Danio rerio

18 known processes

lnx2b

ligand of numb-protein X 2b

(Aliases: id:ibd3184,lnxL,MGC85925,MGC162185,zgc:85925)

lnx2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
digestive system developmentGO:00551232890.356
epithelial tube morphogenesisGO:00605621480.354
tube morphogenesisGO:00352393490.325
embryonic organ morphogenesisGO:00485622740.288
kidney developmentGO:0001822920.257
regulation of macromolecule biosynthetic processGO:00105562250.226
locomotionGO:00400113130.225
heart developmentGO:00075073130.211
regionalizationGO:00030022740.206
regulation of gene expressionGO:00104682650.203
cell projection organizationGO:00300302840.169
cell motilityGO:00488702440.166
cell migrationGO:00164772370.156
specification of symmetryGO:00097992040.140
cilium morphogenesisGO:0060271850.136
nephron morphogenesisGO:007202820.132
microtubule based movementGO:0007018330.123
cellular component movementGO:00069283350.119
determination of bilateral symmetryGO:00098552040.110
digestive tract morphogenesisGO:00485462310.104
regulation of biosynthetic processGO:00098892500.102
determination of left right symmetryGO:00073681790.097
regulation of signalingGO:00230512350.096
Fly
single organism reproductive processGO:0044702400.094
morphogenesis of an epitheliumGO:00020093330.085
nephron epithelium morphogenesisGO:007208810.083
regulation of rna metabolic processGO:00512522240.083
cell part morphogenesisGO:00329902460.082
cilium assemblyGO:0042384580.080
single organism organelle organizationGO:19025891990.080
kupffer s vesicle developmentGO:0070121500.079
sensory organ developmentGO:00074233930.077
bmp signaling pathwayGO:0030509520.077
cellular component assemblyGO:00226071700.073
cilium organizationGO:0044782710.072
urogenital system developmentGO:0001655970.069
central nervous system developmentGO:00074173870.069
determination of left right asymmetry in nervous systemGO:003554540.067
nitrogen compound metabolic processGO:00068073190.066
regulation of cellular biosynthetic processGO:00313262450.066
cell projection morphogenesisGO:00488582440.062
nuclear exportGO:005116810.058
regulation of multicellular organismal developmentGO:20000262230.057
regulation of epithelial cell proliferationGO:005067830.057
gastrulation with mouth forming secondGO:0001702440.055
regulation of wnt signaling pathway planar cell polarity pathwayGO:200009520.054
cell projection assemblyGO:0030031640.054
melanosome transportGO:0032402190.054
embryonic heart tube morphogenesisGO:00031431080.053
macromolecule biosynthetic processGO:00090592270.053
transcription dna templatedGO:00063511810.052
aromatic compound biosynthetic processGO:00194382170.052
rna metabolic processGO:00160702190.052
determination of left right asymmetry in diencephalonGO:003546240.051
anterior posterior pattern specificationGO:00099521520.050
cell morphogenesisGO:00009022890.048
cellular response to chemical stimulusGO:00708871570.047
renal tubule morphogenesisGO:006133310.047
nucleobase containing compound biosynthetic processGO:00346542050.046
negative regulation of biological processGO:00485193040.046
digestive tract developmentGO:00485652650.045
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.044
regulation of cardiac muscle tissue developmentGO:005502410.043
left right pattern formationGO:0060972190.042
cell adhesionGO:0007155400.042
regulation of cellular macromolecule biosynthetic processGO:20001122220.042
regulation of establishment of planar polarityGO:009017540.040
regulation of metal ion transportGO:001095940.040
cellular carbohydrate metabolic processGO:004426240.039
embryonic heart tube developmentGO:00350501330.039
biosynthetic processGO:00090582940.039
maintenance of locationGO:005123540.039
heart joggingGO:0003146400.036
axis elongationGO:0003401310.036
female meiotic divisionGO:000714320.036
cellular component morphogenesisGO:00329893360.036
cellular macromolecule metabolic processGO:00442603910.035
localization of cellGO:00516742440.034
glucocorticoid biosynthetic processGO:000670410.034
response to organic substanceGO:00100331530.034
system processGO:00030081850.034
Fly
organic cyclic compound biosynthetic processGO:19013622230.033
response to growth factorGO:0070848390.033
hormone biosynthetic processGO:004244630.033
cytoskeleton dependent intracellular transportGO:0030705100.033
regulation of primary metabolic processGO:00800903110.033
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.032
brain developmentGO:00074202930.032
regulation of cellular metabolic processGO:00313233200.031
segmentationGO:0035282970.031
centrosome duplicationGO:005129810.030
larval developmentGO:000216420.030
regulation of transcription from rna polymerase ii promoterGO:00063571140.030
centrosome cycleGO:000709810.029
ameboidal type cell migrationGO:00016671430.029
organelle organizationGO:00069962270.029
positive regulation of nitrogen compound metabolic processGO:0051173690.029
growthGO:00400071740.028
negative regulation of stem cell differentiationGO:200073720.028
regulation of rna biosynthetic processGO:20011412130.028
regulation of transcription dna templatedGO:00063552130.028
post golgi vesicle mediated transportGO:000689210.028
glucose homeostasisGO:004259310.028
sensory perceptionGO:0007600390.027
Fly
head developmentGO:00603223030.027
response to chemicalGO:00422213200.027
regulation of establishment of protein localizationGO:007020140.027
negative regulation of epithelial cell proliferationGO:005068010.027
striated muscle tissue developmentGO:00147061100.027
peptidyl serine modificationGO:001820920.027
transcription from rna polymerase ii promoterGO:0006366800.027
nucleobase containing compound metabolic processGO:00061392740.027
cellular component biogenesisGO:00440851780.027
nephron tubule morphogenesisGO:007207810.027
regulation of nucleobase containing compound metabolic processGO:00192192500.026
cell migration involved in gastrulationGO:0042074790.026
glycoprotein metabolic processGO:0009100230.026
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.026
gastrulationGO:00073692080.026
organic cyclic compound metabolic processGO:19013603010.025
agingGO:000756820.025
regulation of nitrogen compound metabolic processGO:00511712510.025
extrinsic apoptotic signaling pathwayGO:009719130.025
response to stressGO:00069502630.025
wnt signaling pathway planar cell polarity pathwayGO:006007140.025
microtubule organizing center organizationGO:003102310.024
nucleic acid metabolic processGO:00903042440.024
cellular nitrogen compound metabolic processGO:00346412900.024
regulation of cellular amine metabolic processGO:003323800.024
signal transductionGO:00071654550.024
Fly
multicellular organism growthGO:003526440.024
heterocycle biosynthetic processGO:00181302150.024
alcohol biosynthetic processGO:004616520.023
negative regulation of multicellular organismal processGO:0051241690.023
chordate embryonic developmentGO:00430092710.023
embryonic organ developmentGO:00485683810.022
organic substance biosynthetic processGO:19015762890.022
multi organism processGO:00517041340.022
mesenchyme developmentGO:00604851270.022
nucleic acid templated transcriptionGO:00976591810.022
ovulation cycleGO:004269820.022
cardiac atrium developmentGO:000323040.022
regulation of developmental processGO:00507932470.022
biological adhesionGO:0022610400.022
gene expressionGO:00104672520.022
regulation of heart growthGO:006042020.021
blood vessel developmentGO:00015682460.021
establishment of protein localization to plasma membraneGO:009000210.021
enzyme linked receptor protein signaling pathwayGO:00071671060.021
sulfur compound metabolic processGO:0006790130.021
embryo development ending in birth or egg hatchingGO:00097922710.020
regulation of nucleic acid templated transcriptionGO:19035062130.020
golgi vesicle transportGO:004819330.020
deathGO:00162651210.020
tube formationGO:0035148250.020
negative regulation of cell communicationGO:0010648960.020
rna biosynthetic processGO:00327741810.020
determination of heart left right asymmetryGO:00613711170.019
regulation of programmed cell deathGO:00430671010.019
cellular response to growth factor stimulusGO:0071363390.019
cell cell signalingGO:0007267520.019
regulation of macromolecule metabolic processGO:00602553170.019
regulation of response to stimulusGO:00485832690.019
Fly
regulation of metabolic processGO:00192223590.019
negative regulation of cellular processGO:00485232830.019
regulation of ectodermal cell fate specificationGO:004266520.019
heart loopingGO:0001947940.018
branching morphogenesis of an epithelial tubeGO:0048754150.018
erk1 and erk2 cascadeGO:007037140.018
cell substrate adhesionGO:003158940.018
regulation of receptor activityGO:001046920.018
organelle assemblyGO:00709251100.018
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.018
epithelial cell morphogenesisGO:000338220.018
megakaryocyte differentiationGO:003021910.018
regulation of transmembrane transporter activityGO:002289820.017
protein localization to plasma membraneGO:007265910.017
protein homooligomerizationGO:005126030.017
negative regulation of apoptotic processGO:0043066550.017
ectodermal cell fate specificationGO:000171520.017
regulation of neural precursor cell proliferationGO:200017730.017
positive regulation of translationGO:004572710.017
cell migration involved in mesendoderm migrationGO:009013420.017
regulation of nodal signaling pathwayGO:190010740.017
regulation of cytokine productionGO:000181730.017
specification of axis polarityGO:006500140.017
monovalent inorganic cation transportGO:0015672420.017
reproductive processGO:0022414400.017
ectoderm formationGO:000170520.016
mitotic cell cycle embryonicGO:004544820.016
centrosome organizationGO:005129710.016
camera type eye developmentGO:00430102220.016
cellular response to organic substanceGO:00713101050.016
negative regulation of wnt signaling pathwayGO:0030178300.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
stem cell maintenanceGO:001982740.016
vasculature developmentGO:00019442780.016
cellular macromolecule biosynthetic processGO:00346452240.016
transmission of nerve impulseGO:0019226190.016
organic acid metabolic processGO:0006082310.016
apoptotic process involved in developmentGO:190274220.016
eye developmentGO:00016542770.016
oxoacid metabolic processGO:0043436310.016
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.015
regulation of alcohol biosynthetic processGO:190293010.015
cellular response to drugGO:003569010.015
cellular biosynthetic processGO:00442492860.015
gtp metabolic processGO:004603940.015
tube closureGO:006060610.015
positive regulation of blood circulationGO:190352420.015
cellular modified amino acid metabolic processGO:000657530.015
macromolecule localizationGO:0033036540.015
cellular transition metal ion homeostasisGO:004691630.015
morphogenesis of an epithelial sheetGO:0002011490.015
positive regulation of muscle organ developmentGO:004863610.014
establishment of cell polarity involved in gastrulation cell migrationGO:000337920.014
zinc ion homeostasisGO:005506910.014
retina morphogenesis in camera type eyeGO:0060042790.014
regulation of transporter activityGO:003240920.014
positive regulation of striated muscle tissue developmentGO:004584410.014
negative regulation of gastrulationGO:2000542110.014
blood vessel morphogenesisGO:00485142160.014
proteasomal protein catabolic processGO:001049820.014
negative regulation of developmental processGO:0051093650.013
macromolecular complex assemblyGO:0065003350.013
negative regulation of gene expressionGO:0010629650.013
positive regulation of cell adhesionGO:004578510.013
anatomical structure arrangementGO:004853220.013
ovarian follicle developmentGO:000154120.013
axial mesoderm formationGO:004832040.013
muscle tissue developmentGO:00605371100.013
apoptotic processGO:00069151160.013
gamete generationGO:0007276330.013
cell matrix adhesionGO:000716040.013
regulation of ion transmembrane transporter activityGO:003241220.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
response to endogenous stimulusGO:0009719830.013
regulation of wnt signaling pathwayGO:0030111530.013
eye morphogenesisGO:00485921440.013
appendage morphogenesisGO:0035107560.013
gland developmentGO:00487321430.012
regulation of cardiac muscle cell differentiationGO:200072510.012
meiosis iiGO:000713510.012
endocardial cushion formationGO:000327220.012
peptide metabolic processGO:000651810.012
programmed cell deathGO:00125011190.012
regulation of cellular response to oxidative stressGO:190040720.012
oocyte maturationGO:000155640.012
cellular amino acid metabolic processGO:000652070.012
negative regulation of mesodermal cell fate specificationGO:004266230.012
cell deathGO:00082191210.012
protein stabilizationGO:005082120.012
nucleocytoplasmic transportGO:000691340.012
morphogenesis of a branching epitheliumGO:0061138160.012
regulation of multicellular organismal processGO:00512392770.012
response to other organismGO:0051707970.012
axis specificationGO:0009798430.012
regulation of cell communicationGO:00106462320.012
Fly
cellular protein catabolic processGO:004425740.012
positive regulation of biological processGO:00485182530.012
positive regulation of cellular amine metabolic processGO:003324000.012
heart contractionGO:0060047710.012
developmental growth involved in morphogenesisGO:0060560860.012
glucose importGO:004632320.012
intestinal cholesterol absorptionGO:003029920.011
regulation of embryonic developmentGO:0045995470.011
negative regulation of response to stimulusGO:00485851040.011
female sex differentiationGO:004666040.011
cellular localizationGO:0051641970.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.011
primary neural tube formationGO:001402010.011
cell substrate junction assemblyGO:000704420.011
regulation of oxidative stress induced cell deathGO:190320120.011
mesenchymal cell developmentGO:0014031780.011
cell surface receptor signaling pathwayGO:00071663250.011
Fly
regulation of wnt signaling pathway involved in digestive tract morphogenesisGO:200005620.011
carbohydrate homeostasisGO:003350010.011
regulation of mitotic cell cycle embryonicGO:000979420.011
developmental growthGO:00485891660.011
spindle assembly involved in meiosisGO:009030610.011
angioblast cell differentiationGO:003577920.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
establishment of pigment granule localizationGO:0051905220.011
negative regulation of myeloid cell differentiationGO:004563810.011
regulation of ectoderm developmentGO:200038320.011
positive regulation of rna metabolic processGO:0051254590.011
single organism transportGO:00447652060.011
embryonic limb morphogenesisGO:003032620.011
negative regulation of cell adhesionGO:000716260.011
regulation of epithelial to mesenchymal transitionGO:001071730.011
regulation of blood pressureGO:000821710.011
lipid storageGO:001991510.011
skeletal system morphogenesisGO:00487051020.011
regulation of bone mineralizationGO:003050020.011
maternal determination of anterior posterior axis embryoGO:000835840.011
synaptic vesicle recyclingGO:003646510.011
odontogenesis of dentin containing toothGO:004247510.011
negative regulation of myeloid leukocyte differentiationGO:000276210.011
smooth muscle contractionGO:000693920.010
specification of organ axis polarityGO:001008420.010
autophagyGO:000691440.010
hormone transportGO:000991420.010
regulation of apoptotic processGO:0042981980.010
melanin biosynthetic processGO:004243810.010
regulation of glucose importGO:004632410.010
female gonad developmentGO:000858540.010
regulation of multicellular organism growthGO:004001440.010
epithelial tube formationGO:0072175190.010
striated muscle cell differentiationGO:00511461290.010
phagocytosisGO:000690930.010
regulation of gastrulationGO:0010470240.010
endodermal digestive tract morphogenesisGO:006103120.010
response to dexamethasoneGO:007154810.010
heart morphogenesisGO:00030071560.010
negative regulation of cellular metabolic processGO:0031324770.010

lnx2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.053
nervous system diseaseDOID:86300.015
disease of metabolismDOID:001466700.013
amyotrophic lateral sclerosisDOID:33200.013
neurodegenerative diseaseDOID:128900.013
central nervous system diseaseDOID:33100.013
motor neuron diseaseDOID:23100.013
lysosomal storage diseaseDOID:321100.013
inherited metabolic disorderDOID:65500.013
musculoskeletal system diseaseDOID:1700.011