Danio rerio

7 known processes

gcga

glucagon a and glucagon a-like

(Aliases: zgc:103616,glu,gcg)

gcga biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
enteroendocrine cell differentiationGO:003588390.364
endocrine pancreas developmentGO:0031018270.357
sensory organ developmentGO:00074233930.357
endocrine system developmentGO:0035270650.352
cell motilityGO:00488702440.351
pancreas developmentGO:0031016840.284
specification of symmetryGO:00097992040.270
determination of bilateral symmetryGO:00098552040.244
response to chemicalGO:00422213200.225
hematopoietic or lymphoid organ developmentGO:00485341910.215
cellular component movementGO:00069283350.180
type b pancreatic cell developmentGO:000332340.167
cellular response to chemical stimulusGO:00708871570.147
regionalizationGO:00030022740.147
response to stressGO:00069502630.146
larval developmentGO:000216420.139
hormone secretionGO:004687920.134
regulation of signal transductionGO:00099662250.134
response to carbohydrateGO:000974330.133
sensory organ morphogenesisGO:00905962000.126
localization of cellGO:00516742440.122
heart developmentGO:00075073130.120
gastrulationGO:00073692080.116
monovalent inorganic cation transportGO:0015672420.116
embryonic organ developmentGO:00485683810.115
regulation of bindingGO:005109830.114
digestive tract morphogenesisGO:00485462310.111
regulation of signalingGO:00230512350.109
dorsal ventral pattern formationGO:00099531250.108
cellular macromolecule metabolic processGO:00442603910.107
inner ear morphogenesisGO:0042472630.100
regulation of hormone secretionGO:004688320.100
cellular ketone metabolic processGO:0042180110.097
response to drugGO:004249330.096
epithelial cell differentiationGO:00308551160.093
vasculature developmentGO:00019442780.093
negative regulation of cell communicationGO:0010648960.092
response to external stimulusGO:00096052640.089
cell migrationGO:00164772370.089
tube morphogenesisGO:00352393490.088
type b pancreatic cell differentiationGO:000330980.086
adult behaviorGO:003053420.085
regulation of organ growthGO:004662030.085
regulation of embryonic developmentGO:0045995470.084
hindbrain developmentGO:0030902910.084
regulation of metabolic processGO:00192223590.080
embryo development ending in birth or egg hatchingGO:00097922710.078
regulation of response to stimulusGO:00485832690.077
regulation of peptidyl tyrosine phosphorylationGO:005073010.077
rna metabolic processGO:00160702190.077
enzyme linked receptor protein signaling pathwayGO:00071671060.076
regulation of cell communicationGO:00106462320.075
regulation of molecular functionGO:0065009700.074
anterior posterior pattern specificationGO:00099521520.074
hormone transportGO:000991420.074
response to ketoneGO:190165410.073
negative regulation of cellular processGO:00485232830.073
epithelial cell developmentGO:0002064420.072
peptide transportGO:001583310.071
embryonic organ morphogenesisGO:00485622740.070
regulation of transcription dna templatedGO:00063552130.069
protein localization to nucleusGO:003450430.069
ear developmentGO:00435831270.066
morphogenesis of an epitheliumGO:00020093330.064
segmentationGO:0035282970.064
immune system developmentGO:00025201910.063
determination of left right symmetryGO:00073681790.063
organic cyclic compound biosynthetic processGO:19013622230.063
glucose homeostasisGO:004259310.063
chordate embryonic developmentGO:00430092710.062
nuclear transportGO:005116940.062
central nervous system developmentGO:00074173870.061
cellular amino acid metabolic processGO:000652070.060
foregut morphogenesisGO:000744040.060
camera type eye developmentGO:00430102220.060
urogenital system developmentGO:0001655970.060
sensory system developmentGO:0048880760.060
amine metabolic processGO:000930820.058
response to nutrientGO:000758430.058
immune system processGO:00023762410.058
renal system developmentGO:0072001940.058
regulation of cellular component movementGO:0051270550.058
response to organic cyclic compoundGO:0014070510.057
nucleocytoplasmic transportGO:000691340.056
nitrogen compound metabolic processGO:00068073190.056
columnar cuboidal epithelial cell differentiationGO:0002065380.055
inner ear developmentGO:00488391260.054
cellular biosynthetic processGO:00442492860.054
negative regulation of signalingGO:0023057960.054
eye developmentGO:00016542770.054
amide transportGO:0042886120.053
positive regulation of transportGO:005105020.053
cellular response to external stimulusGO:007149620.052
biosynthetic processGO:00090582940.052
establishment of localizationGO:00512342440.052
hemopoiesisGO:00300971830.051
regulation of cellular amine metabolic processGO:003323800.051
regulation of transcription from rna polymerase ii promoterGO:00063571140.051
response to hexoseGO:000974630.051
regulation of nitrogen compound metabolic processGO:00511712510.050
positive regulation of muscle tissue developmentGO:190186310.050
regulation of neuron migrationGO:200122220.050
regulation of cellular metabolic processGO:00313233200.049
er nucleus signaling pathwayGO:000698420.049
regulation of cellular amino acid metabolic processGO:000652100.048
regulation of multicellular organismal developmentGO:20000262230.048
mesenchyme developmentGO:00604851270.047
neural tube developmentGO:0021915620.047
nucleobase containing compound metabolic processGO:00061392740.047
regulation of macromolecule metabolic processGO:00602553170.046
protein metabolic processGO:00195381830.046
cellular amine metabolic processGO:004410620.046
regulation of cell motilityGO:2000145460.046
regenerationGO:0031099910.045
neural tube patterningGO:0021532330.045
gland developmentGO:00487321430.045
signal transductionGO:00071654550.045
cell projection morphogenesisGO:00488582440.045
gene expressionGO:00104672520.044
multicellular organism growthGO:003526440.044
positive regulation of signal transductionGO:0009967560.044
cellular response to estrogen stimulusGO:0071391240.044
wound healingGO:0042060900.043
regulation of protein catabolic processGO:004217610.043
carbohydrate homeostasisGO:003350010.043
apoptotic processGO:00069151160.042
single organism nuclear importGO:190259330.042
regulation of nucleic acid templated transcriptionGO:19035062130.041
embryonic skeletal system morphogenesisGO:0048704930.041
carboxylic acid metabolic processGO:0019752220.041
protein importGO:001703830.041
spinal cord developmentGO:0021510460.040
pancreatic a cell developmentGO:000332220.040
locomotionGO:00400113130.040
positive regulation of signalingGO:0023056560.040
embryonic heart tube developmentGO:00350501330.040
positive regulation of biological processGO:00485182530.040
cellular response to organic substanceGO:00713101050.039
otic vesicle formationGO:0030916270.039
regulation of blood pressureGO:000821710.039
cell morphogenesisGO:00009022890.039
alpha amino acid metabolic processGO:190160530.038
regulation of sodium ion transportGO:000202820.038
negative regulation of blood circulationGO:190352320.037
response to monosaccharideGO:003428430.037
positive regulation of response to stimulusGO:0048584800.037
kidney developmentGO:0001822920.037
multi organism processGO:00517041340.036
negative regulation of signal transductionGO:0009968940.036
regulation of multicellular organism growthGO:004001440.036
regulation of localizationGO:00328791040.036
agingGO:000756820.036
regulation of protein targetingGO:190353320.036
eye morphogenesisGO:00485921440.036
otic vesicle developmentGO:0071599420.036
development of primary female sexual characteristicsGO:004654540.036
neuron developmentGO:00486662620.035
regulation of biosynthetic processGO:00098892500.035
neuromast developmentGO:0048884460.035
protein targeting to nucleusGO:004474430.035
cellular nitrogen compound metabolic processGO:00346412900.035
liver developmentGO:0001889960.035
regulation of protein bindingGO:004339330.035
carbon dioxide transportGO:001567030.034
epibolyGO:0090504410.034
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005930.034
digestive system developmentGO:00551232890.034
response to glucoseGO:000974930.034
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.034
cell projection organizationGO:00300302840.034
heart loopingGO:0001947940.033
canonical wnt signaling pathwayGO:0060070480.033
intracellular signal transductionGO:0035556850.033
somitogenesisGO:0001756870.033
response to woundingGO:00096111160.033
response to nicotineGO:003509420.033
synaptic target recognitionGO:000803910.033
cellular response to organic cyclic compoundGO:0071407380.032
regulation of cellular ketone metabolic processGO:001056570.032
lipid storageGO:001991510.032
generation of neuronsGO:00486993850.032
positive regulation of cellular amine metabolic processGO:003324000.032
cell part morphogenesisGO:00329902460.032
digestive tract developmentGO:00485652650.032
regulation of extrinsic apoptotic signaling pathwayGO:200123630.032
regulation of intracellular protein transportGO:003315730.031
angiogenesisGO:00015251580.031
response to hormoneGO:0009725480.031
cardiac atrium morphogenesisGO:000320920.031
lateral line developmentGO:0048882660.031
rna biosynthetic processGO:00327741810.031
lymphatic endothelial cell differentiationGO:006083610.031
nitric oxide mediated signal transductionGO:000726320.031
cell morphogenesis involved in neuron differentiationGO:00486671630.030
transcription dna templatedGO:00063511810.030
regulation of cell migrationGO:0030334400.030
positive regulation of neuron migrationGO:200122420.030
regulation of protein transportGO:005122330.029
cell differentiation in spinal cordGO:0021515400.029
nucleic acid templated transcriptionGO:00976591810.029
rostrocaudal neural tube patterningGO:0021903290.029
transportGO:00068102200.029
regulation of reproductive processGO:200024140.029
heterocycle metabolic processGO:00464832900.029
negative regulation of metabolic processGO:0009892860.029
establishment of protein localization to organelleGO:007259440.028
membrane fusionGO:006102520.028
midbrain hindbrain boundary developmentGO:0030917230.028
endocardial cushion developmentGO:000319760.028
intracellular estrogen receptor signaling pathwayGO:003052030.028
cell surface receptor signaling pathwayGO:00071663250.028
catechol containing compound biosynthetic processGO:000971320.028
transcription from rna polymerase ii promoterGO:0006366800.028
extrinsic apoptotic signaling pathwayGO:009719130.027
cell cycle arrestGO:000705010.027
cellular component biogenesisGO:00440851780.027
oxoacid metabolic processGO:0043436310.027
negative regulation of biological processGO:00485193040.027
cell migration involved in heart formationGO:0060974100.027
regulation of developmental processGO:00507932470.027
developmental programmed cell deathGO:001062340.027
single organism organelle organizationGO:19025891990.027
negative regulation of response to stimulusGO:00485851040.027
cellular macromolecule biosynthetic processGO:00346452240.026
positive regulation of epithelial cell differentiationGO:003085820.026
endocardial cushion morphogenesisGO:000320330.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.026
regulation of gene expressionGO:00104682650.026
regulation of catalytic activityGO:0050790550.025
blood vessel morphogenesisGO:00485142160.025
regulation of jak stat cascadeGO:004642530.025
regulation of locomotionGO:0040012550.025
regulation of protein localization to nucleusGO:190018020.025
neuron differentiationGO:00301823530.025
positive regulation of gene expressionGO:0010628710.025
embryonic heart tube morphogenesisGO:00031431080.025
negative regulation of macromolecule metabolic processGO:0010605760.025
regulation of protein import into nucleusGO:004230620.024
regulation of nucleobase containing compound metabolic processGO:00192192500.024
regulation of cell differentiationGO:00455951420.024
photoreceptor cell fate commitmentGO:004655210.024
cellular response to starvationGO:000926710.024
cellular aldehyde metabolic processGO:000608140.024
retinal metabolic processGO:004257430.024
stem cell developmentGO:0048864820.024
tissue regenerationGO:0042246740.024
positive regulation of nucleotide catabolic processGO:003081310.024
response to steroid hormoneGO:0048545350.024
regulation of transcription from rna polymerase iii promoterGO:000635910.024
response to amphetamineGO:000197510.023
nuclear importGO:005117030.023
dendrite guidanceGO:007098300.023
striated muscle cell differentiationGO:00511461290.023
heterocycle biosynthetic processGO:00181302150.023
mitochondrion organizationGO:000700540.023
sensory perception of chemical stimulusGO:000760630.023
neuron projection developmentGO:00311751800.023
positive regulation of muscle organ developmentGO:004863610.023
behaviorGO:0007610740.023
aromatic compound biosynthetic processGO:00194382170.023
tissue remodelingGO:004877140.023
regulation of transcription involved in cell fate commitmentGO:006085010.023
blood vessel developmentGO:00015682460.023
olfactory bulb axon guidanceGO:007167830.023
negative regulation of gene expressionGO:0010629650.022
regulation of establishment of protein localizationGO:007020140.022
regulation of metal ion transportGO:001095940.022
retina development in camera type eyeGO:00600411460.022
photoreceptor cell differentiationGO:0046530550.022
astrocyte differentiationGO:004870810.022
morphogenesis of an epithelial sheetGO:0002011490.022
positive regulation of catabolic processGO:000989640.021
appendage morphogenesisGO:0035107560.021
negative regulation of nucleic acid templated transcriptionGO:1903507450.021
negative regulation of hormone secretionGO:004688820.021
response to xenobiotic stimulusGO:0009410450.021
gastrulation with mouth forming secondGO:0001702440.021
positive regulation of canonical wnt signaling pathwayGO:009026340.021
cell cycle g2 m phase transitionGO:004483940.021
positive regulation of cell communicationGO:0010647560.021
axonogenesisGO:00074091520.021
stem cell differentiationGO:00488631170.020
heart morphogenesisGO:00030071560.020
regulation of primary metabolic processGO:00800903110.020
positive regulation of nitrogen compound metabolic processGO:0051173690.020
regulation of cellular response to growth factor stimulusGO:0090287350.020
olfactory bulb developmentGO:002177240.020
embryonic skeletal system developmentGO:0048706970.020
cellular response to nutrient levelsGO:003166920.020
embryonic skeletal joint developmentGO:007249830.020
response to glucocorticoidGO:005138410.020
phagocytosis engulfmentGO:000691110.019
phagocytosisGO:000690930.019
b cell activationGO:004211320.019
regulation of multicellular organismal processGO:00512392770.019
glandular epithelial cell differentiationGO:000206790.019
protein import into nucleusGO:000660630.019
cell cell signalingGO:0007267520.019
neuron apoptotic processGO:0051402200.019
cellular response to reactive oxygen speciesGO:003461420.019
negative regulation of gastrulationGO:2000542110.019
cell growthGO:0016049570.019
response to abiotic stimulusGO:00096281220.019
embryonic digestive tract morphogenesisGO:004855730.019
positive regulation of cellular catabolic processGO:003133130.018
organic substance transportGO:0071702580.018
regulation of protein complex assemblyGO:004325430.018
floor plate developmentGO:0033504150.018
regulation of rna metabolic processGO:00512522240.018
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.018
appendage developmentGO:0048736800.018
rhombomere 5 developmentGO:002157140.018
organic acid metabolic processGO:0006082310.018
negative regulation of kinase activityGO:003367340.018
ameboidal type cell migrationGO:00016671430.018
forebrain regionalizationGO:002187140.018
response to inorganic substanceGO:0010035380.018
skeletal system developmentGO:00015011810.018
positive regulation of cytokine productionGO:000181920.018
gtp catabolic processGO:000618420.018
cellular protein modification processGO:00064641000.018
regulation of anatomical structure morphogenesisGO:00226031300.017
oocyte maturationGO:000155640.017
heart contractionGO:0060047710.017
lipid digestionGO:004424130.017
lateral line system developmentGO:0048925760.017
regulation of cytokine productionGO:000181730.017
growthGO:00400071740.017
regulation of response to extracellular stimulusGO:003210410.017
regulation of reactive oxygen species metabolic processGO:200037720.017
negative regulation of rna metabolic processGO:0051253480.017
response to lipidGO:0033993600.017
negative regulation of cellular biosynthetic processGO:0031327550.017
positive regulation of secretionGO:005104710.017
cell matrix adhesionGO:000716040.017
response to endogenous stimulusGO:0009719830.017
regulation of phGO:000688530.017
cellular component assemblyGO:00226071700.017
response to corticosteroidGO:003196010.017
maintenance of locationGO:005123540.017
cellular response to biotic stimulusGO:007121630.017
cardiac atrium developmentGO:000323040.017
ear morphogenesisGO:0042471640.017
nucleic acid metabolic processGO:00903042440.017
regulation of cell cycleGO:0051726520.017
b cell differentiationGO:003018310.017
cellular response to extracellular stimulusGO:003166820.016
response to estrogenGO:0043627270.016
positive regulation of developmental processGO:0051094500.016
cell aggregationGO:009874330.016
rhombomere 6 developmentGO:002157240.016
negative regulation of protein phosphorylationGO:000193340.016
regulation of gastrulationGO:0010470240.016
nucleobase containing compound biosynthetic processGO:00346542050.016
epiboly involved in gastrulation with mouth forming secondGO:0055113350.016
female sex differentiationGO:004666040.016
response to oxygen containing compoundGO:1901700550.016
muscle structure developmentGO:00610611960.016
fin morphogenesisGO:0033334530.016
guanosine containing compound metabolic processGO:190106840.016
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082340.016
cell fate specification involved in pattern specificationGO:006057330.016
cellular response to steroid hormone stimulusGO:0071383310.016
notochord developmentGO:0030903540.016
endothelial cell differentiationGO:0045446200.016
embryonic digestive tract developmentGO:004856640.016
regulation of muscle contractionGO:000693730.016
catechol containing compound metabolic processGO:000971220.016
regulation of circadian sleep wake cycleGO:004274910.016
negative regulation of nitrogen compound metabolic processGO:0051172590.015
positive regulation of blood circulationGO:190352420.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
hepatocyte proliferationGO:007257420.015
regulation of apoptotic processGO:0042981980.015
cellular response to endogenous stimulusGO:0071495680.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
fin developmentGO:0033333770.015
cellular response to xenobiotic stimulusGO:0071466350.015
reactive oxygen species metabolic processGO:007259360.015
phosphate containing compound metabolic processGO:00067961080.015
negative regulation of feeding behaviorGO:200025220.015
sleepGO:003043110.015
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.015
regulation of bmp signaling pathwayGO:0030510390.015
negative regulation of cellular metabolic processGO:0031324770.015
acylglycerol homeostasisGO:005509020.014
epithelial cell morphogenesisGO:000338220.014
epithelial tube morphogenesisGO:00605621480.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.014
regulation of cell deathGO:00109411030.014
anterior commissure morphogenesisGO:002196030.014
axon developmentGO:00615641660.014
lipid catabolic processGO:001604240.014
protein localizationGO:0008104400.014
response to biotic stimulusGO:0009607970.014
single organism reproductive processGO:0044702400.014
positive regulation of gtpase activityGO:004354710.014
embryonic appendage morphogenesisGO:0035113300.014
single organism localizationGO:19025782250.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.014
cellular aromatic compound metabolic processGO:00067252950.014
macromolecule localizationGO:0033036540.014
cellular response to estradiol stimulusGO:007139210.014
modification dependent macromolecule catabolic processGO:004363230.014
regulation of nucleocytoplasmic transportGO:004682220.014
negative regulation of heart contractionGO:004582220.014
circadian sleep wake cycleGO:004274520.014
positive regulation of metabolic processGO:00098931080.014
regulation of blood vessel sizeGO:005088020.014
cellular response to stressGO:0033554620.014
bone remodelingGO:004684920.014
system processGO:00030081850.014
negative regulation of intracellular signal transductionGO:1902532220.014
signal transduction in absence of ligandGO:003803410.014
mesenchymal cell developmentGO:0014031780.014
brain developmentGO:00074202930.014
regulation of rna biosynthetic processGO:20011412130.014
guanosine containing compound catabolic processGO:190106920.013
skeletal system morphogenesisGO:00487051020.013
determination of heart left right asymmetryGO:00613711170.013
regulation of protein metabolic processGO:0051246560.013
somite developmentGO:0061053960.013
post anal tail morphogenesisGO:0036342190.013
glial cell differentiationGO:0010001420.013
regulation of inflammatory responseGO:005072720.013
cellular protein metabolic processGO:00442671290.013
blood coagulationGO:0007596120.013
hepaticobiliary system developmentGO:0061008980.013
head developmentGO:00603223030.013
regulation of response to nutrient levelsGO:003210710.013
cellular component morphogenesisGO:00329893360.013
membrane invaginationGO:001032410.013
positive regulation of rna metabolic processGO:0051254590.013
vitamin a biosynthetic processGO:003523810.013
glial cell migrationGO:000834730.013
muscle organ developmentGO:00075171010.013
morphogenesis of embryonic epitheliumGO:0016331300.013
protein modification processGO:00362111000.013
positive regulation of secretion by cellGO:190353210.013
cerebellar granule cell differentiationGO:002170730.013
regulation of response to oxidative stressGO:190288220.012
meiotic chromosome segregationGO:004513230.012
central nervous system neuron differentiationGO:0021953740.012
regulation of tube sizeGO:003515020.012
embryonic hemopoiesisGO:0035162530.012
positive regulation of cellular processGO:00485222010.012
exocrine system developmentGO:0035272280.012
organic substance biosynthetic processGO:19015762890.012
specification of axis polarityGO:006500140.012
fin regenerationGO:0031101510.012
neurological system processGO:0050877620.012
cellular response to fibroblast growth factor stimulusGO:0044344220.012
regulation of heart growthGO:006042020.012
wnt signaling pathwayGO:0016055800.012
centrosome organizationGO:005129710.012
zymogen activationGO:003163830.012
proteolysis involved in cellular protein catabolic processGO:005160330.012
negative regulation of rna biosynthetic processGO:1902679450.012
regulation of erk1 and erk2 cascadeGO:007037240.012
rhombomere morphogenesisGO:0021593170.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
endocardium formationGO:006021410.012
ectodermal placode morphogenesisGO:0071697320.012
cellular response to growth factor stimulusGO:0071363390.012
positive regulation of protein complex assemblyGO:003133420.012
positive regulation of nucleobase containing compound metabolic processGO:0045935690.012
response to extracellular stimulusGO:0009991100.012
endocrine processGO:005088620.012
response to foodGO:003209410.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.011
regulation of wnt signaling pathwayGO:0030111530.011
female gonad developmentGO:000858540.011
inositol lipid mediated signalingGO:004801720.011
negative regulation of secretion by cellGO:190353120.011
circulatory system processGO:0003013870.011
regulation of nucleotide catabolic processGO:003081120.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
regulation of synaptic plasticityGO:004816710.011
cilium morphogenesisGO:0060271850.011
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.011

gcga disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.092
endocrine system diseaseDOID:2800.041
acquired metabolic diseaseDOID:006015800.040
carbohydrate metabolism diseaseDOID:005001300.040
type 2 diabetes mellitusDOID:935200.040
disease of metabolismDOID:001466700.040
glucose metabolism diseaseDOID:419400.040
diabetes mellitusDOID:935100.040
cardiovascular system diseaseDOID:128700.023
musculoskeletal system diseaseDOID:1700.020
organ system cancerDOID:005068600.019
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011