Danio rerio

0 known processes

dffa

DNA fragmentation factor, alpha polypeptide

(Aliases: zgc:92229)

dffa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.082
larval developmentGO:000216420.071
cellular biosynthetic processGO:00442492860.069
regulation of macromolecule metabolic processGO:00602553170.063
nucleic acid metabolic processGO:00903042440.054
cellular macromolecule metabolic processGO:00442603910.053
heterocycle biosynthetic processGO:00181302150.047
nitrogen compound metabolic processGO:00068073190.047
cellular nitrogen compound metabolic processGO:00346412900.047
cellular nitrogen compound biosynthetic processGO:00442712180.047
maintenance of locationGO:005123540.046
aromatic compound biosynthetic processGO:00194382170.045
regulation of macromolecule biosynthetic processGO:00105562250.045
multicellular organism growthGO:003526440.044
cellular aromatic compound metabolic processGO:00067252950.044
positive regulation of transportGO:005105020.043
regulation of multicellular organism growthGO:004001440.043
nucleobase containing compound biosynthetic processGO:00346542050.042
organic cyclic compound metabolic processGO:19013603010.041
biosynthetic processGO:00090582940.040
organic cyclic compound biosynthetic processGO:19013622230.040
rna metabolic processGO:00160702190.040
cellular macromolecule biosynthetic processGO:00346452240.040
organic substance biosynthetic processGO:19015762890.039
negative regulation of biological processGO:00485193040.039
proteasomal protein catabolic processGO:001049820.038
heterocycle metabolic processGO:00464832900.038
lipid storageGO:001991510.037
macromolecule biosynthetic processGO:00090592270.037
nucleobase containing compound metabolic processGO:00061392740.035
cellular protein catabolic processGO:004425740.035
transcription dna templatedGO:00063511810.035
nucleic acid templated transcriptionGO:00976591810.034
proteolysis involved in cellular protein catabolic processGO:005160330.034
regulation of nitrogen compound metabolic processGO:00511712510.034
regulation of cellular macromolecule biosynthetic processGO:20001122220.033
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.032
regulation of protein ubiquitinationGO:003139630.032
regulation of nucleic acid templated transcriptionGO:19035062130.031
ubiquitin dependent protein catabolic processGO:000651130.031
regulation of primary metabolic processGO:00800903110.031
regulation of nucleobase containing compound metabolic processGO:00192192500.031
gene expressionGO:00104672520.031
rna biosynthetic processGO:00327741810.031
regulation of rna metabolic processGO:00512522240.031
positive regulation of biological processGO:00485182530.030
negative regulation of cellular processGO:00485232830.030
synaptic growth at neuromuscular junctionGO:005112420.030
extrinsic apoptotic signaling pathwayGO:009719130.030
regulation of metabolic processGO:00192223590.030
regulation of protein modification by small protein conjugation or removalGO:190332030.029
purine ribonucleoside monophosphate catabolic processGO:000916940.029
nucleoside monophosphate catabolic processGO:000912540.029
negative regulation of protein phosphorylationGO:000193340.029
regulation of cellular metabolic processGO:00313233200.028
positive regulation of catabolic processGO:000989640.028
response to chemicalGO:00422213200.028
positive regulation of cell cycleGO:004578730.027
regulation of transcription dna templatedGO:00063552130.027
response to drugGO:004249330.027
regulation of bindingGO:005109830.027
regulation of gene expressionGO:00104682650.027
positive regulation of cellular catabolic processGO:003133130.026
atp catabolic processGO:000620040.026
eye developmentGO:00016542770.026
amine metabolic processGO:000930820.026
regulation of rna biosynthetic processGO:20011412130.026
organic acid metabolic processGO:0006082310.026
embryonic organ developmentGO:00485683810.026
modification dependent macromolecule catabolic processGO:004363230.025
ribonucleoside monophosphate catabolic processGO:000915840.025
regulation of biosynthetic processGO:00098892500.025
sensory organ developmentGO:00074233930.025
purine nucleoside monophosphate catabolic processGO:000912840.025
single organism metabolic processGO:00447102170.025
regulation of synapse organizationGO:005080730.025
central nervous system developmentGO:00074173870.025
single organism membrane fusionGO:004480120.025
head developmentGO:00603223030.024
stem cell maintenanceGO:001982740.024
exocytosisGO:000688710.024
meiotic nuclear divisionGO:000712640.024
regulation of metal ion transportGO:001095940.024
modification dependent protein catabolic processGO:001994130.023
nucleocytoplasmic transportGO:000691340.023
regulation of protein transportGO:005122330.023
regulation of establishment of protein localizationGO:007020140.023
cellular amine metabolic processGO:004410620.023
nuclear transportGO:005116940.022
regulation of cellular biosynthetic processGO:00313262450.022
regulation of epithelial cell proliferationGO:005067830.022
regulation of cellular amino acid metabolic processGO:000652100.022
carboxylic acid metabolic processGO:0019752220.022
phagocytosisGO:000690930.022
mitochondrion organizationGO:000700540.022
cellular ketone metabolic processGO:0042180110.022
response to stressGO:00069502630.022
nuclear migrationGO:000709730.022
oxoacid metabolic processGO:0043436310.021
positive regulation of secretion by cellGO:190353210.021
regulation of extrinsic apoptotic signaling pathwayGO:200123630.021
lateral inhibitionGO:004633110.021
cytokinesisGO:000091030.021
regulation of cell activationGO:005086510.021
hemopoiesisGO:00300971830.021
regulation of multicellular organismal processGO:00512392770.021
small molecule metabolic processGO:0044281770.021
endosomal transportGO:001619720.020
regulation of cytokine productionGO:000181730.020
establishment of protein localization to organelleGO:007259440.020
guanosine containing compound metabolic processGO:190106840.020
positive regulation of cellular component biogenesisGO:004408930.020
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
stem cell proliferationGO:007208940.020
regulation of signalingGO:00230512350.020
regulation of protein catabolic processGO:004217610.020
adult behaviorGO:003053420.020
regulation of biological qualityGO:00650082630.020
meiotic cell cycle processGO:190304630.020
regulation of cellular amine metabolic processGO:003323800.020
heart developmentGO:00075073130.020
cellular amino acid metabolic processGO:000652070.019
membrane fusionGO:006102520.019
regulation of synapse assemblyGO:005196330.019
guanosine containing compound catabolic processGO:190106920.019
system processGO:00030081850.019
signal transduction in absence of ligandGO:003803410.019
hematopoietic or lymphoid organ developmentGO:00485341910.019
protein metabolic processGO:00195381830.019
signal transductionGO:00071654550.019
compound eye developmentGO:004874920.019
regulation of nucleoside metabolic processGO:000911820.019
regulation of meiotic cell cycleGO:005144510.019
regulation of cellular ketone metabolic processGO:001056570.019
leukocyte proliferationGO:007066110.018
embryo development ending in birth or egg hatchingGO:00097922710.018
cell surface receptor signaling pathwayGO:00071663250.018
positive regulation of map kinase activityGO:004340630.018
brain developmentGO:00074202930.018
positive regulation of cellular processGO:00485222010.018
growthGO:00400071740.018
regulation of cell shapeGO:000836010.018
regulation of cytoplasmic transportGO:190364940.018
gtp catabolic processGO:000618420.018
gtp metabolic processGO:004603940.018
organelle organizationGO:00069962270.018
immune system processGO:00023762410.018
regulation of dendrite developmentGO:005077330.018
protein localization to nucleusGO:003450430.018
regulation of synaptic plasticityGO:004816710.017
protein import into nucleusGO:000660630.017
positive regulation of apoptotic signaling pathwayGO:200123510.017
nuclear importGO:005117030.017
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.017
chordate embryonic developmentGO:00430092710.017
female gonad developmentGO:000858540.017
regulation of purine nucleotide catabolic processGO:003312120.017
regulation of intracellular protein transportGO:003315730.017
regulation of circadian rhythmGO:004275240.017
tissue remodelingGO:004877140.017
positive regulation of nucleoside metabolic processGO:004597910.017
cellular component morphogenesisGO:00329893360.017
single organism nuclear importGO:190259330.017
regulation of erk1 and erk2 cascadeGO:007037240.017
regulation of developmental processGO:00507932470.017
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.017
fertilizationGO:000956630.017
protein targeting to nucleusGO:004474430.016
golgi vesicle transportGO:004819330.016
organonitrogen compound metabolic processGO:1901564740.016
positive regulation of purine nucleotide catabolic processGO:003312310.016
female sex differentiationGO:004666040.016
response to topologically incorrect proteinGO:003596620.016
single fertilizationGO:000733830.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
regulation of response to stimulusGO:00485832690.016
neurotransmitter transportGO:000683620.016
protein importGO:001703830.016
regulation of stem cell proliferationGO:007209120.016
positive regulation of nucleotide catabolic processGO:003081310.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.016
regulation of nucleotide catabolic processGO:003081120.016
positive regulation of cell activationGO:005086710.016
hormone secretionGO:004687920.016
positive regulation of cellular amine metabolic processGO:003324000.016
regulation of cell communicationGO:00106462320.016
primary neural tube formationGO:001402010.016
negative regulation of protein kinase activityGO:000646940.016
mitotic dna integrity checkpointGO:004477440.016
transcription from rna polymerase ii promoterGO:0006366800.016
development of primary female sexual characteristicsGO:004654540.016
regulation of blood pressureGO:000821710.016
cellular protein metabolic processGO:00442671290.015
erk1 and erk2 cascadeGO:007037140.015
protein heterooligomerizationGO:005129110.015
peptide metabolic processGO:000651810.015
cell substrate adhesionGO:003158940.015
regulation of receptor activityGO:001046920.015
regulation of protein complex assemblyGO:004325430.015
autophagyGO:000691440.015
stem cell divisionGO:001714510.015
regulation of dna replicationGO:000627530.015
cell morphogenesisGO:00009022890.015
peptidyl serine phosphorylationGO:001810510.015
protein localization to plasma membraneGO:007265910.015
meiosis iGO:000712710.015
morphogenesis of an epitheliumGO:00020093330.015
organelle fusionGO:004828430.015
regulation of protein bindingGO:004339330.015
positive regulation of secretionGO:005104710.015
regulation of dendrite morphogenesisGO:004881430.015
regulation of chromosome segregationGO:005198310.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
cognitionGO:005089010.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
regulation of reproductive processGO:200024140.014
regulation of organ growthGO:004662030.014
mononuclear cell proliferationGO:003294310.014
developmental growthGO:00485891660.014
cellular response to oxygen levelsGO:007145310.014
peptidyl serine modificationGO:001820920.014
immune system developmentGO:00025201910.014
cellular response to chemical stimulusGO:00708871570.014
regulation of protein localization to nucleusGO:190018020.014
somatic muscle developmentGO:000752540.014
regulation of hormone secretionGO:004688320.014
tube closureGO:006060610.014
cellular component movementGO:00069283350.014
regulation of ion transmembrane transporter activityGO:003241220.014
peptide transportGO:001583310.014
i kappab kinase nf kappab signalingGO:000724940.014
phosphorus metabolic processGO:00067931090.014
meiotic chromosome segregationGO:004513230.014
deathGO:00162651210.014
epithelial cell differentiationGO:00308551160.014
positive regulation of immune effector processGO:000269930.014
regulation of transporter activityGO:003240920.014
protein polymerizationGO:005125840.014
long chain fatty acid metabolic processGO:000167610.014
regulation of response to cytokine stimulusGO:006075930.014
negative regulation of kinase activityGO:003367340.014
eye morphogenesisGO:00485921440.013
muscle cell migrationGO:001481240.013
developmental programmed cell deathGO:001062340.013
generation of neuronsGO:00486993850.013
endocrine processGO:005088620.013
secondary metabolic processGO:001974830.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
single organism localizationGO:19025782250.013
negative regulation of nuclear divisionGO:005178430.013
negative regulation of cytokine productionGO:000181810.013
cytoskeleton dependent cytokinesisGO:006164030.013
negative regulation of epithelial cell proliferationGO:005068010.013
response to vitaminGO:003327330.013
regulation of blood vessel sizeGO:005088020.013
regulation of transmembrane transporter activityGO:002289820.013
cellular response to hypoxiaGO:007145610.013
protein secretionGO:000930610.013
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.013
lysosomal transportGO:000704120.013
positive regulation of protein complex assemblyGO:003133420.013
cell cycle g1 s phase transitionGO:004484310.013
regulation of cell deathGO:00109411030.013
camera type eye developmentGO:00430102220.013
protein modification processGO:00362111000.013
digestive system developmentGO:00551232890.013
negative regulation of catabolic processGO:000989530.013
oocyte anterior posterior axis specificationGO:000731440.013
regulation of gtpase activityGO:004308720.013
multicellular organismal response to stressGO:003355520.013
cellular modified amino acid metabolic processGO:000657530.013
regulation of gtp catabolic processGO:003312420.013
positive regulation of cytokine productionGO:000181920.013
neuron differentiationGO:00301823530.013
sleepGO:003043110.013
production of molecular mediator of immune responseGO:000244020.013
cortical cytoskeleton organizationGO:003086510.013
multicellular organismal metabolic processGO:004423620.012
negative regulation of protein transportGO:005122430.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
rna localizationGO:000640340.012
neurotransmitter secretionGO:000726920.012
negative regulation of cellular catabolic processGO:003133030.012
lymphocyte proliferationGO:004665110.012
cellular amide metabolic processGO:004360340.012
adherens junction organizationGO:003433240.012
response to unfolded proteinGO:000698620.012
regulation of stem cell differentiationGO:200073640.012
regulation of signal transductionGO:00099662250.012
cellular response to decreased oxygen levelsGO:003629410.012
regulation of protein targetingGO:190353320.012
homeostatic processGO:00425921420.012
regulation of systemic arterial blood pressureGO:000307310.012
single organism transportGO:00447652060.012
regulation of jak stat cascadeGO:004642530.012
protein k48 linked ubiquitinationGO:007093610.012
regulation of reactive oxygen species metabolic processGO:200037720.012
positive regulation of dna metabolic processGO:005105410.012
germ line stem cell maintenanceGO:003071820.012
response to organic substanceGO:00100331530.012
cellular protein modification processGO:00064641000.012
regionalizationGO:00030022740.012
protein dephosphorylationGO:000647030.012
g1 s transition of mitotic cell cycleGO:000008210.012
cell motilityGO:00488702440.012
establishment of localizationGO:00512342440.012
cell agingGO:000756920.012
macromolecule modificationGO:00434121110.012
regulation of cellular protein catabolic processGO:190336210.012
sensory organ morphogenesisGO:00905962000.012
sensory perception of painGO:001923310.012
regulation of nucleocytoplasmic transportGO:004682220.012
negative regulation of protein complex assemblyGO:003133310.012
post embryonic organ developmentGO:004856940.012
cellular response to nutrient levelsGO:003166920.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
epithelial tube morphogenesisGO:00605621480.012
positive regulation of canonical wnt signaling pathwayGO:009026340.012
response to external stimulusGO:00096052640.012
cellular response to extracellular stimulusGO:003166820.012
response to corticosteroidGO:003196010.012
positive regulation of cellular metabolic processGO:0031325940.012
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.012
tube morphogenesisGO:00352393490.012
regulation of wound healingGO:006104120.012
positive regulation of metabolic processGO:00098931080.012
response to uvGO:000941130.012
response to nutrientGO:000758430.011
transportGO:00068102200.011
regulation of calcium ion transportGO:005192420.011
dna templated transcription elongationGO:000635430.011
blood vessel developmentGO:00015682460.011
intracellular signal transductionGO:0035556850.011
positive regulation of cell divisionGO:005178120.011
response to monosaccharideGO:003428430.011
cell migrationGO:00164772370.011
response to hexoseGO:000974630.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
positive regulation of stress activated mapk cascadeGO:003287430.011
establishment of protein localization to plasma membraneGO:009000210.011
regulation of protein import into nucleusGO:004230620.011
positive regulation of cytoskeleton organizationGO:005149530.011
cellular lipid catabolic processGO:004424230.011
cellular component disassemblyGO:002241110.011
regulation of tube sizeGO:003515020.011
response to glucocorticoidGO:005138410.011
peptidyl lysine acetylationGO:001839420.011
cortical actin cytoskeleton organizationGO:003086610.011
b cell activationGO:004211320.011
heart morphogenesisGO:00030071560.011
positive regulation of chromosome organizationGO:200125210.011
localization of cellGO:00516742440.011
wound healingGO:0042060900.011
response to other organismGO:0051707970.011
negative regulation of metabolic processGO:0009892860.011
transcription elongation from rna polymerase ii promoterGO:000636830.011
hormone transportGO:000991420.011
chemosensory behaviorGO:000763510.011
cellular response to external stimulusGO:007149620.011
regulation of epithelial to mesenchymal transitionGO:001071730.011
nuclear exportGO:005116810.011
cellular response to biotic stimulusGO:007121630.011
protein stabilizationGO:005082120.011
somite developmentGO:0061053960.011
cation transportGO:0006812810.011
regulation of carbohydrate metabolic processGO:000610940.010
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.010
regulation of neurotransmitter transportGO:005158810.010
positive regulation of macromolecule metabolic processGO:0010604930.010
membrane lipid biosynthetic processGO:004646720.010
interspecies interaction between organismsGO:004441940.010
calcium ion dependent exocytosisGO:001715610.010
regulation of microtubule cytoskeleton organizationGO:007050730.010
negative regulation of secretion by cellGO:190353120.010
double strand break repairGO:000630230.010
response to abiotic stimulusGO:00096281220.010
protein acylationGO:004354330.010
positive regulation of stem cell proliferationGO:200064810.010
recombinational repairGO:000072510.010
negative regulation of apoptotic processGO:0043066550.010
negative regulation of ras protein signal transductionGO:004658010.010
embryonic limb morphogenesisGO:003032620.010
negative regulation of cell communicationGO:0010648960.010
ameboidal type cell migrationGO:00016671430.010
b cell differentiationGO:003018310.010
neuroblast proliferationGO:000740520.010
regulation of mrna processingGO:005068430.010
endoplasmic reticulum unfolded protein responseGO:003096820.010
locomotionGO:00400113130.010
protein homooligomerizationGO:005126030.010
protein complex disassemblyGO:004324110.010
fatty acid biosynthetic processGO:000663340.010
establishment of synaptic vesicle localizationGO:009748010.010
cell part morphogenesisGO:00329902460.010
regulation of multicellular organismal developmentGO:20000262230.010
cellular component assemblyGO:00226071700.010
positive regulation of small gtpase mediated signal transductionGO:005105710.010

dffa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.034
disease of metabolismDOID:001466700.034
disease of anatomical entityDOID:700.027
musculoskeletal system diseaseDOID:1700.017
muscle tissue diseaseDOID:6600.014
muscular diseaseDOID:008000000.014
nervous system diseaseDOID:86300.014
myopathyDOID:42300.012
immune system diseaseDOID:291400.011
cancerDOID:16200.011
organ system cancerDOID:005068600.011
disease of cellular proliferationDOID:1456600.011