Danio rerio

19 known processes

tpp1

tripeptidyl peptidase I

(Aliases: wu:fa01b09,fa01b09,im:7149243,cln2)

tpp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory organ developmentGO:00074233930.525
eye developmentGO:00016542770.487
sensory organ morphogenesisGO:00905962000.380
neurological system processGO:0050877620.371
Mouse
response to chemicalGO:00422213200.325
regulation of multicellular organismal developmentGO:20000262230.242
localization of cellGO:00516742440.200
transportGO:00068102200.193
camera type eye developmentGO:00430102220.181
larval developmentGO:000216420.178
retina development in camera type eyeGO:00600411460.170
membrane repolarizationGO:008600920.164
regulation of multicellular organismal processGO:00512392770.159
retina layer formationGO:0010842240.139
cell motilityGO:00488702440.134
establishment of localizationGO:00512342440.130
embryo development ending in birth or egg hatchingGO:00097922710.127
response to drugGO:004249330.125
proteolysis involved in cellular protein catabolic processGO:005160330.125
generation of neuronsGO:00486993850.118
locomotionGO:00400113130.104
fin morphogenesisGO:0033334530.101
organelle organizationGO:00069962270.099
Mouse
cellular component movementGO:00069283350.099
regulation of biological qualityGO:00650082630.094
neural retina developmentGO:0003407490.092
establishment of epithelial cell polarityGO:009016220.091
cellular component assemblyGO:00226071700.091
regulation of anatomical structure morphogenesisGO:00226031300.090
embryonic organ developmentGO:00485683810.089
regulation of developmental processGO:00507932470.084
neural crest cell migrationGO:0001755420.078
single organism organelle organizationGO:19025891990.077
cell morphogenesis involved in differentiationGO:00009041950.074
pigmentationGO:0043473850.070
phagocytosisGO:000690930.069
cell migrationGO:00164772370.069
pectoral fin developmentGO:0033339500.068
cellular component morphogenesisGO:00329893360.068
lipid storageGO:001991510.064
heterocycle metabolic processGO:00464832900.064
single organism metabolic processGO:00447102170.064
developmental cell growthGO:0048588520.064
deathGO:00162651210.063
growthGO:00400071740.061
embryonic organ morphogenesisGO:00485622740.061
multicellular organism growthGO:003526440.059
cell cycle g1 s phase transitionGO:004484310.058
brain developmentGO:00074202930.058
cellular nitrogen compound metabolic processGO:00346412900.058
cell projection organizationGO:00300302840.058
eye morphogenesisGO:00485921440.057
golgi vesicle transportGO:004819330.056
nucleocytoplasmic transportGO:000691340.056
fin developmentGO:0033333770.054
modification dependent macromolecule catabolic processGO:004363230.054
cytoskeleton organizationGO:0007010960.053
ameboidal type cell migrationGO:00016671430.052
nuclear transportGO:005116940.052
positive regulation of transportGO:005105020.051
regulation of signalingGO:00230512350.049
regulation of protein modification by small protein conjugation or removalGO:190332030.049
axonogenesisGO:00074091520.048
negative regulation of biological processGO:00485193040.047
sensory system developmentGO:0048880760.047
cellular response to chemical stimulusGO:00708871570.046
negative regulation of cellular processGO:00485232830.045
outflow tract morphogenesisGO:000315110.045
nucleobase containing compound metabolic processGO:00061392740.045
action potentialGO:0001508190.045
organic cyclic compound metabolic processGO:19013603010.045
establishment of protein localization to organelleGO:007259440.045
retinal ganglion cell axon guidanceGO:0031290350.045
cellular component biogenesisGO:00440851780.045
axon developmentGO:00615641660.044
cell deathGO:00082191210.044
neuromast developmentGO:0048884460.044
heart developmentGO:00075073130.044
neuron differentiationGO:00301823530.044
cell morphogenesis involved in neuron differentiationGO:00486671630.044
cellular macromolecule metabolic processGO:00442603910.043
positive regulation of metabolic processGO:00098931080.043
neuron projection developmentGO:00311751800.042
ubiquitin dependent protein catabolic processGO:000651130.042
cellular protein catabolic processGO:004425740.041
head developmentGO:00603223030.041
cell part morphogenesisGO:00329902460.041
regulation of neuron differentiationGO:0045664560.041
agingGO:000756820.041
lateral line system developmentGO:0048925760.041
rna metabolic processGO:00160702190.039
regulation of neurotransmitter transportGO:005158810.038
axon guidanceGO:0007411860.038
nucleic acid metabolic processGO:00903042440.038
central nervous system developmentGO:00074173870.038
cation transportGO:0006812810.038
positive regulation of cellular processGO:00485222010.037
ear developmentGO:00435831270.037
phosphate containing compound metabolic processGO:00067961080.037
cell morphogenesisGO:00009022890.037
polarized epithelial cell differentiationGO:003085940.037
regulation of neurogenesisGO:0050767870.037
positive regulation of glucose transportGO:001082810.036
cellular response to organic substanceGO:00713101050.036
neuron developmentGO:00486662620.036
sympathetic nervous system developmentGO:004848530.035
regulation of metabolic processGO:00192223590.035
single organism localizationGO:19025782250.035
neuron projection morphogenesisGO:00488121610.035
regulation of cellular component organizationGO:0051128860.034
cellular response to topologically incorrect proteinGO:003596720.034
response to stressGO:00069502630.034
stem cell proliferationGO:007208940.034
nucleoside monophosphate catabolic processGO:000912540.034
gland developmentGO:00487321430.033
adult behaviorGO:003053420.033
nitrogen compound metabolic processGO:00068073190.032
negative regulation of axon guidanceGO:190266810.031
appendage morphogenesisGO:0035107560.030
camera type eye morphogenesisGO:00485931080.030
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.030
glial cell migrationGO:000834730.030
mitotic cell cycle processGO:1903047480.030
purine containing compound metabolic processGO:0072521290.030
stem cell fate commitmentGO:004886510.029
morphogenesis of an epitheliumGO:00020093330.029
regulation of multicellular organism growthGO:004001440.028
protein metabolic processGO:00195381830.028
appendage developmentGO:0048736800.028
cell projection morphogenesisGO:00488582440.028
regulation of cell shapeGO:000836010.028
pectoral fin morphogenesisGO:0035138290.028
regulation of organ growthGO:004662030.028
skeletal system developmentGO:00015011810.028
autophagyGO:000691440.028
symbiosis encompassing mutualism through parasitismGO:004440340.028
circulatory system processGO:0003013870.027
regulation of intracellular protein transportGO:003315730.027
regulation of cell communicationGO:00106462320.027
viral processGO:001603210.027
digestive system developmentGO:00551232890.026
spindle assemblyGO:005122520.026
negative regulation of cytokine mediated signaling pathwayGO:000196020.026
negative regulation of programmed cell deathGO:0043069580.026
nerve developmentGO:0021675450.026
epithelial cell differentiationGO:00308551160.026
microtubule based processGO:0007017600.026
modification dependent protein catabolic processGO:001994130.026
atp catabolic processGO:000620040.026
response to vitaminGO:003327330.026
cellular response to external stimulusGO:007149620.026
chemotaxisGO:00069351040.025
cortical cytoskeleton organizationGO:003086510.025
regulation of cellular protein catabolic processGO:190336210.025
positive regulation of secretionGO:005104710.025
protein polyubiquitinationGO:000020940.025
regulation of nervous system developmentGO:0051960900.024
regulation of axonogenesisGO:0050770320.024
hemopoiesisGO:00300971830.024
developmental growthGO:00485891660.024
establishment of epithelial cell apical basal polarityGO:004519820.024
sensory perceptionGO:0007600390.024
cellular amide metabolic processGO:004360340.024
maintenance of locationGO:005123540.024
interaction with hostGO:005170140.024
regulation of i kappab kinase nf kappab signalingGO:004312240.024
developmental pigmentationGO:0048066480.024
purine ribonucleoside monophosphate catabolic processGO:000916940.024
g1 s transition of mitotic cell cycleGO:000008210.023
programmed cell deathGO:00125011190.023
establishment or maintenance of bipolar cell polarityGO:0061245120.023
small molecule metabolic processGO:0044281770.023
single organism transportGO:00447652060.023
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.023
cell surface receptor signaling pathwayGO:00071663250.023
regulation of programmed cell deathGO:00430671010.023
muscle structure developmentGO:00610611960.022
ribonucleoside monophosphate catabolic processGO:000915840.022
signal transductionGO:00071654550.022
homeostatic processGO:00425921420.022
cellular response to light stimulusGO:007148240.022
regulation of protein ubiquitinationGO:003139630.022
response to abiotic stimulusGO:00096281220.022
response to light stimulusGO:0009416460.022
cellular response to endogenous stimulusGO:0071495680.022
positive regulation of glucose importGO:004632610.021
establishment of apical basal cell polarityGO:003508920.021
regulation of bindingGO:005109830.021
protein complex biogenesisGO:0070271300.021
establishment or maintenance of cell polarityGO:0007163290.021
transmembrane transportGO:00550851200.021
regulation of cell deathGO:00109411030.021
negative regulation of axon extension involved in axon guidanceGO:004884310.021
cognitionGO:005089010.021
system processGO:00030081850.020
Mouse
telomere organizationGO:003220010.020
pigment cell differentiationGO:0050931380.020
positive regulation of cell cycleGO:004578730.020
nuclear exportGO:005116810.020
actin filament based processGO:0030029640.020
regulation of cellular metabolic processGO:00313233200.020
cellular aromatic compound metabolic processGO:00067252950.020
protein polymerizationGO:005125840.020
regulation of response to stimulusGO:00485832690.020
telomere maintenanceGO:000072310.020
organelle fusionGO:004828430.019
rna processingGO:0006396250.019
cortical actin cytoskeleton organizationGO:003086610.019
cellular response to oxygen containing compoundGO:1901701200.019
regulation of synapse organizationGO:005080730.019
regenerationGO:0031099910.019
response to oxygen containing compoundGO:1901700550.019
regulation of primary metabolic processGO:00800903110.019
organelle localizationGO:0051640490.019
establishment of monopolar cell polarityGO:006116220.019
positive regulation of catabolic processGO:000989640.019
response to glucocorticoidGO:005138410.019
regulation of rna metabolic processGO:00512522240.019
positive regulation of secretion by cellGO:190353210.019
apoptotic processGO:00069151160.019
organic substance transportGO:0071702580.019
single fertilizationGO:000733830.019
behaviorGO:0007610740.019
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.019
response to endogenous stimulusGO:0009719830.019
regulation of cell motilityGO:2000145460.018
regulation of mrna processingGO:005068430.018
organic substance biosynthetic processGO:19015762890.018
cranial nerve developmentGO:0021545420.018
neural crest cell developmentGO:0014032620.018
toxin transportGO:190199820.018
regulation of autophagyGO:001050630.018
proteasomal protein catabolic processGO:001049820.018
inositol phosphate metabolic processGO:004364710.018
gene expressionGO:00104672520.018
g2 dna damage checkpointGO:003157230.018
embryonic cranial skeleton morphogenesisGO:0048701900.018
response to lipidGO:0033993600.017
specification of symmetryGO:00097992040.017
interspecies interaction between organismsGO:004441940.017
regulation of tube sizeGO:003515020.017
morphogenesis of follicular epitheliumGO:001633310.017
commissural neuron axon guidanceGO:007167930.017
axon extensionGO:0048675450.017
nucleobase containing compound biosynthetic processGO:00346542050.017
axon midline choice point recognitionGO:001619940.017
regulation of nucleoside metabolic processGO:000911820.017
aromatic compound biosynthetic processGO:00194382170.017
post embryonic organ developmentGO:004856940.016
cell adhesion mediated by integrinGO:003362710.016
regulation of mitotic cell cycleGO:0007346250.016
stem cell maintenanceGO:001982740.016
actin cytoskeleton organizationGO:0030036630.016
positive regulation of translationGO:004572710.016
cellular component disassemblyGO:002241110.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
neuron projection guidanceGO:0097485860.016
regulation of signal transductionGO:00099662250.016
regulation of glucose importGO:004632410.016
i kappab kinase nf kappab signalingGO:000724940.016
vasculature developmentGO:00019442780.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
mesenchymal cell developmentGO:0014031780.016
protein importGO:001703830.016
lamellipodium assemblyGO:003003210.016
cellular amine metabolic processGO:004410620.016
retina morphogenesis in camera type eyeGO:0060042790.016
heterocycle biosynthetic processGO:00181302150.015
purine nucleoside monophosphate catabolic processGO:000912840.015
regulation of membrane potentialGO:0042391230.015
response to nutrientGO:000758430.015
inner ear developmentGO:00488391260.015
regulation of extent of cell growthGO:0061387290.015
small molecule catabolic processGO:004428230.015
protein complex subunit organizationGO:0071822460.015
response to organic substanceGO:00100331530.015
response to external stimulusGO:00096052640.015
glucose importGO:004632320.015
regulation of cell developmentGO:00602841000.015
embryonic skeletal joint developmentGO:007249830.015
tissue regenerationGO:0042246740.015
mrna transportGO:005102820.015
protein complex disassemblyGO:004324110.015
positive regulation of cell matrix adhesionGO:000195410.015
rna 3 end processingGO:003112320.015
exocytosisGO:000688710.015
cellular response to hormone stimulusGO:0032870390.015
midbrain developmentGO:0030901280.015
multi organism cellular processGO:004476420.015
pancreas developmentGO:0031016840.015
hindbrain developmentGO:0030902910.015
cartilage condensationGO:000150230.015
tube closureGO:006060610.014
neural tube developmentGO:0021915620.014
protein complex assemblyGO:0006461300.014
primary neural tube formationGO:001402010.014
melanin metabolic processGO:000658220.014
cellular carbohydrate metabolic processGO:004426240.014
gtp metabolic processGO:004603940.014
negative regulation of apoptotic processGO:0043066550.014
cellular response to extracellular stimulusGO:003166820.014
cell growthGO:0016049570.014
neural nucleus developmentGO:0048857150.014
neuroblast proliferationGO:000740520.014
establishment of localization in cellGO:0051649770.014
endosome organizationGO:000703220.014
synaptic vesicle recyclingGO:003646510.014
negative regulation of signal transductionGO:0009968940.014
central nervous system neuron differentiationGO:0021953740.014
regulation of cellular ketone metabolic processGO:001056570.014
regulation of cell sizeGO:0008361290.014
myelination of anterior lateral line nerve axonsGO:004891430.014
neuron neuron synaptic transmissionGO:000727010.014
ion transportGO:00068111140.014
organonitrogen compound metabolic processGO:1901564740.014
single organism membrane organizationGO:0044802200.013
positive regulation of cellular catabolic processGO:003133130.013
skeletal system morphogenesisGO:00487051020.013
response to radiationGO:0009314510.013
regulation of locomotionGO:0040012550.013
mitotic g2 dna damage checkpointGO:000709530.013
amine metabolic processGO:000930820.013
mrna export from nucleusGO:000640610.013
immune system processGO:00023762410.013
cellular response to starvationGO:000926710.013
renal filtrationGO:0097205100.013
single organism membrane fusionGO:004480120.013
organic acid metabolic processGO:0006082310.013
determination of bilateral symmetryGO:00098552040.013
lamellipodium organizationGO:009758110.013
negative regulation of signal transduction in absence of ligandGO:190109910.013
tube morphogenesisGO:00352393490.013
cellular biosynthetic processGO:00442492860.013
endosomal transportGO:001619720.013
response to ketoneGO:190165410.013
regulation of cell activationGO:005086510.013
female gonad developmentGO:000858540.013
anatomical structure arrangementGO:004853220.013
startle responseGO:000196440.013
regulation of apoptotic processGO:0042981980.013
cell matrix adhesionGO:000716040.012
odontogenesis of dentin containing toothGO:004247510.012
regulation of developmental growthGO:0048638380.012
cell cycle processGO:0022402530.012
epithelial tube morphogenesisGO:00605621480.012
cellular ketone metabolic processGO:0042180110.012
response to corticosteroidGO:003196010.012
regulation of cytokine productionGO:000181730.012
regulation of glucose transportGO:001082710.012
centrosome cycleGO:000709810.012
cell adhesionGO:0007155400.012
membrane organizationGO:0061024210.012
wound healingGO:0042060900.012
single organism nuclear importGO:190259330.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.012
positive regulation of chromosome organizationGO:200125210.012
inorganic ion transmembrane transportGO:0098660570.012
developmental growth involved in morphogenesisGO:0060560860.012
positive regulation of map kinase activityGO:004340630.012
mesodermal cell migrationGO:0008078120.012
embryonic skeletal joint morphogenesisGO:006027230.012
polyol metabolic processGO:001975110.012
anterior lateral line nerve glial cell developmentGO:004893930.012
microtubule cytoskeleton organization involved in mitosisGO:190285010.012
sensory neuron axon guidanceGO:009737430.012
organelle assemblyGO:00709251100.012
exocrine system developmentGO:0035272280.012
heart morphogenesisGO:00030071560.011
regulation of protein catabolic processGO:004217610.011
mrna 3 end processingGO:003112420.011
regulation of protein bindingGO:004339330.011
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.011
negative regulation of stem cell differentiationGO:200073720.011
response to alcoholGO:0097305140.011
regulation of rna biosynthetic processGO:20011412130.011
negative regulation of macromolecule metabolic processGO:0010605760.011
negative regulation of gene expressionGO:0010629650.011
multicellular organismal signalingGO:0035637220.011
regulation of growthGO:0040008420.011
regulation of protein complex assemblyGO:004325430.011
cellular response to stressGO:0033554620.011
regulation of gene expressionGO:00104682650.011
nuclear importGO:005117030.011
regulation of dendrite morphogenesisGO:004881430.011
ribonucleoprotein complex biogenesisGO:0022613130.011
meiotic chromosome segregationGO:004513230.011
neuromuscular synaptic transmissionGO:000727420.011
negative regulation of cell deathGO:0060548600.011
cardiac conductionGO:006133730.011
axon ensheathment in central nervous systemGO:003229120.011
cellular protein modification processGO:00064641000.011
central nervous system myelinationGO:002201020.011
mitotic dna damage checkpointGO:004477340.011
anterior lateral line nerve glial cell differentiationGO:004891330.010
macromolecular complex assemblyGO:0065003350.010
leukocyte proliferationGO:007066110.010
enzyme linked receptor protein signaling pathwayGO:00071671060.010
myelinationGO:0042552180.010
regulation of nitrogen compound metabolic processGO:00511712510.010
regulation of cell differentiationGO:00455951420.010
regulation of synaptic plasticityGO:004816710.010
cellular localizationGO:0051641970.010
organic substance catabolic processGO:1901575280.010
digestive tract developmentGO:00485652650.010
positive regulation of cell adhesionGO:004578510.010
macromolecular complex subunit organizationGO:0043933740.010
stem cell developmentGO:0048864820.010
photoreceptor cell differentiationGO:0046530550.010
cellular response to nutrient levelsGO:003166920.010
regulation of cellular amino acid metabolic processGO:000652100.010
purine nucleotide metabolic processGO:0006163270.010
centrosome organizationGO:005129710.010

tpp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.121
nervous system diseaseDOID:86300.047
musculoskeletal system diseaseDOID:1700.014
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011
disease of cellular proliferationDOID:1456600.010