Danio rerio

0 known processes

clu

clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)

(Aliases: MGC73352,zgc:73352)

clu biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cognitionGO:005089010.279
central nervous system developmentGO:00074173870.269
Human
response to abiotic stimulusGO:00096281220.165
embryonic organ morphogenesisGO:00485622740.132
regulation of multicellular organismal processGO:00512392770.126
Human
embryonic organ developmentGO:00485683810.126
positive regulation of cell deathGO:0010942290.116
Human Mouse
regulation of nitrogen compound metabolic processGO:00511712510.114
Human Mouse
chordate embryonic developmentGO:00430092710.103
regulation of cell communicationGO:00106462320.102
Human
regulation of response to stimulusGO:00485832690.098
Human
skeletal system morphogenesisGO:00487051020.091
embryonic skeletal system developmentGO:0048706970.089
regulation of signalingGO:00230512350.087
Human
system processGO:00030081850.085
regulation of signal transductionGO:00099662250.082
Human
programmed cell deathGO:00125011190.081
Human
response to hexoseGO:000974630.079
response to carbohydrateGO:000974330.078
small molecule metabolic processGO:0044281770.078
skeletal system developmentGO:00015011810.076
cellular response to external stimulusGO:007149620.075
single organism localizationGO:19025782250.073
Human
positive regulation of apoptotic processGO:0043065290.072
Human
embryonic skeletal system morphogenesisGO:0048704930.072
embryo development ending in birth or egg hatchingGO:00097922710.070
response to monosaccharideGO:003428430.068
apoptotic processGO:00069151160.068
Human
regulation of cellular metabolic processGO:00313233200.067
Human Mouse
response to drugGO:004249330.064
response to corticosteroidGO:003196010.064
deathGO:00162651210.063
Human Mouse
response to glucoseGO:000974930.060
regulation of cell deathGO:00109411030.060
Human Mouse
response to glucocorticoidGO:005138410.058
regulation of cellular component organizationGO:0051128860.056
Human
organonitrogen compound metabolic processGO:1901564740.056
Human Mouse
regulation of muscle contractionGO:000693730.055
cellular nitrogen compound metabolic processGO:00346412900.055
Human Mouse
eye morphogenesisGO:00485921440.055
organic acid metabolic processGO:0006082310.054
regulation of programmed cell deathGO:00430671010.054
Human
negative regulation of cellular processGO:00485232830.052
Human
amine metabolic processGO:000930820.052
blood vessel morphogenesisGO:00485142160.049
regulation of developmental processGO:00507932470.048
response to chemicalGO:00422213200.048
Human
cellular component morphogenesisGO:00329893360.048
Human
regulation of primary metabolic processGO:00800903110.048
Human Mouse
regulation of apoptotic processGO:0042981980.048
Human
positive regulation of blood circulationGO:190352420.047
astrocyte differentiationGO:004870810.047
cellular carbohydrate metabolic processGO:004426240.047
negative regulation of biological processGO:00485193040.047
Human
regulation of gtp catabolic processGO:003312420.044
cellular amine metabolic processGO:004410620.043
positive regulation of i kappab kinase nf kappab signalingGO:004312330.043
collagen metabolic processGO:003296320.043
positive regulation of catabolic processGO:000989640.042
Human
cell surface receptor signaling pathwayGO:00071663250.042
response to amino acidGO:004320020.042
cell deathGO:00082191210.041
Human Mouse
maternal determination of anterior posterior axis embryoGO:000835840.041
regulation of metabolic processGO:00192223590.040
Human Mouse
intracellular signal transductionGO:0035556850.039
Human
generation of neuronsGO:00486993850.039
cellular response to chemical stimulusGO:00708871570.038
vasculature developmentGO:00019442780.038
regulation of cellular amine metabolic processGO:003323800.037
meiotic nuclear divisionGO:000712640.036
agingGO:000756820.036
regulation of cellular amino acid metabolic processGO:000652100.036
regulation of metal ion transportGO:001095940.035
multicellular organismal macromolecule metabolic processGO:004425920.035
circulatory system processGO:0003013870.035
regulation of cell shapeGO:000836010.033
head developmentGO:00603223030.033
signal transductionGO:00071654550.033
Human
carbohydrate derivative metabolic processGO:1901135610.032
response to nutrientGO:000758430.032
specification of symmetryGO:00097992040.032
growthGO:00400071740.032
brain developmentGO:00074202930.032
oxoacid metabolic processGO:0043436310.032
cell migrationGO:00164772370.032
regulation of multicellular organismal developmentGO:20000262230.031
cellular response to nutrient levelsGO:003166920.031
blood circulationGO:0008015870.031
organic cyclic compound biosynthetic processGO:19013622230.031
Human
morphogenesis of an epitheliumGO:00020093330.030
regulation of i kappab kinase nf kappab signalingGO:004312240.029
gene expressionGO:00104672520.029
Human
larval developmentGO:000216420.029
positive regulation of cellular catabolic processGO:003133130.029
Human
maintenance of locationGO:005123540.028
response to lipidGO:0033993600.028
cellular amino acid metabolic processGO:000652070.028
mitochondrion organizationGO:000700540.028
establishment of localizationGO:00512342440.028
Human
embryonic cranial skeleton morphogenesisGO:0048701900.027
regulation of skeletal muscle tissue developmentGO:004864140.027
regulation of bindingGO:005109830.027
cellular response to hypoxiaGO:007145610.027
response to organic substanceGO:00100331530.027
Human
cellular response to oxygen levelsGO:007145310.027
regulation of purine nucleotide catabolic processGO:003312120.026
macromolecule biosynthetic processGO:00090592270.026
Human
regulation of reproductive processGO:200024140.026
regulation of blood pressureGO:000821710.026
macromolecular complex assemblyGO:0065003350.026
Human
single organism metabolic processGO:00447102170.026
cellular response to decreased oxygen levelsGO:003629410.026
regulation of synaptic plasticityGO:004816710.025
positive regulation of transportGO:005105020.025
regulation of nucleoside metabolic processGO:000911820.025
meiotic cell cycle processGO:190304630.025
response to vitaminGO:003327330.025
cellular biosynthetic processGO:00442492860.025
Human
regulation of reactive oxygen species metabolic processGO:200037720.024
regulation of nucleotide catabolic processGO:003081120.024
positive regulation of cellular component biogenesisGO:004408930.024
Human
mesenchyme developmentGO:00604851270.024
regulation of cellular ketone metabolic processGO:001056570.023
response to transition metal nanoparticleGO:1990267280.023
oocyte anterior posterior axis specificationGO:000731440.023
protein polymerizationGO:005125840.023
mesenchymal cell differentiationGO:0048762870.023
embryonic skeletal joint morphogenesisGO:006027230.022
regulation of nucleic acid templated transcriptionGO:19035062130.022
Human
regulation of cell activationGO:005086510.022
regulation of system processGO:0044057400.022
response to oxygen levelsGO:0070482250.022
neurological system processGO:0050877620.022
epithelial tube morphogenesisGO:00605621480.022
transmembrane transportGO:00550851200.021
negative regulation of signalingGO:0023057960.021
Human
cell projection organizationGO:00300302840.021
cytokinesisGO:000091030.021
behaviorGO:0007610740.021
multicellular organismal metabolic processGO:004423620.021
blood vessel developmentGO:00015682460.021
biosynthetic processGO:00090582940.021
Human
multicellular organism growthGO:003526440.020
regulation of tube sizeGO:003515020.020
b cell activationGO:004211320.020
response to organic cyclic compoundGO:0014070510.020
neuron developmentGO:00486662620.020
cellular response to extracellular stimulusGO:003166820.020
cellular response to starvationGO:000926710.020
positive regulation of cellular amino acid metabolic processGO:004576400.020
response to decreased oxygen levelsGO:0036293250.020
regulation of sodium ion transportGO:000202820.020
sympathetic nervous system developmentGO:004848530.020
nucleobase containing compound biosynthetic processGO:00346542050.020
Human
regulation of cell differentiationGO:00455951420.020
protein localization to nucleusGO:003450430.019
macromolecule modificationGO:00434121110.019
Human
positive regulation of purine nucleotide catabolic processGO:003312310.019
heterocycle metabolic processGO:00464832900.019
Human
carboxylic acid metabolic processGO:0019752220.019
protein heterooligomerizationGO:005129110.019
regulation of biosynthetic processGO:00098892500.019
Human
regulation of nucleobase containing compound metabolic processGO:00192192500.019
Human
regulation of cellular biosynthetic processGO:00313262450.019
Human
neuron neuron synaptic transmissionGO:000727010.019
organelle organizationGO:00069962270.019
response to hormoneGO:0009725480.018
branching morphogenesis of a nerveGO:004875540.018
protein importGO:001703830.018
Human
regulation of cell migrationGO:0030334400.018
cytoplasm organizationGO:000702840.018
regulation of cytoplasmic transportGO:190364940.018
regulation of nucleotide metabolic processGO:0006140170.018
response to endogenous stimulusGO:0009719830.018
nitrogen compound metabolic processGO:00068073190.018
Human Mouse
muscle organ developmentGO:00075171010.018
organic substance biosynthetic processGO:19015762890.018
Human
embryonic heart tube morphogenesisGO:00031431080.018
regulation of blood vessel sizeGO:005088020.018
regulation of transmembrane transporter activityGO:002289820.018
regulation of wound healingGO:006104120.017
positive regulation of protein kinase b signalingGO:005189710.017
cytoskeleton dependent cytokinesisGO:006164030.017
positive regulation of cytokine productionGO:000181920.017
Human
negative regulation of protein phosphorylationGO:000193340.017
regulation of catalytic activityGO:0050790550.017
Human
cation transmembrane transportGO:0098655650.017
response to alkaloidGO:004327920.017
cell morphogenesisGO:00009022890.017
Human
cellular aromatic compound metabolic processGO:00067252950.017
Human
regulation of inflammatory responseGO:005072720.017
carbon dioxide transportGO:001567030.017
regulation of cell developmentGO:00602841000.017
regulation of response to external stimulusGO:0032101310.017
notochord developmentGO:0030903540.017
carbohydrate homeostasisGO:003350010.017
positive regulation of cellular amine metabolic processGO:003324000.017
cellular aldehyde metabolic processGO:000608140.017
gtp metabolic processGO:004603940.016
phagocytosisGO:000690930.016
embryonic skeletal joint developmentGO:007249830.016
regulation of protein metabolic processGO:0051246560.016
Human Mouse
regulation of gene expressionGO:00104682650.016
Human
cellular response to stressGO:0033554620.016
Human
camera type eye developmentGO:00430102220.016
cellular macromolecule metabolic processGO:00442603910.016
Human
regulation of cellular carbohydrate metabolic processGO:001067540.016
response to stressGO:00069502630.016
Human
purine ribonucleoside monophosphate catabolic processGO:000916940.016
rna metabolic processGO:00160702190.016
Human
determination of heart left right asymmetryGO:00613711170.016
meiotic chromosome segregationGO:004513230.016
positive regulation of heart contractionGO:004582320.015
regulation of gtpase activityGO:004308720.015
membrane fusionGO:006102520.015
central nervous system myelinationGO:002201020.015
Human
pole plasm assemblyGO:000731540.015
energy reserve metabolic processGO:000611220.015
multi organism processGO:00517041340.015
Human
neural crest cell differentiationGO:0014033720.015
positive regulation of biological processGO:00485182530.015
Human Mouse
neurotransmitter transportGO:000683620.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.015
regulation of carbohydrate metabolic processGO:000610940.015
endocrine processGO:005088620.015
organelle fusionGO:004828430.015
cell cycle arrestGO:000705010.015
nuclear transportGO:005116940.015
intracellular mrna localizationGO:000829810.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
reactive nitrogen species metabolic processGO:200105700.015
i kappab kinase nf kappab signalingGO:000724940.015
positive regulation of lipid metabolic processGO:004583410.015
positive regulation of cell activationGO:005086710.014
atp catabolic processGO:000620040.014
nucleoside monophosphate catabolic processGO:000912540.014
adult behaviorGO:003053420.014
regulation of ion transmembrane transporter activityGO:003241220.014
retina development in camera type eyeGO:00600411460.014
rna localizationGO:000640340.014
sequestering of metal ionGO:005123830.014
guanosine containing compound metabolic processGO:190106840.014
ras protein signal transductionGO:000726570.014
smooth muscle contractionGO:000693920.014
gtp catabolic processGO:000618420.014
positive regulation of nucleotide catabolic processGO:003081310.014
regulation of neuronal synaptic plasticityGO:004816810.014
response to uvGO:000941130.014
connective tissue developmentGO:0061448990.014
response to xenobiotic stimulusGO:0009410450.014
localization of cellGO:00516742440.014
guanosine containing compound catabolic processGO:190106920.014
transportGO:00068102200.014
Human
ion transportGO:00068111140.014
response to mechanical stimulusGO:0009612240.013
neuron differentiationGO:00301823530.013
phosphorylationGO:0016310690.013
Human
regulation of oocyte developmentGO:006028130.013
regulation of multicellular organism growthGO:004001440.013
regulation of protein complex assemblyGO:004325430.013
Human
regulation of molecular functionGO:0065009700.013
Human
long chain fatty acid metabolic processGO:000167610.013
regulation of cell morphogenesis involved in differentiationGO:0010769380.013
single organism membrane fusionGO:004480120.013
tube morphogenesisGO:00352393490.013
sleepGO:003043110.013
cellular component disassemblyGO:002241110.013
macromolecule localizationGO:0033036540.013
Human
gliogenesisGO:0042063450.013
Human
cell growthGO:0016049570.013
positive regulation of cytoskeleton organizationGO:005149530.013
nerve developmentGO:0021675450.013
single organism transportGO:00447652060.013
Human
regulation of protein transportGO:005122330.013
olfactory bulb developmentGO:002177240.013
regulation of receptor activityGO:001046920.013
cellular component assemblyGO:00226071700.013
Human
proteolysis involved in cellular protein catabolic processGO:005160330.013
Human
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
regulation of biological qualityGO:00650082630.012
Human
negative regulation of macromolecule metabolic processGO:0010605760.012
Human
extrinsic apoptotic signaling pathwayGO:009719130.012
regulation of cellular component movementGO:0051270550.012
regulation of ras gtpase activityGO:003231820.012
glucose importGO:004632320.012
regulation of rna metabolic processGO:00512522240.012
Human
cytosolic calcium ion transportGO:006040130.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
positive regulation of metabolic processGO:00098931080.012
Human Mouse
heterocycle biosynthetic processGO:00181302150.012
Human
trabecula formationGO:006034320.012
hormone secretionGO:004687920.012
gas transportGO:001566930.012
protein localization to plasma membraneGO:007265910.012
organelle assemblyGO:00709251100.012
positive regulation of gene expressionGO:0010628710.012
fatty acid transportGO:001590810.012
hindbrain developmentGO:0030902910.012
regulation of calcium ion transportGO:005192420.012
cellular protein modification processGO:00064641000.012
Human
purine nucleotide metabolic processGO:0006163270.012
monoamine transportGO:001584410.011
positive regulation of immune effector processGO:000269930.011
positive regulation of gtp catabolic processGO:003312610.011
heart contractionGO:0060047710.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
nucleic acid templated transcriptionGO:00976591810.011
Human
single organism biosynthetic processGO:0044711710.011
locomotionGO:00400113130.011
protein metabolic processGO:00195381830.011
Human Mouse
nucleocytoplasmic transportGO:000691340.011
synaptic vesicle recyclingGO:003646510.011
mitotic cytokinesisGO:000028130.011
negative regulation of dna metabolic processGO:005105340.011
anterior posterior pattern specificationGO:00099521520.011
establishment of protein localization to organelleGO:007259440.011
positive regulation of cell cycleGO:004578730.011
synaptic vesicle endocytosisGO:004848810.011
camera type eye morphogenesisGO:00485931080.011
regulation of transporter activityGO:003240920.011
cellular protein metabolic processGO:00442671290.011
Human
stem cell proliferationGO:007208940.011
lymph vessel developmentGO:0001945270.011
regulation of systemic arterial blood pressureGO:000307310.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
Human
cell matrix adhesionGO:000716040.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
Human
mononuclear cell proliferationGO:003294310.011
regulation of cytokine productionGO:000181730.011
Human
response to oxygen containing compoundGO:1901700550.010
regulation of dendrite morphogenesisGO:004881430.010
regulation of dendrite developmentGO:005077330.010
skeletal muscle organ developmentGO:0060538780.010
positive regulation of gtpase activityGO:004354710.010
regulation of phGO:000688530.010
type b pancreatic cell proliferationGO:004434210.010
cellular localizationGO:0051641970.010
immune system developmentGO:00025201910.010
positive regulation of signal transductionGO:0009967560.010
Human
carbohydrate biosynthetic processGO:001605110.010
negative regulation of map kinase activityGO:004340720.010
negative regulation of developmental processGO:0051093650.010
heart processGO:0003015710.010
axis specificationGO:0009798430.010
positive regulation of nucleoside metabolic processGO:004597910.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.010
cellular response to retinoic acidGO:007130010.010
lateral line system developmentGO:0048925760.010
response to estrogenGO:0043627270.010
neuron projection morphogenesisGO:00488121610.010
actin filament polymerizationGO:003004120.010
peptidyl serine modificationGO:001820920.010
cellular protein catabolic processGO:004425740.010
Human
interspecies interaction between organismsGO:004441940.010
establishment of protein localization to plasma membraneGO:009000210.010

clu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
musculoskeletal system diseaseDOID:1700.013
connective tissue diseaseDOID:6500.013
charcot marie tooth disease type 4DOID:005054100.011
neuropathyDOID:87000.011
nervous system diseaseDOID:86300.011
charcot marie tooth diseaseDOID:1059500.011
neuromuscular diseaseDOID:44000.011
organ system cancerDOID:005068600.010
cancerDOID:16200.010
disease of cellular proliferationDOID:1456600.010