Danio rerio

0 known processes

fbxw2

F-box and WD repeat domain containing 2

(Aliases: wu:fc72f10,zgc:110365)

fbxw2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
modification dependent protein catabolic processGO:001994130.292
cellular protein catabolic processGO:004425740.260
agingGO:000756820.219
modification dependent macromolecule catabolic processGO:004363230.206
proteolysis involved in cellular protein catabolic processGO:005160330.186
single organism metabolic processGO:00447102170.134
cellular macromolecule metabolic processGO:00442603910.102
regulation of metabolic processGO:00192223590.099
establishment of protein localization to organelleGO:007259440.098
ubiquitin dependent protein catabolic processGO:000651130.096
macromolecule biosynthetic processGO:00090592270.091
protein metabolic processGO:00195381830.090
cellular protein metabolic processGO:00442671290.082
nitrogen compound metabolic processGO:00068073190.078
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.076
negative regulation of biological processGO:00485193040.076
positive regulation of cell cycleGO:004578730.073
organic substance biosynthetic processGO:19015762890.073
regulation of cellular metabolic processGO:00313233200.072
negative regulation of cellular processGO:00485232830.072
cellular nitrogen compound biosynthetic processGO:00442712180.069
signal transductionGO:00071654550.062
nucleocytoplasmic transportGO:000691340.062
phosphorus metabolic processGO:00067931090.060
proteasomal protein catabolic processGO:001049820.058
extrinsic apoptotic signaling pathwayGO:009719130.058
single organism nuclear importGO:190259330.057
cellular response to organic substanceGO:00713101050.056
cell surface receptor signaling pathwayGO:00071663250.055
establishment of localizationGO:00512342440.054
cell deathGO:00082191210.054
cellular component movementGO:00069283350.053
protein modification processGO:00362111000.053
larval developmentGO:000216420.053
phagocytosisGO:000690930.053
nucleic acid metabolic processGO:00903042440.053
protein localization to nucleusGO:003450430.053
nuclear transportGO:005116940.052
apoptotic processGO:00069151160.052
cellular response to nutrient levelsGO:003166920.050
protein targeting to nucleusGO:004474430.048
negative regulation of catabolic processGO:000989530.048
organic cyclic compound biosynthetic processGO:19013622230.046
mitochondrion organizationGO:000700540.046
mitotic dna damage checkpointGO:004477340.045
cellular biosynthetic processGO:00442492860.044
peptidyl serine phosphorylationGO:001810510.044
single organism organelle organizationGO:19025891990.043
cellular protein modification processGO:00064641000.043
nuclear importGO:005117030.042
mitotic g2 m transition checkpointGO:004481830.042
mitotic dna integrity checkpointGO:004477440.042
organic cyclic compound metabolic processGO:19013603010.042
cellular amino acid metabolic processGO:000652070.041
positive regulation of transportGO:005105020.041
regulation of cellular amino acid metabolic processGO:000652100.041
organelle organizationGO:00069962270.041
regulation of establishment of protein localizationGO:007020140.041
cellular macromolecule biosynthetic processGO:00346452240.040
autophagyGO:000691440.039
locomotor rhythmGO:004547530.039
response to chemicalGO:00422213200.039
phagocytosis engulfmentGO:000691110.039
nucleic acid templated transcriptionGO:00976591810.037
cell projection morphogenesisGO:00488582440.037
negative regulation of metabolic processGO:0009892860.037
negative regulation of protein kinase activityGO:000646940.037
cellular carbohydrate metabolic processGO:004426240.037
establishment of protein localization to plasma membraneGO:009000210.037
maintenance of locationGO:005123540.037
membrane lipid biosynthetic processGO:004646720.037
regulation of protein ubiquitinationGO:003139630.036
transportGO:00068102200.036
g2 dna damage checkpointGO:003157230.036
amine metabolic processGO:000930820.036
regulation of protein localization to nucleusGO:190018020.036
stem cell maintenanceGO:001982740.036
enzyme linked receptor protein signaling pathwayGO:00071671060.036
gene expressionGO:00104672520.036
microtubule organizing center organizationGO:003102310.036
sensory organ developmentGO:00074233930.036
response to stressGO:00069502630.035
cellular response to extracellular stimulusGO:003166820.035
regulation of biosynthetic processGO:00098892500.035
negative regulation of kinase activityGO:003367340.035
regulation of macromolecule metabolic processGO:00602553170.035
blood vessel developmentGO:00015682460.035
cognitionGO:005089010.035
positive regulation of biological processGO:00485182530.034
regulation of macromolecule biosynthetic processGO:00105562250.034
protein importGO:001703830.034
regulation of protein transportGO:005122330.034
negative regulation of mapk cascadeGO:004340940.034
stem cell proliferationGO:007208940.034
regulation of synaptic plasticityGO:004816710.034
adult behaviorGO:003053420.034
protein polyubiquitinationGO:000020940.033
negative regulation of protein phosphorylationGO:000193340.033
single organism transportGO:00447652060.033
regulation of nitrogen compound metabolic processGO:00511712510.033
regionalizationGO:00030022740.033
biosynthetic processGO:00090582940.033
cellular nitrogen compound metabolic processGO:00346412900.032
regulation of primary metabolic processGO:00800903110.032
heterocycle metabolic processGO:00464832900.032
cell morphogenesisGO:00009022890.032
regulation of signal transductionGO:00099662250.032
cellular amine metabolic processGO:004410620.031
cell migrationGO:00164772370.031
regulation of stem cell proliferationGO:007209120.031
system processGO:00030081850.031
regulation of cytoplasmic transportGO:190364940.031
protein dephosphorylationGO:000647030.031
centrosome cycleGO:000709810.030
rna metabolic processGO:00160702190.030
cellular response to external stimulusGO:007149620.030
vasculature developmentGO:00019442780.030
regulation of protein modification by small protein conjugation or removalGO:190332030.030
peptidyl serine modificationGO:001820920.030
peptide transportGO:001583310.030
regulation of biological qualityGO:00650082630.030
cellular response to chemical stimulusGO:00708871570.029
protein import into nucleusGO:000660630.029
regulation of cellular ketone metabolic processGO:001056570.029
single organism biosynthetic processGO:0044711710.029
membrane invaginationGO:001032410.028
organic acid metabolic processGO:0006082310.028
blood vessel morphogenesisGO:00485142160.028
protein heterooligomerizationGO:005129110.028
lateral inhibitionGO:004633110.027
phosphate containing compound metabolic processGO:00067961080.027
regulation of circadian rhythmGO:004275240.027
immune system developmentGO:00025201910.027
mitotic g2 dna damage checkpointGO:000709530.027
regulation of gene expressionGO:00104682650.027
cellular ketone metabolic processGO:0042180110.027
macromolecule modificationGO:00434121110.026
regulation of organelle assemblyGO:190211540.026
tube morphogenesisGO:00352393490.026
muscle organ developmentGO:00075171010.026
regulation of protein catabolic processGO:004217610.026
cellular aromatic compound metabolic processGO:00067252950.026
regulation of signalingGO:00230512350.025
regulation of response to stimulusGO:00485832690.025
organonitrogen compound metabolic processGO:1901564740.025
cytokinesisGO:000091030.025
regulation of transcription dna templatedGO:00063552130.025
oxoacid metabolic processGO:0043436310.025
compound eye developmentGO:004874920.025
rna localizationGO:000640340.025
negative regulation of macromolecule metabolic processGO:0010605760.025
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.025
cellular response to stressGO:0033554620.025
cellular component morphogenesisGO:00329893360.024
regulation of developmental processGO:00507932470.024
cell substrate adhesionGO:003158940.024
stem cell divisionGO:001714510.024
rna biosynthetic processGO:00327741810.024
regulation of apoptotic processGO:0042981980.023
transcription dna templatedGO:00063511810.023
pyruvate metabolic processGO:000609010.023
cellular component biogenesisGO:00440851780.023
regulation of intracellular protein transportGO:003315730.023
negative regulation of response to stimulusGO:00485851040.023
cell projection organizationGO:00300302840.023
single organism localizationGO:19025782250.023
regulation of cellular macromolecule biosynthetic processGO:20001122220.023
regulation of cellular amine metabolic processGO:003323800.023
regulation of cell communicationGO:00106462320.022
germ line stem cell maintenanceGO:003071820.022
morphogenesis of an epitheliumGO:00020093330.022
phosphorylationGO:0016310690.022
multicellular organism growthGO:003526440.022
regulation of reproductive processGO:200024140.022
neuron projection morphogenesisGO:00488121610.022
generation of neuronsGO:00486993850.022
neuron differentiationGO:00301823530.022
positive regulation of i kappab kinase nf kappab signalingGO:004312330.022
positive regulation of catabolic processGO:000989640.021
negative regulation of protein transportGO:005122430.021
neuron projection developmentGO:00311751800.021
negative regulation of cell cycle processGO:001094890.021
digestive tract developmentGO:00485652650.021
negative regulation of signalingGO:0023057960.021
locomotionGO:00400113130.021
regulation of meiotic cell cycleGO:005144510.020
regulation of extrinsic apoptotic signaling pathwayGO:200123630.020
positive regulation of jnk cascadeGO:004633030.020
response to organic substanceGO:00100331530.020
convergent extensionGO:00600261180.020
regulation of protein metabolic processGO:0051246560.020
deathGO:00162651210.020
small molecule metabolic processGO:0044281770.020
positive regulation of cellular amino acid metabolic processGO:004576400.020
regulation of nucleocytoplasmic transportGO:004682220.020
regulation of rna biosynthetic processGO:20011412130.020
protein localization to plasma membraneGO:007265910.019
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
hormone transportGO:000991420.019
erk1 and erk2 cascadeGO:007037140.019
neuron developmentGO:00486662620.019
positive regulation of apoptotic signaling pathwayGO:200123510.019
single organism membrane fusionGO:004480120.019
positive regulation of cellular amine metabolic processGO:003324000.019
meiotic nuclear divisionGO:000712640.019
regulation of programmed cell deathGO:00430671010.019
embryo development ending in birth or egg hatchingGO:00097922710.019
regulation of erk1 and erk2 cascadeGO:007037240.019
negative regulation of protein serine threonine kinase activityGO:007190120.019
anterior posterior pattern specificationGO:00099521520.019
localization of cellGO:00516742440.019
heterocycle biosynthetic processGO:00181302150.018
tube closureGO:006060610.018
membrane fusionGO:006102520.018
developmental programmed cell deathGO:001062340.018
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.018
negative regulation of cellular catabolic processGO:003133030.018
apoptotic process involved in developmentGO:190274220.018
protein homooligomerizationGO:005126030.018
positive regulation of striated muscle tissue developmentGO:004584410.018
regulation of multicellular organism growthGO:004001440.018
cellular response to starvationGO:000926710.018
neuroblast proliferationGO:000740520.018
epithelial tube morphogenesisGO:00605621480.018
negative regulation of protein localization to nucleusGO:190018120.018
immune system processGO:00023762410.018
intracellular signal transductionGO:0035556850.018
negative regulation of tor signalingGO:003200720.018
negative regulation of translationGO:001714810.018
hematopoietic or lymphoid organ developmentGO:00485341910.018
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.018
cell agingGO:000756920.018
macromolecule catabolic processGO:0009057150.017
protein acylationGO:004354330.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
cell morphogenesis involved in differentiationGO:00009041950.017
regulation of response to extracellular stimulusGO:003210410.017
digestive tract morphogenesisGO:00485462310.017
proteolysisGO:0006508380.017
mitotic cell cycleGO:0000278640.017
maternal determination of anterior posterior axis embryoGO:000835840.017
carboxylic acid metabolic processGO:0019752220.017
regulation of cell deathGO:00109411030.017
negative regulation of cytoplasmic transportGO:190365020.017
dorsal ventral pattern formationGO:00099531250.017
regulation of cellular protein catabolic processGO:190336210.017
gland developmentGO:00487321430.017
hormone secretionGO:004687920.017
catabolic processGO:0009056320.017
regulation of response to nutrient levelsGO:003210710.017
positive regulation of cell adhesionGO:004578510.017
negative regulation of macromolecule biosynthetic processGO:0010558480.016
cellular response to hormone stimulusGO:0032870390.016
negative regulation of cellular metabolic processGO:0031324770.016
regulation of cell activationGO:005086510.016
positive regulation of immune effector processGO:000269930.016
response to uvGO:000941130.016
nucleobase containing compound biosynthetic processGO:00346542050.016
cellular response to oxygen levelsGO:007145310.016
cell motilityGO:00488702440.016
heart developmentGO:00075073130.016
programmed cell deathGO:00125011190.016
positive regulation of cellular catabolic processGO:003133130.016
negative regulation of intracellular protein transportGO:009031730.016
glial cell proliferationGO:001400940.016
striated muscle cell differentiationGO:00511461290.016
primary neural tube formationGO:001402010.016
positive regulation of cellular component biogenesisGO:004408930.015
glucose homeostasisGO:004259310.015
positive regulation of stress activated mapk cascadeGO:003287430.015
transcription from rna polymerase ii promoterGO:0006366800.015
digestive system developmentGO:00551232890.015
regulation of receptor activityGO:001046920.015
cell migration involved in gastrulationGO:0042074790.015
cell cycle g1 s phase transitionGO:004484310.015
secondary metabolic processGO:001974830.015
cell part morphogenesisGO:00329902460.015
golgi vesicle transportGO:004819330.015
regulation of protein import into nucleusGO:004230620.015
regulation of nucleobase containing compound metabolic processGO:00192192500.015
cellular amide metabolic processGO:004360340.015
negative regulation of intracellular transportGO:003238730.015
negative regulation of protein import into nucleusGO:004230820.015
cellular response to endogenous stimulusGO:0071495680.015
regulation of protein targetingGO:190353320.014
negative regulation of gene expressionGO:0010629650.014
positive regulation of cell communicationGO:0010647560.014
regulation of autophagyGO:001050630.014
negative regulation of gliogenesisGO:001401410.014
wnt signaling pathwayGO:0016055800.014
lipid storageGO:001991510.014
response to corticosteroidGO:003196010.014
cellular component disassemblyGO:002241110.014
leukocyte proliferationGO:007066110.014
centrosome organizationGO:005129710.014
rna 3 end processingGO:003112320.014
positive regulation of map kinase activityGO:004340630.014
peptidyl threonine phosphorylationGO:001810710.014
exocytosisGO:000688710.014
intracellular mrna localizationGO:000829810.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
regulation of cellular biosynthetic processGO:00313262450.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
regulation of myotube differentiationGO:001083020.014
neuron neuron synaptic transmissionGO:000727010.014
cellular response to hypoxiaGO:007145610.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.014
regulation of mitotic cell cycle phase transitionGO:190199080.014
regulation of synapse assemblyGO:005196330.014
endosomal transportGO:001619720.014
ameboidal type cell migrationGO:00016671430.014
homeostatic processGO:00425921420.014
aromatic compound biosynthetic processGO:00194382170.014
chemosensory behaviorGO:000763510.014
positive regulation of response to stimulusGO:0048584800.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
regulation of synapse organizationGO:005080730.014
g1 s transition of mitotic cell cycleGO:000008210.014
muscle structure developmentGO:00610611960.014
developmental maturationGO:0021700340.014
macroautophagyGO:001623610.014
nuclear exportGO:005116810.014
negative regulation of sequestering of calcium ionGO:005128340.013
eye developmentGO:00016542770.013
positive regulation of secretionGO:005104710.013
somatic muscle developmentGO:000752540.013
adherens junction organizationGO:003433240.013
xenobiotic metabolic processGO:000680540.013
response to hexoseGO:000974630.013
negative regulation of biosynthetic processGO:0009890550.013
ribonucleoside monophosphate catabolic processGO:000915840.013
regulation of cytokine productionGO:000181730.013
carbohydrate homeostasisGO:003350010.013
protein k48 linked ubiquitinationGO:007093610.013
regulation of response to stressGO:0080134360.013
sprouting angiogenesisGO:0002040530.013
cell cycle processGO:0022402530.013
regulation of cell shapeGO:000836010.013
negative regulation of phosphorus metabolic processGO:0010563130.013
sex determinationGO:000753010.013
cellular localizationGO:0051641970.013
cell matrix adhesionGO:000716040.013
response to monosaccharideGO:003428430.013
cortical cytoskeleton organizationGO:003086510.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
synaptic vesicle transportGO:004848910.013
response to nutrientGO:000758430.013
negative regulation of apoptotic processGO:0043066550.013
internal peptidyl lysine acetylationGO:001839320.013
nucleobase containing compound metabolic processGO:00061392740.013
cellular component maintenanceGO:004395430.013
organic substance catabolic processGO:1901575280.013
regulation of dna templated transcription elongationGO:003278430.013
regulation of jak stat cascadeGO:004642530.013
regulation of localizationGO:00328791040.013
mitotic cell cycle processGO:1903047480.013
response to hormoneGO:0009725480.013
negative regulation of ras protein signal transductionGO:004658010.013
lipid metabolic processGO:0006629520.012
post embryonic organ developmentGO:004856940.012
cellular response to decreased oxygen levelsGO:003629410.012
synaptic growth at neuromuscular junctionGO:005112420.012
cellular component assemblyGO:00226071700.012
positive regulation of cellular processGO:00485222010.012
response to topologically incorrect proteinGO:003596620.012
organic substance transportGO:0071702580.012
atp catabolic processGO:000620040.012
negative regulation of map kinase activityGO:004340720.012
regulation of stem cell differentiationGO:200073640.012
oocyte anterior posterior axis specificationGO:000731440.012
cellular response to molecule of bacterial originGO:007121930.012
regulation of protein complex assemblyGO:004325430.012
pole plasm assemblyGO:000731540.012
regulation of nucleoside metabolic processGO:000911820.012
negative regulation of mitotic cell cycleGO:0045930110.012
lipid biosynthetic processGO:0008610220.012
cytosolic calcium ion transportGO:006040130.012
sequestering of calcium ionGO:005120830.012
regulation of anatomical structure morphogenesisGO:00226031300.012
regulation of dendrite developmentGO:005077330.012
translational initiationGO:000641330.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
regulation of nucleotide catabolic processGO:003081120.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.012
peptidyl lysine acetylationGO:001839420.012
organelle fusionGO:004828430.012
peptidyl threonine modificationGO:001821010.012
regulation of neural precursor cell proliferationGO:200017730.012
cellular modified amino acid metabolic processGO:000657530.012
regulation of rna metabolic processGO:00512522240.012
somatic stem cell maintenanceGO:003501910.012
myeloid cell developmentGO:0061515320.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
lysosomal transportGO:000704120.012
nucleoside monophosphate catabolic processGO:000912540.012
regulation of translational initiationGO:000644610.011
positive regulation of cell activationGO:005086710.011
cytoskeleton dependent cytokinesisGO:006164030.011
mitotic nuclear divisionGO:0007067180.011
regulation of sequestering of calcium ionGO:005128240.011
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.011
gastrulationGO:00073692080.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
chordate embryonic developmentGO:00430092710.011
protein stabilizationGO:005082120.011
protein phosphorylationGO:0006468470.011
response to external stimulusGO:00096052640.011
vacuolar transportGO:000703420.011
regulation of cell substrate adhesionGO:001081010.011
cellular macromolecule localizationGO:0070727210.011
positive regulation of protein complex assemblyGO:003133420.011
negative regulation of reproductive processGO:200024230.011
negative regulation of signal transductionGO:0009968940.011
lymphocyte proliferationGO:004665110.011
nucleic acid transportGO:005065720.011
negative regulation of cell differentiationGO:0045596460.011
axis specificationGO:0009798430.011
regulation of establishment of protein localization to plasma membraneGO:009000310.011
cortical actin cytoskeleton organizationGO:003086610.011
type b pancreatic cell developmentGO:000332340.011
release of sequestered calcium ion into cytosolGO:005120930.011
positive regulation of metabolic processGO:00098931080.011
negative regulation of developmental processGO:0051093650.011
regulation of metal ion transportGO:001095940.011
negative regulation of cell deathGO:0060548600.011
b cell activationGO:004211320.011
calcium ion transport into cytosolGO:006040230.011
regulation of carbohydrate metabolic processGO:000610940.011
mononuclear cell proliferationGO:003294310.011
glycerolipid biosynthetic processGO:004501710.011
gtp catabolic processGO:000618420.011
response to fluid shear stressGO:003440520.010
positive regulation of chromatin modificationGO:190331010.010
protein modification by small protein conjugationGO:0032446130.010
signal transduction in absence of ligandGO:003803410.010
organelle assemblyGO:00709251100.010
rna transportGO:005065820.010
carbohydrate biosynthetic processGO:001605110.010
positive regulation of gtpase activityGO:004354710.010
negative regulation of multi organism processGO:004390130.010
negative regulation of cell communicationGO:0010648960.010
regulation of cell differentiationGO:00455951420.010
positive regulation of canonical wnt signaling pathwayGO:009026340.010
establishment of synaptic vesicle localizationGO:009748010.010
regulation of epithelial to mesenchymal transitionGO:001071730.010
regulation of protein localization to plasma membraneGO:190307610.010
tissue remodelingGO:004877140.010
negative regulation of programmed cell deathGO:0043069580.010
regulation of molecular functionGO:0065009700.010
cellular response to biotic stimulusGO:007121630.010
axonogenesisGO:00074091520.010
activation of mapk activityGO:000018730.010
positive regulation of dna metabolic processGO:005105410.010
development of primary female sexual characteristicsGO:004654540.010
convergent extension involved in gastrulationGO:0060027710.010
regulation of reactive oxygen species metabolic processGO:200037720.010
negative regulation of cell cycle phase transitionGO:190198850.010
regulation of protein bindingGO:004339330.010
regulation of purine nucleotide catabolic processGO:003312120.010
macromolecular complex subunit organizationGO:0043933740.010
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.010
cellular respirationGO:004533330.010
response to abiotic stimulusGO:00096281220.010
protein n linked glycosylationGO:000648710.010
establishment of rna localizationGO:005123630.010

fbxw2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
cancerDOID:16200.015
organ system cancerDOID:005068600.015
disease of cellular proliferationDOID:1456600.015
nervous system diseaseDOID:86300.014
musculoskeletal system diseaseDOID:1700.012
disease of metabolismDOID:001466700.011