Danio rerio

0 known processes

penka

proenkephalin a

(Aliases: penkl,zgc:73353)

penka biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular nitrogen compound biosynthetic processGO:00442712180.258
regulation of nucleobase containing compound metabolic processGO:00192192500.251
cellular aromatic compound metabolic processGO:00067252950.246
cell surface receptor signaling pathwayGO:00071663250.232
nucleobase containing compound biosynthetic processGO:00346542050.198
aromatic compound biosynthetic processGO:00194382170.191
regulation of nitrogen compound metabolic processGO:00511712510.183
organic cyclic compound biosynthetic processGO:19013622230.181
regulation of cellular metabolic processGO:00313233200.180
regulation of catalytic activityGO:0050790550.176
organic substance biosynthetic processGO:19015762890.168
organic cyclic compound metabolic processGO:19013603010.163
regulation of ion transmembrane transporter activityGO:003241220.157
gene expressionGO:00104672520.153
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:000718750.151
biosynthetic processGO:00090582940.141
rna biosynthetic processGO:00327741810.130
nucleobase containing compound metabolic processGO:00061392740.129
nitrogen compound metabolic processGO:00068073190.125
cellular nitrogen compound metabolic processGO:00346412900.124
adult behaviorGO:003053420.122
regulation of metabolic processGO:00192223590.118
cognitionGO:005089010.117
cellular component morphogenesisGO:00329893360.112
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:000718850.111
nucleic acid metabolic processGO:00903042440.110
heterocycle metabolic processGO:00464832900.109
cell projection organizationGO:00300302840.108
cellular macromolecule metabolic processGO:00442603910.106
negative regulation of biological processGO:00485193040.104
signal transductionGO:00071654550.103
rna metabolic processGO:00160702190.103
regulation of biosynthetic processGO:00098892500.100
regulation of cellular biosynthetic processGO:00313262450.099
cellular protein metabolic processGO:00442671290.096
cellular amine metabolic processGO:004410620.092
heterocycle biosynthetic processGO:00181302150.089
positive regulation of transportGO:005105020.089
localization of cellGO:00516742440.087
glutamate receptor signaling pathwayGO:000721510.086
larval developmentGO:000216420.083
regulation of macromolecule metabolic processGO:00602553170.081
g protein coupled receptor signaling pathwayGO:0007186740.080
regulation of transporter activityGO:003240920.079
dopamine metabolic processGO:004241720.076
regulation of primary metabolic processGO:00800903110.074
regulation of transmembrane transporter activityGO:002289820.072
amine metabolic processGO:000930820.071
positive regulation of cellular processGO:00485222010.071
regulation of reproductive processGO:200024140.067
regulation of gene expressionGO:00104682650.066
transcription from rna polymerase ii promoterGO:0006366800.066
regulation of response to stimulusGO:00485832690.065
establishment of localizationGO:00512342440.065
positive regulation of camp metabolic processGO:003081620.064
cellular macromolecule biosynthetic processGO:00346452240.063
regulation of localizationGO:00328791040.063
response to amineGO:001407510.062
catechol containing compound metabolic processGO:000971220.061
sensory organ developmentGO:00074233930.061
nucleoside phosphate biosynthetic processGO:1901293210.060
ion transportGO:00068111140.059
organonitrogen compound biosynthetic processGO:1901566470.059
organonitrogen compound metabolic processGO:1901564740.057
neuron projection morphogenesisGO:00488121610.057
negative regulation of cellular processGO:00485232830.056
regulation of cytoplasmic transportGO:190364940.056
response to chemicalGO:00422213200.056
locomotionGO:00400113130.055
regulation of phosphate metabolic processGO:0019220430.054
negative regulation of molecular functionGO:0044092230.054
regulation of transmembrane transportGO:0034762180.053
neuron neuron synaptic transmissionGO:000727010.053
regulation of signalingGO:00230512350.053
nucleic acid templated transcriptionGO:00976591810.052
regulation of transcription dna templatedGO:00063552130.052
regulation of calcium ion transportGO:005192420.050
regulation of ion transportGO:0043269220.050
single organism localizationGO:19025782250.049
macromolecule modificationGO:00434121110.049
nucleotide biosynthetic processGO:0009165210.048
regulation of multicellular organismal processGO:00512392770.048
regulation of cellular amine metabolic processGO:003323800.047
cell part morphogenesisGO:00329902460.047
regulation of macromolecule biosynthetic processGO:00105562250.046
cyclic nucleotide biosynthetic processGO:0009190180.046
negative regulation of metabolic processGO:0009892860.046
regulation of cellular macromolecule biosynthetic processGO:20001122220.045
positive regulation of biological processGO:00485182530.045
regulation of lyase activityGO:0051339120.044
positive regulation of metabolic processGO:00098931080.044
response to amphetamineGO:000197510.044
eye developmentGO:00016542770.043
regulation of rna metabolic processGO:00512522240.043
inner ear developmentGO:00488391260.042
cellular biosynthetic processGO:00442492860.042
regulation of signal transductionGO:00099662250.041
generation of neuronsGO:00486993850.041
protein modification processGO:00362111000.041
response to organic substanceGO:00100331530.041
neuron projection developmentGO:00311751800.040
macromolecule biosynthetic processGO:00090592270.040
single organism transportGO:00447652060.039
dopaminergic neuron differentiationGO:0071542140.039
regulation of rna biosynthetic processGO:20011412130.039
purine ribonucleotide biosynthetic processGO:0009152200.039
response to endogenous stimulusGO:0009719830.039
catecholamine metabolic processGO:000658420.039
regulation of dendrite developmentGO:005077330.039
mechanosensory lateral line system developmentGO:0048881490.038
regulation of cyclase activityGO:0031279120.038
regulation of protein transportGO:005122330.038
regulation of cell communicationGO:00106462320.038
response to abiotic stimulusGO:00096281220.038
locomotory behaviorGO:0007626340.038
Mouse
regulation of receptor activityGO:001046920.037
regulation of protein localization to nucleusGO:190018020.036
phagocytosisGO:000690930.036
regulation of intracellular protein transportGO:003315730.036
regulation of ion transmembrane transportGO:0034765180.035
regulation of nucleocytoplasmic transportGO:004682220.035
regulation of transportGO:0051049450.035
cell projection morphogenesisGO:00488582440.034
establishment of protein localization to organelleGO:007259440.034
regulation of establishment of protein localizationGO:007020140.034
positive regulation of gene expressionGO:0010628710.033
regulation of nucleotide biosynthetic processGO:0030808150.033
nucleocytoplasmic transportGO:000691340.033
metal ion transportGO:0030001580.033
regulation of developmental processGO:00507932470.033
regulation of nucleic acid templated transcriptionGO:19035062130.033
cell morphogenesisGO:00009022890.032
regulation of locomotionGO:0040012550.032
sensory system developmentGO:0048880760.032
protein targeting to nucleusGO:004474430.032
nuclear transportGO:005116940.032
regulation of metal ion transportGO:001095940.031
chemotaxisGO:00069351040.031
positive regulation of cellular metabolic processGO:0031325940.031
nuclear importGO:005117030.031
regulation of cyclic nucleotide biosynthetic processGO:0030802150.031
regulation of nucleotide metabolic processGO:0006140170.031
purine nucleotide biosynthetic processGO:0006164200.030
ear developmentGO:00435831270.030
regulation of adenylate cyclase activityGO:004576160.030
neuron differentiationGO:00301823530.030
negative regulation of catabolic processGO:000989530.030
regionalizationGO:00030022740.030
regulation of cellular amino acid metabolic processGO:000652100.030
regulation of protein import into nucleusGO:004230620.030
response to light stimulusGO:0009416460.030
cation transportGO:0006812810.030
transportGO:00068102200.030
purine containing compound biosynthetic processGO:0072522200.030
directional locomotionGO:003305810.030
positive regulation of nitrogen compound metabolic processGO:0051173690.029
camp metabolic processGO:0046058110.029
regulation of molecular functionGO:0065009700.029
organelle organizationGO:00069962270.029
phosphorus metabolic processGO:00067931090.029
positive regulation of camp biosynthetic processGO:003081920.029
lateral line system developmentGO:0048925760.028
single organism nuclear importGO:190259330.028
ribonucleotide biosynthetic processGO:0009260200.028
multicellular organism growthGO:003526440.028
cell differentiation in spinal cordGO:0021515400.028
cellular ketone metabolic processGO:0042180110.028
regulation of cellular ketone metabolic processGO:001056570.028
regulation of neurogenesisGO:0050767870.028
chemosensory behaviorGO:000763510.027
regulation of camp biosynthetic processGO:003081790.027
cell morphogenesis involved in neuron differentiationGO:00486671630.027
regulation of extrinsic apoptotic signaling pathwayGO:200123630.027
regulation of multicellular organismal developmentGO:20000262230.026
positive regulation of cellular component biogenesisGO:004408930.026
neurological system processGO:0050877620.026
Mouse
cellular amino acid metabolic processGO:000652070.026
gastrulationGO:00073692080.026
positive regulation of biosynthetic processGO:0009891680.026
protein localization to nucleusGO:003450430.026
camp biosynthetic processGO:0006171110.026
morphogenesis of an epitheliumGO:00020093330.025
cell migrationGO:00164772370.025
neuron developmentGO:00486662620.025
positive regulation of cellular amine metabolic processGO:003324000.025
regulation of cyclic nucleotide metabolic processGO:0030799150.025
cellular component biogenesisGO:00440851780.025
embryonic organ developmentGO:00485683810.025
cellular component movementGO:00069283350.025
catechol containing compound biosynthetic processGO:000971320.025
agingGO:000756820.024
peptidyl serine modificationGO:001820920.024
negative regulation of protein kinase activityGO:000646940.024
carboxylic acid metabolic processGO:0019752220.024
transmembrane transportGO:00550851200.024
hormone secretionGO:004687920.024
transcription dna templatedGO:00063511810.024
central nervous system neuron axonogenesisGO:0021955180.024
lateral line developmentGO:0048882660.024
negative regulation of protein phosphorylationGO:000193340.024
behaviorGO:0007610740.024
Mouse
diencephalon developmentGO:0021536580.024
cell motilityGO:00488702440.024
protein importGO:001703830.024
protein import into nucleusGO:000660630.023
regulation of cell developmentGO:00602841000.023
retina development in camera type eyeGO:00600411460.023
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.023
regulation of synapse organizationGO:005080730.023
positive regulation of nucleobase containing compound metabolic processGO:0045935690.023
head developmentGO:00603223030.022
cell morphogenesis involved in differentiationGO:00009041950.022
sleepGO:003043110.022
single organism metabolic processGO:00447102170.022
mitochondrion organizationGO:000700540.022
central nervous system developmentGO:00074173870.022
regulation of purine nucleotide biosynthetic processGO:1900371150.022
ribose phosphate biosynthetic processGO:0046390200.022
phosphate containing compound metabolic processGO:00067961080.022
endocrine system developmentGO:0035270650.021
posterior lateral line system developmentGO:0048915460.021
regulation of peptidyl tyrosine phosphorylationGO:005073010.021
positive regulation of catabolic processGO:000989640.021
developmental maturationGO:0021700340.021
regulation of cell deathGO:00109411030.021
positive regulation of signalingGO:0023056560.021
response to glucoseGO:000974930.021
regulation of phosphorus metabolic processGO:0051174430.020
tube morphogenesisGO:00352393490.020
neuroblast proliferationGO:000740520.020
central nervous system neuron differentiationGO:0021953740.020
oxoacid metabolic processGO:0043436310.020
organic acid metabolic processGO:0006082310.020
single organism biosynthetic processGO:0044711710.020
neuron projection extensionGO:1990138450.020
regulation of cell differentiationGO:00455951420.020
proteolysis involved in cellular protein catabolic processGO:005160330.020
catecholamine biosynthetic processGO:004242320.020
hormone transportGO:000991420.019
regulation of anatomical structure morphogenesisGO:00226031300.019
carbohydrate derivative biosynthetic processGO:1901137430.019
negative regulation of protein transportGO:005122430.019
calcium ion transportGO:0006816180.019
positive regulation of macromolecule metabolic processGO:0010604930.019
central nervous system neuron developmentGO:0021954290.019
cellular amide metabolic processGO:004360340.019
carbohydrate homeostasisGO:003350010.019
compound eye developmentGO:004874920.019
positive regulation of cell communicationGO:0010647560.019
negative regulation of catalytic activityGO:0043086210.019
maintenance of locationGO:005123540.018
cellular response to radiationGO:007147840.018
dorsal ventral pattern formationGO:00099531250.018
anterior posterior pattern specificationGO:00099521520.018
multicellular organismal response to stressGO:003355520.018
Mouse
response to carbohydrateGO:000974330.018
proteasomal protein catabolic processGO:001049820.018
regulation of hormone secretionGO:004688320.018
negative regulation of gene expressionGO:0010629650.018
positive regulation of nucleic acid templated transcriptionGO:1903508570.018
cellular localizationGO:0051641970.018
cellular protein modification processGO:00064641000.018
brain developmentGO:00074202930.018
positive regulation of rna metabolic processGO:0051254590.018
regulation of cell morphogenesis involved in differentiationGO:0010769380.018
camera type eye developmentGO:00430102220.017
guanosine containing compound catabolic processGO:190106920.017
cellular component assemblyGO:00226071700.017
positive regulation of cell cycleGO:004578730.017
modification dependent macromolecule catabolic processGO:004363230.017
cellular response to light stimulusGO:007148240.017
regulation of purine nucleotide metabolic processGO:1900542170.017
alpha amino acid metabolic processGO:190160530.017
calcium ion transmembrane transportGO:0070588130.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
cellular protein catabolic processGO:004425740.017
regulation of oligodendrocyte differentiationGO:004871310.017
negative regulation of macromolecule metabolic processGO:0010605760.017
ion transmembrane transportGO:0034220910.017
muscle structure developmentGO:00610611960.017
establishment of synaptic vesicle localizationGO:009748010.016
single organism behaviorGO:0044708240.016
Mouse
neuromuscular process controlling balanceGO:005088530.016
cellular component disassemblyGO:002241110.016
response to ketoneGO:190165410.016
ubiquitin dependent protein catabolic processGO:000651130.016
response to hexoseGO:000974630.016
negative regulation of cellular metabolic processGO:0031324770.016
peptide transportGO:001583310.016
positive regulation of molecular functionGO:0044093330.016
protein metabolic processGO:00195381830.016
positive regulation of purine nucleotide biosynthetic processGO:190037380.016
regulation of jak stat cascadeGO:004642530.016
gtp metabolic processGO:004603940.016
negative regulation of kinase activityGO:003367340.015
intracellular signal transductionGO:0035556850.015
macromolecular complex disassemblyGO:003298410.015
single organism cellular localizationGO:1902580460.015
negative regulation of gliogenesisGO:001401410.015
divalent inorganic cation transportGO:0072511210.015
regulation of transcription from rna polymerase ii promoterGO:00063571140.015
taxisGO:00423301090.015
axon developmentGO:00615641660.015
negative regulation of sequestering of calcium ionGO:005128340.015
positive regulation of secretionGO:005104710.015
regulation of dendrite morphogenesisGO:004881430.015
axon extensionGO:0048675450.015
maternal determination of anterior posterior axis embryoGO:000835840.015
regulation of synapse assemblyGO:005196330.015
spinal cord motor neuron differentiationGO:0021522260.015
interspecies interaction between organismsGO:004441940.015
phosphorylationGO:0016310690.015
regulation of bindingGO:005109830.015
negative regulation of cell communicationGO:0010648960.015
membrane invaginationGO:001032410.015
monoamine transportGO:001584410.015
negative regulation of nucleocytoplasmic transportGO:004682320.015
regulation of synaptic plasticityGO:004816710.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
positive regulation of map kinase activityGO:004340630.014
regulation of membrane potentialGO:0042391230.014
renal system developmentGO:0072001940.014
synaptic growth at neuromuscular junctionGO:005112420.014
establishment of localization in cellGO:0051649770.014
response to external stimulusGO:00096052640.014
Mouse
regulation of multicellular organism growthGO:004001440.014
regulation of biological qualityGO:00650082630.014
small molecule catabolic processGO:004428230.014
positive regulation of response to stimulusGO:0048584800.014
positive regulation of cellular catabolic processGO:003133130.014
cellular response to extracellular stimulusGO:003166820.014
meiotic nuclear divisionGO:000712640.014
gland developmentGO:00487321430.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
regulation of glial cell differentiationGO:004568540.014
developmental cell growthGO:0048588520.014
organophosphate metabolic processGO:0019637370.014
regulation of protein targetingGO:190353320.014
neuron migrationGO:0001764220.014
regulation of cytokine productionGO:000181730.014
developmental growthGO:00485891660.014
modification dependent protein catabolic processGO:001994130.013
regulation of protein catabolic processGO:004217610.013
regulation of cell shapeGO:000836010.013
homeostatic processGO:00425921420.013
peptidyl serine phosphorylationGO:001810510.013
response to hormoneGO:0009725480.013
positive regulation of rna biosynthetic processGO:1902680570.013
small molecule metabolic processGO:0044281770.013
organophosphate biosynthetic processGO:0090407230.013
membrane hyperpolarizationGO:006008110.013
gabaergic neuron differentiationGO:009715420.013
regulation of nervous system developmentGO:0051960900.013
response to foodGO:003209410.013
heart developmentGO:00075073130.013
water homeostasisGO:003010440.013
development of primary female sexual characteristicsGO:004654540.013
protein phosphorylationGO:0006468470.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
regulation of circadian rhythmGO:004275240.012
positive regulation of secretion by cellGO:190353210.012
regulation of purine nucleotide catabolic processGO:003312120.012
autophagyGO:000691440.012
sequestering of metal ionGO:005123830.012
positive regulation of transcription dna templatedGO:0045893570.012
protein stabilizationGO:005082120.012
regulation of neuron differentiationGO:0045664560.012
cyclic nucleotide metabolic processGO:0009187180.012
digestive system developmentGO:00551232890.012
axonogenesisGO:00074091520.012
sensory perception of chemical stimulusGO:000760630.012
stem cell proliferationGO:007208940.012
system processGO:00030081850.012
Mouse
liver developmentGO:0001889960.012
regulation of neuron projection developmentGO:0010975400.012
negative regulation of reproductive processGO:200024230.012
mesenchymal cell differentiationGO:0048762870.012
convergent extensionGO:00600261180.012
regulation of sequestering of calcium ionGO:005128240.012
regulation of inflammatory responseGO:005072720.011
growthGO:00400071740.011
guanosine containing compound metabolic processGO:190106840.011
photoreceptor cell developmentGO:0042461400.011
regulation of mrna splicing via spliceosomeGO:004802430.011
chordate embryonic developmentGO:00430092710.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
cellular response to chemical stimulusGO:00708871570.011
cellular response to endogenous stimulusGO:0071495680.011
deathGO:00162651210.011
divalent metal ion transportGO:0070838200.011
synaptic transmissionGO:0007268350.011
skeletal system developmentGO:00015011810.011
cellular response to external stimulusGO:007149620.011
cation transmembrane transportGO:0098655650.011
positive regulation of cytoskeleton organizationGO:005149530.011
positive regulation of nucleotide biosynthetic processGO:003081080.011
response to monosaccharideGO:003428430.011
spinal cord developmentGO:0021510460.011
multi organism cellular processGO:004476420.011
regulation of programmed cell deathGO:00430671010.011
antimicrobial humoral responseGO:001973020.011
regulation of erk1 and erk2 cascadeGO:007037240.011
positive regulation of lyase activityGO:005134960.011
positive regulation of nucleoside metabolic processGO:004597910.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.010
axon guidanceGO:0007411860.010
positive regulation of cyclase activityGO:003128160.010
embryonic organ morphogenesisGO:00485622740.010
neurotransmitter secretionGO:000726920.010
regulation of cellular component organizationGO:0051128860.010
inorganic ion transmembrane transportGO:0098660570.010
phenol containing compound biosynthetic processGO:004618940.010
extrinsic apoptotic signaling pathwayGO:009719130.010
sequestering of calcium ionGO:005120830.010
response to alkaloidGO:004327920.010
neurotransmitter transportGO:000683620.010
regulation of cell substrate adhesionGO:001081010.010
synaptic vesicle localizationGO:009747910.010
phenol containing compound metabolic processGO:001895850.010

penka disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.031
nervous system diseaseDOID:86300.017
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
disease of metabolismDOID:001466700.011