycoprotein biosynthetic process	GO:0009101	21	0.432	Human
sensory organ development	GO:0007423	393	0.430	Mouse Fly
cell projection morphogenesis	GO:0048858	244	0.418
sexual reproduction	GO:0019953	36	0.411	Mouse Worm Fly
cellular component morphogenesis	GO:0032989	336	0.392	Human Mouse Fly
heart development	GO:0007507	313	0.380	Zebrafish Mouse Fly
single organism localization	GO:1902578	225	0.379	Human Mouse Fly
regulation of mrna splicing via spliceosome	GO:0048024	3	0.370
localization of cell	GO:0051674	244	0.368	Mouse Worm
positive regulation of catabolic process	GO:0009896	4	0.358
regulation of mrna processing	GO:0050684	3	0.357
cellular protein metabolic process	GO:0044267	129	0.338	Human Worm
cell cycle	GO:0007049	93	0.332	Human Mouse Worm
dorsal ventral pattern formation	GO:0009953	125	0.330
neuron development	GO:0048666	262	0.312
regulation of organelle organization	GO:0033043	29	0.306	Human Mouse Worm
axonogenesis	GO:0007409	152	0.305
regulation of response to stimulus	GO:0048583	269	0.304	Zebrafish Mouse
cellular biosynthetic process	GO:0044249	286	0.294	Human Mouse Worm Fly
determination of left right symmetry	GO:0007368	179	0.291
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules	GO:0016339	2	0.291
axon guidance	GO:0007411	86	0.284
positive regulation of stress activated protein kinase signaling cascade	GO:0070304	3	0.274
cell motility	GO:0048870	244	0.274	Mouse Worm
macromolecule biosynthetic process	GO:0009059	227	0.272	Human Mouse Worm Fly
carbohydrate derivative biosynthetic process	GO:1901137	43	0.270	Human
gene expression	GO:0010467	252	0.265	Human Mouse Worm Fly
glycoprotein metabolic process	GO:0009100	23	0.264	Human
cell cycle process	GO:0022402	53	0.262	Human Mouse Worm
regulation of macromolecule biosynthetic process	GO:0010556	225	0.261	Human Mouse Worm Fly
aromatic compound biosynthetic process	GO:0019438	217	0.253	Human Mouse Worm Fly
nucleobase containing compound biosynthetic process	GO:0034654	205	0.244	Human Mouse Worm Fly
cellular protein catabolic process	GO:0044257	4	0.242
nuclear import	GO:0051170	3	0.236
anterior posterior pattern specification	GO:0009952	152	0.235	Mouse
protein import	GO:0017038	3	0.234
response to chemical	GO:0042221	320	0.230	Human Mouse
cellular macromolecule biosynthetic process	GO:0034645	224	0.228	Human Mouse Worm Fly
protein targeting to nucleus	GO:0044744	3	0.228
cellular component biogenesis	GO:0044085	178	0.227	Human Fly
neuron projection morphogenesis	GO:0048812	161	0.227
organic cyclic compound biosynthetic process	GO:1901362	223	0.223	Human Mouse Worm Fly
regulation of protein metabolic process	GO:0051246	56	0.222	Human Worm
positive regulation of cellular catabolic process	GO:0031331	3	0.222
regulation of rna metabolic process	GO:0051252	224	0.218	Human Mouse Worm Fly
positive regulation of cellular metabolic process	GO:0031325	94	0.217	Human Mouse Worm Fly
positive regulation of notch signaling pathway	GO:0045747	3	0.210
medial fin development	GO:0033338	16	0.205
response to stress	GO:0006950	263	0.204
somite development	GO:0061053	96	0.203
negative regulation of cellular metabolic process	GO:0031324	77	0.199	Human Mouse
positive regulation of stress activated mapk cascade	GO:0032874	3	0.195
regulation of developmental process	GO:0050793	247	0.195	Human Zebrafish Mouse Worm Fly
positive regulation of metabolic process	GO:0009893	108	0.192	Human Mouse Worm Fly
mitotic cell cycle	GO:0000278	64	0.187	Mouse Worm
dorsal convergence	GO:0060030	14	0.185
regulation of signaling	GO:0023051	235	0.180	Zebrafish Mouse Fly
regulation of cellular component organization	GO:0051128	86	0.178	Human Mouse Worm Fly
positive regulation of jnk cascade	GO:0046330	3	0.177
regulation of biological quality	GO:0065008	263	0.175	Mouse Fly
adherens junction maintenance	GO:0034334	2	0.174
regulation of establishment of protein localization	GO:0070201	4	0.174
multi organism process	GO:0051704	134	0.171	Mouse Worm Fly
glycosylation	GO:0070085	11	0.171
mesenchyme development	GO:0060485	127	0.166	Human Mouse
stem cell differentiation	GO:0048863	117	0.161	Human Fly
regulation of apoptotic process	GO:0042981	98	0.161	Human Mouse
single organism nuclear import	GO:1902593	3	0.160
carbohydrate derivative metabolic process	GO:1901135	61	0.160	Human
specification of axis polarity	GO:0065001	4	0.158	Worm
eye development	GO:0001654	277	0.156	Mouse Fly
cytoskeleton organization	GO:0007010	96	0.156	Human Worm
skeletal system development	GO:0001501	181	0.156	Mouse
regulation of rna biosynthetic process	GO:2001141	213	0.154	Human Mouse Worm Fly
reproductive process	GO:0022414	40	0.154	Mouse Worm Fly
regulation of protein binding	GO:0043393	3	0.154
regulation of cell morphogenesis	GO:0022604	42	0.151	Human Fly
regulation of macromolecule metabolic process	GO:0060255	317	0.151	Human Mouse Worm Fly
germ line stem cell maintenance	GO:0030718	2	0.151
nuclear division	GO:0000280	23	0.150
establishment of protein localization to organelle	GO:0072594	4	0.149
single organism metabolic process	GO:0044710	217	0.149	Human Mouse
cell part morphogenesis	GO:0032990	246	0.148
cartilage development	GO:0051216	96	0.147	Mouse
embryo development ending in birth or egg hatching	GO:0009792	271	0.146	Mouse Worm Fly
protein import into nucleus	GO:0006606	3	0.146
cell recognition	GO:0008037	19	0.146
multicellular organism growth	GO:0035264	4	0.141
meiotic nuclear division	GO:0007126	4	0.138
cell death	GO:0008219	121	0.137	Human Mouse Fly
stem cell development	GO:0048864	82	0.137	Human Fly
stem cell maintenance	GO:0019827	4	0.135	Fly
modification dependent macromolecule catabolic process	GO:0043632	3	0.129
maintenance of location	GO:0051235	4	0.125
positive regulation of jun kinase activity	GO:0043507	2	0.125
cell surface receptor signaling pathway	GO:0007166	325	0.125	Human Zebrafish Mouse Worm Fly
nucleic acid metabolic process	GO:0090304	244	0.124	Human Mouse Worm Fly
axonal fasciculation	GO:0007413	11	0.124
regulation of epithelial cell proliferation	GO:0050678	3	0.123	Mouse
phagocytosis	GO:0006909	3	0.123
positive regulation of macromolecule metabolic process	GO:0010604	93	0.118	Human Mouse Worm Fly
spermatid differentiation	GO:0048515	2	0.116
skeletal system morphogenesis	GO:0048705	102	0.115	Mouse
regulation of protein catabolic process	GO:0042176	1	0.115
cell morphogenesis involved in neuron differentiation	GO:0048667	163	0.114
generation of neurons	GO:0048699	385	0.114	Mouse Fly
male meiosis	GO:0007140	2	0.113
segmentation	GO:0035282	97	0.111
regulation of cellular biosynthetic process	GO:0031326	245	0.109	Human Mouse Worm Fly
regulation of nervous system development	GO:0051960	90	0.109	Mouse
cellular localization	GO:0051641	97	0.108	Human Mouse Fly
mesenchymal cell development	GO:0014031	78	0.107	Human
optic placode formation	GO:0001743	4	0.107
ubiquitin dependent protein catabolic process	GO:0006511	3	0.107
rna metabolic process	GO:0016070	219	0.105	Human Mouse Worm Fly
single organism organelle organization	GO:1902589	199	0.105	Human Mouse Worm
convergent extension	GO:0060026	118	0.105
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	2	0.103
negative regulation of signaling	GO:0023057	96	0.102	Zebrafish Mouse Fly
aging	GO:0007568	2	0.099
adherens junction organization	GO:0034332	4	0.098	Human Mouse Fly
regulation of multicellular organismal development	GO:2000026	223	0.098	Human Zebrafish Mouse Worm Fly
response to organic substance	GO:0010033	153	0.098	Human Mouse
regulation of multicellular organism growth	GO:0040014	4	0.097
nucleocytoplasmic transport	GO:0006913	4	0.097
chemotaxis	GO:0006935	104	0.096
regulation of transcription from rna polymerase ii promoter	GO:0006357	114	0.095	Human Mouse Worm Fly
camera type eye morphogenesis	GO:0048593	108	0.094	Mouse
regulation of transcription dna templated	GO:0006355	213	0.093	Human Mouse Worm Fly
negative regulation of programmed cell death	GO:0043069	58	0.093	Human Mouse
regulation of cellular response to growth factor stimulus	GO:0090287	35	0.093	Mouse
nucleic acid templated transcription	GO:0097659	181	0.092	Human Mouse Worm Fly
rho protein signal transduction	GO:0007266	5	0.091
tube morphogenesis	GO:0035239	349	0.091	Human Mouse Worm Fly
regulation of stem cell proliferation	GO:0072091	2	0.091	Mouse
neuron projection development	GO:0031175	180	0.090
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	22	0.090	Human Mouse Worm Fly
cell fate commitment	GO:0045165	99	0.089	Mouse Worm Fly
cell migration	GO:0016477	237	0.088	Mouse Worm
oxoacid metabolic process	GO:0043436	31	0.088	Human
developmental growth	GO:0048589	166	0.086	Fly
reproduction	GO:0000003	40	0.085	Mouse Worm Fly
cellular response to chemical stimulus	GO:0070887	157	0.085	Human Mouse
eye field cell fate commitment involved in camera type eye formation	GO:0060898	3	0.085
protein modification process	GO:0036211	100	0.084	Human Worm
nuclear transport	GO:0051169	4	0.083
spermatogenesis	GO:0007283	7	0.083
signal transduction	GO:0007165	455	0.082	Human Zebrafish Mouse Worm Fly
regulation of binding	GO:0051098	3	0.082
proteolysis involved in cellular protein catabolic process	GO:0051603	3	0.082
embryonic organ morphogenesis	GO:0048562	274	0.081	Mouse
camera type eye development	GO:0043010	222	0.081	Mouse
keratinocyte differentiation	GO:0030216	0	0.080
modification dependent protein catabolic process	GO:0019941	3	0.080
determination of heart left right asymmetry	GO:0061371	117	0.079
regionalization	GO:0003002	274	0.079
brain development	GO:0007420	293	0.078	Mouse
neural tube development	GO:0021915	62	0.078
embryonic skeletal system development	GO:0048706	97	0.077	Mouse
regulation of cellular macromolecule biosynthetic process	GO:2000112	222	0.077	Human Mouse Worm Fly
mitotic cell cycle embryonic	GO:0045448	2	0.076	Mouse
negative regulation of macromolecule biosynthetic process	GO:0010558	48	0.076	Human Mouse
neuron projection guidance	GO:0097485	86	0.075
determination of bilateral symmetry	GO:0009855	204	0.075
extrinsic apoptotic signaling pathway	GO:0097191	3	0.074
response to external stimulus	GO:0009605	264	0.073
protein localization to nucleus	GO:0034504	3	0.073
heart looping	GO:0001947	94	0.072
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.071	Human Mouse Worm Fly
compound eye development	GO:0048749	2	0.071	Fly
connective tissue development	GO:0061448	99	0.071	Mouse
wnt signaling pathway involved in somitogenesis	GO:0090244	2	0.070
regeneration	GO:0031099	91	0.070
organelle localization	GO:0051640	49	0.070	Mouse
embryonic skeletal system morphogenesis	GO:0048704	93	0.070	Mouse
transport	GO:0006810	220	0.069	Human Mouse Worm
ras protein signal transduction	GO:0007265	7	0.069	Worm
positive regulation of multicellular organismal process	GO:0051240	52	0.069	Human Mouse Worm Fly
positive regulation of nitrogen compound metabolic process	GO:0051173	69	0.069	Human Mouse Worm Fly
neuron recognition	GO:0008038	18	0.068
protein catabolic process	GO:0030163	7	0.067
cellular protein modification process	GO:0006464	100	0.067	Human Worm
small gtpase mediated signal transduction	GO:0007264	8	0.067	Worm
establishment of epithelial cell polarity	GO:0090162	2	0.067
intracellular signal transduction	GO:0035556	85	0.067	Mouse Worm
defense response	GO:0006952	47	0.067
regulation of nucleocytoplasmic transport	GO:0046822	2	0.066
regulation of transport	GO:0051049	45	0.066	Human
negative regulation of biological process	GO:0048519	304	0.066	Human Zebrafish Mouse Worm Fly
single organism transport	GO:0044765	206	0.065	Human Mouse
gamete generation	GO:0007276	33	0.065	Mouse Fly
tissue regeneration	GO:0042246	74	0.064
regulation of receptor mediated endocytosis	GO:0048259	4	0.063
regulation of cell development	GO:0060284	100	0.063	Human Mouse
response to growth factor	GO:0070848	39	0.063	Human Mouse
positive regulation of cell cycle	GO:0045787	3	0.063
rna biosynthetic process	GO:0032774	181	0.062	Human Mouse Worm Fly
cellular amino acid metabolic process	GO:0006520	7	0.062
negative regulation of developmental process	GO:0051093	65	0.062	Zebrafish Mouse Fly
posttranscriptional regulation of gene expression	GO:0010608	14	0.062
regulation of gene expression	GO:0010468	265	0.062	Human Mouse Worm Fly
system process	GO:0003008	185	0.062	Fly
epithelial cell differentiation	GO:0030855	116	0.061	Mouse
transcription from rna polymerase ii promoter	GO:0006366	80	0.060	Human Mouse Worm Fly
regulation of response to stress	GO:0080134	36	0.060
negative regulation of transcription dna templated	GO:0045892	45	0.060	Human Mouse
regulation of locomotion	GO:0040012	55	0.060	Worm
organic cyclic compound metabolic process	GO:1901360	301	0.059	Human Mouse Worm Fly
cell projection organization	GO:0030030	284	0.059
positive regulation of cellular biosynthetic process	GO:0031328	68	0.059	Human Mouse Worm Fly
regulation of protein targeting	GO:1903533	2	0.057
germ cell development	GO:0007281	22	0.057	Mouse Fly
regulation of cell death	GO:0010941	103	0.057	Human Mouse
carboxylic acid metabolic process	GO:0019752	22	0.056
cellular ketone metabolic process	GO:0042180	11	0.056
positive regulation of cytosolic calcium ion concentration	GO:0007204	4	0.056
epithelial tube morphogenesis	GO:0060562	148	0.055	Human Mouse Fly
spermatid development	GO:0007286	2	0.055
programmed cell death	GO:0012501	119	0.055	Human Mouse Fly
establishment of apical basal cell polarity	GO:0035089	2	0.055
wound healing	GO:0042060	90	0.053
organic acid metabolic process	GO:0006082	31	0.053	Human
ion homeostasis	GO:0050801	41	0.052
cellular response to lipid	GO:0071396	39	0.052
regulation of growth	GO:0040008	42	0.052
regulation of rho protein signal transduction	GO:0035023	2	0.051
regulation of anatomical structure morphogenesis	GO:0022603	130	0.051	Human Mouse Fly
cellular response to extracellular stimulus	GO:0031668	2	0.050
regulation of nitrogen compound metabolic process	GO:0051171	251	0.050	Human Mouse Worm Fly
protein metabolic process	GO:0019538	183	0.049	Human Worm
adult behavior	GO:0030534	2	0.049
response to other organism	GO:0051707	97	0.049
cellular response to nutrient levels	GO:0031669	2	0.049
notch signaling pathway	GO:0007219	35	0.049
mesoderm development	GO:0007498	88	0.048
negative regulation of cellular process	GO:0048523	283	0.048	Human Zebrafish Mouse Fly
cellular macromolecule metabolic process	GO:0044260	391	0.048	Human Mouse Worm Fly
positive regulation of small gtpase mediated signal transduction	GO:0051057	1	0.047
muscle contraction	GO:0006936	18	0.047
cellular component maintenance	GO:0043954	3	0.047
retina development in camera type eye	GO:0060041	146	0.047
positive regulation of chromatin modification	GO:1903310	1	0.047
regulation of cellular amine metabolic process	GO:0033238	0	0.047
regulation of intracellular protein transport	GO:0033157	3	0.046
regulation of synapse assembly	GO:0051963	3	0.046
negative regulation of response to stimulus	GO:0048585	104	0.046	Zebrafish Mouse
positive regulation of chromosome organization	GO:2001252	1	0.045
heart morphogenesis	GO:0003007	156	0.045	Mouse Fly
regulation of mitotic cell cycle	GO:0007346	25	0.045	Mouse
negative regulation of cellular biosynthetic process	GO:0031327	55	0.045	Human Mouse
regulation of cell differentiation	GO:0045595	142	0.045	Human Mouse Worm Fly
regulation of organ morphogenesis	GO:2000027	35	0.045	Mouse Fly
embryonic eye morphogenesis	GO:0048048	30	0.045
negative regulation of mrna metabolic process	GO:1903312	3	0.044
specification of symmetry	GO:0009799	204	0.043
wnt signaling pathway involved in digestive tract morphogenesis	GO:0044333	4	0.043
negative regulation of metabolic process	GO:0009892	86	0.043	Human Mouse
cognition	GO:0050890	1	0.043	Fly
primary neural tube formation	GO:0014020	1	0.043
cellular response to acid chemical	GO:0071229	8	0.042
protein localization	GO:0008104	40	0.042	Human Mouse Worm Fly
small molecule metabolic process	GO:0044281	77	0.042	Human
positive regulation of transport	GO:0051050	2	0.042
embryonic heart tube morphogenesis	GO:0003143	108	0.042
cellular response to starvation	GO:0009267	1	0.042
regulation of signal transduction	GO:0009966	225	0.042	Zebrafish Mouse
cell junction maintenance	GO:0034331	2	0.041
regulation of nucleic acid templated transcription	GO:1903506	213	0.041	Human Mouse Worm Fly
muscle structure development	GO:0061061	196	0.041	Mouse
regulation of cellular protein metabolic process	GO:0032268	52	0.041	Human Worm
protein o linked glycosylation	GO:0006493	4	0.041
cell adhesion	GO:0007155	40	0.040	Human Mouse Worm Fly
ion transport	GO:0006811	114	0.040	Human
embryonic organ development	GO:0048568	381	0.040	Mouse
alternative mrna splicing via spliceosome	GO:0000380	1	0.040
cellular response to retinoic acid	GO:0071300	1	0.040
axis specification	GO:0009798	43	0.040
cell cell adhesion involved in gastrulation	GO:0070586	4	0.039
regulation of stem cell differentiation	GO:2000736	4	0.039	Human Fly
locomotion	GO:0040011	313	0.038	Mouse Worm
body morphogenesis	GO:0010171	16	0.038	Worm
actin filament based movement	GO:0030048	1	0.038
regulation of biosynthetic process	GO:0009889	250	0.038	Human Mouse Worm Fly
organonitrogen compound metabolic process	GO:1901564	74	0.038
wnt signaling pathway	GO:0016055	80	0.038	Human Zebrafish Mouse Worm Fly
ossification	GO:0001503	23	0.037	Mouse
neuron differentiation	GO:0030182	353	0.037	Fly
lamellipodium assembly	GO:0030032	1	0.037
regulation of cellular amino acid metabolic process	GO:0006521	0	0.037
canonical wnt signaling pathway	GO:0060070	48	0.037	Human Mouse Fly
somitogenesis	GO:0001756	87	0.036
blood vessel morphogenesis	GO:0048514	216	0.036	Mouse
negative regulation of calcium dependent cell cell adhesion	GO:0046588	1	0.036
proteasomal protein catabolic process	GO:0010498	2	0.036
polarized epithelial cell differentiation	GO:0030859	4	0.034
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	2	0.034	Worm
hepatocyte proliferation	GO:0072574	2	0.034
synaptic growth at neuromuscular junction	GO:0051124	2	0.034
taxis	GO:0042330	109	0.034
actin polymerization or depolymerization	GO:0008154	2	0.034
regulation of establishment of planar polarity	GO:0090175	4	0.034
growth	GO:0040007	174	0.033	Fly
regulation of localization	GO:0032879	104	0.033	Human Worm
central nervous system development	GO:0007417	387	0.033	Mouse
regulation of reproductive process	GO:2000241	4	0.033	Mouse
cellular response to organic substance	GO:0071310	105	0.033	Human Mouse
positive regulation of rna biosynthetic process	GO:1902680	57	0.033	Human Mouse Worm Fly
anatomical structure arrangement	GO:0048532	2	0.033
regulation of peptidyl tyrosine phosphorylation	GO:0050730	1	0.032
positive regulation of mrna metabolic process	GO:1903313	2	0.032
regulation of calcium dependent cell cell adhesion	GO:0046586	1	0.032
regulation of cytoplasmic transport	GO:1903649	4	0.032
eye morphogenesis	GO:0048592	144	0.032	Mouse Fly
blood circulation	GO:0008015	87	0.032
establishment of organelle localization	GO:0051656	45	0.032	Mouse
desmosome assembly	GO:0002159	2	0.032
erk1 and erk2 cascade	GO:0070371	4	0.032
positive regulation of developmental process	GO:0051094	50	0.031	Human Mouse Worm Fly
regulation of epithelial to mesenchymal transition	GO:0010717	3	0.031	Human
chordate embryonic development	GO:0043009	271	0.031	Mouse
positive regulation of apoptotic signaling pathway	GO:2001235	1	0.031
regulation of cell shape	GO:0008360	1	0.031	Fly
regulation of intracellular signal transduction	GO:1902531	57	0.031	Mouse
regulation of protein localization to nucleus	GO:1900180	2	0.031
single organism reproductive process	GO:0044702	40	0.030	Mouse Worm Fly
cell division	GO:0051301	20	0.030
regulation of cellular protein catabolic process	GO:1903362	1	0.030
cell growth	GO:0016049	57	0.030
cellular response to biotic stimulus	GO:0071216	3	0.030
macromolecular complex assembly	GO:0065003	35	0.030
nucleobase containing compound metabolic process	GO:0006139	274	0.030	Human Mouse Worm Fly
negative regulation of nucleic acid templated transcription	GO:1903507	45	0.030	Human Mouse
cellular amine metabolic process	GO:0044106	2	0.029
lamellipodium organization	GO:0097581	1	0.029
organic substance catabolic process	GO:1901575	28	0.029
response to biotic stimulus	GO:0009607	97	0.029
fertilization	GO:0009566	3	0.029
protein ubiquitination involved in ubiquitin dependent protein catabolic process	GO:0042787	1	0.029
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	1	0.029
regulation of synapse organization	GO:0050807	3	0.029
positive regulation of signaling	GO:0023056	56	0.028	Mouse
regulation of jun kinase activity	GO:0043506	3	0.028
ectoderm development	GO:0007398	9	0.028
regulation of cardiac muscle contraction	GO:0055117	2	0.028
regulation of purine nucleotide catabolic process	GO:0033121	2	0.028
regulation of protein ubiquitination	GO:0031396	3	0.028
metal ion homeostasis	GO:0055065	26	0.028
release of sequestered calcium ion into cytosol	GO:0051209	3	0.027
establishment of mitotic spindle localization	GO:0040001	12	0.027
embryonic camera type eye morphogenesis	GO:0048596	19	0.027
regulation of catalytic activity	GO:0050790	55	0.027	Mouse Worm
amine metabolic process	GO:0009308	2	0.027
regulation of cell proliferation	GO:0042127	37	0.027	Human Mouse
positive regulation of protein metabolic process	GO:0051247	23	0.027	Human Worm
activation of jun kinase activity	GO:0007257	2	0.026
cell proliferation	GO:0008283	80	0.026	Human Mouse Fly
regulation of protein transport	GO:0051223	3	0.026
epiboly	GO:0090504	41	0.026
cellular response to dna damage stimulus	GO:0006974	24	0.026
cell cell adhesion involved in mesendodermal cell migration	GO:0003370	1	0.026
intrinsic apoptotic signaling pathway	GO:0097193	20	0.026
cellular response to transforming growth factor beta stimulus	GO:0071560	7	0.026
establishment of monopolar cell polarity	GO:0061162	2	0.026
positive regulation of rna metabolic process	GO:0051254	59	0.026	Human Mouse Worm Fly
negative regulation of growth	GO:0045926	10	0.026
positive regulation of catalytic activity	GO:0043085	25	0.025	Mouse Worm
negative regulation of cell communication	GO:0010648	96	0.025	Zebrafish Mouse Fly
regulation of tube size	GO:0035150	2	0.025
response to fluid shear stress	GO:0034405	2	0.025
neural tube formation	GO:0001841	16	0.025
negative regulation of rna metabolic process	GO:0051253	48	0.025	Human Mouse
homeostatic process	GO:0042592	142	0.025	Mouse
regulation of response to cytokine stimulus	GO:0060759	3	0.025
convergent extension involved in gastrulation	GO:0060027	71	0.025
ear development	GO:0043583	127	0.025
macromolecular complex subunit organization	GO:0043933	74	0.024	Worm
regulation of eye photoreceptor cell development	GO:0042478	2	0.024
regulation of alternative mrna splicing via spliceosome	GO:0000381	1	0.024
regulation of gastrulation	GO:0010470	24	0.024
translational initiation	GO:0006413	3	0.024
regulation of meiotic cell cycle	GO:0051445	1	0.024
cellular process involved in reproduction in multicellular organism	GO:0022412	28	0.024	Mouse Fly
negative regulation of rna splicing	GO:0033119	1	0.024
macromolecule deacylation	GO:0098732	3	0.024
gtp catabolic process	GO:0006184	2	0.024
mitotic cell cycle process	GO:1903047	48	0.024	Worm
single organism cell adhesion	GO:0098602	29	0.024	Human Mouse Worm Fly
macromolecule modification	GO:0043412	111	0.024	Human Worm
optic placode formation involved in camera type eye formation	GO:0046619	3	0.024
regulation of cell communication	GO:0010646	232	0.024	Zebrafish Mouse Fly
phosphorus metabolic process	GO:0006793	109	0.024	Mouse Worm
negative regulation of nucleobase containing compound metabolic process	GO:0045934	59	0.024	Human Mouse
sex determination	GO:0007530	1	0.024
anterior head development	GO:0097065	2	0.024
morphogenesis of embryonic epithelium	GO:0016331	30	0.024	Mouse Fly
olfactory placode morphogenesis	GO:0071699	7	0.023
negative regulation of nitrogen compound metabolic process	GO:0051172	59	0.023	Human Mouse
positive regulation of gene expression	GO:0010628	71	0.023	Human Mouse Worm Fly
regulation of cellular ketone metabolic process	GO:0010565	7	0.023
neural tube patterning	GO:0021532	33	0.023
lipid storage	GO:0019915	1	0.023
determination of left right asymmetry in nervous system	GO:0035545	4	0.023
positive regulation of signal transduction	GO:0009967	56	0.023	Mouse
neural crest cell development	GO:0014032	62	0.023
regulation of cell division	GO:0051302	12	0.023
head development	GO:0060322	303	0.023	Mouse
negative regulation of cellular catabolic process	GO:0031330	3	0.022
response to drug	GO:0042493	3	0.022	Human
neural crest cell migration	GO:0001755	42	0.022
mesoderm morphogenesis	GO:0048332	51	0.022
sequestering of calcium ion	GO:0051208	3	0.022
biological adhesion	GO:0022610	40	0.022	Human Mouse Worm Fly
death	GO:0016265	121	0.022	Human Mouse Fly
axis elongation involved in somitogenesis	GO:0090245	2	0.022
neural crest formation	GO:0014029	14	0.022
regulation of translational initiation	GO:0006446	1	0.022
microtubule based process	GO:0007017	60	0.022	Human Worm
positive regulation of cellular component organization	GO:0051130	13	0.022	Human
negative regulation of rna biosynthetic process	GO:1902679	45	0.022	Human Mouse
cellular response to stress	GO:0033554	62	0.022
wnt signaling pathway planar cell polarity pathway	GO:0060071	4	0.021
mesenchymal cell differentiation	GO:0048762	87	0.021	Human
rna localization	GO:0006403	4	0.021
regulation of cellular component movement	GO:0051270	55	0.021	Worm
phosphorylation	GO:0016310	69	0.021	Mouse Worm
heart contraction	GO:0060047	71	0.021
caudal fin development	GO:0033336	9	0.021
determination of left right asymmetry in diencephalon	GO:0035462	4	0.021
autophagy	GO:0006914	4	0.021
response to transforming growth factor beta	GO:0071559	7	0.021
pole plasm assembly	GO:0007315	4	0.021
actin cytoskeleton organization	GO:0030036	63	0.021	Worm
guanosine containing compound metabolic process	GO:1901068	4	0.021
signal transduction by phosphorylation	GO:0023014	18	0.020	Mouse
cellular aromatic compound metabolic process	GO:0006725	295	0.020	Human Mouse Worm Fly
pigmentation	GO:0043473	85	0.020
bone mineralization	GO:0030282	9	0.020
spliceosomal complex assembly	GO:0000245	1	0.020
cellular response to external stimulus	GO:0071496	2	0.020
hindbrain development	GO:0030902	91	0.020
tube closure	GO:0060606	1	0.020
positive regulation of canonical wnt signaling pathway	GO:0090263	4	0.020
phosphate containing compound metabolic process	GO:0006796	108	0.020	Mouse Worm
establishment of spindle localization	GO:0051293	12	0.020
negative regulation of cell death	GO:0060548	60	0.020	Human Mouse
sensory organ morphogenesis	GO:0090596	200	0.019	Mouse Fly
circulatory system process	GO:0003013	87	0.019
spindle localization	GO:0051653	12	0.019
positive regulation of ras protein signal transduction	GO:0046579	1	0.019
stem cell proliferation	GO:0072089	4	0.019	Mouse
oxidation reduction process	GO:0055114	41	0.019
heterocycle metabolic process	GO:0046483	290	0.019	Human Mouse Worm Fly
apoptotic process	GO:0006915	116	0.019	Human Mouse
positive regulation of epithelial cell proliferation	GO:0050679	1	0.019	Mouse
regulation of erk1 and erk2 cascade	GO:0070372	4	0.019
regulation of bone mineralization	GO:0030500	2	0.019
negative regulation of mrna processing	GO:0050686	1	0.019
cellular hormone metabolic process	GO:0034754	19	0.019
divalent inorganic cation transport	GO:0072511	21	0.019	Human
neural crest cell differentiation	GO:0014033	72	0.019
post anal tail morphogenesis	GO:0036342	19	0.019
defense response to fungus	GO:0050832	2	0.019
regulation of developmental growth	GO:0048638	38	0.019
negative regulation of sequestering of calcium ion	GO:0051283	4	0.018
cytosolic calcium ion transport	GO:0060401	3	0.018
positive regulation of histone deacetylation	GO:0031065	1	0.018
positive regulation of nucleobase containing compound metabolic process	GO:0045935	69	0.018	Human Mouse Worm Fly
development of primary female sexual characteristics	GO:0046545	4	0.018
meiotic cell cycle process	GO:1903046	3	0.018
epithelium regeneration	GO:1990399	14	0.018
bmp signaling pathway	GO:0030509	52	0.018

ctnnb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.028
disease of cellular proliferation	DOID:14566	0.024	Human
cancer	DOID:162	0.021	Human
organ system cancer	DOID:0050686	0.021	Human
nervous system disease	DOID:863	0.021

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