Danio rerio

42 known processes

llgl1

lethal giant larvae homolog 1 (Drosophila)

(Aliases: zgc:153337,MGC153337)

llgl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.110
cellular macromolecule metabolic processGO:00442603910.094
central nervous system developmentGO:00074173870.075
signal transductionGO:00071654550.070
response to chemicalGO:00422213200.065
embryonic organ developmentGO:00485683810.061
muscle structure developmentGO:00610611960.057
cell morphogenesisGO:00009022890.056
generation of neuronsGO:00486993850.056
positive regulation of biological processGO:00485182530.056
sensory organ developmentGO:00074233930.055
digestive system developmentGO:00551232890.054
nucleic acid metabolic processGO:00903042440.053
aromatic compound biosynthetic processGO:00194382170.052
neuron differentiationGO:00301823530.051
cell surface receptor signaling pathwayGO:00071663250.051
regulation of metabolic processGO:00192223590.051
regulation of gene expressionGO:00104682650.049
cellular component morphogenesisGO:00329893360.049
negative regulation of cellular processGO:00485232830.049
regulation of developmental processGO:00507932470.046
cellular nitrogen compound biosynthetic processGO:00442712180.046
agingGO:000756820.044
morphogenesis of an epitheliumGO:00020093330.044
tube morphogenesisGO:00352393490.044
cell projection morphogenesisGO:00488582440.043
maintenance of locationGO:005123540.042
nitrogen compound metabolic processGO:00068073190.042
eye developmentGO:00016542770.042
cellular component movementGO:00069283350.042
regulation of cellular metabolic processGO:00313233200.042
gene expressionGO:00104672520.040
positive regulation of cell cycleGO:004578730.040
organic cyclic compound metabolic processGO:19013603010.040
nucleobase containing compound metabolic processGO:00061392740.039
stem cell maintenanceGO:001982740.039
organelle organizationGO:00069962270.038
regulation of signal transductionGO:00099662250.038
vasculature developmentGO:00019442780.037
camera type eye developmentGO:00430102220.037
nucleobase containing compound biosynthetic processGO:00346542050.037
cell motilityGO:00488702440.036
locomotionGO:00400113130.035
regulation of response to stimulusGO:00485832690.035
cellular biosynthetic processGO:00442492860.034
muscle tissue developmentGO:00605371100.034
lateral inhibitionGO:004633110.034
regulation of synapse assemblyGO:005196330.034
heterocycle biosynthetic processGO:00181302150.034
cellular nitrogen compound metabolic processGO:00346412900.034
heterocycle metabolic processGO:00464832900.034
brain developmentGO:00074202930.034
heart developmentGO:00075073130.034
biosynthetic processGO:00090582940.033
regulation of nucleobase containing compound metabolic processGO:00192192500.033
system processGO:00030081850.033
striated muscle cell differentiationGO:00511461290.032
response to external stimulusGO:00096052640.032
head developmentGO:00603223030.032
cell migrationGO:00164772370.032
gastrulationGO:00073692080.032
organic cyclic compound biosynthetic processGO:19013622230.032
rna biosynthetic processGO:00327741810.031
cellular aromatic compound metabolic processGO:00067252950.031
lipid storageGO:001991510.031
blood vessel developmentGO:00015682460.030
regulation of multicellular organismal processGO:00512392770.030
regulation of macromolecule metabolic processGO:00602553170.030
regulation of biological qualityGO:00650082630.029
negative regulation of biological processGO:00485193040.029
nucleic acid templated transcriptionGO:00976591810.029
cell projection organizationGO:00300302840.029
single organism metabolic processGO:00447102170.029
neuron developmentGO:00486662620.029
phagocytosisGO:000690930.029
cell part morphogenesisGO:00329902460.028
regulation of primary metabolic processGO:00800903110.028
digestive tract developmentGO:00485652650.028
regulation of protein catabolic processGO:004217610.028
forebrain developmentGO:0030900960.028
regulation of neural precursor cell proliferationGO:200017730.027
localization of cellGO:00516742440.027
regulation of biosynthetic processGO:00098892500.027
cellular response to chemical stimulusGO:00708871570.027
macromolecule biosynthetic processGO:00090592270.027
digestive tract morphogenesisGO:00485462310.027
cognitionGO:005089010.027
response to alkaloidGO:004327920.027
regulation of synapse organizationGO:005080730.026
retina development in camera type eyeGO:00600411460.026
regulation of stem cell proliferationGO:007209120.026
embryo development ending in birth or egg hatchingGO:00097922710.026
cell morphogenesis involved in differentiationGO:00009041950.026
regulation of nitrogen compound metabolic processGO:00511712510.026
positive regulation of transportGO:005105020.026
regionalizationGO:00030022740.026
stem cell divisionGO:001714510.026
multicellular organism growthGO:003526440.026
extrinsic apoptotic signaling pathwayGO:009719130.025
regulation of rna metabolic processGO:00512522240.025
rna metabolic processGO:00160702190.025
nucleocytoplasmic transportGO:000691340.025
single organism organelle organizationGO:19025891990.025
regulation of transcription dna templatedGO:00063552130.025
regulation of multicellular organismal developmentGO:20000262230.025
neurological system processGO:0050877620.025
regulation of cytokine productionGO:000181730.024
positive regulation of cellular processGO:00485222010.024
modification dependent protein catabolic processGO:001994130.024
transcription dna templatedGO:00063511810.024
negative regulation of protein phosphorylationGO:000193340.024
stem cell proliferationGO:007208940.024
response to stressGO:00069502630.024
chordate embryonic developmentGO:00430092710.024
determination of heart left right asymmetryGO:00613711170.024
striated muscle tissue developmentGO:00147061100.024
regulation of macromolecule biosynthetic processGO:00105562250.024
neuron projection morphogenesisGO:00488121610.023
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.023
angiogenesisGO:00015251580.023
amine metabolic processGO:000930820.023
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.023
embryonic organ morphogenesisGO:00485622740.023
proteasomal protein catabolic processGO:001049820.023
determination of left right symmetryGO:00073681790.023
regulation of establishment of protein localizationGO:007020140.022
blood vessel morphogenesisGO:00485142160.022
muscle organ developmentGO:00075171010.022
cellular protein catabolic processGO:004425740.022
response to organic substanceGO:00100331530.022
protein localization to nucleusGO:003450430.022
cell substrate adhesionGO:003158940.022
regulation of cell differentiationGO:00455951420.022
regulation of signalingGO:00230512350.022
hematopoietic or lymphoid organ developmentGO:00485341910.022
cellular component disassemblyGO:002241110.022
immune system developmentGO:00025201910.021
apoptotic processGO:00069151160.021
regulation of extrinsic apoptotic signaling pathwayGO:200123630.021
cellular amine metabolic processGO:004410620.021
establishment of protein localization to organelleGO:007259440.021
establishment of localizationGO:00512342440.021
chemosensory behaviorGO:000763510.021
regulation of cellular ketone metabolic processGO:001056570.021
enzyme linked receptor protein signaling pathwayGO:00071671060.021
cellular response to external stimulusGO:007149620.021
single organism transportGO:00447652060.021
growthGO:00400071740.021
regulation of cell communicationGO:00106462320.020
protein metabolic processGO:00195381830.020
regulation of cellular biosynthetic processGO:00313262450.020
regulation of rna biosynthetic processGO:20011412130.020
proteolysis involved in cellular protein catabolic processGO:005160330.020
gland developmentGO:00487321430.020
nuclear transportGO:005116940.020
regulation of reproductive processGO:200024140.020
muscle cell differentiationGO:00426921390.020
cell matrix adhesionGO:000716040.020
convergent extensionGO:00600261180.020
actin polymerization or depolymerizationGO:000815420.020
cellular response to radiationGO:007147840.020
membrane invaginationGO:001032410.020
hemopoiesisGO:00300971830.020
organic substance biosynthetic processGO:19015762890.019
heart morphogenesisGO:00030071560.019
determination of bilateral symmetryGO:00098552040.019
negative regulation of developmental processGO:0051093650.019
ubiquitin dependent protein catabolic processGO:000651130.019
regulation of cellular amine metabolic processGO:003323800.019
regulation of apoptotic processGO:0042981980.019
embryonic skeletal system developmentGO:0048706970.019
regulation of cell shapeGO:000836010.019
regulation of cellular amino acid metabolic processGO:000652100.019
modification dependent macromolecule catabolic processGO:004363230.018
cell morphogenesis involved in neuron differentiationGO:00486671630.018
axon developmentGO:00615641660.018
regulation of multicellular organism growthGO:004001440.018
regulation of protein transportGO:005122330.018
negative regulation of metabolic processGO:0009892860.018
cell cycle g1 s phase transitionGO:004484310.018
phagocytosis engulfmentGO:000691110.018
sensory organ morphogenesisGO:00905962000.018
cellular ketone metabolic processGO:0042180110.018
zymogen activationGO:003163830.018
regulation of epithelial cell proliferationGO:005067830.018
transportGO:00068102200.018
regulation of metal ion transportGO:001095940.018
olfactory lobe developmentGO:002198840.018
regulation of cytoplasmic transportGO:190364940.018
septum transversum developmentGO:000334340.018
immune system processGO:00023762410.018
skeletal muscle organ developmentGO:0060538780.018
regulation of programmed cell deathGO:00430671010.017
negative regulation of catabolic processGO:000989530.017
taxisGO:00423301090.017
regulation of cell activationGO:005086510.017
gtp catabolic processGO:000618420.017
protein importGO:001703830.017
g1 s transition of mitotic cell cycleGO:000008210.017
phosphate containing compound metabolic processGO:00067961080.017
positive regulation of catabolic processGO:000989640.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
cellular response to oxygen levelsGO:007145310.017
anterior posterior pattern specificationGO:00099521520.017
mitochondrion organizationGO:000700540.017
regulation of mrna processingGO:005068430.017
single organism nuclear importGO:190259330.017
positive regulation of cellular component biogenesisGO:004408930.017
adult behaviorGO:003053420.017
specification of symmetryGO:00097992040.016
cellular macromolecule biosynthetic processGO:00346452240.016
stem cell differentiationGO:00488631170.016
signal transduction in absence of ligandGO:003803410.016
developmental growthGO:00485891660.016
synaptic growth at neuromuscular junctionGO:005112420.016
positive regulation of cytokine productionGO:000181920.016
regulation of protein complex assemblyGO:004325430.016
somatic stem cell maintenanceGO:003501910.016
cell proliferationGO:0008283800.016
negative regulation of gene expressionGO:0010629650.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
circulatory system processGO:0003013870.016
meiotic nuclear divisionGO:000712640.016
guanosine containing compound metabolic processGO:190106840.016
embryonic heart tube developmentGO:00350501330.016
positive regulation of stress activated mapk cascadeGO:003287430.016
cellular amino acid metabolic processGO:000652070.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
adherens junction organizationGO:003433240.016
cellular response to lipopolysaccharideGO:007122230.016
neuron projection developmentGO:00311751800.016
cilium assemblyGO:0042384580.016
cellular carbohydrate metabolic processGO:004426240.016
regulation of bindingGO:005109830.016
intracellular signal transductionGO:0035556850.016
response to carbohydrateGO:000974330.016
positive regulation of cellular metabolic processGO:0031325940.015
positive regulation of cellular catabolic processGO:003133130.015
post embryonic organ developmentGO:004856940.015
mononuclear cell proliferationGO:003294310.015
positive regulation of protein complex assemblyGO:003133420.015
mesenchyme developmentGO:00604851270.015
dorsal ventral pattern formationGO:00099531250.015
erythrocyte homeostasisGO:0034101550.015
renal tubule morphogenesisGO:006133310.015
protein targeting to nucleusGO:004474430.015
eye morphogenesisGO:00485921440.015
regulation of nucleocytoplasmic transportGO:004682220.015
protein homooligomerizationGO:005126030.015
protein import into nucleusGO:000660630.015
cellular protein metabolic processGO:00442671290.015
positive regulation of map kinase activityGO:004340630.015
response to woundingGO:00096111160.015
autophagyGO:000691440.015
urogenital system developmentGO:0001655970.015
ear developmentGO:00435831270.015
renal system developmentGO:0072001940.014
regulation of protein import into nucleusGO:004230620.014
cilium organizationGO:0044782710.014
chemotaxisGO:00069351040.014
tissue remodelingGO:004877140.014
lymphocyte proliferationGO:004665110.014
regulation of intracellular protein transportGO:003315730.014
protein dephosphorylationGO:000647030.014
phosphorus metabolic processGO:00067931090.014
muscle cell developmentGO:00550011150.014
positive regulation of cytoskeleton organizationGO:005149530.014
small molecule metabolic processGO:0044281770.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
neuron neuron synaptic transmissionGO:000727010.014
organic acid metabolic processGO:0006082310.014
epithelial tube morphogenesisGO:00605621480.014
positive regulation of metabolic processGO:00098931080.014
response to monosaccharideGO:003428430.014
regulation of organ growthGO:004662030.014
regulation of blood pressureGO:000821710.014
oxoacid metabolic processGO:0043436310.014
nuclear importGO:005117030.014
kidney developmentGO:0001822920.013
response to uvGO:000941130.013
regulation of circadian rhythmGO:004275240.013
regulation of inflammatory responseGO:005072720.013
locomotor rhythmGO:004547530.013
regulation of autophagyGO:001050630.013
protein polymerizationGO:005125840.013
establishment of endothelial barrierGO:006102830.013
leukocyte proliferationGO:007066110.013
regulation of cell substrate adhesionGO:001081010.013
carbohydrate homeostasisGO:003350010.013
deathGO:00162651210.013
guanosine containing compound catabolic processGO:190106920.013
behaviorGO:0007610740.013
transmembrane transportGO:00550851200.013
sequestering of metal ionGO:005123830.013
female gonad developmentGO:000858540.013
positive regulation of dna metabolic processGO:005105410.013
regulation of stem cell differentiationGO:200073640.013
homeostatic processGO:00425921420.013
regulation of cellular component movementGO:0051270550.013
embryonic heart tube morphogenesisGO:00031431080.013
embryonic limb morphogenesisGO:003032620.013
negative regulation of synapse assemblyGO:005196420.013
regulation of erk1 and erk2 cascadeGO:007037240.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
multi organism processGO:00517041340.013
b cell differentiationGO:003018310.013
response to abiotic stimulusGO:00096281220.013
hatchingGO:003518840.013
striated muscle cell developmentGO:00550021080.013
b cell activationGO:004211320.013
macromolecule modificationGO:00434121110.013
liver developmentGO:0001889960.013
i kappab kinase nf kappab signalingGO:000724940.013
negative regulation of protein transportGO:005122430.013
neuroblast proliferationGO:000740520.013
regulation of intracellular signal transductionGO:1902531570.012
regulation of muscle contractionGO:000693730.012
synaptic target recognitionGO:000803910.012
negative regulation of kinase activityGO:003367340.012
regulation of cell deathGO:00109411030.012
organonitrogen compound metabolic processGO:1901564740.012
positive regulation of cellular amine metabolic processGO:003324000.012
regulation of locomotionGO:0040012550.012
single organism localizationGO:19025782250.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
multi organism cellular processGO:004476420.012
protein localization to plasma membraneGO:007265910.012
regulation of cell migrationGO:0030334400.012
olfactory bulb developmentGO:002177240.012
retina morphogenesis in camera type eyeGO:0060042790.012
development of primary female sexual characteristicsGO:004654540.012
axonogenesisGO:00074091520.012
negative regulation of protein kinase activityGO:000646940.012
multicellular organismal signalingGO:0035637220.012
carboxylic acid metabolic processGO:0019752220.012
somatic muscle developmentGO:000752540.012
nephron morphogenesisGO:007202820.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
cellular response to light stimulusGO:007148240.012
programmed cell deathGO:00125011190.012
epithelial cell differentiationGO:00308551160.012
cilium morphogenesisGO:0060271850.012
regulation of reactive oxygen species metabolic processGO:200037720.012
regulation of cell matrix adhesionGO:000195210.012
female sex differentiationGO:004666040.012
regulation of protein targetingGO:190353320.012
myeloid cell differentiationGO:0030099860.012
cellular response to extracellular stimulusGO:003166820.012
negative regulation of epithelial cell proliferationGO:005068010.012
actin filament polymerizationGO:003004120.012
transcription from rna polymerase ii promoterGO:0006366800.012
regulation of purine nucleotide catabolic processGO:003312120.012
negative regulation of cell communicationGO:0010648960.012
energy reserve metabolic processGO:000611220.012
regulation of mesenchymal cell proliferationGO:001046410.012
positive regulation of response to stimulusGO:0048584800.012
regenerationGO:0031099910.012
negative regulation of cytokine productionGO:000181810.012
glial cell migrationGO:000834730.012
appendage developmentGO:0048736800.011
cranial nerve developmentGO:0021545420.011
interspecies interaction between organismsGO:004441940.011
inner ear developmentGO:00488391260.011
cell fate commitmentGO:0045165990.011
negative regulation of macromolecule metabolic processGO:0010605760.011
wnt signaling pathwayGO:0016055800.011
mesoderm developmentGO:0007498880.011
negative regulation of mapk cascadeGO:004340940.011
cell deathGO:00082191210.011
morphogenesis of an epithelial sheetGO:0002011490.011
negative regulation of cytoplasmic transportGO:190365020.011
developmental growth involved in morphogenesisGO:0060560860.011
nephron tubule morphogenesisGO:007207810.011
action potentialGO:0001508190.011
pancreas developmentGO:0031016840.011
notochord developmentGO:0030903540.011
regulation of blood vessel sizeGO:005088020.011
cellular response to decreased oxygen levelsGO:003629410.011
cellular component assemblyGO:00226071700.011
sensory perception of painGO:001923310.011
cellular response to hypoxiaGO:007145610.011
positive regulation of epithelial cell differentiationGO:003085820.011
regulation of anatomical structure morphogenesisGO:00226031300.011
cartilage developmentGO:0051216960.011
ion transportGO:00068111140.011
retinal rod cell developmentGO:004654840.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.011
ameboidal type cell migrationGO:00016671430.011
cellular response to nutrient levelsGO:003166920.011
cytosolic calcium ion transportGO:006040130.011
camera type eye morphogenesisGO:00485931080.011
cell substrate junction assemblyGO:000704420.011
smooth muscle contractionGO:000693920.011
peptidyl lysine acetylationGO:001839420.011
regulation of carbohydrate metabolic processGO:000610940.011
regulation of nucleoside metabolic processGO:000911820.011
skeletal muscle tissue developmentGO:0007519670.011
protein modification processGO:00362111000.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
regulation of protein localization to nucleusGO:190018020.011
regulation of sodium ion transportGO:000202820.010
response to other organismGO:0051707970.010
symbiosis encompassing mutualism through parasitismGO:004440340.010
cellular protein modification processGO:00064641000.010
somite developmentGO:0061053960.010
forebrain cell migrationGO:002188510.010
catechol containing compound metabolic processGO:000971220.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
rna localizationGO:000640340.010
negative regulation of sequestering of calcium ionGO:005128340.010
negative regulation of cell differentiationGO:0045596460.010
sensory perception of chemical stimulusGO:000760630.010
regulation of cell proliferationGO:0042127370.010
positive regulation of epithelial cell proliferationGO:005067910.010
cell cycle arrestGO:000705010.010
meiotic cell cycle processGO:190304630.010
gtp metabolic processGO:004603940.010
positive regulation of neuron deathGO:190121610.010
inositol lipid mediated signalingGO:004801720.010
neuronal action potentialGO:0019228180.010
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.010
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.010
canonical wnt signaling pathwayGO:0060070480.010
blood circulationGO:0008015870.010
positive regulation of stem cell proliferationGO:200064810.010
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.010
cytokinesisGO:000091030.010
erythrocyte differentiationGO:0030218540.010
lipid homeostasisGO:005508830.010
organism emergence from protective structureGO:007168440.010
protein acetylationGO:000647320.010
response to radiationGO:0009314510.010
cell cycleGO:0007049930.010
cellular response to biotic stimulusGO:007121630.010
heart contractionGO:0060047710.010

llgl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.051
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
nervous system diseaseDOID:86300.017
musculoskeletal system diseaseDOID:1700.015
sensory system diseaseDOID:005015500.014
eye and adnexa diseaseDOID:149200.014
disease of metabolismDOID:001466700.013
organ system cancerDOID:005068600.011
eye diseaseDOID:561400.010