Danio rerio

0 known processes

tpsn

tapasin

(Aliases: SI:dZ179B20.1,SI:dZ179B20.3,SI:dZ179B20.7,zgc:109814,mhc1ufa,mhc1uda)

tpsn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune system processGO:00023762410.143
gene expressionGO:00104672520.090
larval developmentGO:000216420.073
cellular macromolecule metabolic processGO:00442603910.073
lipid storageGO:001991510.062
cellular nitrogen compound metabolic processGO:00346412900.061
regulation of response to stimulusGO:00485832690.060
regulation of biological qualityGO:00650082630.060
nitrogen compound metabolic processGO:00068073190.059
nucleic acid metabolic processGO:00903042440.058
positive regulation of biological processGO:00485182530.057
multicellular organism growthGO:003526440.056
regulation of signal transductionGO:00099662250.055
response to chemicalGO:00422213200.054
stem cell proliferationGO:007208940.054
response to external biotic stimulusGO:0043207970.052
regulation of multicellular organismal processGO:00512392770.052
response to external stimulusGO:00096052640.052
negative regulation of biological processGO:00485193040.051
establishment of localizationGO:00512342440.049
cellular protein metabolic processGO:00442671290.048
maintenance of locationGO:005123540.048
phagocytosisGO:000690930.047
cellular aromatic compound metabolic processGO:00067252950.045
regulation of metal ion transportGO:001095940.045
hematopoietic or lymphoid organ developmentGO:00485341910.044
regulation of macromolecule metabolic processGO:00602553170.044
biosynthetic processGO:00090582940.044
regulation of cell communicationGO:00106462320.043
regulation of cytokine productionGO:000181730.042
transportGO:00068102200.042
oxoacid metabolic processGO:0043436310.042
response to biotic stimulusGO:0009607970.042
regulation of developmental processGO:00507932470.042
cellular ketone metabolic processGO:0042180110.042
regulation of biosynthetic processGO:00098892500.041
i kappab kinase nf kappab signalingGO:000724940.041
pole plasm assemblyGO:000731540.040
signal transductionGO:00071654550.040
negative regulation of cellular processGO:00485232830.040
regulation of metabolic processGO:00192223590.040
carboxylic acid metabolic processGO:0019752220.040
regulation of nitrogen compound metabolic processGO:00511712510.039
organic cyclic compound metabolic processGO:19013603010.038
regulation of peptidyl tyrosine phosphorylationGO:005073010.038
proteolysis involved in cellular protein catabolic processGO:005160330.038
cell surface receptor signaling pathwayGO:00071663250.038
regulation of cellular amino acid metabolic processGO:000652100.038
cellular component movementGO:00069283350.038
organic acid metabolic processGO:0006082310.038
positive regulation of transportGO:005105020.038
small molecule metabolic processGO:0044281770.037
negative regulation of protein phosphorylationGO:000193340.037
regulation of cellular macromolecule biosynthetic processGO:20001122220.037
positive regulation of cellular component biogenesisGO:004408930.037
cellular biosynthetic processGO:00442492860.036
regulation of cellular amine metabolic processGO:003323800.036
cytoplasm organizationGO:000702840.036
rna localizationGO:000640340.036
nucleocytoplasmic transportGO:000691340.036
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.036
positive regulation of cytokine productionGO:000181920.035
regulation of stem cell proliferationGO:007209120.035
regulation of macromolecule biosynthetic processGO:00105562250.035
amine metabolic processGO:000930820.035
cellular amine metabolic processGO:004410620.035
ubiquitin dependent protein catabolic processGO:000651130.035
regulation of nucleobase containing compound metabolic processGO:00192192500.035
regulation of cellular ketone metabolic processGO:001056570.034
modification dependent protein catabolic processGO:001994130.034
oocyte anterior posterior axis specificationGO:000731440.034
protein metabolic processGO:00195381830.033
agingGO:000756820.033
single organism membrane fusionGO:004480120.033
response to stressGO:00069502630.033
nucleobase containing compound metabolic processGO:00061392740.032
regulation of multicellular organism growthGO:004001440.032
regulation of cytoplasmic transportGO:190364940.031
modification dependent macromolecule catabolic processGO:004363230.031
proteasomal protein catabolic processGO:001049820.031
establishment of protein localization to organelleGO:007259440.031
regulation of i kappab kinase nf kappab signalingGO:004312240.031
response to organic substanceGO:00100331530.031
regulation of cellular metabolic processGO:00313233200.031
rna biosynthetic processGO:00327741810.031
cellular modified amino acid metabolic processGO:000657530.031
hemopoiesisGO:00300971830.030
heterocycle metabolic processGO:00464832900.030
cellular component morphogenesisGO:00329893360.030
membrane fusionGO:006102520.030
single organism transportGO:00447652060.030
cellular component assemblyGO:00226071700.030
regulation of protein complex assemblyGO:004325430.029
generation of neuronsGO:00486993850.029
embryo development ending in birth or egg hatchingGO:00097922710.029
regulation of establishment of protein localizationGO:007020140.029
single organism localizationGO:19025782250.029
regulation of signalingGO:00230512350.029
regulation of reproductive processGO:200024140.029
response to drugGO:004249330.029
cellular response to external stimulusGO:007149620.029
regulation of synapse assemblyGO:005196330.028
autophagyGO:000691440.028
positive regulation of map kinase activityGO:004340630.028
cell morphogenesisGO:00009022890.028
neurotransmitter transportGO:000683620.028
regulation of gene expressionGO:00104682650.027
regulation of rna metabolic processGO:00512522240.027
purine ribonucleoside monophosphate catabolic processGO:000916940.027
nucleoside monophosphate catabolic processGO:000912540.027
protein importGO:001703830.027
single organism organelle organizationGO:19025891990.027
positive regulation of cell killingGO:003134320.027
embryonic organ developmentGO:00485683810.026
rna metabolic processGO:00160702190.026
response to other organismGO:0051707970.026
cellular amino acid metabolic processGO:000652070.026
regulation of protein transportGO:005122330.026
regulation of multicellular organismal developmentGO:20000262230.026
single organism nuclear importGO:190259330.026
nuclear transportGO:005116940.026
anterior posterior pattern specificationGO:00099521520.026
cellular protein catabolic processGO:004425740.026
regulation of intracellular protein transportGO:003315730.025
tissue remodelingGO:004877140.025
protein acetylationGO:000647320.025
regulation of reactive oxygen species metabolic processGO:200037720.025
organonitrogen compound metabolic processGO:1901564740.025
cellular protein modification processGO:00064641000.025
maternal determination of anterior posterior axis embryoGO:000835840.025
protein modification processGO:00362111000.025
stem cell maintenanceGO:001982740.025
ribonucleoside monophosphate catabolic processGO:000915840.025
organic cyclic compound biosynthetic processGO:19013622230.024
synaptic growth at neuromuscular junctionGO:005112420.024
nucleobase containing compound biosynthetic processGO:00346542050.024
multi organism processGO:00517041340.024
protein import into nucleusGO:000660630.024
organic substance biosynthetic processGO:19015762890.024
regulation of cellular biosynthetic processGO:00313262450.024
regulation of primary metabolic processGO:00800903110.024
endosomal transportGO:001619720.024
positive regulation of immune effector processGO:000269930.024
meiotic nuclear divisionGO:000712640.023
nuclear importGO:005117030.023
neurotransmitter secretionGO:000726920.023
cell killingGO:000190620.023
intracellular signal transductionGO:0035556850.023
positive regulation of cellular amino acid metabolic processGO:004576400.023
positive regulation of protein complex assemblyGO:003133420.023
leukocyte proliferationGO:007066110.023
internal peptidyl lysine acetylationGO:001839320.022
positive regulation of cellular amine metabolic processGO:003324000.022
peptidyl serine phosphorylationGO:001810510.022
cellular response to chemical stimulusGO:00708871570.022
cellular response to nutrient levelsGO:003166920.022
mitochondrion organizationGO:000700540.022
aromatic compound biosynthetic processGO:00194382170.022
cell projection organizationGO:00300302840.022
neuron differentiationGO:00301823530.022
tube morphogenesisGO:00352393490.022
regulation of stem cell differentiationGO:200073640.022
regulation of filopodium assemblyGO:005148920.022
nucleic acid templated transcriptionGO:00976591810.022
regulation of protein targetingGO:190353320.022
developmental programmed cell deathGO:001062340.021
symbiosis encompassing mutualism through parasitismGO:004440340.021
regulation of cell activationGO:005086510.021
regulation of blood pressureGO:000821710.021
cellular component biogenesisGO:00440851780.021
regulation of tube sizeGO:003515020.021
growthGO:00400071740.021
positive regulation of cell cycleGO:004578730.021
single organism metabolic processGO:00447102170.021
cellular macromolecule biosynthetic processGO:00346452240.021
response to cadmium ionGO:0046686140.021
phosphorus metabolic processGO:00067931090.021
macromolecule modificationGO:00434121110.021
positive regulation of i kappab kinase nf kappab signalingGO:004312330.021
immune system developmentGO:00025201910.021
organelle fusionGO:004828430.021
regulation of calcium ion transportGO:005192420.021
cell cycle g1 s phase transitionGO:004484310.020
atp catabolic processGO:000620040.020
peptidyl serine modificationGO:001820920.020
cell projection morphogenesisGO:00488582440.020
cellular nitrogen compound biosynthetic processGO:00442712180.020
positive regulation of catabolic processGO:000989640.020
vasculature developmentGO:00019442780.020
peptidyl lysine acetylationGO:001839420.020
positive regulation of muscle cell differentiationGO:005114910.020
cellular response to starvationGO:000926710.020
vacuolar transportGO:000703420.020
negative regulation of response to stimulusGO:00485851040.020
negative regulation of nucleocytoplasmic transportGO:004682320.020
positive regulation of stress activated mapk cascadeGO:003287430.020
regulation of cell shapeGO:000836010.020
digestive system developmentGO:00551232890.020
regulation of transcription dna templatedGO:00063552130.020
macromolecule biosynthetic processGO:00090592270.019
regulation of synaptic plasticityGO:004816710.019
regulation of synapse organizationGO:005080730.019
regulation of rna biosynthetic processGO:20011412130.019
locomotionGO:00400113130.019
regulation of protein import into nucleusGO:004230620.019
transcription dna templatedGO:00063511810.019
cellular response to extracellular stimulusGO:003166820.019
regulation of protein localization to nucleusGO:190018020.019
regulation of protein catabolic processGO:004217610.019
hormone secretionGO:004687920.019
gtp catabolic processGO:000618420.019
regulation of extrinsic apoptotic signaling pathwayGO:200123630.019
regulation of synaptic growth at neuromuscular junctionGO:000858210.019
synaptic vesicle transportGO:004848910.019
guanosine containing compound metabolic processGO:190106840.018
protein targeting to nucleusGO:004474430.018
interspecies interaction between organismsGO:004441940.018
purine nucleoside monophosphate catabolic processGO:000912840.018
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.018
negative regulation of intracellular transportGO:003238730.018
intracellular mrna localizationGO:000829810.018
cell substrate adhesionGO:003158940.018
peptide metabolic processGO:000651810.018
protein localization to nucleusGO:003450430.018
leukocyte mediated cytotoxicityGO:000190910.018
gtp metabolic processGO:004603940.018
neuroblast proliferationGO:000740520.018
neuron projection morphogenesisGO:00488121610.018
regulation of nucleocytoplasmic transportGO:004682220.018
ion homeostasisGO:0050801410.018
regulation of mrna processingGO:005068430.018
iron ion homeostasisGO:005507240.018
response to uvGO:000941130.017
regulation of ion transmembrane transporter activityGO:003241220.017
regulation of systemic arterial blood pressureGO:000307310.017
centrosome organizationGO:005129710.017
response to nutrientGO:000758430.017
exocytosisGO:000688710.017
guanosine containing compound catabolic processGO:190106920.017
antimicrobial humoral responseGO:001973020.017
organelle organizationGO:00069962270.017
protein acylationGO:004354330.017
phosphate containing compound metabolic processGO:00067961080.017
positive regulation of canonical wnt signaling pathwayGO:009026340.017
muscle cell differentiationGO:00426921390.017
cellular response to molecule of bacterial originGO:007121930.017
cellular response to stressGO:0033554620.017
hormone transportGO:000991420.017
regulation of cell projection assemblyGO:006049140.017
positive regulation of cell activationGO:005086710.017
cellular response to oxygen levelsGO:007145310.017
regulation of jak stat cascadeGO:004642530.017
regulation of response to cytokine stimulusGO:006075930.017
glial cell migrationGO:000834730.017
cognitionGO:005089010.017
cellular amide metabolic processGO:004360340.017
phosphorylationGO:0016310690.017
alpha amino acid metabolic processGO:190160530.017
cell cycle g2 m phase transitionGO:004483940.017
regulation of wound healingGO:006104120.016
positive regulation of cytoskeleton organizationGO:005149530.016
negative regulation of cytoplasmic transportGO:190365020.016
positive regulation of response to stimulusGO:0048584800.016
establishment of synaptic vesicle localizationGO:009748010.016
positive regulation of leukocyte mediated cytotoxicityGO:000191210.016
regulation of neuronal synaptic plasticityGO:004816810.016
negative regulation of kinase activityGO:003367340.016
cell migrationGO:00164772370.016
regulation of oocyte developmentGO:006028130.016
regulation of bindingGO:005109830.016
alcohol biosynthetic processGO:004616520.016
negative regulation of catabolic processGO:000989530.016
positive regulation of secretionGO:005104710.016
regulation of transmembrane transporter activityGO:002289820.016
tyrosine phosphorylation of stat proteinGO:000726010.016
peptide transportGO:001583310.016
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.016
mononuclear cell proliferationGO:003294310.016
regionalizationGO:00030022740.016
regulation of receptor mediated endocytosisGO:004825940.016
spermatid developmentGO:000728620.016
negative regulation of protein kinase activityGO:000646940.016
regulation of nucleotide catabolic processGO:003081120.016
b cell activationGO:004211320.016
positive regulation of cellular processGO:00485222010.016
regulation of inflammatory responseGO:005072720.016
system processGO:00030081850.016
positive regulation of leukocyte mediated immunityGO:000270510.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
internal protein amino acid acetylationGO:000647520.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.015
g1 s transition of mitotic cell cycleGO:000008210.015
blood vessel morphogenesisGO:00485142160.015
meiotic chromosome segregationGO:004513230.015
negative regulation of protein localization to nucleusGO:190018120.015
negative regulation of metabolic processGO:0009892860.015
developmental growthGO:00485891660.015
regulation of cell killingGO:003134120.015
compound eye developmentGO:004874920.015
calcium mediated signalingGO:001972220.015
localization of cellGO:00516742440.015
extrinsic apoptotic signaling pathwayGO:009719130.015
response to vitaminGO:003327330.015
microtubule organizing center organizationGO:003102310.015
production of molecular mediator of immune responseGO:000244020.015
actin filament based movementGO:003004810.015
response to carbohydrateGO:000974330.015
regulation of hematopoietic progenitor cell differentiationGO:190153210.015
female meiotic divisionGO:000714320.015
regulation of sequestering of calcium ionGO:005128240.015
cellular response to decreased oxygen levelsGO:003629410.015
regulation of response to nutrient levelsGO:003210710.015
peptidyl threonine phosphorylationGO:001810710.015
cell motilityGO:00488702440.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
response to corticosteroidGO:003196010.015
cellular component disassemblyGO:002241110.015
segmentationGO:0035282970.015
cellular response to hypoxiaGO:007145610.015
lymphocyte proliferationGO:004665110.015
apoptotic process involved in developmentGO:190274220.015
regulation of tyrosine phosphorylation of stat proteinGO:004250910.015
nuclear exportGO:005116810.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
muscle structure developmentGO:00610611960.015
cellular response to lipopolysaccharideGO:007122230.015
cellular response to organic substanceGO:00713101050.015
heterocycle biosynthetic processGO:00181302150.014
sequestering of metal ionGO:005123830.014
regulation of myotube differentiationGO:001083020.014
oocyte maturationGO:000155640.014
reactive oxygen species metabolic processGO:007259360.014
inositol lipid mediated signalingGO:004801720.014
regulation of cell deathGO:00109411030.014
heart developmentGO:00075073130.014
regulation of response to extracellular stimulusGO:003210410.014
spermatid differentiationGO:004851520.014
response to inorganic substanceGO:0010035380.014
glucose homeostasisGO:004259310.014
regulation of localizationGO:00328791040.014
regulation of neural precursor cell proliferationGO:200017730.014
homeostatic processGO:00425921420.014
calcium ion transport into cytosolGO:006040230.014
negative regulation of cellular catabolic processGO:003133030.014
phagocytosis engulfmentGO:000691110.014
positive regulation of secretion by cellGO:190353210.014
protein dephosphorylationGO:000647030.014
phagosome maturationGO:009038210.014
female sex differentiationGO:004666040.014
cytokinesisGO:000091030.014
cell part morphogenesisGO:00329902460.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.014
zymogen activationGO:003163830.014
positive regulation of translationGO:004572710.014
establishment of protein localization to vacuoleGO:007266610.014
embryonic skeletal system morphogenesisGO:0048704930.014
carbohydrate homeostasisGO:003350010.014
nucleobase containing compound transportGO:001593120.014
single fertilizationGO:000733830.014
sequestering of calcium ionGO:005120830.014
positive regulation of protein polymerizationGO:003227320.014
synaptic vesicle localizationGO:009747910.014
response to alkaloidGO:004327920.014
cellular response to hormone stimulusGO:0032870390.014
organelle assemblyGO:00709251100.014
regulation of blood vessel sizeGO:005088020.013
actin polymerization or depolymerizationGO:000815420.013
b cell differentiationGO:003018310.013
negative regulation of dna metabolic processGO:005105340.013
spindle assemblyGO:005122520.013
regulation of receptor activityGO:001046920.013
negative regulation of chromosome organizationGO:200125110.013
blood vessel developmentGO:00015682460.013
cell matrix adhesionGO:000716040.013
neuron projection developmentGO:00311751800.013
meiotic cell cycle processGO:190304630.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
regulation of neurotransmitter transportGO:005158810.013
membrane invaginationGO:001032410.013
positive regulation of leukocyte differentiationGO:190210710.013
ion transportGO:00068111140.013
g2 m transition of mitotic cell cycleGO:000008640.013
axon developmentGO:00615641660.013
embryonic organ morphogenesisGO:00485622740.013
regulation of meiotic cell cycleGO:005144510.013
lipid catabolic processGO:001604240.013
development of primary female sexual characteristicsGO:004654540.013
cellular response to biotic stimulusGO:007121630.013
morphogenesis of an epitheliumGO:00020093330.013
negative regulation of intracellular protein transportGO:009031730.013
cell deathGO:00082191210.013
regulation of purine nucleotide catabolic processGO:003312120.013
positive regulation of synapse assemblyGO:005196510.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.013
regulation of neurotransmitter secretionGO:004692810.013
establishment of rna localizationGO:005123630.013
response to hexoseGO:000974630.013
sensory perception of chemical stimulusGO:000760630.013
negative regulation of signalingGO:0023057960.013
gland developmentGO:00487321430.013
lateral inhibitionGO:004633110.013
regulation of epithelial cell proliferationGO:005067830.013
protein localization to plasma membraneGO:007265910.013
establishment of protein localization to plasma membraneGO:009000210.013
erk1 and erk2 cascadeGO:007037140.013
negative regulation of multicellular organismal processGO:0051241690.013
positive regulation of reproductive processGO:200024320.013
positive regulation of lymphocyte mediated immunityGO:000270810.013
centrosome cycleGO:000709810.013
somatic muscle developmentGO:000752540.013
germ line stem cell maintenanceGO:003071820.013
negative regulation of protein complex assemblyGO:003133310.013
nucleic acid transportGO:005065720.013
defense response to other organismGO:0098542330.013
cortical cytoskeleton organizationGO:003086510.013
positive regulation of dna metabolic processGO:005105410.013
positive regulation of cell communicationGO:0010647560.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
negative regulation of synapse assemblyGO:005196420.013
cell proliferationGO:0008283800.013
regulation of intracellular signal transductionGO:1902531570.013
positive regulation of cellular catabolic processGO:003133130.013
locomotor rhythmGO:004547530.013
secondary metabolic processGO:001974830.013
centrosome duplicationGO:005129810.013
response to metal ionGO:0010038340.012
regulation of transporter activityGO:003240920.012
cytoskeleton dependent cytokinesisGO:006164030.012
negative regulation of sequestering of calcium ionGO:005128340.012
response to monosaccharideGO:003428430.012
cellular transition metal ion homeostasisGO:004691630.012
immune responseGO:0006955280.012
regulation of alternative mrna splicing via spliceosomeGO:000038110.012
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.012
regulation of biomineral tissue developmentGO:007016720.012
brain developmentGO:00074202930.012
embryonic skeletal system developmentGO:0048706970.012
protein secretionGO:000930610.012
chordate embryonic developmentGO:00430092710.012
adult behaviorGO:003053420.012
protein targeting to vacuoleGO:000662310.012
transcription from rna polymerase ii promoterGO:0006366800.012
negative regulation of macromolecule metabolic processGO:0010605760.012
regulation of immune responseGO:0050776140.012
positive regulation of jnk cascadeGO:004633030.012
deathGO:00162651210.012
positive regulation of biosynthetic processGO:0009891680.012
protein polymerizationGO:005125840.012
regulation of cell differentiationGO:00455951420.012
positive regulation of metabolic processGO:00098931080.012
synaptic vesicle endocytosisGO:004848810.012
rna transportGO:005065820.012
sleepGO:003043110.012
regulation of erk1 and erk2 cascadeGO:007037240.012
regulation of autophagyGO:001050630.012
dna templated transcription elongationGO:000635430.012
carbohydrate biosynthetic processGO:001605110.012
negative regulation of cytokine productionGO:000181810.012
anatomical structure homeostasisGO:0060249360.012
cell cycle arrestGO:000705010.012
protein heterooligomerizationGO:005129110.012
positive regulation of cell adhesionGO:004578510.012
positive regulation of striated muscle cell differentiationGO:005115510.012
regulation of nucleoside metabolic processGO:000911820.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
cellular component assembly involved in morphogenesisGO:00109271070.012
nephron morphogenesisGO:007202820.012
negative regulation of autophagyGO:001050710.012
positive regulation of cell divisionGO:005178120.012
monoamine transportGO:001584410.012
synaptic transmission cholinergicGO:000727140.012
chemosensory behaviorGO:000763510.012
positive regulation of chromatin modificationGO:190331010.011
alternative mrna splicing via spliceosomeGO:000038010.011
regulation of protein bindingGO:004339330.011
peptidyl threonine modificationGO:001821010.011
positive regulation of gene expressionGO:0010628710.011
negative regulation of myeloid cell differentiationGO:004563810.011
synaptic vesicle recyclingGO:003646510.011
positive regulation of nucleoside metabolic processGO:004597910.011
regulation of neurogenesisGO:0050767870.011
bone remodelingGO:004684920.011
gastrulationGO:00073692080.011
protein stabilizationGO:005082120.011
smooth muscle contractionGO:000693920.011

tpsn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
musculoskeletal system diseaseDOID:1700.016
immune system diseaseDOID:291400.016
disease of metabolismDOID:001466700.015
hematopoietic system diseaseDOID:7400.014
muscular diseaseDOID:008000000.014
inherited metabolic disorderDOID:65500.014
muscle tissue diseaseDOID:6600.012
myopathyDOID:42300.012
nervous system diseaseDOID:86300.011
disease of cellular proliferationDOID:1456600.011