| embryo development ending in birth or egg hatching | GO:0009792 | 271 | 0.637 | Worm |
| larval development | GO:0002164 | 2 | 0.597 | Worm |
| cellular protein catabolic process | GO:0044257 | 4 | 0.590 | Yeast |
| modification dependent macromolecule catabolic process | GO:0043632 | 3 | 0.580 | Yeast |
| single fertilization | GO:0007338 | 3 | 0.457 | |
| cellular macromolecule metabolic process | GO:0044260 | 391 | 0.425 | Yeast |
| modification dependent protein catabolic process | GO:0019941 | 3 | 0.420 | Yeast |
| proteasomal protein catabolic process | GO:0010498 | 2 | 0.420 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 3 | 0.397 | Yeast |
| mitotic nuclear division | GO:0007067 | 18 | 0.337 | Fly |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 3 | 0.300 | Yeast |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 2 | 0.258 | |
| aging | GO:0007568 | 2 | 0.255 | Worm |
| response to stress | GO:0006950 | 263 | 0.239 | |
| regulation of transcription elongation from rna polymerase ii promoter | GO:0034243 | 3 | 0.234 | |
| cellular protein metabolic process | GO:0044267 | 129 | 0.199 | Yeast |
| macromolecule catabolic process | GO:0009057 | 15 | 0.178 | Yeast |
| organic substance catabolic process | GO:1901575 | 28 | 0.174 | Yeast |
| protein metabolic process | GO:0019538 | 183 | 0.160 | Yeast Fly |
| locomotion | GO:0040011 | 313 | 0.159 | Worm |
| ncrna catabolic process | GO:0034661 | 1 | 0.158 | |
| nitrogen compound metabolic process | GO:0006807 | 319 | 0.149 | |
| cellular response to dna damage stimulus | GO:0006974 | 24 | 0.146 | |
| cellular macromolecule catabolic process | GO:0044265 | 12 | 0.130 | Yeast |
| reproductive process | GO:0022414 | 40 | 0.127 | |
| spindle assembly involved in mitosis | GO:0090307 | 1 | 0.116 | |
| regulation of gene expression | GO:0010468 | 265 | 0.113 | |
| fertilization | GO:0009566 | 3 | 0.104 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 3 | 0.102 | |
| rrna catabolic process | GO:0016075 | 1 | 0.090 | |
| regulation of metabolic process | GO:0019222 | 359 | 0.083 | |
| dna templated transcription elongation | GO:0006354 | 3 | 0.078 | |
| positive regulation of protein complex assembly | GO:0031334 | 2 | 0.077 | |
| nucleic acid metabolic process | GO:0090304 | 244 | 0.076 | |
| developmental process involved in reproduction | GO:0003006 | 27 | 0.076 | |
| mitotic dna integrity checkpoint | GO:0044774 | 4 | 0.075 | |
| cell cell recognition | GO:0009988 | 1 | 0.073 | |
| dna templated transcription initiation | GO:0006352 | 1 | 0.070 | |
| single organism reproductive process | GO:0044702 | 40 | 0.068 | |
| proteolysis | GO:0006508 | 38 | 0.067 | Yeast Fly |
| regulation of macromolecule metabolic process | GO:0060255 | 317 | 0.067 | |
| heterocycle metabolic process | GO:0046483 | 290 | 0.066 | |
| negative regulation of gene expression | GO:0010629 | 65 | 0.065 | |
| cellular biosynthetic process | GO:0044249 | 286 | 0.063 | |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 1 | 0.060 | |
| regulation of dna templated transcription elongation | GO:0032784 | 3 | 0.059 | |
| nucleobase containing compound biosynthetic process | GO:0034654 | 205 | 0.058 | |
| protein complex assembly | GO:0006461 | 30 | 0.058 | Yeast |
| signal transduction | GO:0007165 | 455 | 0.057 | |
| regulation of primary metabolic process | GO:0080090 | 311 | 0.056 | |
| transcription elongation from rna polymerase ii promoter | GO:0006368 | 3 | 0.052 | |
| cellular protein modification process | GO:0006464 | 100 | 0.051 | |
| spindle assembly | GO:0051225 | 2 | 0.050 | |
| reproduction | GO:0000003 | 40 | 0.049 | Worm |
| mitotic g2 dna damage checkpoint | GO:0007095 | 3 | 0.049 | |
| single organism organelle organization | GO:1902589 | 199 | 0.049 | Fly |
| regulation of protein catabolic process | GO:0042176 | 1 | 0.049 | |
| embryonic skeletal system morphogenesis | GO:0048704 | 93 | 0.048 | |
| protein modification process | GO:0036211 | 100 | 0.047 | |
| catabolic process | GO:0009056 | 32 | 0.047 | Yeast |
| chordate embryonic development | GO:0043009 | 271 | 0.046 | |
| macromolecular complex subunit organization | GO:0043933 | 74 | 0.045 | Yeast |
| positive regulation of cellular process | GO:0048522 | 201 | 0.045 | |
| organic substance biosynthetic process | GO:1901576 | 289 | 0.044 | |
| cellular nitrogen compound metabolic process | GO:0034641 | 290 | 0.044 | |
| regulation of response to stimulus | GO:0048583 | 269 | 0.044 | |
| cell cycle process | GO:0022402 | 53 | 0.044 | Fly |
| macromolecule biosynthetic process | GO:0009059 | 227 | 0.044 | |
| cellular protein complex assembly | GO:0043623 | 19 | 0.044 | Yeast |
| single organism metabolic process | GO:0044710 | 217 | 0.044 | |
| cellular component assembly | GO:0022607 | 170 | 0.044 | Yeast |
| cellular component biogenesis | GO:0044085 | 178 | 0.043 | Yeast |
| gene expression | GO:0010467 | 252 | 0.042 | |
| protein modification by small protein removal | GO:0070646 | 1 | 0.042 | |
| regulation of biosynthetic process | GO:0009889 | 250 | 0.042 | |
| mitotic cell cycle | GO:0000278 | 64 | 0.041 | Fly |
| macromolecular complex assembly | GO:0065003 | 35 | 0.040 | Yeast |
| protein complex subunit organization | GO:0071822 | 46 | 0.040 | Yeast |
| negative regulation of macromolecule metabolic process | GO:0010605 | 76 | 0.039 | |
| pronuclear migration | GO:0035046 | 1 | 0.038 | |
| negative regulation of metabolic process | GO:0009892 | 86 | 0.038 | |
| positive regulation of catabolic process | GO:0009896 | 4 | 0.038 | |
| positive regulation of dna templated transcription elongation | GO:0032786 | 1 | 0.038 | |
| regulation of cellular metabolic process | GO:0031323 | 320 | 0.038 | |
| cellular macromolecular complex assembly | GO:0034622 | 24 | 0.036 | Yeast |
| regulation of protein complex assembly | GO:0043254 | 3 | 0.036 | |
| protein n linked glycosylation | GO:0006487 | 1 | 0.036 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 4 | 0.035 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 1 | 0.035 | |
| nuclear export | GO:0051168 | 1 | 0.035 | |
| sensory organ development | GO:0007423 | 393 | 0.034 | |
| protein secretion | GO:0009306 | 1 | 0.034 | |
| transport | GO:0006810 | 220 | 0.034 | |
| positive regulation of gtp catabolic process | GO:0033126 | 1 | 0.033 | |
| protein catabolic process | GO:0030163 | 7 | 0.033 | Yeast |
| response to chemical | GO:0042221 | 320 | 0.033 | |
| rna biosynthetic process | GO:0032774 | 181 | 0.032 | |
| gtp metabolic process | GO:0046039 | 4 | 0.032 | |
| protein polymerization | GO:0051258 | 4 | 0.031 | |
| central nervous system development | GO:0007417 | 387 | 0.031 | |
| organelle assembly | GO:0070925 | 110 | 0.031 | |
| multi organism process | GO:0051704 | 134 | 0.031 | |
| organic cyclic compound metabolic process | GO:1901360 | 301 | 0.030 | |
| regulation of transcription dna templated | GO:0006355 | 213 | 0.030 | |
| small molecule metabolic process | GO:0044281 | 77 | 0.030 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 4 | 0.030 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 213 | 0.030 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 69 | 0.029 | |
| cell fate commitment | GO:0045165 | 99 | 0.029 | |
| guanosine containing compound catabolic process | GO:1901069 | 2 | 0.029 | |
| lateral inhibition | GO:0046331 | 1 | 0.028 | |
| cell motility | GO:0048870 | 244 | 0.028 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 4 | 0.028 | |
| cellular response to stress | GO:0033554 | 62 | 0.027 | |
| organonitrogen compound metabolic process | GO:1901564 | 74 | 0.027 | |
| regulation of macromolecule biosynthetic process | GO:0010556 | 225 | 0.027 | |
| cell cycle | GO:0007049 | 93 | 0.027 | Fly |
| gtp catabolic process | GO:0006184 | 2 | 0.026 | |
| atp catabolic process | GO:0006200 | 4 | 0.026 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 1 | 0.026 | |
| heterocycle catabolic process | GO:0046700 | 15 | 0.026 | |
| heterocycle biosynthetic process | GO:0018130 | 215 | 0.026 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 2 | 0.026 | |
| regulation of molecular function | GO:0065009 | 70 | 0.025 | |
| skeletal system development | GO:0001501 | 181 | 0.025 | |
| regulation of signal transduction | GO:0009966 | 225 | 0.025 | |
| regulation of nucleobase containing compound metabolic process | GO:0019219 | 250 | 0.025 | |
| cellular aromatic compound metabolic process | GO:0006725 | 295 | 0.024 | |
| cellular macromolecule biosynthetic process | GO:0034645 | 224 | 0.024 | |
| aromatic compound biosynthetic process | GO:0019438 | 217 | 0.024 | |
| eye development | GO:0001654 | 277 | 0.024 | |
| nuclear migration | GO:0007097 | 3 | 0.024 | |
| mitotic cell cycle process | GO:1903047 | 48 | 0.024 | Fly |
| embryonic skeletal system development | GO:0048706 | 97 | 0.023 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 80 | 0.023 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 68 | 0.023 | |
| cytokinesis | GO:0000910 | 3 | 0.023 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 1 | 0.023 | |
| mitotic dna damage checkpoint | GO:0044773 | 4 | 0.022 | |
| organelle organization | GO:0006996 | 227 | 0.022 | Fly |
| biosynthetic process | GO:0009058 | 294 | 0.022 | |
| transcription dna templated | GO:0006351 | 181 | 0.022 | |
| embryonic cranial skeleton morphogenesis | GO:0048701 | 90 | 0.022 | |
| positive regulation of cellular catabolic process | GO:0031331 | 3 | 0.022 | |
| glial cell development | GO:0021782 | 20 | 0.022 | |
| organic cyclic compound biosynthetic process | GO:1901362 | 223 | 0.021 | |
| cell part morphogenesis | GO:0032990 | 246 | 0.021 | |
| regulation of cell communication | GO:0010646 | 232 | 0.021 | |
| cellular nitrogen compound biosynthetic process | GO:0044271 | 218 | 0.021 | |
| negative regulation of biological process | GO:0048519 | 304 | 0.021 | |
| negative regulation of cellular process | GO:0048523 | 283 | 0.020 | |
| protein complex biogenesis | GO:0070271 | 30 | 0.020 | Yeast |
| sexual reproduction | GO:0019953 | 36 | 0.020 | |
| meiotic nuclear division | GO:0007126 | 4 | 0.020 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 1 | 0.020 | |
| meiotic spindle organization | GO:0000212 | 1 | 0.019 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 2 | 0.019 | |
| camera type eye development | GO:0043010 | 222 | 0.019 | |
| regulation of biological quality | GO:0065008 | 263 | 0.019 | |
| regulation of nitrogen compound metabolic process | GO:0051171 | 251 | 0.019 | |
| head development | GO:0060322 | 303 | 0.019 | |
| mitochondrion organization | GO:0007005 | 4 | 0.019 | |
| rna metabolic process | GO:0016070 | 219 | 0.019 | |
| gene silencing by rna | GO:0031047 | 4 | 0.019 | |
| cellular localization | GO:0051641 | 97 | 0.019 | |
| g2 dna damage checkpoint | GO:0031572 | 3 | 0.019 | |
| regulation of cellular macromolecule biosynthetic process | GO:2000112 | 222 | 0.019 | |
| regulation of cell cycle | GO:0051726 | 52 | 0.019 | Fly |
| regulation of nucleoside metabolic process | GO:0009118 | 2 | 0.018 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 4 | 0.018 | |
| protein acylation | GO:0043543 | 3 | 0.018 | |
| regulation of rna biosynthetic process | GO:2001141 | 213 | 0.018 | |
| regulation of cellular biosynthetic process | GO:0031326 | 245 | 0.018 | |
| establishment of localization in cell | GO:0051649 | 77 | 0.018 | |
| establishment of protein localization to organelle | GO:0072594 | 4 | 0.018 | |
| cell projection morphogenesis | GO:0048858 | 244 | 0.018 | |
| vasculature development | GO:0001944 | 278 | 0.018 | |
| regulation of binding | GO:0051098 | 3 | 0.018 | |
| regulation of proteolysis | GO:0030162 | 24 | 0.017 | |
| protein stabilization | GO:0050821 | 2 | 0.017 | |
| nucleobase containing compound metabolic process | GO:0006139 | 274 | 0.017 | |
| regulation of inflammatory response | GO:0050727 | 2 | 0.017 | |
| organic substance transport | GO:0071702 | 58 | 0.017 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 3 | 0.016 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 32 | 0.016 | |
| gamete generation | GO:0007276 | 33 | 0.016 | |
| protein acetylation | GO:0006473 | 2 | 0.016 | |
| negative regulation of neural precursor cell proliferation | GO:2000178 | 1 | 0.016 | |
| regulation of cellular protein catabolic process | GO:1903362 | 1 | 0.016 | |
| regulation of response to external stimulus | GO:0032101 | 31 | 0.016 | |
| regulation of cellular amine metabolic process | GO:0033238 | 0 | 0.016 | |
| cell morphogenesis | GO:0000902 | 289 | 0.016 | |
| mitotic g2 m transition checkpoint | GO:0044818 | 3 | 0.016 | |
| response to external stimulus | GO:0009605 | 264 | 0.016 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 7 | 0.015 | |
| lipid storage | GO:0019915 | 1 | 0.015 | |
| mitochondrial transport | GO:0006839 | 2 | 0.015 | |
| mesenchymal cell differentiation | GO:0048762 | 87 | 0.015 | |
| programmed cell death | GO:0012501 | 119 | 0.015 | |
| intestinal cholesterol absorption | GO:0030299 | 2 | 0.015 | |
| cellular amine metabolic process | GO:0044106 | 2 | 0.014 | |
| multicellular organismal reproductive process | GO:0048609 | 35 | 0.014 | |
| cell migration | GO:0016477 | 237 | 0.014 | |
| amine metabolic process | GO:0009308 | 2 | 0.014 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 0 | 0.014 | |
| phagocytosis | GO:0006909 | 3 | 0.014 | |
| brain development | GO:0007420 | 293 | 0.014 | |
| positive regulation of gtpase activity | GO:0043547 | 1 | 0.014 | |
| negative regulation of immune response | GO:0050777 | 2 | 0.014 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 59 | 0.014 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 93 | 0.013 | |
| regulation of endopeptidase activity | GO:0052548 | 23 | 0.013 | |
| regulation of peptidase activity | GO:0052547 | 23 | 0.013 | |
| rna catabolic process | GO:0006401 | 7 | 0.013 | |
| regulation of postsynaptic membrane potential | GO:0060078 | 1 | 0.013 | |
| response to organic substance | GO:0010033 | 153 | 0.013 | |
| organelle localization | GO:0051640 | 49 | 0.012 | |
| cell death | GO:0008219 | 121 | 0.012 | |
| regulation of nucleotide catabolic process | GO:0030811 | 2 | 0.012 | |
| negative regulation of cellular metabolic process | GO:0031324 | 77 | 0.012 | |
| cellular catabolic process | GO:0044248 | 27 | 0.012 | Yeast |
| regulation of signaling | GO:0023051 | 235 | 0.012 | |
| regulation of gene expression epigenetic | GO:0040029 | 11 | 0.012 | |
| positive regulation of biological process | GO:0048518 | 253 | 0.012 | |
| death | GO:0016265 | 121 | 0.012 | |
| regulation of gtpase activity | GO:0043087 | 2 | 0.012 | |
| protein import | GO:0017038 | 3 | 0.011 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 1 | 0.011 | |
| positive regulation of cellular metabolic process | GO:0031325 | 94 | 0.011 | |
| cell cycle g1 s phase transition | GO:0044843 | 1 | 0.011 | |
| positive regulation of endopeptidase activity | GO:0010950 | 10 | 0.011 | |
| cell cell signaling | GO:0007267 | 52 | 0.011 | |
| maintenance of location | GO:0051235 | 4 | 0.011 | |
| response to alkaloid | GO:0043279 | 2 | 0.011 | |
| regulation of gtp catabolic process | GO:0033124 | 2 | 0.011 | |
| zymogen activation | GO:0031638 | 3 | 0.011 | |
| generation of neurons | GO:0048699 | 385 | 0.011 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 14 | 0.011 | |
| cell surface receptor signaling pathway | GO:0007166 | 325 | 0.011 | |
| single organism localization | GO:1902578 | 225 | 0.011 | |
| female sex differentiation | GO:0046660 | 4 | 0.010 | |
| protein localization to nucleus | GO:0034504 | 3 | 0.010 | |
| dna repair | GO:0006281 | 6 | 0.010 | |
| growth | GO:0040007 | 174 | 0.010 | |
| regulation of mitotic cell cycle | GO:0007346 | 25 | 0.010 | Fly |
| regulation of canonical wnt signaling pathway | GO:0060828 | 34 | 0.010 | |
| microtubule polymerization | GO:0046785 | 2 | 0.010 | |
| cellular ketone metabolic process | GO:0042180 | 11 | 0.010 | |
