Danio rerio

12 known processes

nod2

nucleotide-binding oligomerization domain containing 2

(Aliases: card15)

nod2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense response to other organismGO:0098542330.416
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.360
Mouse
response to bacteriumGO:0009617580.331
regulation of defense response to virus by hostGO:005069110.325
sialylationGO:009750340.241
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.232
Mouse
response to other organismGO:0051707970.175
response to stressGO:00069502630.166
immune effector processGO:0002252230.144
Mouse
response to dsrnaGO:004333170.126
Mouse
positive regulation of jnk cascadeGO:004633030.125
Mouse
larval developmentGO:000216420.119
defense response to bacteriumGO:0042742220.119
positive regulation of innate immune responseGO:004508980.117
Mouse
regulation of autophagyGO:001050630.112
ganglioside metabolic processGO:000157330.107
positive regulation of epithelial cell proliferationGO:005067910.103
Mouse
positive regulation of defense response to virus by hostGO:000223000.102
erk1 and erk2 cascadeGO:007037140.098
Mouse
membrane lipid biosynthetic processGO:004646720.096
response to biotic stimulusGO:0009607970.088
eye photoreceptor cell developmentGO:0042462300.087
nitrogen compound metabolic processGO:00068073190.085
Mouse
sensory perception of chemical stimulusGO:000760630.084
dicarboxylic acid transportGO:000683510.081
interferon beta productionGO:003260810.080
type i interferon productionGO:003260620.080
defense responseGO:0006952470.079
cognitionGO:005089010.071
response to external biotic stimulusGO:0043207970.070
cellular biosynthetic processGO:00442492860.068
Mouse
heterocycle metabolic processGO:00464832900.068
Mouse
biosynthetic processGO:00090582940.068
Mouse
heterocycle biosynthetic processGO:00181302150.064
Mouse
macromolecule glycosylationGO:004341390.064
purine nucleoside monophosphate catabolic processGO:000912840.062
regulation of interferon beta productionGO:003264810.060
tissue remodelingGO:004877140.058
positive regulation of cell cycleGO:004578730.057
cell surface receptor signaling pathwayGO:00071663250.056
Mouse
regulation of cytokine productionGO:000181730.054
Mouse
regulation of cellular amine metabolic processGO:003323800.054
regulation of cellular carbohydrate metabolic processGO:001067540.054
lipid metabolic processGO:0006629520.054
Mouse
regulation of macromolecule biosynthetic processGO:00105562250.053
Mouse
positive regulation of cellular metabolic processGO:0031325940.052
Mouse
single organism metabolic processGO:00447102170.051
Mouse
protein modification processGO:00362111000.049
Mouse
organic cyclic compound metabolic processGO:19013603010.049
Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.048
Mouse
response to external stimulusGO:00096052640.047
agingGO:000756820.045
mitochondrion organizationGO:000700540.044
protein metabolic processGO:00195381830.043
Mouse
glycosylationGO:0070085110.043
amine metabolic processGO:000930820.041
stem cell maintenanceGO:001982740.040
multicellular organism growthGO:003526440.039
cellular macromolecule biosynthetic processGO:00346452240.039
Mouse
regulation of epithelial cell proliferationGO:005067830.038
Mouse
regulation of gene expressionGO:00104682650.038
Mouse
nucleic acid metabolic processGO:00903042440.038
Mouse
cellular amine metabolic processGO:004410620.038
negative regulation of protein kinase activityGO:000646940.038
negative regulation of cytokine productionGO:000181810.038
Mouse
negative regulation of protein phosphorylationGO:000193340.037
regulation of multicellular organism growthGO:004001440.036
organonitrogen compound biosynthetic processGO:1901566470.036
Mouse
hemopoiesisGO:00300971830.036
regulation of cellular ketone metabolic processGO:001056570.035
regulation of phGO:000688530.034
photoreceptor cell developmentGO:0042461400.034
establishment of protein localization to organelleGO:007259440.034
response to woundingGO:00096111160.033
Mouse
response to organic substanceGO:00100331530.033
Mouse
autophagyGO:000691440.033
cellular response to stressGO:0033554620.033
Mouse
response to corticosteroidGO:003196010.032
response to drugGO:004249330.031
leukocyte differentiationGO:0002521250.031
detection of chemical stimulusGO:000959340.031
regulation of erk1 and erk2 cascadeGO:007037240.031
Mouse
regulation of signal transductionGO:00099662250.030
Mouse
response to xenobiotic stimulusGO:0009410450.030
single organism carbohydrate metabolic processGO:0044723120.030
response to alkaloidGO:004327920.029
mononuclear cell proliferationGO:003294310.029
positive regulation of cellular amino acid metabolic processGO:004576400.029
peptidyl serine phosphorylationGO:001810510.029
positive regulation of cytokine productionGO:000181920.029
Mouse
phagocytosisGO:000690930.029
Mouse
establishment of localizationGO:00512342440.029
Mouse
regulation of striated muscle contractionGO:000694220.029
regulation of inflammatory responseGO:005072720.028
Mouse
positive regulation of transportGO:005105020.028
Mouse
regulation of cellular amino acid metabolic processGO:000652100.028
response to molecule of bacterial originGO:0002237140.028
Mouse
cellular response to chemical stimulusGO:00708871570.028
Mouse
macromolecule modificationGO:00434121110.027
Mouse
positive regulation of cellular component biogenesisGO:004408930.027
positive regulation of erk1 and erk2 cascadeGO:007037420.027
Mouse
long chain fatty acid transportGO:001590910.026
estrogen metabolic processGO:000821020.026
regulation of protein polymerizationGO:003227120.026
cellular response to biotic stimulusGO:007121630.026
Mouse
stem cell proliferationGO:007208940.026
carboxylic acid transportGO:004694280.025
cellular aromatic compound metabolic processGO:00067252950.025
Mouse
anterior posterior pattern specificationGO:00099521520.025
regulation of multicellular organismal processGO:00512392770.025
Mouse
germ line stem cell divisionGO:004207810.025
regulation of cell communicationGO:00106462320.024
Mouse
compound eye developmentGO:004874920.024
cellular ketone metabolic processGO:0042180110.024
multi organism processGO:00517041340.024
positive regulation of secretion by cellGO:190353210.024
Mouse
protein targeting to nucleusGO:004474430.024
cellular response to extracellular stimulusGO:003166820.024
regulation of glial cell differentiationGO:004568540.024
liver developmentGO:0001889960.023
erythrocyte homeostasisGO:0034101550.023
oxoacid metabolic processGO:0043436310.023
cellular response to oxygen levelsGO:007145310.023
enzyme linked receptor protein signaling pathwayGO:00071671060.023
maintenance of locationGO:005123540.023
oocyte maturationGO:000155640.023
carboxylic acid metabolic processGO:0019752220.023
internal protein amino acid acetylationGO:000647520.022
negative regulation of growth rateGO:004596710.022
regulation of gtpase activityGO:004308720.022
positive regulation of cell activationGO:005086710.022
hormone metabolic processGO:0042445190.022
regulation of rac protein signal transductionGO:003502010.022
macromolecule biosynthetic processGO:00090592270.022
Mouse
amino acid transportGO:000686520.022
regulation of biological qualityGO:00650082630.022
polarized epithelial cell differentiationGO:003085940.022
organic acid metabolic processGO:0006082310.022
vasculogenesisGO:0001570410.022
positive regulation of cellular amine metabolic processGO:003324000.021
hematopoietic or lymphoid organ developmentGO:00485341910.021
cellular protein modification processGO:00064641000.021
Mouse
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.021
regulation of biosynthetic processGO:00098892500.021
Mouse
regulation of protein modification by small protein conjugation or removalGO:190332030.020
Mouse
cell cycle g2 m phase transitionGO:004483940.020
opioid receptor signaling pathwayGO:003800330.020
symbiosis encompassing mutualism through parasitismGO:004440340.020
Mouse
regulation of i kappab kinase nf kappab signalingGO:004312240.020
Mouse
transmission of nerve impulseGO:0019226190.020
organonitrogen compound metabolic processGO:1901564740.020
Mouse
regulation of dna replicationGO:000627530.020
response to endogenous stimulusGO:0009719830.020
Mouse
cellular amino acid metabolic processGO:000652070.020
positive regulation of biological processGO:00485182530.020
Mouse
vasculature developmentGO:00019442780.020
guanosine containing compound metabolic processGO:190106840.020
nucleobase containing compound biosynthetic processGO:00346542050.020
Mouse
renal tubule morphogenesisGO:006133310.020
heart processGO:0003015710.020
positive regulation of protein kinase b signalingGO:005189710.020
organelle organizationGO:00069962270.020
cellular response to organic substanceGO:00713101050.019
Mouse
phosphate containing compound metabolic processGO:00067961080.019
Mouse
regulation of purine nucleotide catabolic processGO:003312120.019
foregut morphogenesisGO:000744040.019
peptide metabolic processGO:000651810.019
Mouse
response to virusGO:0009615210.019
morphogenesis of an epitheliumGO:00020093330.019
stem cell fate commitmentGO:004886510.019
cytokine metabolic processGO:004210710.019
regulation of extrinsic apoptotic signaling pathwayGO:200123630.019
cellular protein metabolic processGO:00442671290.019
Mouse
rho protein signal transductionGO:000726650.019
eye photoreceptor cell differentiationGO:0001754450.019
positive regulation of apoptotic signaling pathwayGO:200123510.019
positive regulation of dna metabolic processGO:005105410.019
positive regulation of lipid metabolic processGO:004583410.019
Mouse
positive regulation of endothelial cell differentiationGO:004560320.019
sphingolipid biosynthetic processGO:003014820.019
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.019
regulation of protein transportGO:005122330.018
Mouse
septum transversum developmentGO:000334340.018
response to chemicalGO:00422213200.018
Mouse
cell agingGO:000756920.018
myeloid cell differentiationGO:0030099860.018
nerve developmentGO:0021675450.017
single organism nuclear importGO:190259330.017
cellular response to lipopolysaccharideGO:007122230.017
production of molecular mediator of immune responseGO:000244020.017
Mouse
regulation of endopeptidase activityGO:0052548230.017
regulation of skeletal muscle tissue developmentGO:004864140.017
nephron epithelium morphogenesisGO:007208810.017
nucleocytoplasmic transportGO:000691340.017
smad protein complex assemblyGO:000718310.017
regulation of nucleoside metabolic processGO:000911820.017
regulation of protein metabolic processGO:0051246560.017
Mouse
guanosine containing compound catabolic processGO:190106920.017
regulation of skeletal muscle fiber developmentGO:004874220.017
ph reductionGO:004585110.017
spliceosomal complex assemblyGO:000024510.016
regulation of cellular biosynthetic processGO:00313262450.016
Mouse
muscle organ developmentGO:00075171010.016
somatic stem cell maintenanceGO:003501910.016
purine ribonucleoside monophosphate catabolic processGO:000916940.016
myotube cell developmentGO:0014904350.016
regulation of mrna processingGO:005068430.016
cellular response to molecule of bacterial originGO:007121930.016
Mouse
b cell activationGO:004211320.016
transportGO:00068102200.016
Mouse
peptidyl serine modificationGO:001820920.016
cellular response to external stimulusGO:007149620.016
regulation of cell activationGO:005086510.016
regulation of protein complex assemblyGO:004325430.016
neuron developmentGO:00486662620.016
regulation of nitrogen compound metabolic processGO:00511712510.016
Mouse
negative regulation of kinase activityGO:003367340.016
regulation of mapk cascadeGO:0043408140.016
Mouse
positive regulation of stem cell proliferationGO:200064810.016
regulation of nucleotide catabolic processGO:003081120.016
blood vessel developmentGO:00015682460.016
negative regulation of protein serine threonine kinase activityGO:007190120.015
carbohydrate biosynthetic processGO:001605110.015
germ line stem cell maintenanceGO:003071820.015
chordate embryonic developmentGO:00430092710.015
organic substance biosynthetic processGO:19015762890.015
Mouse
regulation of metabolic processGO:00192223590.015
Mouse
morphogenesis of an epithelial foldGO:006057110.015
positive regulation of map kinase activityGO:004340630.015
Mouse
ribonucleoside monophosphate catabolic processGO:000915840.015
negative regulation of type i interferon productionGO:003248010.015
xenobiotic metabolic processGO:000680540.015
negative regulation of biological processGO:00485193040.015
Mouse
nephron tubule morphogenesisGO:007207810.015
muscle fiber developmentGO:0048747520.015
carbohydrate derivative biosynthetic processGO:1901137430.015
protein acylationGO:004354330.015
g2 m transition of mitotic cell cycleGO:000008640.015
g1 s transition of mitotic cell cycleGO:000008210.015
positive regulation of epithelial cell differentiationGO:003085820.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.015
cellular component biogenesisGO:00440851780.014
stem cell divisionGO:001714510.014
proteolysis involved in cellular protein catabolic processGO:005160330.014
response to exogenous dsrnaGO:004333060.014
Mouse
signal transductionGO:00071654550.014
Mouse
mapk cascadeGO:0000165180.014
Mouse
response to uvGO:000941130.014
positive regulation of chromatin modificationGO:190331010.014
regulation of bindingGO:005109830.014
single organism biosynthetic processGO:0044711710.014
i kappab kinase nf kappab signalingGO:000724940.014
Mouse
regulation of cell developmentGO:00602841000.014
response to vitaminGO:003327330.014
tissue regenerationGO:0042246740.014
negative regulation of epithelial cell migrationGO:001063310.014
cellular nitrogen compound metabolic processGO:00346412900.014
Mouse
regulation of signalingGO:00230512350.014
Mouse
regulation of protein ubiquitinationGO:003139630.014
Mouse
regulation of response to biotic stimulusGO:000283120.014
Mouse
locomotionGO:00400113130.014
Mouse
olfactory placode developmentGO:0071698120.014
gene expressionGO:00104672520.014
Mouse
gtp catabolic processGO:000618420.014
gtp metabolic processGO:004603940.014
lymphocyte proliferationGO:004665110.014
single organism organelle organizationGO:19025891990.014
positive regulation of neuron deathGO:190121610.013
regulation of calcium ion transportGO:005192420.013
regulation of endothelial cell differentiationGO:004560130.013
positive regulation of stress activated mapk cascadeGO:003287430.013
Mouse
nucleic acid transportGO:005065720.013
epithelial tube morphogenesisGO:00605621480.013
b cell mediated immunityGO:001972430.013
Mouse
embryo development ending in birth or egg hatchingGO:00097922710.013
striated muscle tissue developmentGO:00147061100.013
myeloid cell developmentGO:0061515320.013
negative regulation of immune responseGO:005077720.013
Mouse
positive regulation of translationGO:004572710.013
regulation of developmental processGO:00507932470.013
heart morphogenesisGO:00030071560.013
cellular response to hypoxiaGO:007145610.013
nuclear transportGO:005116940.013
synaptic transmission cholinergicGO:000727140.013
male meiosisGO:000714020.013
atp catabolic processGO:000620040.013
response to ketoneGO:190165410.013
pronephros developmentGO:0048793690.013
protein secretionGO:000930610.013
Mouse
regulation of response to stimulusGO:00485832690.013
Mouse
positive regulation of chromosome organizationGO:200125210.013
skeletal system developmentGO:00015011810.013
mechanoreceptor differentiationGO:0042490370.013
eye developmentGO:00016542770.013
endocardium morphogenesisGO:000316040.013
angiogenesisGO:00015251580.013
regulation of mitochondrion organizationGO:001082110.012
negative regulation of multicellular organismal processGO:0051241690.012
Mouse
regulation of rho protein signal transductionGO:003502320.012
positive regulation of cellular processGO:00485222010.012
Mouse
extrinsic apoptotic signaling pathwayGO:009719130.012
muscle tissue developmentGO:00605371100.012
regulation of oligodendrocyte differentiationGO:004871310.012
phosphatidylinositol mediated signalingGO:004801520.012
cellular macromolecule metabolic processGO:00442603910.012
Mouse
immune system developmentGO:00025201910.012
protein importGO:001703830.012
neuroblast fate commitmentGO:001401710.012
positive regulation of lymphocyte mediated immunityGO:000270810.012
Mouse
phosphorylationGO:0016310690.012
Mouse
response to abiotic stimulusGO:00096281220.012
negative regulation of cellular processGO:00485232830.012
Mouse
regulation of metal ion transportGO:001095940.012
response to glucocorticoidGO:005138410.012
small molecule metabolic processGO:0044281770.012
membrane invaginationGO:001032410.012
ceramide biosynthetic processGO:004651310.012
glial cell fate determinationGO:000740310.012
neuroblast differentiationGO:001401610.012
astrocyte differentiationGO:004870810.012
reactive oxygen species biosynthetic processGO:190340910.012
negative regulation of molecular functionGO:0044092230.012
Mouse
response to nutrientGO:000758430.012
membrane lipid metabolic processGO:0006643100.012
nephron morphogenesisGO:007202820.011
actin filament polymerizationGO:003004120.011
somatic cell dna recombinationGO:001644410.011
negative regulation of response to stimulusGO:00485851040.011
Mouse
regulation of gtp catabolic processGO:003312420.011
glycolipid biosynthetic processGO:000924710.011
appendage morphogenesisGO:0035107560.011
regulation of establishment of protein localizationGO:007020140.011
Mouse
regulation of protein localization to nucleusGO:190018020.011
blood vessel morphogenesisGO:00485142160.011
cytoskeleton dependent cytokinesisGO:006164030.011
cellular response to growth factor stimulusGO:0071363390.011
osteoclast differentiationGO:003031610.011
negative regulation of signalingGO:0023057960.011
Mouse
protein import into nucleusGO:000660630.011
cellular response to nutrient levelsGO:003166920.011
protein phosphorylationGO:0006468470.011
Mouse
keratinocyte differentiationGO:003021600.011
internal peptidyl lysine acetylationGO:001839320.011
negative regulation of macromolecule metabolic processGO:0010605760.011
protein localization to nucleusGO:003450430.011
sex determinationGO:000753010.011
exocytosisGO:000688710.011
regulation of leukocyte differentiationGO:190210550.011
transcription dna templatedGO:00063511810.011
Mouse
regulation of intracellular protein transportGO:003315730.011
positive regulation of cytoskeleton organizationGO:005149530.011
exocrine pancreas developmentGO:0031017280.011
apoptotic process involved in developmentGO:190274220.011
embryonic limb morphogenesisGO:003032620.011
defense response to gram positive bacteriumGO:005083060.011
Mouse
regulation of jun kinase activityGO:004350630.011
positive regulation of multicellular organismal processGO:0051240520.011
Mouse
regulation of cytokine biosynthetic processGO:004203510.011
cellular component movementGO:00069283350.011
Mouse
water soluble vitamin metabolic processGO:000676710.011
positive regulation of carbohydrate metabolic processGO:004591310.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.010
fatty acid transportGO:001590810.010
regulation of multicellular organismal developmentGO:20000262230.010
regulation of stem cell proliferationGO:007209120.010
regulation of cardiac muscle contractionGO:005511720.010
hormone biosynthetic processGO:004244630.010
regulation of photoreceptor cell differentiationGO:004653220.010
organ regenerationGO:003110010.010
intracellular signal transductionGO:0035556850.010
Mouse
cellular response to starvationGO:000926710.010
regulation of cytoplasmic transportGO:190364940.010
glial cell proliferationGO:001400940.010
immune system processGO:00023762410.010
Mouse
modulation by virus of host morphology or physiologyGO:001904810.010
epithelial cell morphogenesisGO:000338220.010
nucleoside monophosphate catabolic processGO:000912540.010
actin filament based processGO:0030029640.010
homeostasis of number of cellsGO:0048872620.010
regulation of mesenchymal cell proliferationGO:001046410.010

nod2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.024
disease of anatomical entityDOID:700.020
inherited metabolic disorderDOID:65500.018
musculoskeletal system diseaseDOID:1700.016
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
lysosomal storage diseaseDOID:321100.014
muscle tissue diseaseDOID:6600.011
heart diseaseDOID:11400.011
muscular diseaseDOID:008000000.011
cardiovascular system diseaseDOID:128700.011
cardiomyopathyDOID:005070000.011
myopathyDOID:42300.011