Danio rerio

0 known processes

ryr2a

ryanodine receptor 2a (cardiac)

ryr2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron neuron synaptic transmissionGO:000727010.372
cognitionGO:005089010.301
response to alkaloidGO:004327920.277
monoamine transportGO:001584410.182
adult behaviorGO:003053420.176
regulation of localizationGO:00328791040.174
regulation of camp biosynthetic processGO:003081790.164
lipid catabolic processGO:001604240.155
positive regulation of camp biosynthetic processGO:003081920.146
ion transmembrane transportGO:0034220910.140
ion transportGO:00068111140.139
circadian sleep wake cycle processGO:002241020.138
muscle cell developmentGO:00550011150.125
regulation of cyclase activityGO:0031279120.123
sleepGO:003043110.120
circadian sleep wake cycle sleepGO:005080210.108
single organism localizationGO:19025782250.106
positive regulation of camp metabolic processGO:003081620.105
nucleobase containing compound biosynthetic processGO:00346542050.104
response to amphetamineGO:000197510.095
regulation of tube sizeGO:003515020.090
regulation of adenylate cyclase activityGO:004576160.089
maintenance of locationGO:005123540.089
regenerationGO:0031099910.088
regulation of circadian sleep wake cycleGO:004274910.087
regulation of dendrite developmentGO:005077330.085
regulation of synaptic plasticityGO:004816710.082
transmembrane transportGO:00550851200.079
regulation of ion transmembrane transporter activityGO:003241220.078
embryonic organ developmentGO:00485683810.078
response to external stimulusGO:00096052640.076
circadian sleep wake cycleGO:004274520.072
cellular lipid catabolic processGO:004424230.070
central nervous system developmentGO:00074173870.070
response to drugGO:004249330.070
wound healingGO:0042060900.069
larval developmentGO:000216420.069
positive regulation of transportGO:005105020.068
response to woundingGO:00096111160.067
regulation of transmembrane transportGO:0034762180.065
regulation of blood pressureGO:000821710.064
cation transportGO:0006812810.064
regulation of erk1 and erk2 cascadeGO:007037240.061
embryo development ending in birth or egg hatchingGO:00097922710.061
regulation of postsynaptic membrane potentialGO:006007810.061
agingGO:000756820.058
response to stressGO:00069502630.058
growthGO:00400071740.055
hormone transportGO:000991420.054
response to carbohydrateGO:000974330.052
erk1 and erk2 cascadeGO:007037140.052
positive regulation of cell cycleGO:004578730.052
nucleobase containing compound metabolic processGO:00061392740.051
cyclic nucleotide biosynthetic processGO:0009190180.050
nuclear migrationGO:000709730.050
camp biosynthetic processGO:0006171110.050
developmental growthGO:00485891660.050
regulation of ion transmembrane transportGO:0034765180.049
response to amineGO:001407510.048
regulation of developmental processGO:00507932470.048
muscle organ developmentGO:00075171010.048
regulation of biological qualityGO:00650082630.047
cellular protein catabolic processGO:004425740.047
regulation of circadian rhythmGO:004275240.046
cation transmembrane transportGO:0098655650.045
golgi vesicle transportGO:004819330.045
sensory perception of painGO:001923310.045
negative regulation of protein phosphorylationGO:000193340.045
negative regulation of protein kinase activityGO:000646940.045
cellular component biogenesisGO:00440851780.045
hormone secretionGO:004687920.044
regulation of protein transportGO:005122330.044
response to nicotineGO:003509420.043
embryonic organ morphogenesisGO:00485622740.042
glucose homeostasisGO:004259310.042
tube morphogenesisGO:00352393490.042
multicellular organism growthGO:003526440.041
regulation of response to stimulusGO:00485832690.041
regulation of receptor activityGO:001046920.041
protein secretionGO:000930610.040
regulation of circadian sleep wake cycle sleepGO:004518710.040
morphogenesis of an epitheliumGO:00020093330.040
cellular component maintenanceGO:004395430.039
regulation of cyclic nucleotide biosynthetic processGO:0030802150.039
peptidyl serine phosphorylationGO:001810510.039
regulation of metal ion transportGO:001095940.038
regulation of multicellular organismal developmentGO:20000262230.038
regulation of calcium ion transportGO:005192420.038
modification dependent protein catabolic processGO:001994130.038
regulation of cellular biosynthetic processGO:00313262450.037
negative regulation of hormone secretionGO:004688820.037
synaptic growth at neuromuscular junctionGO:005112420.037
generation of neuronsGO:00486993850.037
positive regulation of secretionGO:005104710.037
regulation of cell communicationGO:00106462320.036
positive regulation of cellular component biogenesisGO:004408930.036
postsynaptic membrane organizationGO:000194130.036
regulation of reproductive processGO:200024140.036
regulation of transmembrane transporter activityGO:002289820.036
regulation of neurological system processGO:003164420.036
synaptic transmission cholinergicGO:000727140.036
heart developmentGO:00075073130.035
striated muscle cell developmentGO:00550021080.035
regulation of protein modification by small protein conjugation or removalGO:190332030.035
response to chemicalGO:00422213200.035
cellular response to oxygen levelsGO:007145310.035
cellular amine metabolic processGO:004410620.035
organic cyclic compound metabolic processGO:19013603010.034
transportGO:00068102200.034
cyclic purine nucleotide metabolic processGO:0052652180.034
regulation of endocrine processGO:004406020.034
neuron differentiationGO:00301823530.033
cellular component assemblyGO:00226071700.033
regulation of cytokine productionGO:000181730.033
heart contractionGO:0060047710.033
macromolecule biosynthetic processGO:00090592270.033
organelle assemblyGO:00709251100.033
small molecule catabolic processGO:004428230.033
positive regulation of secretion by cellGO:190353210.033
blood circulationGO:0008015870.033
cellular component morphogenesisGO:00329893360.033
actin mediated cell contractionGO:007025210.032
cell migrationGO:00164772370.032
aromatic compound biosynthetic processGO:00194382170.032
regulation of transporter activityGO:003240920.032
regulation of cellular component organizationGO:0051128860.031
smooth muscle contractionGO:000693920.031
regulation of blood vessel sizeGO:005088020.031
regulation of establishment of protein localizationGO:007020140.031
regulation of dendrite morphogenesisGO:004881430.031
heterocycle biosynthetic processGO:00181302150.031
neurological system processGO:0050877620.031
cell substrate adhesionGO:003158940.031
synaptic transmissionGO:0007268350.031
establishment of localizationGO:00512342440.031
regulation of neuronal synaptic plasticityGO:004816810.031
response to amino acidGO:004320020.031
regulation of hormone secretionGO:004688320.030
cellular response to decreased oxygen levelsGO:003629410.030
response to monosaccharideGO:003428430.030
sensory perception of smellGO:000760820.030
multi organism processGO:00517041340.030
regulation of camp metabolic processGO:003081490.030
cytokinesisGO:000091030.030
positive regulation of lyase activityGO:005134960.030
small molecule metabolic processGO:0044281770.030
neuron projection developmentGO:00311751800.030
regulation of synapse organizationGO:005080730.030
endocrine processGO:005088620.029
mechanosensory behaviorGO:000763820.029
regulation of protein localization to nucleusGO:190018020.028
sensory organ developmentGO:00074233930.028
calcium ion importGO:007050940.028
myofibril assemblyGO:0030239480.028
response to immobilization stressGO:003590210.028
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.027
meiotic nuclear divisionGO:000712640.027
development of primary female sexual characteristicsGO:004654540.027
regulation of synaptic growth at neuromuscular junctionGO:000858210.027
ubiquitin dependent protein catabolic processGO:000651130.027
sodium ion transportGO:0006814240.027
nitrogen compound metabolic processGO:00068073190.027
cellular component movementGO:00069283350.026
tissue regenerationGO:0042246740.026
organonitrogen compound metabolic processGO:1901564740.026
muscle structure developmentGO:00610611960.026
brain developmentGO:00074202930.026
regulation of cellular macromolecule biosynthetic processGO:20001122220.026
locomotory behaviorGO:0007626340.026
positive regulation of erk1 and erk2 cascadeGO:007037420.026
cellular monovalent inorganic cation homeostasisGO:003000420.025
regulation of cytoplasmic transportGO:190364940.025
sequestering of metal ionGO:005123830.025
determination of bilateral symmetryGO:00098552040.025
regulation of locomotionGO:0040012550.025
phagocytosisGO:000690930.025
growth plate cartilage morphogenesisGO:000342210.025
pronuclear migrationGO:003504610.025
cellular localizationGO:0051641970.024
regulation of wound healingGO:006104120.024
protein modification processGO:00362111000.024
regulation of nucleobase containing compound metabolic processGO:00192192500.024
negative regulation of protein transportGO:005122430.024
response to lipidGO:0033993600.024
response to steroid hormoneGO:0048545350.024
eye morphogenesisGO:00485921440.024
primary neural tube formationGO:001402010.024
dendrite guidanceGO:007098300.024
sodium ion transmembrane transportGO:0035725210.024
regulation of nucleotide biosynthetic processGO:0030808150.024
cellular response to biotic stimulusGO:007121630.024
muscle cell differentiationGO:00426921390.024
calcium ion transportGO:0006816180.023
melanosome localizationGO:0032400210.023
sensory organ morphogenesisGO:00905962000.023
response to bacteriumGO:0009617580.023
dicarboxylic acid transportGO:000683510.023
cell motilityGO:00488702440.023
response to organic substanceGO:00100331530.023
positive regulation of neuron apoptotic processGO:004352510.023
endocrine hormone secretionGO:006098620.023
regulation of transportGO:0051049450.023
regulation of ion transportGO:0043269220.023
regulation of cell shapeGO:000836010.023
reproductive processGO:0022414400.022
modification dependent macromolecule catabolic processGO:004363230.022
single organism transportGO:00447652060.022
nucleic acid metabolic processGO:00903042440.022
nitrogen compound transportGO:0071705230.022
inorganic ion transmembrane transportGO:0098660570.022
centrosome organizationGO:005129710.022
regulation of cellular metabolic processGO:00313233200.022
cellular macromolecule metabolic processGO:00442603910.022
rna metabolic processGO:00160702190.022
chemosensory behaviorGO:000763510.022
response to nitrogen compoundGO:1901698190.022
rna biosynthetic processGO:00327741810.022
cell morphogenesis involved in neuron differentiationGO:00486671630.022
homeostatic processGO:00425921420.022
response to glucocorticoidGO:005138410.022
female sex differentiationGO:004666040.021
regulation of synapse assemblyGO:005196330.021
phosphorus metabolic processGO:00067931090.021
response to glucoseGO:000974930.021
calcium mediated signalingGO:001972220.021
negative regulation of kinase activityGO:003367340.021
medulla oblongata developmentGO:002155040.021
regulation of molecular functionGO:0065009700.021
regulation of lyase activityGO:0051339120.021
organonitrogen compound biosynthetic processGO:1901566470.021
cellular biosynthetic processGO:00442492860.021
fat soluble vitamin metabolic processGO:000677540.021
calcium ion transport into cytosolGO:006040230.021
epithelial tube morphogenesisGO:00605621480.021
neuromuscular synaptic transmissionGO:000727420.021
amine metabolic processGO:000930820.021
cellular aromatic compound metabolic processGO:00067252950.021
protein import into nucleusGO:000660630.020
regulation of signalingGO:00230512350.020
regulation of protein ubiquitinationGO:003139630.020
growth plate cartilage developmentGO:000341720.020
regulation of cell developmentGO:00602841000.020
pigment granule localizationGO:0051875250.020
regulation of neurogenesisGO:0050767870.020
g protein coupled receptor signaling pathwayGO:0007186740.020
extrinsic apoptotic signaling pathwayGO:009719130.020
regulation of cellular amine metabolic processGO:003323800.020
response to endogenous stimulusGO:0009719830.019
nucleotide biosynthetic processGO:0009165210.019
response to nutrientGO:000758430.019
regulation of cellular protein metabolic processGO:0032268520.019
regulation of nitrogen compound metabolic processGO:00511712510.019
transcription from rna polymerase ii promoterGO:0006366800.019
localization of cellGO:00516742440.019
carbohydrate derivative biosynthetic processGO:1901137430.019
negative regulation of secretion by cellGO:190353120.019
response to foodGO:003209410.019
mitochondrion organizationGO:000700540.019
actin cytoskeleton organizationGO:0030036630.019
regulation of macromolecule metabolic processGO:00602553170.019
circulatory system processGO:0003013870.019
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
organic acid metabolic processGO:0006082310.019
synapse organizationGO:0050808210.018
central nervous system neuron differentiationGO:0021953740.018
regulation of embryonic developmentGO:0045995470.018
female gonad developmentGO:000858540.018
positive regulation of cell adhesionGO:004578510.018
regulation of n methyl d aspartate selective glutamate receptor activityGO:200031010.018
cellular ketone metabolic processGO:0042180110.018
heterocycle metabolic processGO:00464832900.018
regulation of multicellular organismal processGO:00512392770.018
regulation of phGO:000688530.018
positive regulation of inflammatory responseGO:005072910.018
cell surface receptor signaling pathwayGO:00071663250.018
detection of temperature stimulusGO:001604800.018
post embryonic morphogenesisGO:000988640.018
regulation of anatomical structure morphogenesisGO:00226031300.018
developmental growth involved in morphogenesisGO:0060560860.018
endocrine system developmentGO:0035270650.018
symbiosis encompassing mutualism through parasitismGO:004440340.018
microtubule organizing center organizationGO:003102310.017
positive regulation of response to stimulusGO:0048584800.017
biosynthetic processGO:00090582940.017
proteasomal protein catabolic processGO:001049820.017
cell matrix adhesionGO:000716040.017
negative regulation of metabolic processGO:0009892860.017
head developmentGO:00603223030.017
cellular response to hypoxiaGO:007145610.017
negative regulation of sequestering of calcium ionGO:005128340.017
gene expressionGO:00104672520.017
axon guidanceGO:0007411860.017
peptide transportGO:001583310.017
cell part morphogenesisGO:00329902460.017
cellular component assembly involved in morphogenesisGO:00109271070.017
membrane hyperpolarizationGO:006008110.017
response to organic cyclic compoundGO:0014070510.017
steroid hormone secretionGO:003592910.017
regulation of bindingGO:005109830.017
negative regulation of biological processGO:00485193040.016
positive regulation of cellular processGO:00485222010.016
proteolysis involved in cellular protein catabolic processGO:005160330.016
inner ear developmentGO:00488391260.016
actomyosin structure organizationGO:0031032530.016
system processGO:00030081850.016
aorta morphogenesisGO:003590930.016
metal ion transportGO:0030001580.016
purine ribonucleoside monophosphate catabolic processGO:000916940.016
regulation of metabolic processGO:00192223590.016
purine nucleotide biosynthetic processGO:0006164200.016
regulation of rna metabolic processGO:00512522240.016
lipid storageGO:001991510.016
positive regulation of apoptotic signaling pathwayGO:200123510.016
determination of heart left right asymmetryGO:00613711170.016
positive regulation of biological processGO:00485182530.016
regulation of steroid hormone secretionGO:200083110.016
appendage morphogenesisGO:0035107560.016
establishment of protein localization to organelleGO:007259440.016
regulation of glutamate receptor signaling pathwayGO:190044910.016
positive regulation of catabolic processGO:000989640.016
cellular response to chemical stimulusGO:00708871570.016
regulation of protein catabolic processGO:004217610.015
axonogenesisGO:00074091520.015
organic hydroxy compound biosynthetic processGO:190161760.015
response to activityGO:0014823140.015
regulation of systemic arterial blood pressureGO:000307310.015
endochondral bone growthGO:000341620.015
cellular response to endogenous stimulusGO:0071495680.015
pigmentationGO:0043473850.015
regulation of programmed cell deathGO:00430671010.015
negative regulation of macromolecule metabolic processGO:0010605760.015
regulation of protein metabolic processGO:0051246560.015
positive regulation of ras protein signal transductionGO:004657910.015
hindbrain developmentGO:0030902910.015
neuron developmentGO:00486662620.015
protein localization to nucleusGO:003450430.015
cellular protein metabolic processGO:00442671290.015
positive regulation of leukocyte differentiationGO:190210710.015
protein metabolic processGO:00195381830.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
response to hexoseGO:000974630.015
regulation of cell differentiationGO:00455951420.015
negative regulation of catabolic processGO:000989530.015
nucleic acid templated transcriptionGO:00976591810.015
response to estrogenGO:0043627270.015
cellular nitrogen compound metabolic processGO:00346412900.015
regulation of microtubule cytoskeleton organizationGO:007050730.014
actin filament based processGO:0030029640.014
purine ribonucleotide biosynthetic processGO:0009152200.014
glucose importGO:004632320.014
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.014
monovalent inorganic cation transportGO:0015672420.014
response to ketoneGO:190165410.014
carbohydrate homeostasisGO:003350010.014
regulation of membrane potentialGO:0042391230.014
cellular amino acid metabolic processGO:000652070.014
actin filament based movementGO:003004810.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
positive regulation of cell communicationGO:0010647560.014
regulation of system processGO:0044057400.014
cellular carbohydrate metabolic processGO:004426240.014
eye developmentGO:00016542770.014
signal transductionGO:00071654550.014
organic substance transportGO:0071702580.014
regulation of nucleocytoplasmic transportGO:004682220.014
response to oxygen containing compoundGO:1901700550.014
regulation of glucose importGO:004632410.014
oligopeptide transportGO:000685710.014
positive regulation of cytokine productionGO:000181920.014
phosphate containing compound metabolic processGO:00067961080.014
nucleocytoplasmic transportGO:000691340.014
single organism biosynthetic processGO:0044711710.014
compound eye developmentGO:004874920.014
post embryonic organ morphogenesisGO:004856310.014
regulation of protein complex assemblyGO:004325430.014
single organism organelle organizationGO:19025891990.014
positive regulation of cellular amine metabolic processGO:003324000.014
inorganic cation transmembrane transportGO:0098662500.014
nuclear importGO:005117030.014
organophosphate biosynthetic processGO:0090407230.014
intracellular estrogen receptor signaling pathwayGO:003052030.014
regulation of intracellular protein transportGO:003315730.013
guanosine containing compound metabolic processGO:190106840.013
taxisGO:00423301090.013
negative regulation of nucleobase containing compound metabolic processGO:0045934590.013
otolith formationGO:003247520.013
organism emergence from protective structureGO:007168440.013
nuclear transportGO:005116940.013
skeletal system developmentGO:00015011810.013
regulation of biosynthetic processGO:00098892500.013
transcription dna templatedGO:00063511810.013
cytosolic calcium ion transportGO:006040130.013
behaviorGO:0007610740.013
cellular response to radiationGO:007147840.013
melanin metabolic processGO:000658220.013
protein localization to membraneGO:007265790.013
regulation of gene expressionGO:00104682650.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
regulation of myotube differentiationGO:001083020.013
cell projection morphogenesisGO:00488582440.013
dorsal ventral pattern formationGO:00099531250.013
response to mechanical stimulusGO:0009612240.013
regulation of intracellular phGO:005145310.013
ras protein signal transductionGO:000726570.013
fin developmentGO:0033333770.013
sodium ion importGO:009736930.012
oxoacid metabolic processGO:0043436310.012
centrosome cycleGO:000709810.012
embryonic skeletal system developmentGO:0048706970.012
positive regulation of synapse assemblyGO:005196510.012
digestive system developmentGO:00551232890.012
regulation of cell migration involved in sprouting angiogenesisGO:009004930.012
single organism behaviorGO:0044708240.012
organic cyclic compound biosynthetic processGO:19013622230.012
regulation of cellular protein catabolic processGO:190336210.012
response to hypoxiaGO:0001666250.012
regulation of signal transductionGO:00099662250.012
regulation of retinoic acid receptor signaling pathwayGO:004838550.012
thermosensory behaviorGO:004004010.012
protein localization to plasma membraneGO:007265910.012
gtp catabolic processGO:000618420.012
mechanosensory lateral line system developmentGO:0048881490.012
regulation of stem cell differentiationGO:200073640.012
single fertilizationGO:000733830.012
chemotaxisGO:00069351040.012
regulation of cellular amino acid metabolic processGO:000652100.012
cell projection organizationGO:00300302840.012
negative regulation of behaviorGO:004852160.012
ear developmentGO:00435831270.011
regulation of primary metabolic processGO:00800903110.011
regulation of multicellular organism growthGO:004001440.011
negative regulation of cellular protein metabolic processGO:0032269160.011
gonadotropin secretionGO:003227410.011
regulation of cell deathGO:00109411030.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
negative regulation of multi organism processGO:004390130.011
regulation of cyclic nucleotide metabolic processGO:0030799150.011
positive regulation of wound healingGO:009030310.011
cellular macromolecule biosynthetic processGO:00346452240.011
establishment of localization in cellGO:0051649770.011
negative regulation of programmed cell deathGO:0043069580.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
calcium ion transmembrane transportGO:0070588130.011
positive regulation of developmental processGO:0051094500.011
intracellular mrna localizationGO:000829810.011
phosphorylationGO:0016310690.011
positive regulation of cell deathGO:0010942290.011
membrane organizationGO:0061024210.011
cytoskeleton organizationGO:0007010960.011
cyclic nucleotide metabolic processGO:0009187180.011
negative regulation of cellular metabolic processGO:0031324770.011
angiogenesisGO:00015251580.011
regulation of cellular ketone metabolic processGO:001056570.011
neurotransmitter secretionGO:000726920.011
phagocytosis engulfmentGO:000691110.011
response to hormoneGO:0009725480.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
ion homeostasisGO:0050801410.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:000718750.011
synaptic vesicle transportGO:004848910.011
regulation of inflammatory responseGO:005072720.011
cell proliferationGO:0008283800.011
negative regulation of cellular processGO:00485232830.011
ribonucleotide biosynthetic processGO:0009260200.011
negative regulation of gene expressionGO:0010629650.011
regulation of phosphate metabolic processGO:0019220430.011
regulation of nucleic acid templated transcriptionGO:19035062130.011
fatty acid transportGO:001590810.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
positive regulation of purine nucleotide biosynthetic processGO:190037380.011
response to vitamin b3GO:003355220.011
carboxylic acid metabolic processGO:0019752220.010
secondary metabolic processGO:001974830.010
regulation of blood circulationGO:1903522320.010
regulation of phosphorylationGO:0042325260.010
exocytosisGO:000688710.010
nuclear exportGO:005116810.010
release of sequestered calcium ion into cytosolGO:005120930.010
epithelial cilium movement involved in determination of left right asymmetryGO:006028780.010
detection of temperature stimulus involved in sensory perceptionGO:005096100.010
macromolecule localizationGO:0033036540.010
regulation of glucose transportGO:001082710.010
establishment of synaptic vesicle localizationGO:009748010.010
cell deathGO:00082191210.010
posterior lateral line developmentGO:0048916380.010
hematopoietic or lymphoid organ developmentGO:00485341910.010
cellular response to steroid hormone stimulusGO:0071383310.010
multicellular organismal reproductive processGO:0048609350.010
regulation of protein import into nucleusGO:004230620.010
monocarboxylic acid catabolic processGO:007232930.010
negative regulation of secretionGO:005104820.010
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.010

ryr2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
cardiovascular system diseaseDOID:128700.025
disease of cellular proliferationDOID:1456600.018
organ system cancerDOID:005068600.018
cancerDOID:16200.018
nervous system diseaseDOID:86300.011