Danio rerio

0 known processes

palb2

partner and localizer of BRCA2

(Aliases: Fancn,si:ch211-14k19.9)

palb2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repairGO:000630230.343
aromatic compound biosynthetic processGO:00194382170.309
nitrogen compound metabolic processGO:00068073190.249
signal transductionGO:00071654550.231
regulation of rna biosynthetic processGO:20011412130.199
cilium assemblyGO:0042384580.180
organic substance biosynthetic processGO:19015762890.162
nucleic acid metabolic processGO:00903042440.156
nucleobase containing compound metabolic processGO:00061392740.147
meiotic chromosome segregationGO:004513230.144
regionalizationGO:00030022740.133
determination of left right symmetryGO:00073681790.130
mitotic dna integrity checkpointGO:004477440.124
nucleobase containing compound biosynthetic processGO:00346542050.123
dna catabolic processGO:000630810.120
cell morphogenesisGO:00009022890.119
single organism metabolic processGO:00447102170.118
regulation of transcription dna templatedGO:00063552130.111
positive regulation of cellular processGO:00485222010.107
cellular macromolecule metabolic processGO:00442603910.106
regulation of macromolecule biosynthetic processGO:00105562250.105
gene expressionGO:00104672520.103
single organism reproductive processGO:0044702400.102
spermatid differentiationGO:004851520.098
meiotic nuclear divisionGO:000712640.096
sexual reproductionGO:0019953360.096
chromosome organizationGO:0051276310.095
digestive system developmentGO:00551232890.092
cilium morphogenesisGO:0060271850.092
cellular component morphogenesisGO:00329893360.091
transcription from rna polymerase ii promoterGO:0006366800.089
heterocycle metabolic processGO:00464832900.087
specification of symmetryGO:00097992040.085
microtubule organizing center organizationGO:003102310.085
regulation of nucleic acid templated transcriptionGO:19035062130.084
response to radiationGO:0009314510.084
organic cyclic compound biosynthetic processGO:19013622230.083
cell cycle g2 m phase transitionGO:004483940.083
positive regulation of metabolic processGO:00098931080.082
g2 m transition of mitotic cell cycleGO:000008640.081
multicellular organism reproductionGO:0032504350.077
cellular aromatic compound metabolic processGO:00067252950.077
macromolecule biosynthetic processGO:00090592270.076
organelle organizationGO:00069962270.075
organic cyclic compound metabolic processGO:19013603010.073
mitotic dna damage checkpointGO:004477340.073
cellular nitrogen compound metabolic processGO:00346412900.073
regulation of protein transportGO:005122330.071
regulation of gene expressionGO:00104682650.070
regulation of cellular metabolic processGO:00313233200.068
dna biosynthetic processGO:007189730.068
cilium organizationGO:0044782710.067
cell projection morphogenesisGO:00488582440.067
single organism organelle organizationGO:19025891990.064
meiotic cell cycle processGO:190304630.063
negative regulation of biological processGO:00485193040.063
regulation of developmental processGO:00507932470.062
apoptotic processGO:00069151160.062
response to abiotic stimulusGO:00096281220.062
meiosis iGO:000712710.060
response to inorganic substanceGO:0010035380.059
regulation of multicellular organism growthGO:004001440.058
regulation of nitrogen compound metabolic processGO:00511712510.058
histone modificationGO:0016570200.058
embryonic organ morphogenesisGO:00485622740.057
regulation of response to stimulusGO:00485832690.057
programmed cell deathGO:00125011190.057
cell projection assemblyGO:0030031640.056
cellular protein metabolic processGO:00442671290.054
negative regulation of cellular processGO:00485232830.053
larval developmentGO:000216420.052
g2 dna damage checkpointGO:003157230.052
protein metabolic processGO:00195381830.051
cellular protein catabolic processGO:004425740.051
regulation of apoptotic processGO:0042981980.050
cellular component movementGO:00069283350.050
transcription dna templatedGO:00063511810.049
positive regulation of catabolic processGO:000989640.049
spermatid developmentGO:000728620.048
positive regulation of cell cycleGO:004578730.048
positive regulation of cellular catabolic processGO:003133130.048
organonitrogen compound metabolic processGO:1901564740.047
multi organism processGO:00517041340.047
protein targeting to nucleusGO:004474430.047
oocyte maturationGO:000155640.046
protein modification processGO:00362111000.045
chromatin modificationGO:0016568210.045
cellular process involved in reproduction in multicellular organismGO:0022412280.044
multicellular organism growthGO:003526440.044
cellular response to dna damage stimulusGO:0006974240.043
development of primary female sexual characteristicsGO:004654540.043
cellular protein modification processGO:00064641000.043
recombinational repairGO:000072510.042
intracellular mrna localizationGO:000829810.042
regulation of dna replicationGO:000627530.041
intra s dna damage checkpointGO:003157310.041
regulation of metabolic processGO:00192223590.041
double strand break repair via homologous recombinationGO:000072410.041
establishment of protein localization to organelleGO:007259440.041
cellular biosynthetic processGO:00442492860.040
chromosome organization involved in meiosisGO:007019210.040
cell cycleGO:0007049930.040
spindle assembly involved in mitosisGO:009030710.039
sister chromatid cohesionGO:000706220.036
regulation of organelle assemblyGO:190211540.036
regulation of stem cell differentiationGO:200073640.036
purine ribonucleoside monophosphate catabolic processGO:000916940.036
regulation of protein import into nucleusGO:004230620.035
tube morphogenesisGO:00352393490.035
developmental process involved in reproductionGO:0003006270.035
positive regulation of macromolecule metabolic processGO:0010604930.035
cellular response to external stimulusGO:007149620.035
germ cell developmentGO:0007281220.034
negative regulation of dna metabolic processGO:005105340.034
digestive tract morphogenesisGO:00485462310.034
macromolecule modificationGO:00434121110.034
regulation of cellular protein metabolic processGO:0032268520.033
peptidyl serine phosphorylationGO:001810510.033
cellular component biogenesisGO:00440851780.033
nucleocytoplasmic transportGO:000691340.032
multicellular organismal reproductive processGO:0048609350.032
rna metabolic processGO:00160702190.032
deathGO:00162651210.032
dna repairGO:000628160.032
regulation of cellular macromolecule biosynthetic processGO:20001122220.032
regulation of cellular biosynthetic processGO:00313262450.031
positive regulation of gene expressionGO:0010628710.031
nuclear transportGO:005116940.031
regulation of macromolecule metabolic processGO:00602553170.031
negative regulation of dna replicationGO:000815620.031
regulation of protein targetingGO:190353320.031
cell substrate adhesionGO:003158940.031
cell projection organizationGO:00300302840.030
gamete generationGO:0007276330.030
positive regulation of biological processGO:00485182530.030
localization of cellGO:00516742440.029
mitotic cell cycle embryonicGO:004544820.029
heart developmentGO:00075073130.029
anterior posterior pattern specificationGO:00099521520.028
determination of heart left right asymmetryGO:00613711170.028
regulation of nucleobase containing compound metabolic processGO:00192192500.028
response to chemicalGO:00422213200.028
cell part morphogenesisGO:00329902460.028
cell surface receptor signaling pathwayGO:00071663250.028
immune system processGO:00023762410.028
cellular response to starvationGO:000926710.027
atp catabolic processGO:000620040.027
mitotic g2 dna damage checkpointGO:000709530.027
neurological system processGO:0050877620.027
nucleic acid templated transcriptionGO:00976591810.027
phosphorus metabolic processGO:00067931090.027
stem cell maintenanceGO:001982740.027
regulation of signalingGO:00230512350.027
negative regulation of developmental processGO:0051093650.027
regulation of protein catabolic processGO:004217610.027
protein importGO:001703830.027
maternal determination of anterior posterior axis embryoGO:000835840.027
regulation of programmed cell deathGO:00430671010.027
intracellular signal transductionGO:0035556850.026
heterocycle biosynthetic processGO:00181302150.026
cellular macromolecule biosynthetic processGO:00346452240.026
regulation of establishment of protein localizationGO:007020140.025
modification dependent macromolecule catabolic processGO:004363230.025
retina development in camera type eyeGO:00600411460.025
convergent extensionGO:00600261180.025
response to alkaloidGO:004327920.025
response to uvGO:000941130.024
regulation of cell deathGO:00109411030.024
mitotic g2 m transition checkpointGO:004481830.024
purine nucleoside monophosphate catabolic processGO:000912840.024
female meiotic divisionGO:000714320.024
regulation of rna metabolic processGO:00512522240.024
regulation of histone h3 k9 methylationGO:005157020.024
response to stressGO:00069502630.024
nuclear importGO:005117030.024
centrosome cycleGO:000709810.024
modification dependent protein catabolic processGO:001994130.024
regulation of dna metabolic processGO:0051052110.024
regulation of response to stressGO:0080134360.024
system processGO:00030081850.024
ameboidal type cell migrationGO:00016671430.024
female sex differentiationGO:004666040.023
photoreceptor cell differentiationGO:0046530550.023
male meiosisGO:000714020.023
positive regulation of nitrogen compound metabolic processGO:0051173690.023
response to light stimulusGO:0009416460.023
cellular response to stressGO:0033554620.023
multi organism reproductive processGO:0044703360.023
macromolecular complex subunit organizationGO:0043933740.023
positive regulation of dna metabolic processGO:005105410.022
cellular response to chemical stimulusGO:00708871570.022
cellular component assemblyGO:00226071700.022
locomotionGO:00400113130.022
agingGO:000756820.022
protein import into nucleusGO:000660630.022
regulation of primary metabolic processGO:00800903110.022
positive regulation of cellular component biogenesisGO:004408930.022
small molecule metabolic processGO:0044281770.022
covalent chromatin modificationGO:0016569200.021
cellular response to light stimulusGO:007148240.021
reciprocal dna recombinationGO:003582510.021
biosynthetic processGO:00090582940.021
organelle fissionGO:0048285230.021
nucleoside monophosphate catabolic processGO:000912540.021
production of molecular mediator of immune responseGO:000244020.021
regulation of protein complex assemblyGO:004325430.021
cellular component assembly involved in morphogenesisGO:00109271070.021
regulation of cell shapeGO:000836010.020
positive regulation of cytoskeleton organizationGO:005149530.020
internal peptidyl lysine acetylationGO:001839320.020
regulation of multicellular organismal processGO:00512392770.020
positive regulation of protein complex assemblyGO:003133420.020
zymogen activationGO:003163830.020
embryonic organ developmentGO:00485683810.020
regulation of intracellular protein transportGO:003315730.020
regulation of purine nucleotide catabolic processGO:003312120.020
reproductive processGO:0022414400.020
chromatin organizationGO:0006325220.020
positive regulation of rna biosynthetic processGO:1902680570.020
histone h3 k9 modificationGO:006164750.019
cilium or flagellum dependent cell motilityGO:000153940.019
ribonucleoside monophosphate catabolic processGO:000915840.019
developmental programmed cell deathGO:001062340.019
b cell mediated immunityGO:001972430.019
negative regulation of mitosisGO:004583930.019
embryonic heart tube morphogenesisGO:00031431080.019
embryo development ending in birth or egg hatchingGO:00097922710.019
dna templated transcription initiationGO:000635210.019
negative regulation of protein transportGO:005122430.019
sensory perception of smellGO:000760820.019
negative regulation of cellular metabolic processGO:0031324770.019
histone h3 k4 methylationGO:005156820.019
convergent extension involved in gastrulationGO:0060027710.018
cilium movementGO:0003341260.018
positive regulation of nucleic acid templated transcriptionGO:1903508570.018
regulation of protein bindingGO:004339330.018
cellular response to organic substanceGO:00713101050.018
regulation of histone methylationGO:003106030.018
regulation of bindingGO:005109830.018
regulation of molecular functionGO:0065009700.018
regulation of cell communicationGO:00106462320.018
negative regulation of response to stimulusGO:00485851040.018
regulation of cellular amino acid metabolic processGO:000652100.018
regulation of protein ubiquitinationGO:003139630.018
regulation of cytoplasmic transportGO:190364940.018
positive regulation of jnk cascadeGO:004633030.018
regulation of biosynthetic processGO:00098892500.017
regulation of cellular ketone metabolic processGO:001056570.017
organic cyclic compound catabolic processGO:1901361150.017
negative regulation of nucleocytoplasmic transportGO:004682320.017
regulation of anatomical structure morphogenesisGO:00226031300.017
negative regulation of macromolecule metabolic processGO:0010605760.017
female gonad developmentGO:000858540.017
rna localizationGO:000640340.017
negative regulation of programmed cell deathGO:0043069580.017
regulation of signal transductionGO:00099662250.017
sensory perception of chemical stimulusGO:000760630.017
response to oxygen containing compoundGO:1901700550.017
protein acylationGO:004354330.017
regulation of microtubule cytoskeleton organizationGO:007050730.016
protein localization to nucleusGO:003450430.016
negative regulation of chromosome organizationGO:200125110.016
positive regulation of cellular metabolic processGO:0031325940.016
establishment of localization in cellGO:0051649770.016
morphogenesis of an epitheliumGO:00020093330.016
regulation of circadian rhythmGO:004275240.016
regulation of transcription from rna polymerase ii promoterGO:00063571140.016
positive regulation of biosynthetic processGO:0009891680.016
synapsisGO:000712910.016
cell morphogenesis involved in neuron differentiationGO:00486671630.016
negative regulation of metabolic processGO:0009892860.016
digestive tract developmentGO:00485652650.016
negative regulation of cell deathGO:0060548600.016
eye developmentGO:00016542770.016
internal protein amino acid acetylationGO:000647520.016
head developmentGO:00603223030.016
neuron differentiationGO:00301823530.016
reactive oxygen species metabolic processGO:007259360.015
response to drugGO:004249330.015
cellular response to extracellular stimulusGO:003166820.015
camera type eye developmentGO:00430102220.015
cell morphogenesis involved in differentiationGO:00009041950.015
b cell activationGO:004211320.015
cell cycle g1 s phase transitionGO:004484310.015
cellular amine metabolic processGO:004410620.015
cellular response to radiationGO:007147840.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
gastrulationGO:00073692080.015
reproductionGO:0000003400.015
telomere maintenanceGO:000072310.015
lipid catabolic processGO:001604240.015
rna biosynthetic processGO:00327741810.015
response to amphetamineGO:000197510.015
peptidyl serine modificationGO:001820920.015
ribose phosphate metabolic processGO:0019693270.015
regulation of stem cell proliferationGO:007209120.015
determination of bilateral symmetryGO:00098552040.015
gtp catabolic processGO:000618420.014
microtubule cytoskeleton organization involved in mitosisGO:190285010.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
methylationGO:0032259220.014
phagocytosisGO:000690930.014
dna metabolic processGO:0006259270.014
homologous chromosome segregationGO:004514310.014
proteolysis involved in cellular protein catabolic processGO:005160330.014
cell motilityGO:00488702440.014
secondary metabolic processGO:001974830.014
sensory organ morphogenesisGO:00905962000.014
positive regulation of stem cell proliferationGO:200064810.014
regulation of cellular amine metabolic processGO:003323800.014
hepaticobiliary system developmentGO:0061008980.014
cell deathGO:00082191210.014
regulation of dna recombinationGO:000001820.014
guanosine containing compound catabolic processGO:190106920.014
dorsal ventral pattern formationGO:00099531250.014
central nervous system developmentGO:00074173870.014
antimicrobial humoral responseGO:001973020.014
peptidyl lysine acetylationGO:001839420.014
protein acetylationGO:000647320.014
protein complex subunit organizationGO:0071822460.014
cellular nitrogen compound catabolic processGO:0044270150.014
pancreas developmentGO:0031016840.013
single organism nuclear importGO:190259330.013
regulation of cellular protein catabolic processGO:190336210.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
regulation of cell developmentGO:00602841000.013
histone phosphorylationGO:001657220.013
blood vessel morphogenesisGO:00485142160.013
positive regulation of chromatin modificationGO:190331010.013
cellular response to nutrient levelsGO:003166920.013
positive regulation of histone modificationGO:003105810.013
neuron developmentGO:00486662620.013
specification of axis polarityGO:006500140.013
adult behaviorGO:003053420.013
regulation of cysteine type endopeptidase activityGO:2000116210.013
organic acid metabolic processGO:0006082310.013
carbohydrate derivative metabolic processGO:1901135610.013
negative regulation of cell communicationGO:0010648960.013
smooth muscle contractionGO:000693920.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
negative regulation of signalingGO:0023057960.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
organelle assemblyGO:00709251100.013
axis specificationGO:0009798430.013
regulation of cell cycleGO:0051726520.013
mitotic cell cycleGO:0000278640.012
negative regulation of cell cycleGO:0045786140.012
regulation of nucleoside metabolic processGO:000911820.012
translational initiationGO:000641330.012
positive regulation of chromosome organizationGO:200125210.012
spindle assemblyGO:005122520.012
stem cell differentiationGO:00488631170.012
ventricular cardiac muscle tissue morphogenesisGO:005501020.012
regulation of nucleocytoplasmic transportGO:004682220.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
protein alkylationGO:0008213130.012
response to ionizing radiationGO:001021260.012
regulation of transporter activityGO:003240920.012
cell cycle processGO:0022402530.012
regulation of tube sizeGO:003515020.012
regulation of nucleotide catabolic processGO:003081120.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
mitotic cell cycle phase transitionGO:004477290.012
developmental maturationGO:0021700340.012
positive regulation of cellular biosynthetic processGO:0031328680.012
amine metabolic processGO:000930820.012
macroautophagyGO:001623610.012
sex determinationGO:000753010.012
positive regulation of cell divisionGO:005178120.012
histone methylationGO:0016571130.012
stem cell proliferationGO:007208940.012
oocyte anterior posterior axis specificationGO:000731440.012
ubiquitin dependent protein catabolic processGO:000651130.012
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.012
dna methylation or demethylationGO:004472880.012
negative regulation of cellular biosynthetic processGO:0031327550.012
regulation of cell activationGO:005086510.012
positive regulation of transportGO:005105020.012
embryonic digestive tract morphogenesisGO:004855730.012
carboxylic acid metabolic processGO:0019752220.012
establishment of localizationGO:00512342440.012
somatic cell dna recombinationGO:001644410.012
positive regulation of nucleotide catabolic processGO:003081310.012
eye photoreceptor cell developmentGO:0042462300.012
protein stabilizationGO:005082120.012
retina morphogenesis in camera type eyeGO:0060042790.012
melanosome transportGO:0032402190.011
guanosine containing compound metabolic processGO:190106840.011
peptidyl threonine phosphorylationGO:001810710.011
neuron projection morphogenesisGO:00488121610.011
cell cycle arrestGO:000705010.011
protein phosphorylationGO:0006468470.011
regulation of blood pressureGO:000821710.011
dna methylation on cytosineGO:003277630.011
cellular response to oxygen levelsGO:007145310.011
negative regulation of intracellular transportGO:003238730.011
negative regulation of ras protein signal transductionGO:004658010.011
skeletal system developmentGO:00015011810.011
response to external stimulusGO:00096052640.011
tetrapyrrole biosynthetic processGO:003301480.011
positive regulation of macromolecule biosynthetic processGO:0010557590.011
response to endogenous stimulusGO:0009719830.011
cell substrate junction assemblyGO:000704420.011
negative chemotaxisGO:005091910.011
cell migrationGO:00164772370.011
positive regulation of map kinase activityGO:004340630.011
nuclear divisionGO:0000280230.011
regulation of dna catabolic processGO:190362410.011
protein polymerizationGO:005125840.011
response to organic substanceGO:00100331530.011
negative regulation of apoptotic processGO:0043066550.011
anatomical structure arrangementGO:004853220.011
phosphate containing compound metabolic processGO:00067961080.011
periodic partitioningGO:000736510.011
generation of neuronsGO:00486993850.011
negative regulation of protein phosphorylationGO:000193340.011
regulation of cell differentiationGO:00455951420.011
negative regulation of cytoplasmic transportGO:190365020.010
photoreceptor cell developmentGO:0042461400.010
macromolecule methylationGO:0043414190.010
centrosome organizationGO:005129710.010
regulation of reproductive processGO:200024140.010
dna modificationGO:000630480.010
pole plasm assemblyGO:000731540.010
negative regulation of small gtpase mediated signal transductionGO:005105810.010
negative regulation of nuclear divisionGO:005178430.010
cellular amino acid metabolic processGO:000652070.010
regulation of protein localization to nucleusGO:190018020.010
cellular ketone metabolic processGO:0042180110.010
response to monosaccharideGO:003428430.010
peptidyl threonine modificationGO:001821010.010
vacuolar transportGO:000703420.010
mitotic cytokinesisGO:000028130.010

palb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.454
hematopoietic system diseaseDOID:7400.454
disease of anatomical entityDOID:700.454
bone marrow diseaseDOID:496100.363
anemiaDOID:235500.071
fanconi s anemiaDOID:1363600.071
congenital hypoplastic anemiaDOID:134200.071
aplastic anemiaDOID:1244900.071
disease of cellular proliferationDOID:1456600.035
nervous system diseaseDOID:86300.031
cancerDOID:16200.026
disease of metabolismDOID:001466700.021
organ system cancerDOID:005068600.020
inherited metabolic disorderDOID:65500.012