Danio rerio

0 known processes

arhgef1

rho guanine nucleotide exchange factor (GEF) 1

(Aliases: zgc:158261,cb473)

arhgef1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell projection organizationGO:00300302840.211
protein polymerizationGO:005125840.173
larval developmentGO:000216420.148
neuron developmentGO:00486662620.141
blood vessel developmentGO:00015682460.134
response to stressGO:00069502630.123
cortical cytoskeleton organizationGO:003086510.109
neuron differentiationGO:00301823530.107
localization of cellGO:00516742440.103
adherens junction organizationGO:003433240.102
endosomal transportGO:001619720.097
compound eye developmentGO:004874920.091
cell motilityGO:00488702440.085
single organism organelle organizationGO:19025891990.083
hemopoiesisGO:00300971830.083
cortical actin cytoskeleton organizationGO:003086610.082
cellular component movementGO:00069283350.080
regulation of biological qualityGO:00650082630.078
head developmentGO:00603223030.071
immune system developmentGO:00025201910.069
regulation of nitrogen compound metabolic processGO:00511712510.068
lipid storageGO:001991510.065
positive regulation of biological processGO:00485182530.065
eye developmentGO:00016542770.064
response to chemicalGO:00422213200.064
regulation of metabolic processGO:00192223590.062
central nervous system developmentGO:00074173870.061
signal transductionGO:00071654550.061
morphogenesis of an epitheliumGO:00020093330.059
cell migrationGO:00164772370.058
maintenance of locationGO:005123540.058
vasculature developmentGO:00019442780.056
purine nucleoside monophosphate catabolic processGO:000912840.053
agingGO:000756820.053
cellular nitrogen compound metabolic processGO:00346412900.052
phagocytosisGO:000690930.052
multicellular organism growthGO:003526440.051
regulation of macromolecule metabolic processGO:00602553170.048
atp catabolic processGO:000620040.048
cell part morphogenesisGO:00329902460.048
nucleic acid metabolic processGO:00903042440.046
positive regulation of cellular catabolic processGO:003133130.046
cellular protein metabolic processGO:00442671290.044
response to external stimulusGO:00096052640.044
macromolecular complex disassemblyGO:003298410.042
small molecule metabolic processGO:0044281770.042
protein metabolic processGO:00195381830.042
regulation of cellular macromolecule biosynthetic processGO:20001122220.042
cell morphogenesis involved in differentiationGO:00009041950.041
generation of neuronsGO:00486993850.041
brain developmentGO:00074202930.041
cellular component disassemblyGO:002241110.040
nucleobase containing compound metabolic processGO:00061392740.040
cytoskeleton organizationGO:0007010960.040
regulation of intracellular protein transportGO:003315730.040
cellular macromolecule metabolic processGO:00442603910.039
organonitrogen compound metabolic processGO:1901564740.039
carboxylic acid metabolic processGO:0019752220.039
homeostasis of number of cellsGO:0048872620.038
heterocycle metabolic processGO:00464832900.038
gtp catabolic processGO:000618420.037
regulation of synapse assemblyGO:005196330.037
positive regulation of catabolic processGO:000989640.037
adult behaviorGO:003053420.037
purine ribonucleoside monophosphate catabolic processGO:000916940.036
ribonucleoside monophosphate catabolic processGO:000915840.036
protein targeting to nucleusGO:004474430.036
microtubule depolymerizationGO:000701910.036
ribonucleotide metabolic processGO:0009259270.035
nitrogen compound metabolic processGO:00068073190.035
negative regulation of biological processGO:00485193040.035
phosphate containing compound metabolic processGO:00067961080.034
regulation of protein transportGO:005122330.034
gtp metabolic processGO:004603940.034
erythrocyte differentiationGO:0030218540.034
single organism metabolic processGO:00447102170.033
positive regulation of transportGO:005105020.033
guanosine containing compound metabolic processGO:190106840.033
regulation of primary metabolic processGO:00800903110.033
striated muscle tissue developmentGO:00147061100.032
single organism nuclear importGO:190259330.032
regulation of synapse organizationGO:005080730.032
heart developmentGO:00075073130.032
cellular protein modification processGO:00064641000.031
regulation of developmental processGO:00507932470.031
embryo development ending in birth or egg hatchingGO:00097922710.030
macromolecular complex subunit organizationGO:0043933740.030
single organism localizationGO:19025782250.030
macromolecule modificationGO:00434121110.030
regulation of cellular amine metabolic processGO:003323800.030
regulation of anatomical structure morphogenesisGO:00226031300.029
protein acetylationGO:000647320.029
regulation of protein complex disassemblyGO:004324410.029
protein complex disassemblyGO:004324110.029
erk1 and erk2 cascadeGO:007037140.029
regulation of autophagyGO:001050630.029
regulation of multicellular organismal processGO:00512392770.028
regulation of protein complex assemblyGO:004325430.028
negative regulation of protein phosphorylationGO:000193340.028
cellular biosynthetic processGO:00442492860.027
cell projection morphogenesisGO:00488582440.027
regulation of protein polymerizationGO:003227120.027
somatic muscle developmentGO:000752540.027
growthGO:00400071740.027
organophosphate metabolic processGO:0019637370.027
tube morphogenesisGO:00352393490.027
actin cytoskeleton organizationGO:0030036630.027
regulation of erk1 and erk2 cascadeGO:007037240.027
regulation of cytoplasmic transportGO:190364940.027
ribose phosphate metabolic processGO:0019693270.027
regulation of nucleocytoplasmic transportGO:004682220.026
regulation of multicellular organismal developmentGO:20000262230.026
response to uvGO:000941130.026
organic substance biosynthetic processGO:19015762890.026
regulation of purine nucleotide catabolic processGO:003312120.026
regulation of dna templated transcription in response to stressGO:004362000.026
regulation of reproductive processGO:200024140.026
autophagyGO:000691440.026
neuron projection developmentGO:00311751800.026
internal protein amino acid acetylationGO:000647520.025
hematopoietic or lymphoid organ developmentGO:00485341910.025
guanosine containing compound catabolic processGO:190106920.025
nucleotide metabolic processGO:0009117280.025
angiogenesisGO:00015251580.025
erythrocyte homeostasisGO:0034101550.025
neuron projection regenerationGO:0031102160.025
positive regulation of cellular component biogenesisGO:004408930.025
adherens junction assemblyGO:003433310.025
peptidyl serine phosphorylationGO:001810510.025
myoblast fusionGO:0007520100.025
cellular component biogenesisGO:00440851780.025
regulation of protein depolymerizationGO:190187910.024
protein localization to plasma membraneGO:007265910.024
actin polymerization or depolymerizationGO:000815420.024
cellular component assemblyGO:00226071700.024
regulation of biosynthetic processGO:00098892500.024
regulation of establishment of protein localizationGO:007020140.023
cellular response to chemical stimulusGO:00708871570.023
small gtpase mediated signal transductionGO:000726480.023
positive regulation of protein polymerizationGO:003227320.023
cellular protein complex assemblyGO:0043623190.023
cellular macromolecular complex assemblyGO:0034622240.023
regulation of myotube differentiationGO:001083020.023
immune system processGO:00023762410.023
microtubule based processGO:0007017600.023
regulation of nucleoside metabolic processGO:000911820.023
aromatic compound biosynthetic processGO:00194382170.023
carboxylic acid catabolic processGO:004639530.022
amine metabolic processGO:000930820.022
negative regulation of metabolic processGO:0009892860.022
nucleoside monophosphate catabolic processGO:000912540.022
cell morphogenesis involved in neuron differentiationGO:00486671630.022
cell morphogenesisGO:00009022890.022
sensory organ developmentGO:00074233930.022
cellular localizationGO:0051641970.022
vasculogenesisGO:0001570410.022
protein depolymerizationGO:005126110.022
regulation of gtpase activityGO:004308720.022
regulation of natural killer cell mediated immunityGO:000271510.022
septum transversum developmentGO:000334340.022
angioblast cell migration involved in selective angioblast sproutingGO:003547540.021
nuclear transportGO:005116940.021
nucleobase containing small molecule metabolic processGO:0055086320.021
organic acid metabolic processGO:0006082310.021
modification dependent protein catabolic processGO:001994130.021
negative regulation of nitrogen compound metabolic processGO:0051172590.021
regulation of cell motilityGO:2000145460.021
intracellular signal transductionGO:0035556850.021
organic cyclic compound metabolic processGO:19013603010.021
regulation of gtp catabolic processGO:003312420.021
cellular component morphogenesisGO:00329893360.020
neuron neuron synaptic transmissionGO:000727010.020
macromolecule biosynthetic processGO:00090592270.020
regulation of signal transductionGO:00099662250.020
regulation of cell differentiationGO:00455951420.020
cellular response to nutrient levelsGO:003166920.020
protein import into nucleusGO:000660630.020
cell fate commitmentGO:0045165990.020
proteolysis involved in cellular protein catabolic processGO:005160330.020
endothelial cell developmentGO:0001885120.020
protein localization to nucleusGO:003450430.020
positive regulation of gtp catabolic processGO:003312610.020
embryonic heart tube developmentGO:00350501330.020
regulation of cell shapeGO:000836010.020
ras protein signal transductionGO:000726570.020
regulation of nucleobase containing compound metabolic processGO:00192192500.020
myotube differentiationGO:0014902450.020
regulation of cellular amino acid metabolic processGO:000652100.020
blood vessel morphogenesisGO:00485142160.019
regulation of cell activationGO:005086510.019
negative regulation of cellular processGO:00485232830.019
membrane invaginationGO:001032410.019
organelle organizationGO:00069962270.019
regulation of locomotionGO:0040012550.019
oxoacid metabolic processGO:0043436310.019
regulation of cellular metabolic processGO:00313233200.019
protein importGO:001703830.019
establishment of protein localization to organelleGO:007259440.019
regulation of nucleotide catabolic processGO:003081120.018
cellular macromolecule biosynthetic processGO:00346452240.018
cellular response to methanolGO:007140540.018
establishment of localizationGO:00512342440.018
system processGO:00030081850.018
positive regulation of cellular carbohydrate metabolic processGO:001067610.018
sulfur compound biosynthetic processGO:004427290.018
axon regenerationGO:0031103140.018
muscle structure developmentGO:00610611960.018
transportGO:00068102200.018
cell surface receptor signaling pathwayGO:00071663250.018
muscle cell differentiationGO:00426921390.018
cell deathGO:00082191210.018
response to organic substanceGO:00100331530.017
response to amino acidGO:004320020.017
regulation of cell projection assemblyGO:006049140.017
regulation of response to extracellular stimulusGO:003210410.017
regulation of response to stimulusGO:00485832690.017
cellular carbohydrate metabolic processGO:004426240.017
heart morphogenesisGO:00030071560.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
negative regulation of ras protein signal transductionGO:004658010.017
convergent extensionGO:00600261180.017
regulation of cellular component organizationGO:0051128860.017
mitotic cell cycle processGO:1903047480.017
regulation of protein import into nucleusGO:004230620.017
regulation of bindingGO:005109830.017
regulation of inflammatory responseGO:005072720.017
cellular response to oxygen levelsGO:007145310.017
regulation of cytokine productionGO:000181730.016
positive regulation of cellular amine metabolic processGO:003324000.016
positive regulation of gtpase activityGO:004354710.016
protein phosphorylationGO:0006468470.016
cellular amino acid metabolic processGO:000652070.016
nucleocytoplasmic transportGO:000691340.016
protein dephosphorylationGO:000647030.016
multi organism cellular processGO:004476420.016
inositol lipid mediated signalingGO:004801720.016
cellular protein catabolic processGO:004425740.016
pole plasm assemblyGO:000731540.016
neuroblast proliferationGO:000740520.016
proteasomal protein catabolic processGO:001049820.016
epithelial cell morphogenesisGO:000338220.016
cellular protein complex disassemblyGO:004362410.016
transcription dna templatedGO:00063511810.016
positive regulation of cell adhesionGO:004578510.015
stem cell maintenanceGO:001982740.015
response to nutrientGO:000758430.015
regulation of metal ion transportGO:001095940.015
embryonic hemopoiesisGO:0035162530.015
nucleic acid templated transcriptionGO:00976591810.015
cytokinesisGO:000091030.015
establishment of endothelial barrierGO:006102830.015
regulation of intracellular signal transductionGO:1902531570.015
phosphorus metabolic processGO:00067931090.015
nucleoside phosphate metabolic processGO:0006753280.015
cardiac muscle tissue morphogenesisGO:005500870.015
protein acylationGO:004354330.015
phagocytosis engulfmentGO:000691110.015
locomotionGO:00400113130.015
cellular aromatic compound metabolic processGO:00067252950.015
receptor recyclingGO:000188140.015
establishment of protein localization to plasma membraneGO:009000210.015
positive regulation of protein complex assemblyGO:003133420.015
epithelial tube morphogenesisGO:00605621480.015
cell substrate junction assemblyGO:000704420.015
regulation of dendrite developmentGO:005077330.015
digestive tract developmentGO:00485652650.014
response to drugGO:004249330.014
regulation of microtubule cytoskeleton organizationGO:007050730.014
rna biosynthetic processGO:00327741810.014
positive regulation of erk1 and erk2 cascadeGO:007037420.014
g protein coupled receptor signaling pathwayGO:0007186740.014
intracellular receptor signaling pathwayGO:0030522300.014
proepicardium developmentGO:000334240.014
regulation of cellular biosynthetic processGO:00313262450.014
myeloid cell differentiationGO:0030099860.014
negative regulation of macromolecule metabolic processGO:0010605760.014
positive regulation of secretionGO:005104710.014
meiotic nuclear divisionGO:000712640.014
homeostatic processGO:00425921420.014
regulation of localizationGO:00328791040.014
ubiquitin dependent protein catabolic processGO:000651130.014
rna localizationGO:000640340.014
positive regulation of metabolic processGO:00098931080.014
cellular response to stressGO:0033554620.014
nucleobase containing compound biosynthetic processGO:00346542050.014
positive regulation of cell cycleGO:004578730.014
peptidyl threonine phosphorylationGO:001810710.014
regulation of protein catabolic processGO:004217610.014
syncytium formation by plasma membrane fusionGO:0000768120.013
organelle localizationGO:0051640490.013
positive regulation of nucleotide catabolic processGO:003081310.013
cellular response to decreased oxygen levelsGO:003629410.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
establishment of mitotic spindle localizationGO:0040001120.013
peptidyl serine modificationGO:001820920.013
natural killer cell mediated immunityGO:000222810.013
ventricular cardiac muscle tissue developmentGO:000322930.013
single organism transportGO:00447652060.013
negative regulation of reproductive processGO:200024230.013
negative regulation of dna metabolic processGO:005105340.013
single organism cell adhesionGO:0098602290.013
cellular ketone metabolic processGO:0042180110.013
cellular nitrogen compound biosynthetic processGO:00442712180.013
regulation of transcription dna templatedGO:00063552130.013
modification dependent macromolecule catabolic processGO:004363230.013
cell substrate adhesionGO:003158940.013
protein complex assemblyGO:0006461300.013
regulation of macromolecule biosynthetic processGO:00105562250.013
syncytium formationGO:0006949120.013
synaptic transmission cholinergicGO:000727140.013
regulation of oligodendrocyte differentiationGO:004871310.013
cellular response to extracellular stimulusGO:003166820.013
circulatory system processGO:0003013870.012
neuron projection morphogenesisGO:00488121610.012
response to woundingGO:00096111160.012
regulation of sequestering of calcium ionGO:005128240.012
cell cycleGO:0007049930.012
protein localizationGO:0008104400.012
response to endogenous stimulusGO:0009719830.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
microtubule polymerizationGO:004678520.012
mitochondrion organizationGO:000700540.012
peptidyl lysine acetylationGO:001839420.012
peptidyl threonine modificationGO:001821010.012
regulation of purine nucleotide metabolic processGO:1900542170.012
actin filament based processGO:0030029640.012
digestive system developmentGO:00551232890.012
regulation of receptor mediated endocytosisGO:004825940.012
purine ribonucleotide metabolic processGO:0009150270.012
muscle organ developmentGO:00075171010.012
myeloid cell homeostasisGO:0002262560.012
positive regulation of nucleoside metabolic processGO:004597910.012
purine nucleotide metabolic processGO:0006163270.012
nuclear exportGO:005116810.012
regulation of stem cell proliferationGO:007209120.012
negative regulation of muscle cell differentiationGO:005114810.012
response to corticosteroidGO:003196010.012
locomotor rhythmGO:004547530.012
neurotransmitter transportGO:000683620.012
protein modification processGO:00362111000.012
central nervous system neuron axonogenesisGO:0021955180.012
regulation of signalingGO:00230512350.012
axon developmentGO:00615641660.012
synaptic growth at neuromuscular junctionGO:005112420.012
establishment of synaptic vesicle localizationGO:009748010.012
biological adhesionGO:0022610400.011
negative regulation of chemotaxisGO:005092240.011
regulation of carbohydrate metabolic processGO:000610940.011
rho protein signal transductionGO:000726650.011
striated muscle cell differentiationGO:00511461290.011
calcium mediated signalingGO:001972220.011
cellular response to external stimulusGO:007149620.011
cellular catabolic processGO:0044248270.011
calcium ion dependent exocytosisGO:001715610.011
muscle cell developmentGO:00550011150.011
cellular response to hypoxiaGO:007145610.011
cellular amine metabolic processGO:004410620.011
long chain fatty acid metabolic processGO:000167610.011
microtubule cytoskeleton organizationGO:0000226330.011
regulation of programmed cell deathGO:00430671010.011
morphogenesis of an epithelial sheetGO:0002011490.011
regulation of microtubule polymerization or depolymerizationGO:003111030.011
regulation of cell projection organizationGO:0031344440.011
negative regulation of defense responseGO:003134820.011
developmental growthGO:00485891660.011
internal peptidyl lysine acetylationGO:001839320.011
regulation of multicellular organism growthGO:004001440.011
positive regulation of translationGO:004572710.011
regulation of protein targetingGO:190353320.011
regulation of cardiac muscle tissue developmentGO:005502410.011
regulation of skeletal muscle fiber developmentGO:004874220.011
post embryonic organ developmentGO:004856940.010
regulation of cell communicationGO:00106462320.010
maternal determination of anterior posterior axis embryoGO:000835840.010
phagosome maturationGO:009038210.010
b cell activationGO:004211320.010
primary neural tube formationGO:001402010.010
stem cell divisionGO:001714510.010
carbohydrate homeostasisGO:003350010.010
cognitionGO:005089010.010
g1 s transition of mitotic cell cycleGO:000008210.010
response to organic cyclic compoundGO:0014070510.010
ameboidal type cell migrationGO:00016671430.010
cellular response to radiationGO:007147840.010
axon cargo transportGO:000808820.010
negative regulation of cellular catabolic processGO:003133030.010
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.010
response to alkaloidGO:004327920.010
cellular macromolecule localizationGO:0070727210.010
regulation of tube sizeGO:003515020.010
regulation of phosphorus metabolic processGO:0051174430.010
response to inorganic substanceGO:0010035380.010
negative regulation of multi organism processGO:004390130.010

arhgef1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.018
nervous system diseaseDOID:86300.015
disease of anatomical entityDOID:700.015
cardiovascular system diseaseDOID:128700.012
disease of cellular proliferationDOID:1456600.011