Danio rerio

0 known processes

ube3a

ubiquitin protein ligase E3A

(Aliases: zgc:92173,im:7140733,MGC174322,MGC92173)

ube3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.070
agingGO:000756820.058
positive regulation of transportGO:005105020.043
multicellular organism growthGO:003526440.043
modification dependent protein catabolic processGO:001994130.040
phagocytosisGO:000690930.038
proteolysis involved in cellular protein catabolic processGO:005160330.038
cellular protein catabolic processGO:004425740.038
nitrogen compound metabolic processGO:00068073190.036
ubiquitin dependent protein catabolic processGO:000651130.036
cellular macromolecule metabolic processGO:00442603910.036
cellular nitrogen compound metabolic processGO:00346412900.035
establishment of protein localization to organelleGO:007259440.034
modification dependent macromolecule catabolic processGO:004363230.034
maintenance of locationGO:005123540.033
mitochondrion organizationGO:000700540.032
positive regulation of catabolic processGO:000989640.032
gene expressionGO:00104672520.031
cellular response to external stimulusGO:007149620.030
cellular amine metabolic processGO:004410620.030
proteasomal protein catabolic processGO:001049820.029
cellular biosynthetic processGO:00442492860.029
membrane fusionGO:006102520.029
signal transductionGO:00071654550.028
positive regulation of cellular component biogenesisGO:004408930.028
nucleocytoplasmic transportGO:000691340.028
lipid storageGO:001991510.028
regulation of multicellular organism growthGO:004001440.028
guanosine containing compound metabolic processGO:190106840.028
nuclear transportGO:005116940.028
biosynthetic processGO:00090582940.028
rna localizationGO:000640340.027
heterocycle metabolic processGO:00464832900.027
positive regulation of cellular catabolic processGO:003133130.027
nucleobase containing compound metabolic processGO:00061392740.027
organic substance biosynthetic processGO:19015762890.026
autophagyGO:000691440.026
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
gtp catabolic processGO:000618420.026
organic cyclic compound metabolic processGO:19013603010.026
stem cell maintenanceGO:001982740.026
gtp metabolic processGO:004603940.025
protein importGO:001703830.025
regulation of cytokine productionGO:000181730.025
nucleic acid metabolic processGO:00903042440.025
amine metabolic processGO:000930820.025
protein localization to nucleusGO:003450430.024
organelle fusionGO:004828430.024
regulation of protein catabolic processGO:004217610.024
regulation of synapse organizationGO:005080730.024
regulation of cellular metabolic processGO:00313233200.024
regulation of establishment of protein localizationGO:007020140.024
regulation of cellular amine metabolic processGO:003323800.024
regulation of cellular amino acid metabolic processGO:000652100.024
regulation of protein complex assemblyGO:004325430.024
cellular aromatic compound metabolic processGO:00067252950.024
regulation of protein modification by small protein conjugation or removalGO:190332030.024
guanosine containing compound catabolic processGO:190106920.024
positive regulation of cell cycleGO:004578730.024
cellular nitrogen compound biosynthetic processGO:00442712180.023
cellular response to extracellular stimulusGO:003166820.023
endosomal transportGO:001619720.023
cellular ketone metabolic processGO:0042180110.023
regulation of primary metabolic processGO:00800903110.023
protein metabolic processGO:00195381830.023
central nervous system developmentGO:00074173870.023
cell surface receptor signaling pathwayGO:00071663250.023
nuclear importGO:005117030.023
protein localization to plasma membraneGO:007265910.023
regulation of macromolecule metabolic processGO:00602553170.023
single organism nuclear importGO:190259330.023
negative regulation of protein phosphorylationGO:000193340.023
response to drugGO:004249330.022
regulation of protein transportGO:005122330.022
protein acetylationGO:000647320.022
regulation of meiotic cell cycleGO:005144510.022
cellular response to starvationGO:000926710.022
single organism membrane fusionGO:004480120.022
regulation of metabolic processGO:00192223590.022
golgi vesicle transportGO:004819330.022
rna metabolic processGO:00160702190.022
meiotic nuclear divisionGO:000712640.022
cellular response to nutrient levelsGO:003166920.022
heterocycle biosynthetic processGO:00181302150.022
cytokinesisGO:000091030.021
stem cell proliferationGO:007208940.021
regulation of protein ubiquitinationGO:003139630.021
regulation of cytoplasmic transportGO:190364940.021
protein targeting to nucleusGO:004474430.021
negative regulation of biological processGO:00485193040.021
protein acylationGO:004354330.021
establishment of localizationGO:00512342440.021
response to chemicalGO:00422213200.021
protein import into nucleusGO:000660630.020
macromolecule biosynthetic processGO:00090592270.020
peptidyl lysine acetylationGO:001839420.020
tube morphogenesisGO:00352393490.020
single organism metabolic processGO:00447102170.020
cell part morphogenesisGO:00329902460.020
regulation of cell shapeGO:000836010.020
meiotic cell cycle processGO:190304630.020
regulation of cellular ketone metabolic processGO:001056570.020
cellular amino acid metabolic processGO:000652070.020
locomotor rhythmGO:004547530.020
neuron differentiationGO:00301823530.020
regulation of nitrogen compound metabolic processGO:00511712510.020
response to stressGO:00069502630.020
regulation of mrna processingGO:005068430.020
cognitionGO:005089010.020
cell projection organizationGO:00300302840.020
organonitrogen compound metabolic processGO:1901564740.020
negative regulation of cellular processGO:00485232830.019
internal protein amino acid acetylationGO:000647520.019
regulation of gene expressionGO:00104682650.019
regulation of synaptic plasticityGO:004816710.019
regulation of mrna splicing via spliceosomeGO:004802430.019
cellular component disassemblyGO:002241110.019
regulation of cellular biosynthetic processGO:00313262450.019
protein complex disassemblyGO:004324110.019
response to external stimulusGO:00096052640.019
regulation of multicellular organismal developmentGO:20000262230.019
small molecule metabolic processGO:0044281770.019
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.019
regulation of synapse assemblyGO:005196330.019
regulation of bindingGO:005109830.019
spermatid developmentGO:000728620.019
cellular carbohydrate metabolic processGO:004426240.019
cellular component movementGO:00069283350.019
regulation of protein localization to nucleusGO:190018020.019
positive regulation of cellular amine metabolic processGO:003324000.019
cellular component morphogenesisGO:00329893360.019
regulation of signalingGO:00230512350.018
synaptic growth at neuromuscular junctionGO:005112420.018
cellular macromolecule biosynthetic processGO:00346452240.018
oxoacid metabolic processGO:0043436310.018
positive regulation of protein complex assemblyGO:003133420.018
regulation of biosynthetic processGO:00098892500.018
locomotionGO:00400113130.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
regulation of cell activationGO:005086510.018
synaptic vesicle localizationGO:009747910.018
transportGO:00068102200.018
cellular protein metabolic processGO:00442671290.018
nucleic acid templated transcriptionGO:00976591810.018
cell cycle g1 s phase transitionGO:004484310.018
regulation of multicellular organismal processGO:00512392770.018
cellular respirationGO:004533330.018
regulation of protein import into nucleusGO:004230620.018
cell projection morphogenesisGO:00488582440.018
regulation of intracellular protein transportGO:003315730.018
regulation of developmental processGO:00507932470.018
brain developmentGO:00074202930.018
phagocytosis engulfmentGO:000691110.018
cell morphogenesisGO:00009022890.018
establishment of synaptic vesicle localizationGO:009748010.018
negative regulation of protein kinase activityGO:000646940.017
carboxylic acid metabolic processGO:0019752220.017
positive regulation of cytokine productionGO:000181920.017
g1 s transition of mitotic cell cycleGO:000008210.017
positive regulation of secretionGO:005104710.017
organelle organizationGO:00069962270.017
neuroblast proliferationGO:000740520.017
regulation of purine nucleotide catabolic processGO:003312120.017
protein dephosphorylationGO:000647030.017
synaptic vesicle transportGO:004848910.017
regulation of response to stimulusGO:00485832690.017
cellular response to biotic stimulusGO:007121630.017
regulation of signal transductionGO:00099662250.017
negative regulation of kinase activityGO:003367340.017
regulation of nucleotide catabolic processGO:003081120.017
single organism localizationGO:19025782250.017
nucleic acid transportGO:005065720.017
compound eye developmentGO:004874920.017
response to uvGO:000941130.017
cell migrationGO:00164772370.017
transcription dna templatedGO:00063511810.017
regulation of nucleocytoplasmic transportGO:004682220.017
regulation of alternative mrna splicing via spliceosomeGO:000038110.017
macromolecular complex disassemblyGO:003298410.017
positive regulation of cytoskeleton organizationGO:005149530.017
head developmentGO:00603223030.017
growthGO:00400071740.017
extrinsic apoptotic signaling pathwayGO:009719130.017
exocytosisGO:000688710.016
membrane invaginationGO:001032410.016
single organism transportGO:00447652060.016
regulation of rna biosynthetic processGO:20011412130.016
internal peptidyl lysine acetylationGO:001839320.016
cellular response to molecule of bacterial originGO:007121930.016
regulation of macromolecule biosynthetic processGO:00105562250.016
peptidyl serine phosphorylationGO:001810510.016
actin polymerization or depolymerizationGO:000815420.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
translational initiationGO:000641330.016
cellular response to lipopolysaccharideGO:007122230.016
adult behaviorGO:003053420.016
regulation of protein targetingGO:190353320.016
organic acid metabolic processGO:0006082310.016
actin filament polymerizationGO:003004120.016
regionalizationGO:00030022740.016
system processGO:00030081850.016
positive regulation of secretion by cellGO:190353210.016
protein polymerizationGO:005125840.016
cell motilityGO:00488702440.016
positive regulation of stress activated mapk cascadeGO:003287430.016
regulation of organ growthGO:004662030.015
i kappab kinase nf kappab signalingGO:000724940.015
embryonic organ developmentGO:00485683810.015
rna biosynthetic processGO:00327741810.015
regulation of nucleoside metabolic processGO:000911820.015
aromatic compound biosynthetic processGO:00194382170.015
regulation of biological qualityGO:00650082630.015
peptidyl serine modificationGO:001820920.015
regulation of cell communicationGO:00106462320.015
immune system processGO:00023762410.015
organic cyclic compound biosynthetic processGO:19013622230.015
nucleobase containing compound biosynthetic processGO:00346542050.015
protein polyubiquitinationGO:000020940.015
regulation of gtp catabolic processGO:003312420.015
morphogenesis of an epitheliumGO:00020093330.015
regulation of cellular protein catabolic processGO:190336210.015
response to topologically incorrect proteinGO:003596620.015
nuclear exportGO:005116810.015
regulation of nucleobase containing compound metabolic processGO:00192192500.015
spermatid differentiationGO:004851520.015
meiotic chromosome segregationGO:004513230.015
regulation of stem cell proliferationGO:007209120.015
single organism organelle organizationGO:19025891990.015
positive regulation of cell adhesionGO:004578510.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
cytoskeleton dependent cytokinesisGO:006164030.015
regulation of anatomical structure morphogenesisGO:00226031300.015
positive regulation of gtpase activityGO:004354710.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
centrosome organizationGO:005129710.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
sequestering of metal ionGO:005123830.014
regulation of circadian rhythmGO:004275240.014
negative regulation of catabolic processGO:000989530.014
tissue remodelingGO:004877140.014
production of molecular mediator of immune responseGO:000244020.014
cellular component assemblyGO:00226071700.014
regulation of autophagyGO:001050630.014
positive regulation of cellular processGO:00485222010.014
sensory organ developmentGO:00074233930.014
regulation of organelle assemblyGO:190211540.014
establishment of protein localization to plasma membraneGO:009000210.014
regulation of gtpase activityGO:004308720.014
protein secretionGO:000930610.014
generation of neuronsGO:00486993850.014
cellular amide metabolic processGO:004360340.014
cell matrix adhesionGO:000716040.014
regulation of neural precursor cell proliferationGO:200017730.014
embryo development ending in birth or egg hatchingGO:00097922710.014
positive regulation of cell activationGO:005086710.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
neuron developmentGO:00486662620.014
localization of cellGO:00516742440.014
vasculature developmentGO:00019442780.014
positive regulation of gtp catabolic processGO:003312610.014
germ line stem cell maintenanceGO:003071820.014
g2 dna damage checkpointGO:003157230.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
cellular component biogenesisGO:00440851780.014
antimicrobial humoral responseGO:001973020.014
regulation of protein polymerizationGO:003227120.014
ribonucleoside monophosphate catabolic processGO:000915840.014
regulation of rna metabolic processGO:00512522240.013
regulation of reproductive processGO:200024140.013
leukocyte proliferationGO:007066110.013
b cell activationGO:004211320.013
rna transportGO:005065820.013
positive regulation of dna metabolic processGO:005105410.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
positive regulation of nucleotide catabolic processGO:003081310.013
stem cell divisionGO:001714510.013
heart developmentGO:00075073130.013
macromolecule modificationGO:00434121110.013
gastrulationGO:00073692080.013
protein modification processGO:00362111000.013
atp catabolic processGO:000620040.013
regulation of erk1 and erk2 cascadeGO:007037240.013
alcohol biosynthetic processGO:004616520.013
positive regulation of biological processGO:00485182530.013
regulation of carbohydrate metabolic processGO:000610940.013
digestive system developmentGO:00551232890.013
cytoplasm organizationGO:000702840.013
digestive tract developmentGO:00485652650.013
response to carbohydrateGO:000974330.013
nucleobase containing compound transportGO:001593120.013
positive regulation of translationGO:004572710.013
neurotransmitter transportGO:000683620.013
erk1 and erk2 cascadeGO:007037140.013
single fertilizationGO:000733830.013
fertilizationGO:000956630.013
negative regulation of sequestering of calcium ionGO:005128340.013
positive regulation of immune effector processGO:000269930.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
interspecies interaction between organismsGO:004441940.013
blood vessel developmentGO:00015682460.013
macroautophagyGO:001623610.013
sequestering of calcium ionGO:005120830.013
axon developmentGO:00615641660.013
digestive tract morphogenesisGO:00485462310.013
establishment of rna localizationGO:005123630.013
regulation of cell projection assemblyGO:006049140.012
apoptotic processGO:00069151160.012
nucleoside monophosphate catabolic processGO:000912540.012
eye developmentGO:00016542770.012
chemosensory behaviorGO:000763510.012
regulation of reactive oxygen species metabolic processGO:200037720.012
negative regulation of protein transportGO:005122430.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
negative regulation of synapse assemblyGO:005196420.012
synaptic vesicle recyclingGO:003646510.012
positive regulation of map kinase activityGO:004340630.012
positive regulation of nucleoside metabolic processGO:004597910.012
axonogenesisGO:00074091520.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
cellular response to radiationGO:007147840.012
positive regulation of inflammatory responseGO:005072910.012
immune system developmentGO:00025201910.012
startle responseGO:000196440.012
mitotic cell cycle embryonicGO:004544820.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
negative regulation of cellular catabolic processGO:003133030.012
regulation of protein complex disassemblyGO:004324410.012
regulation of inflammatory responseGO:005072720.012
negative regulation of cytokine productionGO:000181810.012
regulation of stem cell differentiationGO:200073640.012
alternative mrna splicing via spliceosomeGO:000038010.012
positive regulation of leukocyte differentiationGO:190210710.012
regulation of transcription dna templatedGO:00063552130.012
negative regulation of intracellular transportGO:003238730.012
development of primary female sexual characteristicsGO:004654540.012
response to monosaccharideGO:003428430.012
regulation of cell developmentGO:00602841000.012
neuron projection developmentGO:00311751800.012
neurotransmitter secretionGO:000726920.012
transcription from rna polymerase ii promoterGO:0006366800.012
negative regulation of cytoplasmic transportGO:190365020.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
negative regulation of mapk cascadeGO:004340940.012
regulation of cellular component organizationGO:0051128860.012
calcium ion transport into cytosolGO:006040230.011
enzyme linked receptor protein signaling pathwayGO:00071671060.011
secondary metabolic processGO:001974830.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
hemopoiesisGO:00300971830.011
mononuclear cell proliferationGO:003294310.011
cilium morphogenesisGO:0060271850.011
specification of symmetryGO:00097992040.011
response to hydrogen peroxideGO:004254230.011
cellular localizationGO:0051641970.011
pole plasm assemblyGO:000731540.011
regulation of cell substrate adhesionGO:001081010.011
carbohydrate biosynthetic processGO:001605110.011
positive regulation of jnk cascadeGO:004633030.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
regulation of production of molecular mediator of immune responseGO:000270010.011
hormone secretionGO:004687920.011
cell substrate adhesionGO:003158940.011
regulation of sequestering of calcium ionGO:005128240.011
vacuolar transportGO:000703420.011
developmental growthGO:00485891660.011
negative regulation of protein complex assemblyGO:003133310.011
regulation of protein bindingGO:004339330.011
response to alkaloidGO:004327920.011
mitochondrial transportGO:000683920.011
regulation of jak stat cascadeGO:004642530.011
cellular protein modification processGO:00064641000.011
intracellular mrna localizationGO:000829810.011
cellular response to topologically incorrect proteinGO:003596720.011
neuron neuron synaptic transmissionGO:000727010.011
lamellipodium organizationGO:009758110.011
negative regulation of macromolecule metabolic processGO:0010605760.011
negative regulation of map kinase activityGO:004340720.011
oocyte anterior posterior axis specificationGO:000731440.011
er to golgi vesicle mediated transportGO:000688810.011
intracellular signal transductionGO:0035556850.011
carbohydrate homeostasisGO:003350010.011
cellular response to chemical stimulusGO:00708871570.011
peptide transportGO:001583310.011
determination of bilateral symmetryGO:00098552040.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
negative regulation of cell communicationGO:0010648960.011
regulation of epithelial cell proliferationGO:005067830.011
dorsal ventral pattern formationGO:00099531250.011
regulation of cell differentiationGO:00455951420.011
lateral inhibitionGO:004633110.011
ameboidal type cell migrationGO:00016671430.011
nephron morphogenesisGO:007202820.011
negative regulation of signal transductionGO:0009968940.011
adherens junction organizationGO:003433240.011
response to organic substanceGO:00100331530.011
post golgi vesicle mediated transportGO:000689210.011
blood vessel morphogenesisGO:00485142160.011
female gonad developmentGO:000858540.011
regulation of metal ion transportGO:001095940.011
mitotic dna damage checkpointGO:004477340.011
somatic muscle developmentGO:000752540.011
activation of mapk activityGO:000018730.011
negative regulation of metabolic processGO:0009892860.010
female sex differentiationGO:004666040.010
chordate embryonic developmentGO:00430092710.010
dna templated transcription elongationGO:000635430.010
somatic stem cell maintenanceGO:003501910.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
response to unfolded proteinGO:000698620.010
protein homooligomerizationGO:005126030.010
positive regulation of chromosome organizationGO:200125210.010
neuromuscular synaptic transmissionGO:000727420.010
negative regulation of multi organism processGO:004390130.010
regulation of transporter activityGO:003240920.010
gland developmentGO:00487321430.010
regulation of rho protein signal transductionGO:003502320.010
response to external biotic stimulusGO:0043207970.010
positive regulation of i kappab kinase nf kappab signalingGO:004312330.010
negative regulation of signalingGO:0023057960.010
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.010
response to glucoseGO:000974930.010
negative regulation of response to stimulusGO:00485851040.010
mrna transportGO:005102820.010
lamellipodium assemblyGO:003003210.010

ube3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
nervous system diseaseDOID:86300.025
disease of cellular proliferationDOID:1456600.017
organ system cancerDOID:005068600.015
cancerDOID:16200.015
disease of metabolismDOID:001466700.014
musculoskeletal system diseaseDOID:1700.014
sensory system diseaseDOID:005015500.012
muscular diseaseDOID:008000000.011
myopathyDOID:42300.010
muscle tissue diseaseDOID:6600.010