Danio rerio

0 known processes

pkm2b

pyruvate kinase, muscle, b

(Aliases: zgc:92037)

pkm2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.128
regulation of cellular metabolic processGO:00313233200.061
agingGO:000756820.059
cellular nitrogen compound biosynthetic processGO:00442712180.057
Rat
regulation of metabolic processGO:00192223590.057
heterocycle biosynthetic processGO:00181302150.056
Rat
maintenance of locationGO:005123540.055
cellular macromolecule metabolic processGO:00442603910.055
regulation of biological qualityGO:00650082630.055
regulation of response to stimulusGO:00485832690.052
regulation of multicellular organismal processGO:00512392770.051
response to chemicalGO:00422213200.049
Rat
cellular nitrogen compound metabolic processGO:00346412900.045
Rat
nucleobase containing compound metabolic processGO:00061392740.045
Rat
organic cyclic compound metabolic processGO:19013603010.044
Rat
signal transductionGO:00071654550.043
multicellular organism growthGO:003526440.043
generation of neuronsGO:00486993850.042
regulation of gene expressionGO:00104682650.041
neuron neuron synaptic transmissionGO:000727010.040
embryonic organ developmentGO:00485683810.040
response to drugGO:004249330.039
positive regulation of transportGO:005105020.038
regulation of developmental processGO:00507932470.038
cell surface receptor signaling pathwayGO:00071663250.037
nitrogen compound metabolic processGO:00068073190.037
Rat
gene expressionGO:00104672520.037
regulation of macromolecule metabolic processGO:00602553170.037
cell part morphogenesisGO:00329902460.037
positive regulation of cell cycleGO:004578730.036
biosynthetic processGO:00090582940.036
Rat
organic cyclic compound biosynthetic processGO:19013622230.036
Rat
locomotionGO:00400113130.035
single organism localizationGO:19025782250.035
phagocytosisGO:000690930.035
regulation of protein transportGO:005122330.035
heterocycle metabolic processGO:00464832900.035
Rat
regulation of multicellular organismal developmentGO:20000262230.034
homeostatic processGO:00425921420.034
cellular biosynthetic processGO:00442492860.034
Rat
regulation of multicellular organism growthGO:004001440.033
organic substance biosynthetic processGO:19015762890.033
Rat
immune system processGO:00023762410.033
cognitionGO:005089010.032
negative regulation of biological processGO:00485193040.032
sensory organ developmentGO:00074233930.032
regulation of primary metabolic processGO:00800903110.032
transportGO:00068102200.032
embryonic organ morphogenesisGO:00485622740.031
negative regulation of cellular processGO:00485232830.031
cellular response to external stimulusGO:007149620.031
response to stressGO:00069502630.031
Rat
regulation of nitrogen compound metabolic processGO:00511712510.030
nucleic acid metabolic processGO:00903042440.030
regulation of cell communicationGO:00106462320.030
lipid storageGO:001991510.030
nuclear transportGO:005116940.030
cellular protein catabolic processGO:004425740.029
adult behaviorGO:003053420.029
system processGO:00030081850.029
response to carbohydrateGO:000974330.029
modification dependent macromolecule catabolic processGO:004363230.028
heart developmentGO:00075073130.028
cell substrate adhesionGO:003158940.028
response to external stimulusGO:00096052640.027
Rat
nucleobase containing compound biosynthetic processGO:00346542050.027
Rat
neuron differentiationGO:00301823530.027
cell projection morphogenesisGO:00488582440.026
nucleocytoplasmic transportGO:000691340.026
cellular amine metabolic processGO:004410620.026
single organism transportGO:00447652060.026
cellular response to nutrient levelsGO:003166920.026
positive regulation of cellular processGO:00485222010.026
positive regulation of biological processGO:00485182530.025
cellular component morphogenesisGO:00329893360.025
regulation of biosynthetic processGO:00098892500.025
regulation of establishment of protein localizationGO:007020140.025
mitochondrion organizationGO:000700540.025
regulation of synaptic plasticityGO:004816710.025
embryo development ending in birth or egg hatchingGO:00097922710.025
regulation of signalingGO:00230512350.025
cell projection organizationGO:00300302840.024
regulation of nucleobase containing compound metabolic processGO:00192192500.024
protein metabolic processGO:00195381830.024
cytokinesisGO:000091030.024
establishment of localizationGO:00512342440.024
regulation of mrna processingGO:005068430.024
regulation of signal transductionGO:00099662250.024
regulation of cytoplasmic transportGO:190364940.023
regulation of intracellular protein transportGO:003315730.023
establishment of protein localization to organelleGO:007259440.023
regulation of dendrite developmentGO:005077330.023
positive regulation of cytosolic calcium ion concentrationGO:000720440.023
cellular component biogenesisGO:00440851780.023
cellular aromatic compound metabolic processGO:00067252950.023
Rat
macromolecule biosynthetic processGO:00090592270.023
positive regulation of catabolic processGO:000989640.023
tube morphogenesisGO:00352393490.023
proteolysis involved in cellular protein catabolic processGO:005160330.023
regulation of protein complex assemblyGO:004325430.023
cellular response to chemical stimulusGO:00708871570.023
regulation of metal ion transportGO:001095940.022
morphogenesis of an epitheliumGO:00020093330.022
organelle organizationGO:00069962270.022
regulation of cellular amine metabolic processGO:003323800.022
autophagyGO:000691440.022
proteasomal protein catabolic processGO:001049820.022
synaptic transmission cholinergicGO:000727140.022
protein polymerizationGO:005125840.022
cellular protein metabolic processGO:00442671290.022
neuron developmentGO:00486662620.021
localization of cellGO:00516742440.021
regulation of cell deathGO:00109411030.021
cell motilityGO:00488702440.021
amine metabolic processGO:000930820.021
response to organic substanceGO:00100331530.021
Rat
blood circulationGO:0008015870.021
carboxylic acid metabolic processGO:0019752220.021
Yeast Rat
axonogenesisGO:00074091520.021
regulation of tube sizeGO:003515020.021
muscle structure developmentGO:00610611960.021
striated muscle tissue developmentGO:00147061100.021
regulation of cellular amino acid metabolic processGO:000652100.021
sequestering of metal ionGO:005123830.021
regulation of anatomical structure morphogenesisGO:00226031300.021
organic acid metabolic processGO:0006082310.021
Yeast Rat
phosphate containing compound metabolic processGO:00067961080.020
Yeast Rat
directional locomotionGO:003305810.020
camera type eye developmentGO:00430102220.020
gtp metabolic processGO:004603940.020
cellular amino acid metabolic processGO:000652070.020
sequestering of calcium ionGO:005120830.020
regulation of muscle contractionGO:000693730.020
blood vessel developmentGO:00015682460.020
developmental growthGO:00485891660.020
Rat
regulation of synapse organizationGO:005080730.020
cellular ketone metabolic processGO:0042180110.020
i kappab kinase nf kappab signalingGO:000724940.020
regulation of cellular ketone metabolic processGO:001056570.020
small molecule metabolic processGO:0044281770.020
Yeast Rat
cellular component movementGO:00069283350.020
transcription dna templatedGO:00063511810.020
positive regulation of cellular component biogenesisGO:004408930.020
rna metabolic processGO:00160702190.020
synaptic vesicle transportGO:004848910.020
ion transportGO:00068111140.020
positive regulation of cellular catabolic processGO:003133130.020
protein localization to nucleusGO:003450430.020
regulation of cell developmentGO:00602841000.020
growthGO:00400071740.020
Rat
cell migrationGO:00164772370.020
sensory organ morphogenesisGO:00905962000.019
cell morphogenesisGO:00009022890.019
neurotransmitter secretionGO:000726920.019
muscle organ developmentGO:00075171010.019
protein targeting to nucleusGO:004474430.019
digestive tract developmentGO:00485652650.019
nucleic acid templated transcriptionGO:00976591810.019
neuron projection developmentGO:00311751800.019
regulation of sequestering of calcium ionGO:005128240.019
regulation of bindingGO:005109830.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
neurotransmitter transportGO:000683620.019
aromatic compound biosynthetic processGO:00194382170.019
Rat
rna biosynthetic processGO:00327741810.019
exocytosisGO:000688710.019
negative regulation of protein phosphorylationGO:000193340.019
single organism nuclear importGO:190259330.019
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.018
deathGO:00162651210.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
regulation of cytokine productionGO:000181730.018
oxoacid metabolic processGO:0043436310.018
Yeast Rat
blood vessel morphogenesisGO:00485142160.018
cell deathGO:00082191210.018
neuron projection morphogenesisGO:00488121610.018
positive regulation of cellular amine metabolic processGO:003324000.018
regulation of nucleic acid templated transcriptionGO:19035062130.018
response to monosaccharideGO:003428430.018
circulatory system processGO:0003013870.018
regulation of reproductive processGO:200024140.018
single organism metabolic processGO:00447102170.018
Yeast Rat
digestive tract morphogenesisGO:00485462310.018
nuclear importGO:005117030.018
extrinsic apoptotic signaling pathwayGO:009719130.018
digestive system developmentGO:00551232890.018
regulation of macromolecule biosynthetic processGO:00105562250.017
stem cell proliferationGO:007208940.017
cellular component assemblyGO:00226071700.017
negative regulation of protein kinase activityGO:000646940.017
negative regulation of kinase activityGO:003367340.017
gtp catabolic processGO:000618420.017
protein acylationGO:004354330.017
cellular carbohydrate metabolic processGO:004426240.017
protein importGO:001703830.017
protein import into nucleusGO:000660630.017
regulation of cell substrate adhesionGO:001081010.017
ubiquitin dependent protein catabolic processGO:000651130.017
muscle cell developmentGO:00550011150.017
programmed cell deathGO:00125011190.017
regulation of protein catabolic processGO:004217610.017
regulation of autophagyGO:001050630.017
modification dependent protein catabolic processGO:001994130.017
response to endogenous stimulusGO:0009719830.017
Rat
regulation of cellular macromolecule biosynthetic processGO:20001122220.017
multi organism processGO:00517041340.017
apoptotic processGO:00069151160.017
regulation of cell activationGO:005086510.017
response to hexoseGO:000974630.017
vasculature developmentGO:00019442780.017
regulation of apoptotic processGO:0042981980.016
regulation of cell shapeGO:000836010.016
regulation of dendrite morphogenesisGO:004881430.016
connective tissue developmentGO:0061448990.016
angiogenesisGO:00015251580.016
phosphorus metabolic processGO:00067931090.016
Yeast Rat
regulation of protein targetingGO:190353320.016
secondary metabolic processGO:001974830.016
central nervous system developmentGO:00074173870.016
guanosine containing compound metabolic processGO:190106840.016
regulation of blood vessel sizeGO:005088020.016
regulation of rna metabolic processGO:00512522240.016
regulation of nucleocytoplasmic transportGO:004682220.016
retina development in camera type eyeGO:00600411460.016
tissue remodelingGO:004877140.016
behaviorGO:0007610740.016
single organism organelle organizationGO:19025891990.016
meiotic cell cycle processGO:190304630.016
ion transmembrane transportGO:0034220910.016
axon developmentGO:00615641660.016
peptide metabolic processGO:000651810.016
protein localization to plasma membraneGO:007265910.016
heart contractionGO:0060047710.015
organelle fusionGO:004828430.015
carbohydrate homeostasisGO:003350010.015
guanosine containing compound catabolic processGO:190106920.015
synaptic vesicle localizationGO:009747910.015
striated muscle cell developmentGO:00550021080.015
wound healingGO:0042060900.015
Rat
regulation of programmed cell deathGO:00430671010.015
meiotic nuclear divisionGO:000712640.015
determination of left right symmetryGO:00073681790.015
gastrulationGO:00073692080.015
peptide transportGO:001583310.015
rna localizationGO:000640340.015
regionalizationGO:00030022740.015
gland developmentGO:00487321430.015
Rat
eye developmentGO:00016542770.015
superoxide metabolic processGO:000680120.015
muscle cell differentiationGO:00426921390.015
protein acetylationGO:000647320.015
cellular response to organic substanceGO:00713101050.014
determination of bilateral symmetryGO:00098552040.014
mitochondrial transportGO:000683920.014
regulation of skeletal muscle tissue developmentGO:004864140.014
muscle tissue developmentGO:00605371100.014
regulation of reactive oxygen species metabolic processGO:200037720.014
cellular response to oxygen levelsGO:007145310.014
response to corticosteroidGO:003196010.014
chordate embryonic developmentGO:00430092710.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
actin polymerization or depolymerizationGO:000815420.014
adherens junction organizationGO:003433240.014
synaptic growth at neuromuscular junctionGO:005112420.014
regulation of erk1 and erk2 cascadeGO:007037240.014
regulation of rna biosynthetic processGO:20011412130.014
cellular response to starvationGO:000926710.014
nuclear exportGO:005116810.014
heart processGO:0003015710.014
specification of symmetryGO:00097992040.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
regulation of calcium ion transportGO:005192420.014
organelle assemblyGO:00709251100.014
regulation of cell differentiationGO:00455951420.014
b cell activationGO:004211320.014
peptidyl serine modificationGO:001820920.014
cellular localizationGO:0051641970.014
positive regulation of blood circulationGO:190352420.014
protein dephosphorylationGO:000647030.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
negative regulation of catabolic processGO:000989530.014
positive regulation of cell adhesionGO:004578510.014
cellular protein modification processGO:00064641000.014
cell matrix adhesionGO:000716040.014
glucose homeostasisGO:004259310.014
cellular component assembly involved in morphogenesisGO:00109271070.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
membrane fusionGO:006102520.013
regulation of neurotransmitter secretionGO:004692810.013
regulation of neurogenesisGO:0050767870.013
head developmentGO:00603223030.013
hepaticobiliary system developmentGO:0061008980.013
Rat
organonitrogen compound metabolic processGO:1901564740.013
Rat
response to glucocorticoidGO:005138410.013
positive regulation of cytoskeleton organizationGO:005149530.013
regulation of neuron differentiationGO:0045664560.013
regulation of blood pressureGO:000821710.013
carbohydrate biosynthetic processGO:001605110.013
developmental growth involved in morphogenesisGO:0060560860.013
response to glucoseGO:000974930.013
establishment of synaptic vesicle localizationGO:009748010.013
regulation of localizationGO:00328791040.013
stem cell maintenanceGO:001982740.013
cartilage developmentGO:0051216960.013
positive regulation of protein complex assemblyGO:003133420.013
macromolecule modificationGO:00434121110.013
regulation of nucleoside metabolic processGO:000911820.013
regulation of neural precursor cell proliferationGO:200017730.013
phagocytosis engulfmentGO:000691110.013
neuroblast proliferationGO:000740520.013
positive regulation of secretion by cellGO:190353210.013
skeletal muscle tissue developmentGO:0007519670.013
cellular component disassemblyGO:002241110.013
response to alkaloidGO:004327920.013
cytoskeleton organizationGO:0007010960.013
positive regulation of cytokine productionGO:000181920.013
negative regulation of defense responseGO:003134820.013
regulation of purine nucleotide catabolic processGO:003312120.013
regulation of protein import into nucleusGO:004230620.013
response to amino acidGO:004320020.013
regulation of mrna splicing via spliceosomeGO:004802430.012
sensory system developmentGO:0048880760.012
regulation of transcription dna templatedGO:00063552130.012
negative regulation of signalingGO:0023057960.012
intracellular signal transductionGO:0035556850.012
ear developmentGO:00435831270.012
regulation of cellular biosynthetic processGO:00313262450.012
striated muscle cell differentiationGO:00511461290.012
g1 s transition of mitotic cell cycleGO:000008210.012
regulation of meiotic cell cycleGO:005144510.012
negative regulation of macromolecule metabolic processGO:0010605760.012
cellular response to extracellular stimulusGO:003166820.012
positive regulation of cellular metabolic processGO:0031325940.012
production of molecular mediator of immune responseGO:000244020.012
lateral line system developmentGO:0048925760.012
regulation of synapse assemblyGO:005196330.012
response to woundingGO:00096111160.012
Rat
dna templated transcription elongationGO:000635430.012
internal protein amino acid acetylationGO:000647520.012
cellular amide metabolic processGO:004360340.012
regulation of protein localization to nucleusGO:190018020.012
antimicrobial humoral responseGO:001973020.012
cell cycle g1 s phase transitionGO:004484310.012
regulation of gtp catabolic processGO:003312420.012
regulation of cellular component organizationGO:0051128860.012
response to external biotic stimulusGO:0043207970.012
cation homeostasisGO:0055080330.012
regulation of inflammatory responseGO:005072720.012
epithelial tube morphogenesisGO:00605621480.012
cell cycle arrestGO:000705010.012
regulation of neurotransmitter transportGO:005158810.012
negative regulation of metabolic processGO:0009892860.012
response to hydrogen peroxideGO:004254230.012
positive regulation of nucleoside metabolic processGO:004597910.012
actin filament based movementGO:003004810.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
regulation of jak stat cascadeGO:004642530.012
response to other organismGO:0051707970.012
response to uvGO:000941130.012
neuromuscular synaptic transmissionGO:000727420.012
fin morphogenesisGO:0033334530.012
transmembrane transportGO:00550851200.012
skeletal system developmentGO:00015011810.011
cellular response to biotic stimulusGO:007121630.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
ventricular cardiac muscle tissue developmentGO:000322930.011
peptidyl serine phosphorylationGO:001810510.011
regulation of protein polymerizationGO:003227120.011
peptidyl lysine acetylationGO:001839420.011
cellular macromolecule biosynthetic processGO:00346452240.011
spermatid developmentGO:000728620.011
membrane invaginationGO:001032410.011
retina morphogenesis in camera type eyeGO:0060042790.011
negative regulation of cellular catabolic processGO:003133030.011
female sex differentiationGO:004666040.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
protein modification processGO:00362111000.011
g protein coupled receptor signaling pathwayGO:0007186740.011
negative regulation of cell deathGO:0060548600.011
chemosensory behaviorGO:000763510.011
chemical homeostasisGO:0048878490.011
regulation of nervous system developmentGO:0051960900.011
ion homeostasisGO:0050801410.011
negative regulation of cytokine productionGO:000181810.011
macromolecular complex disassemblyGO:003298410.011
mesenchyme developmentGO:00604851270.011
reactive oxygen species metabolic processGO:007259360.011
sensory perception of chemical stimulusGO:000760630.011
regulation of protein bindingGO:004339330.011
cilium morphogenesisGO:0060271850.011
positive regulation of cell activationGO:005086710.011
leukocyte proliferationGO:007066110.011
post embryonic morphogenesisGO:000988640.011
negative regulation of programmed cell deathGO:0043069580.011
protein secretionGO:000930610.011
inorganic ion transmembrane transportGO:0098660570.011
ameboidal type cell migrationGO:00016671430.011
erk1 and erk2 cascadeGO:007037140.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
regulation of nucleotide catabolic processGO:003081120.011
positive regulation of macromolecule metabolic processGO:0010604930.011
regulation of stem cell proliferationGO:007209120.011
protein complex disassemblyGO:004324110.011
stem cell divisionGO:001714510.011
fin developmentGO:0033333770.011
protein stabilizationGO:005082120.011
cellular response to reactive oxygen speciesGO:003461420.011
tissue regenerationGO:0042246740.011
Rat
regulation of myotube differentiationGO:001083020.011
negative regulation of cell communicationGO:0010648960.011
nuclear migrationGO:000709730.011
positive regulation of secretionGO:005104710.010
positive regulation of i kappab kinase nf kappab signalingGO:004312330.010
regulation of stem cell differentiationGO:200073640.010
internal peptidyl lysine acetylationGO:001839320.010
hemopoiesisGO:00300971830.010
positive regulation of map kinase activityGO:004340630.010
regulation of i kappab kinase nf kappab signalingGO:004312240.010
cellular response to molecule of bacterial originGO:007121930.010
female gonad developmentGO:000858540.010
cellular response to hypoxiaGO:007145610.010
taxisGO:00423301090.010
cytoskeleton dependent cytokinesisGO:006164030.010
regulation of neuronal synaptic plasticityGO:004816810.010
positive regulation of jnk cascadeGO:004633030.010
regulation of cellular carbohydrate metabolic processGO:001067540.010
development of primary female sexual characteristicsGO:004654540.010
notochord developmentGO:0030903540.010
small molecule catabolic processGO:004428230.010

pkm2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.105
nervous system diseaseDOID:86300.023
musculoskeletal system diseaseDOID:1700.021
immune system diseaseDOID:291400.017
muscular diseaseDOID:008000000.015
muscle tissue diseaseDOID:6600.015
disease of metabolismDOID:001466700.014
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
cancerDOID:16200.012
cardiovascular system diseaseDOID:128700.010