Danio rerio

9 known processes

mcm4

MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae)

(Aliases: cb1025,fj85g09,zeh1616,wu:fc12c09,wu:fj85g09,hm:zeh1616,fc12c09)

mcm4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
biosynthetic processGO:00090582940.769
Mouse Fly
heterocycle metabolic processGO:00464832900.704
Human Mouse Fly
cellular macromolecule metabolic processGO:00442603910.603
Human Mouse Fly
cellular aromatic compound metabolic processGO:00067252950.536
Human Mouse Fly
organic cyclic compound metabolic processGO:19013603010.525
Human Mouse Fly
agingGO:000756820.506
larval developmentGO:000216420.495
organic substance biosynthetic processGO:19015762890.495
Mouse Fly
cellular biosynthetic processGO:00442492860.484
Mouse Fly
nucleobase containing compound metabolic processGO:00061392740.481
Human Mouse Fly
regulation of nitrogen compound metabolic processGO:00511712510.435
nucleic acid metabolic processGO:00903042440.431
Human Mouse Fly
regulation of cellular metabolic processGO:00313233200.339
cellular nitrogen compound biosynthetic processGO:00442712180.313
reciprocal meiotic recombinationGO:000713110.293
macromolecule biosynthetic processGO:00090592270.286
Mouse Fly
nucleic acid templated transcriptionGO:00976591810.284
cellular nitrogen compound metabolic processGO:00346412900.278
Human Mouse Fly
heterocycle biosynthetic processGO:00181302150.264
embryo development ending in birth or egg hatchingGO:00097922710.249
regulation of primary metabolic processGO:00800903110.241
regulation of nucleobase containing compound metabolic processGO:00192192500.233
dna biosynthetic processGO:007189730.230
organelle organizationGO:00069962270.221
Fly
regulation of biosynthetic processGO:00098892500.219
organic cyclic compound biosynthetic processGO:19013622230.212
nitrogen compound metabolic processGO:00068073190.211
Human Mouse Fly
rna metabolic processGO:00160702190.209
meiotic chromosome segregationGO:004513230.196
regulation of macromolecule metabolic processGO:00602553170.189
maintenance of dna repeat elementsGO:004357020.175
negative regulation of biological processGO:00485193040.168
regulation of transcription dna templatedGO:00063552130.166
cellular macromolecule biosynthetic processGO:00346452240.165
Mouse Fly
reciprocal dna recombinationGO:003582510.157
regulation of metabolic processGO:00192223590.157
locomotionGO:00400113130.154
single organism biosynthetic processGO:0044711710.145
double strand break repairGO:000630230.145
cell migrationGO:00164772370.142
dna catabolic processGO:000630810.140
response to cadmium ionGO:0046686140.133
aromatic compound biosynthetic processGO:00194382170.132
protein metabolic processGO:00195381830.131
nucleotide biosynthetic processGO:0009165210.112
double strand break repair via homologous recombinationGO:000072410.108
regulation of cellular biosynthetic processGO:00313262450.100
negative regulation of cellular processGO:00485232830.095
regulation of rna metabolic processGO:00512522240.095
single organism metabolic processGO:00447102170.092
Human
double strand break repair via nonhomologous end joiningGO:000630310.092
negative regulation of programmed cell deathGO:0043069580.088
single organism organelle organizationGO:19025891990.084
Fly
camera type eye developmentGO:00430102220.083
rna biosynthetic processGO:00327741810.080
nucleotide metabolic processGO:0009117280.080
Human
transportGO:00068102200.078
sensory organ developmentGO:00074233930.077
response to xenobiotic stimulusGO:0009410450.075
eye developmentGO:00016542770.074
chordate embryonic developmentGO:00430092710.074
mitotic dna integrity checkpointGO:004477440.074
cellular response to chemical stimulusGO:00708871570.072
meiotic cell cycle processGO:190304630.072
cellular response to external stimulusGO:007149620.071
tube morphogenesisGO:00352393490.071
mitotic cell cycleGO:0000278640.070
Fly
regulation of macromolecule biosynthetic processGO:00105562250.067
regulation of nucleic acid templated transcriptionGO:19035062130.065
response to external stimulusGO:00096052640.065
regulation of rna biosynthetic processGO:20011412130.060
dicarboxylic acid metabolic processGO:004364810.057
response to drugGO:004249330.057
transcription dna templatedGO:00063511810.056
gene expressionGO:00104672520.056
cellular component biogenesisGO:00440851780.055
modification dependent protein catabolic processGO:001994130.055
organonitrogen compound metabolic processGO:1901564740.055
Human
carboxylic acid metabolic processGO:0019752220.054
positive regulation of transportGO:005105020.053
response to biotic stimulusGO:0009607970.052
chromosome organizationGO:0051276310.050
dna metabolic processGO:0006259270.050
Human Mouse Fly
cellular response to oxygen containing compoundGO:1901701200.050
meiotic nuclear divisionGO:000712640.049
response to stressGO:00069502630.049
cell surface receptor signaling pathwayGO:00071663250.048
muscle structure developmentGO:00610611960.048
nucleoside monophosphate catabolic processGO:000912540.047
Human
mitotic recombinationGO:000631220.046
pronuclear migrationGO:003504610.046
response to virusGO:0009615210.046
protein acetylationGO:000647320.045
deathGO:00162651210.045
immunoglobulin mediated immune responseGO:001606430.044
wound healingGO:0042060900.044
cytokinesisGO:000091030.044
mitotic dna damage checkpointGO:004477340.044
cellular component movementGO:00069283350.043
fertilizationGO:000956630.043
recombinational repairGO:000072510.043
response to uvGO:000941130.042
nucleobase containing compound biosynthetic processGO:00346542050.042
sensory organ morphogenesisGO:00905962000.041
cellular amino acid metabolic processGO:000652070.040
response to chemicalGO:00422213200.040
regulation of meiotic cell cycleGO:005144510.040
positive regulation of rna metabolic processGO:0051254590.040
cellular macromolecular complex assemblyGO:0034622240.039
positive regulation of cellular processGO:00485222010.038
carbohydrate derivative metabolic processGO:1901135610.038
Human
transcription from rna polymerase ii promoterGO:0006366800.038
regulation of apoptotic processGO:0042981980.038
regulation of cellular ketone metabolic processGO:001056570.037
b cell mediated immunityGO:001972430.037
regulation of protein transportGO:005122330.037
organelle assemblyGO:00709251100.037
meiosis iGO:000712710.037
apoptotic processGO:00069151160.035
amine metabolic processGO:000930820.035
centrosome organizationGO:005129710.035
camera type eye morphogenesisGO:00485931080.034
cell motilityGO:00488702440.034
regulation of dna replicationGO:000627530.034
small molecule metabolic processGO:0044281770.034
Human
regulation of cellular amine metabolic processGO:003323800.033
regulation of gene expressionGO:00104682650.033
g1 s transition of mitotic cell cycleGO:000008210.032
phosphorus metabolic processGO:00067931090.032
Human
regulation of gene expression epigeneticGO:0040029110.031
positive regulation of cellular catabolic processGO:003133130.031
retina morphogenesis in camera type eyeGO:0060042790.031
signal transductionGO:00071654550.031
negative regulation of cell deathGO:0060548600.030
positive regulation of catabolic processGO:000989640.030
regulation of mitotic cell cycleGO:0007346250.030
digestive system developmentGO:00551232890.030
response to organic substanceGO:00100331530.030
retina development in camera type eyeGO:00600411460.030
positive regulation of cell cycleGO:004578730.030
negative regulation of dna recombinationGO:004591020.029
proteolysis involved in cellular protein catabolic processGO:005160330.029
cell fate commitmentGO:0045165990.029
localization of cellGO:00516742440.028
cellular amine metabolic processGO:004410620.028
response to organic cyclic compoundGO:0014070510.028
positive regulation of cellular metabolic processGO:0031325940.028
negative regulation of chromosome organizationGO:200125110.028
phosphate containing compound metabolic processGO:00067961080.027
Human
negative regulation of histone modificationGO:003105710.027
positive regulation of nuclease activityGO:003207510.027
immunoglobulin productionGO:000237710.027
cellular protein modification processGO:00064641000.027
muscle organ developmentGO:00075171010.027
digestive tract developmentGO:00485652650.027
positive regulation of rna biosynthetic processGO:1902680570.026
regulation of cell deathGO:00109411030.026
b cell activationGO:004211320.026
regulation of cellular amino acid metabolic processGO:000652100.026
regulation of cellular macromolecule biosynthetic processGO:20001122220.026
negative regulation of apoptotic processGO:0043066550.026
cell deathGO:00082191210.026
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.026
oxoacid metabolic processGO:0043436310.025
urogenital system developmentGO:0001655970.025
microtubule polymerizationGO:004678520.025
muscle cell differentiationGO:00426921390.025
positive regulation of nitrogen compound metabolic processGO:0051173690.025
negative regulation of cellular metabolic processGO:0031324770.024
centrosome cycleGO:000709810.024
somatic cell dna recombinationGO:001644410.024
maintenance of locationGO:005123540.024
negative regulation of nitrogen compound metabolic processGO:0051172590.024
proteasomal protein catabolic processGO:001049820.024
proteolysisGO:0006508380.024
regulation of cell cycleGO:0051726520.024
cellular response to organic substanceGO:00713101050.024
response to endogenous stimulusGO:0009719830.024
positive regulation of macromolecule biosynthetic processGO:0010557590.023
regulation of peptidase activityGO:0052547230.023
positive regulation of lymphocyte mediated immunityGO:000270810.023
purine nucleoside monophosphate catabolic processGO:000912840.023
Human
centrosome duplicationGO:005129810.022
cellular ketone metabolic processGO:0042180110.022
multicellular organism growthGO:003526440.022
regulation of nuclease activityGO:003206910.022
cellular protein metabolic processGO:00442671290.022
macromolecular complex assemblyGO:0065003350.022
positive regulation of chromosome segregationGO:005198410.022
male meiosisGO:000714020.022
macromolecule methylationGO:0043414190.022
pancreas developmentGO:0031016840.021
response to metal ionGO:0010038340.021
cell cycleGO:0007049930.021
Fly
organic acid metabolic processGO:0006082310.021
positive regulation of chromatin modificationGO:190331010.021
mitotic metaphase plate congressionGO:000708010.021
negative regulation of biosynthetic processGO:0009890550.021
negative regulation of gene expressionGO:0010629650.021
nuclear migrationGO:000709730.021
cellular response to organic cyclic compoundGO:0071407380.020
determination of heart left right asymmetryGO:00613711170.020
regulation of cellular component organizationGO:0051128860.020
establishment of localizationGO:00512342440.020
negative regulation of macromolecule metabolic processGO:0010605760.020
cell morphogenesisGO:00009022890.020
cell cycle g1 s phase transitionGO:004484310.020
regulation of deoxyribonuclease activityGO:003207010.020
response to lipidGO:0033993600.020
nucleobase containing small molecule metabolic processGO:0055086320.019
Human
dna alkylationGO:000630580.019
zymogen activationGO:003163830.019
production of molecular mediator of immune responseGO:000244020.019
heart contractionGO:0060047710.019
positive regulation of immune effector processGO:000269930.019
response to steroid hormoneGO:0048545350.019
organophosphate metabolic processGO:0019637370.019
Human
macromolecular complex subunit organizationGO:0043933740.019
Fly
gene silencingGO:001645840.019
deoxyribonucleotide biosynthetic processGO:000926310.019
negative regulation of metabolic processGO:0009892860.019
embryonic organ developmentGO:00485683810.019
vasculature developmentGO:00019442780.019
immune system processGO:00023762410.018
single organism localizationGO:19025782250.018
muscle cell developmentGO:00550011150.018
regulation of dna recombinationGO:000001820.018
regulation of dna catabolic processGO:190362410.018
cell proliferationGO:0008283800.018
programmed cell deathGO:00125011190.018
skeletal system developmentGO:00015011810.018
regulation of protein metabolic processGO:0051246560.018
regulation of establishment of protein localizationGO:007020140.018
regulation of leukocyte mediated immunityGO:000270310.018
ubiquitin dependent protein catabolic processGO:000651130.018
intracellular signal transductionGO:0035556850.017
positive regulation of macromolecule metabolic processGO:0010604930.017
chromatin organizationGO:0006325220.017
cell part morphogenesisGO:00329902460.017
negative regulation of cellular biosynthetic processGO:0031327550.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of catalytic activityGO:0050790550.017
negative regulation of rna metabolic processGO:0051253480.017
response to amino acidGO:004320020.017
regulation of apoptotic signaling pathwayGO:2001233120.016
non recombinational repairGO:000072620.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.016
regulation of programmed cell deathGO:00430671010.016
negative regulation of dna metabolic processGO:005105340.016
heart processGO:0003015710.016
heart loopingGO:0001947940.016
ion transportGO:00068111140.016
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.016
determination of bilateral symmetryGO:00098552040.016
lipid homeostasisGO:005508830.016
reproductionGO:0000003400.016
peptidyl serine phosphorylationGO:001810510.016
dna methylation on cytosineGO:003277630.016
striated muscle cell developmentGO:00550021080.016
lipid storageGO:001991510.016
negative regulation of mitotic cell cycle phase transitionGO:190199150.016
myofibril assemblyGO:0030239480.016
response to external biotic stimulusGO:0043207970.015
embryonic digestive tract morphogenesisGO:004855730.015
circulatory system processGO:0003013870.015
cellular response to oxygen levelsGO:007145310.015
g2 m transition of mitotic cell cycleGO:000008640.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
negative regulation of cellular catabolic processGO:003133030.015
multi organism processGO:00517041340.015
regulation of proteolysisGO:0030162240.015
regulation of transcription from rna polymerase ii promoterGO:00063571140.015
positive regulation of leukocyte mediated immunityGO:000270510.015
peptidyl serine modificationGO:001820920.014
regulation of cysteine type endopeptidase activityGO:2000116210.014
purine containing compound metabolic processGO:0072521290.014
Human
regulation of response to stimulusGO:00485832690.014
regulation of endopeptidase activityGO:0052548230.014
protein modification processGO:00362111000.014
ribonucleoside monophosphate catabolic processGO:000915840.014
Human
pyrimidine containing compound biosynthetic processGO:007252820.014
microtubule based processGO:0007017600.013
Fly
brain developmentGO:00074202930.013
negative regulation of rna biosynthetic processGO:1902679450.013
positive regulation of gene expressionGO:0010628710.013
cartilage developmentGO:0051216960.013
positive regulation of biosynthetic processGO:0009891680.013
developmental process involved in reproductionGO:0003006270.013
protein acylationGO:004354330.013
cell projection organizationGO:00300302840.013
regulation of intracellular protein transportGO:003315730.013
response to ethanolGO:004547160.013
negative regulation of gene silencingGO:006096910.013
positive regulation of biological processGO:00485182530.013
regulation of multicellular organism growthGO:004001440.013
embryonic neurocranium morphogenesisGO:0048702150.013
nucleoside phosphate biosynthetic processGO:1901293210.013
phosphorylationGO:0016310690.013
exocrine pancreas developmentGO:0031017280.013
cellular component assemblyGO:00226071700.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
positive regulation of metabolic processGO:00098931080.013
meiotic spindle organizationGO:000021210.013
regulation of carbohydrate metabolic processGO:000610940.013
guanosine containing compound metabolic processGO:190106840.013
metal ion transportGO:0030001580.013
regulation of nucleocytoplasmic transportGO:004682220.013
guanosine containing compound catabolic processGO:190106920.012
negative regulation of nucleobase containing compound metabolic processGO:0045934590.012
negative regulation of histone methylationGO:003106110.012
blood vessel developmentGO:00015682460.012
negative regulation of transcription dna templatedGO:0045892450.012
positive regulation of histone modificationGO:003105810.012
negative regulation of cell communicationGO:0010648960.012
regulation of hydrolase activityGO:0051336280.012
regulation of chromosome segregationGO:005198310.012
internal peptidyl lysine acetylationGO:001839320.012
response to inorganic substanceGO:0010035380.012
chromosome organization involved in meiosisGO:007019210.012
negative regulation of protein phosphorylationGO:000193340.012
histone methylationGO:0016571130.012
negative regulation of protein kinase activityGO:000646940.012
epithelial cell differentiationGO:00308551160.012
regulation of cytoplasmic transportGO:190364940.012
cellular localizationGO:0051641970.012
response to alkaloidGO:004327920.012
nucleoside phosphate metabolic processGO:0006753280.011
Human
single fertilizationGO:000733830.011
internal protein amino acid acetylationGO:000647520.011
regulation of protein catabolic processGO:004217610.011
negative regulation of macromolecule biosynthetic processGO:0010558480.011
protein polymerizationGO:005125840.011
regulation of protein ubiquitinationGO:003139630.011
regulation of biological qualityGO:00650082630.011
cytoskeleton organizationGO:0007010960.011
Fly
peptidyl lysine acetylationGO:001839420.011
response to corticosteroidGO:003196010.011
monovalent inorganic cation transportGO:0015672420.011
regulation of dna methylationGO:004403050.011
establishment of protein localization to organelleGO:007259440.011
protein complex biogenesisGO:0070271300.011
negative regulation of signal transductionGO:0009968940.011
protein complex assemblyGO:0006461300.011
positive regulation of striated muscle tissue developmentGO:004584410.011
negative regulation of cell divisionGO:005178240.011
embryonic organ morphogenesisGO:00485622740.011
posttranscriptional gene silencing by rnaGO:003519430.011
hematopoietic or lymphoid organ developmentGO:00485341910.010
spindle assemblyGO:005122520.010
protein phosphorylationGO:0006468470.010
stem cell maintenanceGO:001982740.010
negative regulation of signalingGO:0023057960.010
regulation of circadian rhythmGO:004275240.010
rna transportGO:005065820.010
immune system developmentGO:00025201910.010
positive regulation of muscle tissue developmentGO:190186310.010
response to nitrogen compoundGO:1901698190.010
protein importGO:001703830.010

mcm4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
developmental disorder of mental healthDOID:006003700.031
disease of mental healthDOID:15000.031
disease of metabolismDOID:001466700.024
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.018
disease of anatomical entityDOID:700.015
intestinal cancerDOID:1015500.014
gastrointestinal system cancerDOID:311900.014
organ system cancerDOID:005068600.014
colorectal cancerDOID:925600.014
large intestine cancerDOID:567200.014