Danio rerio

13 known processes

copa

coatomer protein complex, subunit alpha

(Aliases: fb13c12,wu:fb13c12,cb281)

copa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
er to golgi vesicle mediated transportGO:000688810.969
Yeast
locomotionGO:00400113130.865
Worm
larval developmentGO:000216420.834
Worm
embryonic organ developmentGO:00485683810.617
transportGO:00068102200.570
Human Yeast Worm Fly
single organism transportGO:00447652060.566
Human Yeast Worm Fly
protein n linked glycosylationGO:000648710.527
cell morphogenesisGO:00009022890.477
Fly
single organism localizationGO:19025782250.474
Human Yeast Worm Fly
protein glycosylationGO:000648690.467
meiotic cell cycle processGO:190304630.460
Fly
phagocytosisGO:000690930.450
Fly
establishment of localizationGO:00512342440.449
Human Yeast Worm Fly
establishment of localization in cellGO:0051649770.437
Yeast Worm
regulation of response to stimulusGO:00485832690.436
glycoprotein metabolic processGO:0009100230.403
positive regulation of innate immune responseGO:004508980.351
golgi vesicle transportGO:004819330.349
Yeast
protein localizationGO:0008104400.340
cellular component morphogenesisGO:00329893360.317
Fly
glycoprotein biosynthetic processGO:0009101210.285
single organism intracellular transportGO:1902582250.281
Yeast
notochord developmentGO:0030903540.266
carbohydrate derivative metabolic processGO:1901135610.259
maintenance of locationGO:005123540.258
Fly
positive regulation of biological processGO:00485182530.255
glycosylationGO:0070085110.242
meiotic nuclear divisionGO:000712640.233
cellular localizationGO:0051641970.222
Yeast Worm
protein secretionGO:000930610.218
lipid storageGO:001991510.216
Fly
carbohydrate derivative biosynthetic processGO:1901137430.216
apoptotic processGO:00069151160.214
Worm
embryo development ending in birth or egg hatchingGO:00097922710.214
Worm
central nervous system developmentGO:00074173870.213
organic substance transportGO:0071702580.213
cellular macromolecule metabolic processGO:00442603910.207
vasculature developmentGO:00019442780.178
negative regulation of cellular processGO:00485232830.176
response to external stimulusGO:00096052640.163
regulation of biological qualityGO:00650082630.157
Human Fly
cell migrationGO:00164772370.150
deathGO:00162651210.135
Worm
aromatic compound biosynthetic processGO:00194382170.133
cell projection morphogenesisGO:00488582440.130
Fly
cell deathGO:00082191210.130
Worm
single organism carbohydrate metabolic processGO:0044723120.129
ubiquitin dependent protein catabolic processGO:000651130.126
cellular component movementGO:00069283350.125
cell cycle processGO:0022402530.120
Fly
organic substance biosynthetic processGO:19015762890.119
head developmentGO:00603223030.118
regulation of cell morphogenesisGO:0022604420.114
cell motilityGO:00488702440.107
response to stressGO:00069502630.106
chordate embryonic developmentGO:00430092710.104
axonogenesisGO:00074091520.101
positive regulation of cellular processGO:00485222010.101
digestive tract morphogenesisGO:00485462310.100
macromolecule glycosylationGO:004341390.099
mitotic cytokinesisGO:000028130.099
regulation of response to stressGO:0080134360.098
response to bacteriumGO:0009617580.098
regulation of localizationGO:00328791040.097
Fly
cellular response to external stimulusGO:007149620.096
macromolecule localizationGO:0033036540.094
Fly
positive regulation of catabolic processGO:000989640.093
immune system processGO:00023762410.093
regulation of protein transportGO:005122330.092
agingGO:000756820.092
response to chemicalGO:00422213200.091
metal ion transportGO:0030001580.090
regulation of anatomical structure morphogenesisGO:00226031300.089
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.088
cell morphogenesis involved in differentiationGO:00009041950.086
neuron developmentGO:00486662620.085
Fly
eye developmentGO:00016542770.084
regulation of signalingGO:00230512350.083
regulation of developmental processGO:00507932470.083
modification dependent protein catabolic processGO:001994130.083
cell surface receptor signaling pathwayGO:00071663250.081
sensory organ developmentGO:00074233930.081
brain developmentGO:00074202930.080
regulation of innate immune responseGO:0045088110.079
neuron projection morphogenesisGO:00488121610.078
Fly
regulation of establishment of protein localizationGO:007020140.076
neuron projection developmentGO:00311751800.076
Fly
cellular protein modification processGO:00064641000.074
cellular component biogenesisGO:00440851780.073
positive regulation of cellular catabolic processGO:003133130.073
cellular biosynthetic processGO:00442492860.073
vesicle mediated transportGO:0016192220.072
Yeast Fly
regulation of intracellular protein transportGO:003315730.072
regulation of multicellular organismal processGO:00512392770.072
cellular response to topologically incorrect proteinGO:003596720.069
positive regulation of response to stimulusGO:0048584800.068
cell projection organizationGO:00300302840.068
Fly
small molecule metabolic processGO:0044281770.068
regulation of metabolic processGO:00192223590.067
axon developmentGO:00615641660.065
modification dependent macromolecule catabolic processGO:004363230.063
protein targeting to nucleusGO:004474430.062
regulation of nucleocytoplasmic transportGO:004682220.062
cell morphogenesis involved in neuron differentiationGO:00486671630.061
extracellular matrix organizationGO:0030198270.061
regulation of cell shapeGO:000836010.061
defense response to bacteriumGO:0042742220.060
nucleobase containing small molecule metabolic processGO:0055086320.060
regulation of protein catabolic processGO:004217610.060
localization of cellGO:00516742440.060
adult behaviorGO:003053420.058
embryonic skeletal system developmentGO:0048706970.058
cellular response to nutrient levelsGO:003166920.058
positive regulation of defense responseGO:003134990.057
signal transductionGO:00071654550.057
regulation of protein localization to nucleusGO:190018020.057
extracellular structure organizationGO:0043062270.057
taxisGO:00423301090.057
cell part morphogenesisGO:00329902460.056
Fly
protein localization to nucleusGO:003450430.056
hatchingGO:003518840.056
hindbrain developmentGO:0030902910.055
programmed cell deathGO:00125011190.054
Worm
anterior posterior pattern specificationGO:00099521520.054
protein importGO:001703830.054
response to metal ionGO:0010038340.053
positive regulation of immune responseGO:0050778110.053
intracellular transportGO:0046907320.052
Yeast
reproductionGO:0000003400.052
Worm Fly
ion transportGO:00068111140.051
regulation of macromolecule metabolic processGO:00602553170.051
neuron differentiationGO:00301823530.050
Fly
cellular nitrogen compound metabolic processGO:00346412900.050
oxoacid metabolic processGO:0043436310.050
heterocycle biosynthetic processGO:00181302150.049
cytoplasmic transportGO:0016482110.049
Yeast
establishment of protein localization to organelleGO:007259440.048
immune responseGO:0006955280.048
meiotic cell cycleGO:005132150.047
Fly
negative regulation of biological processGO:00485193040.047
protein import into nucleusGO:000660630.046
cellular protein catabolic processGO:004425740.046
skin developmentGO:0043588540.044
nitrogen compound metabolic processGO:00068073190.044
mesenchyme developmentGO:00604851270.044
collagen fibril organizationGO:003019910.043
endocytosisGO:0006897160.043
Fly
regulation of nucleic acid templated transcriptionGO:19035062130.043
lipid localizationGO:0010876110.043
Fly
endosomal transportGO:001619720.042
positive regulation of cellular component biogenesisGO:004408930.042
negative regulation of response to stimulusGO:00485851040.042
cation transportGO:0006812810.042
single organism metabolic processGO:00447102170.042
positive regulation of transportGO:005105020.041
negative regulation of cytoplasmic transportGO:190365020.041
cellular macromolecule biosynthetic processGO:00346452240.041
carbohydrate metabolic processGO:0005975120.041
cellular cation homeostasisGO:0030003170.041
epithelial cell morphogenesisGO:000338220.039
rna localizationGO:000640340.039
basement membrane assemblyGO:007083130.039
positive regulation of signalingGO:0023056560.039
toxin transportGO:190199820.039
cognitionGO:005089010.039
appendage developmentGO:0048736800.039
protein metabolic processGO:00195381830.039
defense response to gram negative bacteriumGO:005082980.038
protein heterooligomerizationGO:005129110.038
organonitrogen compound metabolic processGO:1901564740.038
regulation of multicellular organismal developmentGO:20000262230.038
camera type eye developmentGO:00430102220.038
multi organism cellular processGO:004476420.037
tube morphogenesisGO:00352393490.037
convergent extensionGO:00600261180.037
regulation of transportGO:0051049450.037
nucleobase containing compound biosynthetic processGO:00346542050.037
rna metabolic processGO:00160702190.037
regulation of primary metabolic processGO:00800903110.036
defense response to other organismGO:0098542330.036
retina development in camera type eyeGO:00600411460.036
defense responseGO:0006952470.036
embryonic organ morphogenesisGO:00485622740.036
cellular macromolecule localizationGO:0070727210.035
cellular component assemblyGO:00226071700.035
regulation of cytoplasmic transportGO:190364940.035
cellular amino acid metabolic processGO:000652070.035
forebrain developmentGO:0030900960.035
appendage morphogenesisGO:0035107560.035
nuclear importGO:005117030.035
skin morphogenesisGO:004358970.035
nuclear divisionGO:0000280230.035
epithelial cell differentiationGO:00308551160.034
response to external biotic stimulusGO:0043207970.034
regulation of cellular protein catabolic processGO:190336210.034
nucleobase containing compound metabolic processGO:00061392740.033
proteolysis involved in cellular protein catabolic processGO:005160330.033
regulation of protein import into nucleusGO:004230620.033
fin developmentGO:0033333770.033
regulation of axonogenesisGO:0050770320.032
organic acid metabolic processGO:0006082310.032
autophagyGO:000691440.032
neuroblast proliferationGO:000740520.032
visual behaviorGO:0007632100.032
regulation of signal transductionGO:00099662250.031
blood vessel morphogenesisGO:00485142160.031
regulation of immune responseGO:0050776140.031
exocytosisGO:000688710.031
er nucleus signaling pathwayGO:000698420.031
endomembrane system organizationGO:0010256130.031
phagocytosis engulfmentGO:000691110.031
organelle localizationGO:0051640490.031
negative regulation of small gtpase mediated signal transductionGO:005105810.031
regulation of cellular amine metabolic processGO:003323800.031
detection of visible lightGO:0009584120.030
intracellular mrna localizationGO:000829810.030
nucleotide metabolic processGO:0009117280.030
cellular response to chemical stimulusGO:00708871570.030
amine metabolic processGO:000930820.030
embryonic neurocranium morphogenesisGO:0048702150.030
ameboidal type cell migrationGO:00016671430.030
single organism cellular localizationGO:1902580460.029
cellular amide metabolic processGO:004360340.029
liver developmentGO:0001889960.029
regulation of immune system processGO:0002682340.029
regulation of protein metabolic processGO:0051246560.029
canonical wnt signaling pathwayGO:0060070480.029
single organism organelle organizationGO:19025891990.029
phosphate containing compound metabolic processGO:00067961080.029
developmental growth involved in morphogenesisGO:0060560860.028
response to biotic stimulusGO:0009607970.028
determination of left right symmetryGO:00073681790.028
cellular protein localizationGO:0034613200.028
fertilizationGO:000956630.028
regulation of synaptic growth at neuromuscular junctionGO:000858210.027
nucleocytoplasmic transportGO:000691340.027
multicellular organism growthGO:003526440.027
divalent inorganic cation homeostasisGO:0072507220.027
regulation of cellular biosynthetic processGO:00313262450.027
regulation of protein complex assemblyGO:004325430.027
mesenchymal cell developmentGO:0014031780.027
cellular component assembly involved in morphogenesisGO:00109271070.026
pole plasm assemblyGO:000731540.026
single organism biosynthetic processGO:0044711710.026
cellular response to extracellular stimulusGO:003166820.026
synaptic transmissionGO:0007268350.026
gland developmentGO:00487321430.025
positive regulation of chromosome organizationGO:200125210.025
activation of mapkkk activityGO:000018510.025
behaviorGO:0007610740.025
response to woundingGO:00096111160.025
synaptic growth at neuromuscular junctionGO:005112420.025
organism emergence from protective structureGO:007168440.024
dorsal ventral pattern formationGO:00099531250.024
regulation of cell communicationGO:00106462320.024
post golgi vesicle mediated transportGO:000689210.024
heterocycle metabolic processGO:00464832900.024
regulation of cellular ketone metabolic processGO:001056570.024
neurotransmitter secretionGO:000726920.024
beta amyloid metabolic processGO:005043510.024
cellular response to starvationGO:000926710.024
establishment of protein localizationGO:0045184140.024
cell divisionGO:0051301200.023
Fly
positive regulation of apoptotic signaling pathwayGO:200123510.023
membrane invaginationGO:001032410.023
cellular response to organic substanceGO:00713101050.023
motor neuron axon guidanceGO:0008045230.023
cytokinesisGO:000091030.023
Fly
central nervous system neuron differentiationGO:0021953740.023
primary neural tube formationGO:001402010.023
fin morphogenesisGO:0033334530.023
organelle organizationGO:00069962270.023
chromosome localizationGO:005000020.022
cellular monovalent inorganic cation homeostasisGO:003000420.022
regulation of cellular component organizationGO:0051128860.022
phosphorus metabolic processGO:00067931090.022
regulation of cellular protein metabolic processGO:0032268520.022
cell cycleGO:0007049930.022
Fly
organic substance catabolic processGO:1901575280.022
neural tube developmentGO:0021915620.022
protein modification processGO:00362111000.022
metencephalon developmentGO:0022037270.022
actomyosin structure organizationGO:0031032530.022
biosynthetic processGO:00090582940.022
mitotic cell cycleGO:0000278640.022
wnt signaling pathwayGO:0016055800.021
regulation of cellular amino acid metabolic processGO:000652100.021
regulation of stem cell proliferationGO:007209120.021
cation transmembrane transportGO:0098655650.021
regulation of protein targetingGO:190353320.021
establishment of vesicle localizationGO:0051650240.021
cellular amine metabolic processGO:004410620.021
response to unfolded proteinGO:000698620.021
localization within membraneGO:005166810.021
multicellular organism reproductionGO:0032504350.021
organic cyclic compound biosynthetic processGO:19013622230.021
ion homeostasisGO:0050801410.020
regulation of reproductive processGO:200024140.020
response to organic substanceGO:00100331530.020
cellular response to stressGO:0033554620.020
ribonucleoside monophosphate catabolic processGO:000915840.019
positive regulation of protein complex assemblyGO:003133420.019
homeostatic processGO:00425921420.019
reproductive processGO:0022414400.019
proteasomal protein catabolic processGO:001049820.019
cellular process involved in reproduction in multicellular organismGO:0022412280.019
specification of symmetryGO:00097992040.019
neuron projection guidanceGO:0097485860.019
multi organism processGO:00517041340.019
neurotransmitter transportGO:000683620.019
gtp catabolic processGO:000618420.019
regulation of cell developmentGO:00602841000.019
stem cell proliferationGO:007208940.019
single organism nuclear importGO:190259330.019
purine containing compound metabolic processGO:0072521290.019
embryonic skeletal system morphogenesisGO:0048704930.019
macromolecule biosynthetic processGO:00090592270.019
golgi organizationGO:000703010.019
transcription from rna polymerase ii promoterGO:0006366800.018
growthGO:00400071740.018
digestive system developmentGO:00551232890.018
positive regulation of cellular amine metabolic processGO:003324000.018
oocyte anterior posterior axis specificationGO:000731440.018
single fertilizationGO:000733830.018
innate immune responseGO:0045087130.018
embryonic cranial skeleton morphogenesisGO:0048701900.018
developmental maturationGO:0021700340.018
carboxylic acid metabolic processGO:0019752220.018
stem cell divisionGO:001714510.018
positive regulation of chromatin modificationGO:190331010.018
vacuolar transportGO:000703420.018
regulation of cellular metabolic processGO:00313233200.018
cytoskeleton organizationGO:0007010960.018
embryonic heart tube morphogenesisGO:00031431080.018
positive regulation of immune system processGO:0002684170.018
germ cell developmentGO:0007281220.017
atp catabolic processGO:000620040.017
regulation of synaptic plasticityGO:004816710.017
cellular transition metal ion homeostasisGO:004691630.017
cartilage developmentGO:0051216960.017
developmental growthGO:00485891660.017
organophosphate metabolic processGO:0019637370.017
cell matrix adhesionGO:000716040.017
muscle cell differentiationGO:00426921390.017
cell adhesionGO:0007155400.017
negative regulation of intracellular transportGO:003238730.017
embryonic pattern specificationGO:0009880440.017
muscle organ developmentGO:00075171010.017
cellular nitrogen compound biosynthetic processGO:00442712180.017
tissue remodelingGO:004877140.016
axon guidanceGO:0007411860.016
digestive tract developmentGO:00485652650.016
nuclear transportGO:005116940.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
cellular aromatic compound metabolic processGO:00067252950.016
hepatocyte proliferationGO:007257420.016
gtp metabolic processGO:004603940.016
positive regulation of nucleoside metabolic processGO:004597910.016
response to topologically incorrect proteinGO:003596620.016
detection of abiotic stimulusGO:0009582240.016
diencephalon developmentGO:0021536580.016
intracellular signal transductionGO:0035556850.016
multicellular organismal reproductive processGO:0048609350.016
negative regulation of protein kinase activityGO:000646940.015
negative regulation of cell communicationGO:0010648960.015
negative regulation of catabolic processGO:000989530.015
regulation of cell differentiationGO:00455951420.015
angiogenesisGO:00015251580.015
positive regulation of signal transductionGO:0009967560.015
circulatory system processGO:0003013870.015
interspecies interaction between organismsGO:004441940.015
negative regulation of protein phosphorylationGO:000193340.015
hepaticobiliary system developmentGO:0061008980.015
gastrulationGO:00073692080.015
positive regulation of macromolecule metabolic processGO:0010604930.015
regulation of bindingGO:005109830.015
regulation of defense responseGO:0031347140.015
cellular protein metabolic processGO:00442671290.015
cell substrate adhesionGO:003158940.015
stem cell differentiationGO:00488631170.015
cellular ion homeostasisGO:0006873170.015
multicellular organismal metabolic processGO:004423620.015
response to endogenous stimulusGO:0009719830.015
oogenesisGO:0048477140.015
regulation of cell sizeGO:0008361290.015
pigmentationGO:0043473850.015
regulation of epithelial cell proliferationGO:005067830.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
sensory system developmentGO:0048880760.014
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.014
epidermis morphogenesisGO:004873040.014
regulation of transcription from rna polymerase ii promoterGO:00063571140.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
heart developmentGO:00075073130.014
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.014
chemotaxisGO:00069351040.014
regulation of protein bindingGO:004339330.014
organic cyclic compound metabolic processGO:19013603010.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
posttranscriptional regulation of gene expressionGO:0010608140.014
cytoplasm organizationGO:000702840.014
cellular ketone metabolic processGO:0042180110.014
macromolecule modificationGO:00434121110.014
regulation of mitotic cell cycle embryonicGO:000979420.014
regulation of neurogenesisGO:0050767870.013
regulation of nucleotide catabolic processGO:003081120.013
regulation of multicellular organism growthGO:004001440.013
regulation of rna metabolic processGO:00512522240.013
erk1 and erk2 cascadeGO:007037140.013
cellular response to growth factor stimulusGO:0071363390.013
regulation of receptor mediated endocytosisGO:004825940.013
regulation of synapse assemblyGO:005196330.013
transition metal ion transportGO:000004160.013
negative regulation of ras protein signal transductionGO:004658010.013
macroautophagyGO:001623610.013
determination of bilateral symmetryGO:00098552040.013
mitotic cell cycle processGO:1903047480.013
regulation of nitrogen compound metabolic processGO:00511712510.013
spermatid developmentGO:000728620.013
rna biosynthetic processGO:00327741810.013
regulation of macromolecule biosynthetic processGO:00105562250.013
morphogenesis of an epitheliumGO:00020093330.013
guanosine containing compound metabolic processGO:190106840.013
specification of axis polarityGO:006500140.013
maternal determination of anterior posterior axis embryoGO:000835840.013
tube closureGO:006060610.013
negative regulation of programmed cell deathGO:0043069580.012
protein complex assemblyGO:0006461300.012
transcription dna templatedGO:00063511810.012
centrosome cycleGO:000709810.012
ribonucleotide metabolic processGO:0009259270.012
purine ribonucleotide metabolic processGO:0009150270.012
regionalizationGO:00030022740.012
negative regulation of signal transductionGO:0009968940.012
regulation of cellular response to growth factor stimulusGO:0090287350.012
single organism membrane organizationGO:0044802200.012
embryonic heart tube developmentGO:00350501330.012
regulation of collateral sprouting in absence of injuryGO:004869640.012
zinc ion transportGO:000682920.012
regulation of calcium ion transportGO:005192420.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
muscle structure developmentGO:00610611960.012
blood vessel developmentGO:00015682460.012
cellular homeostasisGO:0019725260.012
regulation of gene expressionGO:00104682650.012
nucleoside monophosphate catabolic processGO:000912540.012
cellular response to unfolded proteinGO:003462020.012
protein localization to plasma membraneGO:007265910.012
meiotic chromosome segregationGO:004513230.012
system processGO:00030081850.012
Human
somitogenesisGO:0001756870.012
lateral inhibitionGO:004633110.012
regulation of retinoic acid biosynthetic processGO:190005260.012
organophosphate biosynthetic processGO:0090407230.011
female gamete generationGO:0007292140.011
negative regulation of kinase activityGO:003367340.011
production of molecular mediator of immune responseGO:000244020.011
notch signaling pathwayGO:0007219350.011
response to steroid hormoneGO:0048545350.011
myofibril assemblyGO:0030239480.011
endoplasmic reticulum unfolded protein responseGO:003096820.011
pronuclear migrationGO:003504610.011
skeletal system morphogenesisGO:00487051020.011
organelle fusionGO:004828430.011
cellular response to estrogen stimulusGO:0071391240.011
regulation of kinase activityGO:0043549150.011
activation of mapk activityGO:000018730.011
establishment of rna localizationGO:005123630.011
negative regulation of protein import into nucleusGO:004230820.011
asymmetric protein localizationGO:000810560.011
cilium morphogenesisGO:0060271850.011
positive regulation of cellular metabolic processGO:0031325940.011
germ line stem cell divisionGO:004207810.011
spindle assemblyGO:005122520.011
response to inorganic substanceGO:0010035380.011
chemical homeostasisGO:0048878490.011
viral processGO:001603210.011
detection of external stimulusGO:0009581240.011
p38mapk cascadeGO:003806610.011
regulation of purine nucleotide catabolic processGO:003312120.011
positive regulation of epithelial cell migrationGO:001063420.011
forebrain cell migrationGO:002188510.011
cellular response to endogenous stimulusGO:0071495680.011

copa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.270
nervous system diseaseDOID:86300.063
musculoskeletal system diseaseDOID:1700.030
muscle tissue diseaseDOID:6600.030
myopathyDOID:42300.030
muscular diseaseDOID:008000000.030
disease of cellular proliferationDOID:1456600.024
cancerDOID:16200.024
endocrine gland cancerDOID:17000.021
organ system cancerDOID:005068600.021
neurodegenerative diseaseDOID:128900.011
central nervous system diseaseDOID:33100.011