Danio rerio

0 known processes

tph1b

tryptophan hydroxylase 1b

(Aliases: tph2,tph1l,tphD2)

tph1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
convergent extensionGO:00600261180.337
developmental growth involved in morphogenesisGO:0060560860.233
cell morphogenesis involved in neuron differentiationGO:00486671630.232
axon developmentGO:00615641660.208
cellular component movementGO:00069283350.191
regulation of axonogenesisGO:0050770320.180
organic cyclic compound metabolic processGO:19013603010.168
Zebrafish Worm Fly
neuron developmentGO:00486662620.158
axonogenesisGO:00074091520.147
ubiquitin dependent protein catabolic processGO:000651130.142
transportGO:00068102200.128
adult behaviorGO:003053420.126
modification dependent protein catabolic processGO:001994130.120
cellular biosynthetic processGO:00442492860.119
Zebrafish Worm Fly
gastrulationGO:00073692080.117
central nervous system developmentGO:00074173870.106
Zebrafish
small molecule metabolic processGO:0044281770.105
Worm
regulation of response to stimulusGO:00485832690.105
Worm Fly
heterocycle metabolic processGO:00464832900.104
Zebrafish Worm Fly
taxisGO:00423301090.100
cell surface receptor signaling pathwayGO:00071663250.099
Worm
axon extensionGO:0048675450.096
nitrogen compound metabolic processGO:00068073190.096
Zebrafish Worm Fly
proteolysis involved in cellular protein catabolic processGO:005160330.096
cell growthGO:0016049570.092
embryonic organ developmentGO:00485683810.092
determination of heart left right asymmetryGO:00613711170.092
embryo development ending in birth or egg hatchingGO:00097922710.091
Worm
regulation of axon extensionGO:0030516240.088
blood vessel developmentGO:00015682460.087
signal transductionGO:00071654550.085
Worm
mesenchymal cell differentiationGO:0048762870.085
single organism transportGO:00447652060.083
nucleocytoplasmic transportGO:000691340.081
cell migrationGO:00164772370.080
response to organic substanceGO:00100331530.080
Zebrafish Worm
developmental cell growthGO:0048588520.079
oocyte maturationGO:000155640.079
cellular nitrogen compound metabolic processGO:00346412900.079
Zebrafish Worm Fly
locomotionGO:00400113130.078
cell motilityGO:00488702440.077
head developmentGO:00603223030.077
cell morphogenesis involved in differentiationGO:00009041950.077
cellular aromatic compound metabolic processGO:00067252950.075
Zebrafish Worm Fly
ameboidal type cell migrationGO:00016671430.074
agingGO:000756820.074
Worm
cellular component assemblyGO:00226071700.073
ion transmembrane transportGO:0034220910.072
heterocycle biosynthetic processGO:00181302150.071
Zebrafish Worm Fly
muscle structure developmentGO:00610611960.071
cation transportGO:0006812810.070
negative regulation of biological processGO:00485193040.069
neuron projection extensionGO:1990138450.069
cell projection organizationGO:00300302840.068
regulation of cell communicationGO:00106462320.068
Worm
localization of cellGO:00516742440.067
cation transmembrane transportGO:0098655650.065
regulation of localizationGO:00328791040.064
growthGO:00400071740.064
regulation of reproductive processGO:200024140.064
Worm
morphogenesis of an epithelial foldGO:006057110.063
angiogenesisGO:00015251580.062
cell projection morphogenesisGO:00488582440.061
regulation of cellular metabolic processGO:00313233200.061
phagocytosisGO:000690930.061
organic substance catabolic processGO:1901575280.061
organic acid metabolic processGO:0006082310.060
Worm
digestive tract morphogenesisGO:00485462310.060
regulation of multicellular organismal developmentGO:20000262230.060
proteasomal protein catabolic processGO:001049820.059
epibolyGO:0090504410.059
negative regulation of cell communicationGO:0010648960.058
developmental growthGO:00485891660.056
chemotaxisGO:00069351040.056
regulation of metabolic processGO:00192223590.056
multi organism reproductive processGO:0044703360.055
Worm
multi organism processGO:00517041340.055
Worm
negative regulation of protein phosphorylationGO:000193340.053
wnt signaling pathwayGO:0016055800.053
regulation of extent of cell growthGO:0061387290.053
morphogenesis of an epitheliumGO:00020093330.053
regulation of jun kinase activityGO:004350630.052
modification dependent macromolecule catabolic processGO:004363230.052
cell part morphogenesisGO:00329902460.051
ion transportGO:00068111140.050
neuromuscular synaptic transmissionGO:000727420.050
regulation of multicellular organismal processGO:00512392770.049
Worm Fly
cellular protein catabolic processGO:004425740.049
response to chemicalGO:00422213200.048
Zebrafish Worm
neuron projection developmentGO:00311751800.048
single organism behaviorGO:0044708240.048
Fly
blood vessel morphogenesisGO:00485142160.048
neuron projection guidanceGO:0097485860.048
response to external stimulusGO:00096052640.047
regulation of nucleobase containing compound metabolic processGO:00192192500.047
regulation of protein complex assemblyGO:004325430.047
generation of neuronsGO:00486993850.047
Zebrafish
enzyme linked receptor protein signaling pathwayGO:00071671060.047
Worm
regulation of primary metabolic processGO:00800903110.045
somatic muscle developmentGO:000752540.044
macromolecule biosynthetic processGO:00090592270.044
single organism localizationGO:19025782250.044
immune system developmentGO:00025201910.044
determination of left right symmetryGO:00073681790.043
apoptotic processGO:00069151160.042
positive regulation of catabolic processGO:000989640.042
hepaticobiliary system developmentGO:0061008980.041
vasculature developmentGO:00019442780.041
phosphate containing compound metabolic processGO:00067961080.040
regulation of cell growthGO:0001558290.039
nuclear transportGO:005116940.039
regulation of nucleoside metabolic processGO:000911820.039
regulation of neuron projection developmentGO:0010975400.039
female sex differentiationGO:004666040.039
response to endogenous stimulusGO:0009719830.038
Zebrafish Worm
axon guidanceGO:0007411860.038
regulation of protein import into nucleusGO:004230620.038
morphogenesis of an epithelial sheetGO:0002011490.038
regulation of developmental processGO:00507932470.037
Mouse
negative regulation of cellular processGO:00485232830.037
regulation of cellular component organizationGO:0051128860.037
digestive system developmentGO:00551232890.037
transmembrane transportGO:00550851200.036
regulation of cell morphogenesisGO:0022604420.036
larval developmentGO:000216420.036
Worm
specification of symmetryGO:00097992040.036
neuron projection morphogenesisGO:00488121610.036
eye field cell fate commitment involved in camera type eye formationGO:006089830.036
metal ion transportGO:0030001580.035
stem cell proliferationGO:007208940.035
response to stressGO:00069502630.035
regulation of nitrogen compound metabolic processGO:00511712510.034
segmentationGO:0035282970.034
phosphorus metabolic processGO:00067931090.034
brain developmentGO:00074202930.034
protein targeting to nucleusGO:004474430.034
secondary metabolic processGO:001974830.034
regulation of biological qualityGO:00650082630.033
Worm
regulation of cell projection organizationGO:0031344440.033
regulation of protein catabolic processGO:004217610.033
nucleobase containing compound metabolic processGO:00061392740.033
gtp catabolic processGO:000618420.033
regulation of anatomical structure morphogenesisGO:00226031300.032
tube morphogenesisGO:00352393490.032
cell migration involved in gastrulationGO:0042074790.032
eye developmentGO:00016542770.032
homeostatic processGO:00425921420.032
organic cyclic compound biosynthetic processGO:19013622230.031
Zebrafish Worm Fly
cellular amine metabolic processGO:004410620.031
Worm
regulation of cell sizeGO:0008361290.031
cellular response to organic substanceGO:00713101050.031
Zebrafish Worm
regulation of cellular component movementGO:0051270550.030
negative regulation of protein complex assemblyGO:003133310.030
negative regulation of signalingGO:0023057960.030
positive regulation of cellular catabolic processGO:003133130.030
retinal ganglion cell axon guidanceGO:0031290350.030
regulation of ion transmembrane transporter activityGO:003241220.029
protein importGO:001703830.029
forebrain developmentGO:0030900960.029
programmed cell deathGO:00125011190.029
muscle cell differentiationGO:00426921390.028
regulation of gene expressionGO:00104682650.028
regionalizationGO:00030022740.028
optic placode formation involved in camera type eye formationGO:004661930.028
cell cell recognitionGO:000998810.027
organonitrogen compound metabolic processGO:1901564740.027
Zebrafish Worm Fly
cellular component morphogenesisGO:00329893360.027
kupffer s vesicle developmentGO:0070121500.026
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
regulation of cellular macromolecule biosynthetic processGO:20001122220.026
membrane repolarizationGO:008600920.026
regulation of apoptotic processGO:0042981980.026
regulation of protein localization to nucleusGO:190018020.026
biosynthetic processGO:00090582940.026
Zebrafish Worm Fly
establishment of protein localization to organelleGO:007259440.025
regulation of protein targetingGO:190353320.025
muscle system processGO:0003012200.025
immune system processGO:00023762410.025
regulation of nucleotide catabolic processGO:003081120.025
alpha amino acid metabolic processGO:190160530.025
Worm
regulation of nucleocytoplasmic transportGO:004682220.025
gene expressionGO:00104672520.025
regulation of cellular biosynthetic processGO:00313262450.024
gastrulation with mouth forming secondGO:0001702440.024
swim bladder developmentGO:0048794190.024
carboxylic acid metabolic processGO:0019752220.024
Worm
mitochondrion organizationGO:000700540.024
determination of bilateral symmetryGO:00098552040.024
deathGO:00162651210.024
negative regulation of response to stimulusGO:00485851040.024
stem cell developmentGO:0048864820.024
nucleic acid metabolic processGO:00903042440.023
regulation of metal ion transportGO:001095940.023
mesenchymal cell developmentGO:0014031780.023
cellular response to endogenous stimulusGO:0071495680.023
Zebrafish Worm
digestive tract developmentGO:00485652650.023
cell deathGO:00082191210.023
cellular response to external stimulusGO:007149620.023
heart loopingGO:0001947940.023
regulation of cell motilityGO:2000145460.023
determination of dorsal ventral asymmetryGO:0048262340.023
sensory perception of chemical stimulusGO:000760630.022
regulation of bindingGO:005109830.022
protein import into nucleusGO:000660630.022
organic substance biosynthetic processGO:19015762890.022
Zebrafish Worm Fly
cellular carbohydrate metabolic processGO:004426240.022
cytosolic calcium ion transportGO:006040130.022
negative regulation of macromolecule metabolic processGO:0010605760.022
regulation of signal transductionGO:00099662250.022
Worm
regulation of purine nucleotide catabolic processGO:003312120.022
meiotic nuclear divisionGO:000712640.021
hematopoietic or lymphoid organ developmentGO:00485341910.021
establishment of localizationGO:00512342440.021
cellular macromolecule biosynthetic processGO:00346452240.021
regulation of cell migrationGO:0030334400.021
cellular nitrogen compound biosynthetic processGO:00442712180.021
Zebrafish Worm Fly
regulation of cytokine productionGO:000181730.021
macromolecule modificationGO:00434121110.021
rna metabolic processGO:00160702190.020
connective tissue developmentGO:0061448990.020
protein localization to nucleusGO:003450430.020
negative regulation of signal transductionGO:0009968940.020
single organism metabolic processGO:00447102170.020
Zebrafish Mouse Worm Fly
somite developmentGO:0061053960.020
skeletal muscle organ developmentGO:0060538780.020
cellular macromolecule metabolic processGO:00442603910.020
negative regulation of protein localization to nucleusGO:190018120.020
convergent extension involved in gastrulationGO:0060027710.020
neural crest cell migrationGO:0001755420.020
cellular response to chemical stimulusGO:00708871570.020
Zebrafish Worm
amine metabolic processGO:000930820.020
Worm
cellular component biogenesisGO:00440851780.020
response to carbohydrateGO:000974330.019
regulation of signalingGO:00230512350.019
Worm
optic placode formationGO:000174340.019
cartilage developmentGO:0051216960.019
aromatic compound biosynthetic processGO:00194382170.019
Zebrafish Worm Fly
neuroblast proliferationGO:000740520.019
regulation of rna metabolic processGO:00512522240.019
maintenance of locationGO:005123540.019
Worm
regulation of rna biosynthetic processGO:20011412130.019
regulation of intracellular protein transportGO:003315730.019
regulation of synaptic plasticityGO:004816710.019
inorganic cation transmembrane transportGO:0098662500.019
embryonic digestive tract morphogenesisGO:004855730.019
gtp metabolic processGO:004603940.018
dopamine metabolic processGO:004241720.018
Zebrafish
regulation of neuron differentiationGO:0045664560.018
regulation of cell differentiationGO:00455951420.018
Mouse
embryonic heart tube developmentGO:00350501330.018
epiboly involved in gastrulation with mouth forming secondGO:0055113350.018
nerve developmentGO:0021675450.018
striated muscle cell differentiationGO:00511461290.018
regulation of cellular component sizeGO:0032535300.018
regenerationGO:0031099910.018
negative regulation of cell deathGO:0060548600.018
negative regulation of nuclear divisionGO:005178430.018
negative regulation of metabolic processGO:0009892860.018
guanosine containing compound metabolic processGO:190106840.018
negative regulation of mitosisGO:004583930.018
development of primary female sexual characteristicsGO:004654540.018
response to abiotic stimulusGO:00096281220.017
regulation of organ growthGO:004662030.017
spemann organizer formationGO:0060061100.017
cell morphogenesisGO:00009022890.017
stem cell maintenanceGO:001982740.017
negative regulation of cellular component organizationGO:0051129160.017
cellular cation homeostasisGO:0030003170.017
positive regulation of jun kinase activityGO:004350720.017
pathway restricted smad protein phosphorylationGO:006038910.017
positive regulation of translationGO:004572710.017
cellular protein modification processGO:00064641000.017
tissue remodelingGO:004877140.017
Mouse
exocytosisGO:000688710.016
protein heterooligomerizationGO:005129110.016
regulation of nucleic acid templated transcriptionGO:19035062130.016
negative regulation of reproductive processGO:200024230.016
pectoral fin developmentGO:0033339500.016
notochord developmentGO:0030903540.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
regulation of cell cycleGO:0051726520.016
regulation of cell maturationGO:190342910.016
retina development in camera type eyeGO:00600411460.016
nitric oxide metabolic processGO:004620920.016
specification of organ identityGO:001009220.016
myeloid cell differentiationGO:0030099860.016
catabolic processGO:0009056320.016
retina morphogenesis in camera type eyeGO:0060042790.016
dorsal ventral pattern formationGO:00099531250.016
hindbrain developmentGO:0030902910.016
neurological system processGO:0050877620.016
locomotory behaviorGO:0007626340.016
regulation of autophagyGO:001050630.016
cellular response to extracellular stimulusGO:003166820.016
reactive nitrogen species metabolic processGO:200105700.016
ectoderm developmentGO:000739890.016
lipid storageGO:001991510.016
Worm
regulation of gtp catabolic processGO:003312420.016
regulation of cell morphogenesis involved in differentiationGO:0010769380.015
reactive oxygen species biosynthetic processGO:190340910.015
regulation of macromolecule biosynthetic processGO:00105562250.015
regulation of calcium ion transportGO:005192420.015
bmp signaling pathwayGO:0030509520.015
synaptic vesicle endocytosisGO:004848810.015
cellular response to nutrient levelsGO:003166920.015
cell recognitionGO:0008037190.015
transcription dna templatedGO:00063511810.015
epithelial tube morphogenesisGO:00605621480.015
melanin metabolic processGO:000658220.015
regulation of mitotic cell cycleGO:0007346250.015
nitric oxide biosynthetic processGO:000680920.015
regulation of multicellular organism growthGO:004001440.015
embryonic skeletal joint developmentGO:007249830.015
regulation of cellular amine metabolic processGO:003323800.015
g2 m transition of mitotic cell cycleGO:000008640.015
membrane invaginationGO:001032410.015
behaviorGO:0007610740.015
Worm Fly
regulation of locomotionGO:0040012550.015
rna biosynthetic processGO:00327741810.015
cellular response to starvationGO:000926710.015
positive regulation of protein complex assemblyGO:003133420.015
regulation of cell developmentGO:00602841000.015
regulation of cell shapeGO:000836010.015
regulation of nervous system developmentGO:0051960900.014
regulation of establishment of protein localizationGO:007020140.014
multicellular organism growthGO:003526440.014
mesenchyme developmentGO:00604851270.014
regulation of anatomical structure sizeGO:0090066330.014
embryonic limb morphogenesisGO:003032620.014
anterior posterior pattern specificationGO:00099521520.014
neural crest cell differentiationGO:0014033720.014
regulation of transcription dna templatedGO:00063552130.014
single organism cellular localizationGO:1902580460.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.014
Worm
protein metabolic processGO:00195381830.014
synaptic transmission cholinergicGO:000727140.014
negative regulation of gene expressionGO:0010629650.014
cell cycleGO:0007049930.014
regulation of protein transportGO:005122330.014
sensory organ developmentGO:00074233930.014
neural tube patterningGO:0021532330.014
macromolecular complex subunit organizationGO:0043933740.014
guanosine containing compound catabolic processGO:190106920.013
skeletal system morphogenesisGO:00487051020.013
cellular protein metabolic processGO:00442671290.013
embryonic heart tube morphogenesisGO:00031431080.013
collateral sproutingGO:004866890.013
regulation of anterior head developmentGO:200074220.013
regulation of cell deathGO:00109411030.013
negative regulation of mesodermal cell fate specificationGO:004266230.013
regulation of cytoplasmic transportGO:190364940.013
cellular response to fibroblast growth factor stimulusGO:0044344220.013
regulation of biosynthetic processGO:00098892500.013
mitotic cell cycleGO:0000278640.013
regulation of transporter activityGO:003240920.013
gland developmentGO:00487321430.013
Mouse
morphogenesis of embryonic epitheliumGO:0016331300.013
intracellular signal transductionGO:0035556850.013
neuron differentiationGO:00301823530.013
Zebrafish
phosphorylationGO:0016310690.013
thrombocyte differentiationGO:000257440.013
striated muscle cell developmentGO:00550021080.013
fin developmentGO:0033333770.013
positive regulation of biological processGO:00485182530.013
Mouse Worm
growth plate cartilage morphogenesisGO:000342210.013
positive regulation of cellular component biogenesisGO:004408930.013
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.013
regulation of cellular protein catabolic processGO:190336210.013
embryonic neurocranium morphogenesisGO:0048702150.012
cell fate specificationGO:0001708680.012
meiotic cell cycle processGO:190304630.012
regulation of tube sizeGO:003515020.012
negative regulation of cellular metabolic processGO:0031324770.012
heart morphogenesisGO:00030071560.012
bone remodelingGO:004684920.012
Mouse
somitogenesisGO:0001756870.012
regulation of macromolecule metabolic processGO:00602553170.012
regulation of cellular amino acid metabolic processGO:000652100.012
positive regulation of map kinase activityGO:004340630.012
negative regulation of catabolic processGO:000989530.012
cell cycle g2 m phase transitionGO:004483940.012
nucleobase containing compound biosynthetic processGO:00346542050.012
cellular amino acid metabolic processGO:000652070.012
Worm
regulation of collateral sprouting in absence of injuryGO:004869640.012
negative regulation of kinase activityGO:003367340.012
negative regulation of macromolecule biosynthetic processGO:0010558480.012
embryonic digestive tract developmentGO:004856640.012
embryonic camera type eye morphogenesisGO:0048596190.012
spinal cord anterior posterior patterningGO:002151210.012
negative regulation of rna metabolic processGO:0051253480.012
single organism biosynthetic processGO:0044711710.012
Worm
organelle organizationGO:00069962270.012
embryonic pattern specificationGO:0009880440.012
release of sequestered calcium ion into cytosolGO:005120930.012
regulation of gtpase activityGO:004308720.012
negative regulation of cellular biosynthetic processGO:0031327550.012
regulation of membrane potentialGO:0042391230.012
carbohydrate biosynthetic processGO:001605110.012
striated muscle tissue developmentGO:00147061100.012
muscle tissue developmentGO:00605371100.012
regulation of cell activationGO:005086510.012
wound healingGO:0042060900.012
activation of mapk activityGO:000018730.011
non canonical wnt signaling pathwayGO:0035567130.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
regulation of neurogenesisGO:0050767870.011
anterior head developmentGO:009706520.011
positive regulation of cell adhesionGO:004578510.011
nucleic acid templated transcriptionGO:00976591810.011
autophagyGO:000691440.011
negative regulation of wnt signaling pathwayGO:0030178300.011
regulation of stem cell proliferationGO:007209120.011
protein homooligomerizationGO:005126030.011
response to alkaloidGO:004327920.011
liver developmentGO:0001889960.011
regulation of neurological system processGO:003164420.011
growth plate cartilage developmentGO:000341720.011
stem cell differentiationGO:00488631170.011
female gonad developmentGO:000858540.011
fin morphogenesisGO:0033334530.011
determination of left right asymmetry in nervous systemGO:003554540.011
regulation of developmental growthGO:0048638380.011
oxoacid metabolic processGO:0043436310.011
Worm
negative regulation of programmed cell deathGO:0043069580.011
b cell activationGO:004211320.011
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.011
single organism nuclear importGO:190259330.011
endocrine system developmentGO:0035270650.011
determination of dorsal identityGO:0048263130.011
endoderm developmentGO:0007492490.010
endosomal transportGO:001619720.010
regulation of extrinsic apoptotic signaling pathwayGO:200123630.010
regulation of blood vessel sizeGO:005088020.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.010
Worm
regulation of erk1 and erk2 cascadeGO:007037240.010
single organism organelle organizationGO:19025891990.010
intracellular transportGO:0046907320.010
positive regulation of canonical wnt signaling pathwayGO:009026340.010
oogenesisGO:0048477140.010
regulation of catalytic activityGO:0050790550.010
mesoderm developmentGO:0007498880.010
positive regulation of muscle tissue developmentGO:190186310.010

tph1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
musculoskeletal system diseaseDOID:1700.018
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
organ system cancerDOID:005068600.012