Danio rerio

0 known processes

mcm6

MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)

(Aliases: im:7140796,MGC158377,cb800,wu:fc26f09,wu:fb30d05)

mcm6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
locomotionGO:00400113130.507
cellular component movementGO:00069283350.403
cellular nitrogen compound metabolic processGO:00346412900.375
Human Mouse Fly
heart developmentGO:00075073130.361
cellular aromatic compound metabolic processGO:00067252950.355
Human Mouse Fly
embryo development ending in birth or egg hatchingGO:00097922710.321
Worm
localization of cellGO:00516742440.317
regulation of metabolic processGO:00192223590.303
cell surface receptor signaling pathwayGO:00071663250.302
nitrogen compound metabolic processGO:00068073190.286
Human Mouse Fly
gtp metabolic processGO:004603940.234
guanosine containing compound metabolic processGO:190106840.233
meiotic cell cycle processGO:190304630.233
heterocycle catabolic processGO:0046700150.227
Human
nucleobase containing compound metabolic processGO:00061392740.225
Human Mouse Fly
gtp catabolic processGO:000618420.216
meiotic nuclear divisionGO:000712640.209
single organism organelle organizationGO:19025891990.196
organic cyclic compound metabolic processGO:19013603010.193
Human Mouse Fly
cell motilityGO:00488702440.186
gene expressionGO:00104672520.180
regulation of nitrogen compound metabolic processGO:00511712510.176
blood vessel developmentGO:00015682460.173
regulation of nucleotide catabolic processGO:003081120.172
regulation of gtp catabolic processGO:003312420.163
negative regulation of cellular processGO:00485232830.156
cell migrationGO:00164772370.154
positive regulation of gtpase activityGO:004354710.148
heterocycle metabolic processGO:00464832900.145
Human Mouse Fly
nucleobase containing compound biosynthetic processGO:00346542050.140
Fly
organelle organizationGO:00069962270.140
stem cell maintenanceGO:001982740.136
cellular component biogenesisGO:00440851780.135
response to stressGO:00069502630.133
regulation of purine nucleotide catabolic processGO:003312120.132
regulation of nucleobase containing compound metabolic processGO:00192192500.131
maintenance of locationGO:005123540.131
regulation of biological qualityGO:00650082630.128
aromatic compound biosynthetic processGO:00194382170.128
Fly
actin filament based processGO:0030029640.127
cell projection organizationGO:00300302840.124
modification dependent macromolecule catabolic processGO:004363230.118
transcription dna templatedGO:00063511810.116
immune system processGO:00023762410.114
regulation of primary metabolic processGO:00800903110.113
modification dependent protein catabolic processGO:001994130.112
positive regulation of biological processGO:00485182530.112
regulation of gene expressionGO:00104682650.109
regulation of response to stimulusGO:00485832690.108
regulation of cellular metabolic processGO:00313233200.108
regulation of purine nucleotide metabolic processGO:1900542170.108
cellular component assemblyGO:00226071700.107
guanosine containing compound catabolic processGO:190106920.107
organic cyclic compound biosynthetic processGO:19013622230.106
Fly
chordate embryonic developmentGO:00430092710.105
cytoskeleton dependent cytokinesisGO:006164030.104
embryonic heart tube developmentGO:00350501330.104
positive regulation of nucleoside metabolic processGO:004597910.101
lipid storageGO:001991510.099
g1 s transition of mitotic cell cycleGO:000008210.098
cell deathGO:00082191210.098
larval developmentGO:000216420.097
signal transductionGO:00071654550.096
meiotic chromosome segregationGO:004513230.092
generation of neuronsGO:00486993850.091
organic substance biosynthetic processGO:19015762890.091
Mouse Fly
cellular macromolecular complex assemblyGO:0034622240.089
regulation of nucleoside metabolic processGO:000911820.089
leukocyte proliferationGO:007066110.088
vasculature developmentGO:00019442780.085
positive regulation of purine nucleotide catabolic processGO:003312310.082
regulation of cellular component organizationGO:0051128860.082
nucleic acid templated transcriptionGO:00976591810.081
organophosphate metabolic processGO:0019637370.078
Human
regulation of gtpase activityGO:004308720.077
cytokinesisGO:000091030.076
organelle fusionGO:004828430.075
organelle assemblyGO:00709251100.074
positive regulation of cell cycleGO:004578730.072
cellular biosynthetic processGO:00442492860.072
Mouse Fly
oocyte maturationGO:000155640.070
female meiotic divisionGO:000714320.070
negative regulation of chromosome organizationGO:200125110.069
chromosome segregationGO:0007059120.069
positive regulation of nitrogen compound metabolic processGO:0051173690.067
regulation of meiotic cell cycleGO:005144510.066
nucleic acid metabolic processGO:00903042440.066
Human Mouse Fly
actin filament polymerizationGO:003004120.062
specification of symmetryGO:00097992040.062
nuclear migrationGO:000709730.061
nucleocytoplasmic transportGO:000691340.061
immune system developmentGO:00025201910.060
regulation of macromolecule metabolic processGO:00602553170.059
proteasomal protein catabolic processGO:001049820.059
regulation of cellular biosynthetic processGO:00313262450.059
cell part morphogenesisGO:00329902460.058
neuron developmentGO:00486662620.058
regulation of rho protein signal transductionGO:003502320.058
muscle structure developmentGO:00610611960.057
positive regulation of gtp catabolic processGO:003312610.057
regulation of signalingGO:00230512350.057
cellular protein catabolic processGO:004425740.057
single organism transportGO:00447652060.057
macromolecular complex assemblyGO:0065003350.056
purine nucleotide metabolic processGO:0006163270.056
Human
cellular protein complex assemblyGO:0043623190.055
protein stabilizationGO:005082120.054
developmental growthGO:00485891660.054
microtubule based processGO:0007017600.054
striated muscle cell differentiationGO:00511461290.054
heterocycle biosynthetic processGO:00181302150.054
Fly
cellular nitrogen compound biosynthetic processGO:00442712180.053
Fly
muscle cell differentiationGO:00426921390.051
positive regulation of hydrolase activityGO:0051345130.050
regulation of transcription dna templatedGO:00063552130.050
proteolysis involved in cellular protein catabolic processGO:005160330.050
somite developmentGO:0061053960.049
system processGO:00030081850.048
programmed cell deathGO:00125011190.047
cytoskeleton organizationGO:0007010960.047
production of molecular mediator of immune responseGO:000244020.047
regulation of multicellular organism growthGO:004001440.046
regulation of synapse organizationGO:005080730.046
response to woundingGO:00096111160.046
cell cycle g1 s phase transitionGO:004484310.045
rna biosynthetic processGO:00327741810.045
regulation of collateral sprouting of intact axon in response to injuryGO:004868320.044
organonitrogen compound metabolic processGO:1901564740.044
Human
regulation of cell communicationGO:00106462320.043
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.043
microtubule cytoskeleton organization involved in mitosisGO:190285010.043
wound healingGO:0042060900.043
establishment of protein localization to organelleGO:007259440.043
angiogenesisGO:00015251580.042
regulation of nucleic acid templated transcriptionGO:19035062130.042
regulation of cellular macromolecule biosynthetic processGO:20001122220.042
actin polymerization or depolymerizationGO:000815420.042
cellular nitrogen compound catabolic processGO:0044270150.042
Human
somatic muscle developmentGO:000752540.042
regulation of biosynthetic processGO:00098892500.041
cellular macromolecule metabolic processGO:00442603910.040
Human Mouse Fly
hematopoietic or lymphoid organ developmentGO:00485341910.040
homeostatic processGO:00425921420.040
regulation of developmental processGO:00507932470.040
mitotic cytokinesisGO:000028130.040
protein metabolic processGO:00195381830.039
single organism metabolic processGO:00447102170.039
Human Fly
negative regulation of apoptotic processGO:0043066550.038
regulation of macromolecule biosynthetic processGO:00105562250.038
regulation of chromosome segregationGO:005198310.037
regulation of dna replicationGO:000627530.037
primary neural tube formationGO:001402010.036
transmembrane transportGO:00550851200.035
regenerationGO:0031099910.035
hematopoietic stem cell migrationGO:003570140.035
sprouting angiogenesisGO:0002040530.035
ubiquitin dependent protein catabolic processGO:000651130.035
rna metabolic processGO:00160702190.034
mitotic g2 dna damage checkpointGO:000709530.034
negative regulation of rna biosynthetic processGO:1902679450.034
positive regulation of ras gtpase activityGO:003232010.034
enzyme linked receptor protein signaling pathwayGO:00071671060.034
double strand break repairGO:000630230.034
angioblast cell migration involved in selective angioblast sproutingGO:003547540.034
positive regulation of cellular catabolic processGO:003133130.034
adherens junction maintenanceGO:003433420.034
blood vessel endothelial cell proliferation involved in sprouting angiogenesisGO:000204340.033
synaptic growth at neuromuscular junctionGO:005112420.033
protein polymerizationGO:005125840.033
regulation of signal transductionGO:00099662250.033
antimicrobial humoral responseGO:001973020.033
nucleobase containing compound catabolic processGO:0034655150.033
Human
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.033
positive regulation of catabolic processGO:000989640.033
negative regulation of nuclear divisionGO:005178430.033
positive regulation of metabolic processGO:00098931080.032
embryonic organ developmentGO:00485683810.032
negative regulation of dna metabolic processGO:005105340.032
cellular component maintenanceGO:004395430.032
nucleobase containing small molecule metabolic processGO:0055086320.032
Human
regulation of stem cell differentiationGO:200073640.032
chromatin organizationGO:0006325220.032
determination of bilateral symmetryGO:00098552040.031
regulation of rna biosynthetic processGO:20011412130.031
inorganic anion transportGO:0015698250.031
eye morphogenesisGO:00485921440.031
regulation of rna metabolic processGO:00512522240.031
mitotic cell cycleGO:0000278640.031
female gamete generationGO:0007292140.031
Worm Fly
regulation of neuron differentiationGO:0045664560.031
regulation of cellular ketone metabolic processGO:001056570.030
peptidyl serine phosphorylationGO:001810510.030
glial cell differentiationGO:0010001420.030
multicellular organism growthGO:003526440.029
cell proliferationGO:0008283800.029
macromolecular complex subunit organizationGO:0043933740.029
negative regulation of signal transductionGO:0009968940.029
deathGO:00162651210.029
positive regulation of nucleobase containing compound metabolic processGO:0045935690.029
regulation of ras gtpase activityGO:003231820.029
cranial nerve developmentGO:0021545420.029
actin filament organizationGO:0007015150.029
cellular component morphogenesisGO:00329893360.028
Fly
sulfate transportGO:000827220.028
establishment of localizationGO:00512342440.028
epithelial cell morphogenesisGO:000338220.028
positive regulation of nucleic acid templated transcriptionGO:1903508570.028
negative regulation of macromolecule biosynthetic processGO:0010558480.028
regulation of protein complex assemblyGO:004325430.028
lymphatic endothelial cell fate commitmentGO:006083810.028
rho protein signal transductionGO:000726650.027
lipid oxidationGO:003444010.027
negative regulation of metabolic processGO:0009892860.027
stem cell proliferationGO:007208940.027
embryonic organ morphogenesisGO:00485622740.027
germ cell developmentGO:0007281220.027
Worm Fly
purine containing compound metabolic processGO:0072521290.027
Human
positive regulation of protein polymerizationGO:003227320.026
methylationGO:0032259220.026
endothelial cell fate commitmentGO:006083930.026
digestive system developmentGO:00551232890.026
stem cell differentiationGO:00488631170.026
positive regulation of cellular processGO:00485222010.026
regulation of synaptic growth at neuromuscular junctionGO:000858210.026
chromosome organizationGO:0051276310.026
actomyosin structure organizationGO:0031032530.026
blood vessel morphogenesisGO:00485142160.026
regulation of nucleotide metabolic processGO:0006140170.025
negative regulation of signalingGO:0023057960.025
protein complex localizationGO:003150310.025
skeletal system developmentGO:00015011810.025
negative regulation of synapse assemblyGO:005196420.025
aromatic compound catabolic processGO:0019439150.025
Human
negative regulation of nitrogen compound metabolic processGO:0051172590.025
negative regulation of cellular metabolic processGO:0031324770.024
somitogenesisGO:0001756870.024
germ line stem cell maintenanceGO:003071820.024
single organism localizationGO:19025782250.024
digestive tract developmentGO:00485652650.024
cellular response to chemical stimulusGO:00708871570.024
embryonic digestive tract morphogenesisGO:004855730.024
regulation of organ growthGO:004662030.023
positive regulation of cellular metabolic processGO:0031325940.023
mesenchymal cell proliferationGO:001046310.023
cellular ketone metabolic processGO:0042180110.023
regulation of rho gtpase activityGO:003231910.022
agingGO:000756820.022
carbohydrate derivative metabolic processGO:1901135610.022
Human
peripheral nervous system neuron differentiationGO:0048934280.022
cell morphogenesis involved in neuron differentiationGO:00486671630.022
macromolecule biosynthetic processGO:00090592270.022
Mouse Fly
cellular localizationGO:0051641970.022
regulation of anatomical structure morphogenesisGO:00226031300.022
neuroblast proliferationGO:000740520.022
negative regulation of biological processGO:00485193040.022
dna metabolic processGO:0006259270.022
Human Mouse Fly
single organism membrane fusionGO:004480120.022
regulation of cytoplasmic transportGO:190364940.022
determination of left right symmetryGO:00073681790.021
innate immune responseGO:0045087130.021
mesenchymal cell developmentGO:0014031780.021
regulation of oocyte developmentGO:006028130.021
cell morphogenesisGO:00009022890.021
single organism membrane organizationGO:0044802200.021
hemopoiesisGO:00300971830.021
retina morphogenesis in camera type eyeGO:0060042790.021
cell projection morphogenesisGO:00488582440.021
cellular protein complex localizationGO:003462910.021
regulation of hydrolase activityGO:0051336280.020
negative regulation of biosynthetic processGO:0009890550.020
positive regulation of nucleotide catabolic processGO:003081310.020
meiotic cell cycleGO:005132150.020
regulation of cell migrationGO:0030334400.020
negative regulation of developmental processGO:0051093650.020
tube morphogenesisGO:00352393490.019
axon developmentGO:00615641660.019
regulation of wnt signaling pathwayGO:0030111530.019
small molecule metabolic processGO:0044281770.019
Human
cellular response to organic substanceGO:00713101050.019
embryonic skeletal joint morphogenesisGO:006027230.019
positive regulation of purine nucleotide metabolic processGO:190054490.019
negative regulation of nucleobase containing compound metabolic processGO:0045934590.019
biosynthetic processGO:00090582940.019
Mouse Fly
negative regulation of mesodermal cell fate specificationGO:004266230.019
stem cell fate commitmentGO:004886510.019
sensory organ developmentGO:00074233930.019
regulation of multicellular organismal developmentGO:20000262230.019
negative regulation of collateral sproutingGO:004867120.018
regulation of cell shapeGO:000836010.018
regulation of cellular component movementGO:0051270550.018
vestibular receptor cell developmentGO:006011830.018
negative regulation of response to stimulusGO:00485851040.018
regulation of cell deathGO:00109411030.018
response to chemicalGO:00422213200.018
negative regulation of cell communicationGO:0010648960.018
negative regulation of wnt signaling pathwayGO:0030178300.018
regulation of gene expression epigeneticGO:0040029110.018
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.018
cardiac atrium developmentGO:000323040.018
mononuclear cell proliferationGO:003294310.018
cellular response to stressGO:0033554620.018
organ regenerationGO:003110010.018
muscle cell developmentGO:00550011150.018
spindle assembly involved in mitosisGO:009030710.017
protein localizationGO:0008104400.017
regulation of catalytic activityGO:0050790550.017
regulation of jun kinase activityGO:004350630.017
response to external stimulusGO:00096052640.017
positive regulation of molecular functionGO:0044093330.017
regulation of bindingGO:005109830.017
dorsal motor nucleus of vagus nerve developmentGO:002174440.017
morphogenesis of an epitheliumGO:00020093330.017
tube closureGO:006060610.017
negative regulation of cell cycle processGO:001094890.017
regulation of axon regenerationGO:004867970.017
response to carbohydrateGO:000974330.017
regulation of dendrite developmentGO:005077330.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of cell cycle processGO:0010564200.016
nuclear transportGO:005116940.016
b cell activationGO:004211320.016
striated muscle tissue developmentGO:00147061100.016
intracellular signal transductionGO:0035556850.016
ameboidal type cell migrationGO:00016671430.016
cardiac atrium morphogenesisGO:000320920.016
medulla oblongata developmentGO:002155040.016
purine ribonucleoside monophosphate catabolic processGO:000916940.016
Human
striated muscle cell developmentGO:00550021080.016
digestive tract mesoderm developmentGO:000750210.016
negative regulation of transcription dna templatedGO:0045892450.016
ion transmembrane transportGO:0034220910.016
regulation of reproductive processGO:200024140.015
cellular response to external stimulusGO:007149620.015
peptidyl serine modificationGO:001820920.015
regulation of cell motilityGO:2000145460.015
actin cytoskeleton organizationGO:0030036630.015
meiosis iGO:000712710.015
cellular component assembly involved in morphogenesisGO:00109271070.015
Fly
transportGO:00068102200.015
regulation of programmed cell deathGO:00430671010.015
peripheral nervous system neuron developmentGO:0048935220.015
regulation of cell differentiationGO:00455951420.014
regulation of protein catabolic processGO:004217610.014
cell fate commitmentGO:0045165990.014
Fly
regulation of epithelial to mesenchymal transitionGO:001071730.014
neuroblast differentiationGO:001401610.014
single organism nuclear importGO:190259330.014
ribosomal small subunit biogenesisGO:004227420.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.014
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.014
mrna processingGO:0006397140.014
positive regulation of cytoskeleton organizationGO:005149530.014
single organism biosynthetic processGO:0044711710.014
Fly
cell junction maintenanceGO:003433120.014
g2 dna damage checkpointGO:003157230.014
regulation of mesenchymal cell proliferationGO:001046410.014
single organism cellular localizationGO:1902580460.014
regulation of mrna splicing via spliceosomeGO:004802430.014
cranial nerve morphogenesisGO:0021602150.014
angioblast cell migrationGO:003547690.014
retina development in camera type eyeGO:00600411460.014
negative regulation of rna metabolic processGO:0051253480.014
regulation of apoptotic processGO:0042981980.014
proteolysisGO:0006508380.013
regulation of tube sizeGO:003515020.013
skeletal muscle organ developmentGO:0060538780.013
cell migration involved in sprouting angiogenesisGO:000204280.013
regulation of cell developmentGO:00602841000.013
regulation of synapse assemblyGO:005196330.013
regulation of cell cycle phase transitionGO:190198780.013
erythrocyte homeostasisGO:0034101550.013
protein homooligomerizationGO:005126030.013
negative regulation of nucleic acid templated transcriptionGO:1903507450.013
acylglycerol homeostasisGO:005509020.013
chemotaxisGO:00069351040.013
macromolecule catabolic processGO:0009057150.013
ribose phosphate metabolic processGO:0019693270.013
Human
regulation of mrna processingGO:005068430.013
negative regulation of mitosisGO:004583930.013
glycosyl compound metabolic processGO:1901657110.013
Human
positive regulation of cellular component biogenesisGO:004408930.013
positive regulation of muscle tissue developmentGO:190186310.013
regulation of cellular amine metabolic processGO:003323800.013
phagocytosisGO:000690930.013
cellular macromolecule biosynthetic processGO:00346452240.012
Mouse Fly
regulation of nucleocytoplasmic transportGO:004682220.012
embryonic skeletal system morphogenesisGO:0048704930.012
positive regulation of gene expressionGO:0010628710.012
neuron projection developmentGO:00311751800.012
anterior posterior pattern specificationGO:00099521520.012
smooth muscle contractionGO:000693920.012
regulation of cell migration involved in sprouting angiogenesisGO:009004930.012
negative regulation of macromolecule metabolic processGO:0010605760.012
myeloid cell developmentGO:0061515320.012
regulation of molecular functionGO:0065009700.012
purine ribonucleotide metabolic processGO:0009150270.012
Human
regulation of multicellular organismal processGO:00512392770.012
connective tissue developmentGO:0061448990.012
cell projection assemblyGO:0030031640.012
tissue regenerationGO:0042246740.012
regulation of cell activationGO:005086510.012
regulation of histone h3 k9 methylationGO:005157020.012
wnt signaling pathwayGO:0016055800.012
negative regulation of mitotic cell cycleGO:0045930110.012
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.012
skeletal muscle tissue developmentGO:0007519670.012
digestive tract morphogenesisGO:00485462310.012
g2 m transition of mitotic cell cycleGO:000008640.011
cellular protein localizationGO:0034613200.011
negative regulation of catabolic processGO:000989530.011
action potentialGO:0001508190.011
lymphatic endothelial cell differentiationGO:006083610.011
purine ribonucleoside metabolic processGO:0046128100.011
Human
positive regulation of rna metabolic processGO:0051254590.011
protein localization to plasma membraneGO:007265910.011
organic cyclic compound catabolic processGO:1901361150.011
Human
regulation of cell projection assemblyGO:006049140.011
gene silencingGO:001645840.011
negative regulation of cellular catabolic processGO:003133030.011
regionalizationGO:00030022740.011
ras protein signal transductionGO:000726570.011
negative regulation of dna replicationGO:000815620.011
nucleotide metabolic processGO:0009117280.011
Human
lymphocyte proliferationGO:004665110.011
regulation of cell cycleGO:0051726520.011
neurotransmitter transportGO:000683620.011
lateral inhibitionGO:004633110.011
Fly
microtubule based movementGO:0007018330.011
maturation of ssu rrnaGO:003049010.011
protein targeting to nucleusGO:004474430.011
dorsal ventral pattern formationGO:00099531250.011
embryonic limb morphogenesisGO:003032620.011
erythrocyte differentiationGO:0030218540.010
regulation of positive chemotaxisGO:005092640.010
regulation of intracellular protein transportGO:003315730.010
nucleoside monophosphate catabolic processGO:000912540.010
Human
camera type eye morphogenesisGO:00485931080.010
cell substrate junction assemblyGO:000704420.010
primitive hemopoiesisGO:0060215270.010
neuron projection morphogenesisGO:00488121610.010

mcm6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
nervous system diseaseDOID:86300.035
muscular diseaseDOID:008000000.024
heart diseaseDOID:11400.024
myopathyDOID:42300.024
musculoskeletal system diseaseDOID:1700.024
cardiovascular system diseaseDOID:128700.024
intrinsic cardiomyopathyDOID:006003600.024
muscle tissue diseaseDOID:6600.024
cardiomyopathyDOID:005070000.024
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
eye and adnexa diseaseDOID:149200.016
sensory system diseaseDOID:005015500.016
eye diseaseDOID:561400.016