Danio rerio

0 known processes

LOC100005454

Gig2-like protein DreK

LOC100005454 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
urea transmembrane transportGO:007191890.216
glycerol transportGO:001579370.181
fluid transportGO:0042044170.168
ion transmembrane transportGO:0034220910.156
ammonium transmembrane transportGO:007248820.146
inorganic ion transmembrane transportGO:0098660570.127
one carbon compound transportGO:0019755140.120
water transportGO:0006833150.116
signal transductionGO:00071654550.106
immune system processGO:00023762410.104
monovalent inorganic cation transportGO:0015672420.098
transportGO:00068102200.093
cell surface receptor signaling pathwayGO:00071663250.093
single organism transportGO:00447652060.079
larval developmentGO:000216420.076
carbon dioxide transmembrane transportGO:003537810.068
establishment of localizationGO:00512342440.065
positive regulation of cell cycleGO:004578730.065
g protein coupled receptor signaling pathwayGO:0007186740.060
response to glucocorticoidGO:005138410.058
sensory organ developmentGO:00074233930.056
ion transportGO:00068111140.055
response to stressGO:00069502630.055
defense response to other organismGO:0098542330.050
eye developmentGO:00016542770.050
transcription dna templatedGO:00063511810.050
agingGO:000756820.049
rna metabolic processGO:00160702190.047
multicellular organism growthGO:003526440.046
nucleocytoplasmic transportGO:000691340.045
positive regulation of transportGO:005105020.045
response to external biotic stimulusGO:0043207970.045
single organism localizationGO:19025782250.044
inorganic anion transportGO:0015698250.042
carbon dioxide transportGO:001567030.040
nuclear transportGO:005116940.040
response to organic substanceGO:00100331530.039
homeostatic processGO:00425921420.039
polyol transportGO:001579170.039
cellular macromolecule biosynthetic processGO:00346452240.037
central nervous system developmentGO:00074173870.036
regulation of multicellular organism growthGO:004001440.036
regulation of metal ion transportGO:001095940.036
transmembrane transportGO:00550851200.035
regulation of gene expressionGO:00104682650.034
regulation of cytokine productionGO:000181730.034
regulation of multicellular organismal processGO:00512392770.034
establishment of protein localization to organelleGO:007259440.033
urea transportGO:0015840110.032
response to chemicalGO:00422213200.032
phagocytosisGO:000690930.032
cellular amine metabolic processGO:004410620.032
camera type eye developmentGO:00430102220.031
morphogenesis of an epitheliumGO:00020093330.031
lipid homeostasisGO:005508830.031
positive regulation of lymphocyte mediated immunityGO:000270810.030
response to carbohydrateGO:000974330.030
regulation of response to stimulusGO:00485832690.030
regulation of nucleobase containing compound metabolic processGO:00192192500.029
maintenance of locationGO:005123540.029
regulation of rna biosynthetic processGO:20011412130.029
positive regulation of cellular catabolic processGO:003133130.029
cation transmembrane transportGO:0098655650.028
response to external stimulusGO:00096052640.028
multi organism processGO:00517041340.028
head developmentGO:00603223030.028
nucleic acid templated transcriptionGO:00976591810.028
lipid storageGO:001991510.027
tube morphogenesisGO:00352393490.027
regulation of protein catabolic processGO:004217610.027
protein targeting to nucleusGO:004474430.027
cellular response to chemical stimulusGO:00708871570.026
cellular nitrogen compound metabolic processGO:00346412900.026
brain developmentGO:00074202930.026
heterocycle biosynthetic processGO:00181302150.026
rna biosynthetic processGO:00327741810.026
nuclear importGO:005117030.026
meiotic nuclear divisionGO:000712640.025
chordate embryonic developmentGO:00430092710.025
cellular response to external stimulusGO:007149620.025
regulation of cellular amine metabolic processGO:003323800.025
organelle organizationGO:00069962270.025
regulation of primary metabolic processGO:00800903110.025
heterocycle metabolic processGO:00464832900.024
regulation of cytoplasmic transportGO:190364940.024
immune responseGO:0006955280.024
stem cell proliferationGO:007208940.024
regulation of bindingGO:005109830.024
specification of symmetryGO:00097992040.024
response to corticosteroidGO:003196010.023
cellular response to extracellular stimulusGO:003166820.023
digestive system developmentGO:00551232890.023
protein acetylationGO:000647320.023
response to glucoseGO:000974930.023
negative regulation of cytokine productionGO:000181810.023
lipid catabolic processGO:001604240.023
regulation of biosynthetic processGO:00098892500.023
gtp metabolic processGO:004603940.023
regulation of nucleotide catabolic processGO:003081120.023
glucose homeostasisGO:004259310.022
cellular response to organic substanceGO:00713101050.022
lymphocyte proliferationGO:004665110.022
biosynthetic processGO:00090582940.022
cellular response to starvationGO:000926710.022
hormone secretionGO:004687920.022
regulation of transcription dna templatedGO:00063552130.022
regulation of cellular amino acid metabolic processGO:000652100.022
protein import into nucleusGO:000660630.022
regulation of establishment of protein localizationGO:007020140.022
protein localization to nucleusGO:003450430.022
nucleobase containing compound metabolic processGO:00061392740.022
positive regulation of nitrogen compound metabolic processGO:0051173690.022
response to nutrientGO:000758430.022
positive regulation of catabolic processGO:000989640.022
negative regulation of dna metabolic processGO:005105340.022
response to hexoseGO:000974630.022
cellular ketone metabolic processGO:0042180110.021
locomotionGO:00400113130.021
mononuclear cell proliferationGO:003294310.021
meiotic cell cycle processGO:190304630.021
positive regulation of immune effector processGO:000269930.021
regulation of signal transductionGO:00099662250.021
regulation of macromolecule biosynthetic processGO:00105562250.021
autophagyGO:000691440.021
regulation of nitrogen compound metabolic processGO:00511712510.021
positive regulation of cytokine productionGO:000181920.021
gene expressionGO:00104672520.021
cellular macromolecule metabolic processGO:00442603910.020
regulation of cell communicationGO:00106462320.020
renal absorptionGO:007029310.020
cation transportGO:0006812810.020
regulation of cell activationGO:005086510.020
stem cell maintenanceGO:001982740.020
organic cyclic compound biosynthetic processGO:19013622230.020
regulation of nucleic acid templated transcriptionGO:19035062130.020
ovulation cycle processGO:002260220.020
single organism nuclear importGO:190259330.020
regulation of purine nucleotide catabolic processGO:003312120.020
nucleic acid metabolic processGO:00903042440.020
cellular nitrogen compound biosynthetic processGO:00442712180.020
organic cyclic compound metabolic processGO:19013603010.020
regulation of reproductive processGO:200024140.020
organic substance transportGO:0071702580.020
defense response to bacteriumGO:0042742220.019
regulation of signalingGO:00230512350.019
regulation of cellular metabolic processGO:00313233200.019
regulation of phGO:000688530.019
negative regulation of catabolic processGO:000989530.019
regulation of protein complex assemblyGO:004325430.019
regulation of inflammatory responseGO:005072720.019
regulation of cellular ketone metabolic processGO:001056570.019
regulation of nucleoside metabolic processGO:000911820.019
water homeostasisGO:003010440.019
carbohydrate transportGO:0008643130.019
regulation of developmental processGO:00507932470.019
digestive tract developmentGO:00485652650.019
inorganic cation transmembrane transportGO:0098662500.019
regulation of metabolic processGO:00192223590.019
organic hydroxy compound transportGO:0015850140.019
gas transportGO:001566930.019
negative regulation of nuclear divisionGO:005178430.019
response to monosaccharideGO:003428430.019
regulation of cellular biosynthetic processGO:00313262450.019
amine metabolic processGO:000930820.018
negative regulation of biological processGO:00485193040.018
nitrogen compound metabolic processGO:00068073190.018
positive regulation of secretionGO:005104710.018
aromatic compound biosynthetic processGO:00194382170.018
protein acylationGO:004354330.018
response to other organismGO:0051707970.018
endocrine processGO:005088620.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.018
defense responseGO:0006952470.018
regulation of macromolecule metabolic processGO:00602553170.018
response to ketoneGO:190165410.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
positive regulation of cell activationGO:005086710.018
regulation of autophagyGO:001050630.018
regulation of nucleocytoplasmic transportGO:004682220.018
cellular response to lipopolysaccharideGO:007122230.018
negative regulation of protein phosphorylationGO:000193340.018
long chain fatty acid metabolic processGO:000167610.018
vasculature developmentGO:00019442780.018
positive regulation of biological processGO:00485182530.017
tissue remodelingGO:004877140.017
proteolysis involved in cellular protein catabolic processGO:005160330.017
regulation of protein transportGO:005122330.017
positive regulation of leukocyte mediated immunityGO:000270510.017
regulation of response to nutrient levelsGO:003210710.017
regulation of transporter activityGO:003240920.017
hemopoiesisGO:00300971830.017
regulation of cell killingGO:003134120.017
cellular component biogenesisGO:00440851780.017
regulation of cellular macromolecule biosynthetic processGO:20001122220.017
cellular amino acid metabolic processGO:000652070.017
developmental growthGO:00485891660.017
enzyme linked receptor protein signaling pathwayGO:00071671060.017
regulation of intracellular protein transportGO:003315730.017
b cell activationGO:004211320.017
sensory organ morphogenesisGO:00905962000.017
leukocyte proliferationGO:007066110.017
mitochondrion organizationGO:000700540.017
protein metabolic processGO:00195381830.017
cellular component assemblyGO:00226071700.016
protein importGO:001703830.016
neuron neuron synaptic transmissionGO:000727010.016
regulation of production of molecular mediator of immune responseGO:000270010.016
response to bacteriumGO:0009617580.016
regionalizationGO:00030022740.016
carbohydrate homeostasisGO:003350010.016
digestive tract morphogenesisGO:00485462310.016
peptidyl lysine acetylationGO:001839420.016
guanosine containing compound metabolic processGO:190106840.016
neuromast developmentGO:0048884460.016
somitogenesisGO:0001756870.016
female gonad developmentGO:000858540.016
anion transportGO:0006820380.016
regulation of dna replicationGO:000627530.016
positive regulation of secretion by cellGO:190353210.016
adult behaviorGO:003053420.016
embryo development ending in birth or egg hatchingGO:00097922710.016
multicellular organismal water homeostasisGO:005089110.016
regulation of hormone secretionGO:004688320.016
regulation of biological qualityGO:00650082630.016
positive regulation of cellular metabolic processGO:0031325940.016
negative regulation of cellular processGO:00485232830.016
retina development in camera type eyeGO:00600411460.016
protein secretionGO:000930610.016
positive regulation of cell divisionGO:005178120.016
positive regulation of cellular component biogenesisGO:004408930.016
negative regulation of gene expressionGO:0010629650.016
spermatid differentiationGO:004851520.016
morphogenesis of an epithelial sheetGO:0002011490.016
oxoacid metabolic processGO:0043436310.015
small molecule catabolic processGO:004428230.015
modification dependent macromolecule catabolic processGO:004363230.015
negative regulation of defense responseGO:003134820.015
regulation of tube sizeGO:003515020.015
response to vitaminGO:003327330.015
protein heterooligomerizationGO:005129110.015
negative regulation of nitrogen compound metabolic processGO:0051172590.015
regulation of blood vessel sizeGO:005088020.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.015
establishment of endothelial barrierGO:006102830.015
regulation of systemic arterial blood pressureGO:000307310.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.015
internal peptidyl lysine acetylationGO:001839320.015
regulation of protein localization to nucleusGO:190018020.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
response to topologically incorrect proteinGO:003596620.015
positive regulation of gene expressionGO:0010628710.015
regulation of sodium ion transportGO:000202820.015
internal protein amino acid acetylationGO:000647520.015
nucleobase containing compound biosynthetic processGO:00346542050.015
somatic cell dna recombinationGO:001644410.015
positive regulation of transcription dna templatedGO:0045893570.015
regulation of rna metabolic processGO:00512522240.015
ubiquitin dependent protein catabolic processGO:000651130.015
fatty acid transportGO:001590810.015
gtp catabolic processGO:000618420.015
regulation of response to extracellular stimulusGO:003210410.014
somite developmentGO:0061053960.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
stem cell divisionGO:001714510.014
positive regulation of rna metabolic processGO:0051254590.014
single organism organelle organizationGO:19025891990.014
response to woundingGO:00096111160.014
epibolyGO:0090504410.014
cellular response to light stimulusGO:007148240.014
cellular response to nutrient levelsGO:003166920.014
regulation of protein import into nucleusGO:004230620.014
regulation of gtpase activityGO:004308720.014
guanosine containing compound catabolic processGO:190106920.014
photoreceptor cell fate commitmentGO:004655210.014
b cell mediated immunityGO:001972430.014
regulation of blood pressureGO:000821710.014
positive regulation of blood circulationGO:190352420.014
positive regulation of nucleotide catabolic processGO:003081310.014
regulation of organ growthGO:004662030.014
positive regulation of cell killingGO:003134320.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
cellular aromatic compound metabolic processGO:00067252950.014
somatic muscle developmentGO:000752540.014
cell migrationGO:00164772370.014
cellular lipid catabolic processGO:004424230.014
positive regulation of gtpase activityGO:004354710.014
atp catabolic processGO:000620040.014
epithelial tube morphogenesisGO:00605621480.014
positive regulation of macromolecule metabolic processGO:0010604930.013
system processGO:00030081850.013
phagocytosis engulfmentGO:000691110.013
female sex differentiationGO:004666040.013
ovulation cycleGO:004269820.013
regulation of stem cell proliferationGO:007209120.013
macroautophagyGO:001623610.013
positive regulation of myeloid cell differentiationGO:004563920.013
gastrulationGO:00073692080.013
positive regulation of dna metabolic processGO:005105410.013
modification dependent protein catabolic processGO:001994130.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
organic acid metabolic processGO:0006082310.013
cellular response to endogenous stimulusGO:0071495680.013
membrane invaginationGO:001032410.013
regulation of ion transmembrane transporter activityGO:003241220.013
regulation of leukocyte mediated immunityGO:000270310.013
macromolecule biosynthetic processGO:00090592270.013
organic substance biosynthetic processGO:19015762890.013
cellular protein metabolic processGO:00442671290.013
negative regulation of cellular catabolic processGO:003133030.013
carboxylic acid metabolic processGO:0019752220.013
regulation of reactive oxygen species metabolic processGO:200037720.013
insulin like growth factor receptor signaling pathwayGO:004800940.013
positive regulation of cellular processGO:00485222010.013
positive regulation of reproductive processGO:200024320.013
negative regulation of metabolic processGO:0009892860.013
single organism metabolic processGO:00447102170.013
regulation of gtp catabolic processGO:003312420.013
phosphorus metabolic processGO:00067931090.013
cellular protein modification processGO:00064641000.013
sex determinationGO:000753010.013
embryonic organ developmentGO:00485683810.013
positive regulation of chromosome organizationGO:200125210.013
cellular response to biotic stimulusGO:007121630.013
immunoglobulin mediated immune responseGO:001606430.013
organic acid catabolic processGO:001605430.013
cellular protein catabolic processGO:004425740.013
spermatid developmentGO:000728620.012
development of primary female sexual characteristicsGO:004654540.012
cellular monovalent inorganic cation homeostasisGO:003000420.012
very long chain fatty acid metabolic processGO:000003840.012
peptide transportGO:001583310.012
intracellular signal transductionGO:0035556850.012
long chain fatty acid transportGO:001590910.012
cell morphogenesisGO:00009022890.012
production of molecular mediator of immune responseGO:000244020.012
positive regulation of gtp catabolic processGO:003312610.012
camera type eye morphogenesisGO:00485931080.012
regulation of protein targetingGO:190353320.012
cellular response to radiationGO:007147840.012
blood vessel developmentGO:00015682460.012
ear developmentGO:00435831270.012
regulation of transmembrane transporter activityGO:002289820.012
negative regulation of protein kinase activityGO:000646940.012
urogenital system developmentGO:0001655970.012
cellular response to hormone stimulusGO:0032870390.012
regulation of multicellular organismal developmentGO:20000262230.012
epiboly involved in gastrulation with mouth forming secondGO:0055113350.012
regulation of cellular phGO:003064110.012
dorsal ventral pattern formationGO:00099531250.012
positive regulation of histone modificationGO:003105810.012
regulation of p38mapk cascadeGO:190074410.012
single fertilizationGO:000733830.012
leukocyte mediated cytotoxicityGO:000190910.012
determination of left right symmetryGO:00073681790.011
interspecies interaction between organismsGO:004441940.011
small molecule metabolic processGO:0044281770.011
anterior posterior pattern specificationGO:00099521520.011
heart developmentGO:00075073130.011
positive regulation of neuron apoptotic processGO:004352510.011
regulation of wound healingGO:006104120.011
phosphatidylinositol mediated signalingGO:004801520.011
positive regulation of leukocyte mediated cytotoxicityGO:000191210.011
immune system developmentGO:00025201910.011
negative regulation of protein transportGO:005122430.011
regulation of growth rateGO:004000910.011
response to uvGO:000941130.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
negative regulation of protein complex assemblyGO:003133310.011
cellular carbohydrate metabolic processGO:004426240.011
amide transportGO:0042886120.011
regulation of protein ubiquitinationGO:003139630.011
embryonic organ morphogenesisGO:00485622740.011
regulation of intracellular phGO:005145310.011
response to biotic stimulusGO:0009607970.011
phosphatidylinositol 3 kinase signalingGO:001406520.011
response to alkaloidGO:004327920.011
hormone transportGO:000991420.011
modulation by virus of host morphology or physiologyGO:001904810.011
growthGO:00400071740.011
negative regulation of kinase activityGO:003367340.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
cellular response to molecule of bacterial originGO:007121930.011
invagination involved in gastrulation with mouth forming secondGO:005510910.011
regulation of protein bindingGO:004339330.011
negative regulation of chromosome organizationGO:200125110.011
rna localizationGO:000640340.011
positive regulation of cellular biosynthetic processGO:0031328680.011
multicellular organismal metabolic processGO:004423620.011
p38mapk cascadeGO:003806610.011
regulation of cellular protein catabolic processGO:190336210.011
positive regulation of inflammatory responseGO:005072910.011
immunoglobulin productionGO:000237710.011
regulation of natural killer cell mediated immunityGO:000271510.011
pyruvate metabolic processGO:000609010.011
macromolecule modificationGO:00434121110.011
regulation of neural precursor cell proliferationGO:200017730.010
regulation of epithelial cell proliferationGO:005067830.010
inositol lipid mediated signalingGO:004801720.010
negative regulation of signal transductionGO:0009968940.010
cellular response to organic cyclic compoundGO:0071407380.010
negative regulation of nucleocytoplasmic transportGO:004682320.010
endosomal transportGO:001619720.010
negative regulation of intracellular transportGO:003238730.010
negative regulation of multi organism processGO:004390130.010
transcription from rna polymerase ii promoterGO:0006366800.010
inner ear developmentGO:00488391260.010
response to endogenous stimulusGO:0009719830.010
gastrulation with mouth forming secondGO:0001702440.010
positive regulation of cytoskeleton organizationGO:005149530.010
positive regulation of stem cell proliferationGO:200064810.010
negative regulation of epithelial cell proliferationGO:005068010.010
germ line stem cell maintenanceGO:003071820.010
negative regulation of mapk cascadeGO:004340940.010
chloride transmembrane transportGO:190247640.010
eye morphogenesisGO:00485921440.010
determination of bilateral symmetryGO:00098552040.010
cytokinesisGO:000091030.010
negative regulation of cytoplasmic transportGO:190365020.010
positive regulation of response to stimulusGO:0048584800.010
compound eye developmentGO:004874920.010
dicarboxylic acid transportGO:000683510.010

LOC100005454 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
disease of metabolismDOID:001466700.015
nervous system diseaseDOID:86300.013
inherited metabolic disorderDOID:65500.013
musculoskeletal system diseaseDOID:1700.011