Danio rerio

0 known processes

wdr4

WD repeat domain 4

(Aliases: im:6900357,si:ch211-140m22.6)

wdr4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.076
agingGO:000756820.052
multicellular organism growthGO:003526440.046
regulation of multicellular organism growthGO:004001440.041
nitrogen compound metabolic processGO:00068073190.038
positive regulation of transportGO:005105020.037
maintenance of locationGO:005123540.036
amine metabolic processGO:000930820.036
positive regulation of cellular component biogenesisGO:004408930.034
positive regulation of cell cycleGO:004578730.033
stem cell maintenanceGO:001982740.032
signal transductionGO:00071654550.030
cytokinesisGO:000091030.030
regulation of establishment of protein localizationGO:007020140.030
establishment of protein localization to organelleGO:007259440.030
cellular amine metabolic processGO:004410620.030
regulation of protein transportGO:005122330.030
regulation of cellular amino acid metabolic processGO:000652100.029
nucleocytoplasmic transportGO:000691340.029
cellular ketone metabolic processGO:0042180110.029
nuclear transportGO:005116940.029
phagocytosisGO:000690930.028
regulation of cytokine productionGO:000181730.028
mitochondrion organizationGO:000700540.028
cellular macromolecule metabolic processGO:00442603910.027
negative regulation of protein phosphorylationGO:000193340.027
regulation of cellular amine metabolic processGO:003323800.027
autophagyGO:000691440.027
stem cell proliferationGO:007208940.027
cognitionGO:005089010.027
response to chemicalGO:00422213200.026
positive regulation of catabolic processGO:000989640.026
lipid storageGO:001991510.026
guanosine containing compound catabolic processGO:190106920.025
synaptic growth at neuromuscular junctionGO:005112420.025
guanosine containing compound metabolic processGO:190106840.025
cellular aromatic compound metabolic processGO:00067252950.025
meiotic nuclear divisionGO:000712640.025
cell surface receptor signaling pathwayGO:00071663250.025
proteolysis involved in cellular protein catabolic processGO:005160330.025
cellular nitrogen compound metabolic processGO:00346412900.024
regulation of cellular ketone metabolic processGO:001056570.024
regulation of protein catabolic processGO:004217610.024
extrinsic apoptotic signaling pathwayGO:009719130.024
ribonucleoside monophosphate catabolic processGO:000915840.024
ubiquitin dependent protein catabolic processGO:000651130.024
protein acetylationGO:000647320.024
cellular response to external stimulusGO:007149620.023
organic cyclic compound metabolic processGO:19013603010.023
gtp metabolic processGO:004603940.023
heterocycle metabolic processGO:00464832900.023
modification dependent macromolecule catabolic processGO:004363230.023
cell morphogenesisGO:00009022890.023
gtp catabolic processGO:000618420.023
protein localization to nucleusGO:003450430.023
cellular component morphogenesisGO:00329893360.023
atp catabolic processGO:000620040.023
cell substrate adhesionGO:003158940.023
regulation of macromolecule metabolic processGO:00602553170.022
modification dependent protein catabolic processGO:001994130.022
regulation of peptidyl tyrosine phosphorylationGO:005073010.022
regulation of cell activationGO:005086510.022
cellular protein catabolic processGO:004425740.022
rna localizationGO:000640340.022
regulation of cytoplasmic transportGO:190364940.022
regulation of metal ion transportGO:001095940.022
single organism membrane fusionGO:004480120.022
regulation of protein complex assemblyGO:004325430.022
generation of neuronsGO:00486993850.021
nucleobase containing compound metabolic processGO:00061392740.021
rna metabolic processGO:00160702190.021
proteasomal protein catabolic processGO:001049820.021
cellular response to nutrient levelsGO:003166920.021
nuclear importGO:005117030.021
positive regulation of cellular catabolic processGO:003133130.021
endosomal transportGO:001619720.021
protein importGO:001703830.021
cellular carbohydrate metabolic processGO:004426240.021
regulation of neural precursor cell proliferationGO:200017730.021
organic substance biosynthetic processGO:19015762890.021
regulation of response to stimulusGO:00485832690.021
organic acid metabolic processGO:0006082310.021
protein targeting to nucleusGO:004474430.021
negative regulation of kinase activityGO:003367340.021
purine ribonucleoside monophosphate catabolic processGO:000916940.021
cellular response to extracellular stimulusGO:003166820.021
cytoskeleton dependent cytokinesisGO:006164030.021
single organism nuclear importGO:190259330.021
leukocyte proliferationGO:007066110.020
peptidyl lysine acetylationGO:001839420.020
single organism metabolic processGO:00447102170.020
cellular amino acid metabolic processGO:000652070.020
positive regulation of protein complex assemblyGO:003133420.020
purine nucleoside monophosphate catabolic processGO:000912840.020
eye developmentGO:00016542770.020
regulation of mrna processingGO:005068430.020
regulation of autophagyGO:001050630.020
nucleoside monophosphate catabolic processGO:000912540.020
small molecule metabolic processGO:0044281770.020
neuron differentiationGO:00301823530.020
organonitrogen compound metabolic processGO:1901564740.020
positive regulation of secretion by cellGO:190353210.020
protein import into nucleusGO:000660630.020
meiotic cell cycle processGO:190304630.020
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.020
positive regulation of cellular amino acid metabolic processGO:004576400.020
response to drugGO:004249330.020
gene expressionGO:00104672520.020
negative regulation of protein kinase activityGO:000646940.020
regulation of reproductive processGO:200024140.020
membrane fusionGO:006102520.020
regulation of intracellular protein transportGO:003315730.020
internal protein amino acid acetylationGO:000647520.019
carboxylic acid metabolic processGO:0019752220.019
negative regulation of cellular processGO:00485232830.019
regulation of protein modification by small protein conjugation or removalGO:190332030.019
cell part morphogenesisGO:00329902460.019
centrosome organizationGO:005129710.019
cellular component movementGO:00069283350.019
internal peptidyl lysine acetylationGO:001839320.019
golgi vesicle transportGO:004819330.019
response to stressGO:00069502630.019
nucleic acid metabolic processGO:00903042440.019
negative regulation of biological processGO:00485193040.019
positive regulation of secretionGO:005104710.019
sensory organ developmentGO:00074233930.019
mononuclear cell proliferationGO:003294310.019
regulation of bindingGO:005109830.019
protein localization to plasma membraneGO:007265910.019
regulation of gene expressionGO:00104682650.019
organelle fusionGO:004828430.019
female sex differentiationGO:004666040.019
regulation of metabolic processGO:00192223590.018
cellular nitrogen compound biosynthetic processGO:00442712180.018
exocytosisGO:000688710.018
morphogenesis of an epitheliumGO:00020093330.018
tissue remodelingGO:004877140.018
establishment of localizationGO:00512342440.018
regulation of primary metabolic processGO:00800903110.018
cell projection morphogenesisGO:00488582440.018
regulation of stem cell proliferationGO:007209120.018
protein acylationGO:004354330.018
oxoacid metabolic processGO:0043436310.018
regulation of cell shapeGO:000836010.018
regulation of nucleoside metabolic processGO:000911820.018
regulation of protein ubiquitinationGO:003139630.018
response to uvGO:000941130.018
cellular component disassemblyGO:002241110.018
regulation of nitrogen compound metabolic processGO:00511712510.018
immune system processGO:00023762410.018
regulation of synapse organizationGO:005080730.018
protein metabolic processGO:00195381830.018
regulation of synapse assemblyGO:005196330.018
microtubule organizing center organizationGO:003102310.018
erk1 and erk2 cascadeGO:007037140.017
somatic muscle developmentGO:000752540.017
regulation of erk1 and erk2 cascadeGO:007037240.017
regulation of nucleocytoplasmic transportGO:004682220.017
regulation of purine nucleotide catabolic processGO:003312120.017
cell projection organizationGO:00300302840.017
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
nuclear exportGO:005116810.017
compound eye developmentGO:004874920.017
regulation of cellular metabolic processGO:00313233200.017
regulation of multicellular organismal processGO:00512392770.017
adult behaviorGO:003053420.017
tube morphogenesisGO:00352393490.017
positive regulation of cellular amine metabolic processGO:003324000.017
glucose homeostasisGO:004259310.017
positive regulation of cytoskeleton organizationGO:005149530.017
double strand break repairGO:000630230.017
negative regulation of catabolic processGO:000989530.017
protein dephosphorylationGO:000647030.017
regulation of protein targetingGO:190353320.017
locomotor rhythmGO:004547530.017
establishment of protein localization to plasma membraneGO:009000210.017
neuron developmentGO:00486662620.017
digestive system developmentGO:00551232890.017
positive regulation of cell activationGO:005086710.016
cellular biosynthetic processGO:00442492860.016
regulation of signalingGO:00230512350.016
positive regulation of cytokine productionGO:000181920.016
cell cycle g1 s phase transitionGO:004484310.016
protein heterooligomerizationGO:005129110.016
germ line stem cell maintenanceGO:003071820.016
regulation of developmental processGO:00507932470.016
regulation of biological qualityGO:00650082630.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
organelle organizationGO:00069962270.016
regulation of mrna splicing via spliceosomeGO:004802430.016
embryonic organ developmentGO:00485683810.016
transportGO:00068102200.016
lymphocyte proliferationGO:004665110.016
organic cyclic compound biosynthetic processGO:19013622230.016
regulation of biosynthetic processGO:00098892500.016
stem cell divisionGO:001714510.016
adherens junction organizationGO:003433240.016
head developmentGO:00603223030.016
regulation of signal transductionGO:00099662250.016
system processGO:00030081850.016
regulation of nucleotide catabolic processGO:003081120.016
positive regulation of dna metabolic processGO:005105410.016
negative regulation of mapk cascadeGO:004340940.016
regulation of cell communicationGO:00106462320.016
i kappab kinase nf kappab signalingGO:000724940.016
spermatid developmentGO:000728620.016
heterocycle biosynthetic processGO:00181302150.016
biosynthetic processGO:00090582940.016
regulation of dendrite developmentGO:005077330.016
negative regulation of protein transportGO:005122430.016
response to carbohydrateGO:000974330.016
central nervous system developmentGO:00074173870.016
positive regulation of erk1 and erk2 cascadeGO:007037420.016
cellular response to starvationGO:000926710.016
nucleic acid templated transcriptionGO:00976591810.015
peptidyl serine phosphorylationGO:001810510.015
regulation of gtp catabolic processGO:003312420.015
g1 s transition of mitotic cell cycleGO:000008210.015
regulation of gtpase activityGO:004308720.015
alcohol biosynthetic processGO:004616520.015
locomotionGO:00400113130.015
cellular response to biotic stimulusGO:007121630.015
regulation of rna metabolic processGO:00512522240.015
regulation of jak stat cascadeGO:004642530.015
positive regulation of biological processGO:00485182530.015
cell matrix adhesionGO:000716040.015
regulation of meiotic cell cycleGO:005144510.015
organic acid catabolic processGO:001605430.015
blood vessel morphogenesisGO:00485142160.015
regulation of inflammatory responseGO:005072720.015
regulation of protein localization to nucleusGO:190018020.015
b cell activationGO:004211320.015
fertilizationGO:000956630.015
digestive tract morphogenesisGO:00485462310.015
negative regulation of cytokine productionGO:000181810.015
primary neural tube formationGO:001402010.015
protein secretionGO:000930610.015
response to external stimulusGO:00096052640.015
regulation of stem cell differentiationGO:200073640.015
localization of cellGO:00516742440.015
cellular component biogenesisGO:00440851780.015
regulation of synaptic plasticityGO:004816710.015
cellular response to oxygen levelsGO:007145310.015
single organism transportGO:00447652060.015
camera type eye developmentGO:00430102220.014
aromatic compound biosynthetic processGO:00194382170.014
neuron neuron synaptic transmissionGO:000727010.014
gastrulationGO:00073692080.014
positive regulation of cell adhesionGO:004578510.014
immune system developmentGO:00025201910.014
vasculature developmentGO:00019442780.014
nucleobase containing compound biosynthetic processGO:00346542050.014
rna biosynthetic processGO:00327741810.014
cellular response to chemical stimulusGO:00708871570.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
phagocytosis engulfmentGO:000691110.014
cortical cytoskeleton organizationGO:003086510.014
positive regulation of i kappab kinase nf kappab signalingGO:004312330.014
digestive tract developmentGO:00485652650.014
positive regulation of translationGO:004572710.014
regionalizationGO:00030022740.014
regulation of macromolecule biosynthetic processGO:00105562250.014
signal transduction in absence of ligandGO:003803410.014
cell migrationGO:00164772370.014
macromolecule biosynthetic processGO:00090592270.014
response to hexoseGO:000974630.014
response to glucoseGO:000974930.014
positive regulation of immune effector processGO:000269930.014
regulation of protein import into nucleusGO:004230620.014
meiotic chromosome segregationGO:004513230.014
spermatid differentiationGO:004851520.014
heart developmentGO:00075073130.014
transcription dna templatedGO:00063511810.014
cellular macromolecule biosynthetic processGO:00346452240.014
cellular component assemblyGO:00226071700.014
cellular transition metal ion homeostasisGO:004691630.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
macromolecular complex disassemblyGO:003298410.014
single fertilizationGO:000733830.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
secondary metabolic processGO:001974830.014
single organism localizationGO:19025782250.014
response to monosaccharideGO:003428430.014
positive regulation of nucleotide catabolic processGO:003081310.014
double strand break repair via homologous recombinationGO:000072410.014
cellular response to hypoxiaGO:007145610.014
regulation of multicellular organismal developmentGO:20000262230.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
blood vessel developmentGO:00015682460.013
cellular response to radiationGO:007147840.013
cell morphogenesis involved in differentiationGO:00009041950.013
development of primary female sexual characteristicsGO:004654540.013
regulation of cellular protein catabolic processGO:190336210.013
macroautophagyGO:001623610.013
single organism organelle organizationGO:19025891990.013
regulation of organelle assemblyGO:190211540.013
lateral inhibitionGO:004633110.013
negative regulation of cellular catabolic processGO:003133030.013
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.013
brain developmentGO:00074202930.013
membrane invaginationGO:001032410.013
release of sequestered calcium ion into cytosolGO:005120930.013
regulation of alternative mrna splicing via spliceosomeGO:000038110.013
alternative mrna splicing via spliceosomeGO:000038010.013
positive regulation of map kinase activityGO:004340630.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
recombinational repairGO:000072510.013
production of molecular mediator of immune responseGO:000244020.013
carbohydrate homeostasisGO:003350010.013
cell motilityGO:00488702440.013
actin filament polymerizationGO:003004120.013
cellular amide metabolic processGO:004360340.013
nucleic acid transportGO:005065720.013
positive regulation of nucleoside metabolic processGO:004597910.013
peptidyl serine modificationGO:001820920.013
regulation of cell substrate adhesionGO:001081010.013
neuron projection morphogenesisGO:00488121610.013
mitotic cytokinesisGO:000028130.013
cytosolic calcium ion transportGO:006040130.013
positive regulation of leukocyte mediated immunityGO:000270510.013
actin polymerization or depolymerizationGO:000815420.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
female gonad developmentGO:000858540.013
sequestering of metal ionGO:005123830.013
tube closureGO:006060610.013
regulation of calcium ion transportGO:005192420.013
chordate embryonic developmentGO:00430092710.013
macromolecule modificationGO:00434121110.012
negative regulation of cytoplasmic transportGO:190365020.012
response to corticosteroidGO:003196010.012
hemopoiesisGO:00300971830.012
positive regulation of lymphocyte mediated immunityGO:000270810.012
regulation of epithelial cell proliferationGO:005067830.012
cellular protein metabolic processGO:00442671290.012
sequestering of calcium ionGO:005120830.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
regulation of transporter activityGO:003240920.012
negative regulation of secretionGO:005104820.012
chemosensory behaviorGO:000763510.012
regulation of blood pressureGO:000821710.012
regulation of transcription dna templatedGO:00063552130.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
cell substrate junction assemblyGO:000704420.012
growthGO:00400071740.012
lipid homeostasisGO:005508830.012
peptide transportGO:001583310.012
regulation of rna biosynthetic processGO:20011412130.012
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
response to hydrogen peroxideGO:004254230.012
rna transportGO:005065820.012
neuroblast proliferationGO:000740520.012
establishment of synaptic vesicle localizationGO:009748010.012
liver developmentGO:0001889960.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
activation of mapk activityGO:000018730.012
mitochondrial transportGO:000683920.012
regulation of dna replicationGO:000627530.012
cell cycle arrestGO:000705010.012
cilium morphogenesisGO:0060271850.012
cellular response to light stimulusGO:007148240.012
regulation of production of molecular mediator of immune responseGO:000270010.012
regulation of response to nutrient levelsGO:003210710.012
neurotransmitter transportGO:000683620.012
regulation of tube sizeGO:003515020.012
antimicrobial humoral responseGO:001973020.012
negative regulation of sequestering of calcium ionGO:005128340.012
rna 3 end processingGO:003112320.012
embryo development ending in birth or egg hatchingGO:00097922710.012
protein complex disassemblyGO:004324110.012
regulation of ion transmembrane transporter activityGO:003241220.012
regulation of jun kinase activityGO:004350630.012
regulation of sequestering of calcium ionGO:005128240.012
cellular response to decreased oxygen levelsGO:003629410.012
positive regulation of gtp catabolic processGO:003312610.012
homeostatic processGO:00425921420.012
positive regulation of cellular processGO:00485222010.012
protein polymerizationGO:005125840.012
angiogenesisGO:00015251580.012
negative regulation of secretion by cellGO:190353120.012
sensory perception of painGO:001923310.012
response to organic substanceGO:00100331530.011
positive regulation of gtpase activityGO:004354710.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
er to golgi vesicle mediated transportGO:000688810.011
nucleobase containing compound transportGO:001593120.011
response to nutrientGO:000758430.011
post embryonic organ developmentGO:004856940.011
transcription from rna polymerase ii promoterGO:0006366800.011
regulation of cellular biosynthetic processGO:00313262450.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
centrosome cycleGO:000709810.011
response to alkaloidGO:004327920.011
interspecies interaction between organismsGO:004441940.011
protein homooligomerizationGO:005126030.011
multi organism processGO:00517041340.011
cell deathGO:00082191210.011
regulation of circadian rhythmGO:004275240.011
axon developmentGO:00615641660.011
intracellular mrna localizationGO:000829810.011
synaptic vesicle transportGO:004848910.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
small molecule catabolic processGO:004428230.011
developmental growthGO:00485891660.011
regulation of response to extracellular stimulusGO:003210410.011
positive regulation of synapse assemblyGO:005196510.011
cellular response to organic substanceGO:00713101050.011
viral processGO:001603210.011
dna templated transcription elongationGO:000635430.011
rna modificationGO:000945120.011
negative regulation of nuclear divisionGO:005178430.011
cellular biogenic amine metabolic processGO:000657620.011
retina development in camera type eyeGO:00600411460.011
positive regulation of chromosome organizationGO:200125210.011
carbohydrate biosynthetic processGO:001605110.011
intracellular signal transductionGO:0035556850.011
cytoplasm organizationGO:000702840.011
organism emergence from protective structureGO:007168440.011
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.011
regulation of receptor activityGO:001046920.011
response to woundingGO:00096111160.011
axonogenesisGO:00074091520.011
positive regulation of stress activated mapk cascadeGO:003287430.011
protein modification processGO:00362111000.011
synaptic vesicle localizationGO:009747910.011
regulation of transmembrane transporter activityGO:002289820.011
positive regulation of notch signaling pathwayGO:004574730.011
lipid catabolic processGO:001604240.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
sensory perception of chemical stimulusGO:000760630.011
centrosome duplicationGO:005129810.011
cellular response to lipopolysaccharideGO:007122230.011
bone remodelingGO:004684920.010
regulation of dendrite morphogenesisGO:004881430.010
response to glucocorticoidGO:005138410.010
muscle structure developmentGO:00610611960.010
vacuolar transportGO:000703420.010
cellular protein modification processGO:00064641000.010
response to abiotic stimulusGO:00096281220.010
actin filament based movementGO:003004810.010
negative regulation of intracellular protein transportGO:009031730.010
neuron projection developmentGO:00311751800.010
negative regulation of neural precursor cell proliferationGO:200017810.010
regulation of protein bindingGO:004339330.010
deathGO:00162651210.010
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.010
negative regulation of defense responseGO:003134820.010
positive regulation of jak stat cascadeGO:004642720.010
negative regulation of nucleocytoplasmic transportGO:004682320.010
dna templated transcription initiationGO:000635210.010
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.010
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.010
phosphate containing compound metabolic processGO:00067961080.010
hormone secretionGO:004687920.010
developmental programmed cell deathGO:001062340.010
calcium ion transport into cytosolGO:006040230.010
positive regulation of neuron apoptotic processGO:004352510.010
regulation of response to biotic stimulusGO:000283120.010
multi organism cellular processGO:004476420.010
dorsal ventral pattern formationGO:00099531250.010
negative regulation of multi organism processGO:004390130.010
positive regulation of chromatin modificationGO:190331010.010
protein polyubiquitinationGO:000020940.010
positive regulation of lipid metabolic processGO:004583410.010

wdr4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.048
nervous system diseaseDOID:86300.021
disease of metabolismDOID:001466700.020
musculoskeletal system diseaseDOID:1700.019
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
organ system cancerDOID:005068600.017
muscle tissue diseaseDOID:6600.013
muscular diseaseDOID:008000000.013
myopathyDOID:42300.013
cardiomyopathyDOID:005070000.012
cardiovascular system diseaseDOID:128700.012
intrinsic cardiomyopathyDOID:006003600.012
heart diseaseDOID:11400.012
immune system diseaseDOID:291400.012
inherited metabolic disorderDOID:65500.012