Danio rerio

80 known processes

slc8a1a

solute carrier family 8 (sodium/calcium exchanger), member 1a

(Aliases: ncx1,ncx1h)

slc8a1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
heart morphogenesisGO:00030071560.980
Zebrafish Mouse
heart developmentGO:00075073130.921
Zebrafish Mouse
cardiac muscle cell developmentGO:0055013200.899
Mouse
cardiac muscle cell differentiationGO:0055007300.881
Mouse
cardiac muscle tissue developmentGO:0048738480.873
Mouse
circulatory system processGO:0003013870.726
striated muscle cell differentiationGO:00511461290.682
actomyosin structure organizationGO:0031032530.654
striated muscle tissue developmentGO:00147061100.652
Zebrafish Mouse
muscle tissue developmentGO:00605371100.639
Zebrafish Mouse
heart contractionGO:0060047710.622
muscle structure developmentGO:00610611960.583
striated muscle cell developmentGO:00550021080.580
blood circulationGO:0008015870.575
muscle cell developmentGO:00550011150.573
specification of symmetryGO:00097992040.534
Zebrafish
cardiac myofibril assemblyGO:005500390.529
cardiac cell developmentGO:0055006210.523
Mouse
embryonic heart tube morphogenesisGO:00031431080.512
Zebrafish
cellular component morphogenesisGO:00329893360.511
ventricular cardiac muscle tissue morphogenesisGO:005501020.475
cardiocyte differentiationGO:0035051440.466
Mouse
cellular component assembly involved in morphogenesisGO:00109271070.458
ventricular cardiac muscle tissue developmentGO:000322930.457
heart loopingGO:0001947940.439
Zebrafish
regulation of muscle contractionGO:000693730.433
muscle cell differentiationGO:00426921390.429
heart processGO:0003015710.427
system processGO:00030081850.323
embryonic organ morphogenesisGO:00485622740.320
Zebrafish
myofibril assemblyGO:0030239480.305
determination of heart left right asymmetryGO:00613711170.268
Zebrafish
actin filament based processGO:0030029640.259
transmembrane transportGO:00550851200.257
larval developmentGO:000216420.239
embryonic organ developmentGO:00485683810.233
Zebrafish Mouse
regulation of blood circulationGO:1903522320.230
embryonic heart tube developmentGO:00350501330.211
Zebrafish Mouse
cardiac chamber formationGO:000320740.192
regulation of heart contractionGO:0008016320.191
inner ear developmentGO:00488391260.189
pigmentationGO:0043473850.187
heart joggingGO:0003146400.173
cardiac chamber morphogenesisGO:0003206120.171
organelle organizationGO:00069962270.171
regulation of multicellular organismal processGO:00512392770.166
single organism organelle organizationGO:19025891990.161
embryo development ending in birth or egg hatchingGO:00097922710.153
Mouse Worm
ear developmentGO:00435831270.149
regulation of system processGO:0044057400.143
cardiac muscle tissue morphogenesisGO:005500870.140
ion transportGO:00068111140.129
cardiac atrium morphogenesisGO:000320920.117
atrial cardiac myofibril assemblyGO:005500420.117
ventricular cardiac muscle cell differentiationGO:005501260.115
cellular component movementGO:00069283350.111
cardiac ventricle morphogenesisGO:000320870.110
determination of left right symmetryGO:00073681790.108
Zebrafish
outflow tract morphogenesisGO:000315110.107
neurological system processGO:0050877620.107
fin developmentGO:0033333770.103
cell part morphogenesisGO:00329902460.103
positive regulation of heart contractionGO:004582320.093
atrial cardiac muscle cell developmentGO:005501440.086
single organism localizationGO:19025782250.086
cognitionGO:005089010.086
morphogenesis of an epitheliumGO:00020093330.085
Zebrafish
tube morphogenesisGO:00352393490.084
Zebrafish
brain developmentGO:00074202930.082
neuron differentiationGO:00301823530.081
startle responseGO:000196440.079
establishment of localizationGO:00512342440.078
sensory organ developmentGO:00074233930.075
positive regulation of blood circulationGO:190352420.073
ribonucleoside monophosphate catabolic processGO:000915840.071
positive regulation of transportGO:005105020.070
maintenance of locationGO:005123540.070
neuron developmentGO:00486662620.070
cellular component biogenesisGO:00440851780.069
lipid storageGO:001991510.068
head developmentGO:00603223030.063
central nervous system developmentGO:00074173870.062
regulation of biological qualityGO:00650082630.062
artery developmentGO:0060840220.060
cardiac chamber developmentGO:0003205190.060
cell projection organizationGO:00300302840.060
multicellular organism growthGO:003526440.059
regulation of organ growthGO:004662030.058
cellular nitrogen compound metabolic processGO:00346412900.058
atrial cardiac muscle cell differentiationGO:005501150.057
ion transmembrane transportGO:0034220910.057
regulation of membrane repolarizationGO:006030610.056
muscle cell fate determinationGO:000752110.056
growthGO:00400071740.056
detection of mechanical stimulusGO:0050982110.055
cytoskeleton organizationGO:0007010960.055
appendage developmentGO:0048736800.055
developmental growthGO:00485891660.054
regulation of nucleoside metabolic processGO:000911820.054
cardiac conduction system developmentGO:000316110.054
cellular component assemblyGO:00226071700.053
determination of bilateral symmetryGO:00098552040.053
Zebrafish
cardiac ventricle developmentGO:000323190.052
heart valve formationGO:000318840.052
actin filament based movementGO:003004810.052
localization of cellGO:00516742440.051
pronephros developmentGO:0048793690.051
organic cyclic compound metabolic processGO:19013603010.050
adult behaviorGO:003053420.050
organelle assemblyGO:00709251100.050
vasculature developmentGO:00019442780.049
cytokinesisGO:000091030.048
regulation of purine nucleotide catabolic processGO:003312120.048
pectoral fin developmentGO:0033339500.048
muscle organ developmentGO:00075171010.047
Zebrafish
regulation of multicellular organism growthGO:004001440.046
nucleoside monophosphate catabolic processGO:000912540.046
inorganic cation transmembrane transportGO:0098662500.046
meiotic nuclear divisionGO:000712640.046
axon guidanceGO:0007411860.045
cell morphogenesis involved in neuron differentiationGO:00486671630.045
nitrogen compound metabolic processGO:00068073190.044
regulation of nitrogen compound metabolic processGO:00511712510.044
heterocycle metabolic processGO:00464832900.044
regulation of cell differentiationGO:00455951420.044
neuron projection morphogenesisGO:00488121610.042
regulation of cardiac muscle tissue developmentGO:005502410.041
digestive tract developmentGO:00485652650.041
cell motilityGO:00488702440.041
posterior lateral line developmentGO:0048916380.040
ventricular cardiac muscle cell developmentGO:005501550.040
cardiac atrium developmentGO:000323040.040
nitric oxide biosynthetic processGO:000680920.040
somatic muscle developmentGO:000752540.040
embryonic skeletal system morphogenesisGO:0048704930.039
response to mechanical stimulusGO:0009612240.039
epithelial tube morphogenesisGO:00605621480.038
Zebrafish
regulation of synapse assemblyGO:005196330.038
muscle contractionGO:0006936180.038
Mouse
regulation of heart morphogenesisGO:2000826170.037
endocardial cushion formationGO:000327220.037
medial fin developmentGO:0033338160.037
purine ribonucleoside monophosphate catabolic processGO:000916940.037
heart field specificationGO:000312810.036
endocardial cushion morphogenesisGO:000320330.036
embryonic skeletal joint developmentGO:007249830.036
regulation of nucleotide catabolic processGO:003081120.036
ventricular cardiac myofibril assemblyGO:005500540.036
gene expressionGO:00104672520.036
atrial ventricular junction remodelingGO:000329420.035
regulation of protein complex assemblyGO:004325430.035
pericardium developmentGO:006003910.035
regulation of bindingGO:005109830.035
chordate embryonic developmentGO:00430092710.035
Mouse
glial cell migrationGO:000834730.034
purine nucleoside monophosphate catabolic processGO:000912840.034
mesenchyme developmentGO:00604851270.034
cell migration involved in heart developmentGO:0060973220.033
atrioventricular valve developmentGO:0003171110.033
agingGO:000756820.033
cytoskeleton dependent cytokinesisGO:006164030.033
cellular biosynthetic processGO:00442492860.033
muscle organ morphogenesisGO:004864480.033
regulation of neurotransmitter transportGO:005158810.033
cell proliferation involved in heart morphogenesisGO:006132320.033
muscle system processGO:0003012200.033
Mouse
locomotionGO:00400113130.032
regulation of synapse organizationGO:005080730.032
nucleobase containing compound metabolic processGO:00061392740.032
atp catabolic processGO:000620040.032
epithelial cell differentiationGO:00308551160.032
oocyte anterior posterior axis specificationGO:000731440.031
segmentationGO:0035282970.031
neurotransmitter secretionGO:000726920.031
regulation of neurotransmitter secretionGO:004692810.031
regulation of synaptic growth at neuromuscular junctionGO:000858210.031
fin morphogenesisGO:0033334530.031
chemosensory behaviorGO:000763510.031
sodium ion transmembrane transportGO:0035725210.030
immune system developmentGO:00025201910.030
actin cytoskeleton organizationGO:0030036630.030
cardiac conductionGO:006133730.030
establishment of protein localization to organelleGO:007259440.030
cell migrationGO:00164772370.030
neurotransmitter transportGO:000683620.030
hematopoietic or lymphoid organ developmentGO:00485341910.030
regulation of localizationGO:00328791040.030
regulation of response to stimulusGO:00485832690.029
negative regulation of protein complex assemblyGO:003133310.029
cell morphogenesis involved in differentiationGO:00009041950.029
membrane repolarizationGO:008600920.029
response to topologically incorrect proteinGO:003596620.029
regulation of anatomical structure morphogenesisGO:00226031300.029
fin regenerationGO:0031101510.028
striated muscle contractionGO:0006941120.028
Mouse
muscle hypertrophyGO:001489620.028
negative regulation of synapse assemblyGO:005196420.028
cranial nerve developmentGO:0021545420.027
response to external stimulusGO:00096052640.027
transportGO:00068102200.027
cellular aromatic compound metabolic processGO:00067252950.027
neuron projection developmentGO:00311751800.027
regulation of cellular amine metabolic processGO:003323800.027
neuron fate determinationGO:004866420.027
regulation of developmental processGO:00507932470.026
regulation of reproductive processGO:200024140.026
blood vessel developmentGO:00015682460.026
trabecula morphogenesisGO:006138320.026
inner ear morphogenesisGO:0042472630.026
cardiac muscle cell contractionGO:008600310.026
photoreceptor cell fate commitmentGO:004655210.026
compound eye developmentGO:004874920.026
regenerationGO:0031099910.026
cell surface receptor signaling pathwayGO:00071663250.026
skeletal system developmentGO:00015011810.025
water homeostasisGO:003010440.025
regulation of apoptotic processGO:0042981980.025
muscle tissue morphogenesisGO:006041570.025
connective tissue developmentGO:0061448990.025
positive regulation of cytokine productionGO:000181920.025
aorta developmentGO:003590440.025
proepicardium developmentGO:000334240.025
exocytosisGO:000688710.024
cellular nitrogen compound biosynthetic processGO:00442712180.024
hemopoiesisGO:00300971830.024
tissue remodelingGO:004877140.024
regulation of cell proliferation involved in heart morphogenesisGO:200013620.024
regulation of actin filament based movementGO:190311510.024
cell deathGO:00082191210.024
lateral line system developmentGO:0048925760.024
positive regulation of striated muscle tissue developmentGO:004584410.024
rna biosynthetic processGO:00327741810.024
regulation of metabolic processGO:00192223590.024
synaptic growth at neuromuscular junctionGO:005112420.023
trabecula formationGO:006034320.023
posterior lateral line neuromast developmentGO:0048919200.023
endocardium morphogenesisGO:000316040.023
signal transductionGO:00071654550.023
lipid catabolic processGO:001604240.023
renal system developmentGO:0072001940.022
nerve developmentGO:0021675450.022
skeletal muscle organ developmentGO:0060538780.022
Zebrafish
cellular component disassemblyGO:002241110.022
rna localizationGO:000640340.022
reactive oxygen species biosynthetic processGO:190340910.022
positive regulation of muscle organ developmentGO:004863610.022
skeletal system morphogenesisGO:00487051020.022
sensory system developmentGO:0048880760.022
regulation of myotube differentiationGO:001083020.021
epidermal cell differentiationGO:0009913360.021
regulation of cardiac chamber formationGO:190121020.021
protein targeting to nucleusGO:004474430.021
stem cell maintenanceGO:001982740.021
multi organism processGO:00517041340.021
otolith developmentGO:0048840320.021
cellular localizationGO:0051641970.021
Mouse
regulation of protein bindingGO:004339330.021
regulation of cytokine productionGO:000181730.020
immune system processGO:00023762410.020
positive regulation of biological processGO:00485182530.020
gastrulationGO:00073692080.020
photoreceptor cell fate specificationGO:004370410.020
embryonic skeletal system developmentGO:0048706970.020
regulation of sequestering of calcium ionGO:005128240.020
regulation of gene expressionGO:00104682650.020
posterior lateral line neuromast hair cell differentiationGO:004892380.020
sensory organ morphogenesisGO:00905962000.020
regulation of cardiac muscle cell contractionGO:008600410.020
positive regulation of nucleotide catabolic processGO:003081310.020
regulation of transportGO:0051049450.020
regulation of primary metabolic processGO:00800903110.020
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.020
regulation of ventricular cardiac muscle cell membrane repolarizationGO:006030710.020
chloride transmembrane transportGO:190247640.019
mitotic cytokinesisGO:000028130.019
actin polymerization or depolymerizationGO:000815420.019
protein importGO:001703830.019
germ line stem cell maintenanceGO:003071820.019
positive regulation of cellular component biogenesisGO:004408930.019
negative regulation of metabolic processGO:0009892860.019
regulation of cardiac muscle contractionGO:005511720.019
positive regulation of cellular processGO:00485222010.019
cardiac muscle contractionGO:006004860.019
Mouse
response to stressGO:00069502630.019
mesoderm developmentGO:0007498880.019
cardiac ventricle formationGO:000321110.019
mesenchymal cell developmentGO:0014031780.019
calcium ion importGO:007050940.019
Mouse
regulation of epidermis developmentGO:004568220.019
nucleic acid templated transcriptionGO:00976591810.019
negative regulation of biological processGO:00485193040.018
transmission of nerve impulseGO:0019226190.018
single organism transportGO:00447652060.018
regulation of macromolecule metabolic processGO:00602553170.018
regulation of skeletal muscle tissue developmentGO:004864140.018
mechanosensory behaviorGO:000763820.018
caudal fin developmentGO:003333690.018
tissue regenerationGO:0042246740.018
regulation of protein import into nucleusGO:004230620.018
convergent extensionGO:00600261180.018
regulation of transporter activityGO:003240920.018
axon developmentGO:00615641660.017
retina development in camera type eyeGO:00600411460.017
organonitrogen compound metabolic processGO:1901564740.017
regulation of heart rateGO:000202750.017
Mouse
regulation of cellular amino acid metabolic processGO:000652100.017
embryonic hemopoiesisGO:0035162530.017
negative regulation of cytokine productionGO:000181810.017
cell projection morphogenesisGO:00488582440.017
regulation of cell matrix adhesionGO:000195210.017
circadian sleep wake cycle processGO:002241020.017
biosynthetic processGO:00090582940.017
sarcomere organizationGO:0045214260.017
atrioventricular valve formationGO:000319030.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
transcription dna templatedGO:00063511810.016
peripheral nervous system developmentGO:0007422550.016
rna metabolic processGO:00160702190.016
sensory perception of light stimulusGO:0050953190.016
response to chemicalGO:00422213200.016
Mouse
aorta morphogenesisGO:003590930.016
dorsal aorta morphogenesisGO:003591230.016
homeostatic processGO:00425921420.016
protein localization to nucleusGO:003450430.016
blood vessel morphogenesisGO:00485142160.016
negative regulation of protein phosphorylationGO:000193340.016
diencephalon developmentGO:0021536580.016
meiotic chromosome segregationGO:004513230.016
germ line stem cell divisionGO:004207810.015
protein metabolic processGO:00195381830.015
positive regulation of developmental processGO:0051094500.015
embryonic viscerocranium morphogenesisGO:0048703520.015
negative regulation of macromolecule metabolic processGO:0010605760.015
single organism metabolic processGO:00447102170.015
regulation of biosynthetic processGO:00098892500.015
epidermis developmentGO:0008544480.015
oligodendrocyte differentiationGO:0048709230.015
nucleic acid metabolic processGO:00903042440.015
cell cycleGO:0007049930.015
regulation of rna biosynthetic processGO:20011412130.015
metal ion transportGO:0030001580.015
neuron neuron synaptic transmissionGO:000727010.015
negative regulation of cellular processGO:00485232830.015
regulation of cellular component movementGO:0051270550.015
nitric oxide metabolic processGO:004620920.015
deathGO:00162651210.015
post embryonic morphogenesisGO:000988640.015
response to unfolded proteinGO:000698620.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
Mouse
rhombomere 5 developmentGO:002157140.015
regulation of multicellular organismal developmentGO:20000262230.015
regulation of ion transmembrane transporter activityGO:003241220.015
amine metabolic processGO:000930820.015
heterocycle biosynthetic processGO:00181302150.015
regulation of cellular biosynthetic processGO:00313262450.015
dna templated transcription initiationGO:000635210.015
regulation of transmembrane transporter activityGO:002289820.015
neural crest cell differentiationGO:0014033720.015
heart valve developmentGO:0003170140.014
post embryonic organ developmentGO:004856940.014
gtp catabolic processGO:000618420.014
specification of organ identityGO:001009220.014
chemotaxisGO:00069351040.014
regulation of cytoplasmic transportGO:190364940.014
ion homeostasisGO:0050801410.014
calcium mediated signalingGO:001972220.014
regulation of rna metabolic processGO:00512522240.014
cellular response to chemical stimulusGO:00708871570.014
Mouse
spermatid differentiationGO:004851520.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
negative regulation of gliogenesisGO:001401410.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
regulation of stem cell differentiationGO:200073640.014
heart valve morphogenesisGO:000317980.014
generation of neuronsGO:00486993850.014
posterior lateral line system developmentGO:0048915460.014
heart trabecula morphogenesisGO:006138420.014
cation homeostasisGO:0055080330.014
transcription from rna polymerase ii promoterGO:0006366800.014
regulation of striated muscle contractionGO:000694220.013
macromolecule biosynthetic processGO:00090592270.013
neuromuscular process controlling balanceGO:005088530.013
eye morphogenesisGO:00485921440.013
regulation of nucleocytoplasmic transportGO:004682220.013
regulation of erk1 and erk2 cascadeGO:007037240.013
mitochondrion organizationGO:000700540.013
digestive system developmentGO:00551232890.013
cellular amine metabolic processGO:004410620.013
negative regulation of heart contractionGO:004582220.013
regulation of organelle assemblyGO:190211540.013
catechol containing compound metabolic processGO:000971220.013
regulation of cellular component organizationGO:0051128860.013
caudal fin morphogenesisGO:003514370.013
regulation of synaptic plasticityGO:004816710.013
modification dependent macromolecule catabolic processGO:004363230.013
regulation of transmembrane transportGO:0034762180.013
regulation of cardiac chamber morphogenesisGO:190121920.013
action potentialGO:0001508190.013
regulation of macromolecule biosynthetic processGO:00105562250.013
small molecule catabolic processGO:004428230.013
cellular macromolecule metabolic processGO:00442603910.013
regulation of meiotic cell cycleGO:005144510.013
blood vessel endothelial cell differentiationGO:006083720.013
nuclear importGO:005117030.013
axial mesoderm developmentGO:0048318100.013
stem cell divisionGO:001714510.013
embryonic skeletal joint morphogenesisGO:006027230.013
negative regulation of gene expressionGO:0010629650.013
neuromast developmentGO:0048884460.013
regulation of wound healingGO:006104120.012
cell migration involved in gastrulationGO:0042074790.012
phosphatidylinositol 3 kinase signalingGO:001406520.012
sarcomerogenesisGO:004876940.012
endoplasmic reticulum unfolded protein responseGO:003096820.012
photoreceptor cell differentiationGO:0046530550.012
regulation of cellular metabolic processGO:00313233200.012
regulation of cell activationGO:005086510.012
cartilage developmentGO:0051216960.012
homeostasis of number of cellsGO:0048872620.012
positive regulation of catabolic processGO:000989640.012
positive regulation of nucleobase containing compound metabolic processGO:0045935690.012
cation transmembrane transportGO:0098655650.012
regulation of nucleotide metabolic processGO:0006140170.012
regulation of heart growthGO:006042020.012
sensory perceptionGO:0007600390.012
urogenital system developmentGO:0001655970.012
forebrain developmentGO:0030900960.012
response to abiotic stimulusGO:00096281220.012
endocardium developmentGO:000315790.012
leukocyte proliferationGO:007066110.012
regionalizationGO:00030022740.012
regulation of circadian rhythmGO:004275240.012
regulation of protein transportGO:005122330.012
pharyngeal muscle developmentGO:004328240.012
septum transversum developmentGO:000334340.011
venous blood vessel developmentGO:006084190.011
mesenchymal cell proliferationGO:001046310.011
artery morphogenesisGO:0048844140.011
angiogenesisGO:00015251580.011
intermediate mesoderm developmentGO:004838920.011
regulation of nucleobase containing compound metabolic processGO:00192192500.011
regulation of filopodium assemblyGO:005148920.011
skin developmentGO:0043588540.011
regulation of membrane potentialGO:0042391230.011
wound healingGO:0042060900.011
cell proliferationGO:0008283800.011
phosphate containing compound metabolic processGO:00067961080.011
phagocytosis engulfmentGO:000691110.011
positive regulation of cell adhesionGO:004578510.011
divalent inorganic cation homeostasisGO:0072507220.011
carbohydrate derivative metabolic processGO:1901135610.011
cellular response to topologically incorrect proteinGO:003596720.011
intracellular mrna localizationGO:000829810.011
regulation of neuron apoptotic processGO:0043523170.011
cellular response to endogenous stimulusGO:0071495680.011
Mouse
regulation of cell projection assemblyGO:006049140.011
g1 s transition of mitotic cell cycleGO:000008210.011
regulation of signalingGO:00230512350.011
positive regulation of muscle tissue developmentGO:190186310.011
inorganic ion transmembrane transportGO:0098660570.011
positive regulation of secretionGO:005104710.011
gland developmentGO:00487321430.011
organic substance biosynthetic processGO:19015762890.011
regulation of blood pressureGO:000821710.011
Mouse
cell differentiation in spinal cordGO:0021515400.011
cellular ketone metabolic processGO:0042180110.011
cell cell signalingGO:0007267520.011
cellular protein catabolic processGO:004425740.011
negative regulation of apoptotic processGO:0043066550.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.010
regulation of ion transmembrane transportGO:0034765180.010
modification dependent protein catabolic processGO:001994130.010
specification of organ positionGO:001015930.010
meiotic cell cycle processGO:190304630.010
neural tube patterningGO:0021532330.010
regulation of skeletal muscle fiber developmentGO:004874220.010
rhombomere 6 developmentGO:002157240.010
ear morphogenesisGO:0042471640.010
kidney developmentGO:0001822920.010
cation transportGO:0006812810.010
hormone secretionGO:004687920.010
regulation of tube sizeGO:003515020.010
Mouse
detection of stimulusGO:0051606290.010
protein polymerizationGO:005125840.010

slc8a1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.197
cardiomyopathyDOID:005070000.197
musculoskeletal system diseaseDOID:1700.197
muscle tissue diseaseDOID:6600.197
heart diseaseDOID:11400.197
intrinsic cardiomyopathyDOID:006003600.197
hypertrophic cardiomyopathyDOID:1198400.197
muscular diseaseDOID:008000000.197
myopathyDOID:42300.197
cardiovascular system diseaseDOID:128700.197
dilated cardiomyopathyDOID:1293000.021