Danio rerio

0 known processes

klhl18

kelch-like 18 (Drosophila)

(Aliases: zgc:55359,wu:fi18c08)

klhl18 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.137
modification dependent protein catabolic processGO:001994130.135
cell projection morphogenesisGO:00488582440.111
neuron differentiationGO:00301823530.107
larval developmentGO:000216420.085
signal transductionGO:00071654550.084
Zebrafish
locomotionGO:00400113130.081
cellular macromolecule biosynthetic processGO:00346452240.081
embryo development ending in birth or egg hatchingGO:00097922710.080
regulation of signalingGO:00230512350.079
cellular component morphogenesisGO:00329893360.070
regulation of cellular metabolic processGO:00313233200.070
organonitrogen compound metabolic processGO:1901564740.070
heterocycle biosynthetic processGO:00181302150.068
chordate embryonic developmentGO:00430092710.066
cellular component movementGO:00069283350.066
single organism organelle organizationGO:19025891990.065
cell projection organizationGO:00300302840.065
neuron developmentGO:00486662620.064
regulation of signal transductionGO:00099662250.064
cell part morphogenesisGO:00329902460.064
regulation of metabolic processGO:00192223590.060
regulation of cell communicationGO:00106462320.058
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.057
cell morphogenesisGO:00009022890.057
modification dependent macromolecule catabolic processGO:004363230.057
generation of neuronsGO:00486993850.055
cellular response to chemical stimulusGO:00708871570.055
regulation of macromolecule metabolic processGO:00602553170.054
maintenance of locationGO:005123540.054
cellular protein catabolic processGO:004425740.053
sensory organ developmentGO:00074233930.053
proteolysis involved in cellular protein catabolic processGO:005160330.053
transportGO:00068102200.053
nitrogen compound metabolic processGO:00068073190.052
cellular macromolecule metabolic processGO:00442603910.052
transcription from rna polymerase ii promoterGO:0006366800.052
neuron projection morphogenesisGO:00488121610.051
cytokinesisGO:000091030.049
response to chemicalGO:00422213200.049
neuron projection developmentGO:00311751800.048
axon developmentGO:00615641660.047
response to stressGO:00069502630.046
axonogenesisGO:00074091520.046
nucleobase containing compound biosynthetic processGO:00346542050.045
protein metabolic processGO:00195381830.045
adult behaviorGO:003053420.045
aromatic compound biosynthetic processGO:00194382170.045
heterocycle metabolic processGO:00464832900.045
cellular response to external stimulusGO:007149620.043
organic substance biosynthetic processGO:19015762890.042
positive regulation of cell cycleGO:004578730.042
single organism metabolic processGO:00447102170.042
regulation of transcription dna templatedGO:00063552130.041
enzyme linked receptor protein signaling pathwayGO:00071671060.040
small molecule metabolic processGO:0044281770.040
phagocytosisGO:000690930.040
amine metabolic processGO:000930820.040
tube morphogenesisGO:00352393490.039
protein localization to plasma membraneGO:007265910.039
cellular component biogenesisGO:00440851780.039
skeletal system developmentGO:00015011810.039
protein localization to nucleusGO:003450430.038
single organism transportGO:00447652060.038
lipid storageGO:001991510.038
positive regulation of transportGO:005105020.038
regulation of developmental processGO:00507932470.038
cell surface receptor signaling pathwayGO:00071663250.038
Zebrafish
cellular biosynthetic processGO:00442492860.037
single organism localizationGO:19025782250.037
regulation of transcription from rna polymerase ii promoterGO:00063571140.036
hormone transportGO:000991420.036
multicellular organism growthGO:003526440.036
cellular amine metabolic processGO:004410620.036
extrinsic apoptotic signaling pathwayGO:009719130.035
positive regulation of cellular processGO:00485222010.035
regionalizationGO:00030022740.035
Zebrafish
establishment of protein localization to organelleGO:007259440.035
nuclear transportGO:005116940.035
positive regulation of map kinase activityGO:004340630.035
positive regulation of biological processGO:00485182530.035
regulation of cellular ketone metabolic processGO:001056570.035
gtp metabolic processGO:004603940.035
gtp catabolic processGO:000618420.035
regulation of establishment of protein localizationGO:007020140.035
guanosine containing compound catabolic processGO:190106920.035
cellular amino acid metabolic processGO:000652070.034
proteasomal protein catabolic processGO:001049820.034
positive regulation of cellular catabolic processGO:003133130.034
peptide transportGO:001583310.034
organic cyclic compound biosynthetic processGO:19013622230.034
response to organic substanceGO:00100331530.034
stem cell proliferationGO:007208940.033
system processGO:00030081850.033
regulation of cellular amino acid metabolic processGO:000652100.033
cellular response to nutrient levelsGO:003166920.033
cellular nitrogen compound metabolic processGO:00346412900.033
cellular nitrogen compound biosynthetic processGO:00442712180.032
transcription dna templatedGO:00063511810.032
regulation of extrinsic apoptotic signaling pathwayGO:200123630.032
single organism nuclear importGO:190259330.032
golgi vesicle transportGO:004819330.032
brain developmentGO:00074202930.032
nucleic acid templated transcriptionGO:00976591810.031
heart developmentGO:00075073130.031
regulation of nucleobase containing compound metabolic processGO:00192192500.031
gene expressionGO:00104672520.031
cellular ketone metabolic processGO:0042180110.031
heart morphogenesisGO:00030071560.031
regulation of response to stimulusGO:00485832690.031
embryonic organ developmentGO:00485683810.030
stem cell maintenanceGO:001982740.030
regulation of nitrogen compound metabolic processGO:00511712510.030
regulation of multicellular organism growthGO:004001440.030
cellular aromatic compound metabolic processGO:00067252950.029
centrosome cycleGO:000709810.029
negative regulation of protein phosphorylationGO:000193340.029
negative regulation of kinase activityGO:003367340.029
localization of cellGO:00516742440.029
positive regulation of nitrogen compound metabolic processGO:0051173690.029
negative regulation of signal transductionGO:0009968940.029
cell migrationGO:00164772370.029
regulation of primary metabolic processGO:00800903110.029
protein modification processGO:00362111000.029
morphogenesis of an epitheliumGO:00020093330.029
Zebrafish
negative regulation of biological processGO:00485193040.028
macromolecule glycosylationGO:004341390.028
negative regulation of signalingGO:0023057960.028
regulation of circadian rhythmGO:004275240.028
negative regulation of response to stimulusGO:00485851040.028
regulation of nucleic acid templated transcriptionGO:19035062130.028
phagocytosis engulfmentGO:000691110.028
cell motilityGO:00488702440.028
regulation of cellular amine metabolic processGO:003323800.027
regulation of biosynthetic processGO:00098892500.027
centrosome organizationGO:005129710.027
establishment of localizationGO:00512342440.027
mitotic dna integrity checkpointGO:004477440.027
macromolecule biosynthetic processGO:00090592270.027
connective tissue developmentGO:0061448990.027
cell morphogenesis involved in neuron differentiationGO:00486671630.026
intracellular signal transductionGO:0035556850.026
developmental maturationGO:0021700340.026
cell agingGO:000756920.026
taxisGO:00423301090.026
positive regulation of striated muscle tissue developmentGO:004584410.026
negative regulation of cell communicationGO:0010648960.026
guanosine containing compound metabolic processGO:190106840.026
ubiquitin dependent protein catabolic processGO:000651130.026
cellular protein modification processGO:00064641000.026
protein targeting to nucleusGO:004474430.026
positive regulation of muscle tissue developmentGO:190186310.025
nucleocytoplasmic transportGO:000691340.025
negative regulation of tor signalingGO:003200720.025
positive regulation of purine nucleotide catabolic processGO:003312310.025
centrosome duplicationGO:005129810.025
cellular response to extracellular stimulusGO:003166820.025
apoptotic processGO:00069151160.025
regulation of biological qualityGO:00650082630.025
organic cyclic compound metabolic processGO:19013603010.025
positive regulation of catabolic processGO:000989640.024
organic acid metabolic processGO:0006082310.024
microtubule organizing center organizationGO:003102310.024
positive regulation of cell adhesionGO:004578510.024
negative regulation of protein kinase activityGO:000646940.024
regulation of protein catabolic processGO:004217610.024
embryonic organ morphogenesisGO:00485622740.024
rna biosynthetic processGO:00327741810.024
cell deathGO:00082191210.023
gland developmentGO:00487321430.023
regulation of protein transportGO:005122330.023
rna localizationGO:000640340.023
response to topologically incorrect proteinGO:003596620.023
cellular protein metabolic processGO:00442671290.023
hepaticobiliary system developmentGO:0061008980.023
regulation of nucleoside metabolic processGO:000911820.023
membrane invaginationGO:001032410.023
response to external stimulusGO:00096052640.023
regulation of rna biosynthetic processGO:20011412130.022
cellular response to starvationGO:000926710.022
regulation of cellular macromolecule biosynthetic processGO:20001122220.022
liver developmentGO:0001889960.022
spindle assemblyGO:005122520.022
oxoacid metabolic processGO:0043436310.022
striated muscle tissue developmentGO:00147061100.022
positive regulation of cellular amine metabolic processGO:003324000.022
adherens junction organizationGO:003433240.022
regulation of peptidyl tyrosine phosphorylationGO:005073010.022
positive regulation of nucleoside metabolic processGO:004597910.022
autophagyGO:000691440.021
positive regulation of jun kinase activityGO:004350720.021
protein import into nucleusGO:000660630.021
immune system processGO:00023762410.021
cell morphogenesis involved in differentiationGO:00009041950.021
biosynthetic processGO:00090582940.021
mitotic g2 m transition checkpointGO:004481830.021
nuclear importGO:005117030.021
sleepGO:003043110.021
pronuclear migrationGO:003504610.020
positive regulation of macromolecule biosynthetic processGO:0010557590.020
nucleobase containing compound metabolic processGO:00061392740.020
cellular component assemblyGO:00226071700.020
positive regulation of apoptotic signaling pathwayGO:200123510.020
cytoskeleton organizationGO:0007010960.019
protein importGO:001703830.019
eye developmentGO:00016542770.019
regulation of response to extracellular stimulusGO:003210410.019
rna metabolic processGO:00160702190.019
organelle organizationGO:00069962270.019
chemotaxisGO:00069351040.019
protein secretionGO:000930610.019
regulation of apoptotic processGO:0042981980.019
negative regulation of cellular catabolic processGO:003133030.019
cytoskeleton dependent cytokinesisGO:006164030.019
regulation of cellular biosynthetic processGO:00313262450.019
behaviorGO:0007610740.019
ribonucleoside monophosphate catabolic processGO:000915840.019
response to woundingGO:00096111160.019
locomotor rhythmGO:004547530.019
nucleic acid metabolic processGO:00903042440.019
macromolecule modificationGO:00434121110.018
convergent extensionGO:00600261180.018
Zebrafish
regulation of wound healingGO:006104120.018
regulation of cytoplasmic transportGO:190364940.018
regulation of protein targetingGO:190353320.018
response to xenobiotic stimulusGO:0009410450.018
cellular carbohydrate metabolic processGO:004426240.018
regulation of hormone secretionGO:004688320.018
negative regulation of catabolic processGO:000989530.018
response to drugGO:004249330.018
cell cycle g1 s phase transitionGO:004484310.018
regulation of cell cycleGO:0051726520.018
regulation of protein complex assemblyGO:004325430.018
muscle structure developmentGO:00610611960.018
regulation of meiotic cell cycleGO:005144510.018
regulation of bindingGO:005109830.018
protein stabilizationGO:005082120.017
synaptic growth at neuromuscular junctionGO:005112420.017
germ line stem cell maintenanceGO:003071820.017
regulation of organ growthGO:004662030.017
forebrain cell migrationGO:002188510.017
regulation of dendrite developmentGO:005077330.017
regulation of rho protein signal transductionGO:003502320.017
negative regulation of multicellular organismal processGO:0051241690.017
ras protein signal transductionGO:000726570.017
response to nutrientGO:000758430.017
endosomal transportGO:001619720.017
central nervous system developmentGO:00074173870.017
negative regulation of metabolic processGO:0009892860.017
regulation of anatomical structure morphogenesisGO:00226031300.017
positive regulation of signalingGO:0023056560.017
protein homooligomerizationGO:005126030.016
type b pancreatic cell developmentGO:000332340.016
carboxylic acid metabolic processGO:0019752220.016
small gtpase mediated signal transductionGO:000726480.016
cellular component disassemblyGO:002241110.016
blood vessel developmentGO:00015682460.016
regulation of nucleotide catabolic processGO:003081120.016
negative regulation of histone modificationGO:003105710.016
positive regulation of cellular component biogenesisGO:004408930.016
cellular amide metabolic processGO:004360340.016
regulation of multicellular organismal processGO:00512392770.016
compound eye developmentGO:004874920.016
axon guidanceGO:0007411860.016
regulation of autophagyGO:001050630.016
response to hexoseGO:000974630.016
establishment of protein localization to plasma membraneGO:009000210.015
regulation of stem cell proliferationGO:007209120.015
regulation of response to nutrient levelsGO:003210710.015
cellular component assembly involved in morphogenesisGO:00109271070.015
positive regulation of cellular biosynthetic processGO:0031328680.015
multi organism processGO:00517041340.015
positive regulation of nucleotide catabolic processGO:003081310.015
forebrain developmentGO:0030900960.015
regulation of rna metabolic processGO:00512522240.015
positive regulation of muscle organ developmentGO:004863610.015
cellular response to biotic stimulusGO:007121630.015
regulation of skeletal muscle tissue developmentGO:004864140.015
neuroblast proliferationGO:000740520.015
meiotic nuclear divisionGO:000712640.015
cellular response to organic substanceGO:00713101050.015
organelle assemblyGO:00709251100.015
nucleoside monophosphate catabolic processGO:000912540.015
positive regulation of secretionGO:005104710.015
regulation of gene expressionGO:00104682650.015
digestive tract developmentGO:00485652650.015
hypothalamus cell differentiationGO:002197940.015
hormone secretionGO:004687920.015
positive regulation of wound healingGO:009030310.015
positive regulation of protein complex assemblyGO:003133420.015
regulation of cell developmentGO:00602841000.015
positive regulation of cellular amino acid metabolic processGO:004576400.014
homeostatic processGO:00425921420.014
antimicrobial humoral responseGO:001973020.014
stem cell divisionGO:001714510.014
regulation of gtp catabolic processGO:003312420.014
phosphorus metabolic processGO:00067931090.014
meiotic cell cycle processGO:190304630.014
positive regulation of gtpase activityGO:004354710.014
rna transportGO:005065820.014
regulation of protein metabolic processGO:0051246560.014
epithelial cell differentiationGO:00308551160.014
regulation of neurogenesisGO:0050767870.014
vacuolar transportGO:000703420.014
actin filament polymerizationGO:003004120.014
forebrain regionalizationGO:002187140.014
positive regulation of cell communicationGO:0010647560.014
negative regulation of catalytic activityGO:0043086210.014
circadian sleep wake cycle sleepGO:005080210.014
heart contractionGO:0060047710.014
regulation of protein localization to nucleusGO:190018020.014
regulation of synaptic plasticityGO:004816710.014
oxidative phosphorylationGO:000611910.014
regulation of molecular functionGO:0065009700.014
stem cell differentiationGO:00488631170.014
regulation of reactive oxygen species metabolic processGO:200037720.014
eye morphogenesisGO:00485921440.013
regulation of localizationGO:00328791040.013
regulation of cell deathGO:00109411030.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
actin polymerization or depolymerizationGO:000815420.013
embryonic cranial skeleton morphogenesisGO:0048701900.013
lateral inhibitionGO:004633110.013
ear developmentGO:00435831270.013
actin cytoskeleton organizationGO:0030036630.013
positive regulation of canonical wnt signaling pathwayGO:009026340.013
positive regulation of cell substrate adhesionGO:001081110.013
convergent extension involved in gastrulationGO:0060027710.013
regulation of dendrite morphogenesisGO:004881430.013
vasculature developmentGO:00019442780.013
muscle tissue developmentGO:00605371100.013
positive regulation of secretion by cellGO:190353210.013
carbohydrate derivative metabolic processGO:1901135610.013
cartilage developmentGO:0051216960.013
production of molecular mediator of immune responseGO:000244020.013
cortical actin cytoskeleton organizationGO:003086610.013
wnt signaling pathwayGO:0016055800.013
Zebrafish
cellular respirationGO:004533330.013
cell matrix adhesionGO:000716040.013
g1 s transition of mitotic cell cycleGO:000008210.013
positive regulation of immune effector processGO:000269930.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
glucose homeostasisGO:004259310.013
synaptic vesicle transportGO:004848910.013
negative regulation of immune responseGO:005077720.013
regulation of cell shapeGO:000836010.013
regulation of protein polymerizationGO:003227120.013
activation of mapk activityGO:000018730.013
protein glycosylationGO:000648690.013
g2 dna damage checkpointGO:003157230.013
regulation of macromolecule biosynthetic processGO:00105562250.013
regulation of erk1 and erk2 cascadeGO:007037240.013
internal peptidyl lysine acetylationGO:001839320.013
positive regulation of notch signaling pathwayGO:004574730.012
proteolysisGO:0006508380.012
regulation of cytokine productionGO:000181730.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
peptidyl serine phosphorylationGO:001810510.012
cognitionGO:005089010.012
rho protein signal transductionGO:000726650.012
cell substrate adhesionGO:003158940.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
positive regulation of gtp catabolic processGO:003312610.012
epithelial tube morphogenesisGO:00605621480.012
response to biotic stimulusGO:0009607970.012
glucose importGO:004632320.012
regulation of cellular component sizeGO:0032535300.012
regulation of multicellular organismal developmentGO:20000262230.012
regulation of reproductive processGO:200024140.012
macroautophagyGO:001623610.012
negative regulation of chromosome organizationGO:200125110.012
response to abiotic stimulusGO:00096281220.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
head developmentGO:00603223030.012
regulation of cellular component organizationGO:0051128860.012
cellular localizationGO:0051641970.012
protein acylationGO:004354330.012
stem cell developmentGO:0048864820.012
gastrulationGO:00073692080.012
negative regulation of cytokine productionGO:000181810.012
regulation of neural precursor cell proliferationGO:200017730.012
negative regulation of defense responseGO:003134820.012
establishment of synaptic vesicle localizationGO:009748010.012
cellular response to lipopolysaccharideGO:007122230.012
positive regulation of signal transductionGO:0009967560.012
positive regulation of stress activated mapk cascadeGO:003287430.012
erk1 and erk2 cascadeGO:007037140.012
neuron projection guidanceGO:0097485860.012
determination of bilateral symmetryGO:00098552040.012
dna templated transcription initiationGO:000635210.012
carbohydrate homeostasisGO:003350010.012
regulation of blood pressureGO:000821710.012
neurological system processGO:0050877620.012
regulation of purine nucleotide catabolic processGO:003312120.012
cellular response to molecule of bacterial originGO:007121930.012
positive regulation of metabolic processGO:00098931080.012
response to endogenous stimulusGO:0009719830.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
cortical cytoskeleton organizationGO:003086510.012
peptide metabolic processGO:000651810.012
phosphorylationGO:0016310690.012
regulation of protein import into nucleusGO:004230620.012
negative regulation of mapk cascadeGO:004340940.012
positive regulation of chromatin modificationGO:190331010.012
nucleic acid transportGO:005065720.011
inorganic anion transportGO:0015698250.011
regulation of cellular extravasationGO:000269110.011
cellular response to topologically incorrect proteinGO:003596720.011
protein complex assemblyGO:0006461300.011
negative regulation of cellular metabolic processGO:0031324770.011
macromolecular complex subunit organizationGO:0043933740.011
sensory organ morphogenesisGO:00905962000.011
regulation of oocyte developmentGO:006028130.011
biological adhesionGO:0022610400.011
single fertilizationGO:000733830.011
regulation of protein ubiquitinationGO:003139630.011
cell fate commitmentGO:0045165990.011
intracellular mrna localizationGO:000829810.011
regulation of ras gtpase activityGO:003231820.011
spermatid developmentGO:000728620.011
mitochondrion organizationGO:000700540.011
i kappab kinase nf kappab signalingGO:000724940.011
ameboidal type cell migrationGO:00016671430.011
circadian sleep wake cycle processGO:002241020.011
regulation of gtpase activityGO:004308720.011
nuclear envelope organizationGO:000699820.011
negative regulation of developmental processGO:0051093650.011
regulation of response to biotic stimulusGO:000283120.011
digestive system developmentGO:00551232890.011
mitotic dna damage checkpointGO:004477340.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
transmission of nerve impulseGO:0019226190.011
cell projection assemblyGO:0030031640.011
regulation of cell substrate adhesionGO:001081010.011
nuclear exportGO:005116810.011
regulation of cell differentiationGO:00455951420.011
pronephros developmentGO:0048793690.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
pigmentationGO:0043473850.011
regulation of rho gtpase activityGO:003231910.011
sensory perception of painGO:001923310.010
macromolecular complex disassemblyGO:003298410.010
negative regulation of protein import into nucleusGO:004230820.010
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.010
columnar cuboidal epithelial cell differentiationGO:0002065380.010
purine nucleoside monophosphate catabolic processGO:000912840.010
developmental growthGO:00485891660.010
Zebrafish
positive regulation of cellular metabolic processGO:0031325940.010
neuron neuron synaptic transmissionGO:000727010.010
intracellular receptor signaling pathwayGO:0030522300.010
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.010
regulation of synapse organizationGO:005080730.010
muscle organ developmentGO:00075171010.010
gas transportGO:001566930.010
er nucleus signaling pathwayGO:000698420.010
deathGO:00162651210.010
cell cycleGO:0007049930.010
response to oxygen levelsGO:0070482250.010
negative regulation of translationGO:001714810.010
regulation of jak stat cascadeGO:004642530.010
inner ear developmentGO:00488391260.010
cellular response to endogenous stimulusGO:0071495680.010
regulation of response to cytokine stimulusGO:006075930.010
positive regulation of myeloid cell differentiationGO:004563920.010
cell cycle arrestGO:000705010.010
specification of symmetryGO:00097992040.010

klhl18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.018
organ system cancerDOID:005068600.014
cancerDOID:16200.014
disease of cellular proliferationDOID:1456600.014
eye diseaseDOID:561400.011
eye and adnexa diseaseDOID:149200.011
sensory system diseaseDOID:005015500.011