Danio rerio

117 known processes

supt5h

suppressor of Ty 5 homolog (S. cerevisiae)

(Aliases: wu:fb95e05,fb37g01,wu:fb37g01,fb95e05,etID10129.15,fog,wu:fc10f02,foggy,Spt5,etID37101.15)

supt5h biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of primary metabolic processGO:00800903110.870
cellular macromolecule metabolic processGO:00442603910.830
negative regulation of cellular processGO:00485232830.769
neuron differentiationGO:00301823530.763
regulation of response to stimulusGO:00485832690.652
Human
biosynthetic processGO:00090582940.585
larval developmentGO:000216420.570
Worm
meiotic nuclear divisionGO:000712640.567
cellular component movementGO:00069283350.528
cell morphogenesis involved in differentiationGO:00009041950.519
ubiquitin dependent protein catabolic processGO:000651130.506
regulation of cellular metabolic processGO:00313233200.491
negative regulation of biological processGO:00485193040.480
macromolecule biosynthetic processGO:00090592270.440
regulation of macromolecule metabolic processGO:00602553170.408
embryonic organ developmentGO:00485683810.390
regulation of nucleic acid templated transcriptionGO:19035062130.384
cell morphogenesis involved in neuron differentiationGO:00486671630.359
gene expressionGO:00104672520.342
cellular protein catabolic processGO:004425740.336
regulation of gene expressionGO:00104682650.333
positive regulation of metabolic processGO:00098931080.333
cell part morphogenesisGO:00329902460.332
organelle organizationGO:00069962270.330
protein modification processGO:00362111000.330
neuron projection morphogenesisGO:00488121610.314
heterocycle metabolic processGO:00464832900.310
neuron projection developmentGO:00311751800.297
positive regulation of cellular processGO:00485222010.296
neuron developmentGO:00486662620.279
regulation of biosynthetic processGO:00098892500.279
regulation of cell communicationGO:00106462320.278
Human
regulation of rna biosynthetic processGO:20011412130.271
regulation of cellular macromolecule biosynthetic processGO:20001122220.271
cellular nitrogen compound biosynthetic processGO:00442712180.271
maintenance of locationGO:005123540.264
cell migrationGO:00164772370.263
regulation of cellular biosynthetic processGO:00313262450.262
cellular nitrogen compound metabolic processGO:00346412900.260
cellular biosynthetic processGO:00442492860.253
regulation of nucleobase containing compound metabolic processGO:00192192500.250
regulation of macromolecule biosynthetic processGO:00105562250.249
cell cycle processGO:0022402530.247
chromosome organizationGO:0051276310.245
nucleobase containing compound metabolic processGO:00061392740.242
rna biosynthetic processGO:00327741810.233
regulation of cell morphogenesis involved in differentiationGO:0010769380.229
cellular protein modification processGO:00064641000.228
negative regulation of metabolic processGO:0009892860.226
protein metabolic processGO:00195381830.220
proteolysis involved in cellular protein catabolic processGO:005160330.220
regulation of signal transductionGO:00099662250.217
aorta developmentGO:003590440.216
generation of neuronsGO:00486993850.215
aromatic compound biosynthetic processGO:00194382170.213
cell projection morphogenesisGO:00488582440.208
nucleic acid metabolic processGO:00903042440.204
regulation of metabolic processGO:00192223590.200
cell surface receptor signaling pathwayGO:00071663250.199
morphogenesis of an epitheliumGO:00020093330.192
cellular protein metabolic processGO:00442671290.190
locomotionGO:00400113130.190
modification dependent protein catabolic processGO:001994130.190
deathGO:00162651210.189
transcription from rna polymerase ii promoterGO:0006366800.186
cellular component morphogenesisGO:00329893360.186
localization of cellGO:00516742440.184
brain developmentGO:00074202930.182
regulation of transcription from rna polymerase ii promoterGO:00063571140.181
regulation of rna metabolic processGO:00512522240.180
positive regulation of biological processGO:00485182530.179
positive regulation of rna metabolic processGO:0051254590.175
hematopoietic or lymphoid organ developmentGO:00485341910.173
single organism organelle organizationGO:19025891990.171
axonogenesisGO:00074091520.170
epithelial cell differentiationGO:00308551160.170
modification dependent macromolecule catabolic processGO:004363230.168
cell motilityGO:00488702440.167
cell cycleGO:0007049930.164
macromolecule modificationGO:00434121110.164
columnar cuboidal epithelial cell differentiationGO:0002065380.159
cellular aromatic compound metabolic processGO:00067252950.158
embryo development ending in birth or egg hatchingGO:00097922710.156
Worm
regulation of apoptotic processGO:0042981980.151
phosphorus metabolic processGO:00067931090.150
anterior posterior pattern specificationGO:00099521520.148
regulation of signalingGO:00230512350.147
somitogenesisGO:0001756870.147
pigmentationGO:0043473850.147
head developmentGO:00603223030.143
axon developmentGO:00615641660.136
signal transductionGO:00071654550.132
central nervous system developmentGO:00074173870.130
organic cyclic compound metabolic processGO:19013603010.130
response to external stimulusGO:00096052640.130
Human
establishment of localizationGO:00512342440.122
regulation of meiotic cell cycleGO:005144510.119
cellular macromolecule biosynthetic processGO:00346452240.118
regionalizationGO:00030022740.118
nucleic acid templated transcriptionGO:00976591810.117
proteasomal protein catabolic processGO:001049820.117
pigment cell differentiationGO:0050931380.116
regulation of nitrogen compound metabolic processGO:00511712510.116
stem cell proliferationGO:007208940.116
regulation of multicellular organismal developmentGO:20000262230.116
homeostatic processGO:00425921420.115
positive regulation of macromolecule metabolic processGO:0010604930.113
positive regulation of transcription dna templatedGO:0045893570.112
nucleobase containing compound biosynthetic processGO:00346542050.110
nucleocytoplasmic transportGO:000691340.109
cell morphogenesisGO:00009022890.109
embryonic organ morphogenesisGO:00485622740.108
stem cell differentiationGO:00488631170.108
organelle fissionGO:0048285230.107
regulation of programmed cell deathGO:00430671010.105
cellular response to chemical stimulusGO:00708871570.105
cell projection organizationGO:00300302840.105
inner ear developmentGO:00488391260.105
response to chemicalGO:00422213200.104
organic substance biosynthetic processGO:19015762890.099
protein import into nucleusGO:000660630.098
neural tube patterningGO:0021532330.094
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.094
negative regulation of nuclear divisionGO:005178430.087
g2 dna damage checkpointGO:003157230.087
positive regulation of macromolecule biosynthetic processGO:0010557590.086
mitotic cell cycleGO:0000278640.086
neural tube developmentGO:0021915620.084
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.082
chordate embryonic developmentGO:00430092710.082
mesenchymal cell differentiationGO:0048762870.079
immune system developmentGO:00025201910.079
regulation of axonogenesisGO:0050770320.079
regulation of transcription dna templatedGO:00063552130.078
positive regulation of nitrogen compound metabolic processGO:0051173690.077
nuclear transportGO:005116940.076
cytoskeleton organizationGO:0007010960.075
regulation of biological qualityGO:00650082630.075
regulation of cell differentiationGO:00455951420.075
germ cell developmentGO:0007281220.073
neural crest cell differentiationGO:0014033720.073
negative regulation of macromolecule metabolic processGO:0010605760.073
neural crest cell developmentGO:0014032620.072
establishment of protein localization to organelleGO:007259440.071
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.071
single organism metabolic processGO:00447102170.071
Human
mesenchymal cell developmentGO:0014031780.070
melanocyte differentiationGO:0030318260.068
agingGO:000756820.067
programmed cell deathGO:00125011190.067
regulation of multicellular organism growthGO:004001440.063
notch signaling pathwayGO:0007219350.061
cell proliferationGO:0008283800.060
regulation of cell projection organizationGO:0031344440.060
sexual reproductionGO:0019953360.060
positive regulation of cellular metabolic processGO:0031325940.060
rna metabolic processGO:00160702190.059
nuclear divisionGO:0000280230.059
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.058
macromolecular complex subunit organizationGO:0043933740.058
organic cyclic compound biosynthetic processGO:19013622230.058
lipid storageGO:001991510.057
regulation of anatomical structure morphogenesisGO:00226031300.057
transcription dna templatedGO:00063511810.057
regulation of neuron projection developmentGO:0010975400.056
regulation of cell deathGO:00109411030.056
apoptotic processGO:00069151160.056
regulation of multicellular organismal processGO:00512392770.056
response to stressGO:00069502630.056
Human
phosphate containing compound metabolic processGO:00067961080.055
regulation of cellular protein catabolic processGO:190336210.054
system processGO:00030081850.054
rostrocaudal neural tube patterningGO:0021903290.053
periodic partitioningGO:000736510.053
cellular process involved in reproduction in multicellular organismGO:0022412280.052
positive regulation of notch signaling pathwayGO:004574730.052
eye developmentGO:00016542770.051
endothelial cell fate commitmentGO:006083930.051
regulation of neurogenesisGO:0050767870.050
single organism reproductive processGO:0044702400.050
Worm
regulation of catalytic activityGO:0050790550.050
mitotic nuclear divisionGO:0007067180.049
sensory organ developmentGO:00074233930.049
developmental growth involved in morphogenesisGO:0060560860.049
developmental pigmentationGO:0048066480.048
cellular response to organic substanceGO:00713101050.048
reproductive processGO:0022414400.048
Worm
mesenchyme developmentGO:00604851270.046
single organism localizationGO:19025782250.045
negative regulation of ras protein signal transductionGO:004658010.045
forebrain developmentGO:0030900960.045
transportGO:00068102200.045
mitotic g2 dna damage checkpointGO:000709530.044
enzyme linked receptor protein signaling pathwayGO:00071671060.044
developmental programmed cell deathGO:001062340.044
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.044
response to organic substanceGO:00100331530.043
neuroblast proliferationGO:000740520.043
negative regulation of cellular metabolic processGO:0031324770.043
regulation of cellular component organizationGO:0051128860.043
negative regulation of gene expressionGO:0010629650.043
rna transportGO:005065820.042
regulation of developmental processGO:00507932470.042
tissue remodelingGO:004877140.042
regulation of protein metabolic processGO:0051246560.042
vesicle mediated transportGO:0016192220.041
axon guidanceGO:0007411860.041
meiotic cell cycle processGO:190304630.041
neuroepithelial cell differentiationGO:0060563260.041
stem cell developmentGO:0048864820.040
regulation of cell proliferationGO:0042127370.040
behaviorGO:0007610740.040
regulation of nervous system developmentGO:0051960900.039
chromatin modificationGO:0016568210.039
mitotic cell cycle processGO:1903047480.039
negative regulation of chromosome organizationGO:200125110.039
positive regulation of signalingGO:0023056560.039
microtubule based processGO:0007017600.038
response to uvGO:000941130.037
cellular localizationGO:0051641970.037
regulation of dna templated transcription elongationGO:003278430.037
neuron projection guidanceGO:0097485860.037
positive regulation of cellular biosynthetic processGO:0031328680.037
embryonic heart tube morphogenesisGO:00031431080.036
positive regulation of transportGO:005105020.036
nitrogen compound metabolic processGO:00068073190.036
tube morphogenesisGO:00352393490.036
mitotic dna integrity checkpointGO:004477440.036
protein complex subunit organizationGO:0071822460.035
stem cell divisionGO:001714510.035
regulation of cell cycleGO:0051726520.035
intracellular signal transductionGO:0035556850.034
phagocytosisGO:000690930.034
forebrain anterior posterior pattern specificationGO:002179730.034
semicircular canal developmentGO:0060872240.033
positive regulation of signal transductionGO:0009967560.033
negative regulation of cellular catabolic processGO:003133030.032
hemopoiesisGO:00300971830.032
heart loopingGO:0001947940.032
blood vessel morphogenesisGO:00485142160.031
developmental maturationGO:0021700340.031
response to radiationGO:0009314510.031
negative regulation of proteolysisGO:0045861100.031
inner ear morphogenesisGO:0042472630.031
regulation of protein catabolic processGO:004217610.031
gliogenesisGO:0042063450.031
protein localization to nucleusGO:003450430.031
phosphorylationGO:0016310690.030
negative regulation of rna metabolic processGO:0051253480.030
stem cell maintenanceGO:001982740.030
response to lipidGO:0033993600.030
carboxylic acid metabolic processGO:0019752220.030
somite developmentGO:0061053960.029
regulation of neuron differentiationGO:0045664560.028
cardiac muscle tissue developmentGO:0048738480.028
negative regulation of programmed cell deathGO:0043069580.028
negative regulation of biosynthetic processGO:0009890550.028
multicellular organism growthGO:003526440.028
positive regulation of apoptotic signaling pathwayGO:200123510.028
meiosis iGO:000712710.028
negative regulation of transcription dna templatedGO:0045892450.028
regulation of organelle organizationGO:0033043290.028
striated muscle tissue developmentGO:00147061100.028
response to woundingGO:00096111160.027
nuclear importGO:005117030.027
cell migration involved in heart developmentGO:0060973220.027
positive regulation of gene expressionGO:0010628710.027
transcription elongation from rna polymerase ii promoterGO:000636830.027
heart valve formationGO:000318840.027
chromosome segregationGO:0007059120.027
sensory organ morphogenesisGO:00905962000.027
cell divisionGO:0051301200.027
protein targeting to nucleusGO:004474430.026
regulation of circadian rhythmGO:004275240.026
blood circulationGO:0008015870.026
extrinsic apoptotic signaling pathwayGO:009719130.026
blood vessel developmentGO:00015682460.025
regulation of cell developmentGO:00602841000.025
odontogenesis of dentin containing toothGO:004247510.025
negative regulation of dna templated transcription elongationGO:003278510.025
forebrain neuron fate commitmentGO:002187710.024
regulation of protein transportGO:005122330.024
neurological system processGO:0050877620.024
negative regulation of rna biosynthetic processGO:1902679450.024
regulation of eye photoreceptor cell developmentGO:004247820.024
homeostasis of number of cellsGO:0048872620.024
regulation of dendrite developmentGO:005077330.024
positive regulation of response to stimulusGO:0048584800.024
Human
apoptotic process involved in developmentGO:190274220.024
taxisGO:00423301090.024
compound eye developmentGO:004874920.024
translational initiationGO:000641330.023
heart developmentGO:00075073130.023
meiotic chromosome segregationGO:004513230.023
reproductionGO:0000003400.023
Worm
brain morphogenesisGO:0048854180.023
negative regulation of nitrogen compound metabolic processGO:0051172590.023
regulation of oxidative stress induced cell deathGO:190320120.023
single organism nuclear importGO:190259330.023
negative regulation of catabolic processGO:000989530.023
cell deathGO:00082191210.023
negative regulation of neuron projection regenerationGO:007057140.023
positive regulation of biosynthetic processGO:0009891680.023
embryonic hemopoiesisGO:0035162530.023
b cell activationGO:004211320.022
outflow tract morphogenesisGO:000315110.022
regulation of protein ubiquitinationGO:003139630.022
gastrulationGO:00073692080.022
circulatory system processGO:0003013870.022
regulation of cell activationGO:005086510.022
regulation of synapse organizationGO:005080730.022
synaptic growth at neuromuscular junctionGO:005112420.021
meiotic cell cycleGO:005132150.021
negative regulation of cell communicationGO:0010648960.021
oxoacid metabolic processGO:0043436310.021
regulation of cellular component sizeGO:0032535300.021
positive regulation of neuron deathGO:190121610.021
adult behaviorGO:003053420.021
regulation of cellular protein metabolic processGO:0032268520.021
skeletal system morphogenesisGO:00487051020.021
muscle cell differentiationGO:00426921390.021
negative regulation of signalingGO:0023057960.021
vasculature developmentGO:00019442780.020
determination of heart left right asymmetryGO:00613711170.020
gland developmentGO:00487321430.020
positive regulation of catabolic processGO:000989640.020
Human
aorta morphogenesisGO:003590930.020
respiratory system developmentGO:006054150.020
cell cycle g1 s phase transitionGO:004484310.020
positive regulation of apoptotic processGO:0043065290.020
multi organism processGO:00517041340.020
regulation of bindingGO:005109830.019
regulation of developmental growthGO:0048638380.019
regulation of protein complex assemblyGO:004325430.019
response to biotic stimulusGO:0009607970.019
retina development in camera type eyeGO:00600411460.019
macromolecule localizationGO:0033036540.019
dorsal ventral pattern formationGO:00099531250.019
regulation of establishment of protein localizationGO:007020140.019
regulation of intracellular signal transductionGO:1902531570.019
cell cycle phase transitionGO:004477090.018
cognitionGO:005089010.018
primary neural tube formationGO:001402010.018
posttranscriptional gene silencing by rnaGO:003519430.018
developmental growthGO:00485891660.018
central nervous system myelinationGO:002201020.018
appendage developmentGO:0048736800.018
apoptotic process involved in morphogenesisGO:006056120.018
ear developmentGO:00435831270.018
negative regulation of nucleic acid templated transcriptionGO:1903507450.017
multicellular organism reproductionGO:0032504350.017
eye morphogenesisGO:00485921440.017
gene silencing by rnaGO:003104740.017
immune effector processGO:0002252230.017
regulation of molecular functionGO:0065009700.017
dorsal aorta morphogenesisGO:003591230.017
meiotic spindle organizationGO:000021210.017
regulation of erk1 and erk2 cascadeGO:007037240.017
negative regulation of mitosisGO:004583930.017
negative regulation of response to stimulusGO:00485851040.017
positive regulation of nucleic acid templated transcriptionGO:1903508570.017
gamete generationGO:0007276330.017
organelle assemblyGO:00709251100.017
embryonic pattern specificationGO:0009880440.017
dendrite morphogenesisGO:004881350.016
proteolysisGO:0006508380.016
urogenital system developmentGO:0001655970.016
mitotic g2 m transition checkpointGO:004481830.016
protein stabilizationGO:005082120.016
oocyte developmentGO:0048599140.016
ear morphogenesisGO:0042471640.016
neuromuscular synaptic transmissionGO:000727420.016
negative regulation of histone modificationGO:003105710.016
positive regulation of nucleobase containing compound metabolic processGO:0045935690.016
forebrain regionalizationGO:002187140.016
cell proliferation involved in heart morphogenesisGO:006132320.016
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.016
growthGO:00400071740.016
digestive tract developmentGO:00485652650.016
positive regulation of small gtpase mediated signal transductionGO:005105710.016
segment polarity determinationGO:000736710.016
regulation of organ growthGO:004662030.016
protein importGO:001703830.016
muscle organ developmentGO:00075171010.016
dorsal aorta developmentGO:003590740.015
exocytosisGO:000688710.015
regulation of protein modification by small protein conjugation or removalGO:190332030.015
small molecule metabolic processGO:0044281770.015
chromatin organizationGO:0006325220.015
regenerationGO:0031099910.015
spermatid differentiationGO:004851520.015
regulation of protein targetingGO:190353320.015
tube closureGO:006060610.015
digestive tract morphogenesisGO:00485462310.015
signal transduction in absence of ligandGO:003803410.015
regulation of cytoplasmic transportGO:190364940.015
protein phosphorylationGO:0006468470.015
nuclear exportGO:005116810.015
oligodendrocyte differentiationGO:0048709230.015
positive regulation of neuron apoptotic processGO:004352510.015
ras protein signal transductionGO:000726570.015
dna templated transcription elongationGO:000635430.015
spinal cord developmentGO:0021510460.015
negative regulation of neuron projection developmentGO:001097790.015
chemotaxisGO:00069351040.014
microtubule cytoskeleton organizationGO:0000226330.014
response to oxygen containing compoundGO:1901700550.014
epithelial tube morphogenesisGO:00605621480.014
mitotic sister chromatid segregationGO:000007060.014
atrioventricular valve formationGO:000319030.014
wound healingGO:0042060900.014
cell fate commitmentGO:0045165990.014
auditory receptor cell fate commitmentGO:000991240.014
regulation of cellular amino acid metabolic processGO:000652100.014
camera type eye developmentGO:00430102220.014
phagocytosis engulfmentGO:000691110.014
epidermal cell fate specificationGO:000995740.014
heterocycle biosynthetic processGO:00181302150.014
midbrain hindbrain boundary developmentGO:0030917230.014
keratinocyte differentiationGO:003021600.014
regulation of cell cycle processGO:0010564200.014
wnt signaling pathwayGO:0016055800.014
multicellular organismal reproductive processGO:0048609350.014
regulation of cell shapeGO:000836010.014
viral processGO:001603210.014
positive regulation of stem cell proliferationGO:200064810.014
negative regulation of nucleobase containing compound metabolic processGO:0045934590.014
embryonic skeletal system developmentGO:0048706970.014
regulation of establishment of planar polarityGO:009017540.014
hypochord developmentGO:005501630.014
cardiac atrium developmentGO:000323040.014
muscle tissue developmentGO:00605371100.014
embryonic viscerocranium morphogenesisGO:0048703520.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
nucleic acid transportGO:005065720.013
negative regulation of cell cycle phase transitionGO:190198850.013
myeloid cell differentiationGO:0030099860.013
ventricular cardiac muscle tissue morphogenesisGO:005501020.013
fin developmentGO:0033333770.013
regulation of response to external stimulusGO:0032101310.013
Human
neuron migrationGO:0001764220.013
mrna transportGO:005102820.013
histone deacetylationGO:001657520.013
negative regulation of cellular component organizationGO:0051129160.013
morphogenesis of an epithelial foldGO:006057110.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
cellular component biogenesisGO:00440851780.013
regulation of nucleocytoplasmic transportGO:004682220.013
negative regulation of histone methylationGO:003106110.013
positive regulation of cell activationGO:005086710.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.013
peripheral nervous system developmentGO:0007422550.013
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.013
regulation of cellular response to oxidative stressGO:190040720.013
regulation of cell divisionGO:0051302120.013
regulation of growthGO:0040008420.013
locomotory behaviorGO:0007626340.013
g1 s transition of mitotic cell cycleGO:000008210.012
mitotic dna damage checkpointGO:004477340.012
germ line stem cell maintenanceGO:003071820.012
mrna export from nucleusGO:000640610.012
negative regulation of apoptotic processGO:0043066550.012
regulation of cellular ketone metabolic processGO:001056570.012
erythrocyte homeostasisGO:0034101550.012
endocytosisGO:0006897160.012
locomotor rhythmGO:004547530.012
retina morphogenesis in camera type eyeGO:0060042790.012
lipid metabolic processGO:0006629520.012
positive regulation of cellular amine metabolic processGO:003324000.012
small gtpase mediated signal transductionGO:000726480.012
endodermal cell differentiationGO:0035987190.012
response to light stimulusGO:0009416460.012
regulation of phosphorus metabolic processGO:0051174430.012
iron ion transportGO:000682640.012
mitotic cell cycle phase transitionGO:004477290.012
regulation of neural precursor cell proliferationGO:200017730.012
myeloid cell homeostasisGO:0002262560.012
lateral inhibitionGO:004633110.012
immune system processGO:00023762410.012
positive regulation of map kinase activityGO:004340630.012
polyol metabolic processGO:001975110.012
regulation of cell motilityGO:2000145460.012
pharyngeal muscle developmentGO:004328240.012
mitotic spindle organizationGO:000705250.011
sensory neuron axon guidanceGO:009737430.011
hepaticobiliary system developmentGO:0061008980.011
cartilage developmentGO:0051216960.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
regulation of oligodendrocyte differentiationGO:004871310.011
central nervous system neuron differentiationGO:0021953740.011

supt5h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.105
endocrine gland cancerDOID:17000.105
cancerDOID:16200.105
organ system cancerDOID:005068600.105
disease of anatomical entityDOID:700.021
reproductive organ cancerDOID:19300.017
nervous system diseaseDOID:86300.012