Danio rerio

24 known processes

shox2

short stature homeobox 2

(Aliases: zgc:65884,MGC65884,zgc:77344)

shox2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
central nervous system developmentGO:00074173870.395
neuron differentiationGO:00301823530.207
eye developmentGO:00016542770.188
generation of neuronsGO:00486993850.163
regulation of developmental processGO:00507932470.140
head developmentGO:00603223030.117
brain developmentGO:00074202930.114
cellular macromolecule metabolic processGO:00442603910.096
heterocycle biosynthetic processGO:00181302150.094
regulation of multicellular organismal processGO:00512392770.091
cell morphogenesis involved in neuron differentiationGO:00486671630.088
larval developmentGO:000216420.087
camera type eye developmentGO:00430102220.087
neuron developmentGO:00486662620.085
cell projection organizationGO:00300302840.077
cell part morphogenesisGO:00329902460.075
organic substance biosynthetic processGO:19015762890.072
morphogenesis of an epitheliumGO:00020093330.071
embryonic organ developmentGO:00485683810.070
agingGO:000756820.070
negative regulation of biological processGO:00485193040.069
regulation of cell differentiationGO:00455951420.068
regulation of neuron projection developmentGO:0010975400.068
neuron projection developmentGO:00311751800.067
response to chemicalGO:00422213200.067
axonogenesisGO:00074091520.064
hindbrain developmentGO:0030902910.063
cellular component morphogenesisGO:00329893360.060
multicellular organism growthGO:003526440.060
biosynthetic processGO:00090582940.059
regulation of nitrogen compound metabolic processGO:00511712510.059
sensory organ developmentGO:00074233930.059
cellular nitrogen compound biosynthetic processGO:00442712180.058
embryonic organ morphogenesisGO:00485622740.056
specification of symmetryGO:00097992040.055
cartilage developmentGO:0051216960.054
cell projection morphogenesisGO:00488582440.054
regulation of rna metabolic processGO:00512522240.053
neuron projection morphogenesisGO:00488121610.053
regulation of neuron differentiationGO:0045664560.053
regulation of transcription dna templatedGO:00063552130.050
regulation of neurogenesisGO:0050767870.049
positive regulation of cellular processGO:00485222010.049
macromolecule biosynthetic processGO:00090592270.048
regulation of signalingGO:00230512350.048
regulation of macromolecule metabolic processGO:00602553170.047
rna biosynthetic processGO:00327741810.047
cellular macromolecule biosynthetic processGO:00346452240.046
rna metabolic processGO:00160702190.046
developmental growth involved in morphogenesisGO:0060560860.046
determination of bilateral symmetryGO:00098552040.045
regulation of cell developmentGO:00602841000.045
nitrogen compound metabolic processGO:00068073190.044
tissue remodelingGO:004877140.044
negative regulation of cellular processGO:00485232830.044
regulation of nervous system developmentGO:0051960900.043
organic cyclic compound biosynthetic processGO:19013622230.043
determination of left right symmetryGO:00073681790.043
regulation of nucleic acid templated transcriptionGO:19035062130.041
axon developmentGO:00615641660.041
forebrain developmentGO:0030900960.041
transcription dna templatedGO:00063511810.040
nucleic acid templated transcriptionGO:00976591810.040
neuron projection extensionGO:1990138450.039
regulation of macromolecule biosynthetic processGO:00105562250.039
axon guidanceGO:0007411860.039
cellular component movementGO:00069283350.039
cell morphogenesis involved in differentiationGO:00009041950.038
nucleobase containing compound biosynthetic processGO:00346542050.038
skeletal system developmentGO:00015011810.038
central nervous system neuron differentiationGO:0021953740.038
regulation of metabolic processGO:00192223590.037
cellular biosynthetic processGO:00442492860.037
aromatic compound biosynthetic processGO:00194382170.037
axon extensionGO:0048675450.037
heterocycle metabolic processGO:00464832900.037
regulation of gene expressionGO:00104682650.037
negative regulation of developmental processGO:0051093650.037
retina development in camera type eyeGO:00600411460.036
hepaticobiliary system developmentGO:0061008980.036
regulation of cellular biosynthetic processGO:00313262450.035
signal transductionGO:00071654550.035
sensory organ morphogenesisGO:00905962000.035
regulation of anatomical structure morphogenesisGO:00226031300.035
regulation of primary metabolic processGO:00800903110.034
skin developmentGO:0043588540.034
nucleobase containing compound metabolic processGO:00061392740.034
endocrine system developmentGO:0035270650.034
organic cyclic compound metabolic processGO:19013603010.034
growthGO:00400071740.034
cellular amine metabolic processGO:004410620.034
developmental cell growthGO:0048588520.033
cell substrate adhesionGO:003158940.033
ear developmentGO:00435831270.033
positive regulation of biological processGO:00485182530.032
response to external stimulusGO:00096052640.032
positive regulation of transportGO:005105020.032
inner ear morphogenesisGO:0042472630.032
connective tissue developmentGO:0061448990.032
hematopoietic or lymphoid organ developmentGO:00485341910.031
cell morphogenesisGO:00009022890.031
localization of cellGO:00516742440.031
amine metabolic processGO:000930820.031
heart developmentGO:00075073130.031
regulation of cellular metabolic processGO:00313233200.031
vasculature developmentGO:00019442780.031
immune system processGO:00023762410.031
regulation of signal transductionGO:00099662250.031
regulation of multicellular organismal developmentGO:20000262230.030
regulation of biosynthetic processGO:00098892500.030
regulation of synapse assemblyGO:005196330.030
maintenance of locationGO:005123540.030
regulation of axonogenesisGO:0050770320.030
regulation of cell morphogenesis involved in differentiationGO:0010769380.029
nucleic acid metabolic processGO:00903042440.029
sensory system developmentGO:0048880760.029
immune system developmentGO:00025201910.029
camera type eye morphogenesisGO:00485931080.028
ectodermal placode morphogenesisGO:0071697320.028
homeostatic processGO:00425921420.028
retina morphogenesis in camera type eyeGO:0060042790.028
tube morphogenesisGO:00352393490.028
alternative mrna splicing via spliceosomeGO:000038010.028
gland developmentGO:00487321430.028
regulation of synapse organizationGO:005080730.028
cell surface receptor signaling pathwayGO:00071663250.027
liver developmentGO:0001889960.027
regulation of cellular macromolecule biosynthetic processGO:20001122220.027
regulation of reproductive processGO:200024140.027
regionalizationGO:00030022740.027
chordate embryonic developmentGO:00430092710.027
regulation of cell communicationGO:00106462320.027
regulation of cellular amino acid metabolic processGO:000652100.027
appendage developmentGO:0048736800.027
dorsal ventral pattern formationGO:00099531250.026
metencephalon developmentGO:0022037270.026
cellular response to xenobiotic stimulusGO:0071466350.026
inner ear developmentGO:00488391260.026
locomotionGO:00400113130.026
regulation of cellular ketone metabolic processGO:001056570.025
single organism metabolic processGO:00447102170.025
cell motilityGO:00488702440.024
somatic stem cell maintenanceGO:003501910.024
negative regulation of multicellular organismal processGO:0051241690.024
cell fate commitmentGO:0045165990.024
eye morphogenesisGO:00485921440.024
developmental growthGO:00485891660.024
gene expressionGO:00104672520.024
cell growthGO:0016049570.024
female gonad developmentGO:000858540.024
regulation of response to stimulusGO:00485832690.024
regulation of cellular amine metabolic processGO:003323800.023
cellular aromatic compound metabolic processGO:00067252950.023
chemotaxisGO:00069351040.023
rhombomere 5 developmentGO:002157140.023
meiotic nuclear divisionGO:000712640.023
regulation of nucleobase containing compound metabolic processGO:00192192500.023
stem cell maintenanceGO:001982740.023
regulation of axon extensionGO:0030516240.023
angiogenesisGO:00015251580.022
otolith developmentGO:0048840320.022
hemopoiesisGO:00300971830.022
cellular nitrogen compound metabolic processGO:00346412900.022
regulation of mrna splicing via spliceosomeGO:004802430.021
response to stressGO:00069502630.021
embryo development ending in birth or egg hatchingGO:00097922710.021
transcription from rna polymerase ii promoterGO:0006366800.021
regulation of rna biosynthetic processGO:20011412130.021
anterior posterior pattern specificationGO:00099521520.021
oxoacid metabolic processGO:0043436310.021
protein localization to plasma membraneGO:007265910.021
regulation of cell morphogenesisGO:0022604420.021
neuron projection guidanceGO:0097485860.021
diencephalon developmentGO:0021536580.021
blood vessel developmentGO:00015682460.021
regulation of tissue remodelingGO:003410320.021
positive regulation of cellular component biogenesisGO:004408930.020
positive regulation of cellular amino acid metabolic processGO:004576400.020
kupffer s vesicle developmentGO:0070121500.020
midbrain developmentGO:0030901280.020
establishment of protein localization to plasma membraneGO:009000210.020
ectodermal placode developmentGO:0071696370.019
regulation of biological qualityGO:00650082630.019
digestive tract developmentGO:00485652650.019
organic acid metabolic processGO:0006082310.019
cilium morphogenesisGO:0060271850.019
nuclear exportGO:005116810.019
phagocytosisGO:000690930.019
regulation of mrna processingGO:005068430.019
regulation of cell projection organizationGO:0031344440.019
regulation of phGO:000688530.019
regulation of cellular component organizationGO:0051128860.019
positive regulation of macromolecule metabolic processGO:0010604930.019
carboxylic acid metabolic processGO:0019752220.018
behaviorGO:0007610740.018
membrane fusionGO:006102520.018
cellular ketone metabolic processGO:0042180110.018
cellular response to nutrient levelsGO:003166920.018
neuron fate specificationGO:0048665200.018
digestive system developmentGO:00551232890.018
otic vesicle developmentGO:0071599420.018
regulation of tube sizeGO:003515020.018
organonitrogen compound metabolic processGO:1901564740.018
synaptic transmission cholinergicGO:000727140.018
establishment of localizationGO:00512342440.018
adult behaviorGO:003053420.018
stem cell differentiationGO:00488631170.018
cellular amide metabolic processGO:004360340.018
stem cell divisionGO:001714510.018
positive regulation of cellular amine metabolic processGO:003324000.018
synaptic growth at neuromuscular junctionGO:005112420.017
notochord developmentGO:0030903540.017
taxisGO:00423301090.017
single organism transportGO:00447652060.017
cellular response to starvationGO:000926710.017
cellular response to external stimulusGO:007149620.017
single organism localizationGO:19025782250.017
negative regulation of cell differentiationGO:0045596460.017
cellular response to extracellular stimulusGO:003166820.017
regulation of blood vessel sizeGO:005088020.017
regulation of dendrite developmentGO:005077330.017
response to xenobiotic stimulusGO:0009410450.017
oocyte maturationGO:000155640.016
peripheral nervous system developmentGO:0007422550.016
pectoral fin developmentGO:0033339500.016
cell migrationGO:00164772370.016
response to monosaccharideGO:003428430.016
neuron fate commitmentGO:0048663260.016
female sex differentiationGO:004666040.016
fin developmentGO:0033333770.016
cellular component assemblyGO:00226071700.016
lipid storageGO:001991510.016
cell agingGO:000756920.016
stem cell fate commitmentGO:004886510.015
germ line stem cell maintenanceGO:003071820.015
negative chemotaxisGO:005091910.015
response to carbohydrateGO:000974330.015
nuclear transportGO:005116940.015
protein metabolic processGO:00195381830.015
negative regulation of neurogenesisGO:0050768200.015
central nervous system neuron axonogenesisGO:0021955180.015
cellular carbohydrate metabolic processGO:004426240.015
regulation of protein complex assemblyGO:004325430.015
heart morphogenesisGO:00030071560.015
fibroblast growth factor receptor signaling pathwayGO:0008543220.015
regulation of wnt signaling pathwayGO:0030111530.015
system processGO:00030081850.015
lipid homeostasisGO:005508830.015
nucleocytoplasmic transportGO:000691340.015
regulation of alternative mrna splicing via spliceosomeGO:000038110.015
embryonic limb morphogenesisGO:003032620.015
lateral line developmentGO:0048882660.015
response to vitaminGO:003327330.015
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.015
regulation of protein localization to plasma membraneGO:190307610.015
response to uvGO:000941130.015
regulation of sequestering of calcium ionGO:005128240.014
negative regulation of nervous system developmentGO:0051961220.014
lateral line system developmentGO:0048925760.014
pancreas developmentGO:0031016840.014
regulation of bindingGO:005109830.014
regulation of cell motilityGO:2000145460.014
embryonic retina morphogenesis in camera type eyeGO:0060059220.014
cellular component biogenesisGO:00440851780.014
epithelial tube morphogenesisGO:00605621480.014
response to woundingGO:00096111160.014
regulation of bone remodelingGO:004685020.014
small molecule metabolic processGO:0044281770.014
positive regulation of cell cycleGO:004578730.014
positive regulation of catabolic processGO:000989640.014
regulation of extent of cell growthGO:0061387290.014
spinal cord developmentGO:0021510460.014
regulation of multicellular organism growthGO:004001440.014
positive regulation of biosynthetic processGO:0009891680.014
carbohydrate homeostasisGO:003350010.014
positive regulation of metabolic processGO:00098931080.014
neurotransmitter transportGO:000683620.014
regulation of establishment of protein localizationGO:007020140.014
cellular amino acid metabolic processGO:000652070.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
response to hexoseGO:000974630.014
embryonic skeletal system developmentGO:0048706970.014
epidermis developmentGO:0008544480.013
cellular response to chemical stimulusGO:00708871570.013
embryonic heart tube developmentGO:00350501330.013
embryonic skeletal system morphogenesisGO:0048704930.013
regulation of ion transmembrane transporter activityGO:003241220.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
cell deathGO:00082191210.013
mesenchyme developmentGO:00604851270.013
erk1 and erk2 cascadeGO:007037140.013
negative regulation of protein kinase activityGO:000646940.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
otic vesicle formationGO:0030916270.013
gastrulationGO:00073692080.013
development of primary female sexual characteristicsGO:004654540.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
negative regulation of signal transductionGO:0009968940.013
b cell activationGO:004211320.013
cell proliferationGO:0008283800.013
mitochondrion organizationGO:000700540.013
transportGO:00068102200.013
rhombomere 6 developmentGO:002157240.012
embryonic cranial skeleton morphogenesisGO:0048701900.012
wound healingGO:0042060900.012
positive regulation of cellular catabolic processGO:003133130.012
apoptotic processGO:00069151160.012
mechanosensory lateral line system developmentGO:0048881490.012
deathGO:00162651210.012
negative regulation of sequestering of calcium ionGO:005128340.012
regulation of cellular component movementGO:0051270550.012
regulation of transmembrane transporter activityGO:002289820.012
organelle organizationGO:00069962270.012
positive regulation of cell adhesionGO:004578510.012
oligodendrocyte differentiationGO:0048709230.012
negative regulation of cell communicationGO:0010648960.012
cell fate specificationGO:0001708680.012
negative regulation of apoptotic processGO:0043066550.012
release of sequestered calcium ion into cytosolGO:005120930.012
positive regulation of gene expressionGO:0010628710.012
mitotic cytokinesisGO:000028130.012
single organism organelle organizationGO:19025891990.012
negative regulation of protein phosphorylationGO:000193340.012
programmed cell deathGO:00125011190.012
response to nutrientGO:000758430.012
protein acylationGO:004354330.012
otic placode formationGO:0043049230.012
positive regulation of protein polymerizationGO:003227320.012
cellular response to fibroblast growth factor stimulusGO:0044344220.012
regulation of cell migrationGO:0030334400.012
establishment of protein localization to organelleGO:007259440.012
stem cell proliferationGO:007208940.011
regulation of meiotic cell cycleGO:005144510.011
negative regulation of kinase activityGO:003367340.011
regulation of muscle contractionGO:000693730.011
peptidyl serine modificationGO:001820920.011
regulation of cell activationGO:005086510.011
convergent extensionGO:00600261180.011
mitotic dna integrity checkpointGO:004477440.011
cytoskeleton dependent cytokinesisGO:006164030.011
digestive tract morphogenesisGO:00485462310.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
regulation of transporter activityGO:003240920.011
response to drugGO:004249330.011
nerve developmentGO:0021675450.011
ribonucleoside monophosphate catabolic processGO:000915840.011
embryonic pattern specificationGO:0009880440.011
cellular response to stressGO:0033554620.011
phosphatidylinositol 3 kinase signalingGO:001406520.011
protein targeting to membraneGO:000661210.011
regulation of endothelial cell proliferationGO:000193610.011
response to hydrogen peroxideGO:004254230.011
pectoral fin morphogenesisGO:0035138290.011
regulation of cell growthGO:0001558290.011
positive regulation of cytoskeleton organizationGO:005149530.011
bone remodelingGO:004684920.011
negative regulation of response to stimulusGO:00485851040.011
single organism membrane fusionGO:004480120.011
stem cell developmentGO:0048864820.011
regulation of cell sizeGO:0008361290.011
negative regulation of map kinase activityGO:004340720.011
sequestering of metal ionGO:005123830.011
negative regulation of cell developmentGO:0010721260.011
gtp catabolic processGO:000618420.011
regulation of cell shapeGO:000836010.011
positive regulation of nucleic acid templated transcriptionGO:1903508570.011
atp catabolic processGO:000620040.011
neurotransmitter secretionGO:000726920.011
response to organic substanceGO:00100331530.010
protein polymerizationGO:005125840.010
chemosensory behaviorGO:000763510.010
peptide metabolic processGO:000651810.010
guanosine containing compound catabolic processGO:190106920.010
spermatid developmentGO:000728620.010
negative regulation of metabolic processGO:0009892860.010
cranial nerve developmentGO:0021545420.010
embryonic skeletal joint morphogenesisGO:006027230.010
positive regulation of transcription dna templatedGO:0045893570.010
response to glucocorticoidGO:005138410.010
amyloid precursor protein metabolic processGO:004298210.010
response to glucoseGO:000974930.010
wnt signaling pathwayGO:0016055800.010
positive regulation of cellular metabolic processGO:0031325940.010
ear morphogenesisGO:0042471640.010
regulation of locomotionGO:0040012550.010
central nervous system neuron developmentGO:0021954290.010
protein importGO:001703830.010
posterior lateral line system developmentGO:0048915460.010
negative regulation of signalingGO:0023057960.010
regulation of cytokine productionGO:000181730.010
sequestering of calcium ionGO:005120830.010
negative regulation of cell projection organizationGO:003134590.010
otic vesicle morphogenesisGO:0071600340.010
regulation of transcription from rna polymerase ii promoterGO:00063571140.010
multi organism processGO:00517041340.010

shox2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
disease of cellular proliferationDOID:1456600.025
cancerDOID:16200.025
disease of metabolismDOID:001466700.025
organ system cancerDOID:005068600.020
musculoskeletal system diseaseDOID:1700.018
nervous system diseaseDOID:86300.015
immune system diseaseDOID:291400.012