Danio rerio

0 known processes

syne2b

spectrin repeat containing, nuclear envelope 2b

(Aliases: id:ibd5137,wu:fc12c11,si:dkey-249p9.3,wu:fc62a06,fc12c11,wu:fc31e06)

syne2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.180
agingGO:000756820.122
locomotionGO:00400113130.119
Mouse
stem cell maintenanceGO:001982740.117
segmentationGO:0035282970.108
cellular nitrogen compound metabolic processGO:00346412900.105
regulation of response to stimulusGO:00485832690.097
cell morphogenesis involved in neuron differentiationGO:00486671630.097
chordate embryonic developmentGO:00430092710.095
embryonic organ developmentGO:00485683810.092
head developmentGO:00603223030.090
cellular biosynthetic processGO:00442492860.089
nitrogen compound metabolic processGO:00068073190.081
cell part morphogenesisGO:00329902460.075
regionalizationGO:00030022740.074
nucleic acid templated transcriptionGO:00976591810.074
cell projection organizationGO:00300302840.073
cellular macromolecule metabolic processGO:00442603910.072
digestive tract developmentGO:00485652650.072
embryonic pattern specificationGO:0009880440.066
brain developmentGO:00074202930.066
gastrulationGO:00073692080.065
anterior posterior pattern specificationGO:00099521520.065
regulation of biosynthetic processGO:00098892500.062
cell surface receptor signaling pathwayGO:00071663250.062
signal transductionGO:00071654550.060
embryonic organ morphogenesisGO:00485622740.060
ear developmentGO:00435831270.059
maintenance of locationGO:005123540.057
regulation of cellular biosynthetic processGO:00313262450.057
stem cell proliferationGO:007208940.056
positive regulation of cellular processGO:00485222010.056
Mouse
cell projection morphogenesisGO:00488582440.055
regulation of nucleic acid templated transcriptionGO:19035062130.055
cellular component movementGO:00069283350.055
Mouse
chemosensory behaviorGO:000763510.053
regulation of primary metabolic processGO:00800903110.053
aromatic compound biosynthetic processGO:00194382170.052
muscle cell differentiationGO:00426921390.050
transcription from rna polymerase ii promoterGO:0006366800.049
central nervous system developmentGO:00074173870.048
gene expressionGO:00104672520.048
organic cyclic compound biosynthetic processGO:19013622230.047
cell migrationGO:00164772370.046
Mouse
regulation of signalingGO:00230512350.046
regulation of multicellular organismal processGO:00512392770.046
generation of neuronsGO:00486993850.045
biosynthetic processGO:00090582940.045
heterocycle biosynthetic processGO:00181302150.045
axon developmentGO:00615641660.045
axon guidanceGO:0007411860.045
specification of symmetryGO:00097992040.044
nucleobase containing compound biosynthetic processGO:00346542050.044
lipid storageGO:001991510.044
neuron projection morphogenesisGO:00488121610.043
cellular component biogenesisGO:00440851780.043
neuron differentiationGO:00301823530.043
skin developmentGO:0043588540.042
sensory organ developmentGO:00074233930.042
digestive tract morphogenesisGO:00485462310.042
regulation of nitrogen compound metabolic processGO:00511712510.041
positive regulation of cell cycleGO:004578730.041
regulation of metabolic processGO:00192223590.041
somite developmentGO:0061053960.041
inner ear developmentGO:00488391260.041
regulation of multicellular organismal developmentGO:20000262230.040
organic cyclic compound metabolic processGO:19013603010.040
periodic partitioningGO:000736510.039
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.039
somatic muscle developmentGO:000752540.038
lateral inhibitionGO:004633110.037
enzyme linked receptor protein signaling pathwayGO:00071671060.037
regulation of cellular amine metabolic processGO:003323800.037
guanosine containing compound catabolic processGO:190106920.036
organic substance biosynthetic processGO:19015762890.036
neuron projection guidanceGO:0097485860.035
negative regulation of stem cell differentiationGO:200073720.035
sleepGO:003043110.035
organelle organizationGO:00069962270.034
Mouse
epidermal cell differentiationGO:0009913360.034
regulation of rna metabolic processGO:00512522240.034
regulation of cellular ketone metabolic processGO:001056570.033
tube morphogenesisGO:00352393490.033
primary neural tube formationGO:001402010.033
determination of bilateral symmetryGO:00098552040.033
phagocytosisGO:000690930.033
response to organic substanceGO:00100331530.032
deathGO:00162651210.032
cell morphogenesisGO:00009022890.032
single organism transportGO:00447652060.032
regulation of reproductive processGO:200024140.031
gtp metabolic processGO:004603940.031
ear morphogenesisGO:0042471640.031
protein demethylationGO:000648220.031
compound eye developmentGO:004874920.031
small molecule metabolic processGO:0044281770.030
regulation of cellular metabolic processGO:00313233200.030
gtp catabolic processGO:000618420.030
organonitrogen compound metabolic processGO:1901564740.030
regulation of transcription from rna polymerase ii promoterGO:00063571140.029
mesenchymal cell developmentGO:0014031780.029
positive regulation of nitrogen compound metabolic processGO:0051173690.029
vasculature developmentGO:00019442780.029
positive regulation of rna metabolic processGO:0051254590.028
regulation of macromolecule metabolic processGO:00602553170.028
tube closureGO:006060610.028
inner ear morphogenesisGO:0042472630.028
cell motilityGO:00488702440.028
Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.028
regulation of gene expressionGO:00104682650.028
cellular nitrogen compound biosynthetic processGO:00442712180.027
regulation of organ growthGO:004662030.027
endosomal transportGO:001619720.027
cellular amine metabolic processGO:004410620.027
regulation of peptidyl tyrosine phosphorylationGO:005073010.027
cardiac cell fate commitmentGO:006091110.026
oxoacid metabolic processGO:0043436310.026
regulation of localizationGO:00328791040.026
Mouse
stem cell divisionGO:001714510.026
hepaticobiliary system developmentGO:0061008980.026
response to external stimulusGO:00096052640.026
positive regulation of biological processGO:00485182530.026
Mouse
programmed cell deathGO:00125011190.026
outflow tract morphogenesisGO:000315110.026
transcription dna templatedGO:00063511810.025
positive regulation of gtp catabolic processGO:003312610.025
multicellular organism growthGO:003526440.025
regulation of cellular amino acid metabolic processGO:000652100.025
establishment of protein localization to organelleGO:007259440.025
cellular component assemblyGO:00226071700.025
macromolecule biosynthetic processGO:00090592270.024
guanosine containing compound metabolic processGO:190106840.024
pancreatic a cell developmentGO:000332220.024
regulation of macromolecule biosynthetic processGO:00105562250.024
regulation of locomotionGO:0040012550.024
Mouse
negative regulation of signalingGO:0023057960.024
behaviorGO:0007610740.024
development of primary female sexual characteristicsGO:004654540.024
heterocycle metabolic processGO:00464832900.024
tissue remodelingGO:004877140.023
regulation of cell activationGO:005086510.023
neuron developmentGO:00486662620.023
taxisGO:00423301090.023
cell morphogenesis involved in differentiationGO:00009041950.023
organelle assemblyGO:00709251100.023
cell projection assemblyGO:0030031640.023
nucleic acid metabolic processGO:00903042440.023
positive regulation of notch signaling pathwayGO:004574730.023
regulation of nucleoside metabolic processGO:000911820.023
nuclear transportGO:005116940.022
regulation of stem cell differentiationGO:200073640.022
positive regulation of catabolic processGO:000989640.022
carboxylic acid metabolic processGO:0019752220.022
female gonad developmentGO:000858540.022
epithelial tube morphogenesisGO:00605621480.022
cellular amino acid metabolic processGO:000652070.022
regulation of multicellular organism growthGO:004001440.022
nuclear importGO:005117030.022
cell fate specificationGO:0001708680.022
transportGO:00068102200.021
regulation of developmental processGO:00507932470.021
cellular component morphogenesisGO:00329893360.021
glial cell migrationGO:000834730.021
single organism metabolic processGO:00447102170.021
protein metabolic processGO:00195381830.021
embryo development ending in birth or egg hatchingGO:00097922710.021
golgi vesicle transportGO:004819330.021
female sex differentiationGO:004666040.021
rna metabolic processGO:00160702190.021
regulation of signal transductionGO:00099662250.021
protein localization to nucleusGO:003450430.021
Mouse
cellular ketone metabolic processGO:0042180110.021
positive regulation of transportGO:005105020.021
regulation of nucleobase containing compound metabolic processGO:00192192500.021
axonogenesisGO:00074091520.021
response to chemicalGO:00422213200.020
morphogenesis of an epitheliumGO:00020093330.020
negative regulation of protein phosphorylationGO:000193340.020
cell deathGO:00082191210.020
epithelial cell differentiationGO:00308551160.020
positive regulation of cellular catabolic processGO:003133130.020
macroautophagyGO:001623610.020
cellular response to extracellular stimulusGO:003166820.020
negative regulation of cytokine productionGO:000181810.020
regulation of protein complex assemblyGO:004325430.020
cellular aromatic compound metabolic processGO:00067252950.020
protein modification processGO:00362111000.019
epithelial cell morphogenesisGO:000338220.019
apoptotic processGO:00069151160.019
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.019
central nervous system neuron differentiationGO:0021953740.019
photoreceptor cell fate commitmentGO:004655210.019
membrane fusionGO:006102520.019
endoplasmic reticulum unfolded protein responseGO:003096820.019
cellular response to starvationGO:000926710.019
epidermis developmentGO:0008544480.019
phosphate containing compound metabolic processGO:00067961080.019
single organism organelle organizationGO:19025891990.019
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.019
positive regulation of cellular biosynthetic processGO:0031328680.019
cellular modified amino acid metabolic processGO:000657530.019
regulation of protein bindingGO:004339330.019
multi organism processGO:00517041340.018
cellular localizationGO:0051641970.018
Zebrafish Mouse
mesenchymal cell differentiationGO:0048762870.018
pronephros developmentGO:0048793690.018
eye developmentGO:00016542770.018
negative regulation of cell differentiationGO:0045596460.018
regulation of transcription dna templatedGO:00063552130.018
retinal ganglion cell axon guidanceGO:0031290350.018
activation of mapk activityGO:000018730.018
positive regulation of stem cell proliferationGO:200064810.018
forebrain developmentGO:0030900960.018
regulation of carbohydrate metabolic processGO:000610940.018
negative regulation of cellular processGO:00485232830.018
neural crest cell developmentGO:0014032620.018
regulation of cellular response to growth factor stimulusGO:0090287350.018
cellular macromolecule biosynthetic processGO:00346452240.018
neural crest formationGO:0014029140.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.018
organic acid metabolic processGO:0006082310.018
regulation of rna biosynthetic processGO:20011412130.018
neurotransmitter secretionGO:000726920.018
regulation of protein modification by small protein conjugation or removalGO:190332030.017
actin filament polymerizationGO:003004120.017
protein polymerizationGO:005125840.017
positive regulation of macromolecule biosynthetic processGO:0010557590.017
cellular response to external stimulusGO:007149620.017
rna biosynthetic processGO:00327741810.017
cognitionGO:005089010.017
negative regulation of cell communicationGO:0010648960.017
positive regulation of macromolecule metabolic processGO:0010604930.017
bmp signaling pathwayGO:0030509520.017
segment polarity determinationGO:000736710.017
positive regulation of cell differentiationGO:0045597300.017
peptide metabolic processGO:000651810.017
post golgi vesicle mediated transportGO:000689210.017
embryonic limb morphogenesisGO:003032620.017
regulation of bindingGO:005109830.017
protein targeting to nucleusGO:004474430.017
peptidyl serine modificationGO:001820920.016
regulation of cell communicationGO:00106462320.016
dorsal ventral pattern formationGO:00099531250.016
otic vesicle developmentGO:0071599420.016
otolith developmentGO:0048840320.016
mitochondrion organizationGO:000700540.016
otic vesicle morphogenesisGO:0071600340.016
determination of dorsal ventral asymmetryGO:0048262340.016
neurotransmitter transportGO:000683620.016
regulation of cell shapeGO:000836010.016
response to stressGO:00069502630.016
stem cell differentiationGO:00488631170.016
amine metabolic processGO:000930820.016
rna transportGO:005065820.016
germ line stem cell maintenanceGO:003071820.016
cellular response to chemical stimulusGO:00708871570.016
female meiotic divisionGO:000714320.016
protein polyubiquitinationGO:000020940.016
positive regulation of cell activationGO:005086710.015
positive regulation of epithelial cell differentiationGO:003085820.015
lamellipodium organizationGO:009758110.015
nucleocytoplasmic transportGO:000691340.015
phosphorus metabolic processGO:00067931090.015
neuroblast proliferationGO:000740520.015
cell fate commitmentGO:0045165990.015
nephron tubule morphogenesisGO:007207810.015
hormone secretionGO:004687920.015
pharyngeal muscle developmentGO:004328240.015
positive regulation of protein complex assemblyGO:003133420.015
g2 m transition of mitotic cell cycleGO:000008640.015
regulation of behaviorGO:0050795240.015
regulation of biological qualityGO:00650082630.015
Zebrafish
determination of left right symmetryGO:00073681790.015
single organism membrane fusionGO:004480120.015
protein localization to plasma membraneGO:007265910.015
muscle cell migrationGO:001481240.015
sensory organ morphogenesisGO:00905962000.015
mesoderm developmentGO:0007498880.015
lymphocyte proliferationGO:004665110.014
protein complex biogenesisGO:0070271300.014
regulation of cellular carbohydrate metabolic processGO:001067540.014
urogenital system developmentGO:0001655970.014
liver developmentGO:0001889960.014
regulation of cellular component organizationGO:0051128860.014
single organism localizationGO:19025782250.014
Mouse
regulation of neural precursor cell proliferationGO:200017730.014
neural tube patterningGO:0021532330.014
regulation of filopodium assemblyGO:005148920.014
antimicrobial humoral responseGO:001973020.014
negative regulation of catabolic processGO:000989530.014
single organism nuclear importGO:190259330.014
hormone transportGO:000991420.014
nuclear exportGO:005116810.014
leukocyte proliferationGO:007066110.014
chemotaxisGO:00069351040.014
connective tissue developmentGO:0061448990.014
production of molecular mediator of immune responseGO:000244020.014
midbrain developmentGO:0030901280.014
cellular response to nutrient levelsGO:003166920.014
regulation of cellular component movementGO:0051270550.014
Mouse
localization of cellGO:00516742440.014
Mouse
regulation of embryonic developmentGO:0045995470.014
establishment of endothelial barrierGO:006102830.014
positive regulation of metabolic processGO:00098931080.014
negative regulation of mapk cascadeGO:004340940.014
regulation of cell differentiationGO:00455951420.014
macromolecule modificationGO:00434121110.014
response to topologically incorrect proteinGO:003596620.014
protein import into nucleusGO:000660630.014
regulation of synapse organizationGO:005080730.014
positive regulation of cellular amine metabolic processGO:003324000.013
cellular amide metabolic processGO:004360340.013
establishment of synaptic vesicle localizationGO:009748010.013
regulation of epithelial cell proliferationGO:005067830.013
regulation of cell migrationGO:0030334400.013
Mouse
somitogenesisGO:0001756870.013
cytoskeleton dependent cytokinesisGO:006164030.013
blood vessel morphogenesisGO:00485142160.013
pancreas developmentGO:0031016840.013
response to endogenous stimulusGO:0009719830.013
branching morphogenesis of an epithelial tubeGO:0048754150.013
synaptic vesicle transportGO:004848910.013
protein targeting to vacuoleGO:000662310.013
negative regulation of kinase activityGO:003367340.013
developmental cell growthGO:0048588520.013
establishment of localizationGO:00512342440.013
Zebrafish Mouse
dna templated transcription elongationGO:000635430.013
lamellipodium assemblyGO:003003210.013
negative regulation of response to stimulusGO:00485851040.013
cartilage developmentGO:0051216960.013
regulation of myotube differentiationGO:001083020.013
regulation of epidermis developmentGO:004568220.013
positive regulation of nucleotide catabolic processGO:003081310.013
camera type eye developmentGO:00430102220.013
negative regulation of gliogenesisGO:001401410.013
regulation of cell deathGO:00109411030.013
positive regulation of reproductive processGO:200024320.013
immune system processGO:00023762410.013
developmental programmed cell deathGO:001062340.013
ameboidal type cell migrationGO:00016671430.013
Mouse
regulation of gtpase activityGO:004308720.013
positive regulation of cytoskeleton organizationGO:005149530.012
system processGO:00030081850.012
rhombomere 5 developmentGO:002157140.012
hindbrain developmentGO:0030902910.012
mesenchyme developmentGO:00604851270.012
regulation of cell motilityGO:2000145460.012
Mouse
positive regulation of gene expressionGO:0010628710.012
positive regulation of canonical wnt signaling pathwayGO:009026340.012
regulation of response to nutrient levelsGO:003210710.012
response to unfolded proteinGO:000698620.012
muscle structure developmentGO:00610611960.012
positive regulation of nucleoside metabolic processGO:004597910.012
meiotic cell cycle processGO:190304630.012
nucleic acid transportGO:005065720.012
immune system developmentGO:00025201910.012
response to hexoseGO:000974630.012
sensory perception of chemical stimulusGO:000760630.012
apoptotic process involved in developmentGO:190274220.012
otic vesicle formationGO:0030916270.012
regulation of cell projection assemblyGO:006049140.012
regulation of autophagyGO:001050630.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
regulation of synapse assemblyGO:005196330.012
positive regulation of secretionGO:005104710.012
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.012
regulation of purine nucleotide catabolic processGO:003312120.012
auditory receptor cell differentiationGO:0042491150.012
establishment of rna localizationGO:005123630.012
cellular component assembly involved in morphogenesisGO:00109271070.012
regulation of jun kinase activityGO:004350630.012
gastrulation with mouth forming secondGO:0001702440.012
extrinsic apoptotic signaling pathwayGO:009719130.012
response to drugGO:004249330.012
embryonic eye morphogenesisGO:0048048300.011
positive regulation of secretion by cellGO:190353210.011
neuronal stem cell maintenanceGO:009715020.011
negative regulation of epithelial cell proliferationGO:005068010.011
regulation of protein ubiquitinationGO:003139630.011
regulation of tube sizeGO:003515020.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
regulation of stem cell proliferationGO:007209120.011
positive regulation of cell adhesionGO:004578510.011
protein dephosphorylationGO:000647030.011
digestive system developmentGO:00551232890.011
glial cell proliferationGO:001400940.011
negative regulation of defense responseGO:003134820.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
regulation of neuronal synaptic plasticityGO:004816810.011
cranial ganglion developmentGO:006155030.011
response to lipidGO:0033993600.011
positive regulation of multicellular organismal processGO:0051240520.011
skeletal muscle fiber developmentGO:0048741350.011
oocyte maturationGO:000155640.011
negative regulation of muscle cell differentiationGO:005114810.011
peptidyl threonine modificationGO:001821010.011
nucleobase containing small molecule metabolic processGO:0055086320.011
positive regulation of gtpase activityGO:004354710.011
negative regulation of biological processGO:00485193040.011
muscle cell developmentGO:00550011150.011
regulation of gtp catabolic processGO:003312420.011
positive regulation of exocytosisGO:004592110.011
epidermal cell fate specificationGO:000995740.011
cell cycle g2 m phase transitionGO:004483940.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
regulation of dna templated transcription elongationGO:003278430.011
peptide transportGO:001583310.011
autophagyGO:000691440.011
cell proliferation in forebrainGO:002184630.011
somatic stem cell maintenanceGO:003501910.011
b cell mediated immunityGO:001972430.011
negative regulation of blood vessel endothelial cell migrationGO:004353710.011
gabaergic neuron differentiationGO:009715420.011
male meiosisGO:000714020.011
type b pancreatic cell developmentGO:000332340.011
regulation of phGO:000688530.011
insulin like growth factor receptor signaling pathwayGO:004800940.011
i kappab kinase nf kappab signalingGO:000724940.011
response to glucoseGO:000974930.011
developmental growthGO:00485891660.011
positive regulation of protein kinase b signalingGO:005189710.011
response to organic cyclic compoundGO:0014070510.010
regulation of cytoplasmic transportGO:190364940.010
negative regulation of programmed cell deathGO:0043069580.010
regulation of nucleotide catabolic processGO:003081120.010
immune responseGO:0006955280.010
positive regulation of blood circulationGO:190352420.010
muscle fiber developmentGO:0048747520.010
response to alkaloidGO:004327920.010
gland developmentGO:00487321430.010
positive regulation of multi organism processGO:004390230.010
response to vitaminGO:003327330.010
receptor internalizationGO:003162320.010
stem cell developmentGO:0048864820.010
positive regulation of biosynthetic processGO:0009891680.010
regulation of blood vessel sizeGO:005088020.010
carbohydrate derivative metabolic processGO:1901135610.010
regulation of molecular functionGO:0065009700.010
regulation of apoptotic processGO:0042981980.010
response to carbohydrateGO:000974330.010
regulation of protein catabolic processGO:004217610.010
regulation of cell morphogenesis involved in differentiationGO:0010769380.010
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.010
carbohydrate homeostasisGO:003350010.010
cellular carbohydrate metabolic processGO:004426240.010

syne2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.031
cardiovascular system diseaseDOID:128700.027
nervous system diseaseDOID:86300.013
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
disease of metabolismDOID:001466700.012
heart diseaseDOID:11400.010