Danio rerio

0 known processes

itpr1a

inositol 1,4,5-triphosphate receptor, type 1a

itpr1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
localization of cellGO:00516742440.133
larval developmentGO:000216420.118
cellular component movementGO:00069283350.087
signal transductionGO:00071654550.085
Mouse Fly
cell projection organizationGO:00300302840.075
lipid homeostasisGO:005508830.075
Fly
cell migrationGO:00164772370.071
maintenance of locationGO:005123540.069
Mouse Fly
female sex differentiationGO:004666040.068
response to stressGO:00069502630.068
Mouse Fly
immune system processGO:00023762410.065
regulation of synapse assemblyGO:005196330.065
development of primary female sexual characteristicsGO:004654540.065
protein heterooligomerizationGO:005129110.062
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.060
negative regulation of cellular processGO:00485232830.057
Mouse Fly
regulation of multicellular organism growthGO:004001440.054
neuron differentiationGO:00301823530.053
regulation of synapse organizationGO:005080730.052
cell surface receptor signaling pathwayGO:00071663250.052
Fly
lipid storageGO:001991510.048
head developmentGO:00603223030.045
Fly
cell motilityGO:00488702440.043
female gonad developmentGO:000858540.043
regulation of developmental processGO:00507932470.043
positive regulation of transportGO:005105020.042
taxisGO:00423301090.042
response to chemicalGO:00422213200.042
regulation of cell shapeGO:000836010.041
central nervous system developmentGO:00074173870.041
Fly
multicellular organism growthGO:003526440.041
phagocytosisGO:000690930.041
digestive tract morphogenesisGO:00485462310.040
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.038
Fly
neuron developmentGO:00486662620.037
response to external stimulusGO:00096052640.037
Fly
adult behaviorGO:003053420.037
Fly
regulation of multicellular organismal processGO:00512392770.037
cognitionGO:005089010.036
blood vessel developmentGO:00015682460.036
agingGO:000756820.035
cell morphogenesisGO:00009022890.035
negative regulation of biological processGO:00485193040.034
Mouse Fly
regulation of cellular ketone metabolic processGO:001056570.034
developmental growthGO:00485891660.033
tube morphogenesisGO:00352393490.033
gtp metabolic processGO:004603940.033
autophagyGO:000691440.033
lateral inhibitionGO:004633110.032
cell projection morphogenesisGO:00488582440.031
establishment of protein localization to organelleGO:007259440.031
embryonic organ developmentGO:00485683810.031
nuclear transportGO:005116940.031
regulation of signalingGO:00230512350.031
establishment of localizationGO:00512342440.031
Mouse Fly
macromolecule biosynthetic processGO:00090592270.031
generation of neuronsGO:00486993850.030
gtp catabolic processGO:000618420.029
aromatic compound biosynthetic processGO:00194382170.029
digestive system developmentGO:00551232890.029
regulation of signal transductionGO:00099662250.028
blood vessel morphogenesisGO:00485142160.028
regulation of cell activationGO:005086510.028
organonitrogen compound metabolic processGO:1901564740.028
nuclear migrationGO:000709730.028
mesenchyme developmentGO:00604851270.027
actin filament based movementGO:003004810.027
actin polymerization or depolymerizationGO:000815420.027
vasculature developmentGO:00019442780.027
cellular response to external stimulusGO:007149620.027
negative regulation of ras protein signal transductionGO:004658010.027
morphogenesis of an epitheliumGO:00020093330.027
ribonucleoside monophosphate catabolic processGO:000915840.027
gastrulationGO:00073692080.027
modification dependent macromolecule catabolic processGO:004363230.027
nucleoside monophosphate catabolic processGO:000912540.027
neuron projection developmentGO:00311751800.026
regulation of transcription dna templatedGO:00063552130.026
purine ribonucleoside monophosphate catabolic processGO:000916940.026
purine nucleoside monophosphate catabolic processGO:000912840.026
cellular component morphogenesisGO:00329893360.026
carboxylic acid metabolic processGO:0019752220.026
axonogenesisGO:00074091520.026
protein targeting to nucleusGO:004474430.025
ovulation cycleGO:004269820.025
regulation of biological qualityGO:00650082630.025
Mouse Fly
regulation of dendrite developmentGO:005077330.025
convergent extension involved in gastrulationGO:0060027710.024
regulation of protein import into nucleusGO:004230620.024
regulation of inflammatory responseGO:005072720.024
cellular ketone metabolic processGO:0042180110.024
sensory perception of chemical stimulusGO:000760630.024
Fly
locomotionGO:00400113130.024
synaptic growth at neuromuscular junctionGO:005112420.024
regulation of cell differentiationGO:00455951420.023
response to woundingGO:00096111160.023
fertilizationGO:000956630.023
regulation of cytoplasmic transportGO:190364940.023
specification of symmetryGO:00097992040.023
amine metabolic processGO:000930820.022
determination of left right symmetryGO:00073681790.022
positive regulation of cellular component biogenesisGO:004408930.022
organelle fusionGO:004828430.022
axon developmentGO:00615641660.022
system processGO:00030081850.022
Fly
regulation of establishment of protein localizationGO:007020140.022
single organism membrane fusionGO:004480120.022
regulation of cytokine productionGO:000181730.022
organic acid metabolic processGO:0006082310.022
cellular macromolecule metabolic processGO:00442603910.022
guanosine containing compound metabolic processGO:190106840.022
cellular response to chemical stimulusGO:00708871570.022
hemopoiesisGO:00300971830.022
nucleocytoplasmic transportGO:000691340.022
transportGO:00068102200.022
Mouse Fly
guanosine containing compound catabolic processGO:190106920.022
response to other organismGO:0051707970.022
heart developmentGO:00075073130.022
cellular component biogenesisGO:00440851780.022
positive regulation of cellular amino acid metabolic processGO:004576400.021
chemotaxisGO:00069351040.021
regulation of cellular amine metabolic processGO:003323800.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.021
cell substrate adhesionGO:003158940.021
protein localization to nucleusGO:003450430.021
estrogen metabolic processGO:000821020.021
oxoacid metabolic processGO:0043436310.021
regulation of protein transportGO:005122330.021
protein dephosphorylationGO:000647030.021
internal protein amino acid acetylationGO:000647520.021
embryonic heart tube developmentGO:00350501330.021
adherens junction organizationGO:003433240.021
regulation of cellular component organizationGO:0051128860.021
digestive tract developmentGO:00485652650.021
protein homooligomerizationGO:005126030.020
regulation of rna biosynthetic processGO:20011412130.020
enzyme linked receptor protein signaling pathwayGO:00071671060.020
positive regulation of cell cycleGO:004578730.020
embryonic organ morphogenesisGO:00485622740.020
proteasomal protein catabolic processGO:001049820.020
regulation of primary metabolic processGO:00800903110.020
stem cell maintenanceGO:001982740.020
cellular localizationGO:0051641970.020
Mouse Fly
protein metabolic processGO:00195381830.020
proteolysis involved in cellular protein catabolic processGO:005160330.020
negative regulation of protein transportGO:005122430.020
cellular component disassemblyGO:002241110.019
extrinsic apoptotic signaling pathwayGO:009719130.019
cell part morphogenesisGO:00329902460.019
nucleic acid templated transcriptionGO:00976591810.019
nucleobase containing compound metabolic processGO:00061392740.019
phosphatidylinositol mediated signalingGO:004801520.019
negative regulation of synapse assemblyGO:005196420.019
cellular amine metabolic processGO:004410620.019
atp catabolic processGO:000620040.018
carbohydrate biosynthetic processGO:001605110.018
neuron projection morphogenesisGO:00488121610.018
rna biosynthetic processGO:00327741810.018
regulation of tube sizeGO:003515020.018
positive regulation of cellular amine metabolic processGO:003324000.018
small molecule metabolic processGO:0044281770.018
nucleic acid transportGO:005065720.018
regulation of cell communicationGO:00106462320.018
heterocycle biosynthetic processGO:00181302150.018
single organism nuclear importGO:190259330.018
negative regulation of macromolecule metabolic processGO:0010605760.018
regulation of reproductive processGO:200024140.018
protein complex disassemblyGO:004324110.018
skeletal system developmentGO:00015011810.018
regulation of nucleoside metabolic processGO:000911820.018
membrane fusionGO:006102520.018
stem cell differentiationGO:00488631170.018
protein polymerizationGO:005125840.018
negative regulation of protein phosphorylationGO:000193340.018
negative regulation of sequestering of calcium ionGO:005128340.018
Mouse Fly
regulation of gene expressionGO:00104682650.018
regulation of nucleotide catabolic processGO:003081120.018
determination of bilateral symmetryGO:00098552040.018
ubiquitin dependent protein catabolic processGO:000651130.017
regulation of macromolecule metabolic processGO:00602553170.017
urogenital system developmentGO:0001655970.017
positive regulation of protein complex assemblyGO:003133420.017
cell cycle g1 s phase transitionGO:004484310.017
signal transduction in absence of ligandGO:003803410.017
chordate embryonic developmentGO:00430092710.017
brain developmentGO:00074202930.017
Fly
modification dependent protein catabolic processGO:001994130.017
regulation of cellular amino acid metabolic processGO:000652100.017
protein localization to plasma membraneGO:007265910.017
rna localizationGO:000640340.017
g protein coupled receptor signaling pathwayGO:0007186740.017
Fly
cellular amino acid metabolic processGO:000652070.017
regulation of autophagyGO:001050630.017
cellular protein catabolic processGO:004425740.017
regulation of cell deathGO:00109411030.017
convergent extensionGO:00600261180.017
inositol lipid mediated signalingGO:004801720.017
small molecule catabolic processGO:004428230.017
primary neural tube formationGO:001402010.017
regulation of bindingGO:005109830.017
actin filament polymerizationGO:003004120.017
cellular response to extracellular stimulusGO:003166820.017
locomotor rhythmGO:004547530.017
g1 s transition of mitotic cell cycleGO:000008210.016
multi organism processGO:00517041340.016
organic substance biosynthetic processGO:19015762890.016
macromolecule modificationGO:00434121110.016
positive regulation of cellular catabolic processGO:003133130.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
inorganic ion transmembrane transportGO:0098660570.016
Mouse Fly
gene expressionGO:00104672520.016
protein import into nucleusGO:000660630.016
macromolecular complex disassemblyGO:003298410.016
growthGO:00400071740.016
regulation of protein localization to nucleusGO:190018020.016
regulation of protein targetingGO:190353320.016
i kappab kinase nf kappab signalingGO:000724940.016
regulation of response to stimulusGO:00485832690.016
Fly
regulation of i kappab kinase nf kappab signalingGO:004312240.016
sensory organ developmentGO:00074233930.016
regulation of circadian rhythmGO:004275240.016
cellular component assemblyGO:00226071700.016
protein modification processGO:00362111000.016
cell cycle arrestGO:000705010.015
biosynthetic processGO:00090582940.015
cellular carbohydrate metabolic processGO:004426240.015
single organism metabolic processGO:00447102170.015
peptidyl lysine acetylationGO:001839420.015
chemosensory behaviorGO:000763510.015
cell morphogenesis involved in differentiationGO:00009041950.015
neurotransmitter transportGO:000683620.015
regulation of protein complex assemblyGO:004325430.015
cellular protein metabolic processGO:00442671290.015
angiogenesisGO:00015251580.015
nuclear importGO:005117030.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
neuron neuron synaptic transmissionGO:000727010.015
regulation of synaptic plasticityGO:004816710.015
developmental programmed cell deathGO:001062340.015
cellular response to hypoxiaGO:007145610.015
inorganic cation transmembrane transportGO:0098662500.015
Mouse Fly
single organism localizationGO:19025782250.015
Mouse Fly
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.015
golgi vesicle transportGO:004819330.015
regulation of cellular metabolic processGO:00313233200.014
tube closureGO:006060610.014
negative regulation of catabolic processGO:000989530.014
protein acetylationGO:000647320.014
cellular response to nutrient levelsGO:003166920.014
negative regulation of kinase activityGO:003367340.014
epithelial tube morphogenesisGO:00605621480.014
regulation of cellular biosynthetic processGO:00313262450.014
negative regulation of cytokine productionGO:000181810.014
exocytosisGO:000688710.014
cellular response to decreased oxygen levelsGO:003629410.014
negative regulation of defense responseGO:003134820.014
transcription dna templatedGO:00063511810.014
neuron projection guidanceGO:0097485860.014
phosphorus metabolic processGO:00067931090.014
negative regulation of protein kinase activityGO:000646940.014
regulation of endothelial cell proliferationGO:000193610.014
negative regulation of secretion by cellGO:190353120.014
programmed cell deathGO:00125011190.014
Mouse
regionalizationGO:00030022740.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
positive regulation of glucose importGO:004632610.014
endosomal transportGO:001619720.014
regulation of gtpase activityGO:004308720.014
regulation of purine nucleotide catabolic processGO:003312120.014
cellular nitrogen compound metabolic processGO:00346412900.014
organic cyclic compound biosynthetic processGO:19013622230.014
stem cell proliferationGO:007208940.014
compound eye developmentGO:004874920.014
muscle structure developmentGO:00610611960.014
lipid metabolic processGO:0006629520.013
calcium ion transport into cytosolGO:006040230.013
Mouse Fly
cellular biosynthetic processGO:00442492860.013
ovulation cycle processGO:002260220.013
apoptotic process involved in developmentGO:190274220.013
multicellular organismal signalingGO:0035637220.013
regulation of nucleocytoplasmic transportGO:004682220.013
positive regulation of lipase activityGO:006019310.013
response to endogenous stimulusGO:0009719830.013
cytoplasm organizationGO:000702840.013
mitochondrion organizationGO:000700540.013
cellular response to xenobiotic stimulusGO:0071466350.013
deathGO:00162651210.013
Mouse
positive regulation of glucose transportGO:001082810.013
regulation of blood pressureGO:000821710.013
cellular protein modification processGO:00064641000.013
regulation of blood vessel sizeGO:005088020.013
heterocycle metabolic processGO:00464832900.013
ameboidal type cell migrationGO:00016671430.013
cell matrix adhesionGO:000716040.013
periodic partitioningGO:000736510.013
regulation of metabolic processGO:00192223590.013
regulation of localizationGO:00328791040.013
Mouse Fly
sensory perception of painGO:001923310.013
secondary metabolic processGO:001974830.013
release of sequestered calcium ion into cytosolGO:005120930.013
Mouse Fly
rna 3 end processingGO:003112320.013
negative regulation of protein import into nucleusGO:004230820.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
negative regulation of protein localization to nucleusGO:190018120.012
neuroblast proliferationGO:000740520.012
negative regulation of cytoplasmic transportGO:190365020.012
eye developmentGO:00016542770.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
positive regulation of catabolic processGO:000989640.012
cellular response to hormone stimulusGO:0032870390.012
regulation of carbohydrate metabolic processGO:000610940.012
peptide transportGO:001583310.012
protein acylationGO:004354330.012
single organism transportGO:00447652060.012
Mouse Fly
toll like receptor signaling pathwayGO:000222440.012
regulation of anatomical structure morphogenesisGO:00226031300.012
protein importGO:001703830.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
regulation of phGO:000688530.012
rna metabolic processGO:00160702190.012
nucleic acid metabolic processGO:00903042440.012
renal system developmentGO:0072001940.012
cytokinesisGO:000091030.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
epithelial cell differentiationGO:00308551160.012
synaptic vesicle localizationGO:009747910.012
cellular transition metal ion homeostasisGO:004691630.012
regulation of systemic arterial blood pressureGO:000307310.012
regulation of protein catabolic processGO:004217610.012
single organism biosynthetic processGO:0044711710.012
positive regulation of nucleotide catabolic processGO:003081310.012
regulation of erk1 and erk2 cascadeGO:007037240.012
cytosolic calcium ion transportGO:006040130.012
Mouse Fly
negative regulation of nitrogen compound metabolic processGO:0051172590.012
lipid catabolic processGO:001604240.012
regulation of dna replicationGO:000627530.012
nitrogen compound metabolic processGO:00068073190.012
anterior posterior pattern specificationGO:00099521520.012
energy reserve metabolic processGO:000611220.012
nucleobase containing compound transportGO:001593120.012
protein phosphorylationGO:0006468470.012
regulation of filopodium assemblyGO:005148920.012
cellular response to organic substanceGO:00713101050.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
sequestering of calcium ionGO:005120830.012
Mouse Fly
negative regulation of response to stimulusGO:00485851040.012
regulation of biosynthetic processGO:00098892500.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
organelle localizationGO:0051640490.012
striated muscle cell developmentGO:00550021080.011
regulation of stem cell differentiationGO:200073640.011
muscle cell migrationGO:001481240.011
behaviorGO:0007610740.011
Fly
cellular response to oxygen levelsGO:007145310.011
germ line stem cell maintenanceGO:003071820.011
cellular response to starvationGO:000926710.011
centrosome organizationGO:005129710.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
maternal determination of anterior posterior axis embryoGO:000835840.011
regulation of multicellular organismal developmentGO:20000262230.011
neural crest cell differentiationGO:0014033720.011
muscle tissue developmentGO:00605371100.011
phagocytosis engulfmentGO:000691110.011
leukocyte proliferationGO:007066110.011
negative regulation of reproductive processGO:200024230.011
triglyceride homeostasisGO:007032820.011
sequestering of metal ionGO:005123830.011
Mouse Fly
post golgi vesicle mediated transportGO:000689210.011
stem cell divisionGO:001714510.011
regulation of chromosome segregationGO:005198310.011
monovalent inorganic cation transportGO:0015672420.011
organelle organizationGO:00069962270.011
Fly
response to xenobiotic stimulusGO:0009410450.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
single organism organelle organizationGO:19025891990.011
cellular lipid catabolic processGO:004424230.011
intracellular mrna localizationGO:000829810.011
negative regulation of small gtpase mediated signal transductionGO:005105810.011
vacuolar transportGO:000703420.011
regulation of protein polymerizationGO:003227120.011
cortical cytoskeleton organizationGO:003086510.011
positive regulation of stress activated mapk cascadeGO:003287430.011
nucleobase containing compound biosynthetic processGO:00346542050.011
positive regulation of lipid metabolic processGO:004583410.011
regulation of fatty acid metabolic processGO:001921710.011
peptidyl tyrosine dephosphorylationGO:003533510.011
chemical homeostasisGO:0048878490.011
Mouse Fly
peptidyl serine modificationGO:001820920.011
regulation of intracellular protein transportGO:003315730.011
alcohol biosynthetic processGO:004616520.011
smooth muscle contractionGO:000693920.011
regulation of dendrite morphogenesisGO:004881430.011
meiotic cell cycle processGO:190304630.011
positive regulation of cell divisionGO:005178120.011
cellular response to biotic stimulusGO:007121630.011
negative regulation of cell deathGO:0060548600.011
embryonic heart tube morphogenesisGO:00031431080.011
glucose homeostasisGO:004259310.011
rhythmic processGO:0048511210.010
regulation of programmed cell deathGO:00430671010.010
spermatid developmentGO:000728620.010
membrane invaginationGO:001032410.010
positive regulation of nucleoside metabolic processGO:004597910.010
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.010
synaptic vesicle transportGO:004848910.010
microtubule organizing center organizationGO:003102310.010
regulation of cellular component movementGO:0051270550.010
wound healingGO:0042060900.010
positive regulation of exocytosisGO:004592110.010
macroautophagyGO:001623610.010
neural crest cell migrationGO:0001755420.010
cellular aromatic compound metabolic processGO:00067252950.010
glycerolipid biosynthetic processGO:004501710.010
carbohydrate homeostasisGO:003350010.010
negative regulation of intracellular transportGO:003238730.010
negative regulation of dna metabolic processGO:005105340.010
positive regulation of synapse assemblyGO:005196510.010
cell deathGO:00082191210.010
Mouse
carboxylic acid catabolic processGO:004639530.010

itpr1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.022
disease of anatomical entityDOID:700.020
cardiovascular system diseaseDOID:128700.020
nervous system diseaseDOID:86300.018
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.014
eye and adnexa diseaseDOID:149200.012
sensory system diseaseDOID:005015500.012
inherited metabolic disorderDOID:65500.011
organ system cancerDOID:005068600.011
musculoskeletal system diseaseDOID:1700.011
myopathyDOID:42300.011
muscle tissue diseaseDOID:6600.011
muscular diseaseDOID:008000000.011
eye diseaseDOID:561400.011