Danio rerio

0 known processes

her2

hairy-related 2

(Aliases: HER-2)

her2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of macromolecule metabolic processGO:00602553170.276
epidermal cell fate specificationGO:000995740.161
embryo development ending in birth or egg hatchingGO:00097922710.154
cellular nitrogen compound metabolic processGO:00346412900.151
cellular component morphogenesisGO:00329893360.148
nitrogen compound metabolic processGO:00068073190.146
negative regulation of biological processGO:00485193040.138
nucleic acid templated transcriptionGO:00976591810.135
larval developmentGO:000216420.134
gene expressionGO:00104672520.133
regulation of macromolecule biosynthetic processGO:00105562250.132
cellular macromolecule metabolic processGO:00442603910.128
regulation of cellular macromolecule biosynthetic processGO:20001122220.127
cellular macromolecule biosynthetic processGO:00346452240.123
regulation of gene expressionGO:00104682650.122
neuron developmentGO:00486662620.120
regulation of metabolic processGO:00192223590.112
positive regulation of neural precursor cell proliferationGO:200017910.108
regulation of cellular metabolic processGO:00313233200.106
organic cyclic compound metabolic processGO:19013603010.102
generation of neuronsGO:00486993850.101
regulation of stem cell proliferationGO:007209120.099
organelle organizationGO:00069962270.099
chordate embryonic developmentGO:00430092710.097
positive regulation of stem cell proliferationGO:200064810.096
organic substance biosynthetic processGO:19015762890.095
regulation of biosynthetic processGO:00098892500.093
macromolecule biosynthetic processGO:00090592270.091
locomotionGO:00400113130.087
rna metabolic processGO:00160702190.080
cellular aromatic compound metabolic processGO:00067252950.078
cellular biosynthetic processGO:00442492860.077
lens fiber cell morphogenesisGO:007030930.077
neuroblast proliferationGO:000740520.077
cell morphogenesisGO:00009022890.077
stem cell proliferationGO:007208940.071
regulation of multicellular organismal processGO:00512392770.071
positive regulation of biological processGO:00485182530.070
cell migrationGO:00164772370.069
nucleobase containing compound metabolic processGO:00061392740.069
biosynthetic processGO:00090582940.065
glial cell migrationGO:000834730.065
morphogenesis of an epitheliumGO:00020093330.065
glial cell fate specificationGO:002178040.064
regulation of primary metabolic processGO:00800903110.062
regulation of neural precursor cell proliferationGO:200017730.061
cell motilityGO:00488702440.059
regulation of nucleic acid templated transcriptionGO:19035062130.059
eye morphogenesisGO:00485921440.057
camera type eye developmentGO:00430102220.056
regulation of nitrogen compound metabolic processGO:00511712510.056
regulation of multicellular organism growthGO:004001440.056
oligodendrocyte cell fate specificationGO:002177840.055
astrocyte differentiationGO:004870810.055
regulation of rna metabolic processGO:00512522240.055
nucleic acid metabolic processGO:00903042440.055
heterocycle metabolic processGO:00464832900.054
regulation of cellular biosynthetic processGO:00313262450.054
regulation of stem cell differentiationGO:200073640.053
regulation of epithelial cell proliferationGO:005067830.052
negative regulation of cellular processGO:00485232830.051
rna biosynthetic processGO:00327741810.051
cellular component movementGO:00069283350.050
positive regulation of map kinase activityGO:004340630.050
positive regulation of cellular processGO:00485222010.050
cellular amino acid metabolic processGO:000652070.049
regulation of dendrite developmentGO:005077330.049
central nervous system developmentGO:00074173870.048
transcription dna templatedGO:00063511810.048
cellular amine metabolic processGO:004410620.048
heterocycle biosynthetic processGO:00181302150.047
cell fate specificationGO:0001708680.046
embryonic organ developmentGO:00485683810.046
regulation of response to stimulusGO:00485832690.046
single organism metabolic processGO:00447102170.045
keratinocyte differentiationGO:003021600.045
oxoacid metabolic processGO:0043436310.045
amine metabolic processGO:000930820.044
cilium assemblyGO:0042384580.044
regulation of nucleobase containing compound metabolic processGO:00192192500.044
regulation of rna biosynthetic processGO:20011412130.043
digestive tract developmentGO:00485652650.043
system processGO:00030081850.043
organic cyclic compound biosynthetic processGO:19013622230.042
signal transductionGO:00071654550.042
embryonic organ morphogenesisGO:00485622740.041
negative regulation of gliogenesisGO:001401410.041
response to amino acidGO:004320020.041
meiotic nuclear divisionGO:000712640.041
regulation of cellular amine metabolic processGO:003323800.040
ventral spinal cord interneuron differentiationGO:0021514120.040
neuron differentiationGO:00301823530.040
aromatic compound biosynthetic processGO:00194382170.040
agingGO:000756820.040
regionalizationGO:00030022740.039
auditory receptor cell fate determinationGO:004266820.039
cardiac chamber formationGO:000320740.039
cellular protein modification processGO:00064641000.039
axon developmentGO:00615641660.038
regulation of cellular amino acid metabolic processGO:000652100.038
regulation of developmental processGO:00507932470.037
cellular ketone metabolic processGO:0042180110.037
nucleobase containing compound biosynthetic processGO:00346542050.037
eye developmentGO:00016542770.035
digestive tract morphogenesisGO:00485462310.035
cell surface receptor signaling pathwayGO:00071663250.035
embryonic heart tube developmentGO:00350501330.035
camera type eye morphogenesisGO:00485931080.035
digestive system developmentGO:00551232890.035
cell projection morphogenesisGO:00488582440.035
negative regulation of protein phosphorylationGO:000193340.034
single organism organelle organizationGO:19025891990.034
skin developmentGO:0043588540.034
epithelial cell differentiationGO:00308551160.034
olfactory bulb developmentGO:002177240.033
ventral spinal cord interneuron fate commitmentGO:006057930.033
regulation of dendrite morphogenesisGO:004881430.033
mesenchymal cell differentiationGO:0048762870.032
localization of cellGO:00516742440.032
cellular protein metabolic processGO:00442671290.031
regulation of anatomical structure morphogenesisGO:00226031300.031
organic acid metabolic processGO:0006082310.031
carboxylic acid metabolic processGO:0019752220.031
cell proliferation in forebrainGO:002184630.031
negative regulation of stem cell differentiationGO:200073720.030
positive regulation of cellular amine metabolic processGO:003324000.030
immune system processGO:00023762410.030
positive regulation of notch signaling pathwayGO:004574730.030
peripheral nervous system developmentGO:0007422550.030
cellular nitrogen compound biosynthetic processGO:00442712180.030
establishment of localizationGO:00512342440.030
brain developmentGO:00074202930.029
inner ear receptor cell fate commitmentGO:006012040.029
protein metabolic processGO:00195381830.029
phosphate containing compound metabolic processGO:00067961080.029
regulation of multicellular organismal developmentGO:20000262230.029
regulation of dna replicationGO:000627530.029
negative regulation of cell developmentGO:0010721260.029
response to stressGO:00069502630.029
protein modification processGO:00362111000.029
regulation of bindingGO:005109830.028
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.028
cell part morphogenesisGO:00329902460.028
cell fate commitmentGO:0045165990.028
cell morphogenesis involved in differentiationGO:00009041950.028
neuron fate determinationGO:004866420.027
positive regulation of epithelial cell differentiationGO:003085820.027
regulation of jak stat cascadeGO:004642530.027
lens development in camera type eyeGO:0002088220.027
axon ensheathment in central nervous systemGO:003229120.027
regulation of cellular ketone metabolic processGO:001056570.027
endocrine pancreas developmentGO:0031018270.027
stem cell differentiationGO:00488631170.027
neuroblast fate determinationGO:000740010.027
neuronal stem cell maintenanceGO:009715020.027
neuron projection developmentGO:00311751800.026
determination of bilateral symmetryGO:00098552040.026
cell projection organizationGO:00300302840.026
central nervous system myelin formationGO:003228910.026
positive regulation of cellular amino acid metabolic processGO:004576400.026
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.026
response to woundingGO:00096111160.026
positive regulation of transportGO:005105020.025
response to chemicalGO:00422213200.025
negative regulation of epithelial cell proliferationGO:005068010.025
stem cell maintenanceGO:001982740.025
negative regulation of histone modificationGO:003105710.025
phagocytosisGO:000690930.025
cell fate specification involved in pattern specificationGO:006057330.025
neural precursor cell proliferationGO:0061351200.025
head developmentGO:00603223030.025
central nervous system myelinationGO:002201020.024
organonitrogen compound metabolic processGO:1901564740.024
anterior posterior pattern specificationGO:00099521520.024
neuroblast fate commitmentGO:001401710.024
embryonic skeletal system developmentGO:0048706970.024
multicellular organism growthGO:003526440.024
regulation of cell differentiationGO:00455951420.024
exocytosisGO:000688710.024
guanosine containing compound metabolic processGO:190106840.023
lens fiber cell developmentGO:007030730.023
positive regulation of secretionGO:005104710.023
regulation of signal transductionGO:00099662250.023
positive regulation of epithelial cell proliferationGO:005067910.023
oocyte maturationGO:000155640.023
regulation of peptidyl tyrosine phosphorylationGO:005073010.023
maintenance of locationGO:005123540.023
macromolecule modificationGO:00434121110.023
cellular amide metabolic processGO:004360340.022
regulation of gtp catabolic processGO:003312420.022
regulation of endothelial cell differentiationGO:004560130.022
blood vessel morphogenesisGO:00485142160.022
phosphorus metabolic processGO:00067931090.022
negative regulation of biosynthetic processGO:0009890550.022
stem cell fate determinationGO:004886710.022
sister chromatid cohesionGO:000706220.022
multicellular organismal signalingGO:0035637220.022
regulation of transcription dna templatedGO:00063552130.022
negative regulation of macromolecule metabolic processGO:0010605760.022
determination of left right symmetryGO:00073681790.021
regulation of signalingGO:00230512350.021
regulation of histone methylationGO:003106030.021
photoreceptor cell differentiationGO:0046530550.021
embryonic heart tube morphogenesisGO:00031431080.021
negative regulation of macromolecule biosynthetic processGO:0010558480.021
blood vessel developmentGO:00015682460.021
atp catabolic processGO:000620040.021
epidermis developmentGO:0008544480.021
neuroblast differentiationGO:001401610.021
axonogenesisGO:00074091520.021
gtp metabolic processGO:004603940.020
cellular component biogenesisGO:00440851780.020
positive regulation of cell cycleGO:004578730.020
cell cell recognitionGO:000998810.020
heart developmentGO:00075073130.020
positive regulation of macromolecule metabolic processGO:0010604930.020
medulla oblongata developmentGO:002155040.020
heart morphogenesisGO:00030071560.020
regulation of dna templated transcription in response to stressGO:004362000.020
auditory receptor cell fate commitmentGO:000991240.020
regulation of cardiac chamber formationGO:190121020.020
neuron projection morphogenesisGO:00488121610.020
developmental growthGO:00485891660.020
small molecule metabolic processGO:0044281770.020
dna methylation on cytosineGO:003277630.020
regulation of cell cycleGO:0051726520.020
regulation of cell developmentGO:00602841000.020
compound eye developmentGO:004874920.020
polarized epithelial cell differentiationGO:003085940.019
endocrine system developmentGO:0035270650.019
lipid storageGO:001991510.019
neuron neuron synaptic transmissionGO:000727010.019
gtp catabolic processGO:000618420.019
cilium morphogenesisGO:0060271850.019
rna localizationGO:000640340.019
cell morphogenesis involved in neuron differentiationGO:00486671630.019
forebrain developmentGO:0030900960.019
regulation of cell communicationGO:00106462320.018
striated muscle tissue developmentGO:00147061100.018
g1 s transition of mitotic cell cycleGO:000008210.018
muscle structure developmentGO:00610611960.018
ribonucleoside monophosphate catabolic processGO:000915840.018
positive regulation of mesenchymal cell proliferationGO:000205310.018
positive regulation of developmental processGO:0051094500.018
regulation of epithelial to mesenchymal transitionGO:001071730.018
long chain fatty acid metabolic processGO:000167610.018
antimicrobial humoral responseGO:001973020.018
positive regulation of rna biosynthetic processGO:1902680570.018
oligodendrocyte differentiationGO:0048709230.018
defense response to fungusGO:005083220.017
lymphatic endothelial cell fate commitmentGO:006083810.017
photoreceptor cell developmentGO:0042461400.017
guanosine containing compound catabolic processGO:190106920.017
regulation of histone h3 k9 methylationGO:005157020.017
negative regulation of dna metabolic processGO:005105340.017
regulation of protein metabolic processGO:0051246560.017
negative regulation of nucleobase containing compound metabolic processGO:0045934590.017
phosphorylationGO:0016310690.017
regulation of purine nucleotide catabolic processGO:003312120.017
epidermal cell differentiationGO:0009913360.017
cardiocyte differentiationGO:0035051440.017
chromosome organizationGO:0051276310.017
pancreas developmentGO:0031016840.016
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.016
secondary metabolic processGO:001974830.016
positive regulation of endothelial cell differentiationGO:004560320.016
sensory organ morphogenesisGO:00905962000.016
transportGO:00068102200.016
septum transversum developmentGO:000334340.016
positive regulation of histone modificationGO:003105810.016
heart loopingGO:0001947940.016
fin morphogenesisGO:0033334530.016
protein phosphorylationGO:0006468470.016
forebrain neuron fate commitmentGO:002187710.016
synaptic growth at neuromuscular junctionGO:005112420.016
negative regulation of metabolic processGO:0009892860.016
epithelial tube morphogenesisGO:00605621480.016
negative regulation of cell differentiationGO:0045596460.016
gland developmentGO:00487321430.016
regulation of cytoplasmic transportGO:190364940.016
neuronal action potentialGO:0019228180.016
spinal cord developmentGO:0021510460.016
radial glial cell differentiationGO:006001920.016
response to external stimulusGO:00096052640.016
organelle fissionGO:0048285230.016
mesenchyme developmentGO:00604851270.015
wnt signaling pathwayGO:0016055800.015
regulation of production of molecular mediator of immune responseGO:000270010.015
positive regulation of stress activated mapk cascadeGO:003287430.015
regulation of transcription from rna polymerase ii promoterGO:00063571140.015
positive regulation of macromolecule biosynthetic processGO:0010557590.015
tube morphogenesisGO:00352393490.015
somitogenesisGO:0001756870.015
dna alkylationGO:000630580.015
regulation of neurogenesisGO:0050767870.015
regulation of cell activationGO:005086510.015
olfactory lobe developmentGO:002198840.014
response to external biotic stimulusGO:0043207970.014
negative regulation of epithelial cell migrationGO:001063310.014
anterior lateral line nerve developmentGO:004890940.014
cellular component assemblyGO:00226071700.014
dna templated transcription initiationGO:000635210.014
negative regulation of chromatin modificationGO:190330910.014
regulation of nucleoside metabolic processGO:000911820.014
developmental programmed cell deathGO:001062340.014
positive regulation of biosynthetic processGO:0009891680.014
negative regulation of myeloid cell differentiationGO:004563810.014
fin developmentGO:0033333770.014
negative regulation of neural precursor cell proliferationGO:200017810.014
regulation of immune system processGO:0002682340.014
endocardium morphogenesisGO:000316040.014
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.014
dna modificationGO:000630480.014
retina development in camera type eyeGO:00600411460.014
positive regulation of cytoskeleton organizationGO:005149530.014
positive regulation of immune effector processGO:000269930.013
regulation of reproductive processGO:200024140.013
cell cycleGO:0007049930.013
regulation of hematopoietic progenitor cell differentiationGO:190153210.013
protein dephosphorylationGO:000647030.013
regulation of biological qualityGO:00650082630.013
multicellular organismal response to stressGO:003355520.013
regulation of exocytosisGO:001715710.013
regulation of mesenchymal cell proliferationGO:001046410.013
pancreatic a cell developmentGO:000332220.013
definitive hemopoiesisGO:0060216180.013
hemopoiesisGO:00300971830.013
protein acylationGO:004354330.013
mesoderm developmentGO:0007498880.013
mitotic dna damage checkpointGO:004477340.013
myelinationGO:0042552180.013
regulation of nucleotide catabolic processGO:003081120.013
extracellular matrix assemblyGO:008502910.013
positive regulation of exocytosisGO:004592110.013
embryonic heart tube formationGO:000314410.013
regenerationGO:0031099910.013
female sex differentiationGO:004666040.013
negative regulation of chromosome organizationGO:200125110.013
hypochord developmentGO:005501630.013
histone h3 k4 methylationGO:005156820.013
transcription from rna polymerase ii promoterGO:0006366800.013
dorsal ventral pattern formationGO:00099531250.013
cell cycle g1 s phase transitionGO:004484310.013
positive regulation of jnk cascadeGO:004633030.013
regulation of photoreceptor cell differentiationGO:004653220.013
mitotic dna integrity checkpointGO:004477440.013
vasculature developmentGO:00019442780.013
neurological system processGO:0050877620.013
negative regulation of gene expressionGO:0010629650.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
regulation of circadian rhythmGO:004275240.012
cilium organizationGO:0044782710.012
sensory organ developmentGO:00074233930.012
notch signaling pathwayGO:0007219350.012
positive regulation of secretion by cellGO:190353210.012
myelin assemblyGO:003228810.012
regulation of cellular component organizationGO:0051128860.012
embryonic skeletal system morphogenesisGO:0048704930.012
regulation of neuron differentiationGO:0045664560.012
floor plate developmentGO:0033504150.012
fertilizationGO:000956630.012
production of molecular mediator of immune responseGO:000244020.012
neuron projection regenerationGO:0031102160.012
response to oxygen levelsGO:0070482250.012
retina layer formationGO:0010842240.012
locomotor rhythmGO:004547530.012
appendage developmentGO:0048736800.012
immunoglobulin productionGO:000237710.012
determination of heart left right asymmetryGO:00613711170.012
cellular response to stressGO:0033554620.012
negative regulation of cellular biosynthetic processGO:0031327550.012
negative regulation of histone methylationGO:003106110.012
negative regulation of signalingGO:0023057960.012
cell substrate adhesionGO:003158940.012
glial cell fate commitmentGO:002178160.012
lateral inhibitionGO:004633110.011
activation of mapk activityGO:000018730.011
skeletal system developmentGO:00015011810.011
locomotory behaviorGO:0007626340.011
cell differentiation in spinal cordGO:0021515400.011
positive regulation of gene expressionGO:0010628710.011
apoptotic process involved in developmentGO:190274220.011
oocyte anterior posterior axis specificationGO:000731440.011
negative regulation of endothelial cell migrationGO:001059610.011
specification of symmetryGO:00097992040.011
purine nucleoside monophosphate catabolic processGO:000912840.011
regulation of gtpase activityGO:004308720.011
cytoskeleton organizationGO:0007010960.011
negative regulation of response to stimulusGO:00485851040.011
long chain fatty acid transportGO:001590910.011
glial cell proliferationGO:001400940.011
trabecula morphogenesisGO:006138320.011
establishment of protein localization to organelleGO:007259440.011
lymphocyte proliferationGO:004665110.011
cellular response to organic substanceGO:00713101050.011
response to carbohydrateGO:000974330.011
intracellular signal transductionGO:0035556850.011
g2 m transition of mitotic cell cycleGO:000008640.011
peptidyl lysine acetylationGO:001839420.011
alternative mrna splicing via spliceosomeGO:000038010.011
cellular component assembly involved in morphogenesisGO:00109271070.011
negative regulation of dna replicationGO:000815620.011
internal protein amino acid acetylationGO:000647520.011
proepicardium developmentGO:000334240.011
regulation of molecular functionGO:0065009700.011
cell proliferationGO:0008283800.011
neuron projection guidanceGO:0097485860.011
immune system developmentGO:00025201910.011
peripheral nervous system neuron axonogenesisGO:0048936130.010
striated muscle cell differentiationGO:00511461290.010
response to organic substanceGO:00100331530.010
photoreceptor cell fate commitmentGO:004655210.010
cellular response to chemical stimulusGO:00708871570.010
multi organism processGO:00517041340.010
positive regulation of cellular metabolic processGO:0031325940.010
positive regulation of jak stat cascadeGO:004642720.010
cellular response to reactive oxygen speciesGO:003461420.010
positive regulation of multicellular organismal processGO:0051240520.010
water homeostasisGO:003010440.010
forebrain anterior posterior pattern specificationGO:002179730.010
ventral spinal cord interneuron specificationGO:002152130.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
regulation of membrane potentialGO:0042391230.010
dorsal spinal cord developmentGO:002151610.010
positive regulation of cellular component biogenesisGO:004408930.010
dna methylationGO:000630680.010
hepaticobiliary system developmentGO:0061008980.010

her2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
nervous system diseaseDOID:86300.017
eye and adnexa diseaseDOID:149200.016
sensory system diseaseDOID:005015500.016
eye diseaseDOID:561400.016
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.013
bone diseaseDOID:008000100.012
musculoskeletal system diseaseDOID:1700.012
connective tissue diseaseDOID:6500.012