Danio rerio

33 known processes

c1qa

complement component 1, q subcomponent, A chain

(Aliases: MGC109903,zgc:109903)

c1qa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.081
larval developmentGO:000216420.075
signal transductionGO:00071654550.074
activation of immune responseGO:000225390.073
immune system processGO:00023762410.067
immune effector processGO:0002252230.062
regulation of cytokine productionGO:000181730.060
regulation of establishment of protein localizationGO:007020140.059
positive regulation of lymphocyte mediated immunityGO:000270810.053
multicellular organism growthGO:003526440.052
positive regulation of transportGO:005105020.051
regulation of protein transportGO:005122330.050
cell surface receptor signaling pathwayGO:00071663250.050
response to external stimulusGO:00096052640.049
Zebrafish
defense responseGO:0006952470.049
Zebrafish
b cell activationGO:004211320.048
positive regulation of cell activationGO:005086710.048
leukocyte proliferationGO:007066110.047
cellular response to external stimulusGO:007149620.046
regulation of multicellular organism growthGO:004001440.045
complement activationGO:000695630.045
regulation of response to stimulusGO:00485832690.045
multicellular organismal metabolic processGO:004423620.044
response to chemicalGO:00422213200.044
regulation of production of molecular mediator of immune responseGO:000270010.043
positive regulation of cytokine productionGO:000181920.042
response to drugGO:004249330.040
response to bacteriumGO:0009617580.040
Zebrafish
regulation of reactive oxygen species metabolic processGO:200037720.039
protein secretionGO:000930610.038
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.038
protein activation cascadeGO:007237660.037
positive regulation of interferon beta productionGO:003272810.037
mononuclear cell proliferationGO:003294310.037
positive regulation of immune effector processGO:000269930.036
embryonic organ developmentGO:00485683810.036
blood vessel developmentGO:00015682460.035
Zebrafish
single organism nuclear importGO:190259330.034
response to carbohydrateGO:000974330.034
nucleocytoplasmic transportGO:000691340.034
regulation of gene expressionGO:00104682650.034
Zebrafish
response to stressGO:00069502630.034
Zebrafish
humoral immune response mediated by circulating immunoglobulinGO:000245530.034
cellular response to lipopolysaccharideGO:007122230.033
b cell mediated immunityGO:001972430.033
autophagyGO:000691440.033
negative regulation of cytokine productionGO:000181810.033
establishment of protein localization to organelleGO:007259440.032
regulation of inflammatory responseGO:005072720.032
cellular response to molecule of bacterial originGO:007121930.031
reactive nitrogen species metabolic processGO:200105700.031
regulation of multicellular organismal processGO:00512392770.031
Human
toll like receptor signaling pathwayGO:000222440.031
sensory perception of chemical stimulusGO:000760630.031
generation of neuronsGO:00486993850.030
oxoacid metabolic processGO:0043436310.030
protein import into nucleusGO:000660630.030
immunoglobulin mediated immune responseGO:001606430.029
lymphocyte proliferationGO:004665110.029
response to external biotic stimulusGO:0043207970.029
Zebrafish
production of molecular mediator of immune responseGO:000244020.029
response to nutrientGO:000758430.028
regulation of cell activationGO:005086510.028
maintenance of locationGO:005123540.028
response to organic substanceGO:00100331530.027
positive regulation of biological processGO:00485182530.027
amine metabolic processGO:000930820.027
regulation of cellular amine metabolic processGO:003323800.027
protein targeting to nucleusGO:004474430.027
lipid storageGO:001991510.026
regulation of primary metabolic processGO:00800903110.026
Zebrafish
single organism metabolic processGO:00447102170.026
response to monosaccharideGO:003428430.026
cellular protein catabolic processGO:004425740.026
positive regulation of secretionGO:005104710.025
cellular response to chemical stimulusGO:00708871570.025
nuclear importGO:005117030.025
negative regulation of biological processGO:00485193040.025
Human Zebrafish
establishment of localizationGO:00512342440.025
nuclear transportGO:005116940.025
tube morphogenesisGO:00352393490.025
reactive oxygen species biosynthetic processGO:190340910.025
cellular response to nutrient levelsGO:003166920.025
regulation of metabolic processGO:00192223590.025
Zebrafish
regulation of cellular biosynthetic processGO:00313262450.025
response to hexoseGO:000974630.025
protein importGO:001703830.025
cellular amine metabolic processGO:004410620.024
positive regulation of dna metabolic processGO:005105410.024
positive regulation of secretion by cellGO:190353210.024
regulation of metal ion transportGO:001095940.024
transportGO:00068102200.024
protein localization to plasma membraneGO:007265910.024
stem cell proliferationGO:007208940.024
cell motilityGO:00488702440.024
g protein coupled receptor signaling pathwayGO:0007186740.024
cellular response to starvationGO:000926710.024
regulation of signal transductionGO:00099662250.023
gastrulationGO:00073692080.023
regulation of protein ubiquitinationGO:003139630.023
protein localization to nucleusGO:003450430.023
regulation of autophagyGO:001050630.023
pericardium developmentGO:006003910.023
response to glucocorticoidGO:005138410.023
cellular response to extracellular stimulusGO:003166820.022
angiogenesisGO:00015251580.022
regulation of cellular amino acid metabolic processGO:000652100.022
response to vitaminGO:003327330.022
regulation of bindingGO:005109830.022
response to corticosteroidGO:003196010.022
gtp metabolic processGO:004603940.022
response to biotic stimulusGO:0009607970.022
Zebrafish
blood vessel morphogenesisGO:00485142160.022
Zebrafish
regulation of phGO:000688530.022
positive regulation of leukocyte mediated immunityGO:000270510.022
single organism transportGO:00447652060.022
peptidyl lysine acetylationGO:001839420.022
phagocytosisGO:000690930.021
cellular biosynthetic processGO:00442492860.021
neuron neuron synaptic transmissionGO:000727010.021
organic acid metabolic processGO:0006082310.021
nitric oxide biosynthetic processGO:000680920.021
regulation of cellular metabolic processGO:00313233200.021
Zebrafish
cellular ketone metabolic processGO:0042180110.021
response to ketoneGO:190165410.021
multicellular organismal macromolecule metabolic processGO:004425920.021
regulation of multicellular organismal developmentGO:20000262230.021
Human
symbiosis encompassing mutualism through parasitismGO:004440340.021
ameboidal type cell migrationGO:00016671430.021
regulation of protein complex assemblyGO:004325430.021
ion transmembrane transportGO:0034220910.021
regulation of tube sizeGO:003515020.020
regulation of i kappab kinase nf kappab signalingGO:004312240.020
digestive tract morphogenesisGO:00485462310.020
negative regulation of protein phosphorylationGO:000193340.020
heterocycle metabolic processGO:00464832900.020
peptide transportGO:001583310.020
regulation of cell communicationGO:00106462320.020
transmembrane transportGO:00550851200.020
heart developmentGO:00075073130.020
regulation of biological qualityGO:00650082630.020
regulation of biosynthetic processGO:00098892500.020
heterocycle biosynthetic processGO:00181302150.020
regulation of cellular ketone metabolic processGO:001056570.020
brain developmentGO:00074202930.020
positive regulation of cellular amino acid metabolic processGO:004576400.020
cellular macromolecule metabolic processGO:00442603910.020
Zebrafish
protein acetylationGO:000647320.020
cellular response to organic substanceGO:00713101050.020
vasculature developmentGO:00019442780.020
Zebrafish
response to glucoseGO:000974930.019
carboxylic acid metabolic processGO:0019752220.019
digestive tract developmentGO:00485652650.019
regulation of protein import into nucleusGO:004230620.019
regulation of signalingGO:00230512350.019
regulation of cell shapeGO:000836010.019
gene expressionGO:00104672520.019
Zebrafish
biosynthetic processGO:00090582940.019
response to abiotic stimulusGO:00096281220.019
positive regulation of map kinase activityGO:004340630.019
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
organic cyclic compound biosynthetic processGO:19013622230.019
positive regulation of cellular amine metabolic processGO:003324000.019
synaptic transmission cholinergicGO:000727140.019
regulation of blood vessel sizeGO:005088020.019
cellular response to biotic stimulusGO:007121630.018
stem cell maintenanceGO:001982740.018
positive regulation of inflammatory responseGO:005072910.018
regulation of muscle contractionGO:000693730.018
nitrogen compound metabolic processGO:00068073190.018
immune responseGO:0006955280.018
intracellular signal transductionGO:0035556850.018
negative regulation of cellular catabolic processGO:003133030.018
negative regulation of catabolic processGO:000989530.018
type i interferon productionGO:003260620.018
protein metabolic processGO:00195381830.018
immune system developmentGO:00025201910.018
Human
regulation of glucose transportGO:001082710.018
cytokinesisGO:000091030.018
positive regulation of cell cycleGO:004578730.018
negative regulation of protein transportGO:005122430.018
cell substrate adhesionGO:003158940.018
i kappab kinase nf kappab signalingGO:000724940.018
cognitionGO:005089010.018
homeostatic processGO:00425921420.018
modification dependent macromolecule catabolic processGO:004363230.018
protein heterooligomerizationGO:005129110.018
regulation of cellular phGO:003064110.017
regulation of protein localization to nucleusGO:190018020.017
regulation of macromolecule metabolic processGO:00602553170.017
Zebrafish
proteolysis involved in cellular protein catabolic processGO:005160330.017
collagen metabolic processGO:003296320.017
regulation of response to nutrient levelsGO:003210710.017
neuron differentiationGO:00301823530.017
regulation of nitrogen compound metabolic processGO:00511712510.017
specification of symmetryGO:00097992040.017
inositol lipid mediated signalingGO:004801720.017
inorganic cation transmembrane transportGO:0098662500.017
multi organism processGO:00517041340.017
Zebrafish
digestive system developmentGO:00551232890.017
negative regulation of defense responseGO:003134820.017
response to woundingGO:00096111160.017
peptide metabolic processGO:000651810.017
positive regulation of catabolic processGO:000989640.017
glucose homeostasisGO:004259310.017
determination of bilateral symmetryGO:00098552040.017
defense response to other organismGO:0098542330.017
Zebrafish
embryo development ending in birth or egg hatchingGO:00097922710.017
cellular component movementGO:00069283350.017
adaptive immune responseGO:000225050.017
neuron developmentGO:00486662620.017
regulation of intracellular protein transportGO:003315730.017
cellular nitrogen compound metabolic processGO:00346412900.017
pericardium morphogenesisGO:000334410.017
regulation of response to cytokine stimulusGO:006075930.017
regulation of developmental processGO:00507932470.017
Human
stem cell divisionGO:001714510.017
establishment of protein localization to plasma membraneGO:009000210.017
morphogenesis of an epitheliumGO:00020093330.016
regulation of protein catabolic processGO:004217610.016
locomotionGO:00400113130.016
cellular amino acid metabolic processGO:000652070.016
cellular component morphogenesisGO:00329893360.016
hemopoiesisGO:00300971830.016
Human
glucose importGO:004632320.016
regulation of leukocyte mediated immunityGO:000270310.016
central nervous system developmentGO:00074173870.016
gtp catabolic processGO:000618420.016
ion transportGO:00068111140.016
guanosine containing compound catabolic processGO:190106920.016
tissue remodelingGO:004877140.016
regulation of cytoplasmic transportGO:190364940.016
immunoglobulin productionGO:000237710.016
sprouting angiogenesisGO:0002040530.016
regulation of organ growthGO:004662030.016
rna metabolic processGO:00160702190.016
cation transportGO:0006812810.016
ubiquitin dependent protein catabolic processGO:000651130.016
leukocyte mediated cytotoxicityGO:000190910.016
internal protein amino acid acetylationGO:000647520.016
nucleic acid metabolic processGO:00903042440.016
single organism localizationGO:19025782250.016
response to other organismGO:0051707970.015
Zebrafish
modification dependent protein catabolic processGO:001994130.015
internal peptidyl lysine acetylationGO:001839320.015
regulation of nucleocytoplasmic transportGO:004682220.015
nitric oxide metabolic processGO:004620920.015
regulation of protein targetingGO:190353320.015
inner ear developmentGO:00488391260.015
regulation of innate immune responseGO:0045088110.015
regulation of immune system processGO:0002682340.015
regulation of rho protein signal transductionGO:003502320.015
somatic muscle developmentGO:000752540.015
positive regulation of myeloid cell differentiationGO:004563920.015
cation transmembrane transportGO:0098655650.015
guanosine containing compound metabolic processGO:190106840.015
organic cyclic compound metabolic processGO:19013603010.015
negative regulation of cellular processGO:00485232830.015
Human Zebrafish
cellular amide metabolic processGO:004360340.015
g1 s transition of mitotic cell cycleGO:000008210.015
nucleobase containing compound metabolic processGO:00061392740.015
activation of mapk activityGO:000018730.015
embryonic organ morphogenesisGO:00485622740.015
small molecule metabolic processGO:0044281770.014
organelle organizationGO:00069962270.014
cellular carbohydrate metabolic processGO:004426240.014
regulation of response to biotic stimulusGO:000283120.014
cell migrationGO:00164772370.014
phosphatidylinositol mediated signalingGO:004801520.014
positive regulation of i kappab kinase nf kappab signalingGO:004312330.014
organonitrogen compound metabolic processGO:1901564740.014
developmental growthGO:00485891660.014
carbohydrate homeostasisGO:003350010.014
positive regulation of cellular processGO:00485222010.014
positive regulation of cellular component biogenesisGO:004408930.014
positive regulation of cell adhesionGO:004578510.014
rna biosynthetic processGO:00327741810.014
positive regulation of jnk cascadeGO:004633030.014
deathGO:00162651210.014
Zebrafish
positive regulation of cell killingGO:003134320.014
interspecies interaction between organismsGO:004441940.014
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.014
macroautophagyGO:001623610.014
organic substance biosynthetic processGO:19015762890.014
reactive oxygen species metabolic processGO:007259360.014
determination of heart left right asymmetryGO:00613711170.014
cell migration involved in gastrulationGO:0042074790.013
regulation of photoreceptor cell differentiationGO:004653220.013
fatty acid transportGO:001590810.013
synaptic growth at neuromuscular junctionGO:005112420.013
negative regulation of secretion by cellGO:190353120.013
positive regulation of immune responseGO:0050778110.013
regulation of synaptic plasticityGO:004816710.013
regulation of blood pressureGO:000821710.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
Human
regulation of defense responseGO:0031347140.013
protein acylationGO:004354330.013
phosphatidylinositol 3 kinase signalingGO:001406520.013
meiotic cell cycle processGO:190304630.013
localization of cellGO:00516742440.013
positive regulation of cellular catabolic processGO:003133130.013
regulation of calcium ion transportGO:005192420.013
positive regulation of stress activated mapk cascadeGO:003287430.013
cell cycle g1 s phase transitionGO:004484310.013
germ line stem cell divisionGO:004207810.013
sensory perception of painGO:001923310.013
ear developmentGO:00435831270.013
regulation of response to extracellular stimulusGO:003210410.013
positive regulation of translationGO:004572710.013
regulation of wound healingGO:006104120.013
superoxide metabolic processGO:000680120.013
female sex differentiationGO:004666040.013
single organism membrane fusionGO:004480120.013
chordate embryonic developmentGO:00430092710.013
mitochondrion organizationGO:000700540.013
regulation of dna replicationGO:000627530.013
cellular extravasationGO:004512310.013
regulation of skeletal muscle tissue developmentGO:004864140.013
cellular response to radiationGO:007147840.013
regulation of reproductive processGO:200024140.013
germ line stem cell maintenanceGO:003071820.013
regulation of nucleoside metabolic processGO:000911820.013
negative regulation of autophagyGO:001050710.013
defense response to bacteriumGO:0042742220.012
Zebrafish
regulation of nucleotide catabolic processGO:003081120.012
cellular component biogenesisGO:00440851780.012
regulation of cellular component movementGO:0051270550.012
positive regulation of leukocyte mediated cytotoxicityGO:000191210.012
proteasomal protein catabolic processGO:001049820.012
regulation of purine nucleotide catabolic processGO:003312120.012
growthGO:00400071740.012
protein polyubiquitinationGO:000020940.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
cellular aromatic compound metabolic processGO:00067252950.012
cellular nitrogen compound biosynthetic processGO:00442712180.012
regulation of cellular protein catabolic processGO:190336210.012
regulation of dendrite developmentGO:005077330.012
long chain fatty acid metabolic processGO:000167610.012
regulation of circadian sleep wake cycle sleepGO:004518710.012
antimicrobial humoral responseGO:001973020.012
positive regulation of immune system processGO:0002684170.012
determination of left right symmetryGO:00073681790.012
regulation of locomotionGO:0040012550.012
leukocyte mediated immunityGO:000244360.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
organelle assemblyGO:00709251100.012
phagocytosis engulfmentGO:000691110.012
transcription dna templatedGO:00063511810.012
fatty acid biosynthetic processGO:000663340.012
negative regulation of apoptotic processGO:0043066550.012
Zebrafish
regulation of programmed cell deathGO:00430671010.012
Zebrafish
regulation of cytokine biosynthetic processGO:004203510.012
dna templated transcription elongationGO:000635430.012
cytoskeleton dependent cytokinesisGO:006164030.012
cell projection organizationGO:00300302840.012
cellular monovalent inorganic cation homeostasisGO:003000420.012
establishment of endothelial barrierGO:006102830.012
regulation of cell substrate adhesionGO:001081010.012
organism emergence from protective structureGO:007168440.012
er nucleus signaling pathwayGO:000698420.012
negative regulation of response to stimulusGO:00485851040.012
regulation of stem cell proliferationGO:007209120.012
post embryonic organ developmentGO:004856940.012
compound eye developmentGO:004874920.011
embryonic hemopoiesisGO:0035162530.011
epithelial tube morphogenesisGO:00605621480.011
regulation of cell deathGO:00109411030.011
Zebrafish
cell deathGO:00082191210.011
Zebrafish
protein stabilizationGO:005082120.011
atp catabolic processGO:000620040.011
transcription from rna polymerase ii promoterGO:0006366800.011
sensory organ morphogenesisGO:00905962000.011
negative regulation of kinase activityGO:003367340.011
female gonad developmentGO:000858540.011
positive regulation of gliogenesisGO:001401520.011
regulation of cardiac muscle contractionGO:005511720.011
positive regulation of stem cell proliferationGO:200064810.011
cell morphogenesisGO:00009022890.011
system processGO:00030081850.011
regulation of nucleobase containing compound metabolic processGO:00192192500.011
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.011
regenerationGO:0031099910.011
response to virusGO:0009615210.011
response to topologically incorrect proteinGO:003596620.011
regulation of protein bindingGO:004339330.011
axonogenesisGO:00074091520.011
somatic cell dna recombinationGO:001644410.011
regulation of immune responseGO:0050776140.011
actin mediated cell contractionGO:007025210.011
positive regulation of response to stimulusGO:0048584800.011
regulation of striated muscle contractionGO:000694220.011
bicarbonate transportGO:001570140.011
regulation of cytokine mediated signaling pathwayGO:000195930.011
cell part morphogenesisGO:00329902460.011
negative regulation of ras protein signal transductionGO:004658010.011
macromolecule modificationGO:00434121110.011
negative regulation of small gtpase mediated signal transductionGO:005105810.011
head developmentGO:00603223030.011
regulation of localizationGO:00328791040.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
single fertilizationGO:000733830.011
nucleobase containing compound biosynthetic processGO:00346542050.011
regulation of dna recombinationGO:000001820.011
cellular component disassemblyGO:002241110.011
extrinsic apoptotic signaling pathwayGO:009719130.011
regulation of natural killer cell mediated immunityGO:000271510.011
small gtpase mediated signal transductionGO:000726480.011
regulation of rna biosynthetic processGO:20011412130.011
interferon beta productionGO:003260810.010
negative regulation of secretionGO:005104820.010
regulation of jak stat cascadeGO:004642530.010
energy reserve metabolic processGO:000611220.010
response to uvGO:000941130.010
negative regulation of multi organism processGO:004390130.010
regulation of intracellular phGO:005145310.010
regulation of gtpase activityGO:004308720.010
organic substance transportGO:0071702580.010
regulation of rna metabolic processGO:00512522240.010
secondary metabolic processGO:001974830.010
erk1 and erk2 cascadeGO:007037140.010
regulation of tyrosine phosphorylation of stat3 proteinGO:004251610.010
cellular protein modification processGO:00064641000.010
cell killingGO:000190620.010
skeletal system developmentGO:00015011810.010
response to lipidGO:0033993600.010
regulation of cellular carbohydrate metabolic processGO:001067540.010
actin filament based movementGO:003004810.010
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.010
regulation of cellular macromolecule biosynthetic processGO:20001122220.010
organelle fusionGO:004828430.010
toxin transportGO:190199820.010
positive regulation of small gtpase mediated signal transductionGO:005105710.010
peptidyl serine phosphorylationGO:001810510.010
regulation of circadian rhythmGO:004275240.010
gas transportGO:001566930.010
positive regulation of defense responseGO:003134990.010

c1qa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
disease of metabolismDOID:001466700.021
nervous system diseaseDOID:86300.019
eye and adnexa diseaseDOID:149200.017
sensory system diseaseDOID:005015500.017
inherited metabolic disorderDOID:65500.015
eye diseaseDOID:561400.013
musculoskeletal system diseaseDOID:1700.013
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
retinal diseaseDOID:567900.011
organ system cancerDOID:005068600.010