Danio rerio

69 known processes

f2r

coagulation factor II (thrombin) receptor

(Aliases: si:ch211-130m23.4,par1)

f2r biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
hemopoiesisGO:00300971830.831
primitive erythrocyte differentiationGO:006031950.747
immune system developmentGO:00025201910.512
myeloid cell differentiationGO:0030099860.489
hematopoietic or lymphoid organ developmentGO:00485341910.461
myeloid leukocyte differentiationGO:0002573150.459
convergent extensionGO:00600261180.376
convergent extension involved in gastrulationGO:0060027710.361
embryonic hemopoiesisGO:0035162530.357
digestive tract morphogenesisGO:00485462310.326
sensory organ developmentGO:00074233930.321
vasculature developmentGO:00019442780.289
rna metabolic processGO:00160702190.269
Human
negative regulation of blood circulationGO:190352320.266
Mouse
regulation of blood circulationGO:1903522320.261
Mouse Rat
erythrocyte differentiationGO:0030218540.257
cellular response to nutrient levelsGO:003166920.213
positive regulation of cellular component biogenesisGO:004408930.212
erythrocyte homeostasisGO:0034101550.169
positive regulation of epithelial cell proliferationGO:005067910.162
cellular nitrogen compound biosynthetic processGO:00442712180.162
Human
gastrulationGO:00073692080.161
primitive hemopoiesisGO:0060215270.159
embryonic organ developmentGO:00485683810.156
myeloid cell homeostasisGO:0002262560.151
eye developmentGO:00016542770.147
rna biosynthetic processGO:00327741810.146
Human
regulation of gene expressionGO:00104682650.123
Human
leukocyte differentiationGO:0002521250.120
heterocycle biosynthetic processGO:00181302150.119
Human
taxisGO:00423301090.119
nucleic acid templated transcriptionGO:00976591810.115
Human
regulation of transcription dna templatedGO:00063552130.110
Human
regulation of cellular metabolic processGO:00313233200.109
Human Mouse Rat
digestive system developmentGO:00551232890.108
tube morphogenesisGO:00352393490.105
morphogenesis of an epitheliumGO:00020093330.103
regulation of calcium dependent cell cell adhesionGO:004658610.102
cellular macromolecule biosynthetic processGO:00346452240.100
Human
regulation of immune system processGO:0002682340.099
single organism cell adhesionGO:0098602290.097
specification of symmetryGO:00097992040.096
regulation of metabolic processGO:00192223590.093
Human Mouse Rat
cell part morphogenesisGO:00329902460.092
transcription from rna polymerase ii promoterGO:0006366800.089
regulation of cell adhesionGO:0030155150.089
nephron epithelium morphogenesisGO:007208810.089
regulation of macromolecule biosynthetic processGO:00105562250.088
Human
neuron differentiationGO:00301823530.087
renal filtrationGO:0097205100.084
Rat
blood vessel developmentGO:00015682460.082
digestive tract developmentGO:00485652650.080
central nervous system formationGO:002155610.080
negative regulation of cell cell adhesionGO:002240860.079
regulation of cellular biosynthetic processGO:00313262450.077
Human
positive regulation of map kinase activityGO:004340630.077
Rat
synaptic target recognitionGO:000803910.076
tissue remodelingGO:004877140.075
Human
lateral inhibitionGO:004633110.073
embryonic organ morphogenesisGO:00485622740.071
heart morphogenesisGO:00030071560.071
immune system processGO:00023762410.070
gene expressionGO:00104672520.070
Human
establishment of endothelial barrierGO:006102830.070
fin developmentGO:0033333770.070
heart joggingGO:0003146400.070
cell migrationGO:00164772370.070
Human Mouse
regulation of autophagyGO:001050630.069
larval developmentGO:000216420.068
mesenchymal cell proliferationGO:001046310.068
amine metabolic processGO:000930820.067
cell projection organizationGO:00300302840.066
determination of heart left right asymmetryGO:00613711170.064
b cell activationGO:004211320.064
embryonic heart tube morphogenesisGO:00031431080.062
generation of neuronsGO:00486993850.062
regulation of systemic arterial blood pressureGO:000307310.061
Mouse Rat
nucleobase containing compound biosynthetic processGO:00346542050.060
Human
angiogenesisGO:00015251580.058
negative regulation of stem cell differentiationGO:200073720.058
cellular response to chemical stimulusGO:00708871570.058
regulation of epithelial cell proliferationGO:005067830.057
system processGO:00030081850.056
Mouse Rat
response to external stimulusGO:00096052640.056
Human Mouse
epithelial cell morphogenesisGO:000338220.054
monocyte differentiationGO:003022420.053
definitive hemopoiesisGO:0060216180.053
regulation of localizationGO:00328791040.053
Human Mouse Rat
regulation of production of molecular mediator of immune responseGO:000270010.052
b cell differentiationGO:003018310.050
renal system processGO:0003014140.050
Mouse Rat
cellular response to external stimulusGO:007149620.049
nephron tubule morphogenesisGO:007207810.048
axonal defasciculationGO:000741420.048
regulation of cellular component movementGO:0051270550.047
Human Mouse
metal ion transportGO:0030001580.047
Human Rat
cellular carbohydrate metabolic processGO:004426240.046
homeostasis of number of cellsGO:0048872620.046
Mouse
cellular response to extracellular stimulusGO:003166820.046
regulation of multicellular organismal processGO:00512392770.045
cellular response to starvationGO:000926710.045
response to nitrogen compoundGO:1901698190.045
response to fluid shear stressGO:003440520.045
regulation of primary metabolic processGO:00800903110.045
Human Rat
glomerular filtrationGO:000309460.045
Rat
positive regulation of chromosome organizationGO:200125210.045
positive regulation of endothelial cell proliferationGO:000193810.045
response to chemicalGO:00422213200.044
Mouse
blood circulationGO:0008015870.044
Mouse Rat
energy reserve metabolic processGO:000611220.043
regulation of erythrocyte differentiationGO:004564620.043
endodermal cell fate determinationGO:000749320.043
regulation of nucleobase containing compound metabolic processGO:00192192500.042
Human
regulation of nucleic acid templated transcriptionGO:19035062130.042
Human
locomotor rhythmGO:004547530.042
endoderm developmentGO:0007492490.041
locomotionGO:00400113130.041
Human Mouse
regulation of embryonic developmentGO:0045995470.040
regulation of cytoskeleton organizationGO:0051493110.040
regulation of dna templated transcription in response to stressGO:004362000.040
determination of left right symmetryGO:00073681790.039
regulation of rna metabolic processGO:00512522240.038
Human
cell projection morphogenesisGO:00488582440.038
phosphate containing compound metabolic processGO:00067961080.038
Human Mouse Rat
regulation of cell shapeGO:000836010.038
heart loopingGO:0001947940.038
negative regulation of rna metabolic processGO:0051253480.038
cellular amine metabolic processGO:004410620.037
cellular component movementGO:00069283350.037
Human Mouse
organonitrogen compound biosynthetic processGO:1901566470.037
phosphorus metabolic processGO:00067931090.036
Human Mouse Rat
heart developmentGO:00075073130.035
renal system developmentGO:0072001940.035
chemotaxisGO:00069351040.035
aromatic compound biosynthetic processGO:00194382170.035
Human
positive regulation of signal transductionGO:0009967560.034
Human Mouse Rat
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.034
Human Rat
protein targeting to nucleusGO:004474430.034
Human
regulation of cell migrationGO:0030334400.034
Human Mouse
localization of cellGO:00516742440.034
Human Mouse
positive regulation of transcription dna templatedGO:0045893570.034
Human
leukocyte proliferationGO:007066110.034
protein secretionGO:000930610.033
Human Mouse
epithelial tube morphogenesisGO:00605621480.033
regulation of cell differentiationGO:00455951420.033
homeostatic processGO:00425921420.033
Human Mouse Rat
i kappab kinase nf kappab signalingGO:000724940.032
Human
dorsal convergenceGO:0060030140.032
circadian behaviorGO:004851250.031
regulation of endopeptidase activityGO:0052548230.031
Human
modification dependent protein catabolic processGO:001994130.031
regulation of tube sizeGO:003515020.031
Mouse Rat
biosynthetic processGO:00090582940.030
Human
positive regulation of stem cell proliferationGO:200064810.030
regulation of blood vessel sizeGO:005088020.030
Mouse Rat
regulation of heart growthGO:006042020.030
positive regulation of nitrogen compound metabolic processGO:0051173690.030
Human
intermediate mesoderm developmentGO:004838920.030
positive regulation of catabolic processGO:000989640.030
positive regulation of apoptotic processGO:0043065290.030
Human
single organism transportGO:00447652060.029
Human Mouse Rat
cation transportGO:0006812810.029
Human Rat
oxoacid metabolic processGO:0043436310.029
ribosomal small subunit biogenesisGO:004227420.029
regulation of cellular amino acid metabolic processGO:000652100.029
cellular nitrogen compound metabolic processGO:00346412900.028
Human
regulation of macromolecule metabolic processGO:00602553170.028
Human Rat
production of molecular mediator of immune responseGO:000244020.028
regulation of myeloid cell differentiationGO:004563780.028
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.028
positive regulation of cellular catabolic processGO:003133130.028
regulation of rna biosynthetic processGO:20011412130.028
Human
regulation of establishment of planar polarityGO:009017540.028
negative regulation of rna biosynthetic processGO:1902679450.028
positive regulation of locomotionGO:0040017140.027
Human Mouse
regulation of stem cell differentiationGO:200073640.027
positive regulation of leukocyte chemotaxisGO:000269010.027
telomere organizationGO:003220010.027
pyruvate metabolic processGO:000609010.027
cellular response to radiationGO:007147840.026
negative regulation of nitrogen compound metabolic processGO:0051172590.026
regulation of cellular protein catabolic processGO:190336210.026
regulation of protein bindingGO:004339330.026
positive regulation of cellular amino acid metabolic processGO:004576400.025
cellular response to drugGO:003569010.025
positive regulation of leukocyte migrationGO:000268720.025
female gonad developmentGO:000858540.025
cellular ketone metabolic processGO:0042180110.025
camera type eye developmentGO:00430102220.025
positive regulation of secretionGO:005104710.024
Human
extrinsic apoptotic signaling pathwayGO:009719130.024
regulation of organ growthGO:004662030.024
positive regulation of axon guidanceGO:190266910.024
embryonic heart tube developmentGO:00350501330.024
cell motilityGO:00488702440.024
Human Mouse
regulation of signal transductionGO:00099662250.024
Human Mouse Rat
cellular transition metal ion homeostasisGO:004691630.024
regulation of receptor mediated endocytosisGO:004825940.023
transportGO:00068102200.023
Human Mouse Rat
regulation of protein transportGO:005122330.023
Human Mouse
positive regulation of immune system processGO:0002684170.023
sensory organ morphogenesisGO:00905962000.023
organic cyclic compound biosynthetic processGO:19013622230.023
Human
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.023
cytokinesisGO:000091030.023
regulation of nitrogen compound metabolic processGO:00511712510.023
Human
response to abiotic stimulusGO:00096281220.023
nephron morphogenesisGO:007202820.023
organophosphate metabolic processGO:0019637370.022
endoderm formationGO:0001706290.022
positive regulation of proteolysisGO:0045862100.022
Human
modification dependent macromolecule catabolic processGO:004363230.022
regulation of locomotionGO:0040012550.022
Human Mouse
striated muscle tissue developmentGO:00147061100.022
organonitrogen compound metabolic processGO:1901564740.022
regulation of biological qualityGO:00650082630.022
Human Mouse Rat
heterocycle metabolic processGO:00464832900.022
Human
lymph vessel developmentGO:0001945270.022
regulation of neural precursor cell proliferationGO:200017730.021
macroautophagyGO:001623610.021
cell agingGO:000756920.021
ion transportGO:00068111140.021
Human Rat
regulation of epithelial to mesenchymal transitionGO:001071730.021
negative regulation of metabolic processGO:0009892860.021
central nervous system developmentGO:00074173870.021
neuron projection developmentGO:00311751800.021
septum transversum developmentGO:000334340.021
regulation of developmental processGO:00507932470.021
glomerulus vasculature developmentGO:007201220.021
negative regulation of sequestering of calcium ionGO:005128340.020
Human Rat
positive regulation of protein kinase b signalingGO:005189710.020
response to radiationGO:0009314510.020
sulfur compound transportGO:007234830.020
limbic system developmentGO:0021761160.020
renal tubule morphogenesisGO:006133310.020
regulation of mesenchymal cell proliferationGO:001046410.020
positive regulation of epithelial cell migrationGO:001063420.020
regulation of cellular ketone metabolic processGO:001056570.020
negative regulation of transcription dna templatedGO:0045892450.020
cell adhesionGO:0007155400.020
signal transductionGO:00071654550.020
positive regulation of stress activated mapk cascadeGO:003287430.020
positive regulation of cellular processGO:00485222010.020
Human Mouse Rat
nitrogen compound metabolic processGO:00068073190.020
Human
protein dephosphorylationGO:000647030.019
positive regulation of macromolecule metabolic processGO:0010604930.019
Human Rat
positive regulation of dna metabolic processGO:005105410.019
negative regulation of cellular biosynthetic processGO:0031327550.019
pericardium developmentGO:006003910.019
regulation of cellular amine metabolic processGO:003323800.019
cell morphogenesisGO:00009022890.019
stem cell proliferationGO:007208940.019
negative regulation of gene expressionGO:0010629650.019
regulation of protein metabolic processGO:0051246560.019
Human Rat
adherens junction organizationGO:003433240.019
detection of stimulus involved in sensory perceptionGO:0050906210.019
blood vessel morphogenesisGO:00485142160.018
regulation of biomineral tissue developmentGO:007016720.018
regulation of system processGO:0044057400.018
Mouse Rat
retina development in camera type eyeGO:00600411460.018
negative regulation of calcium dependent cell cell adhesionGO:004658810.018
negative regulation of biosynthetic processGO:0009890550.018
cytosolic calcium ion transportGO:006040130.018
Human Rat
iron ion homeostasisGO:005507240.018
regulation of protein targetingGO:190353320.018
positive regulation of myeloid cell differentiationGO:004563920.018
ovarian follicle developmentGO:000154120.018
nuclear transportGO:005116940.018
Human
positive regulation of muscle organ developmentGO:004863610.018
regulation of myeloid leukocyte differentiationGO:000276150.018
autophagyGO:000691440.018
specification of organ identityGO:001009220.018
cardiac atrium developmentGO:000323040.018
positive regulation of rho protein signal transductionGO:003502500.017
Mouse
pathway restricted smad protein phosphorylationGO:006038910.017
female sex differentiationGO:004666040.017
epithelial cell morphogenesis involved in gastrulationGO:000338110.017
positive regulation of cell cycleGO:004578730.017
muscle structure developmentGO:00610611960.017
regulation of protein catabolic processGO:004217610.017
regulation of cell activationGO:005086510.017
positive regulation of immune effector processGO:000269930.017
positive regulation of cell proliferationGO:0008284150.017
Rat
aorta developmentGO:003590440.017
dna biosynthetic processGO:007189730.017
negative regulation of cellular metabolic processGO:0031324770.017
phosphorylationGO:0016310690.017
Human Mouse Rat
regulation of cell communicationGO:00106462320.017
Human Mouse Rat
positive regulation of cellular component movementGO:0051272110.017
Human Mouse
cellular response to hormone stimulusGO:0032870390.017
pattern recognition receptor signaling pathwayGO:000222150.017
positive regulation of rna biosynthetic processGO:1902680570.017
Human
mitochondrion organizationGO:000700540.017
cellular biosynthetic processGO:00442492860.017
Human
regulation of molecular functionGO:0065009700.017
Human Rat
regulation of organ morphogenesisGO:2000027350.016
endothelial cell proliferationGO:0001935110.016
cellular component assemblyGO:00226071700.016
transcription dna templatedGO:00063511810.016
Human
positive regulation of muscle tissue developmentGO:190186310.016
atrioventricular valve formationGO:000319030.016
leukocyte migrationGO:0050900150.016
non canonical wnt signaling pathwayGO:0035567130.016
neuron projection morphogenesisGO:00488121610.016
positive regulation of cytosolic calcium ion concentrationGO:000720440.016
Human Mouse Rat
positive regulation of nucleic acid templated transcriptionGO:1903508570.016
Human
nucleobase containing compound metabolic processGO:00061392740.016
Human
leukocyte chemotaxisGO:0030595120.015
growthGO:00400071740.015
viral processGO:001603210.015
neuronal stem cell maintenanceGO:009715020.015
cation homeostasisGO:0055080330.015
Human Mouse Rat
development of primary female sexual characteristicsGO:004654540.015
atrial ventricular junction remodelingGO:000329420.015
mapk cascadeGO:0000165180.015
Human Mouse Rat
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
Human
mitotic dna integrity checkpointGO:004477440.015
organic cyclic compound metabolic processGO:19013603010.015
Human
negative regulation of nucleobase containing compound metabolic processGO:0045934590.015
regulation of apoptotic processGO:0042981980.015
Human Rat
kidney vasculature developmentGO:006144020.015
macrophage chemotaxisGO:004824630.015
phagocytosis engulfmentGO:000691110.015
erythrocyte maturationGO:004324980.015
macromolecule biosynthetic processGO:00090592270.015
Human
phagocytosisGO:000690930.015
determination of left right asymmetry in diencephalonGO:003546240.015
establishment or maintenance of monopolar cell polarityGO:006133920.015
positive regulation of developmental processGO:0051094500.014
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.014
wnt signaling pathway planar cell polarity pathwayGO:006007140.014
retina vasculature development in camera type eyeGO:006129820.014
regulation of synapse assemblyGO:005196330.014
primary neural tube formationGO:001402010.014
positive regulation of cytoskeleton organizationGO:005149530.014
positive regulation of cellular metabolic processGO:0031325940.014
Human Mouse Rat
mitotic sister chromatid segregationGO:000007060.014
hormone biosynthetic processGO:004244630.014
cellular macromolecule metabolic processGO:00442603910.014
Human Rat
protein complex subunit organizationGO:0071822460.014
positive regulation of cellular amine metabolic processGO:003324000.014
regulation of carbohydrate metabolic processGO:000610940.014
tissue migrationGO:0090130370.014
pronephric nephron developmentGO:0039019140.014
maintenance of locationGO:005123540.014
Rat
positive regulation of apoptotic signaling pathwayGO:200123510.014
regulation of cell proliferation involved in heart morphogenesisGO:200013620.014
cellular amino acid metabolic processGO:000652070.014
kidney developmentGO:0001822920.014
developmental programmed cell deathGO:001062340.013
positive regulation of cytokine productionGO:000181920.013
Human
agingGO:000756820.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
regulation of biosynthetic processGO:00098892500.013
Human
regulation of cytokine mediated signaling pathwayGO:000195930.013
meiosis iiGO:000713510.013
multicellular organism growthGO:003526440.013
ameboidal type cell migrationGO:00016671430.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
protein metabolic processGO:00195381830.013
Human Rat
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.013
endothelial cell differentiationGO:0045446200.013
invagination involved in gastrulation with mouth forming secondGO:005510910.013
phosphatidylinositol mediated signalingGO:004801520.013
Mouse
regulation of cellular extravasationGO:000269110.013
establishment of localizationGO:00512342440.013
Human Mouse Rat
positive regulation of response to external stimulusGO:003210390.013
regulation of signalingGO:00230512350.013
Human Mouse Rat
transition metal ion homeostasisGO:005507650.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
epithelial cell differentiation involved in kidney developmentGO:0035850130.012
telomere maintenanceGO:000072310.012
angioblast cell differentiationGO:003577920.012
negative regulation of protein transportGO:005122430.012
Mouse
actin polymerization or depolymerizationGO:000815420.012
response to organic substanceGO:00100331530.012
Mouse
morphogenesis of an epithelial foldGO:006057110.012
negative regulation of biological processGO:00485193040.012
humoral immune response mediated by circulating immunoglobulinGO:000245530.012
cell cycle g1 s phase transitionGO:004484310.012
venous blood vessel developmentGO:006084190.012
negative regulation of nucleic acid templated transcriptionGO:1903507450.012
ubiquitin dependent protein catabolic processGO:000651130.012
odontogenesis of dentin containing toothGO:004247510.012
regulation of neuron apoptotic processGO:0043523170.012
Rat
ventricular cardiac muscle tissue developmentGO:000322930.012
outflow tract morphogenesisGO:000315110.012
leukocyte homeostasisGO:000177620.012
positive regulation of transportGO:005105020.012
Human Rat
regulation of cell substrate adhesionGO:001081010.012
cell morphogenesis involved in differentiationGO:00009041950.012
neuron developmentGO:00486662620.012
transcription elongation from rna polymerase ii promoterGO:000636830.012
negative regulation of signal transductionGO:0009968940.012
hepaticobiliary system developmentGO:0061008980.012
somatic cell dna recombinationGO:001644410.011
regenerationGO:0031099910.011
response to stressGO:00069502630.011
Human Mouse
cellular aromatic compound metabolic processGO:00067252950.011
Human
cell proliferationGO:0008283800.011
Human Rat
carboxylic acid metabolic processGO:0019752220.011
negative regulation of macromolecule biosynthetic processGO:0010558480.011
positive regulation of production of molecular mediator of immune responseGO:000270210.011
kidney morphogenesisGO:0060993150.011
macrophage differentiationGO:003022570.011
positive regulation of cell activationGO:005086710.011
negative regulation of dna metabolic processGO:005105340.011
circulatory system processGO:0003013870.011
Mouse Rat
determination of left right asymmetry in nervous systemGO:003554540.011
regulation of cell motilityGO:2000145460.011
Human Mouse
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
negative regulation of cellular processGO:00485232830.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
lymph vessel morphogenesisGO:0036303250.011
protein modification processGO:00362111000.011
Human Rat
regulation of response to cytokine stimulusGO:006075930.011
organelle organizationGO:00069962270.011
hypothalamus cell differentiationGO:002197940.011
positive regulation of mesenchymal cell proliferationGO:000205310.011
cellular response to organic substanceGO:00713101050.011
negative regulation of myeloid cell differentiationGO:004563810.011
regulation of stem cell proliferationGO:007209120.011
cell cycleGO:0007049930.011
synaptic growth at neuromuscular junctionGO:005112420.011
cell proliferation involved in heart morphogenesisGO:006132320.011
regulation of cell cycleGO:0051726520.011
regulation of cell killingGO:003134120.011
adrenal gland developmentGO:0030325100.010
positive regulation of biological processGO:00485182530.010
Human Mouse Rat
calcium ion transport into cytosolGO:006040230.010
Human Rat
mitotic nuclear divisionGO:0007067180.010
proteasomal protein catabolic processGO:001049820.010
g1 s transition of mitotic cell cycleGO:000008210.010
stem cell differentiationGO:00488631170.010
regulation of leukocyte mediated immunityGO:000270310.010
nucleic acid metabolic processGO:00903042440.010
Human
adherens junction assemblyGO:003433310.010
epithelial cell migrationGO:0010631250.010
oocyte maturationGO:000155640.010

f2r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.020
cancerDOID:16200.020
organ system cancerDOID:005068600.019
hematopoietic system diseaseDOID:7400.019
disease of anatomical entityDOID:700.019
immune system diseaseDOID:291400.019